Structural position:
- Domain Type: Fn3
- Aligned Position: 104
- Secondary Structure Element: e
- Secondary Structure Region: β-strand F
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Y/S | 15728 |
Fn3-1 |
72 | rs1559849572 |
0.9807 | None | 1.0 | D | 0.894 | 0.911 | 0.9220203 | gnomAD-4.0.0 | 1.59324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86221E-06 | 0 | 0 |
| Y/H | 15829 |
Fn3-2 |
72 | None | 0.8497 | None | 1.0 | D | 0.84 | 0.869 | 0.85443515 | gnomAD-4.0.0 | 1.59363E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4334E-05 | 0 |
| Y/H | 16225 |
Fn3-5 |
71 | rs781080078 |
0.8077 | -2.483 | 1.0 | D | 0.851 | 0.858 | 0.8041251 | gnomAD-2.1.1 | 1.79E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.03E-05 | 0 |
| Y/H | 16225 |
Fn3-5 |
71 | rs781080078 |
0.8077 | -2.483 | 1.0 | D | 0.851 | 0.858 | 0.8041251 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/H | 16225 |
Fn3-5 |
71 | rs781080078 |
0.8077 | -2.483 | 1.0 | D | 0.851 | 0.858 | 0.8041251 | gnomAD-4.0.0 | 3.93481E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.34804E-06 | 0 | 0 |
| Y/H | 16521 |
Fn3-7 |
72 | rs758275324 |
0.9806 | -2.797 | 1.0 | D | 0.847 | 0.856 | 0.729214 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| Y/H | 16521 |
Fn3-7 |
72 | rs758275324 |
0.9806 | -2.797 | 1.0 | D | 0.847 | 0.856 | 0.729214 | gnomAD-4.0.0 | 2.05678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70103E-06 | 0 | 0 |
| Y/H | 16621 |
Fn3-8 |
71 | rs766377448 |
0.9893 | -2.437 | 1.0 | D | 0.847 | 0.894 | 0.78706235 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| Y/H | 16621 |
Fn3-8 |
71 | rs766377448 |
0.9893 | -2.437 | 1.0 | D | 0.847 | 0.894 | 0.78706235 | gnomAD-4.0.0 | 3.18769E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86697E-05 | 0 |
| Y/C | 16721 |
Fn3-9 |
71 | None | 0.9294 | None | 1.0 | D | 0.863 | 0.884 | 0.92667204 | gnomAD-4.0.0 | 1.36945E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79979E-06 | 0 | 0 |
| Y/C | 16924 |
Fn3-11 |
73 | rs768626961 |
0.9551 | -2.144 | 1.0 | D | 0.871 | 0.849 | 0.93172985 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/C | 16924 |
Fn3-11 |
73 | rs768626961 |
0.9551 | -2.144 | 1.0 | D | 0.871 | 0.849 | 0.93172985 | gnomAD-4.0.0 | 1.59306E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| Y/F | 16924 |
Fn3-11 |
73 | rs768626961 |
0.3348 | -1.244 | 0.999 | D | 0.739 | 0.811 | 0.8211324 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/F | 16924 |
Fn3-11 |
73 | rs768626961 |
0.3348 | -1.244 | 0.999 | D | 0.739 | 0.811 | 0.8211324 | gnomAD-4.0.0 | 1.59306E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| Y/H | 17441 |
Fn3-14 |
73 | None | 0.9893 | None | 1.0 | D | 0.825 | 0.878 | 0.75093985 | gnomAD-4.0.0 | 1.59462E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86328E-06 | 0 | 0 |
| Y/C | 17540 |
Fn3-15 |
71 | rs1013723159 |
0.928 | None | 1.0 | D | 0.863 | 0.905 | 0.89761937 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 17540 |
Fn3-15 |
71 | rs1013723159 |
0.928 | None | 1.0 | D | 0.863 | 0.905 | 0.89761937 | gnomAD-4.0.0 | 3.10274E-06 | None | None | None | None | N | None | 0 | 1.67191E-05 | None | 0 | 0 | None | 0 | 0 | 1.69663E-06 | 0 | 3.20935E-05 |
| Y/F | 17833 |
Fn3-17 |
70 | None | 0.5418 | None | 0.999 | D | 0.741 | 0.895 | 0.889162 | gnomAD-4.0.0 | 1.36932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79976E-06 | 0 | 0 |
| Y/H | 17833 |
Fn3-17 |
70 | rs1238654352 |
0.9912 | -2.563 | 1.0 | D | 0.827 | 0.916 | 0.77420247 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 17833 |
Fn3-17 |
70 | rs1238654352 |
0.9912 | -2.563 | 1.0 | D | 0.827 | 0.916 | 0.77420247 | gnomAD-4.0.0 | 3.1874E-06 | None | None | None | None | N | None | 0 | 4.57854E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 17933 |
Fn3-18 |
72 | rs1271497242 |
0.8729 | None | 1.0 | D | 0.866 | 0.853 | 0.91689205 | gnomAD-4.0.0 | 3.18885E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86993E-05 | 0 |
| Y/H | 18345 |
Fn3-21 |
74 | rs2053680681 |
0.9158 | None | 0.391 | D | 0.607 | 0.805 | 0.6300935 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 18345 |
Fn3-21 |
74 | rs2053680681 |
0.9158 | None | 0.391 | D | 0.607 | 0.805 | 0.6300935 | gnomAD-4.0.0 | 6.57955E-06 | None | None | None | None | N | None | 0 | 6.56426E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 18655 |
Fn3-23 |
77 | rs1391393842 |
0.8249 | None | 1.0 | D | 0.848 | 0.842 | 0.8031983 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 18855 |
Fn3-24 |
72 | None | 0.9746 | None | 1.0 | D | 0.871 | 0.905 | 0.9072324 | gnomAD-4.0.0 | 1.80287E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.14068E-06 | 0 | 0 |
| Y/C | 18959 |
Fn3-25 |
76 | rs775301931 |
0.8945 | -1.942 | 1.0 | D | 0.876 | 0.909 | 0.8778154 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 18959 |
Fn3-25 |
76 | rs775301931 |
0.8945 | -1.942 | 1.0 | D | 0.876 | 0.909 | 0.8778154 | gnomAD-4.0.0 | 3.18448E-06 | None | None | None | None | N | None | 0 | 4.57436E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/D | 18959 |
Fn3-25 |
76 | rs753144774 |
0.9958 | -3.212 | 1.0 | D | 0.883 | 0.929 | 0.94575363 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65948E-04 |
| Y/N | 18959 |
Fn3-25 |
76 | rs753144774 |
0.9633 | -2.714 | 1.0 | D | 0.877 | 0.926 | None | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| Y/N | 18959 |
Fn3-25 |
76 | rs753144774 |
0.9633 | -2.714 | 1.0 | D | 0.877 | 0.926 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 8.83E-05 | 0 | 0 |
| Y/N | 18959 |
Fn3-25 |
76 | rs753144774 |
0.9633 | -2.714 | 1.0 | D | 0.877 | 0.926 | None | gnomAD-4.0.0 | 6.13665E-05 | None | None | None | None | N | None | 2.67087E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.13883E-05 | 0 | 1.60138E-05 |
| Y/N | 19254 |
Fn3-27 |
72 | None | 0.9543 | None | 1.0 | D | 0.875 | 0.899 | 0.9183094 | gnomAD-4.0.0 | 1.66373E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.986E-06 | 0 | 0 |
| Y/C | 19355 |
Fn3-28 |
72 | rs766593902 |
0.5564 | -1.884 | 1.0 | D | 0.823 | 0.835 | 0.9328939 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 5.82E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/C | 19355 |
Fn3-28 |
72 | rs766593902 |
0.5564 | -1.884 | 1.0 | D | 0.823 | 0.835 | 0.9328939 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 19355 |
Fn3-28 |
72 | rs766593902 |
0.5564 | -1.884 | 1.0 | D | 0.823 | 0.835 | 0.9328939 | gnomAD-4.0.0 | 9.92088E-06 | None | None | None | None | N | None | 0 | 3.33868E-05 | None | 0 | 0 | None | 0 | 0 | 1.10229E-05 | 1.10011E-05 | 0 |
| Y/F | 19355 |
Fn3-28 |
72 | None | 0.1179 | None | 0.994 | D | 0.704 | 0.748 | 0.7899984 | gnomAD-4.0.0 | 6.84634E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99798E-07 | 0 | 0 |
| Y/C | 19550 |
Fn3-29 |
72 | rs770314252 |
0.8434 | -1.652 | 1.0 | D | 0.877 | 0.857 | 0.8955645 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| Y/C | 19550 |
Fn3-29 |
72 | rs770314252 |
0.8434 | -1.652 | 1.0 | D | 0.877 | 0.857 | 0.8955645 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 19550 |
Fn3-29 |
72 | rs770314252 |
0.8434 | -1.652 | 1.0 | D | 0.877 | 0.857 | 0.8955645 | gnomAD-4.0.0 | 1.17788E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23894E-05 | None | 0 | 0 | 1.44118E-05 | 0 | 1.60195E-05 |
| Y/D | 19550 |
Fn3-29 |
72 | None | 0.9863 | None | 1.0 | D | 0.877 | 0.896 | 0.8374686 | gnomAD-4.0.0 | 1.59279E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43336E-05 | 0 |
| Y/H | 19550 |
Fn3-29 |
72 | rs2154186587 |
0.9406 | None | 1.0 | D | 0.818 | 0.862 | 0.80290633 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/H | 19550 |
Fn3-29 |
72 | rs2154186587 |
0.9406 | None | 1.0 | D | 0.818 | 0.862 | 0.80290633 | gnomAD-4.0.0 | 2.56394E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78854E-06 | 0 | 0 |
| Y/C | 19753 |
Fn3-31 |
74 | rs755651839 |
0.6504 | -1.391 | 0.265 | D | 0.74 | 0.711 | 0.8772425 | gnomAD-2.1.1 | 2.14E-05 | None | None | None | None | N | None | 1.23987E-04 | 5.66E-05 | None | 0 | 0 | None | 0 | None | 0 | 7.82E-06 | 0 |
| Y/C | 19753 |
Fn3-31 |
74 | rs755651839 |
0.6504 | -1.391 | 0.265 | D | 0.74 | 0.711 | 0.8772425 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 19753 |
Fn3-31 |
74 | rs755651839 |
0.6504 | -1.391 | 0.265 | D | 0.74 | 0.711 | 0.8772425 | gnomAD-4.0.0 | 8.05749E-06 | None | None | None | None | N | None | 5.34031E-05 | 3.33522E-05 | None | 0 | 2.23184E-05 | None | 0 | 0 | 5.08639E-06 | 0 | 0 |
| Y/H | 19947 |
Fn3-32 |
71 | rs1288648449 |
0.9256 | -2.615 | 0.999 | D | 0.792 | 0.849 | 0.830804 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 19947 |
Fn3-32 |
71 | rs1288648449 |
0.9256 | -2.615 | 0.999 | D | 0.792 | 0.849 | 0.830804 | gnomAD-4.0.0 | 1.59292E-06 | None | None | None | None | N | None | 0 | 2.29032E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 20046 |
Fn3-33 |
70 | rs1290494704 |
0.2083 | -1.038 | 0.999 | D | 0.759 | 0.774 | 0.88918644 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/F | 20046 |
Fn3-33 |
70 | rs1290494704 |
0.2083 | -1.038 | 0.999 | D | 0.759 | 0.774 | 0.88918644 | gnomAD-4.0.0 | 1.5919E-06 | None | None | None | None | N | None | 0 | 2.28707E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 20242 |
Fn3-34 |
72 | None | 0.9685 | None | 1.0 | D | 0.865 | 0.882 | 0.93088305 | gnomAD-4.0.0 | 1.5919E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85977E-06 | 0 | 0 |
| Y/H | 20242 |
Fn3-34 |
72 | None | 0.9777 | None | 1.0 | D | 0.823 | 0.868 | 0.8474664 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| Y/C | 20341 |
Fn3-35 |
71 | rs2050021727 |
0.8098 | None | 1.0 | D | 0.839 | 0.882 | 0.92343485 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 20341 |
Fn3-35 |
71 | rs2050021727 |
0.8098 | None | 1.0 | D | 0.839 | 0.882 | 0.92343485 | gnomAD-4.0.0 | 6.57523E-06 | None | None | None | None | N | None | 0 | 6.5548E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 20341 |
Fn3-35 |
71 | None | 0.2849 | None | 0.999 | D | 0.751 | 0.834 | 0.8076772 | gnomAD-4.0.0 | 3.18575E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72243E-06 | 0 | 0 |
| Y/H | 20443 |
Fn3-36 |
73 | rs781630562 |
0.9744 | -2.694 | 1.0 | D | 0.818 | 0.835 | 0.74058455 | gnomAD-2.1.1 | 8.31E-06 | None | None | None | None | N | None | 0 | 2.97E-05 | None | 0 | 0 | None | 0 | None | 0 | 9.12E-06 | 0 |
| Y/H | 20443 |
Fn3-36 |
73 | rs781630562 |
0.9744 | -2.694 | 1.0 | D | 0.818 | 0.835 | 0.74058455 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| Y/H | 20443 |
Fn3-36 |
73 | rs781630562 |
0.9744 | -2.694 | 1.0 | D | 0.818 | 0.835 | 0.74058455 | gnomAD-4.0.0 | 3.23907E-05 | None | None | None | None | N | None | 1.34009E-05 | 1.68868E-05 | None | 0 | 0 | None | 0 | 0 | 4.08005E-05 | 1.12539E-05 | 1.61015E-05 |
| Y/N | 20443 |
Fn3-36 |
73 | rs781630562 |
0.9662 | None | 1.0 | D | 0.907 | 0.859 | 0.8303902 | gnomAD-4.0.0 | 1.3761E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80428E-06 | 0 | 0 |
| Y/H | 20638 |
Fn3-37 |
70 | rs777982609 |
0.9861 | -2.76 | 1.0 | D | 0.819 | 0.853 | 0.8489875 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 20638 |
Fn3-37 |
70 | rs777982609 |
0.9861 | -2.76 | 1.0 | D | 0.819 | 0.853 | 0.8489875 | gnomAD-4.0.0 | 1.59183E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77577E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 20739 |
Fn3-38 |
72 | rs751502535 |
0.692 | -1.507 | 1.0 | D | 0.875 | 0.766 | 0.89729655 | gnomAD-2.1.1 | 7.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| Y/C | 20739 |
Fn3-38 |
72 | rs751502535 |
0.692 | -1.507 | 1.0 | D | 0.875 | 0.766 | 0.89729655 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| Y/C | 20739 |
Fn3-38 |
72 | rs751502535 |
0.692 | -1.507 | 1.0 | D | 0.875 | 0.766 | 0.89729655 | gnomAD-4.0.0 | 4.33895E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93404E-06 | 0 | 0 |
| Y/F | 20739 |
Fn3-38 |
72 | rs751502535 |
0.1404 | -1.336 | 0.999 | D | 0.756 | 0.742 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/F | 20739 |
Fn3-38 |
72 | rs751502535 |
0.1404 | -1.336 | 0.999 | D | 0.756 | 0.742 | None | gnomAD-4.0.0 | 1.36874E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99562E-07 | 0 | 1.65711E-05 |
| Y/C | 20934 |
Fn3-39 |
71 | rs568688685 |
0.9904 | -2.078 | 1.0 | D | 0.872 | 0.839 | 0.8878919 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| Y/C | 20934 |
Fn3-39 |
71 | rs568688685 |
0.9904 | -2.078 | 1.0 | D | 0.872 | 0.839 | 0.8878919 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | N | None | 8.28E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 20934 |
Fn3-39 |
71 | rs568688685 |
0.9904 | -2.078 | 1.0 | D | 0.872 | 0.839 | 0.8878919 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 20934 |
Fn3-39 |
71 | rs568688685 |
0.9904 | -2.078 | 1.0 | D | 0.872 | 0.839 | 0.8878919 | gnomAD-4.0.0 | 4.05968E-06 | None | None | None | None | N | None | 6.9752E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 21034 |
Fn3-40 |
72 | None | 0.9553 | None | 1.0 | D | 0.862 | 0.854 | 0.88638747 | gnomAD-4.0.0 | 3.26606E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.82992E-06 | 0 | 0 |
| Y/C | 21141 |
Fn3-41 |
78 | rs762123565 |
0.8851 | -2.189 | 1.0 | D | 0.791 | 0.875 | 0.9310941 | gnomAD-2.1.1 | 8.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.13276E-04 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 21141 |
Fn3-41 |
78 | rs762123565 |
0.8851 | -2.189 | 1.0 | D | 0.791 | 0.875 | 0.9310941 | gnomAD-4.0.0 | 3.18897E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58878E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 21336 |
Fn3-42 |
71 | None | 0.9147 | None | 1.0 | D | 0.867 | 0.911 | 0.87681186 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/F | 22026 |
Fn3-47 |
71 | rs1298916237 |
0.8095 | -1.27 | 0.999 | D | 0.751 | 0.86 | 0.86174625 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| Y/F | 22026 |
Fn3-47 |
71 | rs1298916237 |
0.8095 | -1.27 | 0.999 | D | 0.751 | 0.86 | 0.86174625 | gnomAD-4.0.0 | 3.18774E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.872E-05 | 0 |
| Y/H | 22026 |
Fn3-47 |
71 | None | 0.9987 | None | 1.0 | D | 0.851 | 0.848 | 0.7921188 | gnomAD-4.0.0 | 1.59393E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.77373E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 22126 |
Fn3-48 |
72 | rs1447894010 |
0.9662 | -2.042 | 1.0 | D | 0.832 | 0.848 | 0.73059016 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| Y/H | 22126 |
Fn3-48 |
72 | rs1447894010 |
0.9662 | -2.042 | 1.0 | D | 0.832 | 0.848 | 0.73059016 | gnomAD-4.0.0 | 8.21273E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.04275E-03 | 4.49835E-06 | 0 | 1.65717E-05 |
| Y/H | 22228 |
Fn3-49 |
73 | rs1170889599 |
0.9797 | -2.211 | 1.0 | D | 0.853 | 0.838 | 0.84085935 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.63E-05 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 22228 |
Fn3-49 |
73 | rs1170889599 |
0.9797 | -2.211 | 1.0 | D | 0.853 | 0.838 | 0.84085935 | gnomAD-4.0.0 | 1.59384E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78722E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 22424 |
Fn3-50 |
71 | rs1479907727 |
0.83 | None | 1.0 | D | 0.865 | 0.776 | 0.91860545 | gnomAD-4.0.0 | 1.59226E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| Y/H | 22424 |
Fn3-50 |
71 | rs974697497 |
0.9372 | -2.408 | 0.999 | D | 0.809 | 0.893 | 0.83657545 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Y/H | 22424 |
Fn3-50 |
71 | rs974697497 |
0.9372 | -2.408 | 0.999 | D | 0.809 | 0.893 | 0.83657545 | gnomAD-4.0.0 | 3.42199E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49832E-06 | 0 | 0 |
| Y/N | 22424 |
Fn3-50 |
71 | None | 0.9561 | None | 0.999 | D | 0.869 | 0.846 | 0.9460781 | gnomAD-4.0.0 | 6.84399E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73671E-04 | 0 | 0 | 0 |
| Y/S | 22424 |
Fn3-50 |
71 | rs1479907727 |
0.9521 | -3.668 | 0.997 | D | 0.88 | 0.788 | 0.9237926 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/D | 22519 |
Fn3-51 |
69 | rs779007987 |
0.9755 | -3.311 | 1.0 | D | 0.887 | 0.917 | 0.9218351 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/D | 22519 |
Fn3-51 |
69 | rs779007987 |
0.9755 | -3.311 | 1.0 | D | 0.887 | 0.917 | 0.9218351 | gnomAD-4.0.0 | 6.15957E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19748E-06 | 0 | 1.65717E-05 |
| Y/C | 22912 |
Fn3-54 |
72 | rs757919433 |
0.728 | -1.744 | 0.241 | D | 0.725 | 0.699 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 1.65412E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 22912 |
Fn3-54 |
72 | rs757919433 |
0.728 | -1.744 | 0.241 | D | 0.725 | 0.699 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20616E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 22912 |
Fn3-54 |
72 | rs757919433 |
0.728 | -1.744 | 0.241 | D | 0.725 | 0.699 | None | gnomAD-4.0.0 | 7.69114E-06 | None | None | None | None | N | None | 1.01488E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/D | 23505 |
Fn3-58 |
71 | None | 0.9935 | None | 1.0 | D | 0.86 | 0.887 | 0.8951231 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/C | 23601 |
Fn3-59 |
70 | rs1421650962 |
0.8844 | None | 1.0 | D | 0.869 | 0.841 | 0.88949716 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| Y/C | 23601 |
Fn3-59 |
70 | rs1421650962 |
0.8844 | None | 1.0 | D | 0.869 | 0.841 | 0.88949716 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| Y/C | 23601 |
Fn3-59 |
70 | rs1421650962 |
0.8844 | None | 1.0 | D | 0.869 | 0.841 | 0.88949716 | gnomAD-4.0.0 | 7.10501E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.43477E-06 | 0 | 0 |
| Y/N | 23601 |
Fn3-59 |
70 | None | 0.9288 | None | 1.0 | D | 0.863 | 0.851 | 0.91939664 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/S | 23601 |
Fn3-59 |
70 | rs1421650962 |
0.9775 | None | 1.0 | D | 0.872 | 0.873 | 0.9036392 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/S | 23601 |
Fn3-59 |
70 | rs1421650962 |
0.9775 | None | 1.0 | D | 0.872 | 0.873 | 0.9036392 | gnomAD-4.0.0 | 6.5741E-06 | None | None | None | None | N | None | 2.41289E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 23897 |
Fn3-61 |
72 | None | 0.6852 | None | 1.0 | D | 0.873 | 0.923 | 0.87194455 | gnomAD-4.0.0 | 3.18341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 6.04997E-05 |
| Y/F | 23897 |
Fn3-61 |
72 | rs1457146309 |
0.2168 | -0.694 | 0.999 | D | 0.741 | 0.902 | 0.84988385 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| Y/F | 23897 |
Fn3-61 |
72 | rs1457146309 |
0.2168 | -0.694 | 0.999 | D | 0.741 | 0.902 | 0.84988385 | gnomAD-4.0.0 | 1.5917E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77285E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 23897 |
Fn3-61 |
72 | rs1338027065 |
0.9356 | -3.256 | 1.0 | D | 0.87 | 0.909 | 0.8997717 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Y/S | 23897 |
Fn3-61 |
72 | rs1457146309 |
0.9336 | -3.604 | 1.0 | D | 0.879 | 0.913 | 0.88531786 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/S | 23897 |
Fn3-61 |
72 | rs1457146309 |
0.9336 | -3.604 | 1.0 | D | 0.879 | 0.913 | 0.88531786 | gnomAD-4.0.0 | 3.18341E-06 | None | None | None | None | N | None | 0 | 4.57289E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 23995 |
Fn3-62 |
72 | None | 0.921 | None | 1.0 | D | 0.831 | 0.848 | 0.8413637 | gnomAD-4.0.0 | 1.59169E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85909E-06 | 0 | 0 |
| Y/C | 24193 |
Fn3-63 |
72 | None | 0.9788 | None | 1.0 | D | 0.885 | 0.861 | 0.8965312 | gnomAD-4.0.0 | 1.95251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.37437E-06 | 0 | 0 |
| Y/C | 24293 |
Fn3-64 |
72 | None | 0.9122 | None | 1.0 | D | 0.869 | 0.784 | 0.9245928 | gnomAD-4.0.0 | 2.75087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.61167E-06 | 0 | 0 |
| Y/H | 24395 |
Fn3-65 |
73 | rs1489927926 |
0.911 | -2.206 | 1.0 | D | 0.847 | 0.888 | 0.80271727 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
| Y/H | 24395 |
Fn3-65 |
73 | rs1489927926 |
0.911 | -2.206 | 1.0 | D | 0.847 | 0.888 | 0.80271727 | gnomAD-4.0.0 | 1.59254E-06 | None | None | None | None | N | None | 0 | 2.28822E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 24589 |
Fn3-66 |
71 | rs368708895 |
0.9056 | -2.067 | 1.0 | D | 0.851 | 0.822 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Y/C | 24589 |
Fn3-66 |
71 | rs368708895 |
0.9056 | -2.067 | 1.0 | D | 0.851 | 0.822 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 24589 |
Fn3-66 |
71 | rs368708895 |
0.9056 | -2.067 | 1.0 | D | 0.851 | 0.822 | None | gnomAD-4.0.0 | 4.34085E-06 | None | None | None | None | N | None | 4.00555E-05 | 0 | None | 0 | 0 | None | 0 | 3.29381E-04 | 8.48197E-07 | 1.0981E-05 | 0 |
| Y/H | 24589 |
Fn3-66 |
71 | rs371821218 |
0.971 | -2.335 | 1.0 | D | 0.836 | 0.82 | None | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.48E-05 | 0 |
| Y/H | 24589 |
Fn3-66 |
71 | rs371821218 |
0.971 | -2.335 | 1.0 | D | 0.836 | 0.82 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| Y/H | 24589 |
Fn3-66 |
71 | rs371821218 |
0.971 | -2.335 | 1.0 | D | 0.836 | 0.82 | None | gnomAD-4.0.0 | 1.73618E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.20511E-05 | 0 | 3.20431E-05 |
| Y/S | 24685 |
Fn3-67 |
70 | None | 0.9887 | None | 0.992 | D | 0.848 | 0.859 | 0.89897895 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/C | 24879 |
Fn3-68 |
72 | rs933323916 |
0.9791 | None | 1.0 | D | 0.87 | 0.875 | 0.8690545 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 24879 |
Fn3-68 |
72 | rs933323916 |
0.9791 | None | 1.0 | D | 0.87 | 0.875 | 0.8690545 | gnomAD-4.0.0 | 2.56375E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78838E-06 | 0 | 0 |
| Y/H | 24979 |
Fn3-69 |
72 | rs1364199300 |
0.9665 | -2.249 | 1.0 | D | 0.835 | 0.904 | 0.8349732 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 24979 |
Fn3-69 |
72 | rs1364199300 |
0.9665 | -2.249 | 1.0 | D | 0.835 | 0.904 | 0.8349732 | gnomAD-4.0.0 | 2.05292E-06 | None | None | None | None | N | None | 0 | 6.70991E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 24979 |
Fn3-69 |
72 | rs1364199300 |
0.9357 | -3.086 | 1.0 | D | 0.855 | 0.89 | 0.949802 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/N | 24979 |
Fn3-69 |
72 | rs1364199300 |
0.9357 | -3.086 | 1.0 | D | 0.855 | 0.89 | 0.949802 | gnomAD-4.0.0 | 6.84308E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15945E-05 | 0 |
| Y/C | 25077 |
Fn3-70 |
72 | rs1001172074 |
0.7746 | None | 1.0 | D | 0.87 | 0.862 | 0.92239076 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 25077 |
Fn3-70 |
72 | rs1001172074 |
0.7746 | None | 1.0 | D | 0.87 | 0.862 | 0.92239076 | gnomAD-4.0.0 | 1.05365E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.44114E-05 | 0 | 0 |
| Y/H | 25077 |
Fn3-70 |
72 | None | 0.9435 | None | 1.0 | D | 0.849 | 0.831 | 0.8300028 | gnomAD-4.0.0 | 1.59174E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77485E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 25275 |
Fn3-71 |
72 | None | 0.9818 | None | 1.0 | D | 0.897 | 0.938 | 0.8905501 | gnomAD-4.0.0 | 3.18464E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.82393E-04 | 0 | 0 | 0 |
| Y/H | 25275 |
Fn3-71 |
72 | rs1707703238 |
0.9925 | None | 1.0 | D | 0.811 | 0.854 | 0.79707664 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 25275 |
Fn3-71 |
72 | rs1707703238 |
0.9925 | None | 1.0 | D | 0.811 | 0.854 | 0.79707664 | gnomAD-4.0.0 | 4.05994E-06 | None | None | None | None | N | None | 1.74709E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.61485E-06 | 0 | 0 |
| Y/F | 25375 |
Fn3-72 |
72 | rs374494927 |
0.2341 | -1.334 | 0.999 | D | 0.745 | 0.797 | None | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | N | None | 6.46E-05 | 1.45332E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 1.66611E-04 |
| Y/F | 25375 |
Fn3-72 |
72 | rs374494927 |
0.2341 | -1.334 | 0.999 | D | 0.745 | 0.797 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 25375 |
Fn3-72 |
72 | rs374494927 |
0.2341 | -1.334 | 0.999 | D | 0.745 | 0.797 | None | gnomAD-4.0.0 | 8.05959E-06 | None | None | None | None | N | None | 1.33568E-05 | 1.16791E-04 | None | 0 | 0 | None | 0 | 0 | 1.69572E-06 | 0 | 4.80523E-05 |
| Y/N | 25767 |
Fn3-75 |
70 | rs1303024823 |
0.942 | None | 0.996 | D | 0.878 | 0.858 | 0.9419301 | gnomAD-4.0.0 | 2.73781E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52334E-05 | None | 0 | 0 | 0 | 0 | 4.97117E-05 |
| Y/D | 25961 |
Fn3-76 |
72 | rs772167869 |
0.9975 | -3.866 | 1.0 | D | 0.876 | 0.89 | 0.94191843 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| Y/D | 25961 |
Fn3-76 |
72 | rs772167869 |
0.9975 | -3.866 | 1.0 | D | 0.876 | 0.89 | 0.94191843 | gnomAD-4.0.0 | 1.59175E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77516E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 26061 |
Fn3-77 |
72 | None | 0.9177 | None | 1.0 | D | 0.901 | 0.918 | 0.90878093 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| Y/N | 26061 |
Fn3-77 |
72 | None | 0.9504 | None | 1.0 | D | 0.903 | 0.875 | 0.9353621 | gnomAD-4.0.0 | 8.40225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.18751E-06 | 0 | 0 |
| Y/N | 26159 |
Fn3-78 |
72 | None | 0.9664 | None | 1.0 | D | 0.873 | 0.907 | 0.94703877 | gnomAD-4.0.0 | 2.05456E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70046E-06 | 0 | 0 |
| Y/C | 26357 |
Fn3-79 |
72 | rs1461657543 |
0.9929 | -2.146 | 1.0 | D | 0.874 | 0.896 | 0.9290748 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/C | 26357 |
Fn3-79 |
72 | rs1461657543 |
0.9929 | -2.146 | 1.0 | D | 0.874 | 0.896 | 0.9290748 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| Y/C | 26357 |
Fn3-79 |
72 | rs1461657543 |
0.9929 | -2.146 | 1.0 | D | 0.874 | 0.896 | 0.9290748 | gnomAD-4.0.0 | 2.47918E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47731E-07 | 3.29381E-05 | 0 |
| Y/H | 26357 |
Fn3-79 |
72 | None | 0.9983 | None | 1.0 | D | 0.843 | 0.899 | 0.84195626 | gnomAD-4.0.0 | 1.59168E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85923E-06 | 0 | 0 |
| Y/N | 26357 |
Fn3-79 |
72 | rs973899750 |
0.9875 | None | 1.0 | D | 0.875 | 0.902 | 0.9453439 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 26357 |
Fn3-79 |
72 | rs973899750 |
0.9875 | None | 1.0 | D | 0.875 | 0.902 | 0.9453439 | gnomAD-4.0.0 | 2.62957E-05 | None | None | None | None | N | None | 9.65204E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/S | 26753 |
Fn3-82 |
71 | rs1321131877 |
0.9452 | -3.377 | 1.0 | D | 0.874 | 0.838 | 0.9399972 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/S | 26753 |
Fn3-82 |
71 | rs1321131877 |
0.9452 | -3.377 | 1.0 | D | 0.874 | 0.838 | 0.9399972 | gnomAD-4.0.0 | 6.36628E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57756E-06 | 1.43279E-05 | 0 |
| Y/C | 27143 |
Fn3-85 |
72 | rs1288732444 |
0.8104 | None | 1.0 | D | 0.863 | 0.866 | 0.89594537 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| Y/C | 27143 |
Fn3-85 |
72 | rs1288732444 |
0.8104 | None | 1.0 | D | 0.863 | 0.866 | 0.89594537 | gnomAD-4.0.0 | 6.5716E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| Y/H | 27241 |
Fn3-86 |
72 | rs773476805 |
0.96 | -2.588 | 1.0 | D | 0.846 | 0.826 | 0.76532066 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 27241 |
Fn3-86 |
72 | rs773476805 |
0.96 | -2.588 | 1.0 | D | 0.846 | 0.826 | 0.76532066 | gnomAD-4.0.0 | 3.18443E-06 | None | None | None | None | N | None | 0 | 4.57875E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 27440 |
Fn3-87 |
72 | rs781246930 |
0.9863 | -2.344 | 0.999 | D | 0.851 | 0.894 | 0.93382734 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 27440 |
Fn3-87 |
72 | rs781246930 |
0.9863 | -2.344 | 0.999 | D | 0.851 | 0.894 | 0.93382734 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 5.65483E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 27540 |
Fn3-88 |
72 | rs913135593 |
0.6989 | -2.114 | 1.0 | D | 0.857 | 0.802 | 0.8685163 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 27540 |
Fn3-88 |
72 | rs913135593 |
0.6989 | -2.114 | 1.0 | D | 0.857 | 0.802 | 0.8685163 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 27540 |
Fn3-88 |
72 | rs913135593 |
0.6989 | -2.114 | 1.0 | D | 0.857 | 0.802 | 0.8685163 | gnomAD-4.0.0 | 3.84341E-06 | None | None | None | None | N | None | 5.07425E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 27642 |
Fn3-89 |
73 | None | 0.8097 | None | 1.0 | D | 0.875 | 0.914 | 0.9202925 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/C | 27932 |
Fn3-91 |
70 | None | 0.8523 | None | 1.0 | D | 0.875 | 0.846 | 0.9282206 | gnomAD-4.0.0 | 1.37016E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80001E-06 | 0 | 0 |
| Y/H | 27932 |
Fn3-91 |
70 | rs759559839 |
0.9273 | -2.187 | 1.0 | D | 0.84 | 0.857 | 0.8513791 | gnomAD-2.1.1 | 2.85E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.34522E-04 | None | 0 | 0 | 0 |
| Y/H | 27932 |
Fn3-91 |
70 | rs759559839 |
0.9273 | -2.187 | 1.0 | D | 0.84 | 0.857 | 0.8513791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07987E-04 | 0 |
| Y/H | 27932 |
Fn3-91 |
70 | rs759559839 |
0.9273 | -2.187 | 1.0 | D | 0.84 | 0.857 | 0.8513791 | gnomAD-4.0.0 | 8.06849E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43646E-04 | 0 |
| Y/C | 28125 |
Fn3-92 |
71 | rs763653948 |
0.9507 | -2.163 | 1.0 | D | 0.866 | 0.864 | 0.8725865 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/C | 28125 |
Fn3-92 |
71 | rs763653948 |
0.9507 | -2.163 | 1.0 | D | 0.866 | 0.864 | 0.8725865 | gnomAD-4.0.0 | 1.59183E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85887E-06 | 0 | 0 |
| Y/C | 28225 |
Fn3-93 |
72 | rs1703630700 |
0.904 | None | 1.0 | D | 0.876 | 0.918 | 0.8700506 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 28225 |
Fn3-93 |
72 | rs1703630700 |
0.904 | None | 1.0 | D | 0.876 | 0.918 | 0.8700506 | gnomAD-4.0.0 | 6.57125E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47003E-05 | 0 | 0 |
| Y/F | 28323 |
Fn3-94 |
72 | rs1285180382 |
0.2139 | -1.27 | 0.999 | D | 0.749 | 0.882 | 0.8201327 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 2.02946E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/F | 28323 |
Fn3-94 |
72 | rs1285180382 |
0.2139 | -1.27 | 0.999 | D | 0.749 | 0.882 | 0.8201327 | gnomAD-3.1.2 | 1.64286E-04 | None | None | None | None | N | None | 0 | 1.63741E-03 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 28323 |
Fn3-94 |
72 | rs1285180382 |
0.2139 | -1.27 | 0.999 | D | 0.749 | 0.882 | 0.8201327 | gnomAD-4.0.0 | 2.04511E-05 | None | None | None | None | N | None | 0 | 5.33458E-04 | None | 0 | 0 | None | 0 | 0 | 8.47597E-07 | 0 | 0 |
| Y/C | 28521 |
Fn3-95 |
72 | rs1559288658 |
0.9443 | None | 1.0 | D | 0.881 | 0.906 | 0.9334521 | gnomAD-4.0.0 | 2.73773E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.05485E-05 | None | 0 | 0 | 1.79909E-06 | 0 | 0 |
| Y/H | 28621 |
Fn3-96 |
72 | rs751308383 |
0.9712 | -2.82 | 1.0 | D | 0.845 | 0.848 | 0.8532315 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
| Y/H | 28621 |
Fn3-96 |
72 | rs751308383 |
0.9712 | -2.82 | 1.0 | D | 0.845 | 0.848 | 0.8532315 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/H | 28621 |
Fn3-96 |
72 | rs751308383 |
0.9712 | -2.82 | 1.0 | D | 0.845 | 0.848 | 0.8532315 | gnomAD-4.0.0 | 1.36331E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.86472E-05 | 0 | 0 |
| Y/H | 28721 |
Fn3-97 |
71 | rs186625228 |
0.9671 | -2.146 | 1.0 | D | 0.853 | 0.869 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| Y/H | 28721 |
Fn3-97 |
71 | rs186625228 |
0.9671 | -2.146 | 1.0 | D | 0.853 | 0.869 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 28721 |
Fn3-97 |
71 | rs186625228 |
0.9671 | -2.146 | 1.0 | D | 0.853 | 0.869 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| Y/C | 28915 |
Fn3-98 |
71 | rs764006835 |
0.6155 | -1.253 | 1.0 | D | 0.845 | 0.823 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 28915 |
Fn3-98 |
71 | rs764006835 |
0.6155 | -1.253 | 1.0 | D | 0.845 | 0.823 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 28915 |
Fn3-98 |
71 | rs764006835 |
0.6155 | -1.253 | 1.0 | D | 0.845 | 0.823 | None | gnomAD-4.0.0 | 6.57065E-06 | None | None | None | None | N | None | 2.4122E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 29011 |
Fn3-99 |
70 | rs2154156569 |
0.9024 | None | 1.0 | D | 0.857 | 0.875 | 0.77832055 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| Y/F | 29208 |
Fn3-100 |
72 | rs201831707 |
0.2916 | -1.423 | 0.999 | D | 0.749 | 0.907 | None | gnomAD-2.1.1 | 1.99713E-04 | None | None | None | None | N | None | 2.47913E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.82108E-04 | 1.40213E-04 |
| Y/F | 29208 |
Fn3-100 |
72 | rs201831707 |
0.2916 | -1.423 | 0.999 | D | 0.749 | 0.907 | None | gnomAD-3.1.2 | 1.97055E-04 | None | None | None | None | N | None | 1.20563E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 3.67453E-04 | 0 | 0 |
| Y/F | 29208 |
Fn3-100 |
72 | rs201831707 |
0.2916 | -1.423 | 0.999 | D | 0.749 | 0.907 | None | gnomAD-4.0.0 | 4.99419E-04 | None | None | None | None | N | None | 1.06735E-04 | 0 | None | 0 | 0 | None | 0 | 1.64528E-04 | 6.42447E-04 | 1.09801E-05 | 6.0837E-04 |
| Y/H | 29208 |
Fn3-100 |
72 | rs760803535 |
0.9662 | -2.743 | 1.0 | D | 0.815 | 0.904 | 0.7797876 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/H | 29208 |
Fn3-100 |
72 | rs760803535 |
0.9662 | -2.743 | 1.0 | D | 0.815 | 0.904 | 0.7797876 | gnomAD-4.0.0 | 2.73668E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79884E-06 | 1.15964E-05 | 1.65645E-05 |
| Y/C | 29308 |
Fn3-101 |
72 | None | 0.8421 | None | 1.0 | D | 0.874 | 0.908 | 0.8662178 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| Y/N | 29406 |
Fn3-102 |
72 | None | 0.872 | None | 1.0 | D | 0.859 | 0.879 | 0.94782895 | gnomAD-4.0.0 | 6.84211E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65656E-05 |
| Y/C | 29704 |
Fn3-104 |
72 | rs727504503 |
0.7217 | -2.204 | 1.0 | D | 0.879 | 0.924 | 0.8923664 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 29704 |
Fn3-104 |
72 | rs727504503 |
0.7217 | -2.204 | 1.0 | D | 0.879 | 0.924 | 0.8923664 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.3089E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 29704 |
Fn3-104 |
72 | rs727504503 |
0.7217 | -2.204 | 1.0 | D | 0.879 | 0.924 | 0.8923664 | gnomAD-4.0.0 | 4.33887E-06 | None | None | None | None | N | None | 0 | 4.99983E-05 | None | 0 | 0 | None | 0 | 0 | 2.54277E-06 | 0 | 1.60118E-05 |
| Y/D | 29806 |
Fn3-105 |
73 | rs982322225 |
0.9621 | -3.489 | 1.0 | D | 0.883 | 0.928 | 0.9412815 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/D | 29806 |
Fn3-105 |
73 | rs982322225 |
0.9621 | -3.489 | 1.0 | D | 0.883 | 0.928 | 0.9412815 | gnomAD-4.0.0 | 1.59115E-06 | None | None | None | None | N | None | 0 | 2.28634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 30003 |
Fn3-106 |
71 | rs761627535 |
0.9405 | -1.364 | 0.055 | N | 0.724 | 0.355 | 0.2195736 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 2.03063E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| F/L | 30003 |
Fn3-106 |
71 | rs761627535 |
0.9405 | -1.364 | 0.055 | N | 0.724 | 0.355 | 0.2195736 | gnomAD-4.0.0 | 2.0686E-05 | None | None | None | None | N | None | 0 | 2.05818E-04 | None | 0 | 0 | None | 0 | 0 | 1.14319E-05 | 0 | 0 |
| Y/C | 30295 |
Fn3-108 |
72 | rs369202604 |
0.9787 | None | 1.0 | D | 0.886 | 0.916 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 30295 |
Fn3-108 |
72 | rs369202604 |
0.9787 | None | 1.0 | D | 0.886 | 0.916 | None | gnomAD-4.0.0 | 3.04481E-06 | None | None | None | None | N | None | 1.74709E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40985E-06 | 0 | 0 |
| Y/C | 30492 |
Fn3-110 |
71 | rs769678577 |
0.4836 | -1.391 | 0.997 | D | 0.879 | 0.801 | 0.847396 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 8.51E-05 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| Y/C | 30492 |
Fn3-110 |
71 | rs769678577 |
0.4836 | -1.391 | 0.997 | D | 0.879 | 0.801 | 0.847396 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 30492 |
Fn3-110 |
71 | rs769678577 |
0.4836 | -1.391 | 0.997 | D | 0.879 | 0.801 | 0.847396 | gnomAD-4.0.0 | 1.79754E-05 | None | None | None | None | N | None | 0 | 3.33533E-05 | None | 0 | 0 | None | 0 | 0 | 2.28884E-05 | 0 | 0 |
| Y/H | 30690 |
Fn3-111 |
72 | None | 0.9968 | None | 1.0 | D | 0.844 | 0.895 | 0.7433497 | gnomAD-4.0.0 | 1.59131E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77331E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 30791 |
Fn3-112 |
73 | None | 0.8894 | None | 1.0 | D | 0.877 | 0.917 | 0.81083393 | gnomAD-4.0.0 | 1.36837E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79885E-06 | 0 | 0 |
| Y/H | 30791 |
Fn3-112 |
73 | rs760556090 |
0.9725 | -2.631 | 1.0 | D | 0.85 | 0.899 | 0.69978714 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11483E-04 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 30791 |
Fn3-112 |
73 | rs760556090 |
0.9725 | -2.631 | 1.0 | D | 0.85 | 0.899 | 0.69978714 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 30791 |
Fn3-112 |
73 | rs760556090 |
0.9725 | -2.631 | 1.0 | D | 0.85 | 0.899 | 0.69978714 | gnomAD-4.0.0 | 6.57255E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 30892 |
Fn3-113 |
72 | None | 0.9602 | None | 1.0 | D | 0.835 | 0.873 | 0.8440417 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| Y/C | 31182 |
Fn3-115 |
70 | None | 0.8113 | None | 1.0 | D | 0.862 | 0.881 | 0.8507113 | gnomAD-4.0.0 | 1.59109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85802E-06 | 0 | 0 |
| Y/H | 31778 |
Fn3-119 |
71 | rs540043466 |
0.9943 | None | 1.0 | D | 0.833 | 0.872 | 0.78946126 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/N | 31778 |
Fn3-119 |
71 | rs540043466 |
0.9725 | None | 1.0 | D | 0.884 | 0.907 | 0.9230492 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 31778 |
Fn3-119 |
71 | rs540043466 |
0.9725 | None | 1.0 | D | 0.884 | 0.907 | 0.9230492 | gnomAD-4.0.0 | 6.57324E-06 | None | None | None | None | N | None | 2.41336E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 32470 |
Fn3-124 |
72 | None | 0.9556 | None | 1.0 | D | 0.847 | 0.868 | 0.93905556 | gnomAD-4.0.0 | 1.36866E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79909E-06 | 0 | 0 |
| Y/D | 32470 |
Fn3-124 |
72 | rs766707276 |
0.9868 | -3.977 | 1.0 | D | 0.83 | 0.853 | 0.95453537 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/D | 32470 |
Fn3-124 |
72 | rs766707276 |
0.9868 | -3.977 | 1.0 | D | 0.83 | 0.853 | 0.95453537 | gnomAD-4.0.0 | 2.73734E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.5982E-06 | 0 | 0 |
| Y/F | 32470 |
Fn3-124 |
72 | None | 0.2831 | None | 0.999 | D | 0.725 | 0.816 | 0.82454145 | gnomAD-4.0.0 | 6.8433E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99543E-07 | 0 | 0 |
| Y/H | 32470 |
Fn3-124 |
72 | None | 0.9594 | None | 1.0 | D | 0.786 | 0.814 | 0.8642107 | gnomAD-4.0.0 | 6.84334E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99551E-07 | 0 | 0 |
| Y/H | 32570 |
Fn3-125 |
72 | rs529186119 |
0.976 | -2.407 | 1.0 | D | 0.841 | 0.894 | 0.7287981 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| Y/H | 32570 |
Fn3-125 |
72 | rs529186119 |
0.976 | -2.407 | 1.0 | D | 0.841 | 0.894 | 0.7287981 | gnomAD-2.1.1 | 8.44E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.92E-05 | None | 0 | 0 | 0 |
| Y/H | 32570 |
Fn3-125 |
72 | rs529186119 |
0.976 | -2.407 | 1.0 | D | 0.841 | 0.894 | 0.7287981 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| Y/H | 32570 |
Fn3-125 |
72 | rs529186119 |
0.976 | -2.407 | 1.0 | D | 0.841 | 0.894 | 0.7287981 | gnomAD-4.0.0 | 1.86839E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.11707E-05 | 3.21719E-05 |
| Y/C | 32866 |
Fn3-127 |
72 | None | 0.942 | None | 1.0 | D | 0.887 | 0.928 | 0.9287761 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/C | 32968 |
Fn3-128 |
73 | rs1575348383 |
0.9888 | None | 1.0 | D | 0.886 | 0.885 | 0.8714871 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85861E-06 | 0 | 0 |
| Y/C | 33069 |
Fn3-129 |
72 | rs377399232 |
0.9189 | -1.274 | 1.0 | D | 0.855 | 0.905 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| Y/C | 33069 |
Fn3-129 |
72 | rs377399232 |
0.9189 | -1.274 | 1.0 | D | 0.855 | 0.905 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 33069 |
Fn3-129 |
72 | rs377399232 |
0.9189 | -1.274 | 1.0 | D | 0.855 | 0.905 | None | gnomAD-4.0.0 | 6.57065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47007E-05 | 0 | 0 |
| Y/N | 33069 |
Fn3-129 |
72 | rs752578821 |
0.9554 | -3.075 | 0.997 | D | 0.863 | 0.875 | 0.9446834 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/N | 33069 |
Fn3-129 |
72 | rs752578821 |
0.9554 | -3.075 | 0.997 | D | 0.863 | 0.875 | 0.9446834 | gnomAD-4.0.0 | 3.18296E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.8659E-05 | 0 |
| Y/C | 33362 |
Fn3-130 |
73 | rs1378557058 |
0.879 | -1.596 | 1.0 | D | 0.857 | 0.902 | 0.9275619 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/C | 33362 |
Fn3-130 |
73 | rs1378557058 |
0.879 | -1.596 | 1.0 | D | 0.857 | 0.902 | 0.9275619 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| Y/C | 33362 |
Fn3-130 |
73 | rs1378557058 |
0.879 | -1.596 | 1.0 | D | 0.857 | 0.902 | 0.9275619 | gnomAD-4.0.0 | 2.56398E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39423E-06 | 0 | 2.84625E-05 |
| Y/C | 33463 |
Fn3-131 |
72 | rs780864416 |
0.8805 | -1.502 | 1.0 | D | 0.9 | 0.874 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 33463 |
Fn3-131 |
72 | rs780864416 |
0.8805 | -1.502 | 1.0 | D | 0.9 | 0.874 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 33463 |
Fn3-131 |
72 | rs780864416 |
0.8805 | -1.502 | 1.0 | D | 0.9 | 0.874 | None | gnomAD-4.0.0 | 3.84337E-06 | None | None | None | None | N | None | 3.38169E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.393E-06 | 0 | 0 |
| Y/H | 33758 |
Fn3-132 |
70 | None | 0.978 | None | 1.0 | D | 0.848 | 0.894 | 0.73051345 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.