Structural position:
- Domain Type: Fn3
- Aligned Position: 109
- Secondary Structure Element: e
- Secondary Structure Region: β-strand F
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S/N | 15733 |
Fn3-1 |
77 | rs190180127 |
0.5603 | -1.291 | 0.998 | D | 0.702 | 0.244 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79392E-04 | None | 0 | None | 0 | 0 | 0 |
| S/N | 15733 |
Fn3-1 |
77 | rs190180127 |
0.5603 | -1.291 | 0.998 | D | 0.702 | 0.244 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.89408E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 15733 |
Fn3-1 |
77 | rs190180127 |
0.5603 | -1.291 | 0.998 | D | 0.702 | 0.244 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| S/N | 15733 |
Fn3-1 |
77 | rs190180127 |
0.5603 | -1.291 | 0.998 | D | 0.702 | 0.244 | None | gnomAD-4.0.0 | 4.34021E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.56397E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 15733 |
Fn3-1 |
77 | rs190180127 |
0.1927 | -0.733 | 0.98 | N | 0.663 | 0.247 | 0.283761946502 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| S/T | 15733 |
Fn3-1 |
77 | rs190180127 |
0.1927 | -0.733 | 0.98 | N | 0.663 | 0.247 | 0.283761946502 | gnomAD-4.0.0 | 6.84568E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9986E-07 | 0 | 0 |
| S/T | 15935 |
Fn3-3 |
77 | None | 0.123 | None | 0.811 | N | 0.569 | 0.1 | 0.16115917748 | gnomAD-4.0.0 | 6.99974E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.22127E-05 | 0 |
| K/M | 16230 |
Fn3-5 |
76 | None | 0.4481 | None | 1.0 | N | 0.688 | 0.424 | 0.356281029322 | gnomAD-4.0.0 | 1.64772E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9569E-06 | 0 | 0 |
| R/T | 16626 |
Fn3-8 |
76 | rs773007980 |
0.4877 | -1.716 | 0.998 | N | 0.679 | 0.362 | 0.384752662912 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.7E-05 | 5.21E-05 | None | 0 | None | 0 | 0 | 0 |
| R/T | 16626 |
Fn3-8 |
76 | rs773007980 |
0.4877 | -1.716 | 0.998 | N | 0.679 | 0.362 | 0.384752662912 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.95389E-04 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 16626 |
Fn3-8 |
76 | rs773007980 |
0.4877 | -1.716 | 0.998 | N | 0.679 | 0.362 | 0.384752662912 | gnomAD-4.0.0 | 3.84946E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.095E-05 | 4.88926E-05 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 16726 |
Fn3-9 |
76 | None | 0.7966 | None | 1.0 | N | 0.719 | 0.381 | 0.310147130316 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/Q | 16827 |
Fn3-10 |
77 | rs138896856 |
0.3246 | -0.982 | 0.992 | N | 0.661 | 0.278 | None | gnomAD-2.1.1 | 1.57554E-04 | None | None | None | None | N | None | 4.13805E-04 | 1.98424E-04 | None | 0 | 0 | None | 3.27161E-04 | None | 4E-04 | 5.49E-05 | 0 |
| R/Q | 16827 |
Fn3-10 |
77 | rs138896856 |
0.3246 | -0.982 | 0.992 | N | 0.661 | 0.278 | None | gnomAD-3.1.2 | 1.51336E-04 | None | None | None | None | N | None | 1.44809E-04 | 6.56E-05 | 0 | 0 | 0 | None | 4.70898E-04 | 0 | 0 | 2.27743E-03 | 0 |
| R/Q | 16827 |
Fn3-10 |
77 | rs138896856 |
0.3246 | -0.982 | 0.992 | N | 0.661 | 0.278 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/Q | 16827 |
Fn3-10 |
77 | rs138896856 |
0.3246 | -0.982 | 0.992 | N | 0.661 | 0.278 | None | gnomAD-4.0.0 | 1.07257E-04 | None | None | None | None | N | None | 2.53435E-04 | 1.33453E-04 | None | 0 | 2.23584E-05 | None | 6.56147E-04 | 0 | 4.49421E-05 | 4.61417E-04 | 1.28115E-04 |
| R/W | 16827 |
Fn3-10 |
77 | rs727503620 |
0.66 | -0.496 | 1.0 | D | 0.612 | 0.525 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.57E-05 | 0 |
| R/W | 16827 |
Fn3-10 |
77 | rs727503620 |
0.66 | -0.496 | 1.0 | D | 0.612 | 0.525 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/W | 16827 |
Fn3-10 |
77 | rs727503620 |
0.66 | -0.496 | 1.0 | D | 0.612 | 0.525 | None | gnomAD-4.0.0 | 1.30211E-05 | None | None | None | None | N | None | 6.68235E-05 | 0 | None | 0 | 0 | None | 0 | 3.29489E-04 | 7.63163E-06 | 4.39425E-05 | 1.602E-05 |
| R/G | 16929 |
Fn3-11 |
78 | None | 0.7159 | None | 1.0 | D | 0.788 | 0.447 | 0.623381163396 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/T | 16929 |
Fn3-11 |
78 | rs1247385443 |
0.566 | -1.599 | 1.0 | N | 0.779 | 0.382 | 0.586996327016 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66556E-04 |
| R/T | 16929 |
Fn3-11 |
78 | rs1247385443 |
0.566 | -1.599 | 1.0 | N | 0.779 | 0.382 | 0.586996327016 | gnomAD-4.0.0 | 4.77946E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41896E-04 | 2.86134E-06 | 0 | 3.0292E-05 |
| R/Q | 17223 |
Fn3-13 |
77 | rs142395261 |
0.2677 | -1.074 | 0.996 | N | 0.694 | 0.287 | None | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | I | None | 1.65549E-04 | 8.49E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/Q | 17223 |
Fn3-13 |
77 | rs142395261 |
0.2677 | -1.074 | 0.996 | N | 0.694 | 0.287 | None | gnomAD-3.1.2 | 9.21E-05 | None | None | None | None | I | None | 2.65662E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 4.78927E-04 |
| R/Q | 17223 |
Fn3-13 |
77 | rs142395261 |
0.2677 | -1.074 | 0.996 | N | 0.694 | 0.287 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/Q | 17223 |
Fn3-13 |
77 | rs142395261 |
0.2677 | -1.074 | 0.996 | N | 0.694 | 0.287 | None | gnomAD-4.0.0 | 1.79828E-05 | None | None | None | None | I | None | 2.26872E-04 | 3.33589E-05 | None | 0 | 0 | None | 0 | 0 | 6.78493E-06 | 0 | 3.20431E-05 |
| R/K | 17446 |
Fn3-14 |
78 | None | 0.1539 | None | None | N | 0.164 | 0.112 | 0.234412748748 | gnomAD-4.0.0 | 4.10947E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.40011E-06 | 0 | 0 |
| C/R | 17545 |
Fn3-15 |
76 | rs1444767974 |
0.899 | -1.36 | 0.997 | N | 0.863 | 0.375 | 0.650482972218 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14705E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/R | 17545 |
Fn3-15 |
76 | rs1444767974 |
0.899 | -1.36 | 0.997 | N | 0.863 | 0.375 | 0.650482972218 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 17545 |
Fn3-15 |
76 | rs1444767974 |
0.899 | -1.36 | 0.997 | N | 0.863 | 0.375 | 0.650482972218 | gnomAD-4.0.0 | 1.86349E-06 | None | None | None | None | N | None | 1.33754E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.48878E-07 | 1.10571E-05 | 0 |
| S/R | 17645 |
Fn3-16 |
77 | rs763695128 |
0.3401 | -0.748 | 0.055 | N | 0.721 | 0.199 | 0.17258766438 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| S/R | 17645 |
Fn3-16 |
77 | rs763695128 |
0.3401 | -0.748 | 0.055 | N | 0.721 | 0.199 | 0.17258766438 | gnomAD-4.0.0 | 2.73797E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59901E-06 | 0 | 0 |
| I/T | 17838 |
Fn3-17 |
75 | None | 0.2149 | None | 0.001 | N | 0.403 | 0.121 | 0.456919554969 | gnomAD-4.0.0 | 1.59447E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86297E-06 | 0 | 0 |
| I/V | 17838 |
Fn3-17 |
75 | rs1339075657 |
0.0979 | -1.716 | None | N | 0.115 | 0.131 | 0.318828661733 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| I/V | 17838 |
Fn3-17 |
75 | rs1339075657 |
0.0979 | -1.716 | None | N | 0.115 | 0.131 | 0.318828661733 | gnomAD-4.0.0 | 1.59448E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86302E-06 | 0 | 0 |
| K/R | 17938 |
Fn3-18 |
77 | None | 0.0972 | None | 0.006 | N | 0.335 | 0.08 | 0.156986980423 | gnomAD-4.0.0 | 1.59491E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43587E-05 | 0 |
| R/S | 18142 |
Fn3-19 |
78 | rs1455326648 |
0.784 | None | 0.961 | N | 0.622 | 0.324 | 0.210429274316 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/S | 18142 |
Fn3-19 |
78 | rs1455326648 |
0.784 | None | 0.961 | N | 0.622 | 0.324 | 0.210429274316 | gnomAD-4.0.0 | 1.72692E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.09228E-06 | 0 | 0 |
| R/W | 18142 |
Fn3-19 |
78 | None | 0.4871 | None | 1.0 | N | 0.677 | 0.458 | 0.424430313326 | gnomAD-4.0.0 | 1.72857E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.24359E-05 |
| M/I | 18247 |
Fn3-20 |
82 | rs368858337 |
0.7118 | -0.661 | 0.042 | N | 0.668 | 0.197 | 0.359963025489 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| M/I | 18247 |
Fn3-20 |
82 | rs368858337 |
0.7118 | -0.661 | 0.042 | N | 0.668 | 0.197 | 0.359963025489 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/I | 18247 |
Fn3-20 |
82 | rs368858337 |
0.7118 | -0.661 | 0.042 | N | 0.668 | 0.197 | 0.359963025489 | gnomAD-4.0.0 | 1.61261E-05 | None | None | None | None | N | None | 1.73555E-04 | 0 | None | 0 | 0 | None | 0 | 4.96196E-04 | 3.39314E-06 | 1.09941E-05 | 8.01179E-05 |
| M/T | 18247 |
Fn3-20 |
82 | rs200585270 |
0.3449 | -1.839 | 0.042 | N | 0.659 | 0.259 | None | gnomAD-2.1.1 | 2.93098E-04 | None | None | None | None | N | None | 8.28E-05 | 1.24568E-03 | None | 7.75044E-04 | 0 | None | 0 | None | 0 | 1.25113E-04 | 1.68681E-03 |
| M/T | 18247 |
Fn3-20 |
82 | rs200585270 |
0.3449 | -1.839 | 0.042 | N | 0.659 | 0.259 | None | gnomAD-3.1.2 | 1.51348E-04 | None | None | None | None | N | None | 7.24E-05 | 5.90319E-04 | 0 | 5.76369E-04 | 0 | None | 0 | 0 | 1.03056E-04 | 0 | 9.56023E-04 |
| M/T | 18247 |
Fn3-20 |
82 | rs200585270 |
0.3449 | -1.839 | 0.042 | N | 0.659 | 0.259 | None | gnomAD-4.0.0 | 1.27761E-04 | None | None | None | None | N | None | 6.67236E-05 | 9.67344E-04 | None | 8.79686E-04 | 0 | None | 0 | 1.32319E-03 | 7.0407E-05 | 0 | 4.1656E-04 |
| K/E | 18350 |
Fn3-21 |
79 | None | 0.5063 | None | 0.92 | N | 0.751 | 0.233 | 0.26169431596 | gnomAD-4.0.0 | 6.00162E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56252E-06 | 0 | 0 |
| R/Q | 18554 |
Fn3-22 |
76 | rs202126861 |
0.1518 | -0.983 | 0.998 | N | 0.629 | 0.22 | None | gnomAD-2.1.1 | 3.6E-05 | None | None | None | None | N | None | 1.24285E-04 | 2.85E-05 | None | 0 | 1.03918E-04 | None | 0 | None | 4.02E-05 | 2.36E-05 | 0 |
| R/Q | 18554 |
Fn3-22 |
76 | rs202126861 |
0.1518 | -0.983 | 0.998 | N | 0.629 | 0.22 | None | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 1.44907E-04 | 0 | 0 | 0 | 3.89105E-04 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/Q | 18554 |
Fn3-22 |
76 | rs202126861 |
0.1518 | -0.983 | 0.998 | N | 0.629 | 0.22 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| R/Q | 18554 |
Fn3-22 |
76 | rs202126861 |
0.1518 | -0.983 | 0.998 | N | 0.629 | 0.22 | None | gnomAD-4.0.0 | 2.04979E-05 | None | None | None | None | N | None | 1.33547E-04 | 3.34549E-05 | None | 0 | 4.48672E-05 | None | 3.1292E-05 | 0 | 1.18903E-05 | 2.20751E-05 | 1.60442E-05 |
| K/N | 18660 |
Fn3-23 |
82 | rs776347511 |
0.8876 | None | 0.982 | N | 0.62 | 0.333 | 0.18274738541 | gnomAD-4.0.0 | 6.84524E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99818E-07 | 0 | 0 |
| M/T | 18860 |
Fn3-24 |
77 | rs1384923019 |
0.2495 | None | 0.979 | N | 0.685 | 0.33 | 0.643685692495 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/T | 18860 |
Fn3-24 |
77 | rs1384923019 |
0.2495 | None | 0.979 | N | 0.685 | 0.33 | 0.643685692495 | gnomAD-4.0.0 | 2.62433E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62988E-06 | 1.3832E-05 | 0 |
| Y/C | 18964 |
Fn3-25 |
81 | rs770854579 |
0.0963 | -0.934 | 0.993 | N | 0.627 | 0.335 | 0.571034400148 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.54385E-04 | None | 0 | None | 0 | 0 | 0 |
| Y/C | 18964 |
Fn3-25 |
81 | rs770854579 |
0.0963 | -0.934 | 0.993 | N | 0.627 | 0.335 | 0.571034400148 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9425E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 18964 |
Fn3-25 |
81 | rs770854579 |
0.0963 | -0.934 | 0.993 | N | 0.627 | 0.335 | 0.571034400148 | gnomAD-4.0.0 | 2.56372E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.85956E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 18964 |
Fn3-25 |
81 | None | 0.2099 | None | 0.975 | N | 0.623 | 0.259 | 0.387202362727 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/T | 19064 |
Fn3-26 |
77 | rs114405804 |
0.2553 | -1.594 | None | N | None | 0.424 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 19064 |
Fn3-26 |
77 | rs114405804 |
0.2553 | -1.594 | None | N | None | 0.424 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/T | 19064 |
Fn3-26 |
77 | rs114405804 |
0.2553 | -1.594 | None | N | None | 0.424 | None | gnomAD-4.0.0 | 6.57091E-06 | None | None | None | None | N | None | 2.4072E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 19259 |
Fn3-27 |
77 | rs868535712 |
0.7233 | -0.349 | 1.0 | N | 0.647 | 0.4 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.42E-05 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 19259 |
Fn3-27 |
77 | rs868535712 |
0.7233 | -0.349 | 1.0 | N | 0.647 | 0.4 | None | gnomAD-4.0.0 | 2.02777E-05 | None | None | None | None | N | None | 5.3904E-05 | 1.82535E-05 | None | 0 | 0 | None | 0 | 0 | 2.15432E-05 | 0 | 3.26691E-05 |
| S/N | 19360 |
Fn3-28 |
77 | rs761996172 |
0.6997 | -1.446 | 0.999 | N | 0.707 | 0.296 | None | gnomAD-2.1.1 | 8.13E-06 | None | None | None | None | N | None | 6.48E-05 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 19360 |
Fn3-28 |
77 | rs761996172 |
0.6997 | -1.446 | 0.999 | N | 0.707 | 0.296 | None | gnomAD-4.0.0 | 3.20004E-06 | None | None | None | None | N | None | 5.69866E-05 | 2.30287E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 19555 |
Fn3-29 |
77 | None | 0.1776 | None | None | N | 0.236 | 0.195 | 0.0716867268079 | gnomAD-4.0.0 | 1.59301E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43345E-05 | 0 |
| H/Y | 19555 |
Fn3-29 |
77 | rs1289211242 |
0.0812 | 0.178 | None | N | 0.158 | 0.144 | 0.0716867268079 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| H/Y | 19555 |
Fn3-29 |
77 | rs1289211242 |
0.0812 | 0.178 | None | N | 0.158 | 0.144 | 0.0716867268079 | gnomAD-4.0.0 | 6.84543E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9963E-06 | 0 | 0 |
| S/P | 19655 |
Fn3-30 |
77 | None | 0.9887 | None | 0.497 | N | 0.783 | 0.289 | 0.183819452728 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| L/S | 19758 |
Fn3-31 |
79 | None | 0.1814 | None | 0.012 | N | 0.667 | 0.117 | 0.27479166964 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| A/D | 19952 |
Fn3-32 |
76 | rs1314159875 |
0.979 | -2.902 | 1.0 | N | 0.788 | 0.539 | 0.745165706587 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| A/D | 19952 |
Fn3-32 |
76 | rs1314159875 |
0.979 | -2.902 | 1.0 | N | 0.788 | 0.539 | 0.745165706587 | gnomAD-4.0.0 | 1.59291E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86012E-06 | 0 | 0 |
| A/S | 19952 |
Fn3-32 |
76 | rs1037724422 |
0.1829 | None | 1.0 | N | 0.637 | 0.312 | 0.290590437066 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/R | 20051 |
Fn3-33 |
75 | None | 0.1003 | None | 0.001 | N | 0.285 | 0.057 | 0.188950314367 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/I | 20247 |
Fn3-34 |
77 | None | 0.5173 | None | 0.497 | N | 0.697 | 0.221 | 0.274366138417 | gnomAD-4.0.0 | 6.84328E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9962E-07 | 0 | 0 |
| R/K | 20247 |
Fn3-34 |
77 | None | 0.1147 | None | None | N | 0.318 | 0.119 | 0.0401082797425 | gnomAD-4.0.0 | 6.84328E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65678E-05 |
| R/T | 20247 |
Fn3-34 |
77 | rs1476856391 |
0.4302 | -1.473 | 0.124 | N | 0.564 | 0.215 | 0.183819452728 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| R/T | 20247 |
Fn3-34 |
77 | rs1476856391 |
0.4302 | -1.473 | 0.124 | N | 0.564 | 0.215 | 0.183819452728 | gnomAD-4.0.0 | 6.84328E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1595E-05 | 0 |
| F/S | 20346 |
Fn3-35 |
76 | rs2050017310 |
0.4571 | None | 0.971 | N | 0.683 | 0.481 | 0.465549362696 | gnomAD-4.0.0 | 4.77807E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.33936E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 20643 |
Fn3-37 |
75 | None | 0.8166 | None | 0.994 | N | 0.845 | 0.49 | 0.477917065107 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/S | 20643 |
Fn3-37 |
75 | None | 0.3439 | None | 0.489 | N | 0.555 | 0.348 | 0.518752145996 | gnomAD-4.0.0 | 6.843E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| C/Y | 20643 |
Fn3-37 |
75 | rs879181408 |
0.813 | -1.625 | 0.998 | N | 0.817 | 0.381 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 20643 |
Fn3-37 |
75 | rs879181408 |
0.813 | -1.625 | 0.998 | N | 0.817 | 0.381 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 20643 |
Fn3-37 |
75 | rs879181408 |
0.813 | -1.625 | 0.998 | N | 0.817 | 0.381 | None | gnomAD-4.0.0 | 6.19783E-06 | None | None | None | None | N | None | 1.33515E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.62954E-06 | 0 | 0 |
| R/C | 20939 |
Fn3-39 |
76 | rs369694001 |
0.3301 | -1.607 | 1.0 | N | 0.823 | 0.391 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| R/C | 20939 |
Fn3-39 |
76 | rs369694001 |
0.3301 | -1.607 | 1.0 | N | 0.823 | 0.391 | None | gnomAD-4.0.0 | 8.89892E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.16957E-05 | 0 | 0 |
| R/G | 20939 |
Fn3-39 |
76 | rs369694001 |
0.8446 | None | 1.0 | N | 0.774 | 0.434 | 0.442466506703 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/G | 20939 |
Fn3-39 |
76 | rs369694001 |
0.8446 | None | 1.0 | N | 0.774 | 0.434 | 0.442466506703 | gnomAD-4.0.0 | 1.24009E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69568E-06 | 0 | 0 |
| R/H | 20939 |
Fn3-39 |
76 | rs777095470 |
0.3204 | -2.004 | 1.0 | N | 0.856 | 0.467 | 0.440498838766 | gnomAD-2.1.1 | 2.51E-05 | None | None | None | None | N | None | 4.14E-05 | 2.84E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 3.13E-05 | 0 |
| R/H | 20939 |
Fn3-39 |
76 | rs777095470 |
0.3204 | -2.004 | 1.0 | N | 0.856 | 0.467 | 0.440498838766 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| R/H | 20939 |
Fn3-39 |
76 | rs777095470 |
0.3204 | -2.004 | 1.0 | N | 0.856 | 0.467 | 0.440498838766 | gnomAD-4.0.0 | 2.41813E-05 | None | None | None | None | N | None | 2.67187E-05 | 1.66995E-05 | None | 0 | 0 | None | 1.56499E-05 | 0 | 2.79786E-05 | 1.0981E-05 | 1.60215E-05 |
| K/T | 21039 |
Fn3-40 |
77 | rs886038878 |
0.3658 | -1.488 | 0.955 | N | 0.661 | 0.262 | 0.328486982098 | gnomAD-2.1.1 | 8E-06 | None | None | None | None | N | None | 4.21E-05 | 3.39E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/T | 21039 |
Fn3-40 |
77 | rs886038878 |
0.3658 | -1.488 | 0.955 | N | 0.661 | 0.262 | 0.328486982098 | gnomAD-3.1.2 | 9.21E-05 | None | None | None | None | N | None | 9.65E-05 | 5.90164E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| K/T | 21039 |
Fn3-40 |
77 | rs886038878 |
0.3658 | -1.488 | 0.955 | N | 0.661 | 0.262 | 0.328486982098 | gnomAD-4.0.0 | 2.43071E-05 | None | None | None | None | N | None | 6.95894E-05 | 2.47723E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.00481E-05 |
| C/Y | 21146 |
Fn3-41 |
83 | rs373360112 |
0.3638 | -1.355 | 0.975 | N | 0.741 | 0.325 | None | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.7E-05 | 0 |
| C/Y | 21146 |
Fn3-41 |
83 | rs373360112 |
0.3638 | -1.355 | 0.975 | N | 0.741 | 0.325 | None | gnomAD-4.0.0 | 4.11121E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60081E-06 | 0 | 3.31862E-05 |
| T/I | 21341 |
Fn3-42 |
76 | None | 0.174 | None | 0.977 | N | 0.771 | 0.289 | 0.326074293725 | gnomAD-4.0.0 | 1.59221E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| T/S | 21341 |
Fn3-42 |
76 | None | 0.1428 | None | 0.98 | N | 0.727 | 0.255 | 0.245101548738 | gnomAD-4.0.0 | 4.8013E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25002E-06 | 0 | 0 |
| A/T | 21442 |
Fn3-43 |
77 | rs886042279 |
0.1582 | -1.621 | 0.716 | N | 0.59 | 0.221 | 0.426787303895 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65893E-04 |
| A/T | 21442 |
Fn3-43 |
77 | rs886042279 |
0.1582 | -1.621 | 0.716 | N | 0.59 | 0.221 | 0.426787303895 | gnomAD-4.0.0 | 3.18522E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 3.0259E-05 |
| A/V | 21442 |
Fn3-43 |
77 | rs769108408 |
0.2283 | -0.156 | 0.081 | N | 0.36 | 0.081 | None | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| A/V | 21442 |
Fn3-43 |
77 | rs769108408 |
0.2283 | -0.156 | 0.081 | N | 0.36 | 0.081 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/V | 21442 |
Fn3-43 |
77 | rs769108408 |
0.2283 | -0.156 | 0.081 | N | 0.36 | 0.081 | None | gnomAD-4.0.0 | 1.92188E-05 | None | None | None | None | N | None | 4.00727E-05 | 1.66806E-05 | None | 0 | 0 | None | 0 | 0 | 2.03496E-05 | 0 | 4.80523E-05 |
| R/C | 21635 |
Fn3-44 |
77 | rs201614524 |
0.1923 | -1.4 | 1.0 | N | 0.759 | 0.546 | None | gnomAD-2.1.1 | 6.07E-05 | None | None | None | None | I | None | 4.13E-05 | 2.83E-05 | None | 0 | 2.56753E-04 | None | 0 | None | 0 | 7.83E-05 | 0 |
| R/C | 21635 |
Fn3-44 |
77 | rs201614524 |
0.1923 | -1.4 | 1.0 | N | 0.759 | 0.546 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | I | None | 4.83E-05 | 6.55E-05 | 0 | 0 | 3.87898E-04 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/C | 21635 |
Fn3-44 |
77 | rs201614524 |
0.1923 | -1.4 | 1.0 | N | 0.759 | 0.546 | None | gnomAD-4.0.0 | 1.79751E-05 | None | None | None | None | I | None | 6.67699E-05 | 3.33511E-05 | None | 0 | 8.921E-05 | None | 0 | 0 | 1.52597E-05 | 0 | 0 |
| R/H | 21635 |
Fn3-44 |
77 | rs756768598 |
0.1873 | -1.878 | 1.0 | N | 0.838 | 0.438 | 0.328752806141 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | I | None | 1.29232E-04 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| R/H | 21635 |
Fn3-44 |
77 | rs756768598 |
0.1873 | -1.878 | 1.0 | N | 0.838 | 0.438 | 0.328752806141 | gnomAD-4.0.0 | 2.53201E-05 | None | None | None | None | I | None | 2.98989E-05 | 0 | None | 0 | 2.52016E-05 | None | 0 | 1.73551E-04 | 2.42895E-05 | 3.47891E-05 | 6.62866E-05 |
| Y/C | 21735 |
Fn3-45 |
77 | rs1430331721 |
0.1297 | -1.715 | 0.997 | N | 0.674 | 0.376 | 0.542187413537 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| C/S | 22031 |
Fn3-47 |
76 | rs1437140291 |
0.211 | -2.078 | 0.002 | N | 0.388 | 0.261 | 0.424908009808 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.87853E-04 | 0 | 0 |
| C/S | 22031 |
Fn3-47 |
76 | rs1437140291 |
0.211 | -2.078 | 0.002 | N | 0.388 | 0.261 | 0.424908009808 | gnomAD-4.0.0 | 1.5977E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88523E-05 | 0 | 0 | 0 | 0 |
| T/A | 22131 |
Fn3-48 |
77 | rs140842479 |
0.1083 | -1.604 | 0.012 | N | 0.435 | 0.154 | None | gnomAD-2.1.1 | 1.5006E-04 | None | None | None | None | N | None | 1.44688E-03 | 1.69847E-04 | None | 0 | 0 | None | 0 | None | 0 | 7.82E-06 | 0 |
| T/A | 22131 |
Fn3-48 |
77 | rs140842479 |
0.1083 | -1.604 | 0.012 | N | 0.435 | 0.154 | None | gnomAD-3.1.2 | 4.60199E-04 | None | None | None | None | N | None | 1.49549E-03 | 3.27697E-04 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| T/A | 22131 |
Fn3-48 |
77 | rs140842479 |
0.1083 | -1.604 | 0.012 | N | 0.435 | 0.154 | None | 1000 genomes | 1.59744E-03 | None | None | None | None | N | None | 5.3E-03 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/A | 22131 |
Fn3-48 |
77 | rs140842479 |
0.1083 | -1.604 | 0.012 | N | 0.435 | 0.154 | None | gnomAD-4.0.0 | 8.05776E-05 | None | None | None | None | N | None | 1.26653E-03 | 1.83401E-04 | None | 0 | 0 | None | 0 | 1.65344E-04 | 1.18693E-05 | 0 | 1.44106E-04 |
| T/I | 22131 |
Fn3-48 |
77 | rs1553626919 |
0.1098 | None | None | N | 0.441 | 0.119 | 0.188950314367 | gnomAD-4.0.0 | 1.59236E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02682E-05 |
| Y/C | 22233 |
Fn3-49 |
78 | rs763250975 |
0.1014 | -1.433 | None | N | 0.452 | 0.308 | 0.234412748748 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/C | 22233 |
Fn3-49 |
78 | rs763250975 |
0.1014 | -1.433 | None | N | 0.452 | 0.308 | 0.234412748748 | gnomAD-4.0.0 | 3.18792E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72597E-06 | 0 | 0 |
| F/L | 22429 |
Fn3-50 |
76 | rs879180662 |
0.7316 | -1.843 | None | N | 0.194 | 0.284 | 0.260249123532 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| F/L | 22429 |
Fn3-50 |
76 | rs879180662 |
0.7316 | -1.843 | None | N | 0.194 | 0.284 | 0.260249123532 | gnomAD-4.0.0 | 3.18462E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86017E-06 | 0 | 3.02627E-05 |
| S/N | 22524 |
Fn3-51 |
74 | rs397517670 |
0.1965 | -1.478 | 0.024 | N | 0.471 | 0.175 | 0.119812018005 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 3.27E-05 | None | 0 | 1.78E-05 | 1.65948E-04 |
| S/N | 22524 |
Fn3-51 |
74 | rs397517670 |
0.1965 | -1.478 | 0.024 | N | 0.471 | 0.175 | 0.119812018005 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14594E-04 | 0 |
| S/N | 22524 |
Fn3-51 |
74 | rs397517670 |
0.1965 | -1.478 | 0.024 | N | 0.471 | 0.175 | 0.119812018005 | gnomAD-4.0.0 | 2.16952E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23145E-05 | None | 0 | 0 | 1.52603E-05 | 1.53725E-04 | 3.20307E-05 |
| S/G | 22719 |
Fn3-52 |
77 | rs2047057436 |
0.1799 | None | 0.166 | N | 0.637 | 0.215 | 0.18274738541 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93648E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 22719 |
Fn3-52 |
77 | rs2047057436 |
0.1799 | None | 0.166 | N | 0.637 | 0.215 | 0.18274738541 | gnomAD-4.0.0 | 3.04496E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.41142E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 22719 |
Fn3-52 |
77 | rs1291771757 |
0.3238 | -1.291 | 0.491 | N | 0.701 | 0.175 | 0.186928172975 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 22719 |
Fn3-52 |
77 | rs1291771757 |
0.3238 | -1.291 | 0.491 | N | 0.701 | 0.175 | 0.186928172975 | gnomAD-4.0.0 | 3.18495E-06 | None | None | None | None | N | None | 0 | 4.57415E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 22719 |
Fn3-52 |
77 | None | 0.6344 | None | 0.003 | N | 0.631 | 0.296 | 0.208000267992 | gnomAD-4.0.0 | 1.59247E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77701E-05 | None | 0 | 0 | 0 | 0 | 0 |
| M/L | 22819 |
Fn3-53 |
77 | rs878959858 |
0.2526 | None | 0.015 | N | 0.235 | 0.193 | 0.394079506076 | gnomAD-4.0.0 | 1.59252E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86048E-06 | 0 | 0 |
| M/T | 22819 |
Fn3-53 |
77 | rs770698117 |
0.2904 | -2.305 | 0.959 | N | 0.747 | 0.411 | 0.594339124078 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| M/T | 22819 |
Fn3-53 |
77 | rs770698117 |
0.2904 | -2.305 | 0.959 | N | 0.747 | 0.411 | 0.594339124078 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/T | 22819 |
Fn3-53 |
77 | rs770698117 |
0.2904 | -2.305 | 0.959 | N | 0.747 | 0.411 | 0.594339124078 | gnomAD-4.0.0 | 1.05385E-05 | None | None | None | None | N | None | 1.33526E-05 | 0 | None | 0 | 2.23444E-05 | None | 0 | 0 | 1.18698E-05 | 0 | 1.60179E-05 |
| R/K | 22917 |
Fn3-54 |
77 | rs2046750925 |
0.1202 | None | 0.006 | N | 0.317 | 0.131 | 0.143124449307 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 22917 |
Fn3-54 |
77 | rs2046750925 |
0.1202 | None | 0.006 | N | 0.317 | 0.131 | 0.143124449307 | gnomAD-4.0.0 | 6.57497E-06 | None | None | None | None | N | None | 2.41301E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 22917 |
Fn3-54 |
77 | None | 0.4038 | None | 0.822 | N | 0.621 | 0.287 | 0.417586769301 | gnomAD-4.0.0 | 1.59247E-06 | None | None | None | None | N | None | 5.66187E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 23215 |
Fn3-56 |
77 | rs752195064 |
0.3799 | -1.361 | 0.98 | N | 0.753 | 0.272 | 0.252162846088 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 9.28E-05 | 8.91E-06 | 0 |
| S/N | 23215 |
Fn3-56 |
77 | rs752195064 |
0.3799 | -1.361 | 0.98 | N | 0.753 | 0.272 | 0.252162846088 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.41E-05 | 0 | 0 | 0 | 0 |
| S/N | 23215 |
Fn3-56 |
77 | rs752195064 |
0.3799 | -1.361 | 0.98 | N | 0.753 | 0.272 | 0.252162846088 | gnomAD-4.0.0 | 1.28139E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.56873E-04 | 0 | 0 | 0 | 0 |
| S/R | 23317 |
Fn3-57 |
78 | rs1165001201 |
0.4914 | -0.801 | None | N | 0.456 | 0.328 | 0.137902524267 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| S/R | 23317 |
Fn3-57 |
78 | rs1165001201 |
0.4914 | -0.801 | None | N | 0.456 | 0.328 | 0.137902524267 | gnomAD-4.0.0 | 3.18633E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.87026E-05 | 0 |
| M/I | 23510 |
Fn3-58 |
76 | rs727503569 |
0.5823 | None | 0.048 | N | 0.463 | 0.123 | 0.431150418975 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/I | 23510 |
Fn3-58 |
76 | rs727503569 |
0.5823 | None | 0.048 | N | 0.463 | 0.123 | 0.431150418975 | gnomAD-4.0.0 | 3.71861E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08625E-06 | 0 | 0 |
| M/T | 23510 |
Fn3-58 |
76 | None | 0.196 | None | 0.001 | N | 0.381 | 0.269 | 0.469333501611 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/V | 23510 |
Fn3-58 |
76 | None | 0.1996 | None | 0.022 | N | 0.447 | 0.184 | 0.386558576397 | gnomAD-4.0.0 | 1.36852E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79909E-06 | 0 | 0 |
| M/T | 23606 |
Fn3-59 |
75 | rs371030086 |
0.3475 | -2.064 | 0.684 | N | 0.688 | 0.303 | None | gnomAD-2.1.1 | 5E-05 | None | None | None | None | N | None | 4.96032E-04 | 5.66E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/T | 23606 |
Fn3-59 |
75 | rs371030086 |
0.3475 | -2.064 | 0.684 | N | 0.688 | 0.303 | None | gnomAD-3.1.2 | 2.23508E-04 | None | None | None | None | N | None | 7.4825E-04 | 0 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 0 | 0 | 9.56938E-04 |
| M/T | 23606 |
Fn3-59 |
75 | rs371030086 |
0.3475 | -2.064 | 0.684 | N | 0.688 | 0.303 | None | gnomAD-4.0.0 | 3.59464E-05 | None | None | None | None | N | None | 6.53194E-04 | 4.9995E-05 | None | 0 | 0 | None | 0 | 1.65125E-04 | 0 | 0 | 8.00384E-05 |
| K/N | 23802 |
Fn3-60 |
77 | rs1709454274 |
0.8021 | None | 0.83 | D | 0.751 | 0.204 | 0.173771789658 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 23802 |
Fn3-60 |
77 | rs1709454274 |
0.8021 | None | 0.83 | D | 0.751 | 0.204 | 0.173771789658 | gnomAD-4.0.0 | 6.5773E-06 | None | None | None | None | N | None | 2.41394E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 23802 |
Fn3-60 |
77 | rs1168152439 |
0.1913 | None | 0.83 | N | 0.754 | 0.215 | 0.152612264143 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/Q | 23802 |
Fn3-60 |
77 | rs1168152439 |
0.1913 | None | 0.83 | N | 0.754 | 0.215 | 0.152612264143 | gnomAD-4.0.0 | 2.56416E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78925E-06 | 0 | 0 |
| I/T | 23902 |
Fn3-61 |
77 | rs55837610 |
0.0983 | -2.883 | 0.166 | N | 0.698 | 0.275 | None | gnomAD-2.1.1 | 2.16956E-03 | None | None | None | None | N | None | 6.20142E-04 | 1.89683E-03 | None | 4.26191E-03 | 0 | None | 0 | None | 2.80426E-04 | 3.49771E-03 | 3.80175E-03 |
| I/T | 23902 |
Fn3-61 |
77 | rs55837610 |
0.0983 | -2.883 | 0.166 | N | 0.698 | 0.275 | None | gnomAD-3.1.2 | 2.01189E-03 | None | None | None | None | N | None | 7.23973E-04 | 1.11417E-03 | 0 | 4.61361E-03 | 0 | None | 7.53154E-04 | 6.32911E-03 | 3.32353E-03 | 0 | 3.34928E-03 |
| I/T | 23902 |
Fn3-61 |
77 | rs55837610 |
0.0983 | -2.883 | 0.166 | N | 0.698 | 0.275 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 2E-03 | None | None | None | 0 | None |
| I/T | 23902 |
Fn3-61 |
77 | rs55837610 |
0.0983 | -2.883 | 0.166 | N | 0.698 | 0.275 | None | gnomAD-4.0.0 | 2.89115E-03 | None | None | None | None | N | None | 6.66489E-04 | 1.88352E-03 | None | 4.02299E-03 | 0 | None | 6.71938E-04 | 2.31328E-03 | 3.51893E-03 | 1.09823E-05 | 2.78525E-03 |
| I/V | 23902 |
Fn3-61 |
77 | rs1160675688 |
0.069 | -1.961 | 0.001 | N | 0.171 | 0.074 | 0.28492961333 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/V | 23902 |
Fn3-61 |
77 | rs1160675688 |
0.069 | -1.961 | 0.001 | N | 0.171 | 0.074 | 0.28492961333 | gnomAD-4.0.0 | 2.05294E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.47907E-05 | 0 |
| I/S | 24000 |
Fn3-62 |
77 | rs1053083187 |
0.3167 | None | 0.852 | N | 0.739 | 0.293 | 0.591849201417 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/S | 24000 |
Fn3-62 |
77 | rs1053083187 |
0.3167 | None | 0.852 | N | 0.739 | 0.293 | 0.591849201417 | gnomAD-4.0.0 | 6.57376E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47076E-05 | 0 | 0 |
| M/T | 24198 |
Fn3-63 |
77 | None | 0.1868 | None | 0.684 | N | 0.653 | 0.39 | 0.599012661586 | gnomAD-4.0.0 | 1.95311E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.37703E-06 | 0 | 0 |
| M/I | 24298 |
Fn3-64 |
77 | None | 0.3911 | None | 0.003 | N | 0.294 | 0.119 | 0.358948522604 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/I | 25280 |
Fn3-71 |
77 | rs780403765 |
0.5629 | None | 0.002 | N | 0.224 | 0.2 | 0.48512917806 | gnomAD-4.0.0 | 1.43724E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.88913E-05 | 0 | 0 |
| M/V | 25280 |
Fn3-71 |
77 | rs878918988 |
0.1359 | -1.205 | 0.08 | N | 0.478 | 0.205 | 0.474954162714 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| M/V | 25280 |
Fn3-71 |
77 | rs878918988 |
0.1359 | -1.205 | 0.08 | N | 0.478 | 0.205 | 0.474954162714 | gnomAD-4.0.0 | 9.58149E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25942E-05 | 0 | 0 |
| C/Y | 25482 |
Fn3-73 |
78 | None | 0.4161 | None | 0.792 | N | 0.741 | 0.329 | 0.633141044442 | gnomAD-4.0.0 | 2.0538E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.53075E-05 | None | 0 | 0 | 1.79945E-06 | 0 | 0 |
| V/I | 25772 |
Fn3-75 |
75 | None | 0.0786 | None | None | N | 0.181 | 0.045 | 0.240491677333 | gnomAD-4.0.0 | 6.84437E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99604E-07 | 0 | 0 |
| F/L | 25966 |
Fn3-76 |
77 | None | 0.6768 | None | 0.698 | N | 0.726 | 0.189 | 0.350524144436 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| I/M | 26164 |
Fn3-78 |
77 | rs1172977615 |
0.0942 | -2.298 | 0.782 | N | 0.813 | 0.161 | 0.404592120364 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| I/V | 26164 |
Fn3-78 |
77 | rs764140362 |
0.1176 | -2.209 | 0.174 | N | 0.459 | 0.103 | 0.419835214384 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| I/V | 26164 |
Fn3-78 |
77 | rs764140362 |
0.1176 | -2.209 | 0.174 | N | 0.459 | 0.103 | 0.419835214384 | gnomAD-4.0.0 | 3.18976E-06 | None | None | None | None | N | None | 0 | 2.29085E-05 | None | 0 | 0 | None | 0 | 0 | 2.86569E-06 | 0 | 0 |
| M/T | 26362 |
Fn3-79 |
77 | rs529839486 |
0.1673 | -2.226 | 0.684 | N | 0.737 | 0.409 | None | gnomAD-2.1.1 | 2.28689E-04 | None | None | None | None | N | None | 4.13E-05 | 1.41387E-03 | None | 0 | 0 | None | 0 | None | 0 | 7.83E-05 | 4.21704E-04 |
| M/T | 26362 |
Fn3-79 |
77 | rs529839486 |
0.1673 | -2.226 | 0.684 | N | 0.737 | 0.409 | None | gnomAD-3.1.2 | 2.82642E-04 | None | None | None | None | N | None | 1.20633E-04 | 1.7038E-03 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 3.82044E-03 |
| M/T | 26362 |
Fn3-79 |
77 | rs529839486 |
0.1673 | -2.226 | 0.684 | N | 0.737 | 0.409 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| M/T | 26362 |
Fn3-79 |
77 | rs529839486 |
0.1673 | -2.226 | 0.684 | N | 0.737 | 0.409 | None | gnomAD-4.0.0 | 1.59265E-04 | None | None | None | None | N | None | 9.3306E-05 | 1.46667E-03 | None | 3.37861E-05 | 0 | None | 1.56191E-05 | 1.65017E-04 | 1.09354E-04 | 0 | 4.80307E-04 |
| S/P | 26462 |
Fn3-80 |
77 | None | 0.9892 | None | 0.983 | N | 0.717 | 0.468 | 0.386721274199 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/I | 26758 |
Fn3-82 |
76 | rs1705634558 |
0.628 | None | 0.309 | N | 0.699 | 0.18 | 0.359557344763 | gnomAD-4.0.0 | 1.59159E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85919E-06 | 0 | 0 |
| M/R | 26758 |
Fn3-82 |
76 | None | 0.3814 | None | 0.939 | N | 0.681 | 0.531 | 0.524946584802 | gnomAD-4.0.0 | 1.59158E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| M/T | 26758 |
Fn3-82 |
76 | None | 0.2145 | None | 0.684 | N | 0.672 | 0.413 | 0.668175505125 | gnomAD-4.0.0 | 7.95788E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77331E-05 | None | 0 | 0 | 1.14365E-05 | 0 | 0 |
| M/V | 26758 |
Fn3-82 |
76 | None | 0.2013 | None | 0.309 | N | 0.547 | 0.203 | 0.359963025489 | gnomAD-4.0.0 | 3.42133E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49779E-06 | 0 | 0 |
| K/E | 26854 |
Fn3-83 |
75 | None | 0.2641 | None | 0.302 | N | 0.481 | 0.238 | 0.239901079897 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 26854 |
Fn3-83 |
75 | None | 0.489 | None | 0.512 | N | 0.546 | 0.157 | 0.0551355673512 | gnomAD-4.0.0 | 1.59163E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8592E-06 | 0 | 0 |
| F/L | 27048 |
Fn3-84 |
77 | None | 0.6931 | None | 0.005 | N | 0.431 | 0.136 | 0.357519025918 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| F/S | 27048 |
Fn3-84 |
77 | None | 0.1624 | None | None | N | 0.5 | 0.14 | 0.261217442401 | gnomAD-4.0.0 | 1.59558E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8638E-06 | 0 | 0 |
| S/A | 27148 |
Fn3-85 |
77 | None | 0.0941 | None | 0.148 | N | 0.432 | 0.202 | 0.119812018005 | gnomAD-4.0.0 | 6.8437E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99546E-07 | 0 | 0 |
| S/P | 27148 |
Fn3-85 |
77 | rs1705027255 |
0.9878 | None | 0.954 | N | 0.726 | 0.378 | 0.269558022972 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 27148 |
Fn3-85 |
77 | rs1705027255 |
0.9878 | None | 0.954 | N | 0.726 | 0.378 | 0.269558022972 | gnomAD-4.0.0 | 1.23967E-06 | None | None | None | None | N | None | 2.66973E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 27246 |
Fn3-86 |
77 | rs367603381 |
0.2228 | -2.785 | 0.983 | N | 0.737 | 0.343 | None | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 1.24069E-04 | 8.51E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 1.40964E-04 |
| I/T | 27246 |
Fn3-86 |
77 | rs367603381 |
0.2228 | -2.785 | 0.983 | N | 0.737 | 0.343 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.41E-05 | 1.31096E-04 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/T | 27246 |
Fn3-86 |
77 | rs367603381 |
0.2228 | -2.785 | 0.983 | N | 0.737 | 0.343 | None | gnomAD-4.0.0 | 2.04534E-05 | None | None | None | None | N | None | 6.67521E-05 | 1.1678E-04 | None | 0 | 2.23434E-05 | None | 1.56328E-05 | 0 | 1.52577E-05 | 0 | 1.60143E-05 |
| I/V | 27246 |
Fn3-86 |
77 | None | 0.1145 | None | 0.598 | N | 0.492 | 0.116 | 0.451692371253 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/T | 27445 |
Fn3-87 |
77 | None | 0.2032 | None | 0.002 | N | 0.383 | 0.284 | 0.503248607038 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| A/T | 27545 |
Fn3-88 |
77 | rs770320388 |
0.0819 | -1.689 | 0.09 | N | 0.68 | 0.055 | 0.19670166235 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| A/T | 27545 |
Fn3-88 |
77 | rs770320388 |
0.0819 | -1.689 | 0.09 | N | 0.68 | 0.055 | 0.19670166235 | gnomAD-4.0.0 | 1.59126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85827E-06 | 0 | 0 |
| C/Y | 27647 |
Fn3-89 |
78 | rs758578228 |
0.3616 | -1.399 | 1.0 | N | 0.869 | 0.468 | 0.656646541394 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| C/Y | 27647 |
Fn3-89 |
78 | rs758578228 |
0.3616 | -1.399 | 1.0 | N | 0.869 | 0.468 | 0.656646541394 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| C/R | 28130 |
Fn3-92 |
76 | None | 0.4924 | None | 0.003 | N | 0.607 | 0.249 | 0.474010150167 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/W | 28130 |
Fn3-92 |
76 | None | 0.5875 | None | 0.987 | N | 0.717 | 0.309 | 0.464270400615 | gnomAD-4.0.0 | 6.84538E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9976E-07 | 0 | 0 |
| F/L | 28328 |
Fn3-94 |
77 | rs1703507521 |
0.6739 | None | None | N | 0.235 | 0.269 | 0.276482976112 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 28626 |
Fn3-96 |
77 | None | 0.0556 | None | None | N | 0.237 | 0.106 | 0.143124449307 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/H | 28626 |
Fn3-96 |
77 | rs1477861188 |
0.1653 | -2.102 | 0.741 | N | 0.689 | 0.227 | 0.370240404367 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 28626 |
Fn3-96 |
77 | rs1477861188 |
0.1653 | -2.102 | 0.741 | N | 0.689 | 0.227 | 0.370240404367 | gnomAD-4.0.0 | 1.59119E-06 | None | None | None | None | N | None | 0 | 2.28624E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 28920 |
Fn3-98 |
76 | rs1396089552 |
0.0726 | -0.935 | 0.004 | N | 0.615 | 0.134 | 0.193865811164 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/C | 28920 |
Fn3-98 |
76 | rs1396089552 |
0.0726 | -0.935 | 0.004 | N | 0.615 | 0.134 | 0.193865811164 | gnomAD-4.0.0 | 1.59267E-06 | None | None | None | None | N | None | 0 | 2.28843E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 29213 |
Fn3-100 |
77 | rs1001957031 |
0.9335 | -2.238 | 0.998 | N | 0.691 | 0.321 | 0.297031009988 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 1.13186E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/N | 29213 |
Fn3-100 |
77 | rs1001957031 |
0.9335 | -2.238 | 0.998 | N | 0.691 | 0.321 | 0.297031009988 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 29213 |
Fn3-100 |
77 | rs1001957031 |
0.9335 | -2.238 | 0.998 | N | 0.691 | 0.321 | 0.297031009988 | gnomAD-4.0.0 | 2.47861E-06 | None | None | None | None | N | None | 0 | 6.66756E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 29213 |
Fn3-100 |
77 | rs780358002 |
0.0796 | -1.667 | 0.217 | N | 0.333 | 0.125 | 0.291694819147 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| K/R | 29213 |
Fn3-100 |
77 | rs780358002 |
0.0796 | -1.667 | 0.217 | N | 0.333 | 0.125 | 0.291694819147 | gnomAD-4.0.0 | 6.8417E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15955E-05 | 0 |
| K/T | 29213 |
Fn3-100 |
77 | rs780358002 |
0.5524 | None | 0.998 | N | 0.707 | 0.359 | 0.326074293725 | gnomAD-4.0.0 | 2.05251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69826E-06 | 0 | 0 |
| Y/F | 29313 |
Fn3-101 |
77 | None | 0.0616 | None | 0.211 | N | 0.653 | 0.082 | 0.289098819767 | gnomAD-4.0.0 | 6.84166E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| F/L | 29411 |
Fn3-102 |
77 | rs1701736067 |
0.7171 | None | 0.001 | N | 0.228 | 0.255 | 0.234412748748 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 29411 |
Fn3-102 |
77 | rs1701736067 |
0.7171 | None | 0.001 | N | 0.228 | 0.255 | 0.234412748748 | gnomAD-4.0.0 | 6.57056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46998E-05 | 0 | 0 |
| F/Y | 29411 |
Fn3-102 |
77 | rs1433228812 |
0.1899 | -1.376 | 0.662 | N | 0.583 | 0.157 | 0.454145904683 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| F/Y | 29411 |
Fn3-102 |
77 | rs1433228812 |
0.1899 | -1.376 | 0.662 | N | 0.583 | 0.157 | 0.454145904683 | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77886E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 29609 |
Fn3-103 |
77 | rs766450773 |
0.4845 | -2.323 | 1.0 | N | 0.755 | 0.41 | 0.42069145522 | gnomAD-4.0.0 | 6.84818E-06 | None | None | None | None | N | None | 0 | 2.248E-05 | None | 0 | 2.28334E-04 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 29609 |
Fn3-103 |
77 | rs758876816 |
0.1321 | -1.109 | 1.0 | N | 0.795 | 0.321 | 0.270889551736 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63559E-04 | None | 0 | 8.94E-06 | 0 |
| R/Q | 29609 |
Fn3-103 |
77 | rs758876816 |
0.1321 | -1.109 | 1.0 | N | 0.795 | 0.321 | 0.270889551736 | gnomAD-4.0.0 | 1.09493E-05 | None | None | None | None | N | None | 0 | 0 | None | 3.82702E-05 | 2.52793E-05 | None | 0 | 0 | 3.59795E-06 | 1.04362E-04 | 1.65744E-05 |
| C/Y | 29709 |
Fn3-104 |
77 | None | 0.5478 | None | 0.963 | N | 0.743 | 0.306 | 0.715593384032 | gnomAD-4.0.0 | 1.59369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85858E-06 | 0 | 0 |
| R/S | 30300 |
Fn3-108 |
77 | rs770641872 |
0.548 | -1.921 | 0.698 | N | 0.638 | 0.295 | 0.0551355673512 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| R/S | 30300 |
Fn3-108 |
77 | rs770641872 |
0.548 | -1.921 | 0.698 | N | 0.638 | 0.295 | 0.0551355673512 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/S | 30300 |
Fn3-108 |
77 | rs770641872 |
0.548 | -1.921 | 0.698 | N | 0.638 | 0.295 | 0.0551355673512 | gnomAD-4.0.0 | 9.30661E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.27307E-05 | 0 | 0 |
| Y/C | 30400 |
Fn3-109 |
77 | rs376494747 |
0.0833 | -1.957 | 0.001 | N | 0.643 | 0.293 | None | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.89E-06 | 0 |
| Y/C | 30400 |
Fn3-109 |
77 | rs376494747 |
0.0833 | -1.957 | 0.001 | N | 0.643 | 0.293 | None | gnomAD-4.0.0 | 1.36887E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99713E-07 | 1.16015E-05 | 0 |
| Y/F | 30400 |
Fn3-109 |
77 | rs376494747 |
0.0585 | -1.663 | None | N | 0.307 | 0.063 | 0.170165803431 | gnomAD-2.1.1 | 7.25E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 1.49432E-03 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/F | 30400 |
Fn3-109 |
77 | rs376494747 |
0.0585 | -1.663 | None | N | 0.307 | 0.063 | 0.170165803431 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88018E-04 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/F | 30400 |
Fn3-109 |
77 | rs376494747 |
0.0585 | -1.663 | None | N | 0.307 | 0.063 | 0.170165803431 | gnomAD-4.0.0 | 4.52495E-05 | None | None | None | None | N | None | 0 | 1.66795E-05 | None | 1.14919E-03 | 0 | None | 0 | 1.64528E-04 | 1.94998E-05 | 2.19698E-05 | 1.92184E-04 |
| Y/H | 30400 |
Fn3-109 |
77 | rs753682966 |
0.164 | None | 0.484 | N | 0.694 | 0.308 | 0.353974658523 | gnomAD-4.0.0 | 6.84418E-07 | None | None | None | None | N | None | 2.99079E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 30400 |
Fn3-109 |
77 | rs753682966 |
0.244 | -3.142 | 0.741 | N | 0.697 | 0.383 | 0.672318618897 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/N | 30400 |
Fn3-109 |
77 | rs753682966 |
0.244 | -3.142 | 0.741 | N | 0.697 | 0.383 | 0.672318618897 | gnomAD-4.0.0 | 2.05325E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69906E-06 | 0 | 0 |
| I/V | 30497 |
Fn3-110 |
76 | None | 0.1011 | None | 0.19 | N | 0.42 | 0.05 | 0.519133540473 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/P | 30695 |
Fn3-111 |
77 | rs768267695 |
0.9895 | -0.424 | 1.0 | N | 0.797 | 0.52 | 0.423119698836 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| S/P | 30695 |
Fn3-111 |
77 | rs768267695 |
0.9895 | -0.424 | 1.0 | N | 0.797 | 0.52 | 0.423119698836 | gnomAD-4.0.0 | 1.59134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8585E-06 | 0 | 0 |
| M/I | 30796 |
Fn3-112 |
78 | rs1698372447 |
0.5449 | None | 0.454 | N | 0.745 | 0.203 | 0.488827753106 | gnomAD-4.0.0 | 4.77336E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.32131E-05 | None | 0 | 0 | 0 | 0 | 0 |
| M/V | 30796 |
Fn3-112 |
78 | rs773266486 |
0.1638 | -1.491 | 0.454 | N | 0.599 | 0.192 | 0.480801007081 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| S/G | 30897 |
Fn3-113 |
77 | None | 0.128 | None | 0.989 | N | 0.634 | 0.331 | 0.257292322809 | gnomAD-4.0.0 | 1.59107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| S/F | 31091 |
Fn3-114 |
76 | None | 0.2199 | None | 0.001 | N | 0.671 | 0.275 | 0.400613892164 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 31187 |
Fn3-115 |
75 | rs1166582202 |
0.8769 | None | 0.982 | N | 0.715 | 0.147 | 0.162503812791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/N | 31187 |
Fn3-115 |
75 | rs1166582202 |
0.8769 | None | 0.982 | N | 0.715 | 0.147 | 0.162503812791 | gnomAD-4.0.0 | 6.57514E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47029E-05 | 0 | 0 |
| S/G | 31384 |
Fn3-116 |
77 | rs369254232 |
0.2016 | -3.168 | 0.549 | N | 0.693 | 0.219 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/G | 31384 |
Fn3-116 |
77 | rs369254232 |
0.2016 | -3.168 | 0.549 | N | 0.693 | 0.219 | None | gnomAD-4.0.0 | 1.86045E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54415E-06 | 0 | 0 |
| L/S | 31585 |
Fn3-118 |
80 | None | 0.5564 | None | 0.994 | N | 0.723 | 0.474 | 0.756187549339 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| R/T | 31783 |
Fn3-119 |
76 | rs1696869417 |
0.3845 | None | 0.638 | N | 0.667 | 0.348 | 0.311387274539 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 31783 |
Fn3-119 |
76 | rs1696869417 |
0.3845 | None | 0.638 | N | 0.667 | 0.348 | 0.311387274539 | gnomAD-4.0.0 | 2.02984E-06 | None | None | None | None | N | None | 1.74709E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.2049E-06 | 0 | 0 |
| T/I | 31884 |
Fn3-120 |
78 | rs977811552 |
0.2668 | -0.133 | 0.211 | N | 0.564 | 0.209 | 0.329020015101 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 31884 |
Fn3-120 |
78 | rs977811552 |
0.2668 | -0.133 | 0.211 | N | 0.564 | 0.209 | 0.329020015101 | gnomAD-4.0.0 | 6.38457E-06 | None | None | None | None | N | None | 0 | 6.86625E-05 | None | 0 | 0 | None | 0 | 0 | 2.87127E-06 | 0 | 0 |
| A/V | 31986 |
Fn3-121 |
78 | None | 0.3661 | None | 1.0 | N | 0.652 | 0.419 | 0.497679007273 | gnomAD-4.0.0 | 1.59134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85861E-06 | 0 | 0 |
| R/G | 32278 |
Fn3-123 |
77 | None | 0.4204 | None | 1.0 | N | 0.802 | 0.563 | 0.609541433255 | gnomAD-4.0.0 | 1.36931E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80024E-06 | 0 | 0 |
| R/S | 32278 |
Fn3-123 |
77 | rs558927011 |
0.5597 | -1.751 | 1.0 | N | 0.775 | 0.419 | 0.321108458156 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
| R/S | 32278 |
Fn3-123 |
77 | rs558927011 |
0.5597 | -1.751 | 1.0 | N | 0.775 | 0.419 | 0.321108458156 | gnomAD-4.0.0 | 6.84784E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65788E-05 |
| A/T | 32475 |
Fn3-124 |
77 | rs1347342208 |
0.6828 | None | 1.0 | N | 0.742 | 0.351 | 0.322510055762 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 32475 |
Fn3-124 |
77 | rs1347342208 |
0.6828 | None | 1.0 | N | 0.742 | 0.351 | 0.322510055762 | gnomAD-4.0.0 | 3.0451E-06 | None | None | None | None | N | None | 1.74837E-05 | 0 | None | 0 | 1.13585E-04 | None | 0 | 0 | 1.20494E-06 | 0 | 0 |
| T/P | 32575 |
Fn3-125 |
77 | rs746628377 |
0.8935 | -1.164 | 1.0 | N | 0.803 | 0.559 | None | gnomAD-4.0.0 | 5.92665E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.80404E-04 | 0 | 0 | 0 | 3.10328E-05 |
| L/I | 32676 |
Fn3-126 |
77 | None | 0.0987 | None | 0.013 | N | 0.489 | 0.081 | 0.33835085245 | gnomAD-4.0.0 | 1.36894E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31949E-05 | 0 |
| I/S | 32973 |
Fn3-128 |
78 | None | 0.4109 | None | 0.891 | N | 0.725 | 0.375 | 0.704728438482 | gnomAD-4.0.0 | 1.59141E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88239E-05 | 0 | 0 | 0 | 0 |
| I/V | 32973 |
Fn3-128 |
78 | rs773080115 |
0.0968 | -1.806 | 0.002 | N | 0.244 | 0.07 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 32973 |
Fn3-128 |
78 | rs773080115 |
0.0968 | -1.806 | 0.002 | N | 0.244 | 0.07 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 32973 |
Fn3-128 |
78 | rs773080115 |
0.0968 | -1.806 | 0.002 | N | 0.244 | 0.07 | None | gnomAD-4.0.0 | 3.09852E-06 | None | None | None | None | N | None | 5.33903E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47646E-07 | 0 | 0 |
| F/L | 33074 |
Fn3-129 |
77 | rs1692851858 |
0.8299 | None | 0.454 | N | 0.735 | 0.18 | 0.366277470483 | gnomAD-4.0.0 | 1.59164E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 33074 |
Fn3-129 |
77 | rs1328730203 |
0.573 | None | 0.051 | N | 0.53 | 0.295 | 0.512942373286 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 33074 |
Fn3-129 |
77 | rs1328730203 |
0.573 | None | 0.051 | N | 0.53 | 0.295 | 0.512942373286 | gnomAD-4.0.0 | 2.47887E-06 | None | None | None | None | N | None | 5.33974E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 33468 |
Fn3-131 |
77 | rs879250663 |
0.8989 | None | 1.0 | N | 0.735 | 0.429 | 0.224531998449 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/N | 33468 |
Fn3-131 |
77 | rs879250663 |
0.8989 | None | 1.0 | N | 0.735 | 0.429 | 0.224531998449 | gnomAD-4.0.0 | 6.5697E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47003E-05 | 0 | 0 |
| I/T | 33763 |
Fn3-132 |
75 | rs1180167121 |
0.3476 | -2.965 | 0.992 | N | 0.753 | 0.459 | 0.658352620329 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| I/T | 33763 |
Fn3-132 |
75 | rs1180167121 |
0.3476 | -2.965 | 0.992 | N | 0.753 | 0.459 | 0.658352620329 | gnomAD-4.0.0 | 6.8418E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51902E-05 | None | 0 | 0 | 8.09485E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.