Structural position:
- Domain Type: Fn3
- Aligned Position: 121
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V/A | 15744 |
Fn3-1 |
88 | rs1280526830 |
0.1832 | -1.932 | 0.046 | N | 0.383 | 0.147 | 0.397391247328 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 1.54448E-04 | None | 0 | None | 0 | 0 | 0 |
| V/A | 15744 |
Fn3-1 |
88 | rs1280526830 |
0.1832 | -1.932 | 0.046 | N | 0.383 | 0.147 | 0.397391247328 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94628E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 15744 |
Fn3-1 |
88 | rs1280526830 |
0.1832 | -1.932 | 0.046 | N | 0.383 | 0.147 | 0.397391247328 | gnomAD-4.0.0 | 6.41392E-06 | None | None | None | None | N | None | 0 | 1.69676E-05 | None | 0 | 9.72148E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/G | 15744 |
Fn3-1 |
88 | rs1280526830 |
0.3705 | -2.445 | 0.964 | N | 0.717 | 0.323 | 0.793723814882 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/G | 15744 |
Fn3-1 |
88 | rs1280526830 |
0.3705 | -2.445 | 0.964 | N | 0.717 | 0.323 | 0.793723814882 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/G | 15744 |
Fn3-1 |
88 | rs1280526830 |
0.3705 | -2.445 | 0.964 | N | 0.717 | 0.323 | 0.793723814882 | gnomAD-4.0.0 | 6.58224E-06 | None | None | None | None | N | None | 2.41464E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 15845 |
Fn3-2 |
88 | None | 0.9477 | None | 0.999 | D | 0.895 | 0.622 | 0.459370960843 | gnomAD-4.0.0 | 1.36944E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79995E-06 | 0 | 0 |
| S/P | 15946 |
Fn3-3 |
88 | rs369663023 |
0.922 | -0.124 | 0.896 | D | 0.791 | 0.555 | None | gnomAD-2.1.1 | 2.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.76E-05 | 0 |
| S/P | 15946 |
Fn3-3 |
88 | rs369663023 |
0.922 | -0.124 | 0.896 | D | 0.791 | 0.555 | None | gnomAD-3.1.2 | 8.56E-05 | None | None | None | None | N | None | 0 | 0 | 1.20614E-02 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| S/P | 15946 |
Fn3-3 |
88 | rs369663023 |
0.922 | -0.124 | 0.896 | D | 0.791 | 0.555 | None | gnomAD-4.0.0 | 2.11702E-05 | None | None | None | None | N | None | 1.3403E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.78565E-05 | 0 | 1.60823E-05 |
| A/V | 16141 |
Fn3-4 |
87 | None | 0.1743 | None | 0.998 | N | 0.68 | 0.339 | 0.475192790171 | gnomAD-4.0.0 | 2.7388E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60022E-06 | 0 | 0 |
| S/N | 16241 |
Fn3-5 |
87 | None | 0.8995 | None | 0.211 | D | 0.783 | 0.406 | 0.315314060047 | gnomAD-4.0.0 | 2.1041E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.7463E-06 | 0 | 0 |
| V/D | 16437 |
Fn3-6 |
87 | rs767768313 |
0.6948 | -2.163 | 0.93 | N | 0.721 | 0.238 | None | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.93E-05 | 1.41203E-04 |
| V/D | 16437 |
Fn3-6 |
87 | rs767768313 |
0.6948 | -2.163 | 0.93 | N | 0.721 | 0.238 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 4.78469E-04 |
| V/D | 16437 |
Fn3-6 |
87 | rs767768313 |
0.6948 | -2.163 | 0.93 | N | 0.721 | 0.238 | None | gnomAD-4.0.0 | 3.03893E-05 | None | None | None | None | N | None | 1.33651E-05 | 0 | None | 0 | 0 | None | 1.56333E-05 | 0 | 3.9008E-05 | 0 | 1.60313E-05 |
| S/C | 16637 |
Fn3-8 |
87 | None | 0.5693 | None | 1.0 | D | 0.806 | 0.676 | 0.715176864814 | gnomAD-4.0.0 | 1.59437E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4346E-05 | 0 |
| S/N | 16637 |
Fn3-8 |
87 | rs181141442 |
0.9532 | None | 0.994 | D | 0.847 | 0.471 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| S/N | 16637 |
Fn3-8 |
87 | rs181141442 |
0.9532 | None | 0.994 | D | 0.847 | 0.471 | None | gnomAD-4.0.0 | 1.2405E-06 | None | None | None | None | N | None | 0 | 1.67029E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60308E-05 |
| T/A | 16737 |
Fn3-9 |
87 | None | 0.086 | None | 0.005 | N | 0.365 | 0.111 | 0.110078149338 | gnomAD-4.0.0 | 1.59394E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86246E-06 | 0 | 0 |
| T/I | 16737 |
Fn3-9 |
87 | None | 0.2203 | None | 0.012 | N | 0.515 | 0.106 | 0.234412748748 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.93751E-06 | 0 | 0 |
| S/G | 16838 |
Fn3-10 |
88 | rs781528949 |
0.4907 | -1.16 | 0.002 | D | 0.523 | 0.33 | 0.238705975628 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| S/G | 16838 |
Fn3-10 |
88 | rs781528949 |
0.4907 | -1.16 | 0.002 | D | 0.523 | 0.33 | 0.238705975628 | gnomAD-4.0.0 | 3.18678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.42014E-04 | 0 | 1.43542E-05 | 0 |
| S/N | 16838 |
Fn3-10 |
88 | rs755391418 |
0.9356 | None | 0.645 | D | 0.855 | 0.533 | 0.442567846599 | gnomAD-4.0.0 | 6.84615E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65782E-05 |
| S/T | 16838 |
Fn3-10 |
88 | rs755391418 |
0.4058 | -0.888 | 0.645 | D | 0.828 | 0.526 | 0.397540356873 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| S/T | 16838 |
Fn3-10 |
88 | rs755391418 |
0.4058 | -0.888 | 0.645 | D | 0.828 | 0.526 | 0.397540356873 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/T | 16838 |
Fn3-10 |
88 | rs755391418 |
0.4058 | -0.888 | 0.645 | D | 0.828 | 0.526 | 0.397540356873 | gnomAD-4.0.0 | 4.34051E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93594E-06 | 0 | 0 |
| S/P | 16940 |
Fn3-11 |
89 | None | 0.9748 | None | 1.0 | D | 0.884 | 0.756 | 0.589372124375 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/T | 17133 |
Fn3-12 |
87 | rs373628708 |
0.062 | None | 0.651 | N | 0.687 | 0.183 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 17133 |
Fn3-12 |
87 | rs373628708 |
0.062 | None | 0.651 | N | 0.687 | 0.183 | None | gnomAD-4.0.0 | 2.48012E-06 | None | None | None | None | N | None | 1.33579E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54383E-06 | 0 | 0 |
| I/V | 17133 |
Fn3-12 |
87 | None | 0.0621 | None | 0.01 | N | 0.153 | 0.065 | 0.362160248664 | gnomAD-4.0.0 | 1.59313E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78443E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 17234 |
Fn3-13 |
88 | None | 0.4297 | None | 0.863 | N | 0.819 | 0.436 | 0.256793551483 | gnomAD-4.0.0 | 3.20818E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.88401E-05 | 0 |
| S/Y | 17234 |
Fn3-13 |
88 | rs768996750 |
0.9849 | -0.566 | 0.997 | D | 0.905 | 0.631 | 0.812414231654 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 17457 |
Fn3-14 |
89 | rs368055091 |
0.6729 | None | 0.999 | D | 0.897 | 0.4 | 0.663445045466 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| S/N | 17556 |
Fn3-15 |
87 | rs750715335 |
0.9884 | -1.183 | 0.999 | D | 0.899 | 0.572 | 0.485348376517 | gnomAD-2.1.1 | 1.25E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.46E-05 | None | 0 | 1.83E-05 | 0 |
| S/N | 17556 |
Fn3-15 |
87 | rs750715335 |
0.9884 | -1.183 | 0.999 | D | 0.899 | 0.572 | 0.485348376517 | gnomAD-4.0.0 | 1.03277E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.26482E-05 | 1.17791E-05 | 0 |
| G/R | 17656 |
Fn3-16 |
88 | rs1269389543 |
0.8004 | None | 1.0 | N | 0.813 | 0.435 | 0.582701273649 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/R | 17656 |
Fn3-16 |
88 | rs1269389543 |
0.8004 | None | 1.0 | N | 0.813 | 0.435 | 0.582701273649 | gnomAD-4.0.0 | 6.20024E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47943E-06 | 0 | 0 |
| V/A | 17849 |
Fn3-17 |
86 | None | 0.1905 | None | 0.543 | N | 0.4 | 0.185 | 0.312001716656 | gnomAD-4.0.0 | 1.59586E-06 | None | None | None | None | N | None | 5.69217E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 17849 |
Fn3-17 |
86 | None | 0.1097 | None | 0.987 | N | 0.581 | 0.224 | 0.342400092842 | gnomAD-4.0.0 | 6.8514E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0009E-07 | 0 | 0 |
| V/L | 17849 |
Fn3-17 |
86 | rs746831431 |
0.3855 | -0.694 | 0.973 | N | 0.596 | 0.202 | None | gnomAD-2.1.1 | 8.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| V/L | 17849 |
Fn3-17 |
86 | rs746831431 |
0.3855 | -0.694 | 0.973 | N | 0.596 | 0.202 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 17849 |
Fn3-17 |
86 | rs746831431 |
0.3855 | -0.694 | 0.973 | N | 0.596 | 0.202 | None | gnomAD-4.0.0 | 4.84011E-05 | None | None | None | None | N | None | 1.33765E-05 | 0 | None | 0 | 0 | None | 0 | 1.64853E-04 | 6.44645E-05 | 0 | 0 |
| S/N | 18258 |
Fn3-20 |
93 | None | 0.9673 | None | 0.999 | D | 0.889 | 0.57 | 0.503498835695 | gnomAD-4.0.0 | 6.85289E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00726E-07 | 0 | 0 |
| S/T | 18258 |
Fn3-20 |
93 | rs770198717 |
0.6244 | -0.981 | 0.999 | N | 0.885 | 0.538 | 0.440915056915 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| V/M | 18565 |
Fn3-22 |
87 | rs2053387204 |
0.1886 | None | 0.484 | N | 0.583 | 0.132 | 0.245660935333 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 18565 |
Fn3-22 |
87 | rs2053387204 |
0.1886 | None | 0.484 | N | 0.583 | 0.132 | 0.245660935333 | gnomAD-4.0.0 | 3.13507E-06 | None | None | None | None | N | None | 0 | 1.71987E-05 | None | 0 | 0 | None | 0 | 0 | 3.42001E-06 | 0 | 0 |
| G/A | 19075 |
Fn3-26 |
88 | rs2154190109 |
0.1781 | None | 1.0 | N | 0.674 | 0.417 | 0.275641507738 | gnomAD-4.0.0 | 1.36882E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52576E-05 | None | 0 | 0 | 8.99635E-07 | 0 | 0 |
| G/E | 19075 |
Fn3-26 |
88 | None | 0.8543 | None | 1.0 | N | 0.81 | 0.448 | 0.424313518543 | gnomAD-4.0.0 | 1.36882E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52576E-05 | None | 0 | 0 | 0 | 1.15985E-05 | 0 |
| V/I | 19270 |
Fn3-27 |
88 | None | 0.0779 | None | None | N | 0.167 | 0.029 | 0.141422826196 | gnomAD-4.0.0 | 7.06833E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.20503E-07 | 0 | 0 |
| V/L | 19270 |
Fn3-27 |
88 | rs369440319 |
0.1635 | -0.473 | 0.004 | N | 0.487 | 0.11 | None | gnomAD-2.1.1 | 1.74287E-04 | None | None | None | None | N | None | 1.75312E-03 | 1.08015E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 19270 |
Fn3-27 |
88 | rs369440319 |
0.1635 | -0.473 | 0.004 | N | 0.487 | 0.11 | None | gnomAD-3.1.2 | 4.48117E-04 | None | None | None | None | N | None | 1.6222E-03 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 19270 |
Fn3-27 |
88 | rs369440319 |
0.1635 | -0.473 | 0.004 | N | 0.487 | 0.11 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| V/L | 19270 |
Fn3-27 |
88 | rs369440319 |
0.1635 | -0.473 | 0.004 | N | 0.487 | 0.11 | None | gnomAD-4.0.0 | 7.7236E-05 | None | None | None | None | N | None | 1.53E-03 | 7.53693E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 6.58393E-05 |
| S/G | 19666 |
Fn3-30 |
88 | rs776432732 |
0.4145 | -1.338 | 0.999 | D | 0.857 | 0.625 | 0.522611632499 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65893E-04 |
| S/R | 19666 |
Fn3-30 |
88 | rs776432732 |
0.9987 | -0.793 | 1.0 | D | 0.88 | 0.685 | 0.415820034956 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| S/T | 19666 |
Fn3-30 |
88 | None | 0.6958 | None | 0.999 | D | 0.873 | 0.513 | 0.548443230319 | gnomAD-4.0.0 | 1.59211E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43316E-05 | 0 |
| V/A | 19963 |
Fn3-32 |
87 | rs1553645836 |
0.1483 | None | 0.332 | N | 0.597 | 0.137 | 0.32053947749 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| V/I | 19963 |
Fn3-32 |
87 | rs768578399 |
0.086 | -0.331 | 0.004 | N | 0.207 | 0.064 | 0.340032825777 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| V/I | 19963 |
Fn3-32 |
87 | rs768578399 |
0.086 | -0.331 | 0.004 | N | 0.207 | 0.064 | 0.340032825777 | gnomAD-4.0.0 | 1.36913E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7994E-06 | 0 | 0 |
| D/E | 20062 |
Fn3-33 |
86 | rs1403249185 |
0.5557 | None | 1.0 | N | 0.592 | 0.225 | 0.223847106136 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.94024E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 20062 |
Fn3-33 |
86 | rs1403249185 |
0.5557 | None | 1.0 | N | 0.592 | 0.225 | 0.223847106136 | gnomAD-4.0.0 | 6.57462E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.94024E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 20062 |
Fn3-33 |
86 | rs2050223526 |
0.3074 | None | 1.0 | N | 0.715 | 0.324 | 0.32714864917 | gnomAD-4.0.0 | 1.59204E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43369E-05 | 0 |
| I/T | 20654 |
Fn3-37 |
86 | rs1244996285 |
0.1006 | -2.003 | 0.016 | N | 0.361 | 0.093 | 0.33085137897 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/T | 20654 |
Fn3-37 |
86 | rs1244996285 |
0.1006 | -2.003 | 0.016 | N | 0.361 | 0.093 | 0.33085137897 | gnomAD-4.0.0 | 1.59178E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| T/A | 20950 |
Fn3-39 |
87 | rs748774963 |
0.0682 | -1.138 | 0.349 | N | 0.735 | 0.072 | 0.218112801441 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.12397E-04 | None | 0 | None | 0 | 0 | 0 |
| T/A | 20950 |
Fn3-39 |
87 | rs748774963 |
0.0682 | -1.138 | 0.349 | N | 0.735 | 0.072 | 0.218112801441 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94024E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 20950 |
Fn3-39 |
87 | rs748774963 |
0.0682 | -1.138 | 0.349 | N | 0.735 | 0.072 | 0.218112801441 | gnomAD-4.0.0 | 1.28176E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.19223E-04 | None | 0 | 0 | 2.39412E-06 | 0 | 0 |
| S/I | 21050 |
Fn3-40 |
88 | None | 0.9894 | None | 1.0 | D | 0.918 | 0.705 | 0.75280674281 | gnomAD-4.0.0 | 1.4335E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.77047E-05 | 0 |
| S/T | 21050 |
Fn3-40 |
88 | None | 0.6557 | None | 0.999 | N | 0.913 | 0.561 | 0.495038369364 | gnomAD-4.0.0 | 1.1468E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.38653E-05 | 0 | 1.74046E-05 |
| A/T | 21157 |
Fn3-41 |
94 | rs1195739289 |
0.1059 | None | 1.0 | N | 0.777 | 0.279 | 0.126345400529 | gnomAD-4.0.0 | 1.60837E-06 | None | None | None | None | N | None | 5.69476E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 21352 |
Fn3-42 |
87 | rs746114626 |
0.1084 | 0.117 | 0.055 | N | 0.505 | 0.106 | 0.268660756437 | gnomAD-2.1.1 | 4.42E-05 | None | None | None | None | N | None | 0 | 2.89788E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65563E-04 |
| T/I | 21352 |
Fn3-42 |
87 | rs746114626 |
0.1084 | 0.117 | 0.055 | N | 0.505 | 0.106 | 0.268660756437 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 21352 |
Fn3-42 |
87 | rs746114626 |
0.1084 | 0.117 | 0.055 | N | 0.505 | 0.106 | 0.268660756437 | gnomAD-4.0.0 | 7.43883E-06 | None | None | None | None | N | None | 0 | 1.8345E-04 | None | 0 | 0 | None | 0 | 0 | 8.47859E-07 | 0 | 0 |
| R/G | 21453 |
Fn3-43 |
88 | rs1014690727 |
0.6978 | -1.841 | 0.722 | N | 0.591 | 0.198 | 0.341934017632 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/G | 21453 |
Fn3-43 |
88 | rs1014690727 |
0.6978 | -1.841 | 0.722 | N | 0.591 | 0.198 | 0.341934017632 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/G | 21453 |
Fn3-43 |
88 | rs1014690727 |
0.6978 | -1.841 | 0.722 | N | 0.591 | 0.198 | 0.341934017632 | gnomAD-4.0.0 | 8.97411E-06 | None | None | None | None | I | None | 6.76613E-05 | 0 | None | 0 | 4.85838E-05 | None | 0 | 0 | 2.39524E-06 | 0 | 0 |
| R/K | 21453 |
Fn3-43 |
88 | None | 0.248 | None | 0.008 | N | 0.227 | 0.088 | None | gnomAD-4.0.0 | 1.36894E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99776E-07 | 0 | 1.65744E-05 |
| R/T | 21453 |
Fn3-43 |
88 | rs765575975 |
0.5981 | None | 0.722 | N | 0.555 | 0.144 | 0.280181792013 | gnomAD-4.0.0 | 1.36894E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79955E-06 | 0 | 0 |
| L/F | 21646 |
Fn3-44 |
88 | rs1203566511 |
0.4245 | None | 0.933 | N | 0.609 | 0.321 | 0.591436515814 | gnomAD-4.0.0 | 1.59196E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85976E-06 | 0 | 0 |
| S/R | 21746 |
Fn3-45 |
88 | None | 0.9979 | None | 0.999 | D | 0.84 | 0.61 | 0.550545596621 | gnomAD-4.0.0 | 8.16716E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.17925E-05 | 1.4741E-05 | 0 |
| S/P | 21846 |
Fn3-46 |
90 | None | 0.9893 | None | 1.0 | D | 0.859 | 0.704 | 0.667980572847 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/L | 22042 |
Fn3-47 |
87 | rs764678997 |
0.1261 | -0.134 | 0.001 | N | 0.395 | 0.06 | 0.237489013734 | gnomAD-2.1.1 | 4.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.47E-05 | None | 0 | 0 | 0 |
| V/L | 22042 |
Fn3-47 |
87 | rs764678997 |
0.1261 | -0.134 | 0.001 | N | 0.395 | 0.06 | 0.237489013734 | gnomAD-4.0.0 | 1.61948E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.47545E-05 | 0 |
| S/N | 22142 |
Fn3-48 |
88 | rs771038770 |
0.9741 | -1.124 | 0.999 | D | 0.889 | 0.594 | 0.532696708436 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| G/A | 22440 |
Fn3-50 |
87 | rs2047328766 |
0.086 | None | 0.309 | N | 0.56 | 0.154 | 0.19670166235 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/A | 22440 |
Fn3-50 |
87 | rs2047328766 |
0.086 | None | 0.309 | N | 0.56 | 0.154 | 0.19670166235 | gnomAD-4.0.0 | 6.57644E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47089E-05 | 0 | 0 |
| G/C | 22440 |
Fn3-50 |
87 | rs727503576 |
0.1393 | -0.348 | 0.007 | N | 0.544 | 0.226 | 0.220303561663 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/C | 22440 |
Fn3-50 |
87 | rs727503576 |
0.1393 | -0.348 | 0.007 | N | 0.544 | 0.226 | 0.220303561663 | gnomAD-4.0.0 | 3.42245E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.79979E-05 | 0 |
| G/S | 22440 |
Fn3-50 |
87 | rs727503576 |
0.1331 | None | 0.924 | N | 0.619 | 0.089 | 0.144782658237 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/S | 22440 |
Fn3-50 |
87 | rs727503576 |
0.1331 | None | 0.924 | N | 0.619 | 0.089 | 0.144782658237 | gnomAD-4.0.0 | 9.29982E-06 | None | None | None | None | I | None | 2.67201E-05 | 3.33622E-05 | None | 0 | 0 | None | 0 | 0 | 9.32624E-06 | 0 | 0 |
| S/N | 22535 |
Fn3-51 |
85 | rs375676529 |
0.1273 | -0.862 | 0.351 | D | 0.689 | 0.288 | None | gnomAD-2.1.1 | 7.88E-05 | None | None | None | None | N | None | 1.24059E-04 | 5.66E-05 | None | 0 | 0 | None | 0 | None | 8E-05 | 1.17978E-04 | 0 |
| S/N | 22535 |
Fn3-51 |
85 | rs375676529 |
0.1273 | -0.862 | 0.351 | D | 0.689 | 0.288 | None | gnomAD-3.1.2 | 1.24969E-04 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 1.88573E-04 | 0 | 1.91221E-04 | 0 | 0 |
| S/N | 22535 |
Fn3-51 |
85 | rs375676529 |
0.1273 | -0.862 | 0.351 | D | 0.689 | 0.288 | None | gnomAD-4.0.0 | 1.20259E-04 | None | None | None | None | N | None | 9.34979E-05 | 0 | None | 0 | 0 | None | 3.12705E-05 | 0 | 1.49215E-04 | 0 | 1.44143E-04 |
| S/R | 22535 |
Fn3-51 |
85 | rs750847940 |
0.3539 | -0.536 | 0.002 | N | 0.512 | 0.414 | 0.152612264143 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| S/R | 22535 |
Fn3-51 |
85 | rs750847940 |
0.3539 | -0.536 | 0.002 | N | 0.512 | 0.414 | 0.152612264143 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 22535 |
Fn3-51 |
85 | rs750847940 |
0.3539 | -0.536 | 0.002 | N | 0.512 | 0.414 | 0.152612264143 | gnomAD-4.0.0 | 6.84406E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99669E-07 | 0 | 0 |
| L/M | 22730 |
Fn3-52 |
88 | rs1273726879 |
0.1976 | -0.652 | 0.994 | N | 0.777 | 0.211 | 0.52250569628 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.3E-05 | None | 0 | 0 | 0 |
| L/M | 22730 |
Fn3-52 |
88 | rs1273726879 |
0.1976 | -0.652 | 0.994 | N | 0.777 | 0.211 | 0.52250569628 | gnomAD-4.0.0 | 1.59554E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43951E-05 | 0 |
| S/G | 22830 |
Fn3-53 |
88 | rs2046834527 |
0.4917 | None | 0.999 | D | 0.857 | 0.729 | 0.50466331119 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| S/G | 22830 |
Fn3-53 |
88 | rs2046834527 |
0.4917 | None | 0.999 | D | 0.857 | 0.729 | 0.50466331119 | gnomAD-4.0.0 | 7.43893E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32613E-06 | 0 | 1.60159E-05 |
| S/L | 22929 |
Fn3-54 |
89 | rs764365298 |
0.8756 | -0.083 | 0.587 | D | 0.823 | 0.62 | 0.695824657773 | gnomAD-2.1.1 | 8.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| S/L | 22929 |
Fn3-54 |
89 | rs764365298 |
0.8756 | -0.083 | 0.587 | D | 0.823 | 0.62 | 0.695824657773 | gnomAD-4.0.0 | 3.18796E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72285E-06 | 0 | 0 |
| S/P | 22929 |
Fn3-54 |
89 | rs1277213346 |
0.9781 | -0.383 | 0.994 | D | 0.851 | 0.728 | 0.533950601487 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/P | 22929 |
Fn3-54 |
89 | rs1277213346 |
0.9781 | -0.383 | 0.994 | D | 0.851 | 0.728 | 0.533950601487 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 22929 |
Fn3-54 |
89 | rs1277213346 |
0.9781 | -0.383 | 0.994 | D | 0.851 | 0.728 | 0.533950601487 | gnomAD-4.0.0 | 6.57609E-06 | None | None | None | None | N | None | 2.41406E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 23126 |
Fn3-55 |
87 | rs756671149 |
0.0802 | -0.557 | 0.309 | N | 0.477 | 0.055 | 0.188950314367 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| V/I | 23126 |
Fn3-55 |
87 | rs756671149 |
0.0802 | -0.557 | 0.309 | N | 0.477 | 0.055 | 0.188950314367 | gnomAD-4.0.0 | 6.84363E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51991E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 23126 |
Fn3-55 |
87 | rs756671149 |
0.1486 | -0.56 | 0.003 | N | 0.232 | 0.089 | 0.0954503805726 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| V/L | 23126 |
Fn3-55 |
87 | rs756671149 |
0.1486 | -0.56 | 0.003 | N | 0.232 | 0.089 | 0.0954503805726 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 0 | 3.27439E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.79386E-04 |
| V/L | 23126 |
Fn3-55 |
87 | rs756671149 |
0.1486 | -0.56 | 0.003 | N | 0.232 | 0.089 | 0.0954503805726 | gnomAD-4.0.0 | 9.91761E-06 | None | None | None | None | N | None | 0 | 1.50035E-04 | None | 0 | 0 | None | 0 | 0 | 4.23899E-06 | 0 | 3.20359E-05 |
| S/G | 23226 |
Fn3-56 |
88 | rs72646885 |
0.4219 | -1.267 | 0.999 | N | 0.887 | 0.566 | None | gnomAD-2.1.1 | 7.21678E-03 | None | None | None | None | N | None | 9.50963E-04 | 4.36038E-03 | None | 3.00155E-02 | 0 | None | 1.13138E-02 | None | 1.99808E-03 | 8.30656E-03 | 1.05426E-02 |
| S/G | 23226 |
Fn3-56 |
88 | rs72646885 |
0.4219 | -1.267 | 0.999 | N | 0.887 | 0.566 | None | gnomAD-3.1.2 | 5.76458E-03 | None | None | None | None | N | None | 1.32639E-03 | 4.45143E-03 | 0 | 3.31221E-02 | 0 | None | 2.07117E-03 | 2.8481E-02 | 8.02988E-03 | 8.70647E-03 | 9.56938E-03 |
| S/G | 23226 |
Fn3-56 |
88 | rs72646885 |
0.4219 | -1.267 | 0.999 | N | 0.887 | 0.566 | None | 1000 genomes | 2.99521E-03 | None | None | None | None | N | None | 0 | 8.6E-03 | None | None | 0 | 6E-03 | None | None | None | 3.1E-03 | None |
| S/G | 23226 |
Fn3-56 |
88 | rs72646885 |
0.4219 | -1.267 | 0.999 | N | 0.887 | 0.566 | None | gnomAD-4.0.0 | 7.02526E-03 | None | None | None | None | N | None | 1.41258E-03 | 4.7327E-03 | None | 3.16238E-02 | 0 | None | 2.73378E-03 | 1.76568E-02 | 6.87666E-03 | 1.14003E-02 | 9.25274E-03 |
| S/N | 23226 |
Fn3-56 |
88 | None | 0.9677 | None | 0.999 | D | 0.897 | 0.509 | 0.440182696023 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/V | 23328 |
Fn3-57 |
89 | rs1466750954 |
0.2102 | -0.262 | 0.999 | N | 0.67 | 0.382 | 0.583302769791 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | I | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 3.56E-05 | 0 |
| A/V | 23328 |
Fn3-57 |
89 | rs1466750954 |
0.2102 | -0.262 | 0.999 | N | 0.67 | 0.382 | 0.583302769791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 23328 |
Fn3-57 |
89 | rs1466750954 |
0.2102 | -0.262 | 0.999 | N | 0.67 | 0.382 | 0.583302769791 | gnomAD-4.0.0 | 5.70335E-05 | None | None | None | None | I | None | 2.6713E-05 | 1.66789E-05 | None | 0 | 0 | None | 0 | 0 | 7.4608E-05 | 0 | 1.60174E-05 |
| T/I | 23521 |
Fn3-58 |
87 | rs775589244 |
0.1066 | -0.005 | 0.012 | N | 0.467 | 0.125 | 0.17258766438 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 23521 |
Fn3-58 |
87 | rs775589244 |
0.1066 | -0.005 | 0.012 | N | 0.467 | 0.125 | 0.17258766438 | gnomAD-4.0.0 | 6.84256E-07 | None | None | None | None | I | None | 0 | 2.23604E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 23521 |
Fn3-58 |
87 | rs1007385866 |
0.7055 | None | 0.055 | N | 0.501 | 0.108 | 0.0297737177859 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/P | 23521 |
Fn3-58 |
87 | rs1007385866 |
0.7055 | None | 0.055 | N | 0.501 | 0.108 | 0.0297737177859 | gnomAD-4.0.0 | 6.5735E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47067E-05 | 0 | 0 |
| T/R | 23521 |
Fn3-58 |
87 | rs775589244 |
0.1673 | -0.644 | None | N | 0.4 | 0.118 | None | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | I | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 5.34E-05 | 0 |
| T/R | 23521 |
Fn3-58 |
87 | rs775589244 |
0.1673 | -0.644 | None | N | 0.4 | 0.118 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/R | 23521 |
Fn3-58 |
87 | rs775589244 |
0.1673 | -0.644 | None | N | 0.4 | 0.118 | None | gnomAD-4.0.0 | 1.73537E-05 | None | None | None | None | I | None | 0 | 3.33456E-05 | None | 0 | 0 | None | 0 | 1.64582E-04 | 1.78017E-05 | 0 | 6.40492E-05 |
| R/K | 23617 |
Fn3-59 |
86 | None | 0.1791 | None | 0.639 | N | 0.554 | 0.149 | 0.207176502487 | gnomAD-4.0.0 | 1.59219E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85933E-06 | 0 | 0 |
| R/T | 23617 |
Fn3-59 |
86 | None | 0.4927 | None | 0.973 | N | 0.653 | 0.331 | 0.459995458672 | gnomAD-4.0.0 | 1.59219E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85933E-06 | 0 | 0 |
| I/T | 23813 |
Fn3-60 |
88 | rs1304761942 |
0.385 | -0.838 | 0.546 | N | 0.483 | 0.32 | 0.642158408529 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 23813 |
Fn3-60 |
88 | rs1304761942 |
0.385 | -0.838 | 0.546 | N | 0.483 | 0.32 | 0.642158408529 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| I/T | 23813 |
Fn3-60 |
88 | rs1304761942 |
0.385 | -0.838 | 0.546 | N | 0.483 | 0.32 | 0.642158408529 | gnomAD-4.0.0 | 3.84578E-06 | None | None | None | None | N | None | 0 | 1.69578E-05 | None | 0 | 0 | None | 0 | 0 | 2.39437E-06 | 1.34124E-05 | 0 |
| S/N | 23913 |
Fn3-61 |
88 | rs1709335824 |
0.9641 | None | 0.999 | D | 0.892 | 0.576 | 0.49676076625 | gnomAD-4.0.0 | 1.59182E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8593E-06 | 0 | 0 |
| A/D | 24411 |
Fn3-65 |
89 | rs55991022 |
0.8341 | -1.913 | 0.994 | N | 0.777 | 0.546 | 0.660788651602 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| A/D | 24411 |
Fn3-65 |
89 | rs55991022 |
0.8341 | -1.913 | 0.994 | N | 0.777 | 0.546 | 0.660788651602 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/D | 24411 |
Fn3-65 |
89 | rs55991022 |
0.8341 | -1.913 | 0.994 | N | 0.777 | 0.546 | 0.660788651602 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| A/D | 24411 |
Fn3-65 |
89 | rs55991022 |
0.8341 | -1.913 | 0.994 | N | 0.777 | 0.546 | 0.660788651602 | gnomAD-4.0.0 | 1.48757E-05 | None | None | None | None | I | None | 1.33312E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.86506E-05 | 0 | 1.60123E-05 |
| A/T | 24411 |
Fn3-65 |
89 | rs772653954 |
0.1443 | -0.775 | 0.988 | N | 0.724 | 0.223 | 0.300784259202 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| A/T | 24411 |
Fn3-65 |
89 | rs772653954 |
0.1443 | -0.775 | 0.988 | N | 0.724 | 0.223 | 0.300784259202 | gnomAD-4.0.0 | 2.05313E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99591E-07 | 2.31884E-05 | 0 |
| L/P | 25291 |
Fn3-71 |
88 | rs1559388448 |
0.9876 | None | 0.994 | D | 0.851 | 0.547 | 0.82834384376 | gnomAD-4.0.0 | 2.05307E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69871E-06 | 0 | 0 |
| S/I | 25391 |
Fn3-72 |
88 | None | 0.9726 | None | 1.0 | D | 0.891 | 0.597 | 0.719532834518 | gnomAD-4.0.0 | 1.59509E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86554E-06 | 0 | 0 |
| S/R | 25391 |
Fn3-72 |
88 | None | 0.9983 | None | 1.0 | D | 0.876 | 0.692 | 0.435808882951 | gnomAD-4.0.0 | 6.84885E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0016E-07 | 0 | 0 |
| A/D | 25493 |
Fn3-73 |
89 | rs1707414418 |
0.7644 | None | 1.0 | N | 0.797 | 0.425 | 0.412328234245 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| A/D | 25493 |
Fn3-73 |
89 | rs1707414418 |
0.7644 | None | 1.0 | N | 0.797 | 0.425 | 0.412328234245 | gnomAD-4.0.0 | 6.57739E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 25493 |
Fn3-73 |
89 | rs1707415905 |
0.1044 | None | 1.0 | N | 0.742 | 0.266 | 0.272639205421 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 25687 |
Fn3-74 |
87 | rs1707146929 |
0.095 | None | 0.967 | N | 0.54 | 0.306 | 0.202949470691 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| A/T | 25687 |
Fn3-74 |
87 | rs1707146929 |
0.095 | None | 0.967 | N | 0.54 | 0.306 | 0.202949470691 | gnomAD-4.0.0 | 6.5767E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| R/Q | 25783 |
Fn3-75 |
86 | rs777428147 |
0.2103 | -0.448 | 1.0 | N | 0.585 | 0.263 | 0.203808441222 | gnomAD-2.1.1 | 6.1E-05 | None | None | None | None | I | None | 4.14E-05 | 1.13449E-04 | None | 0 | 1.03157E-04 | None | 1.3113E-04 | None | 0 | 3.94E-05 | 1.41483E-04 |
| R/Q | 25783 |
Fn3-75 |
86 | rs777428147 |
0.2103 | -0.448 | 1.0 | N | 0.585 | 0.263 | 0.203808441222 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 1.93573E-04 | None | 0 | 0 | 2.94E-05 | 0 | 9.56938E-04 |
| R/Q | 25783 |
Fn3-75 |
86 | rs777428147 |
0.2103 | -0.448 | 1.0 | N | 0.585 | 0.263 | 0.203808441222 | gnomAD-4.0.0 | 4.09253E-05 | None | None | None | None | I | None | 4.0078E-05 | 6.67534E-05 | None | 0 | 6.70391E-05 | None | 0 | 0 | 3.98538E-05 | 5.49571E-05 | 6.40861E-05 |
| R/W | 25783 |
Fn3-75 |
86 | rs758010128 |
0.6034 | -0.295 | 1.0 | N | 0.674 | 0.4 | 0.276482976112 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 0 | 8.72E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/W | 25783 |
Fn3-75 |
86 | rs758010128 |
0.6034 | -0.295 | 1.0 | N | 0.674 | 0.4 | 0.276482976112 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/W | 25783 |
Fn3-75 |
86 | rs758010128 |
0.6034 | -0.295 | 1.0 | N | 0.674 | 0.4 | 0.276482976112 | gnomAD-4.0.0 | 6.20017E-06 | None | None | None | None | I | None | 0 | 5.00634E-05 | None | 0 | 0 | None | 0 | 0 | 4.23935E-06 | 1.09895E-05 | 1.60215E-05 |
| S/R | 26077 |
Fn3-77 |
88 | rs1553596375 |
0.9986 | None | 0.991 | D | 0.852 | 0.752 | 0.4722639086 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 26077 |
Fn3-77 |
88 | rs1553596375 |
0.9986 | None | 0.991 | D | 0.852 | 0.752 | 0.4722639086 | gnomAD-4.0.0 | 2.56329E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78822E-06 | 0 | 0 |
| S/P | 26176 |
Fn3-78 |
89 | None | 0.9928 | None | 0.994 | D | 0.819 | 0.73 | 0.584954716481 | gnomAD-4.0.0 | 6.85091E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00426E-07 | 0 | 0 |
| L/M | 26373 |
Fn3-79 |
88 | None | 0.2116 | None | 0.998 | D | 0.741 | 0.268 | 0.483596354421 | gnomAD-4.0.0 | 4.77468E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71808E-06 | 0 | 3.0259E-05 |
| S/G | 26473 |
Fn3-80 |
88 | None | 0.2523 | None | 0.999 | D | 0.882 | 0.686 | 0.469907520169 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 26473 |
Fn3-80 |
88 | None | 0.851 | None | 0.999 | D | 0.889 | 0.538 | 0.503744809241 | gnomAD-4.0.0 | 6.84346E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99543E-07 | 0 | 0 |
| T/P | 26575 |
Fn3-81 |
89 | rs1705878064 |
0.3151 | None | 0.317 | N | 0.608 | 0.064 | 0.110078149338 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 26575 |
Fn3-81 |
89 | rs1705878064 |
0.3151 | None | 0.317 | N | 0.608 | 0.064 | 0.110078149338 | gnomAD-4.0.0 | 2.03E-06 | None | None | None | None | I | None | 3.49357E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 26769 |
Fn3-82 |
87 | None | 0.0772 | None | None | N | 0.215 | 0.103 | 0.213573922156 | gnomAD-4.0.0 | 1.36854E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79912E-06 | 0 | 0 |
| V/L | 26769 |
Fn3-82 |
87 | None | 0.1956 | None | 0.012 | N | 0.493 | 0.07 | 0.225215365344 | gnomAD-4.0.0 | 6.84273E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| V/M | 26769 |
Fn3-82 |
87 | rs745315690 |
0.1225 | None | 0.303 | N | 0.54 | 0.067 | 0.28492961333 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 26769 |
Fn3-82 |
87 | rs745315690 |
0.1225 | None | 0.303 | N | 0.54 | 0.067 | 0.28492961333 | gnomAD-4.0.0 | 1.2395E-06 | None | None | None | None | I | None | 0 | 1.6675E-05 | None | 0 | 2.22846E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 26865 |
Fn3-83 |
86 | rs1471370920 |
0.1753 | -0.694 | 0.994 | N | 0.585 | 0.285 | 0.42805410278 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/K | 26865 |
Fn3-83 |
86 | rs1471370920 |
0.1753 | -0.694 | 0.994 | N | 0.585 | 0.285 | 0.42805410278 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 26865 |
Fn3-83 |
86 | rs1471370920 |
0.1753 | -0.694 | 0.994 | N | 0.585 | 0.285 | 0.42805410278 | gnomAD-4.0.0 | 6.5754E-06 | None | None | None | None | I | None | 2.41383E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/S | 26865 |
Fn3-83 |
86 | rs878865997 |
0.7017 | None | 1.0 | N | 0.786 | 0.39 | 0.24896430686 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/S | 26865 |
Fn3-83 |
86 | rs878865997 |
0.7017 | None | 1.0 | N | 0.786 | 0.39 | 0.24896430686 | gnomAD-4.0.0 | 1.23958E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69545E-06 | 0 | 0 |
| S/R | 27159 |
Fn3-85 |
88 | None | 0.9981 | None | 0.983 | D | 0.853 | 0.722 | 0.59634542923 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/T | 27159 |
Fn3-85 |
88 | rs1173082517 |
0.6284 | -0.713 | 0.892 | D | 0.826 | 0.545 | 0.367042808489 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | I | None | 1.14705E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/C | 27258 |
Fn3-86 |
89 | rs755629282 |
0.6358 | -0.869 | 1.0 | D | 0.887 | 0.508 | 0.771676275692 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| S/C | 27258 |
Fn3-86 |
89 | rs755629282 |
0.6358 | -0.869 | 1.0 | D | 0.887 | 0.508 | 0.771676275692 | gnomAD-4.0.0 | 6.84246E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99478E-07 | 0 | 0 |
| S/Y | 27258 |
Fn3-86 |
89 | None | 0.9949 | None | 1.0 | D | 0.925 | 0.512 | 0.861820853342 | gnomAD-4.0.0 | 6.84246E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99478E-07 | 0 | 0 |
| L/F | 27456 |
Fn3-87 |
88 | rs1233877374 |
0.5207 | None | 0.994 | N | 0.679 | 0.255 | 0.489311470972 | gnomAD-4.0.0 | 1.36846E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79897E-06 | 0 | 0 |
| L/M | 27456 |
Fn3-87 |
88 | None | 0.181 | None | 0.983 | N | 0.701 | 0.268 | 0.365509141856 | gnomAD-4.0.0 | 1.36846E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79897E-06 | 0 | 0 |
| S/G | 27556 |
Fn3-88 |
88 | rs1181121628 |
0.35 | -1.004 | 0.999 | D | 0.887 | 0.626 | 0.49908893446 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| S/G | 27556 |
Fn3-88 |
88 | rs1181121628 |
0.35 | -1.004 | 0.999 | D | 0.887 | 0.626 | 0.49908893446 | gnomAD-4.0.0 | 1.36851E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79899E-06 | 0 | 0 |
| A/T | 27658 |
Fn3-89 |
89 | rs150150605 |
0.1372 | -1.189 | 0.698 | N | 0.591 | 0.192 | None | gnomAD-2.1.1 | 2.86E-05 | None | None | None | None | N | None | 2.06629E-04 | 8.48E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 27658 |
Fn3-89 |
89 | rs150150605 |
0.1372 | -1.189 | 0.698 | N | 0.591 | 0.192 | None | gnomAD-3.1.2 | 9.86E-05 | None | None | None | None | N | None | 3.62126E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 27658 |
Fn3-89 |
89 | rs150150605 |
0.1372 | -1.189 | 0.698 | N | 0.591 | 0.192 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| A/T | 27658 |
Fn3-89 |
89 | rs150150605 |
0.1372 | -1.189 | 0.698 | N | 0.591 | 0.192 | None | gnomAD-4.0.0 | 1.92102E-05 | None | None | None | None | N | None | 3.5999E-04 | 6.66778E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/D | 27852 |
Fn3-90 |
87 | None | 0.7798 | None | 0.996 | N | 0.758 | 0.435 | 0.616786663822 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/D | 27852 |
Fn3-90 |
87 | None | 0.7798 | None | 0.996 | N | 0.758 | 0.435 | 0.616786663822 | gnomAD-4.0.0 | 6.57315E-06 | None | None | None | None | I | None | 2.41278E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/G | 27852 |
Fn3-90 |
87 | rs541476378 |
0.1889 | None | 0.873 | N | 0.581 | 0.255 | 0.280987212366 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| R/T | 27948 |
Fn3-91 |
86 | None | 0.5423 | None | 0.904 | N | 0.491 | 0.155 | 0.394079506076 | gnomAD-4.0.0 | 1.59229E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85927E-06 | 0 | 0 |
| S/G | 28141 |
Fn3-92 |
87 | None | 0.1284 | None | 0.061 | N | 0.571 | 0.314 | 0.191931220699 | gnomAD-4.0.0 | 2.74299E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.6046E-06 | 0 | 0 |
| S/I | 28141 |
Fn3-92 |
87 | rs748707866 |
0.1202 | None | None | N | 0.535 | 0.181 | 0.504727117792 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/I | 28141 |
Fn3-92 |
87 | rs748707866 |
0.1202 | None | None | N | 0.535 | 0.181 | 0.504727117792 | gnomAD-4.0.0 | 6.57022E-06 | None | None | None | None | N | None | 2.4122E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 28141 |
Fn3-92 |
87 | None | 0.5498 | None | 0.001 | D | 0.554 | 0.353 | 0.299086750705 | gnomAD-4.0.0 | 1.60286E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44001E-05 | 0 |
| S/T | 28141 |
Fn3-92 |
87 | rs748707866 |
0.0706 | -0.866 | 0.001 | N | 0.331 | 0.238 | 0.148003135375 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.24442E-04 | None | 0 | None | 0 | 0 | 0 |
| S/T | 28141 |
Fn3-92 |
87 | rs748707866 |
0.0706 | -0.866 | 0.001 | N | 0.331 | 0.238 | 0.148003135375 | gnomAD-4.0.0 | 6.40158E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11383E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 28537 |
Fn3-95 |
88 | None | 0.9704 | None | 1.0 | N | 0.787 | 0.534 | 0.774090168342 | gnomAD-4.0.0 | 1.59253E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78102E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 28737 |
Fn3-97 |
87 | None | 0.8212 | None | 0.994 | D | 0.861 | 0.499 | 0.558070701127 | gnomAD-4.0.0 | 1.59146E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02389E-05 |
| A/G | 28931 |
Fn3-98 |
87 | rs774479678 |
0.1328 | -1.52 | 0.113 | N | 0.522 | 0.156 | 0.110078149338 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/G | 28931 |
Fn3-98 |
87 | rs774479678 |
0.1328 | -1.52 | 0.113 | N | 0.522 | 0.156 | 0.110078149338 | gnomAD-4.0.0 | 1.2499E-06 | None | None | None | None | N | None | 2.69644E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 28931 |
Fn3-98 |
87 | None | 0.0758 | None | 0.005 | N | 0.339 | 0.055 | 0.0884992946249 | gnomAD-4.0.0 | 1.20035E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31253E-06 | 0 | 0 |
| A/V | 28931 |
Fn3-98 |
87 | None | 0.0974 | None | 0.047 | N | 0.208 | 0.072 | 0.178374595973 | gnomAD-4.0.0 | 6.90584E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.05107E-07 | 0 | 0 |
| R/K | 29027 |
Fn3-99 |
86 | rs763879330 |
0.1296 | -1.026 | None | N | 0.247 | 0.151 | 0.305086939656 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| R/K | 29027 |
Fn3-99 |
86 | rs763879330 |
0.1296 | -1.026 | None | N | 0.247 | 0.151 | 0.305086939656 | gnomAD-4.0.0 | 3.42146E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69846E-06 | 1.15961E-05 | 1.65689E-05 |
| I/T | 29224 |
Fn3-100 |
88 | rs878915392 |
0.068 | -2.323 | 0.001 | N | 0.488 | 0.254 | 0.514587094315 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/T | 29224 |
Fn3-100 |
88 | rs878915392 |
0.068 | -2.323 | 0.001 | N | 0.488 | 0.254 | 0.514587094315 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 29224 |
Fn3-100 |
88 | rs878915392 |
0.068 | -2.323 | 0.001 | N | 0.488 | 0.254 | 0.514587094315 | gnomAD-4.0.0 | 4.33743E-06 | None | None | None | None | N | None | 5.3376E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69511E-06 | 1.09791E-05 | 0 |
| S/P | 29423 |
Fn3-102 |
89 | rs1701723735 |
0.9713 | None | 1.0 | D | 0.88 | 0.726 | 0.591671430083 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 29423 |
Fn3-102 |
89 | rs1701723735 |
0.9713 | None | 1.0 | D | 0.88 | 0.726 | 0.591671430083 | gnomAD-4.0.0 | 6.56953E-06 | None | None | None | None | I | None | 2.41208E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 29423 |
Fn3-102 |
89 | None | 0.3267 | None | 0.999 | D | 0.884 | 0.593 | 0.473931330248 | gnomAD-4.0.0 | 1.59136E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| S/A | 29720 |
Fn3-104 |
88 | rs555559270 |
0.437 | -0.701 | 0.973 | D | 0.757 | 0.574 | 0.407632638399 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| S/A | 29720 |
Fn3-104 |
88 | rs555559270 |
0.437 | -0.701 | 0.973 | D | 0.757 | 0.574 | 0.407632638399 | gnomAD-4.0.0 | 2.74763E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60203E-06 | 0 | 0 |
| S/Y | 29720 |
Fn3-104 |
88 | rs1553543837 |
0.983 | None | 0.999 | D | 0.903 | 0.632 | 0.832371627952 | gnomAD-4.0.0 | 1.60622E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.99314E-05 | 0 | 0 | 0 | 0 |
| I/M | 29822 |
Fn3-105 |
89 | rs754018369 |
0.0869 | -0.885 | 0.075 | N | 0.421 | 0.071 | 0.245660935333 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| I/M | 29822 |
Fn3-105 |
89 | rs754018369 |
0.0869 | -0.885 | 0.075 | N | 0.421 | 0.071 | 0.245660935333 | gnomAD-4.0.0 | 1.59175E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43357E-05 | 0 |
| I/T | 29822 |
Fn3-105 |
89 | None | 0.0883 | None | 0.722 | N | 0.599 | 0.218 | 0.504297271243 | gnomAD-4.0.0 | 2.73721E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7991E-06 | 2.31949E-05 | 0 |
| I/V | 29822 |
Fn3-105 |
89 | None | 0.066 | None | 0.19 | N | 0.416 | 0.096 | 0.332133492242 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/R | 30019 |
Fn3-106 |
87 | rs774538632 |
0.4725 | -1.066 | 0.966 | N | 0.869 | 0.336 | 0.714032942311 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| C/R | 30019 |
Fn3-106 |
87 | rs774538632 |
0.4725 | -1.066 | 0.966 | N | 0.869 | 0.336 | 0.714032942311 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43283E-05 | 0 |
| V/L | 30115 |
Fn3-107 |
86 | rs773932096 |
0.2596 | -0.37 | 0.435 | N | 0.441 | 0.173 | 0.20549828249 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 30115 |
Fn3-107 |
86 | rs773932096 |
0.2596 | -0.37 | 0.435 | N | 0.441 | 0.173 | 0.20549828249 | gnomAD-4.0.0 | 1.59131E-06 | None | None | None | None | I | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 30411 |
Fn3-109 |
88 | None | 0.954 | None | 0.999 | D | 0.893 | 0.584 | 0.615520507219 | gnomAD-4.0.0 | 3.22706E-06 | None | None | None | None | N | None | 5.76768E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.45539E-05 | 0 |
| S/T | 30411 |
Fn3-109 |
88 | rs1482766164 |
0.4414 | None | 0.999 | D | 0.887 | 0.557 | 0.551961605406 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88018E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 30411 |
Fn3-109 |
88 | rs1482766164 |
0.4414 | None | 0.999 | D | 0.887 | 0.557 | 0.551961605406 | gnomAD-4.0.0 | 6.57436E-06 | None | None | None | None | N | None | 0 | 0 | None | 2.88018E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/R | 30706 |
Fn3-111 |
88 | rs779567470 |
0.3607 | -1.065 | 0.999 | N | 0.855 | 0.622 | 0.79003172286 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
| S/N | 30807 |
Fn3-112 |
89 | rs1698363944 |
0.935 | None | 0.999 | D | 0.884 | 0.545 | 0.443388199986 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06697E-04 | 0 |
| S/N | 30807 |
Fn3-112 |
89 | rs1698363944 |
0.935 | None | 0.999 | D | 0.884 | 0.545 | 0.443388199986 | gnomAD-4.0.0 | 6.57056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.06697E-04 | 0 |
| S/R | 30807 |
Fn3-112 |
89 | rs748024667 |
0.9923 | -0.998 | 1.0 | D | 0.853 | 0.676 | 0.470401675101 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| S/T | 30807 |
Fn3-112 |
89 | None | 0.4099 | None | 0.999 | D | 0.875 | 0.552 | 0.381580015636 | gnomAD-4.0.0 | 6.00162E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| C/Y | 30908 |
Fn3-113 |
88 | None | 0.2007 | None | 0.303 | N | 0.634 | 0.248 | 0.437527004654 | gnomAD-4.0.0 | 1.5912E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85789E-06 | 0 | 0 |
| Y/C | 31102 |
Fn3-114 |
87 | rs374084427 |
0.0619 | -1.096 | 0.004 | N | 0.535 | 0.197 | None | gnomAD-2.1.1 | 4.29E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.0248E-04 | None | 0 | None | 4E-05 | 7.05E-05 | 0 |
| Y/C | 31102 |
Fn3-114 |
87 | rs374084427 |
0.0619 | -1.096 | 0.004 | N | 0.535 | 0.197 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.92678E-04 | None | 9.41E-05 | 0 | 4.42E-05 | 0 | 0 |
| Y/C | 31102 |
Fn3-114 |
87 | rs374084427 |
0.0619 | -1.096 | 0.004 | N | 0.535 | 0.197 | None | gnomAD-4.0.0 | 3.65641E-05 | None | None | None | None | I | None | 4.00716E-05 | 0 | None | 0 | 4.45553E-05 | None | 1.5624E-05 | 0 | 4.23821E-05 | 0 | 4.80354E-05 |
| Y/F | 31102 |
Fn3-114 |
87 | None | 0.0726 | None | 0.712 | N | 0.495 | 0.097 | 0.210429274316 | gnomAD-4.0.0 | 6.84183E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| Y/H | 31102 |
Fn3-114 |
87 | None | 0.1226 | None | 0.009 | N | 0.43 | 0.087 | 0.199424873507 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/G | 31198 |
Fn3-115 |
86 | rs751148256 |
0.6672 | -1.943 | 0.99 | N | 0.606 | 0.239 | 0.381746406553 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65673E-04 |
| R/G | 31198 |
Fn3-115 |
86 | rs751148256 |
0.6672 | -1.943 | 0.99 | N | 0.606 | 0.239 | 0.381746406553 | gnomAD-4.0.0 | 3.18228E-06 | None | None | None | None | N | None | 0 | 4.57373E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 31495 |
Fn3-117 |
88 | rs1329167679 |
0.9776 | None | 0.999 | D | 0.889 | 0.587 | 0.502254315933 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 31495 |
Fn3-117 |
88 | rs1329167679 |
0.9776 | None | 0.999 | D | 0.889 | 0.587 | 0.502254315933 | gnomAD-4.0.0 | 2.47939E-06 | None | None | None | None | N | None | 2.66944E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69573E-06 | 0 | 0 |
| V/A | 31794 |
Fn3-119 |
87 | rs2154145428 |
0.0808 | None | None | N | 0.252 | 0.129 | 0.132336055621 | gnomAD-4.0.0 | 3.18273E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.546E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 31794 |
Fn3-119 |
87 | rs1346238621 |
0.0875 | -0.538 | None | N | 0.182 | 0.085 | 0.115124310173 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| S/G | 31895 |
Fn3-120 |
89 | rs775090787 |
0.473 | -1.847 | 0.999 | D | 0.839 | 0.646 | 0.47185959272 | gnomAD-2.1.1 | 8.2E-06 | None | None | None | None | N | None | 0 | 2.95E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.69779E-04 |
| S/G | 31895 |
Fn3-120 |
89 | rs775090787 |
0.473 | -1.847 | 0.999 | D | 0.839 | 0.646 | 0.47185959272 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 31895 |
Fn3-120 |
89 | rs775090787 |
0.473 | -1.847 | 0.999 | D | 0.839 | 0.646 | 0.47185959272 | gnomAD-4.0.0 | 2.49938E-06 | None | None | None | None | N | None | 2.68327E-05 | 1.68793E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.61697E-05 |
| S/R | 31895 |
Fn3-120 |
89 | rs771633297 |
0.9977 | -0.849 | 1.0 | D | 0.815 | 0.699 | 0.166414681773 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| S/R | 31895 |
Fn3-120 |
89 | rs771633297 |
0.9977 | -0.849 | 1.0 | D | 0.815 | 0.699 | 0.166414681773 | gnomAD-4.0.0 | 4.147E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.44705E-06 | 0 | 0 |
| S/C | 31997 |
Fn3-121 |
89 | None | 0.1448 | None | 1.0 | D | 0.866 | 0.667 | 0.668525668689 | gnomAD-4.0.0 | 6.84264E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15942E-05 | 0 |
| S/G | 31997 |
Fn3-121 |
89 | rs763864462 |
0.1661 | -1.344 | 0.999 | D | 0.887 | 0.537 | 0.41219620536 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 1.78E-05 | 1.66168E-04 |
| S/G | 31997 |
Fn3-121 |
89 | rs763864462 |
0.1661 | -1.344 | 0.999 | D | 0.887 | 0.537 | 0.41219620536 | gnomAD-4.0.0 | 6.84264E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 5.20472E-04 | 2.69867E-06 | 3.47826E-05 | 1.65673E-05 |
| S/N | 31997 |
Fn3-121 |
89 | None | 0.6356 | None | 0.999 | D | 0.895 | 0.477 | 0.486920840936 | gnomAD-4.0.0 | 1.59162E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.8826E-05 | 0 | 0 | 0 | 0 |
| C/R | 32191 |
Fn3-122 |
87 | None | 0.322 | None | 0.999 | N | 0.836 | 0.357 | 0.674546049349 | gnomAD-4.0.0 | 2.05262E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69838E-06 | 0 | 0 |
| L/V | 32486 |
Fn3-124 |
88 | rs769778547 |
0.1422 | -0.767 | 0.997 | N | 0.714 | 0.169 | 0.442160178816 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.33E-05 | None | 0 | 0 | 0 |
| L/V | 32486 |
Fn3-124 |
88 | rs769778547 |
0.1422 | -0.767 | 0.997 | N | 0.714 | 0.169 | 0.442160178816 | gnomAD-4.0.0 | 1.59606E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44155E-05 | 0 |
| A/S | 32687 |
Fn3-126 |
88 | rs2154140466 |
0.11 | None | 1.0 | N | 0.628 | 0.303 | 0.117506650769 | gnomAD-4.0.0 | 1.60337E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.88635E-06 | 0 | 0 |
| A/V | 32687 |
Fn3-126 |
88 | None | 0.1804 | None | 1.0 | N | 0.669 | 0.374 | 0.38225645794 | gnomAD-4.0.0 | 2.05903E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70652E-06 | 0 | 0 |
| S/R | 32984 |
Fn3-128 |
89 | None | 0.9953 | None | 0.998 | N | 0.861 | 0.594 | 0.497152477365 | gnomAD-4.0.0 | 6.84894E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00471E-07 | 0 | 0 |
| R/C | 33085 |
Fn3-129 |
88 | rs748626206 |
0.2663 | -1.217 | 1.0 | N | 0.765 | 0.308 | 0.548188646194 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.55E-05 | None | 0 | 8.92E-06 | 0 |
| R/C | 33085 |
Fn3-129 |
88 | rs748626206 |
0.2663 | -1.217 | 1.0 | N | 0.765 | 0.308 | 0.548188646194 | gnomAD-4.0.0 | 1.16347E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51965E-05 | None | 0 | 0 | 4.49813E-06 | 8.12103E-05 | 6.62822E-05 |
| R/H | 33085 |
Fn3-129 |
88 | rs777035261 |
0.2296 | -1.83 | 1.0 | N | 0.763 | 0.382 | None | gnomAD-2.1.1 | 4.3E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 5.13E-05 | None | 6.56E-05 | None | 0 | 6.28E-05 | 0 |
| R/H | 33085 |
Fn3-129 |
88 | rs777035261 |
0.2296 | -1.83 | 1.0 | N | 0.763 | 0.382 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 2.07297E-04 | 0 |
| R/H | 33085 |
Fn3-129 |
88 | rs777035261 |
0.2296 | -1.83 | 1.0 | N | 0.763 | 0.382 | None | gnomAD-4.0.0 | 7.50092E-05 | None | None | None | None | N | None | 0 | 1.66761E-05 | None | 0 | 0 | None | 0 | 0 | 8.81719E-05 | 8.79121E-05 | 1.28119E-04 |
| S/R | 33479 |
Fn3-131 |
88 | rs775974075 |
0.9928 | -0.689 | 1.0 | D | 0.877 | 0.711 | 0.545519808136 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| S/R | 33479 |
Fn3-131 |
88 | rs775974075 |
0.9928 | -0.689 | 1.0 | D | 0.877 | 0.711 | 0.545519808136 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85858E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.