Structural position:

  • Domain Type: Fn3
  • Aligned Position: 123
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
T/N 15746 Fn3-1 90 rs750298764 0.5876 -1.144 0.999 N 0.799 0.289 0.455448229734 gnomAD-2.1.1 7.16E-06 None None None None N None 0 5.66E-05 None 0 0 None 0 None 0 0 0
T/N 15746 Fn3-1 90 rs750298764 0.5876 -1.144 0.999 N 0.799 0.289 0.455448229734 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.57E-05 0 0 0 None 0 0 0 0 0
T/N 15746 Fn3-1 90 rs750298764 0.5876 -1.144 0.999 N 0.799 0.289 0.455448229734 gnomAD-4.0.0 2.56574E-06 None None None None N None 0 3.39363E-05 None 0 0 None 0 0 0 0 0
T/S 15746 Fn3-1 90 rs750298764 0.3886 -1.258 0.997 N 0.683 0.195 0.222439326576 gnomAD-2.1.1 4.03E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
T/S 15746 Fn3-1 90 rs750298764 0.3886 -1.258 0.997 N 0.683 0.195 0.222439326576 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/S 15746 Fn3-1 90 rs750298764 0.3886 -1.258 0.997 N 0.683 0.195 0.222439326576 gnomAD-4.0.0 2.56574E-06 None None None None N None 1.69394E-05 0 None 0 0 None 0 0 2.39661E-06 0 0
I/S 15948 Fn3-3 90 rs767552822 0.2856 -1.458 0.003 N 0.592 0.138 0.52437609879 gnomAD-2.1.1 4.18E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.29E-06 0
I/S 15948 Fn3-3 90 rs767552822 0.2856 -1.458 0.003 N 0.592 0.138 0.52437609879 gnomAD-4.0.0 1.60645E-06 None None None None N None 0 0 None 0 0 None 0 0 2.88118E-06 0 0
V/I 16143 Fn3-4 89 rs2057207422 0.0751 None None N 0.147 0.096 0.134241683229 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 16143 Fn3-4 89 rs2057207422 0.0751 None None N 0.147 0.096 0.134241683229 gnomAD-4.0.0 6.58241E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47258E-05 0 0
P/A 16243 Fn3-5 89 rs72677242 0.0791 None 0.06 N 0.311 0.278 0.15556083564 gnomAD-4.0.0 1.40451E-06 None None None None N None 3.04414E-05 0 None 0 0 None 0 0 9.16288E-07 0 0
P/H 16243 Fn3-5 89 rs1176398842 0.5463 None 0.999 D 0.763 0.284 0.465633601861 gnomAD-4.0.0 7.02463E-07 None None None None N None 0 0 None 0 2.63685E-05 None 0 0 0 0 0
P/L 16243 Fn3-5 89 rs1176398842 0.2295 -0.132 0.919 N 0.674 0.291 0.518312163451 gnomAD-2.1.1 8.96E-06 None None None None N None 4.9E-05 0 None 0 0 None 0 None 0 1.04E-05 0
P/L 16243 Fn3-5 89 rs1176398842 0.2295 -0.132 0.919 N 0.674 0.291 0.518312163451 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 1.95695E-04 None 0 0 0 0 0
P/L 16243 Fn3-5 89 rs1176398842 0.2295 -0.132 0.919 N 0.674 0.291 0.518312163451 gnomAD-4.0.0 6.3479E-06 None None None None N None 0 0 None 0 2.32374E-05 None 0 0 6.90228E-06 0 1.63698E-05
P/S 16243 Fn3-5 89 rs72677242 0.2322 -0.517 0.307 N 0.333 0.203 None gnomAD-2.1.1 3.79376E-03 None None None None N None 1.46513E-04 4.57167E-04 None 1.80582E-03 0 None 5.12013E-04 None 1.52761E-02 4.67743E-03 2.10902E-03
P/S 16243 Fn3-5 89 rs72677242 0.2322 -0.517 0.307 N 0.333 0.203 None gnomAD-3.1.2 3.10817E-03 None None None None N None 4.83E-05 1.97031E-04 0 2.01845E-03 0 None 1.5867E-02 3.16456E-03 4.15292E-03 1.03691E-03 1.91205E-03
P/S 16243 Fn3-5 89 rs72677242 0.2322 -0.517 0.307 N 0.333 0.203 None 1000 genomes 1.59744E-03 None None None None N None 0 1.4E-03 None None 0 6E-03 None None None 1E-03 None
P/S 16243 Fn3-5 89 rs72677242 0.2322 -0.517 0.307 N 0.333 0.203 None gnomAD-4.0.0 2.45184E-03 None None None None N None 4.03356E-05 4.27748E-04 None 1.24258E-03 0 None 1.54746E-02 3.33444E-04 2.30838E-03 5.89146E-04 1.88111E-03
P/T 16243 Fn3-5 89 None 0.1896 -0.517 0.851 N 0.503 0.233 None gnomAD-2.1.1 3.63E-05 None None None None N None 0 3.62E-05 None 0 0 None 0 None 0 7.37E-05 0
P/T 16243 Fn3-5 89 None 0.1896 -0.517 0.851 N 0.503 0.233 None gnomAD-3.1.2 1.98E-05 None None None None N None 0 0 0 0 0 None 0 0 4.42E-05 0 0
P/T 16243 Fn3-5 89 None 0.1896 -0.517 0.851 N 0.503 0.233 None gnomAD-4.0.0 1.04071E-04 None None None None N None 0 1.86047E-05 None 0 0 None 0 0 1.39744E-04 0 1.63634E-05
A/S 16439 Fn3-6 89 rs759710792 0.0924 -1.069 0.024 N 0.491 0.074 0.110078149338 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
A/S 16439 Fn3-6 89 rs759710792 0.0924 -1.069 0.024 N 0.491 0.074 0.110078149338 gnomAD-3.1.2 6.59E-06 None None None None N None 0 6.57E-05 0 0 0 None 0 0 0 0 0
A/S 16439 Fn3-6 89 rs759710792 0.0924 -1.069 0.024 N 0.491 0.074 0.110078149338 gnomAD-4.0.0 1.2405E-06 None None None None N None 0 1.67112E-05 None 0 0 None 0 0 8.4802E-07 0 0
A/T 16439 Fn3-6 89 rs759710792 0.1133 -0.857 0.483 N 0.584 0.144 0.203808441222 gnomAD-2.1.1 8.08E-06 None None None None N None 0 5.82E-05 None 0 0 None 0 None 0 0 0
A/T 16439 Fn3-6 89 rs759710792 0.1133 -0.857 0.483 N 0.584 0.144 0.203808441222 gnomAD-4.0.0 1.36945E-06 None None None None N None 0 4.48189E-05 None 0 0 None 0 0 0 0 0
S/L 16539 Fn3-7 90 rs1037901670 0.1939 None 0.049 N 0.363 0.095 0.296679040009 gnomAD-4.0.0 3.19513E-06 None None None None N None 5.69671E-05 0 None 0 0 None 0 0 0 0 3.03711E-05
P/T 16639 Fn3-8 89 None 0.2165 None 0.972 N 0.814 0.278 0.33835085245 gnomAD-4.0.0 1.20037E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31256E-06 0 0
I/V 16739 Fn3-9 89 rs1553698265 0.0797 None None N 0.212 0.064 0.21737058555 gnomAD-4.0.0 1.59395E-06 None None None None N None 5.67472E-05 0 None 0 0 None 0 0 0 0 0
P/A 16840 Fn3-10 90 None 0.2417 None 0.539 N 0.709 0.255 0.226586394389 gnomAD-4.0.0 6.84674E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99868E-07 0 0
P/L 16840 Fn3-10 90 None 0.6672 None 0.891 N 0.901 0.336 0.483891081108 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/P 17135 Fn3-12 89 rs756515794 0.9531 -1.28 1.0 N 0.922 0.494 0.72014139575 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.62E-05 None 0 None 0 0 0
L/P 17135 Fn3-12 89 rs756515794 0.9531 -1.28 1.0 N 0.922 0.494 0.72014139575 gnomAD-4.0.0 1.59318E-06 None None None None N None 0 0 None 0 2.78505E-05 None 0 0 0 0 0
A/P 17236 Fn3-13 90 rs1208923941 0.1558 -0.272 0.001 N 0.223 0.151 0.115124310173 gnomAD-2.1.1 4.09E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.06E-06 0
A/P 17236 Fn3-13 90 rs1208923941 0.1558 -0.272 0.001 N 0.223 0.151 0.115124310173 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/P 17236 Fn3-13 90 rs1208923941 0.1558 -0.272 0.001 N 0.223 0.151 0.115124310173 gnomAD-4.0.0 3.73511E-06 None None None None N None 0 0 None 0 0 None 0 0 5.10619E-06 0 0
A/T 17236 Fn3-13 90 None 0.1854 None 0.003 N 0.241 0.097 0.101711395817 gnomAD-4.0.0 2.06259E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70973E-06 0 0
A/V 17236 Fn3-13 90 rs1041202552 0.2223 None None N 0.246 0.09 0.176091768786 gnomAD-4.0.0 4.83036E-06 None None None None N None 0 0 None 0 0 None 0 0 8.69711E-06 0 0
P/S 17558 Fn3-15 89 rs374845620 0.3434 -0.809 1.0 N 0.851 0.327 None gnomAD-2.1.1 4.16E-06 None None None None I None 6.61E-05 0 None 0 0 None 0 None 0 0 0
P/S 17558 Fn3-15 89 rs374845620 0.3434 -0.809 1.0 N 0.851 0.327 None gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/K 17658 Fn3-16 90 rs1576367047 0.9335 None 0.999 N 0.853 0.37 0.36893422563 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/K 17658 Fn3-16 90 rs1576367047 0.9335 None 0.999 N 0.853 0.37 0.36893422563 gnomAD-4.0.0 6.57955E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4721E-05 0 0
T/S 17658 Fn3-16 90 None 0.3867 None 0.997 N 0.754 0.202 0.144782658237 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 17851 Fn3-17 88 rs1458259896 0.1144 None 0.001 N 0.373 0.208 0.296329037015 gnomAD-4.0.0 2.74079E-06 None None None None N None 0 0 None 0 0 None 0 1.73853E-04 2.70037E-06 0 0
I/V 17851 Fn3-17 88 rs1472380264 0.0931 -1.036 0.001 N 0.265 0.082 0.218845423259 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 3.32E-05 None 0 0 0
I/V 17851 Fn3-17 88 rs1472380264 0.0931 -1.036 0.001 N 0.265 0.082 0.218845423259 gnomAD-4.0.0 1.59628E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.44417E-05 0
P/R 17951 Fn3-18 90 None 0.7708 None 0.998 N 0.873 0.397 0.466571191598 gnomAD-4.0.0 1.60174E-06 None None None None I None 0 0 None 0 0 None 0 0 2.87853E-06 0 0
P/T 18260 Fn3-20 95 None 0.1554 None 0.986 N 0.643 0.271 0.355242300401 gnomAD-4.0.0 1.59858E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87467E-06 0 0
T/I 18363 Fn3-21 92 rs1275266098 0.1271 -0.505 0.047 N 0.475 0.111 0.167679373172 gnomAD-2.1.1 7.16E-06 None None None None N None 0 0 None 9.68E-05 0 None 0 None 0 7.84E-06 0
T/I 18363 Fn3-21 92 rs1275266098 0.1271 -0.505 0.047 N 0.475 0.111 0.167679373172 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/I 18363 Fn3-21 92 rs1275266098 0.1271 -0.505 0.047 N 0.475 0.111 0.167679373172 gnomAD-4.0.0 3.10026E-06 None None None None N None 0 0 None 3.38043E-05 0 None 0 0 3.39179E-06 0 0
T/R 18363 Fn3-21 92 None 0.2637 None None N 0.234 0.169 0.225215365344 gnomAD-4.0.0 2.73832E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59924E-06 0 0
T/S 18567 Fn3-22 89 rs773703444 0.5719 -0.805 0.997 N 0.675 0.162 0.208816687407 gnomAD-2.1.1 4.3E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.36E-06 0
T/S 18567 Fn3-22 89 rs773703444 0.5719 -0.805 0.997 N 0.675 0.162 0.208816687407 gnomAD-4.0.0 1.65949E-06 None None None None N None 0 0 None 0 0 None 0 0 2.96665E-06 0 0
S/G 18873 Fn3-24 90 rs1212401338 0.4132 -0.915 0.997 N 0.768 0.211 0.400613892164 gnomAD-2.1.1 1.17E-05 None None None None N None 0 0 None 0 1.37382E-04 None 0 None 0 0 0
S/G 18873 Fn3-24 90 rs1212401338 0.4132 -0.915 0.997 N 0.768 0.211 0.400613892164 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.93949E-04 None 0 0 0 0 0
S/G 18873 Fn3-24 90 rs1212401338 0.4132 -0.915 0.997 N 0.768 0.211 0.400613892164 gnomAD-4.0.0 2.65483E-06 None None None None N None 0 0 None 0 6.93577E-05 None 0 0 0 1.43563E-05 0
S/N 18873 Fn3-24 90 rs2154191135 0.9394 None 0.997 D 0.824 0.351 0.456462010053 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 3.16456E-03 0 0 0
P/S 18977 Fn3-25 94 rs750056302 0.4013 -2.026 1.0 N 0.92 0.293 0.323886383625 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/S 18977 Fn3-25 94 rs750056302 0.4013 -2.026 1.0 N 0.92 0.293 0.323886383625 gnomAD-4.0.0 1.59221E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8601E-06 0 0
T/A 19272 Fn3-27 90 None 0.2537 None 0.997 N 0.703 0.269 0.204665344411 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/I 19272 Fn3-27 90 rs1049715521 0.4695 None 0.999 N 0.886 0.355 0.423119698836 gnomAD-4.0.0 5.66484E-06 None None None None N None 0 0 None 0 0 None 0 0 6.45084E-06 1.24772E-05 0
C/F 19373 Fn3-28 90 None 0.6125 None 0.981 N 0.731 0.256 0.630592674211 gnomAD-4.0.0 2.07463E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.60872E-05 0
C/R 19373 Fn3-28 90 None 0.8043 None 0.828 N 0.683 0.255 0.570965073944 gnomAD-4.0.0 1.62759E-06 None None None None N None 5.86923E-05 0 None 0 0 None 0 0 0 0 0
S/C 19568 Fn3-29 90 rs1465396608 0.5052 -0.323 1.0 N 0.797 0.486 0.535439087667 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
S/C 19568 Fn3-29 90 rs1465396608 0.5052 -0.323 1.0 N 0.797 0.486 0.535439087667 gnomAD-4.0.0 1.59417E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43678E-05 0
P/L 19668 Fn3-30 90 rs794729465 0.2196 -0.468 0.998 N 0.795 0.359 0.688008359126 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
P/L 19668 Fn3-30 90 rs794729465 0.2196 -0.468 0.998 N 0.795 0.359 0.688008359126 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 19668 Fn3-30 90 rs794729465 0.2196 -0.468 0.998 N 0.795 0.359 0.688008359126 gnomAD-4.0.0 2.23151E-05 None None None None N None 0 0 None 0 0 None 0 0 2.9671E-05 1.09825E-05 0
P/Q 19668 Fn3-30 90 rs794729465 0.4068 None 0.998 N 0.733 0.373 0.634485840324 gnomAD-4.0.0 2.73751E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.47907E-05 1.65722E-05
P/S 19668 Fn3-30 90 None 0.2061 None 0.835 N 0.407 0.293 0.379366414296 gnomAD-4.0.0 1.36875E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79919E-06 0 0
T/I 19965 Fn3-32 89 rs372266703 0.3368 0.287 0.028 N 0.485 0.097 None gnomAD-2.1.1 1.08E-05 None None None None N None 1.24028E-04 0 None 0 0 None 0 None 0 0 0
T/I 19965 Fn3-32 89 rs372266703 0.3368 0.287 0.028 N 0.485 0.097 None gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
T/I 19965 Fn3-32 89 rs372266703 0.3368 0.287 0.028 N 0.485 0.097 None gnomAD-4.0.0 3.04514E-06 None None None None N None 5.24329E-05 0 None 0 0 None 0 0 0 0 0
S/F 20260 Fn3-34 90 None 0.9179 None 0.999 D 0.9 0.385 0.761728025676 gnomAD-4.0.0 1.59225E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8603E-06 0 0
S/G 20359 Fn3-35 89 rs762408700 0.0858 -1.228 0.627 N 0.343 0.119 0.173771789658 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.55E-05 0
S/G 20359 Fn3-35 89 rs762408700 0.0858 -1.228 0.627 N 0.343 0.119 0.173771789658 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 4.41E-05 0 0
S/G 20359 Fn3-35 89 rs762408700 0.0858 -1.228 0.627 N 0.343 0.119 0.173771789658 gnomAD-4.0.0 8.67898E-06 None None None None N None 0 0 None 0 0 None 0 0 1.10223E-05 0 1.60159E-05
T/I 20656 Fn3-37 88 rs1363633199 0.8066 None 0.999 N 0.898 0.363 0.314716216878 gnomAD-4.0.0 2.73722E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59833E-06 0 0
T/K 20656 Fn3-37 88 rs1363633199 0.9562 None 0.999 N 0.883 0.361 0.382087116544 gnomAD-4.0.0 6.84305E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65684E-05
S/G 20952 Fn3-39 89 rs769683530 0.244 -1.127 0.115 N 0.525 0.287 0.257786959452 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 9.95E-05 0 None 0 None 0 0 0
S/G 20952 Fn3-39 89 rs769683530 0.244 -1.127 0.115 N 0.525 0.287 0.257786959452 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/R 20952 Fn3-39 89 rs748109390 0.9964 -0.39 0.314 D 0.683 0.436 0.259761712551 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 9.95E-05 0 None 0 None 0 0 0
S/R 20952 Fn3-39 89 rs748109390 0.9964 -0.39 0.314 D 0.683 0.436 0.259761712551 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/R 20952 Fn3-39 89 rs748109390 0.9964 -0.39 0.314 D 0.683 0.436 0.259761712551 gnomAD-4.0.0 6.58033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47137E-05 0 0
P/L 21052 Fn3-40 90 None 0.2443 None 0.995 N 0.724 0.372 0.541692676538 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 3.66327E-05
L/P 21159 Fn3-41 96 None 0.7285 None 0.999 N 0.89 0.454 0.544346501278 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/V 21159 Fn3-41 96 rs1218951803 0.1506 -1.187 0.429 N 0.347 0.113 0.230578612272 gnomAD-2.1.1 4.23E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.44E-06 0
L/V 21159 Fn3-41 96 rs1218951803 0.1506 -1.187 0.429 N 0.347 0.113 0.230578612272 gnomAD-4.0.0 1.61256E-06 None None None None N None 0 0 None 0 0 None 0 0 2.89907E-06 0 0
V/I 21354 Fn3-42 89 None 0.0607 None None N 0.219 0.128 0.119812018005 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
S/A 21648 Fn3-44 90 rs765042066 0.3176 -0.398 0.994 N 0.689 0.241 0.258779203287 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/A 21648 Fn3-44 90 rs765042066 0.3176 -0.398 0.994 N 0.689 0.241 0.258779203287 gnomAD-4.0.0 1.59195E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43328E-05 0
S/F 21648 Fn3-44 90 rs761835878 0.9145 -0.541 0.999 N 0.853 0.37 0.724992724663 gnomAD-4.0.0 3.18386E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85974E-06 1.43324E-05 0
P/H 21748 Fn3-45 90 None 0.5201 None 0.998 N 0.737 0.348 0.435808882951 gnomAD-4.0.0 1.63916E-06 None None None None I None 0 0 None 0 2.79987E-05 None 0 0 0 0 0
P/L 21748 Fn3-45 90 rs1419714561 0.2575 -0.101 0.986 N 0.719 0.292 0.46682414995 gnomAD-2.1.1 4.18E-06 None None None None I None 0 2.99E-05 None 0 0 None 0 None 0 0 0
P/L 21748 Fn3-45 90 rs1419714561 0.2575 -0.101 0.986 N 0.719 0.292 0.46682414995 gnomAD-4.0.0 6.55662E-06 None None None None I None 0 9.40867E-05 None 0 0 None 0 0 0 0 0
P/S 21748 Fn3-45 90 rs202009606 0.2453 -0.395 0.953 N 0.578 0.235 None gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 21748 Fn3-45 90 rs202009606 0.2453 -0.395 0.953 N 0.578 0.235 None gnomAD-4.0.0 1.87987E-06 None None None None I None 4.03128E-05 0 None 0 0 None 0 0 0 0 0
P/L 21848 Fn3-46 92 rs1559520585 0.1506 None 0.001 N 0.609 0.277 0.245660935333 gnomAD-4.0.0 1.37214E-06 None None None None N None 0 0 None 0 2.53846E-05 None 0 0 0 0 1.66168E-05
P/T 21848 Fn3-46 92 None 0.1551 None 0.335 N 0.659 0.206 0.231873229951 gnomAD-4.0.0 1.59783E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8685E-06 0 0
T/I 22044 Fn3-47 89 rs1490431835 0.8244 None 0.518 N 0.703 0.376 0.354396617058 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/P 22044 Fn3-47 89 None 0.9075 None 0.938 N 0.651 0.205 0.370240404367 gnomAD-4.0.0 1.62513E-06 None None None None N None 0 0 None 0 0 None 0 0 2.90877E-06 0 0
A/T 22144 Fn3-48 90 rs183276016 0.1094 -0.606 0.614 N 0.514 0.137 None gnomAD-2.1.1 2.71673E-04 None None None None N None 3.72147E-04 5.66669E-04 None 0 0 None 0 None 0 3.5974E-04 1.40568E-04
A/T 22144 Fn3-48 90 rs183276016 0.1094 -0.606 0.614 N 0.514 0.137 None gnomAD-3.1.2 2.49878E-04 None None None None N None 2.17223E-04 5.23834E-04 0 0 0 None 0 0 2.79461E-04 0 9.56938E-04
A/T 22144 Fn3-48 90 rs183276016 0.1094 -0.606 0.614 N 0.514 0.137 None gnomAD-4.0.0 4.64334E-04 None None None None N None 2.13738E-04 5.33707E-04 None 0 4.47207E-05 None 0 0 5.7229E-04 1.09796E-05 3.68483E-04
V/A 22246 Fn3-49 91 None 0.7568 None 0.441 N 0.676 0.233 0.357313475932 gnomAD-4.0.0 1.60916E-06 None None None None N None 0 0 None 0 0 None 0 0 2.89971E-06 0 0
V/M 22246 Fn3-49 91 rs1393150545 0.6445 -0.63 0.988 N 0.662 0.182 0.432716982437 gnomAD-2.1.1 8.15E-06 None None None None N None 0 0 None 0 5.63E-05 None 0 None 0 9.02E-06 0
V/M 22246 Fn3-49 91 rs1393150545 0.6445 -0.63 0.988 N 0.662 0.182 0.432716982437 gnomAD-4.0.0 1.78752E-05 None None None None N None 3.00174E-05 0 None 0 2.53601E-05 None 0 0 2.07814E-05 0 1.66583E-05
I/F 22537 Fn3-51 87 None 0.1981 None 0.868 N 0.724 0.105 0.531629458225 gnomAD-4.0.0 6.84391E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99664E-07 0 0
I/L 22537 Fn3-51 87 rs2047230730 0.1177 None 0.001 N 0.215 0.08 0.347659731818 gnomAD-4.0.0 2.05317E-06 None None None None N None 0 0 None 0 0 None 1.87484E-05 0 1.79933E-06 0 0
I/T 22537 Fn3-51 87 None 0.3556 None 0.791 N 0.715 0.263 0.640464653361 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/L 22732 Fn3-52 90 rs727505352 0.8489 0.454 0.915 N 0.713 0.45 0.590137622951 gnomAD-2.1.1 1.49507E-04 None None None None N None 0 9.61875E-04 None 0 1.11782E-04 None 3.31E-05 None 0 0 1.66889E-04
S/L 22732 Fn3-52 90 rs727505352 0.8489 0.454 0.915 N 0.713 0.45 0.590137622951 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
S/L 22732 Fn3-52 90 rs727505352 0.8489 0.454 0.915 N 0.713 0.45 0.590137622951 gnomAD-4.0.0 3.59926E-05 None None None None N None 6.68413E-05 6.18398E-04 None 0 8.93256E-05 None 0 0 3.3943E-06 4.40937E-05 6.41355E-05
P/S 22832 Fn3-53 90 None 0.2091 None 0.851 N 0.641 0.209 0.27479166964 gnomAD-4.0.0 1.36896E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99703E-07 1.16007E-05 0
S/N 22931 Fn3-54 91 rs201567815 0.1265 -0.997 0.501 N 0.678 0.196 None gnomAD-2.1.1 6.90573E-04 None None None None N None 0 0 None 0 4.14164E-04 None 0 None 4.91777E-03 3.77798E-04 1.98638E-03
S/N 22931 Fn3-54 91 rs201567815 0.1265 -0.997 0.501 N 0.678 0.196 None gnomAD-3.1.2 5E-04 None None None None N None 0 0 0 0 3.885E-04 None 5.56919E-03 0 2.20673E-04 0 0
S/N 22931 Fn3-54 91 rs201567815 0.1265 -0.997 0.501 N 0.678 0.196 None gnomAD-4.0.0 3.66063E-04 None None None None N None 0 0 None 0 1.6783E-03 None 5.59193E-03 0 9.3295E-05 0 7.69576E-04
S/R 22931 Fn3-54 91 rs794729484 0.4859 -0.675 0.877 N 0.757 0.279 0.18995819373 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
S/R 22931 Fn3-54 91 rs794729484 0.4859 -0.675 0.877 N 0.757 0.279 0.18995819373 gnomAD-3.1.2 3.29E-05 None None None None N None 1.20604E-04 0 0 0 0 None 0 0 0 0 0
S/R 22931 Fn3-54 91 rs794729484 0.4859 -0.675 0.877 N 0.757 0.279 0.18995819373 gnomAD-4.0.0 5.58301E-06 None None None None N None 1.0686E-04 0 None 0 0 None 0 0 0 0 1.60298E-05
S/Y 23128 Fn3-55 89 rs72646882 0.9496 -0.373 0.999 D 0.859 0.472 None gnomAD-2.1.1 7.51476E-04 None None None None N None 7.89583E-03 4.81123E-04 None 0 0 None 0 None 0 7.84E-06 1.40805E-04
S/Y 23128 Fn3-55 89 rs72646882 0.9496 -0.373 0.999 D 0.859 0.472 None gnomAD-3.1.2 2.24932E-03 None None None None N None 7.91697E-03 4.58595E-04 0 0 0 None 0 0 2.94E-05 0 2.39464E-03
S/Y 23128 Fn3-55 89 rs72646882 0.9496 -0.373 0.999 D 0.859 0.472 None 1000 genomes 1.39776E-03 None None None None N None 5.3E-03 0 None None 0 0 None None None 0 None
S/Y 23128 Fn3-55 89 rs72646882 0.9496 -0.373 0.999 D 0.859 0.472 None gnomAD-4.0.0 4.15914E-04 None None None None N None 7.90688E-03 4.83349E-04 None 0 0 None 0 3.30579E-04 3.39131E-06 1.09849E-05 6.72495E-04
A/S 23228 Fn3-56 90 None 0.1003 None 0.001 N 0.283 0.051 0.0954503805726 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 23330 Fn3-57 91 rs1211020644 0.4777 -2.885 0.682 N 0.76 0.254 0.665944241059 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/T 23330 Fn3-57 91 rs1211020644 0.4777 -2.885 0.682 N 0.76 0.254 0.665944241059 gnomAD-4.0.0 1.59211E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4339E-05 0
S/C 23619 Fn3-59 88 None 0.2227 None 0.997 N 0.713 0.419 0.384252928164 gnomAD-4.0.0 6.84391E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99588E-07 0 0
S/G 23619 Fn3-59 88 rs372823646 0.2509 -1.275 0.792 N 0.599 0.234 None gnomAD-2.1.1 1.79E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.13E-05 1.40805E-04
S/G 23619 Fn3-59 88 rs372823646 0.2509 -1.275 0.792 N 0.599 0.234 None gnomAD-3.1.2 3.94E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 7.35E-05 0 0
S/G 23619 Fn3-59 88 rs372823646 0.2509 -1.275 0.792 N 0.599 0.234 None gnomAD-4.0.0 4.89694E-05 None None None None N None 1.33522E-05 0 None 0 0 None 0 0 6.44277E-05 0 3.20328E-05
P/T 23915 Fn3-61 90 None 0.1011 None 0.376 N 0.494 0.1 0.226586394389 gnomAD-4.0.0 1.59179E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02444E-05
P/L 24014 Fn3-62 91 None 0.156 None 0.933 N 0.729 0.235 0.415690173769 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 24014 Fn3-62 91 rs754034457 0.1461 -1.691 0.051 N 0.275 0.153 0.0954503805726 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/S 24014 Fn3-62 91 rs754034457 0.1461 -1.691 0.051 N 0.275 0.153 0.0954503805726 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 24014 Fn3-62 91 rs754034457 0.1461 -1.691 0.051 N 0.275 0.153 0.0954503805726 gnomAD-4.0.0 2.60331E-05 None None None None N None 0 1.66739E-05 None 0 0 None 0 0 3.39105E-05 0 1.60123E-05
S/T 24211 Fn3-63 90 rs758212615 0.1244 -0.441 0.997 N 0.723 0.228 0.365120060079 gnomAD-2.1.1 5.42E-05 None None None None N None 0 3.47021E-04 None 0 0 None 1.50693E-04 None 0 1.2E-05 0
S/T 24211 Fn3-63 90 rs758212615 0.1244 -0.441 0.997 N 0.723 0.228 0.365120060079 gnomAD-3.1.2 3.95E-05 None None None None N None 0 3.27697E-04 0 0 0 None 0 0 0 2.07297E-04 0
S/T 24211 Fn3-63 90 rs758212615 0.1244 -0.441 0.997 N 0.723 0.228 0.365120060079 gnomAD-4.0.0 1.73517E-05 None None None None N None 0 2.69146E-04 None 0 0 None 0 3.5868E-04 4.43526E-06 5.82954E-05 6.95217E-05
T/A 24311 Fn3-64 90 rs56201325 0.0524 -1.171 None N 0.167 0.054 None gnomAD-2.1.1 4.04628E-03 None None None None N None 7.86164E-04 1.17069E-03 None 0 0 None 1.69022E-04 None 8.49455E-03 6.39959E-03 5.01145E-03
T/A 24311 Fn3-64 90 rs56201325 0.0524 -1.171 None N 0.167 0.054 None gnomAD-3.1.2 3.44479E-03 None None None None N None 7.72164E-04 1.44149E-03 0 0 0 None 7.34187E-03 0 5.66193E-03 0 3.34608E-03
T/A 24311 Fn3-64 90 rs56201325 0.0524 -1.171 None N 0.167 0.054 None 1000 genomes 7.98722E-04 None None None None N None 0 1.4E-03 None None 0 3E-03 None None None 0 None
T/A 24311 Fn3-64 90 rs56201325 0.0524 -1.171 None N 0.167 0.054 None gnomAD-4.0.0 4.24777E-03 None None None None N None 8.13919E-04 1.27282E-03 None 0 0 None 8.43128E-03 4.97678E-04 5.01925E-03 1.21905E-04 3.82342E-03
T/N 24311 Fn3-64 90 None 0.1188 None 0.001 N 0.18 0.145 0.258779203287 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
T/P 24311 Fn3-64 90 None 0.0596 None 0.475 N 0.579 0.099 0.151104730317 gnomAD-4.0.0 6.86634E-07 None None None None N None 0 0 None 0 0 None 0 1.74398E-04 0 0 0
V/F 24413 Fn3-65 91 None 0.6036 None 0.931 N 0.665 0.325 0.664136802156 gnomAD-4.0.0 1.59214E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85953E-06 0 0
T/I 24607 Fn3-66 89 rs1286853195 0.4435 None 1.0 N 0.835 0.386 0.384752662912 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/I 24607 Fn3-66 89 rs1286853195 0.4435 None 1.0 N 0.835 0.386 0.384752662912 gnomAD-4.0.0 2.02998E-06 None None None None N None 0 0 None 0 0 None 0 0 2.40993E-06 0 0
L/P 24703 Fn3-67 88 None 0.87 None 1.0 N 0.855 0.434 0.660644780661 gnomAD-4.0.0 1.36885E-06 None None None None N None 0 0 None 0 2.5296E-05 None 0 0 8.99607E-07 0 0
S/C 25096 Fn3-70 91 None 0.2038 None 1.0 N 0.848 0.269 0.250039746154 gnomAD-4.0.0 1.59171E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85919E-06 0 0
S/C 25293 Fn3-71 90 rs186240800 0.3114 -0.393 0.049 D 0.581 0.425 None gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 5.61E-05 None 0 None 0 0 0
S/C 25293 Fn3-71 90 rs186240800 0.3114 -0.393 0.049 D 0.581 0.425 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 1.93498E-04 None 0 0 0 0 0
S/C 25293 Fn3-71 90 rs186240800 0.3114 -0.393 0.049 D 0.581 0.425 None 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 1E-03 0 None None None 0 None
S/C 25293 Fn3-71 90 rs186240800 0.3114 -0.393 0.049 D 0.581 0.425 None gnomAD-4.0.0 8.97098E-06 None None None None I None 0 0 None 0 1.70283E-04 None 0 0 0 0 0
P/S 25393 Fn3-72 90 rs1005590673 0.1195 None 0.18 N 0.372 0.164 0.165133752707 gnomAD-4.0.0 3.18885E-06 None None None None N None 0 4.57917E-05 None 0 0 None 0 0 0 0 0
V/I 25495 Fn3-73 91 rs773127796 0.0659 -0.596 0.003 N 0.169 0.052 0.400899426204 gnomAD-2.1.1 1.62802E-04 None None None None N None 0 0 None 0 0 None 1.21855E-03 None 0 6.35E-05 0
V/I 25495 Fn3-73 91 rs773127796 0.0659 -0.596 0.003 N 0.169 0.052 0.400899426204 gnomAD-3.1.2 4.6E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 1.0352E-03 0
V/I 25495 Fn3-73 91 rs773127796 0.0659 -0.596 0.003 N 0.169 0.052 0.400899426204 gnomAD-4.0.0 8.56074E-05 None None None None N None 0 0 None 0 0 None 0 0 2.88358E-05 1.11089E-03 4.8097E-05
T/A 25689 Fn3-74 89 rs1360848714 0.2542 -1.078 0.565 N 0.541 0.286 0.17258766438 gnomAD-2.1.1 7.15E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
T/A 25689 Fn3-74 89 rs1360848714 0.2542 -1.078 0.565 N 0.541 0.286 0.17258766438 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
T/A 25689 Fn3-74 89 rs1360848714 0.2542 -1.078 0.565 N 0.541 0.286 0.17258766438 gnomAD-4.0.0 2.47952E-06 None None None None N None 4.00652E-05 0 None 0 0 None 0 0 8.47774E-07 0 0
T/I 25689 Fn3-74 89 None 0.3201 None 0.055 N 0.439 0.201 0.265010934533 gnomAD-4.0.0 1.36877E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99628E-07 1.15993E-05 0
T/N 25689 Fn3-74 89 rs369081503 0.4625 -0.809 0.989 N 0.683 0.286 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
T/N 25689 Fn3-74 89 rs369081503 0.4625 -0.809 0.989 N 0.683 0.286 None gnomAD-4.0.0 1.02658E-05 None None None None N None 0 0 None 0 0 None 0 0 1.16952E-05 0 3.314E-05
L/P 25785 Fn3-75 88 rs1385070612 0.8486 -1.285 1.0 N 0.87 0.471 0.723938039073 gnomAD-2.1.1 8.09E-06 None None None None N None 0 2.91E-05 None 0 0 None 0 None 0 8.96E-06 0
L/P 25785 Fn3-75 88 rs1385070612 0.8486 -1.285 1.0 N 0.87 0.471 0.723938039073 gnomAD-4.0.0 5.47675E-06 None None None None N None 0 2.23804E-05 None 0 0 None 0 0 6.29856E-06 0 0
L/R 25785 Fn3-75 88 None 0.8744 None 0.999 N 0.841 0.498 0.768798656172 gnomAD-4.0.0 3.42297E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59917E-06 1.1606E-05 0
S/A 25979 Fn3-76 90 None 0.4676 None 0.994 N 0.627 0.297 0.373173300195 gnomAD-4.0.0 1.59169E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
S/F 25979 Fn3-76 90 None 0.9842 None 0.999 N 0.853 0.394 0.632343933599 gnomAD-4.0.0 1.59171E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85945E-06 0 0
N/H 26079 Fn3-77 90 rs1331149411 0.1347 None 0.412 N 0.453 0.082 0.229924730088 gnomAD-4.0.0 1.36859E-06 None None None None N None 0 2.23614E-05 None 0 0 None 0 0 8.99588E-07 0 0
A/G 26475 Fn3-80 90 rs1706007740 0.1646 None 0.094 N 0.298 0.206 0.315609569513 gnomAD-4.0.0 1.59212E-06 None None None None I None 0 0 None 0 2.77346E-05 None 0 0 0 0 0
A/P 26475 Fn3-80 90 rs1245328296 0.0795 0.013 None N 0.178 0.2 0.156986980423 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/P 26475 Fn3-80 90 rs1245328296 0.0795 0.013 None N 0.178 0.2 0.156986980423 gnomAD-4.0.0 1.3687E-06 None None None None I None 0 0 None 0 0 None 0 0 8.99536E-07 1.15945E-05 0
T/A 26771 Fn3-82 89 None 0.3808 None 0.986 N 0.66 0.49 0.309839678437 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
T/I 26771 Fn3-82 89 rs567184856 0.5784 0.181 1.0 N 0.903 0.466 0.389750110748 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
T/I 26771 Fn3-82 89 rs567184856 0.5784 0.181 1.0 N 0.903 0.466 0.389750110748 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07383E-04 0
T/I 26771 Fn3-82 89 rs567184856 0.5784 0.181 1.0 N 0.903 0.466 0.389750110748 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
T/I 26771 Fn3-82 89 rs567184856 0.5784 0.181 1.0 N 0.903 0.466 0.389750110748 gnomAD-4.0.0 2.56247E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.68053E-05 0
L/W 26867 Fn3-83 88 rs1038243734 0.8614 -1.688 1.0 D 0.849 0.693 0.821037014432 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
L/W 26867 Fn3-83 88 rs1038243734 0.8614 -1.688 1.0 D 0.849 0.693 0.821037014432 gnomAD-4.0.0 1.59172E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85933E-06 0 0
S/P 27061 Fn3-84 90 rs773739899 0.9877 -0.169 0.999 N 0.821 0.519 0.350524144436 gnomAD-2.1.1 8.09E-06 None None None None N None 0 0 None 0 1.11732E-04 None 0 None 0 0 0
S/P 27061 Fn3-84 90 rs773739899 0.9877 -0.169 0.999 N 0.821 0.519 0.350524144436 gnomAD-4.0.0 3.19036E-06 None None None None N None 0 0 None 0 5.54877E-05 None 0 0 0 0 0
V/A 27161 Fn3-85 90 rs761391019 0.1114 -1.819 0.006 N 0.389 0.136 0.337135696972 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/A 27161 Fn3-85 90 rs761391019 0.1114 -1.819 0.006 N 0.389 0.136 0.337135696972 gnomAD-4.0.0 6.15888E-06 None None None None N None 0 0 None 0 0 None 0 0 0 9.27558E-05 1.657E-05
V/E 27161 Fn3-85 90 rs761391019 0.335 -1.846 0.868 N 0.696 0.201 0.660217342666 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 1.12158E-04 None 0 None 0 0 0
V/E 27161 Fn3-85 90 rs761391019 0.335 -1.846 0.868 N 0.696 0.201 0.660217342666 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.93274E-04 None 0 0 0 0 0
V/E 27161 Fn3-85 90 rs761391019 0.335 -1.846 0.868 N 0.696 0.201 0.660217342666 gnomAD-4.0.0 4.33857E-06 None None None None N None 0 0 None 0 1.34036E-04 None 0 0 0 0 1.60143E-05
V/L 27161 Fn3-85 90 None 0.1687 None 0.006 N 0.313 0.042 0.191931220699 gnomAD-4.0.0 1.59191E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85892E-06 0 0
S/T 27260 Fn3-86 91 rs752173731 0.1075 -0.581 0.792 N 0.712 0.129 0.128392430309 gnomAD-2.1.1 8.05E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
S/T 27260 Fn3-86 91 rs752173731 0.1075 -0.581 0.792 N 0.712 0.129 0.128392430309 gnomAD-4.0.0 3.18286E-06 None None None None N None 0 4.57415E-05 None 0 0 None 0 0 0 0 0
S/F 27458 Fn3-87 90 rs1335006996 0.9415 -0.538 0.999 D 0.866 0.43 0.572964795716 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
S/F 27458 Fn3-87 90 rs1335006996 0.9415 -0.538 0.999 D 0.866 0.43 0.572964795716 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/P 27660 Fn3-89 91 rs1222575627 0.5751 -1.498 0.57 N 0.789 0.365 0.77589158586 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
L/P 27660 Fn3-89 91 rs1222575627 0.5751 -1.498 0.57 N 0.789 0.365 0.77589158586 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/P 27660 Fn3-89 91 rs1222575627 0.5751 -1.498 0.57 N 0.789 0.365 0.77589158586 gnomAD-4.0.0 1.23945E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69531E-06 0 0
L/Q 27660 Fn3-89 91 None 0.5257 None 0.303 N 0.727 0.353 0.796785688759 gnomAD-4.0.0 6.8424E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65684E-05
T/A 27854 Fn3-90 89 rs876658086 0.2921 -0.599 0.783 N 0.674 0.247 0.185906805712 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
T/A 27854 Fn3-90 89 rs876658086 0.2921 -0.599 0.783 N 0.674 0.247 0.185906805712 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/A 27854 Fn3-90 89 rs876658086 0.2921 -0.599 0.783 N 0.674 0.247 0.185906805712 gnomAD-4.0.0 6.57168E-06 None None None None N None 2.41336E-05 0 None 0 0 None 0 0 0 0 0
T/K 27854 Fn3-90 89 None 0.867 None 0.997 N 0.779 0.356 0.425148423609 gnomAD-4.0.0 1.59826E-06 None None None None N None 0 0 None 0 2.7767E-05 None 0 0 0 0 0
L/F 27950 Fn3-91 88 None 0.7014 None 0.998 N 0.815 0.221 0.370424759081 gnomAD-4.0.0 1.59216E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85927E-06 0 0
L/I 27950 Fn3-91 88 None 0.2209 None 0.811 N 0.663 0.077 0.237489013734 gnomAD-4.0.0 1.59216E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43382E-05 0
L/P 27950 Fn3-91 88 None 0.85 None 0.999 N 0.849 0.423 0.667319264289 gnomAD-4.0.0 2.05312E-06 None None None None N None 0 0 None 0 0 None 0 0 2.6987E-06 0 0
S/F 28143 Fn3-92 89 rs878971321 0.9087 None 0.981 N 0.789 0.404 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
S/F 28143 Fn3-92 89 rs878971321 0.9087 None 0.981 N 0.789 0.404 None gnomAD-4.0.0 6.57039E-06 None None None None N None 2.41266E-05 0 None 0 0 None 0 0 0 0 0
S/F 28243 Fn3-93 90 rs746193654 0.2502 -0.915 0.162 N 0.586 0.179 0.424549175451 gnomAD-2.1.1 8.05E-06 None None None None I None 0 5.79E-05 None 0 0 None 0 None 0 0 0
S/F 28243 Fn3-93 90 rs746193654 0.2502 -0.915 0.162 N 0.586 0.179 0.424549175451 gnomAD-4.0.0 2.05265E-06 None None None None I None 0 4.47207E-05 None 0 0 None 0 0 8.99465E-07 0 0
S/T 28243 Fn3-93 90 None 0.0838 None 0.006 N 0.334 0.06 0.0482279557977 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
S/Y 28243 Fn3-93 90 None 0.242 None 0.162 N 0.569 0.182 0.426551566703 gnomAD-4.0.0 6.84218E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99465E-07 0 0
S/P 28342 Fn3-94 91 None 0.1441 None 0.938 N 0.595 0.243 0.193865811164 gnomAD-4.0.0 1.59116E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
T/A 28639 Fn3-96 90 rs1198379778 0.0607 -1.15 None N 0.232 0.16 0.0297737177859 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
T/A 28639 Fn3-96 90 rs1198379778 0.0607 -1.15 None N 0.232 0.16 0.0297737177859 gnomAD-3.1.2 6.6E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/A 28639 Fn3-96 90 rs1198379778 0.0607 -1.15 None N 0.232 0.16 0.0297737177859 gnomAD-4.0.0 3.09977E-06 None None None None N None 0 0 None 0 0 None 0 0 4.23858E-06 0 0
T/N 28639 Fn3-96 90 rs1316337733 0.0978 -0.869 0.013 N 0.639 0.109 0.18995819373 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
T/N 28639 Fn3-96 90 rs1316337733 0.0978 -0.869 0.013 N 0.639 0.109 0.18995819373 gnomAD-4.0.0 1.5912E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8582E-06 0 0
T/P 28639 Fn3-96 90 None 0.0562 None None N 0.444 0.137 0.0297737177859 gnomAD-4.0.0 6.84204E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99465E-07 0 0
S/R 28739 Fn3-97 89 rs1468503993 0.5641 -0.636 0.047 N 0.644 0.09 0.132336055621 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
P/R 29326 Fn3-101 90 rs1450387071 0.3873 -0.584 0.087 N 0.67 0.307 0.336647302497 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/R 29326 Fn3-101 90 rs1450387071 0.3873 -0.584 0.087 N 0.67 0.307 0.336647302497 gnomAD-4.0.0 3.18235E-06 None None None None I None 0 0 None 0 0 None 0 0 5.71549E-06 0 0
P/S 29326 Fn3-101 90 rs1190882464 0.1411 -1.349 None N 0.419 0.105 0.0884992946249 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/S 29326 Fn3-101 90 rs1190882464 0.1411 -1.349 None N 0.419 0.105 0.0884992946249 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
V/D 29425 Fn3-102 91 None 0.2399 None 0.177 N 0.705 0.154 0.275215494804 gnomAD-4.0.0 3.18286E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71602E-06 0 0
V/F 29425 Fn3-102 91 rs1701721466 0.1884 None 0.177 N 0.758 0.03 0.235038932564 gnomAD-4.0.0 2.73695E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.63736E-05 0
S/Y 29622 Fn3-103 90 rs1274325104 0.9753 -0.563 0.999 D 0.873 0.466 0.695963169682 gnomAD-2.1.1 8.07E-06 None None None None N None 0 5.81E-05 None 0 0 None 0 None 0 0 0
S/Y 29622 Fn3-103 90 rs1274325104 0.9753 -0.563 0.999 D 0.873 0.466 0.695963169682 gnomAD-4.0.0 3.18379E-06 None None None None N None 0 4.57457E-05 None 0 0 None 0 0 0 0 0
P/A 29722 Fn3-104 90 None 0.0658 None 0.001 N 0.276 0.084 0.139678290688 gnomAD-4.0.0 2.06279E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70283E-06 0 0
P/Q 29722 Fn3-104 90 rs763050858 0.2967 -1.191 0.93 N 0.584 0.347 0.371344866733 gnomAD-2.1.1 4.13E-06 None None None None N None 0 0 None 0 0 None 3.38E-05 None 0 0 0
P/Q 29722 Fn3-104 90 rs763050858 0.2967 -1.191 0.93 N 0.584 0.347 0.371344866733 gnomAD-4.0.0 1.61136E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.45062E-05 0
P/S 29722 Fn3-104 90 None 0.1729 None 0.278 N 0.463 0.097 0.148003135375 gnomAD-4.0.0 2.75038E-06 None None None None N None 0 0 None 0 0 None 0 0 3.60378E-06 0 0
P/T 29722 Fn3-104 90 rs538120743 0.1209 -1.411 0.435 N 0.495 0.106 0.253726318573 gnomAD-2.1.1 3.7E-05 None None None None N None 0 2.05713E-04 None 0 0 None 3.36E-05 None 0 9E-06 0
P/T 29722 Fn3-104 90 rs538120743 0.1209 -1.411 0.435 N 0.495 0.106 0.253726318573 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 29722 Fn3-104 90 rs538120743 0.1209 -1.411 0.435 N 0.495 0.106 0.253726318573 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
P/T 29722 Fn3-104 90 rs538120743 0.1209 -1.411 0.435 N 0.495 0.106 0.253726318573 gnomAD-4.0.0 1.12034E-05 None None None None N None 0 1.17576E-04 None 0 0 None 0 0 6.79131E-06 3.32145E-05 0
M/R 29824 Fn3-105 91 rs764161774 0.5605 -1.388 0.991 N 0.756 0.388 0.635979805963 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
M/R 29824 Fn3-105 91 rs764161774 0.5605 -1.388 0.991 N 0.756 0.388 0.635979805963 gnomAD-4.0.0 8.2129E-06 None None None None N None 0 0 None 0 0 None 0 0 1.07953E-05 0 0
M/T 29824 Fn3-105 91 None 0.4178 None 0.915 N 0.686 0.334 0.662284845153 gnomAD-4.0.0 6.84408E-07 None None None None N None 0 0 None 0 0 None 1.87448E-05 0 0 0 0
I/T 30117 Fn3-107 88 rs1446752513 0.0808 None 0.008 N 0.438 0.171 0.400468435593 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/T 30117 Fn3-107 88 rs1446752513 0.0808 None 0.008 N 0.438 0.171 0.400468435593 gnomAD-4.0.0 4.95759E-06 None None None None N None 0 0 None 0 2.23105E-05 None 3.12432E-05 0 4.23794E-06 0 0
I/V 30117 Fn3-107 88 rs1241230315 0.0611 -1.227 0.001 N 0.222 0.09 0.269558022972 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
I/V 30117 Fn3-107 88 rs1241230315 0.0611 -1.227 0.001 N 0.222 0.09 0.269558022972 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 30117 Fn3-107 88 rs1241230315 0.0611 -1.227 0.001 N 0.222 0.09 0.269558022972 gnomAD-4.0.0 3.84357E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17879E-06 0 0
P/S 30413 Fn3-109 90 None 0.1244 None 0.953 N 0.609 0.236 0.232513804876 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
S/Y 30511 Fn3-110 90 None 0.6905 None 0.999 N 0.914 0.385 0.608970947243 gnomAD-4.0.0 1.36896E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79932E-06 0 0
I/T 30809 Fn3-112 91 rs976337472 0.1407 -1.598 None N 0.356 0.101 0.43656330218 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
I/T 30809 Fn3-112 91 rs976337472 0.1407 -1.598 None N 0.356 0.101 0.43656330218 gnomAD-4.0.0 1.59121E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85785E-06 0 0
V/M 30910 Fn3-113 90 rs1698264334 0.1666 None 0.002 N 0.489 0.13 0.181679512989 gnomAD-4.0.0 1.59119E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
M/I 31104 Fn3-114 89 rs745736147 0.3471 -0.421 0.146 N 0.423 0.074 0.317958651998 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
M/I 31104 Fn3-114 89 rs745736147 0.3471 -0.421 0.146 N 0.423 0.074 0.317958651998 gnomAD-4.0.0 1.59116E-06 None None None None N None 0 2.28634E-05 None 0 0 None 0 0 0 0 0
M/T 31104 Fn3-114 89 rs772169998 0.2381 -1.657 0.002 N 0.436 0.251 0.52133269049 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 2.98864E-04 0 None 0 None 0 0 0
M/T 31104 Fn3-114 89 rs772169998 0.2381 -1.657 0.002 N 0.436 0.251 0.52133269049 gnomAD-4.0.0 7.95553E-06 None None None None N None 0 0 None 1.43007E-04 0 None 0 0 5.71589E-06 0 0
A/G 31200 Fn3-115 88 None 0.2603 None 0.988 N 0.482 0.31 0.353761421236 gnomAD-4.0.0 1.36839E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79889E-06 0 0
A/T 31497 Fn3-117 90 rs1371205000 0.2316 -1.482 0.998 N 0.758 0.245 0.29527378943 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/T 31497 Fn3-117 90 rs1371205000 0.2316 -1.482 0.998 N 0.758 0.245 0.29527378943 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
A/T 31497 Fn3-117 90 rs1371205000 0.2316 -1.482 0.998 N 0.758 0.245 0.29527378943 gnomAD-4.0.0 2.56464E-06 None None None None N None 0 1.69549E-05 None 0 0 None 0 0 0 1.34081E-05 0
S/C 31599 Fn3-118 94 rs1456653211 0.178 -0.873 0.999 N 0.508 0.34 0.350746614512 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.665E-04
S/C 31599 Fn3-118 94 rs1456653211 0.178 -0.873 0.999 N 0.508 0.34 0.350746614512 gnomAD-4.0.0 1.59396E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.0281E-05
S/F 31599 Fn3-118 94 rs1456653211 0.6384 None 0.987 N 0.672 0.381 0.491387584038 gnomAD-4.0.0 1.59396E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86502E-06 0 0
S/T 31599 Fn3-118 94 rs376588396 0.1069 -0.759 0.126 N 0.405 0.079 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
A/T 31897 Fn3-120 91 rs2555815 0.1179 None 0.518 N 0.605 0.064 0.130388298395 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 31897 Fn3-120 91 rs2555815 0.1179 None 0.518 N 0.605 0.064 0.130388298395 gnomAD-4.0.0 2.63723E-06 None None None None N None 1.70975E-05 0 None 0 0 None 0 0 0 0 2.93341E-05
T/I 32193 Fn3-122 89 None 0.5707 None 1.0 N 0.856 0.349 0.369682402691 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
T/I 32291 Fn3-123 90 rs780461366 0.0755 0.101 None N 0.213 0.088 0.0611884634855 gnomAD-2.1.1 2.43E-05 None None None None N None 0 0 None 0 2.78303E-04 None 3.32E-05 None 0 0 0
T/I 32291 Fn3-123 90 rs780461366 0.0755 0.101 None N 0.213 0.088 0.0611884634855 gnomAD-3.1.2 6.62E-06 None None None None N None 0 6.6E-05 0 0 0 None 0 0 0 0 0
T/I 32291 Fn3-123 90 rs780461366 0.0755 0.101 None N 0.213 0.088 0.0611884634855 gnomAD-4.0.0 5.61178E-06 None None None None N None 0 1.67605E-05 None 0 1.34318E-04 None 0 0 0 1.10458E-05 1.61186E-05
T/S 32291 Fn3-123 90 rs1377452178 0.1826 -0.883 0.022 N 0.267 0.036 0.0297737177859 gnomAD-2.1.1 3.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.53E-05 0
T/S 32291 Fn3-123 90 rs1377452178 0.1826 -0.883 0.022 N 0.267 0.036 0.0297737177859 gnomAD-3.1.2 1.98E-05 None None None None N None 0 0 0 0 0 None 0 0 4.42E-05 0 0
T/S 32291 Fn3-123 90 rs1377452178 0.1826 -0.883 0.022 N 0.267 0.036 0.0297737177859 gnomAD-4.0.0 1.97597E-05 None None None None N None 0 0 None 0 0 None 0 0 4.41566E-05 0 0
S/F 32488 Fn3-124 90 None 0.9875 None 0.999 N 0.839 0.447 0.743508982932 gnomAD-4.0.0 1.23355E-05 None None None None N None 0 0 None 0 0 None 0 0 1.62055E-05 0 0
S/P 32488 Fn3-124 90 None 0.9909 None 0.999 N 0.789 0.483 0.360565625551 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
P/A 32588 Fn3-125 90 None 0.0707 None 0.002 N 0.442 0.129 0.16115917748 gnomAD-4.0.0 7.18103E-07 None None None None N None 0 0 None 0 0 None 0 0 9.32987E-07 0 0
P/L 32588 Fn3-125 90 rs1487598622 0.1045 -0.568 0.651 N 0.725 0.236 0.488548280593 gnomAD-2.1.1 6.05E-06 None None None None N None 0 0 None 0 8.51E-05 None 0 None 0 0 0
P/L 32588 Fn3-125 90 rs1487598622 0.1045 -0.568 0.651 N 0.725 0.236 0.488548280593 gnomAD-4.0.0 1.79193E-06 None None None None N None 0 0 None 0 3.05736E-05 None 0 0 0 0 0
P/S 32588 Fn3-125 90 None 0.1331 None 0.01 N 0.433 0.145 0.163833314356 gnomAD-4.0.0 1.43621E-06 None None None None N None 0 0 None 0 0 None 0 0 1.86597E-06 0 0
V/I 32689 Fn3-126 90 None 0.0935 None 0.214 N 0.147 0.153 0.390531646278 gnomAD-4.0.0 3.21222E-06 None None None None N None 0 0 None 0 2.77747E-05 None 1.89029E-05 0 0 0 0
S/Y 32884 Fn3-127 90 None 0.8274 None 0.999 N 0.879 0.455 0.659942566833 gnomAD-4.0.0 1.20033E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
V/E 33380 Fn3-130 91 rs1461056252 0.653 -1.019 0.966 N 0.713 0.36 0.698509492642 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/E 33380 Fn3-130 91 rs1461056252 0.653 -1.019 0.966 N 0.713 0.36 0.698509492642 gnomAD-4.0.0 7.96435E-06 None None None None N None 0 0 None 0 0 None 0 0 1.43032E-05 0 0
I/M 33481 Fn3-131 90 None 0.1286 None 0.938 N 0.743 0.054 0.308278614506 gnomAD-4.0.0 1.59165E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43308E-05 0
I/T 33481 Fn3-131 90 rs1464925577 0.1326 -2.554 0.007 N 0.552 0.133 0.382592752248 gnomAD-2.1.1 4.02E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
I/T 33481 Fn3-131 90 rs1464925577 0.1326 -2.554 0.007 N 0.552 0.133 0.382592752248 gnomAD-4.0.0 1.59165E-06 None None None None N None 5.65611E-05 0 None 0 0 None 0 0 0 0 0
P/A 33776 Fn3-132 88 rs746665837 0.0806 -1.556 0.998 N 0.811 0.295 0.305730143919 gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
P/A 33776 Fn3-132 88 rs746665837 0.0806 -1.556 0.998 N 0.811 0.295 0.305730143919 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/A 33776 Fn3-132 88 rs746665837 0.0806 -1.556 0.998 N 0.811 0.295 0.305730143919 gnomAD-4.0.0 5.57713E-06 None None None None N None 0 0 None 0 0 None 0 0 6.78048E-06 0 1.60092E-05
P/L 33776 Fn3-132 88 rs536357517 0.1984 -0.603 1.0 N 0.83 0.335 0.677900743141 gnomAD-2.1.1 8.03E-06 None None None None N None 1.29182E-04 0 None 0 0 None 0 None 0 0 0
P/L 33776 Fn3-132 88 rs536357517 0.1984 -0.603 1.0 N 0.83 0.335 0.677900743141 gnomAD-3.1.2 2.63E-05 None None None None N None 9.65E-05 0 0 0 0 None 0 0 0 0 0
P/L 33776 Fn3-132 88 rs536357517 0.1984 -0.603 1.0 N 0.83 0.335 0.677900743141 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
P/L 33776 Fn3-132 88 rs536357517 0.1984 -0.603 1.0 N 0.83 0.335 0.677900743141 gnomAD-4.0.0 3.71775E-06 None None None None N None 7.99595E-05 0 None 0 0 None 0 0 0 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.