Structural position:

  • Domain Type: Fn3
  • Aligned Position: 126
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand G

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
P/H 15749 Fn3-1 93 rs761505199 0.5694 -1.434 1.0 D 0.813 0.403 0.608945918356 gnomAD-2.1.1 7.16E-06 None None None None N None 0 0 None 0 1.03008E-04 None 0 None 0 0 0
P/H 15749 Fn3-1 93 rs761505199 0.5694 -1.434 1.0 D 0.813 0.403 0.608945918356 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94856E-04 None 0 0 0 0 0
P/L 15749 Fn3-1 93 None 0.4137 None 0.995 D 0.765 0.471 0.695812936145 gnomAD-4.0.0 6.8463E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.1605E-05 0
P/S 15749 Fn3-1 93 None 0.2891 None 0.966 D 0.729 0.219 0.367992661779 gnomAD-4.0.0 1.59352E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02939E-05
P/L 15849 Fn3-2 92 None 0.1211 None 0.255 N 0.321 0.124 0.356281029322 gnomAD-4.0.0 1.36954E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80007E-06 0 0
P/R 15849 Fn3-2 92 rs772636177 0.1104 0.203 0.001 N 0.135 0.146 0.235664433957 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
P/R 15849 Fn3-2 92 rs772636177 0.1104 0.203 0.001 N 0.135 0.146 0.235664433957 gnomAD-4.0.0 2.73908E-06 None None None None N None 0 0 None 0 0 None 0 1.73792E-04 9.00035E-07 0 3.31774E-05
P/T 15849 Fn3-2 92 rs146181477 0.0876 -0.493 0.255 N 0.215 0.152 None gnomAD-2.1.1 3.41504E-03 None None None None N None 1.24234E-04 7.6561E-04 None 1.06693E-03 0 None 2.17732E-02 None 4E-05 1.75951E-03 2.95775E-03
P/T 15849 Fn3-2 92 rs146181477 0.0876 -0.493 0.255 N 0.215 0.152 None gnomAD-3.1.2 1.75827E-03 None None None None N None 1.69123E-04 1.70828E-03 0 8.66051E-04 0 None 0 0 1.67904E-03 2.36123E-02 1.43816E-03
P/T 15849 Fn3-2 92 rs146181477 0.0876 -0.493 0.255 N 0.215 0.152 None 1000 genomes 5.99042E-03 None None None None N None 0 1.4E-03 None None 0 2E-03 None None None 2.76E-02 None
P/T 15849 Fn3-2 92 rs146181477 0.0876 -0.493 0.255 N 0.215 0.152 None gnomAD-4.0.0 2.18253E-03 None None None None N None 2.40359E-04 9.51681E-04 None 8.45966E-04 4.47748E-05 None 6.2498E-05 4.1336E-03 1.09078E-03 2.12581E-02 2.67663E-03
P/R 15951 Fn3-3 93 None 0.4131 None 1.0 D 0.879 0.474 0.45063746488 gnomAD-4.0.0 1.37309E-06 None None None None N None 0 0 None 0 0 None 0 0 9.014E-07 0 1.66251E-05
P/S 15951 Fn3-3 93 None 0.2334 None 1.0 N 0.797 0.337 0.225902525712 gnomAD-4.0.0 3.43274E-06 None None None None N None 0 0 None 0 0 None 0 0 3.60568E-06 1.17049E-05 0
P/L 16441 Fn3-6 91 rs570251027 0.2142 None 0.986 N 0.651 0.371 0.570232391912 gnomAD-4.0.0 1.59433E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86241E-06 0 0
P/L 16642 Fn3-8 92 rs2056587744 0.2087 None 0.518 D 0.722 0.326 0.66200615542 gnomAD-4.0.0 1.59546E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86402E-06 0 0
I/N 16843 Fn3-10 93 None 0.3804 None 0.177 N 0.757 0.311 0.684318996799 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
N/H 16945 Fn3-11 94 None 0.1428 None 0.998 N 0.713 0.236 0.198526703765 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
N/S 16945 Fn3-11 94 rs1261279387 0.1168 None 0.952 N 0.467 0.177 0.115124310173 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 16945 Fn3-11 94 rs1261279387 0.1168 None 0.952 N 0.467 0.177 0.115124310173 gnomAD-4.0.0 2.56544E-06 None None None None N None 0 0 None 0 0 None 0 0 4.79175E-06 0 0
P/R 17138 Fn3-12 92 None 0.8115 None 1.0 N 0.921 0.379 0.486993258117 gnomAD-4.0.0 1.5933E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02975E-05
P/S 17138 Fn3-12 92 None 0.5336 None 1.0 N 0.894 0.298 0.377799810692 gnomAD-4.0.0 1.59327E-06 None None None None N None 0 0 None 0 2.78598E-05 None 0 0 0 0 0
P/S 17461 Fn3-14 93 rs2055511936 0.1658 None 0.995 N 0.805 0.283 0.258779203287 gnomAD-4.0.0 1.59742E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86618E-06 0 0
P/H 17561 Fn3-15 92 rs1344423828 0.435 -0.19 0.09 N 0.498 0.291 0.262662153117 gnomAD-2.1.1 4.18E-06 None None None None N None 0 3.01E-05 None 0 0 None 0 None 0 0 0
P/H 17561 Fn3-15 92 rs1344423828 0.435 -0.19 0.09 N 0.498 0.291 0.262662153117 gnomAD-4.0.0 1.61864E-06 None None None None N None 0 2.34896E-05 None 0 0 None 0 0 0 0 0
P/L 17660 Fn3-16 92 None 0.1276 None 0.842 N 0.629 0.351 0.329540904979 gnomAD-4.0.0 2.40064E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 17660 Fn3-16 92 rs957490512 0.1545 -0.498 0.08 N 0.225 0.19 0.151104730317 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
P/S 17660 Fn3-16 92 rs957490512 0.1545 -0.498 0.08 N 0.225 0.19 0.151104730317 gnomAD-4.0.0 1.59297E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86134E-06 0 0
P/R 17853 Fn3-17 90 rs727503609 0.4968 None 1.0 N 0.919 0.551 0.728141607542 gnomAD-4.0.0 3.19817E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8665E-06 0 3.0397E-05
P/S 17853 Fn3-17 90 rs758554548 0.3007 -0.78 1.0 N 0.844 0.358 0.444202592202 gnomAD-2.1.1 4.05E-06 None None None None N None 0 2.93E-05 None 0 0 None 0 None 0 0 0
P/S 17853 Fn3-17 90 rs758554548 0.3007 -0.78 1.0 N 0.844 0.358 0.444202592202 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.57E-05 0 0 0 None 0 0 0 0 0
P/S 17853 Fn3-17 90 rs758554548 0.3007 -0.78 1.0 N 0.844 0.358 0.444202592202 gnomAD-4.0.0 6.58371E-06 None None None None N None 0 6.56944E-05 None 0 0 None 0 0 0 0 0
K/N 18157 Fn3-19 93 rs779495049 0.4128 0.215 0.842 N 0.421 0.101 0.178374595973 gnomAD-2.1.1 2.04E-05 None None None None N None 0 0 None 0 0 None 0 None 0 4.5E-05 0
K/N 18157 Fn3-19 93 rs779495049 0.4128 0.215 0.842 N 0.421 0.101 0.178374595973 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/N 18157 Fn3-19 93 rs779495049 0.4128 0.215 0.842 N 0.421 0.101 0.178374595973 gnomAD-4.0.0 9.3162E-06 None None None None N None 0 0 None 0 0 None 0 4.95376E-04 9.33781E-06 0 1.60514E-05
K/R 18157 Fn3-19 93 rs1177698490 0.0833 0.177 0.842 N 0.423 0.174 0.326616659874 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
K/R 18157 Fn3-19 93 rs1177698490 0.0833 0.177 0.842 N 0.423 0.174 0.326616659874 gnomAD-4.0.0 6.57947E-06 None None None None N None 0 6.55566E-05 None 0 0 None 0 0 0 0 0
P/A 18263 Fn3-20 98 None 0.0705 None 0.104 N 0.393 0.256 0.203808441222 gnomAD-4.0.0 1.60278E-06 None None None None N None 0 0 None 0 0 None 0 0 2.88509E-06 0 0
P/L 18263 Fn3-20 98 None 0.1218 None 0.002 N 0.471 0.142 0.358134431457 gnomAD-4.0.0 6.86437E-07 None None None None N None 0 0 None 0 0 None 0 0 9.0221E-07 0 0
E/D 18366 Fn3-21 95 rs1269570668 0.1382 -0.826 0.997 N 0.651 0.174 0.27855597813 gnomAD-2.1.1 4.04E-06 None None None None N None 0 2.91E-05 None 0 0 None 0 None 0 0 0
E/D 18366 Fn3-21 95 rs1269570668 0.1382 -0.826 0.997 N 0.651 0.174 0.27855597813 gnomAD-4.0.0 7.53128E-06 None None None None N None 0 2.23974E-05 None 0 0 None 0 0 8.09886E-06 0 1.65804E-05
E/K 18366 Fn3-21 95 None 0.2753 None 0.997 N 0.715 0.336 0.420570264827 gnomAD-4.0.0 1.59354E-06 None None None None N None 0 0 None 0 2.78381E-05 None 0 0 0 0 0
R/G 18570 Fn3-22 92 None 0.482 None 0.915 N 0.619 0.182 0.33340067248 gnomAD-4.0.0 1.69102E-06 None None None None N None 0 0 None 0 0 None 0 0 3.00255E-06 0 0
R/K 18570 Fn3-22 92 rs1427580402 0.1661 -0.649 0.817 N 0.433 0.147 None gnomAD-2.1.1 9.12E-06 None None None None N None 0 3.53E-05 None 0 0 None 0 None 0 9.72E-06 0
R/K 18570 Fn3-22 92 rs1427580402 0.1661 -0.649 0.817 N 0.433 0.147 None gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/K 18570 Fn3-22 92 rs1427580402 0.1661 -0.649 0.817 N 0.433 0.147 None gnomAD-4.0.0 9.50676E-06 None None None None N None 0 1.92753E-05 None 0 0 None 0 0 1.50739E-05 0 0
P/S 18875 Fn3-24 92 None 0.1945 None 0.954 N 0.777 0.404 0.33110744837 gnomAD-4.0.0 7.38521E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.79424E-05
P/T 18875 Fn3-24 92 None 0.126 None 0.954 N 0.795 0.425 0.362960570912 gnomAD-4.0.0 7.38521E-07 None None None None N None 0 0 None 0 0 None 0 0 9.40182E-07 0 0
P/L 18980 Fn3-25 97 rs753452704 0.163 -0.08 0.966 N 0.822 0.257 0.433379234345 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14811E-04 0 None 0 0 None 0 None 0 0 0
P/L 18980 Fn3-25 97 rs753452704 0.163 -0.08 0.966 N 0.822 0.257 0.433379234345 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/L 18980 Fn3-25 97 rs753452704 0.163 -0.08 0.966 N 0.822 0.257 0.433379234345 gnomAD-4.0.0 6.57644E-06 None None None None N None 2.41324E-05 0 None 0 0 None 0 0 0 0 0
P/S 18980 Fn3-25 97 None 0.2006 None 0.999 N 0.819 0.278 0.29527378943 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/G 19080 Fn3-26 93 rs2052184132 0.1688 None 0.03 N 0.666 0.154 0.315609569513 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
V/I 19080 Fn3-26 93 rs776003685 0.0649 -0.515 None N 0.122 0.146 0.215869574891 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
V/I 19080 Fn3-26 93 rs776003685 0.0649 -0.515 None N 0.122 0.146 0.215869574891 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
V/I 19080 Fn3-26 93 rs776003685 0.0649 -0.515 None N 0.122 0.146 0.215869574891 gnomAD-4.0.0 3.04501E-06 None None None None N None 3.49406E-05 0 None 0 0 None 0 0 1.20496E-06 0 0
A/E 19275 Fn3-27 93 rs866449199 0.1251 None None N 0.272 0.126 0.154104182512 gnomAD-4.0.0 1.73896E-06 None None None None N None 0 0 None 0 3.01586E-05 None 0 0 0 0 0
A/T 19275 Fn3-27 93 None 0.1047 None 0.026 N 0.389 0.14 0.148003135375 gnomAD-4.0.0 2.83868E-06 None None None None N None 0 0 None 0 0 None 0 0 2.76861E-06 1.25175E-05 0
P/S 19376 Fn3-28 93 None 0.5864 None 0.995 N 0.818 0.362 0.306377322295 gnomAD-4.0.0 3.46185E-06 None None None None N None 0 0 None 0 0 None 0 0 2.71818E-06 0 3.35357E-05
P/T 19376 Fn3-28 93 rs1226665355 0.5639 -1.231 0.997 N 0.789 0.389 0.371344866733 gnomAD-2.1.1 4.23E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.2E-06 0
P/A 19671 Fn3-30 93 rs1426333344 0.091 None 0.999 N 0.855 0.314 0.349647731962 gnomAD-4.0.0 6.84381E-07 None None None None N None 2.98936E-05 0 None 0 0 None 0 0 0 0 0
P/S 19671 Fn3-30 93 rs1426333344 0.2294 -1.144 1.0 N 0.895 0.334 0.373357554552 gnomAD-2.1.1 7.15E-06 None None None None N None 0 0 None 0 1.03167E-04 None 0 None 0 0 0
P/S 19671 Fn3-30 93 rs1426333344 0.2294 -1.144 1.0 N 0.895 0.334 0.373357554552 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94024E-04 None 0 0 0 0 0
P/S 19671 Fn3-30 93 rs1426333344 0.2294 -1.144 1.0 N 0.895 0.334 0.373357554552 gnomAD-4.0.0 1.23974E-06 None None None None N None 0 0 None 0 4.47067E-05 None 0 0 0 0 0
P/R 19968 Fn3-32 92 None 0.587 None 0.974 N 0.669 0.378 0.432266382184 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/T 19968 Fn3-32 92 rs758407490 0.2434 -1.26 0.842 N 0.579 0.3 0.322510055762 gnomAD-2.1.1 8.07E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
P/T 19968 Fn3-32 92 rs758407490 0.2434 -1.26 0.842 N 0.579 0.3 0.322510055762 gnomAD-4.0.0 3.42279E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59878E-06 0 1.6575E-05
P/L 20066 Fn3-33 90 rs750217838 0.3338 -0.537 1.0 N 0.867 0.467 None gnomAD-2.1.1 7.52E-05 None None None None N None 4.14E-05 2.83994E-04 None 0 0 None 3.3E-05 None 0 7.05E-05 0
P/L 20066 Fn3-33 90 rs750217838 0.3338 -0.537 1.0 N 0.867 0.467 None gnomAD-3.1.2 1.11816E-04 None None None None N None 7.24E-05 3.93236E-04 0 0 0 None 0 0 1.02968E-04 0 4.78927E-04
P/L 20066 Fn3-33 90 rs750217838 0.3338 -0.537 1.0 N 0.867 0.467 None gnomAD-4.0.0 4.4029E-05 None None None None N None 4.00952E-05 2.50476E-04 None 0 2.23105E-05 None 0 3.29598E-04 3.56111E-05 2.20609E-05 9.61138E-05
P/S 20066 Fn3-33 90 None 0.3211 None 1.0 N 0.839 0.341 0.51748813702 gnomAD-4.0.0 2.73766E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59863E-06 0 0
P/R 20659 Fn3-37 91 None 0.8737 None 1.0 N 0.867 0.486 0.603037435086 gnomAD-4.0.0 1.59179E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85951E-06 0 0
V/I 20760 Fn3-38 93 None 0.0935 None 0.103 N 0.145 0.138 0.323342291347 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/Q 20954 Fn3-39 91 None 0.3254 None 1.0 N 0.855 0.398 0.477219869099 gnomAD-4.0.0 6.84366E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9957E-07 0 0
P/L 21055 Fn3-40 93 rs779343098 0.167 -0.075 0.995 N 0.75 0.367 0.383089235449 gnomAD-2.1.1 1.08E-05 None None None None N None 0 0 None 0 6.28E-05 None 0 None 0 1.12E-05 0
P/L 21055 Fn3-40 93 rs779343098 0.167 -0.075 0.995 N 0.75 0.367 0.383089235449 gnomAD-4.0.0 7.32158E-06 None None None None N None 0 0 None 0 2.82167E-05 None 0 0 6.38672E-06 0 3.39328E-05
A/P 21162 Fn3-41 99 None 0.1244 None 1.0 N 0.813 0.369 0.299086750705 gnomAD-4.0.0 2.76471E-06 None None None None N None 0 0 None 0 0 None 0 0 3.62749E-06 0 0
K/E 21650 Fn3-44 92 rs2048550217 0.1643 None 0.991 N 0.554 0.239 0.251639045875 gnomAD-4.0.0 1.59198E-06 None None None None I None 5.66508E-05 0 None 0 0 None 0 0 0 0 0
Y/F 21751 Fn3-45 93 rs770569025 0.1057 -0.461 0.001 N 0.145 0.105 0.211220785272 gnomAD-2.1.1 1.72E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.78E-05 0
Y/F 21751 Fn3-45 93 rs770569025 0.1057 -0.461 0.001 N 0.145 0.105 0.211220785272 gnomAD-4.0.0 3.97688E-05 None None None None N None 0 0 None 0 0 None 0 0 5.11289E-05 0 1.69515E-05
Y/H 21751 Fn3-45 93 rs775750677 0.3608 -0.13 0.976 N 0.634 0.185 0.29385284311 gnomAD-2.1.1 1.28E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.82E-05 0
Y/H 21751 Fn3-45 93 rs775750677 0.3608 -0.13 0.976 N 0.634 0.185 0.29385284311 gnomAD-4.0.0 8.2971E-06 None None None None N None 0 0 None 0 0 None 0 0 1.49475E-05 0 0
P/T 21851 Fn3-46 95 None 0.1039 None 0.953 N 0.637 0.249 0.298745278005 gnomAD-4.0.0 6.86624E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.16844E-05 0
P/L 22046 Fn3-47 91 None 0.2846 None 0.666 D 0.723 0.465 0.595302103986 gnomAD-4.0.0 6.96131E-07 None None None None N None 0 0 None 0 0 None 0 0 9.07406E-07 0 0
A/P 22147 Fn3-48 93 rs773148853 0.115 -0.43 0.128 N 0.433 0.278 0.377451072189 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/P 22147 Fn3-48 93 rs773148853 0.115 -0.43 0.128 N 0.433 0.278 0.377451072189 gnomAD-4.0.0 1.59268E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43308E-05 0
A/T 22445 Fn3-50 92 None 0.2275 None 0.851 N 0.545 0.221 0.330331372229 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/V 22445 Fn3-50 92 rs1375354094 0.2805 -0.29 0.958 N 0.591 0.199 0.382761230579 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/V 22445 Fn3-50 92 rs1375354094 0.2805 -0.29 0.958 N 0.591 0.199 0.382761230579 gnomAD-4.0.0 1.59286E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43361E-05 0
P/A 22835 Fn3-53 93 rs750857565 0.0801 -1.143 0.029 N 0.184 0.126 0.185906805712 gnomAD-2.1.1 1.61E-05 None None None None I None 0 1.16185E-04 None 0 0 None 0 None 0 0 0
P/A 22835 Fn3-53 93 rs750857565 0.0801 -1.143 0.029 N 0.184 0.126 0.185906805712 gnomAD-4.0.0 6.37154E-06 None None None None I None 0 9.15122E-05 None 0 0 None 0 0 0 0 0
P/H 22835 Fn3-53 93 rs1187118062 0.346 -1.121 0.998 N 0.589 0.323 0.393775345888 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/H 22835 Fn3-53 93 rs1187118062 0.346 -1.121 0.998 N 0.589 0.323 0.393775345888 gnomAD-4.0.0 1.36904E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79946E-06 0 0
P/L 22835 Fn3-53 93 None 0.2337 None 0.842 N 0.64 0.249 0.459463830659 gnomAD-4.0.0 6.8452E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99729E-07 0 0
T/A 22934 Fn3-54 94 rs749399592 0.0658 -0.755 0.001 N 0.153 0.108 None gnomAD-2.1.1 8.12E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
T/A 22934 Fn3-54 94 rs749399592 0.0658 -0.755 0.001 N 0.153 0.108 None gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/A 22934 Fn3-54 94 rs749399592 0.0658 -0.755 0.001 N 0.153 0.108 None gnomAD-4.0.0 3.59995E-05 None None None None N None 0 0 None 0 0 None 0 0 4.92071E-05 0 0
P/S 23130 Fn3-55 91 None 0.174 None 0.247 N 0.428 0.273 0.231873229951 gnomAD-4.0.0 1.59241E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86061E-06 0 0
S/C 23231 Fn3-56 93 rs776642838 0.0748 -0.432 0.371 N 0.453 0.065 0.269558022972 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/C 23231 Fn3-56 93 rs776642838 0.0748 -0.432 0.371 N 0.453 0.065 0.269558022972 gnomAD-4.0.0 4.10611E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99572E-07 5.80087E-05 0
S/F 23231 Fn3-56 93 rs776642838 0.1297 -1.129 None N 0.387 0.087 0.383590876969 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.68E-05 0
S/F 23231 Fn3-56 93 rs776642838 0.1297 -1.129 None N 0.387 0.087 0.383590876969 gnomAD-4.0.0 1.3687E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79914E-06 0 0
V/A 23333 Fn3-57 94 None 0.2024 None 0.982 N 0.426 0.311 0.661867001231 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
V/F 23333 Fn3-57 94 rs1710003146 0.33 None 0.995 N 0.777 0.299 0.675861982728 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 23621 Fn3-59 90 None 0.1953 None 1.0 N 0.861 0.291 0.21279746466 gnomAD-4.0.0 1.36881E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79922E-06 0 0
P/T 23621 Fn3-59 90 None 0.1676 None 1.0 N 0.857 0.319 0.32714864917 gnomAD-4.0.0 6.84406E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99609E-07 0 0
C/Y 23817 Fn3-60 92 None 0.147 None None N 0.205 0.134 0.47432691512 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/P 24017 Fn3-62 94 rs1459331119 0.1108 -0.192 0.001 N 0.252 0.2 0.12205267543 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 6.5189E-04 None 0 None 0 0 0
A/P 24017 Fn3-62 94 rs1459331119 0.1108 -0.192 0.001 N 0.252 0.2 0.12205267543 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.93798E-04 None 0 0 0 0 0
A/P 24017 Fn3-62 94 rs1459331119 0.1108 -0.192 0.001 N 0.252 0.2 0.12205267543 gnomAD-4.0.0 6.57618E-06 None None None None N None 0 0 None 0 1.93798E-04 None 0 0 0 0 0
T/I 24416 Fn3-65 94 rs768476881 0.0945 0.06 0.013 N 0.283 0.228 0.362758974969 gnomAD-2.1.1 1.79E-05 None None None None N None 2.068E-04 0 None 0 0 None 0 None 0 0 0
T/I 24416 Fn3-65 94 rs768476881 0.0945 0.06 0.013 N 0.283 0.228 0.362758974969 gnomAD-3.1.2 3.29E-05 None None None None N None 1.20715E-04 0 0 0 0 None 0 0 0 0 0
T/I 24416 Fn3-65 94 rs768476881 0.0945 0.06 0.013 N 0.283 0.228 0.362758974969 gnomAD-4.0.0 1.05378E-05 None None None None N None 1.73616E-04 0 None 0 0 None 0 0 3.39104E-06 0 0
S/C 24610 Fn3-66 92 None 0.093 None 0.998 N 0.69 0.362 0.36893422563 gnomAD-4.0.0 1.59631E-06 None None None None N None 0 0 None 0 0 None 1.88352E-05 0 0 0 0
S/F 24610 Fn3-66 92 None 0.4207 None 0.998 N 0.826 0.383 0.335164054921 gnomAD-4.0.0 1.59631E-06 None None None None N None 0 0 None 0 0 None 0 2.42248E-04 0 0 0
P/S 24706 Fn3-67 91 None 0.2522 None 0.546 N 0.583 0.273 0.243398259712 gnomAD-4.0.0 2.05342E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69889E-06 0 0
P/L 24899 Fn3-68 92 rs1708138833 0.1858 None 0.006 N 0.405 0.198 0.481543764896 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 24899 Fn3-68 92 rs1708138833 0.1858 None 0.006 N 0.405 0.198 0.481543764896 gnomAD-4.0.0 2.56338E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78826E-06 0 0
P/T 24899 Fn3-68 92 rs1335200909 0.111 -0.333 None N 0.171 0.114 0.215109475489 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/T 24899 Fn3-68 92 rs1335200909 0.111 -0.333 None N 0.171 0.114 0.215109475489 gnomAD-4.0.0 4.77579E-06 None None None None N None 0 6.86153E-05 None 0 0 None 0 0 0 0 0
C/Y 25000 Fn3-69 93 rs1399533944 0.1981 -1.064 0.162 N 0.689 0.149 0.614824676058 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
C/Y 25000 Fn3-69 93 rs1399533944 0.1981 -1.064 0.162 N 0.689 0.149 0.614824676058 gnomAD-4.0.0 1.59201E-06 None None None None N None 0 2.28676E-05 None 0 0 None 0 0 0 0 0
A/P 25099 Fn3-70 94 None 0.088 None 0.003 N 0.282 0.141 0.149567049428 gnomAD-4.0.0 6.84299E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99572E-07 0 0
A/T 25099 Fn3-70 94 None 0.1297 None 0.518 N 0.48 0.059 0.221734844693 gnomAD-4.0.0 6.84299E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.15939E-05 0
A/V 25099 Fn3-70 94 None 0.1506 None 0.682 N 0.505 0.288 0.344251166708 gnomAD-4.0.0 6.84303E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9957E-07 0 0
P/L 25295 Fn3-71 92 None 0.1626 None 0.693 N 0.637 0.469 0.501874446873 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/T 25295 Fn3-71 92 rs1487092042 0.119 None 0.244 N 0.643 0.163 0.212008924253 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/T 25295 Fn3-71 92 rs1487092042 0.119 None 0.244 N 0.643 0.163 0.212008924253 gnomAD-4.0.0 3.8457E-06 None None None None N None 0 0 None 0 0 None 0 0 7.18174E-06 0 0
Y/D 25396 Fn3-72 93 rs771853872 0.4447 -0.285 0.808 N 0.717 0.308 0.485846224565 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
Y/D 25396 Fn3-72 93 rs771853872 0.4447 -0.285 0.808 N 0.717 0.308 0.485846224565 gnomAD-4.0.0 1.59362E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86231E-06 0 0
P/A 25498 Fn3-73 94 rs377754701 0.0641 -0.486 0.07 N 0.265 0.087 0.223146558224 gnomAD-2.1.1 8.6E-05 None None None None N None 0 0 None 0 0 None 6.92886E-04 None 0 0 0
P/A 25498 Fn3-73 94 rs377754701 0.0641 -0.486 0.07 N 0.265 0.087 0.223146558224 gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 0 None 0 0 0 1.03648E-03 0
P/A 25498 Fn3-73 94 rs377754701 0.0641 -0.486 0.07 N 0.265 0.087 0.223146558224 1000 genomes 5.99042E-04 None None None None N None 0 0 None None 0 0 None None None 3.1E-03 None
P/A 25498 Fn3-73 94 rs377754701 0.0641 -0.486 0.07 N 0.265 0.087 0.223146558224 gnomAD-4.0.0 5.83184E-05 None None None None N None 0 0 None 0 0 None 0 0 0 9.79292E-04 8.01436E-05
P/H 25498 Fn3-73 94 rs374426354 0.1287 None 0.947 N 0.517 0.281 0.432266382184 gnomAD-4.0.0 1.37006E-06 None None None None N None 5.98265E-05 0 None 0 0 None 0 0 0 0 0
P/L 25498 Fn3-73 94 rs374426354 0.1081 -0.133 0.146 N 0.299 0.199 None gnomAD-2.1.1 8.18E-06 None None None None N None 0 2.93E-05 None 0 0 None 0 None 0 9.07E-06 0
P/L 25498 Fn3-73 94 rs374426354 0.1081 -0.133 0.146 N 0.299 0.199 None gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/L 25498 Fn3-73 94 rs374426354 0.1081 -0.133 0.146 N 0.299 0.199 None gnomAD-4.0.0 1.42696E-05 None None None None N None 0 1.67499E-05 None 0 0 None 0 0 1.86598E-05 0 0
P/S 25498 Fn3-73 94 rs377754701 0.0924 -0.648 0.002 N 0.177 0.078 None gnomAD-2.1.1 4.09E-06 None None None None N None 6.59E-05 0 None 0 0 None 0 None 0 0 0
P/S 25498 Fn3-73 94 rs377754701 0.0924 -0.648 0.002 N 0.177 0.078 None gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/S 25498 Fn3-73 94 rs377754701 0.0924 -0.648 0.002 N 0.177 0.078 None gnomAD-4.0.0 1.86136E-06 None None None None N None 4.01016E-05 0 None 0 0 None 0 0 0 0 0
P/T 25498 Fn3-73 94 None 0.0761 None 0.005 N 0.213 0.076 0.230578612272 gnomAD-4.0.0 7.53565E-06 None None None None N None 0 0 None 0 0 None 0 0 9.90122E-06 0 0
P/A 25692 Fn3-74 92 None 0.0704 None 0.603 N 0.411 0.217 0.152612264143 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/A 25788 Fn3-75 91 None 0.175 None 0.949 N 0.557 0.226 0.267755039894 gnomAD-4.0.0 2.40065E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
P/S 25788 Fn3-75 91 rs939575680 0.2626 None 0.832 N 0.341 0.279 0.258283824007 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 1.10132E-03 0 0 None 0 0 0 0 0
P/S 25788 Fn3-75 91 rs939575680 0.2626 None 0.832 N 0.341 0.279 0.258283824007 gnomAD-4.0.0 6.57756E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 0
P/R 25981 Fn3-76 92 rs794729505 0.2329 -0.133 0.314 N 0.711 0.367 0.360565625551 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/R 25981 Fn3-76 92 rs794729505 0.2329 -0.133 0.314 N 0.711 0.367 0.360565625551 gnomAD-4.0.0 1.59174E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
C/G 26082 Fn3-77 93 rs794727452 0.1056 None 0.001 N 0.355 0.256 0.60213386617 gnomAD-4.0.0 2.05288E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69874E-06 0 0
C/S 26082 Fn3-77 93 rs794727452 0.1862 -1.648 0.495 N 0.436 0.23 0.476445137733 gnomAD-2.1.1 7.14E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.56E-05 0
C/S 26082 Fn3-77 93 rs794727452 0.1862 -1.648 0.495 N 0.436 0.23 0.476445137733 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.88E-05 0 0
C/S 26082 Fn3-77 93 rs794727452 0.1862 -1.648 0.495 N 0.436 0.23 0.476445137733 gnomAD-4.0.0 1.23959E-05 None None None None N None 0 0 None 0 0 None 0 0 1.69548E-05 0 0
P/L 26181 Fn3-78 94 rs1467251247 0.1943 None 0.1 N 0.581 0.341 0.376745185316 gnomAD-4.0.0 1.603E-06 None None None None N None 0 0 None 0 0 None 0 0 2.88206E-06 0 0
P/T 26181 Fn3-78 94 None 0.1657 None 0.1 N 0.507 0.141 0.171388866994 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 26377 Fn3-79 92 rs752752131 0.1543 -0.849 0.99 N 0.825 0.326 0.304435445954 gnomAD-2.1.1 1.79E-05 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 1.57E-05 1.40449E-04
P/S 26377 Fn3-79 92 rs752752131 0.1543 -0.849 0.99 N 0.825 0.326 0.304435445954 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/S 26377 Fn3-79 92 rs752752131 0.1543 -0.849 0.99 N 0.825 0.326 0.304435445954 gnomAD-4.0.0 1.11564E-05 None None None None N None 1.33601E-05 0 None 0 0 None 0 0 1.44109E-05 0 0
Y/C 26478 Fn3-80 93 rs1053235966 0.1519 None 1.0 N 0.783 0.383 0.563910400117 gnomAD-4.0.0 1.59203E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85894E-06 0 0
Y/D 26478 Fn3-80 93 rs768735283 0.6338 -3.206 0.993 N 0.869 0.539 0.730013675969 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
Y/D 26478 Fn3-80 93 rs768735283 0.6338 -3.206 0.993 N 0.869 0.539 0.730013675969 gnomAD-4.0.0 1.59209E-06 None None None None N None 5.65803E-05 0 None 0 0 None 0 0 0 0 0
T/I 26580 Fn3-81 94 None 0.0942 None 0.008 N 0.216 0.118 0.17948927462 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/V 26774 Fn3-82 92 rs1272733739 0.2527 -0.207 0.813 N 0.549 0.361 0.372268306217 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
A/V 26774 Fn3-82 92 rs1272733739 0.2527 -0.207 0.813 N 0.549 0.361 0.372268306217 gnomAD-4.0.0 6.36643E-06 None None None None N None 0 2.28634E-05 None 0 8.31901E-05 None 0 0 0 0 0
P/T 26870 Fn3-83 91 rs397517718 0.1979 -0.911 1.0 N 0.879 0.46 0.642435311918 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
P/T 26870 Fn3-83 91 rs397517718 0.1979 -0.911 1.0 N 0.879 0.46 0.642435311918 gnomAD-4.0.0 7.52746E-06 None None None None N None 0 0 None 0 0 None 0 0 8.09629E-06 0 3.31389E-05
A/E 27063 Fn3-84 92 rs1705140581 0.2725 None 0.03 N 0.482 0.141 0.283371740733 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
C/R 27164 Fn3-85 93 None 0.2848 None None N 0.299 0.23 0.474954162714 gnomAD-4.0.0 1.59187E-06 None None None None N None 0 0 None 0 2.78056E-05 None 0 0 0 0 0
P/S 27460 Fn3-87 92 rs1043329468 0.1378 -0.369 0.657 N 0.658 0.254 0.367425347029 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 27460 Fn3-87 92 rs1043329468 0.1378 -0.369 0.657 N 0.658 0.254 0.367425347029 gnomAD-4.0.0 3.09872E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69526E-06 3.29381E-05 0
P/T 27460 Fn3-87 92 rs1043329468 0.1084 None 0.931 N 0.691 0.287 0.441740949975 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/T 27460 Fn3-87 92 rs1043329468 0.1084 None 0.931 N 0.691 0.287 0.441740949975 gnomAD-4.0.0 1.23949E-06 None None None None N None 2.6703E-05 0 None 0 0 None 0 0 0 0 0
F/S 27561 Fn3-88 93 None 0.3946 None 0.013 N 0.45 0.215 0.641573772263 gnomAD-4.0.0 1.59145E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85843E-06 0 0
S/L 27663 Fn3-89 94 None 0.0791 None 0.376 N 0.692 0.206 0.603223074362 gnomAD-4.0.0 1.59145E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85878E-06 0 0
P/A 27857 Fn3-90 92 None 0.068 None 0.002 N 0.229 0.092 0.1749357433 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 27857 Fn3-90 92 None 0.2533 None 0.651 N 0.671 0.317 0.480423546575 gnomAD-4.0.0 6.85636E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00383E-07 0 0
P/S 27953 Fn3-91 91 rs770320215 0.2548 -0.952 1.0 N 0.911 0.461 0.618243236666 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/S 27953 Fn3-91 91 rs770320215 0.2548 -0.952 1.0 N 0.911 0.461 0.618243236666 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 27953 Fn3-91 91 rs770320215 0.2548 -0.952 1.0 N 0.911 0.461 0.618243236666 gnomAD-4.0.0 6.57454E-06 None None None None N None 2.41488E-05 0 None 0 0 None 0 0 0 0 0
A/V 28145 Fn3-92 91 rs765357961 0.1085 0.057 None N 0.14 0.139 0.377097596864 gnomAD-2.1.1 4.07E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.99E-06 0
A/V 28145 Fn3-92 91 rs765357961 0.1085 0.057 None N 0.14 0.139 0.377097596864 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.88E-05 0 0
A/V 28145 Fn3-92 91 rs765357961 0.1085 0.057 None N 0.14 0.139 0.377097596864 gnomAD-4.0.0 2.23817E-05 None None None None N None 0 0 None 0 0 None 0 0 2.97502E-05 0 1.60756E-05
P/L 28246 Fn3-93 93 rs755762249 0.2139 -0.414 0.993 N 0.677 0.33 0.405979908929 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
P/L 28246 Fn3-93 93 rs755762249 0.2139 -0.414 0.993 N 0.677 0.33 0.405979908929 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 28246 Fn3-93 93 rs755762249 0.2139 -0.414 0.993 N 0.677 0.33 0.405979908929 gnomAD-4.0.0 2.47892E-06 None None None None N None 0 0 None 0 0 None 0 0 3.39043E-06 0 0
P/L 28345 Fn3-94 94 rs1453883691 0.2646 -0.222 1.0 N 0.88 0.444 0.772473105538 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.67E-05 0
P/L 28345 Fn3-94 94 rs1453883691 0.2646 -0.222 1.0 N 0.88 0.444 0.772473105538 gnomAD-4.0.0 6.36456E-06 None None None None N None 0 0 None 0 0 None 0 0 1.1432E-05 0 0
A/P 28541 Fn3-95 92 rs1342382839 0.074 -0.2 0.001 N 0.4 0.214 0.272639205421 gnomAD-2.1.1 4.04E-06 None None None None N None 0 2.91E-05 None 0 0 None 0 None 0 0 0
A/P 28541 Fn3-95 92 rs1342382839 0.074 -0.2 0.001 N 0.4 0.214 0.272639205421 gnomAD-4.0.0 1.59348E-06 None None None None N None 0 2.28927E-05 None 0 0 None 0 0 0 0 0
L/F 28642 Fn3-96 93 None 0.116 None 0.999 N 0.793 0.141 0.408307896497 gnomAD-4.0.0 6.842E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99462E-07 0 0
L/S 28642 Fn3-96 93 None 0.2101 None 1.0 N 0.879 0.326 0.778178206519 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 28742 Fn3-97 92 None 0.0868 None 0.001 N 0.439 0.19 0.373173300195 gnomAD-4.0.0 1.59183E-06 None None None None N None 0 2.28655E-05 None 0 0 None 0 0 0 0 0
G/E 28936 Fn3-98 92 rs749842120 0.6828 -0.9 0.999 N 0.839 0.261 0.396044805602 gnomAD-2.1.1 4.26E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.23E-06 0
G/E 28936 Fn3-98 92 rs749842120 0.6828 -0.9 0.999 N 0.839 0.261 0.396044805602 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/E 28936 Fn3-98 92 rs749842120 0.6828 -0.9 0.999 N 0.839 0.261 0.396044805602 gnomAD-4.0.0 6.91362E-06 None None None None N None 0 0 None 0 0 None 0 0 8.55779E-06 0 1.62734E-05
G/R 28936 Fn3-98 92 rs770966722 0.8284 -0.749 0.999 N 0.863 0.315 0.52628473709 gnomAD-2.1.1 4.26E-06 None None None None N None 0 0 None 0 5.76E-05 None 0 None 0 0 0
G/V 28936 Fn3-98 92 None 0.3372 None 0.997 N 0.822 0.303 0.518312163451 gnomAD-4.0.0 2.08492E-06 None None None None N None 0 0 None 0 0 None 0 0 2.72604E-06 0 0
C/R 29228 Fn3-100 92 rs1488529314 0.2043 0.718 0.167 N 0.587 0.214 0.522717468363 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 0 0
C/R 29228 Fn3-100 92 rs1488529314 0.2043 0.718 0.167 N 0.587 0.214 0.522717468363 gnomAD-4.0.0 1.59133E-06 None None None None I None 0 0 None 0 2.77239E-05 None 0 0 0 0 0
C/S 29228 Fn3-100 92 rs1250215219 0.1102 0.466 0.02 N 0.299 0.213 0.460438652622 gnomAD-2.1.1 8.04E-06 None None None None I None 0 5.81E-05 None 0 0 None 0 None 0 0 0
C/S 29228 Fn3-100 92 rs1250215219 0.1102 0.466 0.02 N 0.299 0.213 0.460438652622 gnomAD-4.0.0 1.36844E-06 None None None None I None 0 4.47487E-05 None 0 0 None 0 0 0 0 0
C/Y 29228 Fn3-100 92 None 0.1672 None None N 0.207 0.284 0.490771696789 gnomAD-4.0.0 6.84222E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99437E-07 0 0
P/A 29329 Fn3-101 93 None 0.0785 None 0.005 N 0.276 0.173 0.18274738541 gnomAD-4.0.0 6.84196E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99421E-07 0 0
P/L 29329 Fn3-101 93 rs777177198 0.2586 -0.45 0.799 N 0.671 0.243 0.447410926215 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 9.95E-05 0 None 0 None 0 0 0
P/L 29329 Fn3-101 93 rs777177198 0.2586 -0.45 0.799 N 0.671 0.243 0.447410926215 gnomAD-4.0.0 2.73678E-06 None None None None I None 0 0 None 7.65345E-05 0 None 0 0 1.79884E-06 0 0
P/S 29329 Fn3-101 93 rs376054748 0.1823 None 0.666 N 0.581 0.218 None gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 29329 Fn3-101 93 rs376054748 0.1823 None 0.666 N 0.581 0.218 None gnomAD-4.0.0 6.57134E-06 None None None None I None 2.4122E-05 0 None 0 0 None 0 0 0 0 0
P/T 29329 Fn3-101 93 None 0.1847 None 0.799 N 0.547 0.253 0.288352970974 gnomAD-4.0.0 6.84196E-07 None None None None I None 2.98704E-05 0 None 0 0 None 0 0 0 0 0
P/S 29428 Fn3-102 94 None 0.2483 None 1.0 N 0.863 0.347 0.346768085243 gnomAD-4.0.0 3.1833E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71608E-06 0 0
F/S 29725 Fn3-104 93 rs1284407579 0.4486 -3.342 0.791 N 0.635 0.205 0.69386598177 gnomAD-2.1.1 4.16E-06 None None None None N None 0 0 None 0 0 None 3.43E-05 None 0 0 0
F/S 29725 Fn3-104 93 rs1284407579 0.4486 -3.342 0.791 N 0.635 0.205 0.69386598177 gnomAD-4.0.0 1.6182E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.45964E-05 0
P/H 29827 Fn3-105 94 rs1432117509 0.3875 None 1.0 N 0.885 0.434 0.637480515553 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
P/H 29827 Fn3-105 94 rs1432117509 0.3875 None 1.0 N 0.885 0.434 0.637480515553 gnomAD-4.0.0 1.85987E-06 None None None None N None 2.67044E-05 0 None 0 0 None 0 0 8.47848E-07 0 0
P/R 29827 Fn3-105 94 None 0.3365 None 1.0 N 0.926 0.488 0.59360226722 gnomAD-4.0.0 6.84555E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99745E-07 0 0
P/S 29827 Fn3-105 94 None 0.183 None 1.0 N 0.881 0.273 0.302793454619 gnomAD-4.0.0 6.8452E-07 None None None None N None 0 0 None 0 2.51927E-05 None 0 0 0 0 0
P/T 29827 Fn3-105 94 rs201620815 0.1498 -0.8 1.0 N 0.88 0.248 0.441324992753 gnomAD-2.1.1 2.25969E-04 None None None None N None 0 0 None 0 0 None 1.7401E-03 None 0 2.67E-05 0
P/T 29827 Fn3-105 94 rs201620815 0.1498 -0.8 1.0 N 0.88 0.248 0.441324992753 gnomAD-3.1.2 5.26E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 1.24224E-03 0
P/T 29827 Fn3-105 94 rs201620815 0.1498 -0.8 1.0 N 0.88 0.248 0.441324992753 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
P/T 29827 Fn3-105 94 rs201620815 0.1498 -0.8 1.0 N 0.88 0.248 0.441324992753 gnomAD-4.0.0 9.29844E-05 None None None None N None 0 0 None 0 0 None 0 3.30251E-04 1.52607E-05 1.4183E-03 1.60128E-05
P/A 30024 Fn3-106 92 None 0.0816 None 0.999 N 0.803 0.28 0.28297238246 gnomAD-4.0.0 1.36844E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.15934E-05 1.6564E-05
P/S 30119 Fn3-107 90 rs1183493843 0.2313 -0.674 0.997 N 0.785 0.398 0.462635795511 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 30119 Fn3-107 90 rs1183493843 0.2313 -0.674 0.997 N 0.785 0.398 0.462635795511 gnomAD-4.0.0 1.59139E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
P/T 30119 Fn3-107 90 rs1183493843 0.1904 -0.65 0.999 N 0.768 0.381 0.658592010494 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/T 30119 Fn3-107 90 rs1183493843 0.1904 -0.65 0.999 N 0.768 0.381 0.658592010494 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07297E-04 0
P/T 30119 Fn3-107 90 rs1183493843 0.1904 -0.65 0.999 N 0.768 0.381 0.658592010494 gnomAD-4.0.0 3.84373E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.02048E-05 0
I/T 30315 Fn3-108 92 rs755698637 0.0975 -0.572 None N 0.089 0.112 0.402614778071 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
I/T 30315 Fn3-108 92 rs755698637 0.0975 -0.572 None N 0.089 0.112 0.402614778071 gnomAD-4.0.0 2.73899E-06 None None None None I None 8.96647E-05 0 None 0 2.52143E-05 None 0 0 0 0 0
I/T 30514 Fn3-110 93 rs1699214522 0.1902 None 0.006 N 0.343 0.125 0.489311470972 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/T 30514 Fn3-110 93 rs1699214522 0.1902 None 0.006 N 0.343 0.125 0.489311470972 gnomAD-4.0.0 6.5722E-06 None None None None N None 2.41336E-05 0 None 0 0 None 0 0 0 0 0
I/V 30514 Fn3-110 93 rs1056281241 0.067 -0.791 None N 0.085 0.082 0.298403945805 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
I/V 30514 Fn3-110 93 rs1056281241 0.067 -0.791 None N 0.085 0.082 0.298403945805 gnomAD-4.0.0 1.59292E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8603E-06 0 0
P/T 30710 Fn3-111 92 rs2154148331 0.131 None 0.986 N 0.722 0.282 0.371531589858 gnomAD-4.0.0 3.18571E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72521E-06 0 0
L/F 30812 Fn3-112 94 rs776239659 0.175 -1.217 0.992 N 0.747 0.17 0.445007932271 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
L/F 30812 Fn3-112 94 rs776239659 0.175 -1.217 0.992 N 0.747 0.17 0.445007932271 gnomAD-4.0.0 3.18262E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71582E-06 0 0
T/I 30913 Fn3-113 93 rs778462222 0.0948 0.039 None N 0.148 0.136 0.309530620856 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
T/I 30913 Fn3-113 93 rs778462222 0.0948 0.039 None N 0.148 0.136 0.309530620856 gnomAD-4.0.0 1.59133E-06 None None None None N None 0 2.28666E-05 None 0 0 None 0 0 0 0 0
T/K 30913 Fn3-113 93 rs778462222 0.1489 None 0.011 N 0.313 0.189 0.256283259241 gnomAD-4.0.0 3.18267E-06 None None None None N None 0 0 None 0 5.54847E-05 None 0 0 0 0 0
P/L 31107 Fn3-114 92 None 0.5058 None 1.0 N 0.896 0.411 0.71635906325 gnomAD-4.0.0 1.59109E-06 None None None None N None 0 0 None 0 2.77254E-05 None 0 0 0 0 0
P/Q 31107 Fn3-114 92 None 0.6096 None 1.0 N 0.892 0.395 0.568214726415 gnomAD-4.0.0 1.59109E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85791E-06 0 0
P/S 31107 Fn3-114 92 None 0.2903 None 1.0 N 0.872 0.275 0.259272394797 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/C 31203 Fn3-115 91 rs1208518110 0.1364 -0.335 0.994 N 0.721 0.354 0.44143026662 gnomAD-2.1.1 8.04E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
S/C 31203 Fn3-115 91 rs1208518110 0.1364 -0.335 0.994 N 0.721 0.354 0.44143026662 gnomAD-4.0.0 6.36485E-06 None None None None N None 0 6.86059E-05 None 0 0 None 0 0 0 0 3.02407E-05
S/P 31203 Fn3-115 91 rs1553528649 0.0972 None 0.979 N 0.732 0.302 0.311387274539 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 31399 Fn3-116 92 rs2154146664 0.1094 None 0.666 N 0.716 0.473 0.607483585054 gnomAD-4.0.0 1.6198E-06 None None None None N None 0 0 None 0 2.80978E-05 None 0 0 0 0 0
P/S 31399 Fn3-116 92 None 0.084 None 0.134 N 0.311 0.167 0.162503812791 gnomAD-4.0.0 8.40268E-06 None None None None N None 0 0 None 0 0 None 0 0 9.18797E-06 0 0
P/L 31500 Fn3-117 93 None 0.3065 None 0.949 N 0.812 0.334 0.388010793773 gnomAD-4.0.0 1.36998E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80089E-06 0 0
P/R 31500 Fn3-117 93 rs747518732 0.6671 -0.179 0.987 N 0.901 0.353 0.481616744073 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/R 31500 Fn3-117 93 rs747518732 0.6671 -0.179 0.987 N 0.901 0.353 0.481616744073 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/R 31500 Fn3-117 93 rs747518732 0.6671 -0.179 0.987 N 0.901 0.353 0.481616744073 gnomAD-4.0.0 1.86097E-06 None None None None N None 0 0 None 0 0 None 0 0 2.54542E-06 0 0
P/S 31500 Fn3-117 93 None 0.2474 None 0.949 N 0.833 0.182 0.359557344763 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 31602 Fn3-118 97 rs1697282371 0.1402 None 0.376 N 0.465 0.15 0.294206760003 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 31602 Fn3-118 97 rs1697282371 0.1402 None 0.376 N 0.465 0.15 0.294206760003 gnomAD-4.0.0 2.56835E-06 None None None None N None 3.38581E-05 0 None 0 0 None 0 0 0 0 0
P/A 31798 Fn3-119 91 None 0.0622 None 0.002 N 0.308 0.159 0.128392430309 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/D 32002 Fn3-121 94 None 0.1223 None 0.181 N 0.457 0.11 0.241078983079 gnomAD-4.0.0 2.05345E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69969E-06 0 0
A/P 32196 Fn3-122 92 None 0.1577 None 0.06 N 0.427 0.19 0.223847106136 gnomAD-4.0.0 3.42095E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49724E-06 0 0
A/T 32294 Fn3-123 93 rs751040519 0.1178 -0.753 0.115 N 0.521 0.047 None gnomAD-2.1.1 4.09E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
A/T 32294 Fn3-123 93 rs751040519 0.1178 -0.753 0.115 N 0.521 0.047 None gnomAD-3.1.2 1.99E-05 None None None None N None 7.36E-05 0 0 0 0 None 0 0 0 0 0
A/T 32294 Fn3-123 93 rs751040519 0.1178 -0.753 0.115 N 0.521 0.047 None gnomAD-4.0.0 1.99288E-05 None None None None N None 7.3616E-05 0 None 0 0 None 0 0 0 0 0
A/V 32294 Fn3-123 93 rs1184028880 0.1458 None 0.115 N 0.487 0.165 0.415438038341 gnomAD-3.1.2 1.32E-05 None None None None N None 4.87E-05 0 0 0 0 None 0 0 0 0 0
A/V 32294 Fn3-123 93 rs1184028880 0.1458 None 0.115 N 0.487 0.165 0.415438038341 gnomAD-4.0.0 1.87651E-06 None None None None N None 4.03475E-05 0 None 0 0 None 0 0 0 0 0
V/I 32490 Fn3-124 92 rs935193898 0.0713 -0.289 0.022 N 0.156 0.066 0.194818534648 gnomAD-2.1.1 4.1E-06 None None None None N None 0 2.93E-05 None 0 0 None 0 None 0 0 0
V/I 32490 Fn3-124 92 rs935193898 0.0713 -0.289 0.022 N 0.156 0.066 0.194818534648 gnomAD-4.0.0 4.11265E-06 None None None None N None 0 2.24891E-05 None 0 0 None 0 0 4.50198E-06 0 0
P/H 32591 Fn3-125 93 None 0.2986 None 0.993 N 0.717 0.413 0.563655836063 gnomAD-4.0.0 1.44754E-06 None None None None N None 0 0 None 0 0 None 0 0 1.87663E-06 0 0
P/R 32591 Fn3-125 93 None 0.2733 None 0.868 N 0.731 0.283 0.494299846589 gnomAD-4.0.0 7.23772E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.74429E-05
P/T 32591 Fn3-125 93 None 0.1243 None 0.483 N 0.485 0.151 0.337621943819 gnomAD-4.0.0 7.22291E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.74058E-05
T/I 32692 Fn3-126 93 rs727505311 0.0899 None 0.451 N 0.658 0.161 0.427254322456 gnomAD-4.0.0 6.87862E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.66633E-05
T/R 32692 Fn3-126 93 rs727505311 0.1682 -0.302 0.966 N 0.71 0.219 0.673120225707 gnomAD-2.1.1 3.27E-05 None None None None N None 0 0 None 5.26316E-04 0 None 0 None 0 2.71E-05 0
T/R 32692 Fn3-126 93 rs727505311 0.1682 -0.302 0.966 N 0.71 0.219 0.673120225707 gnomAD-4.0.0 1.92601E-05 None None None None N None 0 0 None 5.46491E-04 0 None 0 0 1.26502E-05 0 0
P/A 32887 Fn3-127 93 rs55653324 0.0708 -1.249 0.029 N 0.231 0.111 0.141422826196 gnomAD-2.1.1 3.22E-05 None None None None N None 0 0 None 0 5.57E-05 None 1.96155E-04 None 0 0 1.65893E-04
P/A 32887 Fn3-127 93 rs55653324 0.0708 -1.249 0.029 N 0.231 0.111 0.141422826196 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07297E-04 0
P/A 32887 Fn3-127 93 rs55653324 0.0708 -1.249 0.029 N 0.231 0.111 0.141422826196 gnomAD-4.0.0 1.92236E-05 None None None None N None 0 0 None 0 2.22955E-05 None 0 0 0 3.29439E-04 0
P/Q 32887 Fn3-127 93 rs774623766 0.3441 -0.979 0.974 N 0.59 0.339 0.280987212366 gnomAD-2.1.1 7.14E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.56E-05 0
P/Q 32887 Fn3-127 93 rs774623766 0.3441 -0.979 0.974 N 0.59 0.339 0.280987212366 gnomAD-4.0.0 6.84775E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00302E-07 0 0
P/R 32887 Fn3-127 93 None 0.3463 None 0.974 N 0.685 0.377 0.313518423057 gnomAD-4.0.0 6.84775E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65755E-05
P/S 32887 Fn3-127 93 None 0.1761 None 0.08 N 0.247 0.166 0.148003135375 gnomAD-4.0.0 1.36944E-06 None None None None N None 0 0 None 0 0 None 0 1.73611E-04 0 1.15955E-05 0
P/T 32887 Fn3-127 93 rs55653324 0.1316 None 0.728 N 0.537 0.185 0.202086224978 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/T 32887 Fn3-127 93 rs55653324 0.1316 None 0.728 N 0.537 0.185 0.202086224978 gnomAD-4.0.0 6.57272E-06 None None None None N None 2.41371E-05 0 None 0 0 None 0 0 0 0 0
P/A 32989 Fn3-128 94 rs779521662 0.065 -0.647 0.702 N 0.523 0.226 0.233150807113 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
P/A 32989 Fn3-128 94 rs779521662 0.065 -0.647 0.702 N 0.523 0.226 0.233150807113 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/A 32989 Fn3-128 94 rs779521662 0.065 -0.647 0.702 N 0.523 0.226 0.233150807113 gnomAD-4.0.0 6.57384E-06 None None None None N None 2.41383E-05 0 None 0 0 None 0 0 0 0 0
P/L 32989 Fn3-128 94 rs757583081 0.1318 -0.214 0.958 N 0.729 0.371 0.675014312329 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.69E-05 0
P/L 32989 Fn3-128 94 rs757583081 0.1318 -0.214 0.958 N 0.729 0.371 0.675014312329 gnomAD-4.0.0 2.95234E-05 None None None None N None 0 0 None 0 0 None 0 0 3.79186E-05 0 1.66362E-05
P/R 32989 Fn3-128 94 None 0.2634 None 0.988 N 0.759 0.385 0.558188439259 gnomAD-4.0.0 6.86591E-07 None None None None N None 0 0 None 0 0 None 0 0 9.02824E-07 0 0
P/S 32989 Fn3-128 94 rs779521662 0.1375 None 0.157 N 0.305 0.237 0.177238962908 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 1.0018E-04 0 None 0 None 0 0 0
P/S 32989 Fn3-128 94 rs779521662 0.1375 None 0.157 N 0.305 0.237 0.177238962908 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 5.77034E-04 0 None 0 0 0 0 0
P/S 32989 Fn3-128 94 rs779521662 0.1375 None 0.157 N 0.305 0.237 0.177238962908 gnomAD-4.0.0 3.86311E-06 None None None None N None 0 0 None 1.23062E-04 0 None 0 0 0 0 0
S/C 33090 Fn3-129 93 None 0.1074 None 0.947 N 0.45 0.266 0.453679287548 gnomAD-4.0.0 6.84784E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9992E-07 0 0
V/A 33383 Fn3-130 94 rs1237202129 0.2303 None 0.189 N 0.52 0.196 0.440705552886 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 9.41E-05 0 0 0 0
V/A 33383 Fn3-130 94 rs1237202129 0.2303 None 0.189 N 0.52 0.196 0.440705552886 gnomAD-4.0.0 2.56461E-06 None None None None N None 0 0 None 0 0 None 1.5704E-05 0 0 0 2.84738E-05
V/I 33383 Fn3-130 94 rs1691876264 0.0997 None 0.001 N 0.218 0.024 0.243398259712 gnomAD-4.0.0 3.18697E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86164E-06 0 3.0281E-05
P/A 33484 Fn3-131 93 None 0.0627 None 0.983 N 0.729 0.228 0.294206760003 gnomAD-4.0.0 1.59167E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43316E-05 0
P/R 33484 Fn3-131 93 rs1235877834 0.2635 -0.204 0.999 N 0.922 0.411 0.443999229985 gnomAD-2.1.1 1.07E-05 None None None None N None 1.24141E-04 0 None 0 0 None 0 None 0 0 0
P/R 33484 Fn3-131 93 rs1235877834 0.2635 -0.204 0.999 N 0.922 0.411 0.443999229985 gnomAD-3.1.2 2.63E-05 None None None None N None 9.66E-05 0 0 0 0 None 0 0 0 0 0
P/R 33484 Fn3-131 93 rs1235877834 0.2635 -0.204 0.999 N 0.922 0.411 0.443999229985 gnomAD-4.0.0 7.68852E-06 None None None None N None 1.01526E-04 0 None 0 0 None 0 0 0 0 0
P/S 33484 Fn3-131 93 rs772916996 0.1166 -0.926 0.911 N 0.397 0.218 0.264081493735 gnomAD-2.1.1 4.02E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
P/S 33484 Fn3-131 93 rs772916996 0.1166 -0.926 0.911 N 0.397 0.218 0.264081493735 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/S 33484 Fn3-131 93 rs772916996 0.1166 -0.926 0.911 N 0.397 0.218 0.264081493735 gnomAD-4.0.0 3.84421E-06 None None None None N None 3.38341E-05 0 None 0 0 None 0 0 2.39325E-06 0 0
P/T 33484 Fn3-131 93 rs772916996 0.095 None 0.995 N 0.832 0.317 0.335910606209 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/T 33484 Fn3-131 93 rs772916996 0.095 None 0.995 N 0.832 0.317 0.335910606209 gnomAD-4.0.0 6.57358E-06 None None None None N None 2.41359E-05 0 None 0 0 None 0 0 0 0 0
P/S 33779 Fn3-132 91 rs1690922403 0.1951 None 0.997 N 0.79 0.295 0.239901079897 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 33779 Fn3-132 91 rs1690922403 0.1951 None 0.997 N 0.79 0.295 0.239901079897 gnomAD-4.0.0 3.84316E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17796E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.