Structural position:
- Domain Type: Fn3
- Aligned Position: 13
- Secondary Structure Element: e
- Secondary Structure Region: β-strand A
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T/A | 15768 |
Fn3-2 |
11 | None | 0.0854 | None | 0.454 | N | 0.277 | 0.15 | 0.202086224978 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/D | 16065 |
Fn3-4 |
11 | rs1490446261 |
0.205 | -0.427 | None | N | 0.257 | 0.048 | 0.0297737177859 | gnomAD-4.0.0 | 6.00162E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| R/G | 16165 |
Fn3-5 |
11 | rs1404754680 |
0.7091 | -0.246 | 1.0 | N | 0.641 | 0.349 | 0.509403866704 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/G | 16165 |
Fn3-5 |
11 | rs1404754680 |
0.7091 | -0.246 | 1.0 | N | 0.641 | 0.349 | 0.509403866704 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 16165 |
Fn3-5 |
11 | rs1404754680 |
0.7091 | -0.246 | 1.0 | N | 0.641 | 0.349 | 0.509403866704 | gnomAD-4.0.0 | 2.56701E-06 | None | None | None | None | N | None | 3.38868E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 16361 |
Fn3-6 |
11 | None | 0.2183 | None | 0.193 | N | 0.403 | 0.254 | 0.258779203287 | gnomAD-4.0.0 | 6.84597E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16001E-05 | 0 |
| T/R | 16361 |
Fn3-6 |
11 | rs2056892277 |
0.2019 | None | 0.627 | N | 0.435 | 0.31 | 0.330589388543 | gnomAD-4.0.0 | 6.84597E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99818E-07 | 0 | 0 |
| S/C | 16460 |
Fn3-7 |
11 | rs397517596 |
0.1542 | -0.127 | 0.99 | D | 0.43 | 0.327 | 0.41337360676 | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.59E-05 | 0 |
| S/C | 16460 |
Fn3-7 |
11 | rs397517596 |
0.1542 | -0.127 | 0.99 | D | 0.43 | 0.327 | 0.41337360676 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/C | 16460 |
Fn3-7 |
11 | rs397517596 |
0.1542 | -0.127 | 0.99 | D | 0.43 | 0.327 | 0.41337360676 | gnomAD-4.0.0 | 2.36007E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.05604E-05 | 0 | 3.2113E-05 |
| I/T | 16661 |
Fn3-9 |
11 | None | 0.2618 | None | 0.961 | N | 0.467 | 0.311 | 0.586144602217 | gnomAD-4.0.0 | 1.3702E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.83083E-05 | 0 | None | 0 | 0 | 0 | 0 | 1.65942E-05 |
| I/V | 16661 |
Fn3-9 |
11 | rs1353241870 |
0.1028 | -0.255 | 0.044 | N | 0.107 | 0.103 | 0.523961927912 | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| I/V | 16661 |
Fn3-9 |
11 | rs1353241870 |
0.1028 | -0.255 | 0.044 | N | 0.107 | 0.103 | 0.523961927912 | gnomAD-4.0.0 | 1.59611E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43521E-05 | 0 |
| V/A | 16761 |
Fn3-10 |
11 | None | 0.1707 | None | 0.826 | N | 0.418 | 0.136 | 0.573410036937 | gnomAD-4.0.0 | 1.59561E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86446E-06 | 0 | 0 |
| V/F | 16761 |
Fn3-10 |
11 | None | 0.2263 | None | 0.996 | N | 0.582 | 0.321 | 0.691532996453 | gnomAD-4.0.0 | 1.59566E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86453E-06 | 0 | 0 |
| V/I | 16761 |
Fn3-10 |
11 | rs769565595 |
0.09 | -0.311 | 0.826 | N | 0.449 | 0.207 | 0.442672919754 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| V/I | 16761 |
Fn3-10 |
11 | rs769565595 |
0.09 | -0.311 | 0.826 | N | 0.449 | 0.207 | 0.442672919754 | gnomAD-4.0.0 | 1.59566E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86453E-06 | 0 | 0 |
| S/N | 17057 |
Fn3-12 |
11 | None | 0.1778 | None | 0.026 | N | 0.28 | 0.185 | 0.149567049428 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| H/D | 17157 |
Fn3-13 |
11 | None | 0.4199 | None | 0.999 | N | 0.552 | 0.406 | 0.33110744837 | gnomAD-4.0.0 | 6.84676E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99913E-07 | 0 | 0 |
| H/R | 17157 |
Fn3-13 |
11 | None | 0.1488 | None | 0.999 | N | 0.483 | 0.272 | 0.319970858106 | gnomAD-4.0.0 | 1.3693E-06 | None | None | None | None | N | None | 5.98767E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/Y | 17157 |
Fn3-13 |
11 | None | 0.1476 | None | 0.4 | N | 0.243 | 0.245 | 0.238096912614 | gnomAD-4.0.0 | 3.42338E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79983E-06 | 1.16031E-05 | 3.31664E-05 |
| E/G | 17379 |
Fn3-14 |
11 | rs1323809346 |
0.3396 | -1.062 | 0.939 | N | 0.604 | 0.467 | 0.404034981753 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.71E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/G | 17379 |
Fn3-14 |
11 | rs1323809346 |
0.3396 | -1.062 | 0.939 | N | 0.604 | 0.467 | 0.404034981753 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 17379 |
Fn3-14 |
11 | rs1323809346 |
0.3396 | -1.062 | 0.939 | N | 0.604 | 0.467 | 0.404034981753 | gnomAD-4.0.0 | 3.8559E-06 | None | None | None | None | N | None | 0 | 5.09096E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 17379 |
Fn3-14 |
11 | rs770795675 |
0.2114 | -0.275 | 0.991 | N | 0.561 | 0.274 | 0.256283259241 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| E/Q | 17379 |
Fn3-14 |
11 | rs770795675 |
0.2114 | -0.275 | 0.991 | N | 0.561 | 0.274 | 0.256283259241 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 17379 |
Fn3-14 |
11 | rs770795675 |
0.2114 | -0.275 | 0.991 | N | 0.561 | 0.274 | 0.256283259241 | gnomAD-4.0.0 | 1.67598E-05 | None | None | None | None | N | None | 2.67451E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.12019E-05 | 0 | 0 |
| E/Q | 17480 |
Fn3-15 |
11 | rs2055452595 |
0.1733 | None | 0.684 | N | 0.409 | 0.103 | 0.21737058555 | gnomAD-4.0.0 | 8.25532E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.08341E-05 | 0 | 0 |
| V/A | 17774 |
Fn3-17 |
11 | rs770511876 |
0.4446 | -0.903 | 0.999 | N | 0.572 | 0.275 | 0.433379234345 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| V/A | 17774 |
Fn3-17 |
11 | rs770511876 |
0.4446 | -0.903 | 0.999 | N | 0.572 | 0.275 | 0.433379234345 | gnomAD-4.0.0 | 1.59361E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86185E-06 | 0 | 0 |
| T/S | 18075 |
Fn3-19 |
11 | rs2054404821 |
0.0982 | None | 0.001 | N | 0.085 | 0.106 | 0.128392430309 | gnomAD-4.0.0 | 2.05463E-06 | None | None | None | None | N | None | 0 | 6.72797E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 18176 |
Fn3-20 |
11 | rs553262724 |
0.1883 | -0.921 | 0.934 | N | 0.659 | 0.101 | 0.536804958393 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14863E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/F | 18176 |
Fn3-20 |
11 | rs553262724 |
0.1883 | -0.921 | 0.934 | N | 0.659 | 0.101 | 0.536804958393 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 18176 |
Fn3-20 |
11 | rs553262724 |
0.1883 | -0.921 | 0.934 | N | 0.659 | 0.101 | 0.536804958393 | gnomAD-4.0.0 | 4.34202E-06 | None | None | None | None | N | None | 9.34829E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/M | 18176 |
Fn3-20 |
11 | rs1211482141 |
0.0999 | -0.566 | 0.934 | N | 0.607 | 0.134 | 0.371344866733 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/M | 18176 |
Fn3-20 |
11 | rs1211482141 |
0.0999 | -0.566 | 0.934 | N | 0.607 | 0.134 | 0.371344866733 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/M | 18176 |
Fn3-20 |
11 | rs1211482141 |
0.0999 | -0.566 | 0.934 | N | 0.607 | 0.134 | 0.371344866733 | gnomAD-4.0.0 | 2.48116E-06 | None | None | None | None | N | None | 5.34759E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/S | 18176 |
Fn3-20 |
11 | None | 0.181 | None | 0.022 | N | 0.304 | 0.187 | 0.47185959272 | gnomAD-4.0.0 | 1.3697E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80019E-06 | 0 | 0 |
| S/I | 18489 |
Fn3-22 |
11 | rs968408582 |
0.2873 | 0.129 | 0.976 | N | 0.503 | 0.34 | 0.599286835281 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| S/I | 18489 |
Fn3-22 |
11 | rs968408582 |
0.2873 | 0.129 | 0.976 | N | 0.503 | 0.34 | 0.599286835281 | gnomAD-4.0.0 | 3.18845E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72787E-06 | 0 | 0 |
| T/A | 18998 |
Fn3-26 |
11 | rs773331027 |
0.1178 | -0.619 | 0.973 | N | 0.58 | 0.203 | 0.268660756437 | gnomAD-2.1.1 | 4.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.09E-06 | 0 |
| T/A | 18998 |
Fn3-26 |
11 | rs773331027 |
0.1178 | -0.619 | 0.973 | N | 0.58 | 0.203 | 0.268660756437 | gnomAD-4.0.0 | 3.22797E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.75152E-06 | 0 | 0 |
| H/R | 19194 |
Fn3-27 |
12 | None | 0.098 | None | 0.024 | N | 0.247 | 0.115 | 0.185906805712 | gnomAD-4.0.0 | 6.86908E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01502E-07 | 0 | 0 |
| K/N | 19294 |
Fn3-28 |
11 | None | 0.3413 | None | 0.007 | N | 0.123 | 0.037 | 0.0551355673512 | gnomAD-4.0.0 | 1.5964E-06 | None | None | None | None | N | None | 0 | 2.294E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 19490 |
Fn3-29 |
12 | rs374118468 |
0.1179 | -0.225 | 0.996 | N | 0.402 | 0.143 | 0.257786959452 | gnomAD-2.1.1 | 8.1E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| D/E | 19490 |
Fn3-29 |
12 | rs374118468 |
0.1179 | -0.225 | 0.996 | N | 0.402 | 0.143 | 0.257786959452 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 4.83E-05 | 6.55E-05 | 0 | 0 | 3.87747E-04 | None | 0 | 0 | 0 | 4.13736E-04 | 4.78469E-04 |
| D/E | 19490 |
Fn3-29 |
12 | rs374118468 |
0.1179 | -0.225 | 0.996 | N | 0.402 | 0.143 | 0.257786959452 | gnomAD-4.0.0 | 4.10718E-06 | None | None | None | None | N | None | 0 | 2.24034E-05 | None | 0 | 0 | None | 0 | 0 | 4.49811E-06 | 0 | 0 |
| T/K | 19589 |
Fn3-30 |
11 | None | 0.1779 | None | 0.001 | N | 0.149 | 0.192 | 0.273938319068 | gnomAD-4.0.0 | 1.36923E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79928E-05 | 0 | 0 |
| T/R | 19589 |
Fn3-30 |
11 | None | 0.1778 | None | 0.473 | N | 0.353 | 0.234 | 0.344483371355 | gnomAD-4.0.0 | 6.84614E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1632E-05 | 0 |
| I/L | 19690 |
Fn3-31 |
11 | rs1305679009 |
0.1261 | -0.244 | 0.012 | N | 0.203 | 0.055 | 0.275215494804 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| I/L | 19690 |
Fn3-31 |
11 | rs1305679009 |
0.1261 | -0.244 | 0.012 | N | 0.203 | 0.055 | 0.275215494804 | gnomAD-4.0.0 | 6.15944E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09645E-06 | 0 | 0 |
| I/T | 19690 |
Fn3-31 |
11 | rs1359437797 |
0.0816 | -0.365 | 0.002 | N | 0.225 | 0.158 | 0.476445137733 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 19690 |
Fn3-31 |
11 | rs1359437797 |
0.0816 | -0.365 | 0.002 | N | 0.225 | 0.158 | 0.476445137733 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 19690 |
Fn3-31 |
11 | rs1359437797 |
0.0816 | -0.365 | 0.002 | N | 0.225 | 0.158 | 0.476445137733 | gnomAD-4.0.0 | 3.71918E-06 | None | None | None | None | N | None | 5.34131E-05 | 0 | None | 0 | 2.23474E-05 | None | 0 | 0 | 0 | 0 | 1.60138E-05 |
| I/V | 19690 |
Fn3-31 |
11 | rs1305679009 |
0.0651 | -0.287 | None | N | 0.085 | 0.113 | 0.238705975628 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| I/V | 19690 |
Fn3-31 |
11 | rs1305679009 |
0.0651 | -0.287 | None | N | 0.085 | 0.113 | 0.238705975628 | gnomAD-4.0.0 | 6.84382E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52615E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/I | 19887 |
Fn3-32 |
11 | None | 0.2854 | None | 1.0 | N | 0.805 | 0.406 | 0.572589462766 | gnomAD-4.0.0 | 1.5964E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41779E-04 | 0 | 0 | 0 |
| S/R | 19887 |
Fn3-32 |
11 | rs748248730 |
0.6076 | -0.18 | 1.0 | N | 0.811 | 0.334 | 0.433713641954 | gnomAD-2.1.1 | 8.2E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.11E-06 | 1.68634E-04 |
| S/R | 19887 |
Fn3-32 |
11 | rs748248730 |
0.6076 | -0.18 | 1.0 | N | 0.811 | 0.334 | 0.433713641954 | gnomAD-4.0.0 | 1.64429E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.16026E-05 | 0 | 0 |
| V/E | 19987 |
Fn3-33 |
11 | rs2050279012 |
0.2946 | None | 0.062 | N | 0.411 | 0.174 | 0.387850303812 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/M | 20182 |
Fn3-34 |
12 | None | 0.096 | None | 1.0 | N | 0.663 | 0.274 | 0.552125808554 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| T/I | 20281 |
Fn3-35 |
11 | None | 0.1651 | None | 0.473 | N | 0.356 | 0.167 | 0.319686207203 | gnomAD-4.0.0 | 1.37074E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80213E-06 | 0 | 0 |
| T/I | 20579 |
Fn3-37 |
11 | None | 0.2865 | None | 0.497 | N | 0.63 | 0.187 | 0.225215365344 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/V | 20678 |
Fn3-38 |
11 | None | 0.266 | None | 0.852 | N | 0.454 | 0.204 | 0.371344866733 | gnomAD-4.0.0 | 1.5918E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85938E-06 | 0 | 0 |
| V/A | 20874 |
Fn3-39 |
11 | None | 0.0652 | None | None | N | 0.04 | 0.117 | 0.266385636622 | gnomAD-4.0.0 | 1.59737E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8594E-06 | 0 | 0 |
| V/F | 20874 |
Fn3-39 |
11 | None | 0.1182 | None | None | N | 0.162 | 0.218 | 0.243972157842 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 20973 |
Fn3-40 |
11 | rs374657513 |
0.2157 | -0.355 | 0.999 | N | 0.597 | 0.26 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/A | 20973 |
Fn3-40 |
11 | rs374657513 |
0.2157 | -0.355 | 0.999 | N | 0.597 | 0.26 | None | gnomAD-4.0.0 | 3.18432E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77901E-05 | None | 0 | 0 | 2.85956E-06 | 0 | 0 |
| T/P | 20973 |
Fn3-40 |
11 | rs374657513 |
0.7638 | -0.226 | 1.0 | D | 0.841 | 0.33 | 0.416707687347 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.65E-05 | 0 | 0 |
| T/P | 20973 |
Fn3-40 |
11 | rs374657513 |
0.7638 | -0.226 | 1.0 | D | 0.841 | 0.33 | 0.416707687347 | gnomAD-4.0.0 | 1.59216E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88317E-05 | 0 | 0 | 0 | 0 |
| T/A | 21376 |
Fn3-43 |
11 | rs368683686 |
0.105 | -0.527 | 0.906 | N | 0.393 | 0.183 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 21376 |
Fn3-43 |
11 | rs368683686 |
0.105 | -0.527 | 0.906 | N | 0.393 | 0.183 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 21376 |
Fn3-43 |
11 | rs368683686 |
0.105 | -0.527 | 0.906 | N | 0.393 | 0.183 | None | gnomAD-4.0.0 | 8.12071E-06 | None | None | None | None | N | None | 1.74801E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.43512E-06 | 0 | 0 |
| T/S | 21376 |
Fn3-43 |
11 | rs1437293840 |
0.1423 | -0.433 | 0.986 | N | 0.4 | 0.201 | 0.224531998449 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/S | 21376 |
Fn3-43 |
11 | rs1437293840 |
0.1423 | -0.433 | 0.986 | N | 0.4 | 0.201 | 0.224531998449 | gnomAD-4.0.0 | 4.10739E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39906E-06 | 0 | 0 |
| I/T | 21767 |
Fn3-46 |
11 | rs762578274 |
0.0798 | -0.461 | None | N | 0.147 | 0.094 | 0.501940320817 | gnomAD-2.1.1 | 2.31E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 1.24626E-04 | 1.7E-05 | 1.50376E-04 |
| I/T | 21767 |
Fn3-46 |
11 | rs762578274 |
0.0798 | -0.461 | None | N | 0.147 | 0.094 | 0.501940320817 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| I/T | 21767 |
Fn3-46 |
11 | rs762578274 |
0.0798 | -0.461 | None | N | 0.147 | 0.094 | 0.501940320817 | gnomAD-4.0.0 | 3.26701E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 7.89989E-05 | 0 | 4.03085E-05 | 0 | 0 |
| R/K | 22461 |
Fn3-51 |
11 | None | 0.0852 | None | 0.001 | N | 0.167 | 0.094 | 0.0297737177859 | gnomAD-4.0.0 | 3.18459E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72053E-06 | 0 | 0 |
| R/W | 22461 |
Fn3-51 |
11 | None | 0.1079 | None | 0.258 | N | 0.301 | 0.057 | 0.104622674875 | gnomAD-4.0.0 | 3.1846E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86028E-06 | 0 | 3.02627E-05 |
| D/H | 22654 |
Fn3-52 |
12 | rs144295295 |
0.216 | -0.515 | 0.931 | N | 0.694 | 0.267 | None | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 3.367E-04 | None | 0 | None | 0 | 0 | 0 |
| D/H | 22654 |
Fn3-52 |
12 | rs144295295 |
0.216 | -0.515 | 0.931 | N | 0.694 | 0.267 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 9.7012E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 22654 |
Fn3-52 |
12 | rs144295295 |
0.216 | -0.515 | 0.931 | N | 0.694 | 0.267 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 2E-03 | 0 | None | None | None | 0 | None |
| D/H | 22654 |
Fn3-52 |
12 | rs144295295 |
0.216 | -0.515 | 0.931 | N | 0.694 | 0.267 | None | gnomAD-4.0.0 | 1.2689E-04 | None | None | None | None | N | None | 0 | 1.69492E-05 | None | 0 | 2.36113E-03 | None | 0 | 0 | 0 | 0 | 2.84414E-05 |
| V/A | 22753 |
Fn3-53 |
11 | None | 0.1038 | None | 0.625 | N | 0.321 | 0.175 | 0.454331543959 | gnomAD-4.0.0 | 6.85055E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0003E-07 | 0 | 0 |
| V/E | 22753 |
Fn3-53 |
11 | None | 0.2292 | None | 0.966 | N | 0.426 | 0.404 | 0.643200830566 | gnomAD-4.0.0 | 6.85055E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0003E-07 | 0 | 0 |
| V/L | 22753 |
Fn3-53 |
11 | None | 0.121 | None | 0.005 | N | 0.115 | 0.065 | 0.280987212366 | gnomAD-4.0.0 | 6.85103E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1664E-05 | 0 |
| V/M | 22753 |
Fn3-53 |
11 | None | 0.0976 | None | 0.267 | N | 0.227 | 0.092 | 0.31411915649 | gnomAD-4.0.0 | 1.37021E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80007E-06 | 0 | 0 |
| I/T | 22851 |
Fn3-54 |
11 | None | 0.2323 | None | 0.892 | N | 0.625 | 0.34 | 0.659639129211 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 22851 |
Fn3-54 |
11 | None | 0.0956 | None | 0.011 | N | 0.184 | 0.083 | 0.406945738958 | gnomAD-4.0.0 | 1.66115E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.13952E-05 |
| S/C | 23050 |
Fn3-55 |
11 | rs1236505151 |
0.1297 | -0.13 | 0.999 | N | 0.685 | 0.455 | 0.516326692288 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 0 | 2.03477E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/C | 23050 |
Fn3-55 |
11 | rs1236505151 |
0.1297 | -0.13 | 0.999 | N | 0.685 | 0.455 | 0.516326692288 | gnomAD-3.1.2 | 9.21E-05 | None | None | None | None | N | None | 0 | 9.18515E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 23050 |
Fn3-55 |
11 | rs1236505151 |
0.1297 | -0.13 | 0.999 | N | 0.685 | 0.455 | 0.516326692288 | gnomAD-4.0.0 | 2.69292E-05 | None | None | None | None | N | None | 0 | 3.56222E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 23050 |
Fn3-55 |
11 | rs1318329197 |
0.6694 | -0.045 | 0.983 | N | 0.751 | 0.41 | 0.351830644314 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/L | 23149 |
Fn3-56 |
11 | rs1559465254 |
0.1073 | None | 0.326 | N | 0.447 | 0.278 | 0.422883881359 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| S/L | 23149 |
Fn3-56 |
11 | rs1559465254 |
0.1073 | None | 0.326 | N | 0.447 | 0.278 | 0.422883881359 | gnomAD-4.0.0 | 1.59269E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77762E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 23250 |
Fn3-57 |
11 | rs771327436 |
0.1139 | 0.09 | 0.032 | N | 0.261 | 0.141 | 0.252162846088 | gnomAD-2.1.1 | 4.97E-06 | None | None | None | None | I | None | 6.9E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 23250 |
Fn3-57 |
11 | rs771327436 |
0.1139 | 0.09 | 0.032 | N | 0.261 | 0.141 | 0.252162846088 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 23445 |
Fn3-58 |
11 | rs1216746795 |
0.0719 | None | 0.625 | N | 0.335 | 0.17 | 0.162503812791 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| T/I | 23445 |
Fn3-58 |
11 | rs750009240 |
0.1459 | 0.065 | 0.966 | D | 0.437 | 0.265 | 0.383921772103 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 1.15935E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 23445 |
Fn3-58 |
11 | rs750009240 |
0.1459 | 0.065 | 0.966 | D | 0.437 | 0.265 | 0.383921772103 | gnomAD-4.0.0 | 6.37119E-06 | None | None | None | None | N | None | 0 | 9.14913E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/K | 23542 |
Fn3-59 |
11 | None | 0.1825 | None | 0.132 | N | 0.313 | 0.19 | 0.483521307902 | gnomAD-4.0.0 | 6.84243E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15947E-05 | 0 |
| M/R | 23542 |
Fn3-59 |
11 | rs727503570 |
0.2058 | None | 0.398 | N | 0.381 | 0.197 | 0.520056377819 | gnomAD-4.0.0 | 6.84243E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99531E-07 | 0 | 0 |
| M/T | 23542 |
Fn3-59 |
11 | rs727503570 |
0.1114 | None | None | N | 0.126 | 0.212 | 0.577929125939 | gnomAD-4.0.0 | 1.36849E-06 | None | None | None | None | N | None | 2.98811E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99531E-07 | 0 | 0 |
| M/V | 23542 |
Fn3-59 |
11 | rs878918075 |
0.0903 | None | None | N | 0.072 | 0.247 | None | gnomAD-4.0.0 | 1.59144E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85891E-06 | 0 | 0 |
| D/G | 23737 |
Fn3-60 |
12 | None | 0.2313 | None | 0.944 | N | 0.596 | 0.3 | 0.26169431596 | gnomAD-4.0.0 | 1.59329E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86094E-06 | 0 | 0 |
| D/N | 23737 |
Fn3-60 |
12 | rs758836824 |
0.1026 | 0.108 | 0.967 | N | 0.53 | 0.242 | 0.344945010812 | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| D/N | 23737 |
Fn3-60 |
12 | rs758836824 |
0.1026 | 0.108 | 0.967 | N | 0.53 | 0.242 | 0.344945010812 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 23737 |
Fn3-60 |
12 | rs758836824 |
0.1026 | 0.108 | 0.967 | N | 0.53 | 0.242 | 0.344945010812 | gnomAD-4.0.0 | 9.30118E-06 | None | None | None | None | N | None | 1.33554E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18706E-05 | 0 | 0 |
| T/S | 23836 |
Fn3-61 |
11 | None | 0.1018 | None | 0.027 | N | 0.353 | 0.084 | 0.137902524267 | gnomAD-4.0.0 | 1.59271E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86067E-06 | 0 | 0 |
| L/V | 23934 |
Fn3-62 |
11 | rs1465413205 |
0.0687 | None | 0.76 | N | 0.435 | 0.092 | 0.250579442822 | gnomAD-4.0.0 | 1.36858E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15955E-05 | 1.65673E-05 |
| T/I | 24133 |
Fn3-63 |
12 | rs977953337 |
0.1881 | None | 0.497 | N | 0.589 | 0.352 | 0.443388199986 | gnomAD-4.0.0 | 1.41993E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.83867E-06 | 0 | 0 |
| M/I | 24626 |
Fn3-67 |
11 | rs1060500561 |
0.1602 | None | None | N | 0.051 | 0.177 | 0.21737058555 | gnomAD-4.0.0 | 2.73769E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 3.47343E-04 | 8.99627E-07 | 0 | 1.65722E-05 |
| T/I | 25314 |
Fn3-72 |
11 | rs1707646875 |
0.2987 | None | 0.984 | D | 0.599 | 0.407 | 0.508517017164 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 25314 |
Fn3-72 |
11 | rs1707646875 |
0.2987 | None | 0.984 | D | 0.599 | 0.407 | 0.508517017164 | gnomAD-4.0.0 | 6.57661E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4708E-05 | 0 | 0 |
| T/S | 25314 |
Fn3-72 |
11 | None | 0.1266 | None | 0.046 | N | 0.167 | 0.077 | 0.203808441222 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/R | 25415 |
Fn3-73 |
11 | rs748670245 |
0.1126 | 0.043 | 0.055 | N | 0.45 | 0.105 | 0.26547132957 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| I/R | 25415 |
Fn3-73 |
11 | rs748670245 |
0.1126 | 0.043 | 0.055 | N | 0.45 | 0.105 | 0.26547132957 | gnomAD-4.0.0 | 8.89644E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.16945E-05 | 0 | 0 |
| I/T | 25415 |
Fn3-73 |
11 | rs748670245 |
0.0495 | -0.954 | None | N | 0.121 | 0.105 | 0.173771789658 | gnomAD-4.0.0 | 2.73737E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.82966E-05 | 0 | None | 0 | 0 | 8.99573E-07 | 1.15955E-05 | 1.65711E-05 |
| I/V | 25415 |
Fn3-73 |
11 | rs1707513771 |
0.0579 | None | None | N | 0.053 | 0.148 | 0.225215365344 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 25611 |
Fn3-74 |
11 | None | 0.0978 | None | 0.001 | N | 0.15 | 0.218 | 0.393775345888 | gnomAD-4.0.0 | 6.85287E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00461E-07 | 0 | 0 |
| D/E | 25901 |
Fn3-76 |
12 | rs765603724 |
0.1272 | 0.044 | 0.767 | N | 0.248 | 0.141 | 0.323886383625 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| D/E | 25901 |
Fn3-76 |
12 | rs765603724 |
0.1272 | 0.044 | 0.767 | N | 0.248 | 0.141 | 0.323886383625 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/E | 25901 |
Fn3-76 |
12 | rs765603724 |
0.1272 | 0.044 | 0.767 | N | 0.248 | 0.141 | 0.323886383625 | gnomAD-4.0.0 | 3.04506E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.61493E-06 | 0 | 0 |
| T/I | 26000 |
Fn3-77 |
11 | rs794729506 |
0.1135 | 0.202 | 0.782 | N | 0.61 | 0.181 | 0.3085936734 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| T/I | 26000 |
Fn3-77 |
11 | rs794729506 |
0.1135 | 0.202 | 0.782 | N | 0.61 | 0.181 | 0.3085936734 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/I | 26000 |
Fn3-77 |
11 | rs794729506 |
0.1135 | 0.202 | 0.782 | N | 0.61 | 0.181 | 0.3085936734 | gnomAD-4.0.0 | 8.67745E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23125E-05 | None | 0 | 1.64636E-04 | 9.3251E-06 | 0 | 1.60149E-05 |
| T/A | 26297 |
Fn3-79 |
12 | None | 0.0851 | None | 0.003 | N | 0.093 | 0.136 | 0.112648838833 | gnomAD-4.0.0 | 1.60862E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.7787E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 26497 |
Fn3-81 |
11 | None | 0.0652 | None | 0.001 | N | 0.221 | 0.036 | 0.37262878642 | gnomAD-4.0.0 | 1.5934E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76735E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 26693 |
Fn3-82 |
11 | None | 0.31 | None | 0.678 | N | 0.593 | 0.283 | 0.284539287134 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 26693 |
Fn3-82 |
11 | rs544750835 |
0.0777 | 0.039 | 0.009 | N | 0.291 | 0.103 | 0.17948927462 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| K/R | 26693 |
Fn3-82 |
11 | rs544750835 |
0.0777 | 0.039 | 0.009 | N | 0.291 | 0.103 | 0.17948927462 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 26693 |
Fn3-82 |
11 | rs544750835 |
0.0777 | 0.039 | 0.009 | N | 0.291 | 0.103 | 0.17948927462 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| K/R | 26693 |
Fn3-82 |
11 | rs544750835 |
0.0777 | 0.039 | 0.009 | N | 0.291 | 0.103 | 0.17948927462 | gnomAD-4.0.0 | 6.5678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4705E-05 | 0 | 0 |
| T/I | 26790 |
Fn3-83 |
11 | rs1023059265 |
0.1259 | None | 0.032 | N | 0.247 | 0.158 | 0.235664433957 | gnomAD-4.0.0 | 1.59167E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85933E-06 | 0 | 0 |
| D/E | 26983 |
Fn3-84 |
12 | rs775115560 |
0.1836 | -0.162 | 0.099 | N | 0.213 | 0.107 | 0.0716867268079 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| D/E | 26983 |
Fn3-84 |
12 | rs775115560 |
0.1836 | -0.162 | 0.099 | N | 0.213 | 0.107 | 0.0716867268079 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/E | 26983 |
Fn3-84 |
12 | rs775115560 |
0.1836 | -0.162 | 0.099 | N | 0.213 | 0.107 | 0.0716867268079 | gnomAD-4.0.0 | 6.57402E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4705E-05 | 0 | 0 |
| D/N | 26983 |
Fn3-84 |
12 | None | 0.1478 | None | 0.983 | N | 0.563 | 0.34 | 0.235664433957 | gnomAD-4.0.0 | 1.59197E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77639E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 27082 |
Fn3-85 |
11 | rs368265185 |
0.1385 | 0.097 | 0.968 | N | 0.605 | 0.326 | None | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| T/I | 27082 |
Fn3-85 |
11 | rs368265185 |
0.1385 | 0.097 | 0.968 | N | 0.605 | 0.326 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 27082 |
Fn3-85 |
11 | rs368265185 |
0.1385 | 0.097 | 0.968 | N | 0.605 | 0.326 | None | gnomAD-4.0.0 | 1.36456E-05 | None | None | None | None | N | None | 2.67458E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69578E-05 | 0 | 0 |
| T/K | 27082 |
Fn3-85 |
11 | rs368265185 |
0.2369 | None | 0.896 | N | 0.577 | 0.265 | 0.389750110748 | gnomAD-4.0.0 | 6.84878E-07 | None | None | None | None | N | None | 2.99976E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 27180 |
Fn3-86 |
11 | rs182126530 |
0.0997 | -0.931 | 0.025 | N | 0.278 | 0.321 | None | gnomAD-2.1.1 | 7.43883E-04 | None | None | None | None | N | None | 5.3341E-03 | 4.24953E-04 | None | 0 | 0 | None | 1.76517E-03 | None | 0 | 5.48E-05 | 4.22535E-04 |
| I/T | 27180 |
Fn3-86 |
11 | rs182126530 |
0.0997 | -0.931 | 0.025 | N | 0.278 | 0.321 | None | gnomAD-3.1.2 | 1.72906E-03 | None | None | None | None | N | None | 5.64835E-03 | 1.11402E-03 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 1.03648E-03 | 1.43403E-03 |
| I/T | 27180 |
Fn3-86 |
11 | rs182126530 |
0.0997 | -0.931 | 0.025 | N | 0.278 | 0.321 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 3.8E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/T | 27180 |
Fn3-86 |
11 | rs182126530 |
0.0997 | -0.931 | 0.025 | N | 0.278 | 0.321 | None | gnomAD-4.0.0 | 4.67309E-04 | None | None | None | None | N | None | 6.34582E-03 | 5.83606E-04 | None | 0 | 0 | None | 0 | 6.59848E-04 | 3.56025E-05 | 1.68003E-03 | 7.04496E-04 |
| S/P | 27479 |
Fn3-88 |
11 | rs1704559289 |
0.7895 | None | 0.007 | N | 0.245 | 0.243 | 0.275215494804 | gnomAD-4.0.0 | 1.59123E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77362E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/M | 27580 |
Fn3-89 |
11 | rs748535477 |
0.0758 | 0.019 | 0.981 | N | 0.631 | 0.317 | 0.570930671769 | gnomAD-2.1.1 | 6.08E-05 | None | None | None | None | N | None | 0 | 5.66E-05 | None | 0 | 1.5456E-04 | None | 2.61438E-04 | None | 0 | 3.14E-05 | 0 |
| T/M | 27580 |
Fn3-89 |
11 | rs748535477 |
0.0758 | 0.019 | 0.981 | N | 0.631 | 0.317 | 0.570930671769 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 2.07383E-04 | 0 |
| T/M | 27580 |
Fn3-89 |
11 | rs748535477 |
0.0758 | 0.019 | 0.981 | N | 0.631 | 0.317 | 0.570930671769 | gnomAD-4.0.0 | 2.72716E-05 | None | None | None | None | N | None | 1.33593E-05 | 3.33622E-05 | None | 0 | 4.46628E-05 | None | 0 | 0 | 1.44104E-05 | 2.08612E-04 | 4.80415E-05 |
| T/S | 27580 |
Fn3-89 |
11 | None | 0.1513 | None | 0.565 | N | 0.505 | 0.105 | 0.141422826196 | gnomAD-4.0.0 | 3.18309E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85855E-06 | 1.43275E-05 | 0 |
| R/K | 27776 |
Fn3-90 |
11 | rs2154160964 |
0.0719 | None | None | N | 0.142 | 0.064 | 0.0954503805726 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/A | 27873 |
Fn3-91 |
11 | rs200775919 |
0.1381 | -0.771 | 0.625 | N | 0.365 | 0.182 | None | gnomAD-2.1.1 | 2.34204E-04 | None | None | None | None | N | None | 0 | 0 | None | 4.39281E-03 | 0 | None | 0 | None | 0 | 1.33381E-04 | 4.26136E-04 |
| V/A | 27873 |
Fn3-91 |
11 | rs200775919 |
0.1381 | -0.771 | 0.625 | N | 0.365 | 0.182 | None | gnomAD-3.1.2 | 1.70945E-04 | None | None | None | None | N | None | 0 | 2.62123E-04 | 0 | 4.89631E-03 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| V/A | 27873 |
Fn3-91 |
11 | rs200775919 |
0.1381 | -0.771 | 0.625 | N | 0.365 | 0.182 | None | gnomAD-4.0.0 | 1.49534E-04 | None | None | None | None | N | None | 0 | 6.70107E-05 | None | 5.52355E-03 | 0 | None | 0 | 3.29381E-04 | 3.56148E-05 | 0 | 4.80846E-04 |
| D/E | 28065 |
Fn3-92 |
11 | rs2154160302 |
0.1781 | None | 0.099 | N | 0.173 | 0.041 | 0.185906805712 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 28065 |
Fn3-92 |
11 | rs2154160302 |
0.1781 | None | 0.099 | N | 0.173 | 0.041 | 0.185906805712 | gnomAD-4.0.0 | 6.56676E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.93349E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 28065 |
Fn3-92 |
11 | rs764469970 |
0.3952 | -0.464 | 0.999 | N | 0.617 | 0.404 | 0.344251166708 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 2.28893E-04 | None | 0 | 0 | 0 |
| D/H | 28065 |
Fn3-92 |
11 | rs764469970 |
0.3952 | -0.464 | 0.999 | N | 0.617 | 0.404 | 0.344251166708 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 0 | 0 | 0 |
| D/H | 28065 |
Fn3-92 |
11 | rs764469970 |
0.3952 | -0.464 | 0.999 | N | 0.617 | 0.404 | 0.344251166708 | gnomAD-4.0.0 | 1.91621E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73551E-04 | 5.39739E-06 | 2.43506E-04 | 0 |
| V/G | 28164 |
Fn3-93 |
11 | rs1703698768 |
0.1364 | None | 0.101 | N | 0.407 | 0.134 | 0.589461000006 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.21507E-04 | 0 |
| V/L | 28164 |
Fn3-93 |
11 | None | 0.1162 | None | 0.001 | N | 0.088 | 0.051 | 0.251639045875 | gnomAD-4.0.0 | 1.60036E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.42836E-04 | 0 | 0 | 0 |
| V/M | 28164 |
Fn3-93 |
11 | None | 0.099 | None | 0.017 | N | 0.231 | 0.058 | 0.302793454619 | gnomAD-4.0.0 | 1.60036E-06 | None | None | None | None | N | None | 0 | 2.3033E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 28262 |
Fn3-94 |
11 | rs1703591532 |
0.1682 | None | 0.014 | N | 0.262 | 0.134 | 0.242825505644 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 28262 |
Fn3-94 |
11 | rs1703591532 |
0.1682 | None | 0.014 | N | 0.262 | 0.134 | 0.242825505644 | gnomAD-4.0.0 | 6.57514E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47024E-05 | 0 | 0 |
| T/A | 28560 |
Fn3-96 |
11 | rs748636733 |
0.1832 | -0.583 | 0.999 | N | 0.553 | 0.485 | 0.41337360676 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/A | 28560 |
Fn3-96 |
11 | rs748636733 |
0.1832 | -0.583 | 0.999 | N | 0.553 | 0.485 | 0.41337360676 | gnomAD-4.0.0 | 1.59183E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85856E-06 | 0 | 0 |
| T/S | 28560 |
Fn3-96 |
11 | rs1703208399 |
0.1758 | None | 0.999 | N | 0.554 | 0.292 | 0.330589388543 | gnomAD-4.0.0 | 1.59182E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85851E-06 | 0 | 0 |
| Q/R | 28855 |
Fn3-98 |
11 | rs1383781795 |
0.0619 | 0.45 | None | N | 0.077 | 0.072 | 0.0986583533028 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Q/R | 28855 |
Fn3-98 |
11 | rs1383781795 |
0.0619 | 0.45 | None | N | 0.077 | 0.072 | 0.0986583533028 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43291E-05 | 0 |
| S/G | 29148 |
Fn3-100 |
12 | None | 0.0914 | None | 0.959 | N | 0.437 | 0.21 | 0.299086750705 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 29345 |
Fn3-102 |
11 | rs878854427 |
0.1069 | None | 0.454 | N | 0.348 | 0.176 | 0.214338557667 | gnomAD-4.0.0 | 1.0949E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4392E-05 | 0 | 0 |
| T/I | 29345 |
Fn3-102 |
11 | rs1701792162 |
0.1782 | None | 0.051 | N | 0.25 | 0.146 | 0.302793454619 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 29345 |
Fn3-102 |
11 | rs1701792162 |
0.1782 | None | 0.051 | N | 0.25 | 0.146 | 0.302793454619 | gnomAD-4.0.0 | 6.5697E-06 | None | None | None | None | N | None | 2.41196E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 29544 |
Fn3-103 |
12 | None | 0.0889 | None | 0.014 | N | 0.194 | 0.065 | 0.151104730317 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 29643 |
Fn3-104 |
11 | None | 0.1436 | None | 0.046 | D | 0.227 | 0.131 | 0.167679373172 | gnomAD-4.0.0 | 1.60337E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77562E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 29643 |
Fn3-104 |
11 | rs1307408186 |
0.4193 | -0.766 | 0.982 | N | 0.597 | 0.35 | 0.473616572423 | gnomAD-2.1.1 | 4.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.43E-05 | None | 0 | 0 | 0 |
| T/K | 29643 |
Fn3-104 |
11 | rs1307408186 |
0.4193 | -0.766 | 0.982 | N | 0.597 | 0.35 | 0.473616572423 | gnomAD-4.0.0 | 4.81084E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.3811E-05 | 0 |
| A/T | 29744 |
Fn3-105 |
11 | rs201592005 |
0.0687 | -0.264 | 0.001 | N | 0.114 | 0.04 | None | gnomAD-2.1.1 | 4.15E-05 | None | None | None | None | N | None | 6.49E-05 | 0 | None | 0 | 5.6E-05 | None | 3.47E-05 | None | 0 | 5.51E-05 | 1.72295E-04 |
| A/T | 29744 |
Fn3-105 |
11 | rs201592005 |
0.0687 | -0.264 | 0.001 | N | 0.114 | 0.04 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 2.07039E-04 | 0 |
| A/T | 29744 |
Fn3-105 |
11 | rs201592005 |
0.0687 | -0.264 | 0.001 | N | 0.114 | 0.04 | None | gnomAD-4.0.0 | 2.86767E-05 | None | None | None | None | N | None | 4.0151E-05 | 1.68458E-05 | None | 0 | 2.23584E-05 | None | 1.57154E-05 | 1.65728E-04 | 2.0444E-05 | 1.22606E-04 | 6.44974E-05 |
| K/E | 29943 |
Fn3-106 |
11 | None | 0.3564 | None | 0.999 | N | 0.614 | 0.406 | 0.335910606209 | gnomAD-4.0.0 | 1.59631E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.7787E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/T | 29943 |
Fn3-106 |
11 | rs532120965 |
0.2193 | -0.381 | 1.0 | N | 0.721 | 0.444 | 0.364730456448 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| K/T | 29943 |
Fn3-106 |
11 | rs532120965 |
0.2193 | -0.381 | 1.0 | N | 0.721 | 0.444 | 0.364730456448 | gnomAD-4.0.0 | 3.19004E-06 | None | None | None | None | N | None | 0 | 2.28875E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43357E-05 | 0 |
| K/E | 30040 |
Fn3-107 |
11 | rs1322454013 |
0.2003 | 0.645 | 0.959 | N | 0.36 | 0.184 | 0.244539031024 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
| K/E | 30040 |
Fn3-107 |
11 | rs1322454013 |
0.2003 | 0.645 | 0.959 | N | 0.36 | 0.184 | 0.244539031024 | gnomAD-4.0.0 | 1.16311E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4391E-05 | 0 | 1.65645E-05 |
| K/N | 30040 |
Fn3-107 |
11 | None | 0.4525 | None | 0.996 | N | 0.389 | 0.175 | 0.17258766438 | gnomAD-4.0.0 | 1.59111E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85794E-06 | 0 | 0 |
| D/E | 30235 |
Fn3-108 |
12 | rs753966975 |
0.152 | -0.206 | 0.006 | N | 0.246 | 0.047 | 0.107399877778 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 30235 |
Fn3-108 |
12 | rs753966975 |
0.152 | -0.206 | 0.006 | N | 0.246 | 0.047 | 0.107399877778 | gnomAD-4.0.0 | 4.1057E-06 | None | None | None | None | N | None | 0 | 2.23714E-05 | None | 0 | 0 | None | 0 | 0 | 4.49754E-06 | 0 | 0 |
| D/N | 30235 |
Fn3-108 |
12 | rs1172858203 |
0.1548 | -0.451 | 0.645 | N | 0.526 | 0.3 | 0.213573922156 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| D/N | 30235 |
Fn3-108 |
12 | rs1172858203 |
0.1548 | -0.451 | 0.645 | N | 0.526 | 0.3 | 0.213573922156 | gnomAD-4.0.0 | 2.05289E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69857E-06 | 0 | 0 |
| Y/C | 30334 |
Fn3-109 |
11 | None | 0.1197 | None | 1.0 | N | 0.693 | 0.323 | 0.482357354261 | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85824E-06 | 0 | 0 |
| Y/D | 30334 |
Fn3-109 |
11 | None | 0.5688 | None | 1.0 | N | 0.709 | 0.506 | 0.676647753298 | gnomAD-4.0.0 | 1.36839E-06 | None | None | None | None | I | None | 5.9755E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 30334 |
Fn3-109 |
11 | None | 0.2058 | None | 1.0 | N | 0.697 | 0.42 | 0.399304321381 | gnomAD-4.0.0 | 6.84195E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99468E-07 | 0 | 0 |
| I/T | 30432 |
Fn3-110 |
11 | None | 0.1203 | None | 0.989 | N | 0.626 | 0.322 | 0.594197360623 | gnomAD-4.0.0 | 2.05359E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.77117E-05 | 0 | 8.99633E-07 | 0 | 0 |
| I/V | 30432 |
Fn3-110 |
11 | rs766841800 |
0.0774 | -0.498 | 0.333 | N | 0.195 | 0.092 | 0.436671004673 | gnomAD-4.0.0 | 1.59297E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43349E-05 | 0 |
| T/A | 30630 |
Fn3-111 |
12 | None | 0.1227 | None | 0.898 | N | 0.509 | 0.312 | 0.266385636622 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 30630 |
Fn3-111 |
12 | rs1305609938 |
0.3899 | -0.037 | 0.997 | N | 0.786 | 0.356 | 0.389126455913 | gnomAD-2.1.1 | 4.24E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.24E-06 | 0 |
| T/I | 30630 |
Fn3-111 |
12 | rs1305609938 |
0.3899 | -0.037 | 0.997 | N | 0.786 | 0.356 | 0.389126455913 | gnomAD-4.0.0 | 7.64067E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.00041E-05 | 0 | 0 |
| S/R | 30729 |
Fn3-112 |
11 | rs778827102 |
0.7384 | 0.099 | 0.901 | N | 0.543 | 0.269 | 0.324161360171 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/R | 30729 |
Fn3-112 |
11 | rs778827102 |
0.7384 | 0.099 | 0.901 | N | 0.543 | 0.269 | 0.324161360171 | gnomAD-4.0.0 | 3.19993E-06 | None | None | None | None | N | None | 5.70386E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03711E-05 |
| K/E | 31026 |
Fn3-114 |
11 | rs759887010 |
0.8448 | 0.572 | 0.939 | N | 0.441 | 0.251 | 0.277730125212 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| K/E | 31026 |
Fn3-114 |
11 | rs759887010 |
0.8448 | 0.572 | 0.939 | N | 0.441 | 0.251 | 0.277730125212 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77269E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 31026 |
Fn3-114 |
11 | rs1698120195 |
0.1053 | None | 0.046 | N | 0.195 | 0.128 | 0.270447802918 | gnomAD-4.0.0 | 2.05255E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69836E-06 | 0 | 0 |
| V/I | 31123 |
Fn3-115 |
11 | rs202096200 |
0.0645 | -0.212 | 0.001 | N | 0.142 | 0.056 | 0.0666544352282 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| V/I | 31123 |
Fn3-115 |
11 | rs202096200 |
0.0645 | -0.212 | 0.001 | N | 0.142 | 0.056 | 0.0666544352282 | gnomAD-4.0.0 | 4.78926E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29606E-06 | 0 | 0 |
| V/L | 31123 |
Fn3-115 |
11 | rs202096200 |
0.1507 | -0.242 | 0.034 | N | 0.287 | 0.05 | None | gnomAD-2.1.1 | 1.0364E-04 | None | None | None | None | N | None | 1.1577E-03 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.40528E-04 |
| V/L | 31123 |
Fn3-115 |
11 | rs202096200 |
0.1507 | -0.242 | 0.034 | N | 0.287 | 0.05 | None | gnomAD-3.1.2 | 3.87892E-04 | None | None | None | None | N | None | 1.39995E-03 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 31123 |
Fn3-115 |
11 | rs202096200 |
0.1507 | -0.242 | 0.034 | N | 0.287 | 0.05 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| V/L | 31123 |
Fn3-115 |
11 | rs202096200 |
0.1507 | -0.242 | 0.034 | N | 0.287 | 0.05 | None | gnomAD-4.0.0 | 7.62164E-05 | None | None | None | None | N | None | 1.47953E-03 | 5.00033E-05 | None | 0 | 0 | None | 0 | 0 | 8.47597E-07 | 0 | 1.28033E-04 |
| S/P | 31319 |
Fn3-116 |
12 | None | 0.8705 | None | 0.999 | N | 0.748 | 0.455 | 0.414930877219 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 31516 |
Fn3-118 |
11 | None | 0.1332 | None | 0.996 | N | 0.491 | 0.288 | 0.324161360171 | gnomAD-4.0.0 | 1.65131E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.98093E-06 | 0 | 0 |
| S/I | 31718 |
Fn3-119 |
11 | rs758006837 |
0.2815 | 0.063 | 0.994 | N | 0.698 | 0.403 | None | gnomAD-2.1.1 | 2.88E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.32E-05 | 0 |
| S/I | 31718 |
Fn3-119 |
11 | rs758006837 |
0.2815 | 0.063 | 0.994 | N | 0.698 | 0.403 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| S/I | 31718 |
Fn3-119 |
11 | rs758006837 |
0.2815 | 0.063 | 0.994 | N | 0.698 | 0.403 | None | gnomAD-4.0.0 | 8.74991E-05 | None | None | None | None | N | None | 4.00588E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.10336E-04 | 0 | 1.28271E-04 |
| S/N | 31718 |
Fn3-119 |
11 | None | 0.1937 | None | 0.4 | N | 0.268 | 0.219 | 0.242244723065 | gnomAD-4.0.0 | 6.85286E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00743E-07 | 0 | 0 |
| S/R | 31718 |
Fn3-119 |
11 | rs781462223 |
0.73 | -0.151 | 0.997 | N | 0.617 | 0.589 | 0.476908202251 | gnomAD-2.1.1 | 5.27E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.27603E-04 | None | 0 | 0 | 0 |
| S/R | 31718 |
Fn3-119 |
11 | rs781462223 |
0.73 | -0.151 | 0.997 | N | 0.617 | 0.589 | 0.476908202251 | gnomAD-4.0.0 | 6.85142E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00586E-07 | 0 | 0 |
| V/A | 31817 |
Fn3-120 |
11 | rs758207460 |
0.0807 | -0.456 | 0.09 | N | 0.332 | 0.126 | 0.356281029322 | gnomAD-2.1.1 | 8.44E-05 | None | None | None | None | I | None | 0 | 4.92868E-04 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 0 | 1.65948E-04 |
| V/A | 31817 |
Fn3-120 |
11 | rs758207460 |
0.0807 | -0.456 | 0.09 | N | 0.332 | 0.126 | 0.356281029322 | gnomAD-3.1.2 | 1.7748E-04 | None | None | None | None | I | None | 0 | 1.76841E-03 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 31817 |
Fn3-120 |
11 | rs758207460 |
0.0807 | -0.456 | 0.09 | N | 0.332 | 0.126 | 0.356281029322 | gnomAD-4.0.0 | 3.78062E-05 | None | None | None | None | I | None | 0 | 8.50198E-04 | None | 0 | 0 | None | 0 | 0 | 3.39091E-06 | 6.58848E-05 | 0 |
| V/L | 31817 |
Fn3-120 |
11 | rs1322909513 |
0.1611 | None | 0.015 | N | 0.173 | 0.036 | 0.282575091529 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/L | 31817 |
Fn3-120 |
11 | rs1322909513 |
0.1611 | None | 0.015 | N | 0.173 | 0.036 | 0.282575091529 | gnomAD-4.0.0 | 6.57047E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46968E-05 | 0 | 0 |
| V/M | 31919 |
Fn3-121 |
11 | rs1696086052 |
0.1103 | None | 0.989 | N | 0.431 | 0.286 | 0.492475246742 | gnomAD-4.0.0 | 1.60365E-06 | None | None | None | None | N | None | 5.68117E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/M | 32115 |
Fn3-122 |
11 | None | 0.3645 | None | 0.999 | N | 0.673 | 0.506 | 0.391775403332 | gnomAD-4.0.0 | 1.62657E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87821E-06 | 0 | 0 |
| D/E | 32410 |
Fn3-124 |
12 | None | 0.128 | None | 0.001 | N | 0.095 | 0.042 | 0.168933306366 | gnomAD-4.0.0 | 6.85687E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01534E-07 | 0 | 0 |
| F/L | 32509 |
Fn3-125 |
11 | None | 0.6718 | None | None | N | 0.129 | 0.244 | 0.225902525712 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/V | 32509 |
Fn3-125 |
11 | rs1233350994 |
0.1574 | -0.632 | 0.09 | N | 0.415 | 0.251 | 0.464183351471 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.65E-05 | None | 0 | None | 0 | 0 | 0 |
| F/V | 32509 |
Fn3-125 |
11 | rs1233350994 |
0.1574 | -0.632 | 0.09 | N | 0.415 | 0.251 | 0.464183351471 | gnomAD-4.0.0 | 9.60257E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.05E-05 | 0 | 0 |
| T/A | 32610 |
Fn3-126 |
11 | None | 0.2373 | None | 0.999 | N | 0.545 | 0.355 | 0.259272394797 | gnomAD-4.0.0 | 1.59197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8599E-06 | 0 | 0 |
| T/I | 32610 |
Fn3-126 |
11 | None | 0.2951 | None | 1.0 | N | 0.799 | 0.424 | 0.52714902651 | gnomAD-4.0.0 | 1.59201E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85982E-06 | 0 | 0 |
| L/F | 32907 |
Fn3-128 |
12 | rs774926230 |
0.2358 | -0.478 | 0.968 | N | 0.521 | 0.221 | 0.499727662827 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| L/F | 32907 |
Fn3-128 |
12 | rs774926230 |
0.2358 | -0.478 | 0.968 | N | 0.521 | 0.221 | 0.499727662827 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/F | 32907 |
Fn3-128 |
12 | rs774926230 |
0.2358 | -0.478 | 0.968 | N | 0.521 | 0.221 | 0.499727662827 | gnomAD-4.0.0 | 4.33797E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.91305E-05 | None | 0 | 0 | 2.54291E-06 | 0 | 0 |
| L/V | 32907 |
Fn3-128 |
12 | rs774926230 |
0.0992 | -0.006 | 0.026 | N | 0.167 | 0.11 | 0.327686398923 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11445E-04 | None | 0 | None | 0 | 0 | 0 |
| L/V | 32907 |
Fn3-128 |
12 | rs774926230 |
0.0992 | -0.006 | 0.026 | N | 0.167 | 0.11 | 0.327686398923 | gnomAD-4.0.0 | 2.73694E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.03905E-05 | None | 0 | 0 | 1.79901E-06 | 0 | 0 |
| L/F | 33008 |
Fn3-129 |
11 | rs771594208 |
0.107 | None | 0.966 | N | 0.427 | 0.191 | 0.552698843619 | gnomAD-4.0.0 | 2.74186E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60292E-06 | 0 | 0 |
| E/D | 33301 |
Fn3-130 |
12 | None | 0.188 | None | 0.02 | N | 0.138 | 0.032 | 0.115124310173 | gnomAD-4.0.0 | 1.80048E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.96875E-05 | 0 | 0 |
| E/G | 33301 |
Fn3-130 |
12 | None | 0.5379 | None | 0.939 | N | 0.565 | 0.417 | 0.42828666871 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| E/K | 33301 |
Fn3-130 |
12 | rs72648278 |
0.612 | 0.348 | 0.989 | N | 0.485 | 0.25 | None | gnomAD-2.1.1 | 3.26605E-04 | None | None | None | None | I | None | 1.2408E-04 | 5.68E-05 | None | 0 | 0 | None | 0 | None | 2.81645E-04 | 5.97672E-04 | 4.24809E-04 |
| E/K | 33301 |
Fn3-130 |
12 | rs72648278 |
0.612 | 0.348 | 0.989 | N | 0.485 | 0.25 | None | gnomAD-3.1.2 | 3.81358E-04 | None | None | None | None | I | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 4.73126E-04 | 0 | 7.0553E-04 | 0 | 4.78011E-04 |
| E/K | 33301 |
Fn3-130 |
12 | rs72648278 |
0.612 | 0.348 | 0.989 | N | 0.485 | 0.25 | None | gnomAD-4.0.0 | 5.39021E-04 | None | None | None | None | I | None | 1.06918E-04 | 3.34079E-05 | None | 0 | 0 | None | 3.75799E-04 | 0 | 6.86352E-04 | 0 | 4.17135E-04 |
| T/A | 33402 |
Fn3-131 |
11 | rs777018654 |
0.11 | -0.255 | 0.001 | N | 0.114 | 0.142 | 0.152612264143 | gnomAD-2.1.1 | 1.17E-05 | None | None | None | None | N | None | 0 | 1.04069E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 33402 |
Fn3-131 |
11 | rs777018654 |
0.11 | -0.255 | 0.001 | N | 0.114 | 0.142 | 0.152612264143 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 33402 |
Fn3-131 |
11 | rs777018654 |
0.11 | -0.255 | 0.001 | N | 0.114 | 0.142 | 0.152612264143 | gnomAD-4.0.0 | 4.4247E-06 | None | None | None | None | N | None | 0 | 7.14864E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 33699 |
Fn3-132 |
11 | rs1691031638 |
0.0691 | None | 0.004 | N | 0.195 | 0.072 | 0.17258766438 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.