Structural position:
- Domain Type: Fn3
- Aligned Position: 132
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S/N | 15754 |
Fn3-1 |
98 | rs775878082 |
0.199 | 0.073 | 0.021 | N | 0.14 | 0.094 | 0.16115917748 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| S/N | 15754 |
Fn3-1 |
98 | rs775878082 |
0.199 | 0.073 | 0.021 | N | 0.14 | 0.094 | 0.16115917748 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 15754 |
Fn3-1 |
98 | rs775878082 |
0.199 | 0.073 | 0.021 | N | 0.14 | 0.094 | 0.16115917748 | gnomAD-4.0.0 | 2.56714E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39721E-06 | 1.34383E-05 | 0 |
| D/G | 15855 |
Fn3-2 |
98 | None | 0.812 | None | 0.982 | N | 0.653 | 0.309 | 0.244539031024 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/Y | 15855 |
Fn3-2 |
98 | None | 0.6555 | None | 1.0 | D | 0.766 | 0.326 | 0.316494231283 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66354E-05 |
| D/E | 15956 |
Fn3-3 |
98 | None | 0.3493 | None | 0.999 | N | 0.448 | 0.158 | 0.269111216191 | gnomAD-4.0.0 | 6.85765E-07 | None | None | None | None | N | None | 0 | 2.25398E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 15956 |
Fn3-3 |
98 | rs372881122 |
0.1827 | 0.715 | 1.0 | D | 0.783 | 0.38 | None | gnomAD-2.1.1 | 2.54E-05 | None | None | None | None | N | None | 2.08995E-04 | 0 | None | 0 | 0 | None | 3.31E-05 | None | 0 | 7.96E-06 | 0 |
| D/N | 15956 |
Fn3-3 |
98 | rs372881122 |
0.1827 | 0.715 | 1.0 | D | 0.783 | 0.38 | None | gnomAD-3.1.2 | 5.93E-05 | None | None | None | None | N | None | 1.69115E-04 | 0 | 0 | 0 | 1.94932E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/N | 15956 |
Fn3-3 |
98 | rs372881122 |
0.1827 | 0.715 | 1.0 | D | 0.783 | 0.38 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/N | 15956 |
Fn3-3 |
98 | rs372881122 |
0.1827 | 0.715 | 1.0 | D | 0.783 | 0.38 | None | gnomAD-4.0.0 | 1.55286E-05 | None | None | None | None | N | None | 1.73722E-04 | 0 | None | 0 | 2.25104E-05 | None | 1.56558E-05 | 0 | 6.79117E-06 | 1.10512E-05 | 1.60545E-05 |
| T/A | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0536 | 0.115 | None | N | 0.03 | 0.159 | None | gnomAD-2.1.1 | 2.64832E-04 | None | None | None | None | N | None | 2.52588E-03 | 1.70116E-04 | None | 0 | 1.54242E-04 | None | 0 | None | 0 | 2.35E-05 | 1.40726E-04 |
| T/A | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0536 | 0.115 | None | N | 0.03 | 0.159 | None | gnomAD-3.1.2 | 6.71866E-04 | None | None | None | None | N | None | 2.27174E-03 | 3.94115E-04 | 0 | 0 | 1.95542E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0536 | 0.115 | None | N | 0.03 | 0.159 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | N | None | 3.8E-03 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/A | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0536 | 0.115 | None | N | 0.03 | 0.159 | None | gnomAD-4.0.0 | 1.32734E-04 | None | None | None | None | N | None | 2.33726E-03 | 2.50392E-04 | None | 0 | 6.70211E-05 | None | 0 | 0 | 8.48243E-06 | 0 | 1.76299E-04 |
| T/N | 16151 |
Fn3-4 |
97 | rs1188604829 |
0.0953 | None | 0.011 | N | 0.178 | 0.126 | 0.339793275041 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 16151 |
Fn3-4 |
97 | rs1188604829 |
0.0953 | None | 0.011 | N | 0.178 | 0.126 | 0.339793275041 | gnomAD-4.0.0 | 6.58285E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47232E-05 | 0 | 0 |
| T/P | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0933 | 0.035 | 0.026 | N | 0.339 | 0.089 | 0.348324211639 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/P | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0933 | 0.035 | 0.026 | N | 0.339 | 0.089 | 0.348324211639 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 9.67E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/P | 16151 |
Fn3-4 |
97 | rs186497293 |
0.0933 | 0.035 | 0.026 | N | 0.339 | 0.089 | 0.348324211639 | gnomAD-4.0.0 | 4.96239E-06 | None | None | None | None | N | None | 6.68878E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54471E-06 | 0 | 0 |
| D/G | 16251 |
Fn3-5 |
97 | None | 0.5132 | None | 1.0 | D | 0.793 | 0.43 | 0.420080204436 | gnomAD-4.0.0 | 7.04304E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.69814E-05 |
| D/N | 16251 |
Fn3-5 |
97 | rs199954570 |
0.191 | 0.512 | 1.0 | D | 0.785 | 0.399 | None | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 1.08319E-04 | 0 | None | 0 | None | 0 | 5.4E-05 | 1.66058E-04 |
| D/N | 16251 |
Fn3-5 |
97 | rs199954570 |
0.191 | 0.512 | 1.0 | D | 0.785 | 0.399 | None | gnomAD-3.1.2 | 5.93E-05 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.1781E-04 | 0 | 0 |
| D/N | 16251 |
Fn3-5 |
97 | rs199954570 |
0.191 | 0.512 | 1.0 | D | 0.785 | 0.399 | None | gnomAD-4.0.0 | 3.0539E-05 | None | None | None | None | N | None | 0 | 3.7743E-05 | None | 2.07915E-04 | 0 | None | 0 | 1.67056E-04 | 3.19744E-05 | 0 | 3.27923E-05 |
| Y/C | 16446 |
Fn3-6 |
96 | rs2056847941 |
0.5701 | None | 0.95 | N | 0.733 | 0.316 | 0.149567049428 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07641E-04 | 0 |
| Y/C | 16446 |
Fn3-6 |
96 | rs2056847941 |
0.5701 | None | 0.95 | N | 0.733 | 0.316 | 0.149567049428 | gnomAD-4.0.0 | 2.03051E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20506E-06 | 4.70013E-05 | 0 |
| Y/H | 16446 |
Fn3-6 |
96 | rs774443816 |
0.4907 | 0.689 | 0.623 | N | 0.573 | 0.258 | 0.31077124679 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | I | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 16446 |
Fn3-6 |
96 | rs774443816 |
0.4907 | 0.689 | 0.623 | N | 0.573 | 0.258 | 0.31077124679 | gnomAD-4.0.0 | 1.36998E-06 | None | None | None | None | I | None | 0 | 2.24346E-05 | None | 0 | 0 | None | 0 | 0 | 8.99951E-07 | 0 | 0 |
| D/E | 16547 |
Fn3-7 |
98 | rs767765903 |
0.8309 | 0.125 | 0.999 | N | 0.464 | 0.147 | 0.311387274539 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.37E-05 | None | 0 | 0 | 0 |
| D/E | 16547 |
Fn3-7 |
98 | rs767765903 |
0.8309 | 0.125 | 0.999 | N | 0.464 | 0.147 | 0.311387274539 | gnomAD-4.0.0 | 1.60075E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.45476E-05 | 0 |
| D/N | 16547 |
Fn3-7 |
98 | None | 0.654 | None | 1.0 | N | 0.789 | 0.316 | 0.33835085245 | gnomAD-4.0.0 | 6.85931E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.17335E-05 | 0 |
| D/Y | 16547 |
Fn3-7 |
98 | None | 0.8738 | None | 1.0 | D | 0.833 | 0.456 | 0.72327570688 | gnomAD-4.0.0 | 2.74373E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60179E-06 | 0 | 0 |
| D/G | 16747 |
Fn3-9 |
97 | rs745559631 |
0.8201 | -0.083 | 1.0 | D | 0.766 | 0.399 | 0.391000631824 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| D/E | 16950 |
Fn3-11 |
99 | rs200700386 |
0.5996 | 0.1 | 0.603 | N | 0.284 | 0.046 | 0.221734844693 | gnomAD-2.1.1 | 6.45E-05 | None | None | None | None | N | None | 7.44663E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 16950 |
Fn3-11 |
99 | rs200700386 |
0.5996 | 0.1 | 0.603 | N | 0.284 | 0.046 | 0.221734844693 | gnomAD-3.1.2 | 1.84244E-04 | None | None | None | None | N | None | 6.75904E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 16950 |
Fn3-11 |
99 | rs200700386 |
0.5996 | 0.1 | 0.603 | N | 0.284 | 0.046 | 0.221734844693 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/E | 16950 |
Fn3-11 |
99 | rs200700386 |
0.5996 | 0.1 | 0.603 | N | 0.284 | 0.046 | 0.221734844693 | gnomAD-4.0.0 | 3.65839E-05 | None | None | None | None | N | None | 7.60426E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.2041E-05 |
| D/N | 16950 |
Fn3-11 |
99 | None | 0.6143 | None | 0.999 | N | 0.757 | 0.329 | 0.3349148499 | gnomAD-4.0.0 | 3.42312E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.79925E-05 | 0 |
| D/N | 17143 |
Fn3-12 |
97 | rs1162344519 |
0.6528 | 0.525 | 1.0 | N | 0.773 | 0.294 | 0.271763555656 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/N | 17143 |
Fn3-12 |
97 | rs1162344519 |
0.6528 | 0.525 | 1.0 | N | 0.773 | 0.294 | 0.271763555656 | gnomAD-4.0.0 | 1.59353E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43328E-05 | 0 |
| D/V | 17143 |
Fn3-12 |
97 | None | 0.88 | None | 1.0 | N | 0.777 | 0.391 | 0.484329738948 | gnomAD-4.0.0 | 1.59357E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86193E-06 | 0 | 0 |
| D/E | 17244 |
Fn3-13 |
98 | None | 0.5301 | None | 0.999 | N | 0.527 | 0.156 | 0.257292322809 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| D/G | 17466 |
Fn3-14 |
98 | rs377156953 |
0.8937 | None | 0.919 | N | 0.608 | 0.235 | 0.235664433957 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 17566 |
Fn3-15 |
97 | None | 0.3002 | None | 0.004 | N | 0.381 | 0.227 | 0.262662153117 | gnomAD-4.0.0 | 1.62105E-06 | None | None | None | None | N | None | 0 | 2.36485E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 17665 |
Fn3-16 |
97 | rs768659420 |
0.1635 | -0.203 | 0.702 | N | 0.601 | 0.097 | 0.316198179892 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| E/D | 17665 |
Fn3-16 |
97 | rs768659420 |
0.1635 | -0.203 | 0.702 | N | 0.601 | 0.097 | 0.316198179892 | gnomAD-4.0.0 | 1.59312E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86151E-06 | 0 | 0 |
| E/K | 17665 |
Fn3-16 |
97 | None | 0.3275 | None | 0.919 | N | 0.677 | 0.243 | 0.328752806141 | gnomAD-4.0.0 | 1.59314E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86156E-06 | 0 | 0 |
| D/V | 18162 |
Fn3-19 |
98 | None | 0.8117 | None | 1.0 | N | 0.709 | 0.531 | 0.641425284928 | gnomAD-4.0.0 | 1.59632E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43843E-05 | 0 |
| D/H | 18268 |
Fn3-20 |
103 | rs776957882 |
0.8021 | 0.601 | 1.0 | N | 0.863 | 0.327 | 0.277730125212 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.36E-05 | None | 0 | 0 | 0 |
| D/H | 18268 |
Fn3-20 |
103 | rs776957882 |
0.8021 | 0.601 | 1.0 | N | 0.863 | 0.327 | 0.277730125212 | gnomAD-4.0.0 | 1.67442E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.52486E-05 | 0 |
| D/N | 18268 |
Fn3-20 |
103 | None | 0.3147 | None | 1.0 | N | 0.757 | 0.278 | 0.206339911435 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/N | 18268 |
Fn3-20 |
103 | None | 0.3147 | None | 1.0 | N | 0.757 | 0.278 | 0.206339911435 | gnomAD-4.0.0 | 2.66966E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.52297E-06 | 1.42017E-05 | 0 |
| D/Y | 18268 |
Fn3-20 |
103 | rs776957882 |
0.6025 | None | 1.0 | N | 0.827 | 0.373 | 0.567643136482 | gnomAD-4.0.0 | 1.67442E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.8335E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 18575 |
Fn3-22 |
97 | rs368524442 |
0.8187 | 0.163 | 1.0 | N | 0.881 | 0.503 | 0.52586976336 | gnomAD-2.1.1 | 4.91E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.25E-05 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 18575 |
Fn3-22 |
97 | rs368524442 |
0.8187 | 0.163 | 1.0 | N | 0.881 | 0.503 | 0.52586976336 | gnomAD-4.0.0 | 1.77243E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.1059E-06 | 0 | 0 |
| D/Y | 18681 |
Fn3-23 |
103 | None | 0.6174 | None | None | N | None | 0.465 | None | gnomAD-4.0.0 | 1.59355E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86288E-06 | 0 | 0 |
| N/K | 18880 |
Fn3-24 |
97 | rs200544272 |
0.8481 | 0.551 | 0.999 | N | 0.765 | 0.252 | 0.197625483188 | gnomAD-2.1.1 | 6.96E-05 | None | None | None | None | N | None | 6.13282E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/K | 18880 |
Fn3-24 |
97 | rs200544272 |
0.8481 | 0.551 | 0.999 | N | 0.765 | 0.252 | 0.197625483188 | gnomAD-3.1.2 | 1.05277E-04 | None | None | None | None | N | None | 3.86529E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/K | 18880 |
Fn3-24 |
97 | rs200544272 |
0.8481 | 0.551 | 0.999 | N | 0.765 | 0.252 | 0.197625483188 | gnomAD-4.0.0 | 1.72725E-05 | None | None | None | None | N | None | 3.23388E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 8.84305E-07 | 1.4334E-05 | 1.73166E-05 |
| N/S | 18880 |
Fn3-24 |
97 | rs1391726501 |
0.1932 | 0.334 | 0.997 | N | 0.629 | 0.262 | 0.251116650651 | gnomAD-2.1.1 | 5.95E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.91E-05 | 1.10256E-04 | 0 |
| N/S | 18880 |
Fn3-24 |
97 | rs1391726501 |
0.1932 | 0.334 | 0.997 | N | 0.629 | 0.262 | 0.251116650651 | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.42E-05 | 0 | 1.32407E-04 | 0 | 0 |
| N/S | 18880 |
Fn3-24 |
97 | rs1391726501 |
0.1932 | 0.334 | 0.997 | N | 0.629 | 0.262 | 0.251116650651 | gnomAD-4.0.0 | 2.22597E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 8.32002E-05 | 0 | 2.43424E-05 | 1.86386E-05 | 0 |
| D/N | 18985 |
Fn3-25 |
102 | rs1244503464 |
0.6254 | 0.42 | 1.0 | N | 0.775 | 0.263 | 0.30212335484 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 18985 |
Fn3-25 |
102 | rs1244503464 |
0.6254 | 0.42 | 1.0 | N | 0.775 | 0.263 | 0.30212335484 | gnomAD-4.0.0 | 2.05416E-06 | None | None | None | None | N | None | 2.99706E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79961E-06 | 0 | 0 |
| D/V | 18985 |
Fn3-25 |
102 | None | 0.906 | None | 1.0 | N | 0.801 | 0.494 | 0.527958119908 | gnomAD-4.0.0 | 1.59483E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86244E-06 | 0 | 0 |
| D/N | 19085 |
Fn3-26 |
98 | None | 0.2813 | None | 1.0 | N | 0.767 | 0.326 | 0.422762650823 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 19280 |
Fn3-27 |
98 | rs566966765 |
0.5124 | 0.762 | 0.058 | N | 0.647 | 0.184 | 0.252681307341 | gnomAD-2.1.1 | 6.25E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.58E-05 | 0 |
| D/E | 19381 |
Fn3-28 |
98 | None | 0.414 | None | 0.982 | N | 0.546 | 0.146 | 0.330331372229 | gnomAD-4.0.0 | 1.20035E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66354E-05 |
| D/N | 19381 |
Fn3-28 |
98 | rs1325584288 |
0.3046 | 0.457 | 0.998 | N | 0.733 | 0.332 | 0.330331372229 | gnomAD-2.1.1 | 4.3E-06 | None | None | None | None | N | None | 0 | 3.2E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 19381 |
Fn3-28 |
98 | rs1325584288 |
0.3046 | 0.457 | 0.998 | N | 0.733 | 0.332 | 0.330331372229 | gnomAD-4.0.0 | 1.64633E-06 | None | None | None | None | N | None | 0 | 2.48398E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 19575 |
Fn3-29 |
97 | rs748522705 |
0.5565 | 0.109 | 0.995 | N | 0.771 | 0.464 | 0.426670027402 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 19575 |
Fn3-29 |
97 | rs748522705 |
0.5565 | 0.109 | 0.995 | N | 0.771 | 0.464 | 0.426670027402 | gnomAD-4.0.0 | 1.5961E-06 | None | None | None | None | N | None | 0 | 2.30213E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 19676 |
Fn3-30 |
98 | None | 0.563 | None | 0.999 | N | 0.561 | 0.121 | 0.254761474806 | gnomAD-4.0.0 | 1.20035E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31253E-06 | 0 | 0 |
| D/Y | 19676 |
Fn3-30 |
98 | rs186215280 |
0.6005 | 0.224 | 1.0 | N | 0.843 | 0.389 | None | gnomAD-2.1.1 | 5.24E-05 | None | None | None | None | I | None | 0 | 3.78215E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 19676 |
Fn3-30 |
98 | rs186215280 |
0.6005 | 0.224 | 1.0 | N | 0.843 | 0.389 | None | gnomAD-3.1.2 | 2.03795E-04 | None | None | None | None | I | None | 0 | 1.96515E-03 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/Y | 19676 |
Fn3-30 |
98 | rs186215280 |
0.6005 | 0.224 | 1.0 | N | 0.843 | 0.389 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/Y | 19676 |
Fn3-30 |
98 | rs186215280 |
0.6005 | 0.224 | 1.0 | N | 0.843 | 0.389 | None | gnomAD-4.0.0 | 6.28081E-05 | None | None | None | None | I | None | 0 | 7.80296E-04 | None | 0 | 0 | None | 0 | 0 | 2.39415E-06 | 0 | 5.69087E-05 |
| D/N | 19973 |
Fn3-32 |
97 | rs148353350 |
0.4832 | 0.342 | 0.06 | N | 0.225 | 0.206 | None | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.1288E-04 | None | 6.59E-05 | None | 0 | 0 | 0 |
| D/N | 19973 |
Fn3-32 |
97 | rs148353350 |
0.4832 | 0.342 | 0.06 | N | 0.225 | 0.206 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 19973 |
Fn3-32 |
97 | rs148353350 |
0.4832 | 0.342 | 0.06 | N | 0.225 | 0.206 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| D/N | 19973 |
Fn3-32 |
97 | rs148353350 |
0.4832 | 0.342 | 0.06 | N | 0.225 | 0.206 | None | gnomAD-4.0.0 | 5.58149E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.48009E-05 | None | 0 | 0 | 0 | 6.60997E-05 | 1.602E-05 |
| E/A | 20071 |
Fn3-33 |
95 | rs773208927 |
0.5007 | 0.065 | 0.997 | N | 0.765 | 0.409 | 0.412715890961 | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.69136E-04 | None | 0 | 0 | 0 |
| E/A | 20071 |
Fn3-33 |
95 | rs773208927 |
0.5007 | 0.065 | 0.997 | N | 0.765 | 0.409 | 0.412715890961 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14938E-04 | 0 |
| E/A | 20071 |
Fn3-33 |
95 | rs773208927 |
0.5007 | 0.065 | 0.997 | N | 0.765 | 0.409 | 0.412715890961 | gnomAD-4.0.0 | 1.48989E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.6688E-04 | 0 |
| E/G | 20071 |
Fn3-33 |
95 | None | 0.405 | None | 0.999 | D | 0.644 | 0.403 | 0.477451190609 | gnomAD-4.0.0 | 6.85515E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.17498E-05 | 0 |
| H/R | 20267 |
Fn3-34 |
97 | rs2050075865 |
0.4634 | None | 0.93 | N | 0.36 | 0.218 | 0.292787519742 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 20267 |
Fn3-34 |
97 | rs2050075865 |
0.4634 | None | 0.93 | N | 0.36 | 0.218 | 0.292787519742 | gnomAD-4.0.0 | 1.31508E-05 | None | None | None | None | N | None | 4.82649E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/Y | 20267 |
Fn3-34 |
97 | None | 0.1321 | None | 0.006 | N | 0.252 | 0.172 | 0.198526703765 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| R/Q | 20367 |
Fn3-35 |
97 | rs141973925 |
0.1632 | 0.198 | 1.0 | N | 0.793 | 0.31 | None | gnomAD-2.1.1 | 3.37647E-03 | None | None | None | None | I | None | 8.27198E-04 | 1.24766E-03 | None | 1.06589E-03 | 0 | None | 4.91256E-04 | None | 1.92308E-03 | 6.12666E-03 | 3.2367E-03 |
| R/Q | 20367 |
Fn3-35 |
97 | rs141973925 |
0.1632 | 0.198 | 1.0 | N | 0.793 | 0.31 | None | gnomAD-3.1.2 | 2.91536E-03 | None | None | None | None | I | None | 6.76296E-04 | 2.22951E-03 | 0 | 1.15207E-03 | 0 | None | 1.70068E-03 | 0 | 5.20849E-03 | 0 | 2.39006E-03 |
| R/Q | 20367 |
Fn3-35 |
97 | rs141973925 |
0.1632 | 0.198 | 1.0 | N | 0.793 | 0.31 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | I | None | 8E-04 | 2.9E-03 | None | None | 0 | 3E-03 | None | None | None | 0 | None |
| R/Q | 20367 |
Fn3-35 |
97 | rs141973925 |
0.1632 | 0.198 | 1.0 | N | 0.793 | 0.31 | None | gnomAD-4.0.0 | 4.50992E-03 | None | None | None | None | I | None | 8.00512E-04 | 1.70153E-03 | None | 8.79448E-04 | 0 | None | 1.84525E-03 | 1.82119E-03 | 5.67181E-03 | 3.29786E-04 | 3.81068E-03 |
| R/W | 20367 |
Fn3-35 |
97 | rs727504479 |
0.3052 | -0.408 | 1.0 | N | 0.857 | 0.322 | None | gnomAD-2.1.1 | 6.08E-05 | None | None | None | None | I | None | 2.89495E-04 | 5.67E-05 | None | 0 | 0 | None | 0 | None | 0 | 6.26E-05 | 0 |
| R/W | 20367 |
Fn3-35 |
97 | rs727504479 |
0.3052 | -0.408 | 1.0 | N | 0.857 | 0.322 | None | gnomAD-3.1.2 | 7.24E-05 | None | None | None | None | I | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.17727E-04 | 0 | 0 |
| R/W | 20367 |
Fn3-35 |
97 | rs727504479 |
0.3052 | -0.408 | 1.0 | N | 0.857 | 0.322 | None | gnomAD-4.0.0 | 4.21621E-05 | None | None | None | None | I | None | 1.33604E-04 | 3.33801E-05 | None | 0 | 2.23264E-05 | None | 0 | 0 | 4.23965E-05 | 2.19829E-05 | 4.80538E-05 |
| D/N | 20469 |
Fn3-36 |
99 | rs752372724 |
0.6121 | 0.465 | 1.0 | N | 0.801 | 0.348 | 0.167679373172 | gnomAD-2.1.1 | 4.71E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.01E-05 | 0 |
| D/N | 20469 |
Fn3-36 |
99 | rs752372724 |
0.6121 | 0.465 | 1.0 | N | 0.801 | 0.348 | 0.167679373172 | gnomAD-4.0.0 | 1.70971E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.04036E-06 | 0 | 0 |
| D/V | 20469 |
Fn3-36 |
99 | rs1244702659 |
0.9382 | 0.349 | 1.0 | N | 0.803 | 0.555 | 0.526995340713 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.5445E-04 | None | 0 | None | 0 | 0 | 0 |
| D/V | 20469 |
Fn3-36 |
99 | rs1244702659 |
0.9382 | 0.349 | 1.0 | N | 0.803 | 0.555 | 0.526995340713 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94401E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 20469 |
Fn3-36 |
99 | rs1244702659 |
0.9382 | 0.349 | 1.0 | N | 0.803 | 0.555 | 0.526995340713 | gnomAD-4.0.0 | 6.57748E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.94401E-04 | None | 0 | 0 | 0 | 0 | 0 |
| N/D | 20664 |
Fn3-37 |
96 | rs879206414 |
0.1627 | None | 0.005 | N | 0.129 | 0.139 | None | gnomAD-4.0.0 | 2.02981E-06 | None | None | None | None | I | None | 3.48663E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/I | 20664 |
Fn3-37 |
96 | rs1214786970 |
0.6616 | 0.32 | 0.996 | N | 0.701 | 0.418 | 0.490074841992 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/I | 20664 |
Fn3-37 |
96 | rs1214786970 |
0.6616 | 0.32 | 0.996 | N | 0.701 | 0.418 | 0.490074841992 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/I | 20664 |
Fn3-37 |
96 | rs1214786970 |
0.6616 | 0.32 | 0.996 | N | 0.701 | 0.418 | 0.490074841992 | gnomAD-4.0.0 | 3.84458E-06 | None | None | None | None | I | None | 0 | 3.39006E-05 | None | 0 | 0 | None | 0 | 0 | 2.39399E-06 | 0 | 0 |
| N/K | 20664 |
Fn3-37 |
96 | rs376455983 |
0.8556 | 0.53 | 0.919 | N | 0.52 | 0.183 | 0.173771789658 | gnomAD-2.1.1 | 2.86E-05 | None | None | None | None | I | None | 4.13E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.48E-05 | 0 |
| N/K | 20664 |
Fn3-37 |
96 | rs376455983 |
0.8556 | 0.53 | 0.919 | N | 0.52 | 0.183 | 0.173771789658 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.02968E-04 | 0 | 0 |
| N/K | 20664 |
Fn3-37 |
96 | rs376455983 |
0.8556 | 0.53 | 0.919 | N | 0.52 | 0.183 | 0.173771789658 | gnomAD-4.0.0 | 2.7372E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69874E-06 | 1.15947E-05 | 0 |
| D/A | 20765 |
Fn3-38 |
98 | None | 0.3718 | None | 0.799 | N | 0.529 | 0.257 | 0.365703291355 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/E | 21060 |
Fn3-40 |
98 | rs778030754 |
0.6755 | 0.085 | 0.999 | N | 0.529 | 0.145 | 0.240491677333 | gnomAD-2.1.1 | 5.57E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.15E-05 | 0 |
| D/G | 21060 |
Fn3-40 |
98 | None | 0.8693 | None | 1.0 | N | 0.825 | 0.342 | 0.346544149963 | gnomAD-4.0.0 | 7.2868E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.3289E-07 | 0 | 0 |
| D/H | 21060 |
Fn3-40 |
98 | None | 0.8903 | None | 1.0 | N | 0.894 | 0.379 | 0.391156786388 | gnomAD-4.0.0 | 1.85125E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.21982E-06 | 0 | 0 |
| D/H | 21362 |
Fn3-42 |
97 | None | 0.7378 | None | 1.0 | N | 0.801 | 0.322 | 0.229924730088 | gnomAD-4.0.0 | 1.59245E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88239E-05 | 0 | 0 | 0 | 0 |
| D/V | 21362 |
Fn3-42 |
97 | rs752967519 |
0.7729 | 0.459 | 0.983 | N | 0.599 | 0.274 | 0.502752565406 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65893E-04 |
| D/Y | 21362 |
Fn3-42 |
97 | rs756650236 |
0.6347 | 0.142 | 1.0 | N | 0.79 | 0.339 | 0.577502390439 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65837E-04 |
| E/K | 21463 |
Fn3-43 |
98 | rs1214364121 |
0.8412 | 0.673 | 0.856 | N | 0.653 | 0.258 | 0.311079019809 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| Q/R | 21654 |
Fn3-44 |
96 | rs555785232 |
0.075 | 0.342 | None | N | 0.085 | 0.083 | 0.12205267543 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Q/R | 21654 |
Fn3-44 |
96 | rs555785232 |
0.075 | 0.342 | None | N | 0.085 | 0.083 | 0.12205267543 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 21654 |
Fn3-44 |
96 | rs555785232 |
0.075 | 0.342 | None | N | 0.085 | 0.083 | 0.12205267543 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| Q/R | 21654 |
Fn3-44 |
96 | rs555785232 |
0.075 | 0.342 | None | N | 0.085 | 0.083 | 0.12205267543 | gnomAD-4.0.0 | 2.02989E-06 | None | None | None | None | I | None | 1.7441E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20498E-06 | 0 | 0 |
| M/I | 21756 |
Fn3-45 |
98 | None | 0.454 | None | 0.006 | N | 0.275 | 0.042 | 0.383760037723 | gnomAD-4.0.0 | 7.13598E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.23825E-07 | 0 | 0 |
| A/T | 21856 |
Fn3-46 |
100 | rs752176305 |
0.1468 | -0.359 | 0.988 | N | 0.613 | 0.172 | 0.396494342077 | gnomAD-2.1.1 | 6.66E-05 | None | None | None | None | I | None | 0 | 3.01E-05 | None | 0 | 8.00641E-04 | None | 0 | None | 0 | 9.16E-06 | 0 |
| A/T | 21856 |
Fn3-46 |
100 | rs752176305 |
0.1468 | -0.359 | 0.988 | N | 0.613 | 0.172 | 0.396494342077 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 2.41E-05 | 6.56E-05 | 0 | 0 | 3.89105E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 21856 |
Fn3-46 |
100 | rs752176305 |
0.1468 | -0.359 | 0.988 | N | 0.613 | 0.172 | 0.396494342077 | gnomAD-4.0.0 | 2.12921E-05 | None | None | None | None | I | None | 1.34073E-05 | 3.40437E-05 | None | 0 | 3.1607E-04 | None | 0 | 0 | 1.11175E-05 | 1.12562E-05 | 4.85909E-05 |
| A/V | 21856 |
Fn3-46 |
100 | rs1303979451 |
0.2558 | -0.05 | 0.935 | N | 0.644 | 0.183 | 0.437741185291 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.45E-05 | None | 0 | 0 | 0 |
| A/V | 21856 |
Fn3-46 |
100 | rs1303979451 |
0.2558 | -0.05 | 0.935 | N | 0.644 | 0.183 | 0.437741185291 | gnomAD-4.0.0 | 2.76665E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.72251E-06 | 1.187E-05 | 0 |
| N/T | 22051 |
Fn3-47 |
96 | None | 0.6209 | None | 0.007 | N | 0.403 | 0.237 | 0.227934060464 | gnomAD-4.0.0 | 1.66811E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.95074E-06 | 0 | 0 |
| D/E | 22152 |
Fn3-48 |
98 | None | 0.7199 | None | 0.999 | N | 0.505 | 0.189 | 0.254244900254 | gnomAD-4.0.0 | 1.59298E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43345E-05 | 0 |
| D/N | 22254 |
Fn3-49 |
99 | rs756359190 |
0.6012 | 0.358 | 0.974 | N | 0.765 | 0.441 | None | gnomAD-2.1.1 | 4.21E-06 | None | None | None | None | N | None | 6.5E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 22254 |
Fn3-49 |
99 | rs756359190 |
0.6012 | 0.358 | 0.974 | N | 0.765 | 0.441 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 22254 |
Fn3-49 |
99 | rs756359190 |
0.6012 | 0.358 | 0.974 | N | 0.765 | 0.441 | None | gnomAD-4.0.0 | 3.93266E-06 | None | None | None | None | N | None | 1.70097E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.45704E-06 | 1.39063E-05 | 0 |
| Q/K | 22450 |
Fn3-50 |
97 | None | 0.1889 | None | 0.004 | N | 0.227 | 0.037 | 0.0954503805726 | gnomAD-4.0.0 | 6.84565E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99721E-07 | 0 | 0 |
| Q/P | 22450 |
Fn3-50 |
97 | None | 0.7266 | None | 0.013 | N | 0.373 | None | 0.220303561663 | gnomAD-4.0.0 | 1.59425E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77654E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 22543 |
Fn3-51 |
93 | rs1283302985 |
0.2593 | 0.333 | 1.0 | N | 0.808 | 0.397 | 0.39843156188 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 22543 |
Fn3-51 |
93 | rs1283302985 |
0.2593 | 0.333 | 1.0 | N | 0.808 | 0.397 | 0.39843156188 | gnomAD-4.0.0 | 6.5767E-06 | None | None | None | None | N | None | 2.41324E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 22739 |
Fn3-52 |
97 | rs1170829810 |
0.8791 | -0.118 | 0.938 | N | 0.678 | 0.282 | 0.247872288689 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.34E-05 | None | 0 | 0 | 0 |
| H/R | 22739 |
Fn3-52 |
97 | rs1170829810 |
0.8791 | -0.118 | 0.938 | N | 0.678 | 0.282 | 0.247872288689 | gnomAD-4.0.0 | 1.6001E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44559E-05 | 0 |
| H/Y | 22739 |
Fn3-52 |
97 | rs993803663 |
0.1737 | None | 0.007 | N | 0.347 | 0.226 | 0.208816687407 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 6.32911E-03 | 0 | 0 | 4.79846E-04 |
| H/Y | 22739 |
Fn3-52 |
97 | rs993803663 |
0.1737 | None | 0.007 | N | 0.347 | 0.226 | 0.208816687407 | gnomAD-4.0.0 | 8.07374E-06 | None | None | None | None | I | None | 1.33661E-05 | 0 | None | 0 | 0 | None | 0 | 1.49254E-03 | 0 | 0 | 4.81386E-05 |
| D/E | 22840 |
Fn3-53 |
98 | None | 0.8654 | None | 0.999 | N | 0.431 | 0.213 | 0.330069100803 | gnomAD-4.0.0 | 1.59428E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43831E-05 | 0 |
| D/G | 22939 |
Fn3-54 |
99 | None | 0.7686 | None | 0.032 | N | 0.385 | 0.288 | 0.215109475489 | gnomAD-4.0.0 | 6.87923E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02415E-07 | 0 | 0 |
| D/V | 22939 |
Fn3-54 |
99 | None | 0.8814 | None | 0.987 | N | 0.708 | 0.482 | 0.467669411796 | gnomAD-4.0.0 | 1.37585E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80483E-06 | 0 | 0 |
| D/G | 23236 |
Fn3-56 |
98 | None | 0.5148 | None | 0.935 | N | 0.58 | 0.214 | 0.248417906384 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/Q | 23338 |
Fn3-57 |
99 | rs78916558 |
0.1343 | 0.147 | 0.028 | D | 0.224 | 0.107 | None | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 1.24008E-04 | 8.49E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 2.35E-05 | 0 |
| R/Q | 23338 |
Fn3-57 |
99 | rs78916558 |
0.1343 | 0.147 | 0.028 | D | 0.224 | 0.107 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.93648E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/Q | 23338 |
Fn3-57 |
99 | rs78916558 |
0.1343 | 0.147 | 0.028 | D | 0.224 | 0.107 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| R/Q | 23338 |
Fn3-57 |
99 | rs78916558 |
0.1343 | 0.147 | 0.028 | D | 0.224 | 0.107 | None | gnomAD-4.0.0 | 8.67728E-06 | None | None | None | None | N | None | 1.33344E-05 | 5.00033E-05 | None | 0 | 2.23404E-05 | None | 0 | 0 | 5.93427E-06 | 1.09835E-05 | 1.60087E-05 |
| R/W | 23338 |
Fn3-57 |
99 | rs773695377 |
0.3082 | -0.352 | 0.984 | N | 0.789 | 0.332 | 0.551220473365 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.15E-05 | None | 6.54E-05 | None | 0 | 7.82E-06 | 0 |
| R/W | 23338 |
Fn3-57 |
99 | rs773695377 |
0.3082 | -0.352 | 0.984 | N | 0.789 | 0.332 | 0.551220473365 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/W | 23338 |
Fn3-57 |
99 | rs773695377 |
0.3082 | -0.352 | 0.984 | N | 0.789 | 0.332 | 0.551220473365 | gnomAD-4.0.0 | 9.29804E-06 | None | None | None | None | N | None | 1.33586E-05 | 0 | None | 0 | 2.23374E-05 | None | 0 | 0 | 9.32523E-06 | 2.1966E-05 | 0 |
| E/K | 23531 |
Fn3-58 |
97 | rs1182129747 |
0.3875 | None | 0.872 | N | 0.616 | 0.28 | 0.359357374593 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 23531 |
Fn3-58 |
97 | rs1182129747 |
0.3875 | None | 0.872 | N | 0.616 | 0.28 | 0.359357374593 | gnomAD-4.0.0 | 2.03004E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20497E-06 | 4.69836E-05 | 0 |
| Y/N | 23822 |
Fn3-60 |
97 | None | 0.4925 | None | 0.994 | N | 0.684 | 0.444 | 0.673276159487 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| Y/S | 23822 |
Fn3-60 |
97 | rs1709438613 |
0.5678 | None | 0.981 | N | 0.671 | 0.297 | 0.612832922585 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/S | 23822 |
Fn3-60 |
97 | rs1709438613 |
0.5678 | None | 0.981 | N | 0.671 | 0.297 | 0.612832922585 | gnomAD-4.0.0 | 2.47971E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39126E-06 | 0 | 0 |
| D/N | 24022 |
Fn3-62 |
99 | rs767886519 |
0.4455 | -0.226 | 1.0 | N | 0.72 | 0.338 | 0.276482976112 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.6154E-04 | None | 0 | 0 | 0 |
| N/K | 24218 |
Fn3-63 |
97 | None | 0.7761 | None | 0.115 | N | 0.748 | 0.132 | 0.137902524267 | gnomAD-4.0.0 | 1.47595E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.87968E-06 | 0 | 0 |
| N/Y | 24218 |
Fn3-63 |
97 | None | 0.3368 | None | 0.186 | N | 0.622 | 0.17 | 0.225902525712 | gnomAD-4.0.0 | 1.47592E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.87965E-06 | 0 | 0 |
| D/G | 24319 |
Fn3-64 |
98 | None | 0.7484 | None | 1.0 | N | 0.783 | 0.421 | 0.374434639691 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 24319 |
Fn3-64 |
98 | rs1241907204 |
0.2789 | 0.35 | 1.0 | N | 0.785 | 0.355 | 0.414281671643 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| D/N | 24319 |
Fn3-64 |
98 | rs1241907204 |
0.2789 | 0.35 | 1.0 | N | 0.785 | 0.355 | 0.414281671643 | gnomAD-4.0.0 | 1.597E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78118E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 24421 |
Fn3-65 |
99 | None | 0.104 | None | 0.002 | N | 0.287 | 0.05 | 0.0986583533028 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85943E-06 | 0 | 0 |
| D/N | 24421 |
Fn3-65 |
99 | None | 0.2363 | None | 0.693 | D | 0.761 | 0.257 | 0.389283895039 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| E/K | 24615 |
Fn3-66 |
97 | rs374131909 |
0.8374 | 0.223 | 0.996 | N | 0.786 | 0.372 | 0.441844919209 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| E/K | 24615 |
Fn3-66 |
97 | rs374131909 |
0.8374 | 0.223 | 0.996 | N | 0.786 | 0.372 | 0.441844919209 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 24615 |
Fn3-66 |
97 | rs374131909 |
0.8374 | 0.223 | 0.996 | N | 0.786 | 0.372 | 0.441844919209 | gnomAD-4.0.0 | 6.57557E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47054E-05 | 0 | 0 |
| E/Q | 24615 |
Fn3-66 |
97 | rs374131909 |
0.4043 | 0.088 | 0.998 | N | 0.662 | 0.275 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
| E/Q | 24615 |
Fn3-66 |
97 | rs374131909 |
0.4043 | 0.088 | 0.998 | N | 0.662 | 0.275 | None | gnomAD-4.0.0 | 1.36952E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80033E-06 | 0 | 0 |
| D/E | 24711 |
Fn3-67 |
96 | rs1708361319 |
0.6476 | None | 0.001 | N | 0.364 | 0.166 | 0.0611884634855 | gnomAD-4.0.0 | 2.0533E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69884E-06 | 0 | 0 |
| D/V | 24711 |
Fn3-67 |
96 | rs765607630 |
0.9289 | 0.351 | 0.909 | N | 0.729 | 0.503 | 0.575012909346 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 0 | 0 |
| D/V | 24711 |
Fn3-67 |
96 | rs765607630 |
0.9289 | 0.351 | 0.909 | N | 0.729 | 0.503 | 0.575012909346 | gnomAD-4.0.0 | 4.79102E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 8.11651E-05 | 0 |
| D/Y | 24711 |
Fn3-67 |
96 | rs751001455 |
0.8987 | 0.095 | 0.998 | D | 0.798 | 0.463 | 0.728531110816 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| D/Y | 24711 |
Fn3-67 |
96 | rs751001455 |
0.8987 | 0.095 | 0.998 | D | 0.798 | 0.463 | 0.728531110816 | gnomAD-4.0.0 | 1.59249E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85974E-06 | 0 | 0 |
| Y/C | 24904 |
Fn3-68 |
97 | None | 0.8178 | None | 0.994 | N | 0.867 | 0.289 | 0.551550886788 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 6.07533E-05 | 0 |
| D/A | 25005 |
Fn3-69 |
98 | rs761496228 |
0.6993 | 0.274 | 0.841 | N | 0.581 | 0.327 | 0.326881540566 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/A | 25005 |
Fn3-69 |
98 | rs761496228 |
0.6993 | 0.274 | 0.841 | N | 0.581 | 0.327 | 0.326881540566 | gnomAD-4.0.0 | 1.59194E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43291E-05 | 0 |
| D/E | 25005 |
Fn3-69 |
98 | rs2154169091 |
0.6142 | None | 0.955 | N | 0.503 | 0.114 | 0.211220785272 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88565E-05 | 0 | 0 | 0 | 0 |
| D/N | 25005 |
Fn3-69 |
98 | rs766883705 |
0.3256 | 0.545 | 0.974 | N | 0.771 | 0.334 | 0.322510055762 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65948E-04 |
| D/N | 25005 |
Fn3-69 |
98 | rs766883705 |
0.3256 | 0.545 | 0.974 | N | 0.771 | 0.334 | 0.322510055762 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77516E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 25104 |
Fn3-70 |
99 | rs534319705 |
0.9213 | 0.363 | 1.0 | N | 0.755 | 0.478 | 0.324986149311 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93274E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 25104 |
Fn3-70 |
99 | rs534319705 |
0.9213 | 0.363 | 1.0 | N | 0.755 | 0.478 | 0.324986149311 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| D/V | 25104 |
Fn3-70 |
99 | rs534319705 |
0.9213 | 0.363 | 1.0 | N | 0.755 | 0.478 | 0.324986149311 | gnomAD-4.0.0 | 1.53758E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.91305E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 25401 |
Fn3-72 |
98 | None | 0.5294 | None | 0.999 | N | 0.469 | 0.108 | 0.208816687407 | gnomAD-4.0.0 | 1.59274E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86049E-06 | 0 | 0 |
| D/V | 25401 |
Fn3-72 |
98 | rs1559385033 |
0.7042 | 0.334 | 1.0 | N | 0.759 | 0.596 | 0.376921832658 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| D/V | 25401 |
Fn3-72 |
98 | rs1559385033 |
0.7042 | 0.334 | 1.0 | N | 0.759 | 0.596 | 0.376921832658 | gnomAD-4.0.0 | 3.18564E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86812E-05 | 0 |
| E/K | 25697 |
Fn3-74 |
97 | rs754291492 |
0.5909 | 0.391 | 0.996 | N | 0.817 | 0.398 | 0.476127810785 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| E/K | 25697 |
Fn3-74 |
97 | rs754291492 |
0.5909 | 0.391 | 0.996 | N | 0.817 | 0.398 | 0.476127810785 | gnomAD-4.0.0 | 3.42208E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49823E-06 | 0 | 0 |
| E/V | 25697 |
Fn3-74 |
97 | rs764509751 |
0.5633 | 0.288 | 0.997 | N | 0.751 | 0.588 | 0.612105117874 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| E/V | 25697 |
Fn3-74 |
97 | rs764509751 |
0.5633 | 0.288 | 0.997 | N | 0.751 | 0.588 | 0.612105117874 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/V | 25697 |
Fn3-74 |
97 | rs764509751 |
0.5633 | 0.288 | 0.997 | N | 0.751 | 0.588 | 0.612105117874 | gnomAD-4.0.0 | 1.85966E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.38089E-05 | 0 | None | 0 | 0 | 1.69559E-06 | 0 | 0 |
| Y/H | 25986 |
Fn3-76 |
97 | rs1706668829 |
0.5705 | None | 0.988 | N | 0.587 | 0.256 | 0.324986149311 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| D/V | 26087 |
Fn3-77 |
98 | rs1462639599 |
0.8335 | 0.382 | 1.0 | N | 0.773 | 0.64 | 0.534191878353 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/V | 26087 |
Fn3-77 |
98 | rs1462639599 |
0.8335 | 0.382 | 1.0 | N | 0.773 | 0.64 | 0.534191878353 | gnomAD-4.0.0 | 1.59178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| D/Y | 26087 |
Fn3-77 |
98 | rs1169880412 |
0.7103 | 0.122 | 1.0 | N | 0.817 | 0.609 | 0.594452868026 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.88E-06 | 0 |
| D/Y | 26087 |
Fn3-77 |
98 | rs1169880412 |
0.7103 | 0.122 | 1.0 | N | 0.817 | 0.609 | 0.594452868026 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/Y | 26087 |
Fn3-77 |
98 | rs1169880412 |
0.7103 | 0.122 | 1.0 | N | 0.817 | 0.609 | 0.594452868026 | gnomAD-4.0.0 | 4.95844E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93423E-06 | 1.09791E-05 | 0 |
| N/D | 26382 |
Fn3-79 |
97 | rs751896572 |
0.2541 | -0.048 | 0.955 | N | 0.563 | 0.253 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| N/D | 26382 |
Fn3-79 |
97 | rs751896572 |
0.2541 | -0.048 | 0.955 | N | 0.563 | 0.253 | None | gnomAD-4.0.0 | 2.73708E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59822E-06 | 0 | 0 |
| N/H | 26382 |
Fn3-79 |
97 | rs751896572 |
0.4619 | -0.763 | 0.987 | N | 0.549 | 0.277 | 0.218845423259 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| N/H | 26382 |
Fn3-79 |
97 | rs751896572 |
0.4619 | -0.763 | 0.987 | N | 0.549 | 0.277 | 0.218845423259 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/H | 26382 |
Fn3-79 |
97 | rs751896572 |
0.4619 | -0.763 | 0.987 | N | 0.549 | 0.277 | 0.218845423259 | gnomAD-4.0.0 | 4.33842E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93393E-06 | 0 | 0 |
| N/T | 26382 |
Fn3-79 |
97 | rs727505049 |
0.6144 | 0.178 | 0.914 | N | 0.569 | 0.208 | 0.225215365344 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| N/T | 26382 |
Fn3-79 |
97 | rs727505049 |
0.6144 | 0.178 | 0.914 | N | 0.569 | 0.208 | 0.225215365344 | gnomAD-4.0.0 | 5.47414E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19642E-06 | 0 | 0 |
| D/N | 26585 |
Fn3-81 |
99 | rs771202190 |
0.2995 | None | 0.964 | N | 0.582 | 0.307 | 0.390687800842 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| E/D | 26779 |
Fn3-82 |
97 | rs760599182 |
0.2593 | -0.12 | None | N | 0.361 | 0.033 | 0.223847106136 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/D | 26779 |
Fn3-82 |
97 | rs760599182 |
0.2593 | -0.12 | None | N | 0.361 | 0.033 | 0.223847106136 | gnomAD-4.0.0 | 6.36647E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.73115E-05 | 0 |
| D/H | 26875 |
Fn3-83 |
96 | rs1422715847 |
0.7842 | 0.328 | 1.0 | N | 0.875 | 0.696 | 0.446813524615 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/H | 26875 |
Fn3-83 |
96 | rs1422715847 |
0.7842 | 0.328 | 1.0 | N | 0.875 | 0.696 | 0.446813524615 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 26875 |
Fn3-83 |
96 | rs1422715847 |
0.7842 | 0.328 | 1.0 | N | 0.875 | 0.696 | 0.446813524615 | gnomAD-4.0.0 | 2.47943E-06 | None | None | None | None | N | None | 4.00727E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60164E-05 |
| D/V | 26875 |
Fn3-83 |
96 | None | 0.6521 | None | 0.999 | D | 0.799 | 0.739 | 0.770370076884 | gnomAD-4.0.0 | 1.20036E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31255E-06 | 0 | 0 |
| D/Y | 26875 |
Fn3-83 |
96 | rs1422715847 |
0.6405 | None | 1.0 | N | 0.832 | 0.738 | 0.758986609867 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/Y | 26875 |
Fn3-83 |
96 | rs1422715847 |
0.6405 | None | 1.0 | N | 0.832 | 0.738 | 0.758986609867 | gnomAD-4.0.0 | 1.23972E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69554E-06 | 0 | 0 |
| Y/H | 27068 |
Fn3-84 |
97 | None | 0.4824 | None | 0.015 | N | 0.334 | 0.217 | 0.24896430686 | gnomAD-4.0.0 | 1.59509E-06 | None | None | None | None | N | None | 5.70972E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 27465 |
Fn3-87 |
97 | None | 0.2157 | None | 0.938 | N | 0.605 | 0.323 | 0.318252033908 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/C | 28150 |
Fn3-92 |
96 | None | 0.6732 | None | 1.0 | N | 0.769 | 0.274 | 0.575279034457 | gnomAD-4.0.0 | 1.60752E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89064E-06 | 0 | 0 |
| Y/H | 28150 |
Fn3-92 |
96 | rs397517727 |
0.4533 | 0.596 | 1.0 | N | 0.645 | 0.212 | 0.377976839388 | gnomAD-2.1.1 | 9.83E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 8.10975E-04 | None | 0 | 0 | 0 |
| Y/H | 28150 |
Fn3-92 |
96 | rs397517727 |
0.4533 | 0.596 | 1.0 | N | 0.645 | 0.212 | 0.377976839388 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| Y/H | 28150 |
Fn3-92 |
96 | rs397517727 |
0.4533 | 0.596 | 1.0 | N | 0.645 | 0.212 | 0.377976839388 | 1000 genomes | 3.99361E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 2E-03 | None |
| Y/H | 28150 |
Fn3-92 |
96 | rs397517727 |
0.4533 | 0.596 | 1.0 | N | 0.645 | 0.212 | 0.377976839388 | gnomAD-4.0.0 | 3.73312E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.66058E-04 | 0 | 6.20059E-04 | 4.82455E-05 |
| D/E | 28251 |
Fn3-93 |
98 | None | 0.766 | None | 0.999 | N | 0.489 | 0.203 | 0.27855597813 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 28251 |
Fn3-93 |
98 | None | 0.4398 | None | 1.0 | N | 0.793 | 0.368 | 0.418964662724 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 28350 |
Fn3-94 |
99 | rs1337835797 |
0.6846 | 0.455 | 1.0 | N | 0.783 | 0.311 | 0.415947407303 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| D/N | 28350 |
Fn3-94 |
99 | rs1337835797 |
0.6846 | 0.455 | 1.0 | N | 0.783 | 0.311 | 0.415947407303 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/N | 28350 |
Fn3-94 |
99 | rs1337835797 |
0.6846 | 0.455 | 1.0 | N | 0.783 | 0.311 | 0.415947407303 | gnomAD-4.0.0 | 6.57168E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47016E-05 | 0 | 0 |
| D/N | 28546 |
Fn3-95 |
97 | rs771897496 |
0.1557 | 0.536 | None | N | 0.306 | 0.096 | 0.162503812791 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| D/N | 28546 |
Fn3-95 |
97 | rs771897496 |
0.1557 | 0.536 | None | N | 0.306 | 0.096 | 0.162503812791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07383E-04 | 0 |
| D/N | 28546 |
Fn3-95 |
97 | rs771897496 |
0.1557 | 0.536 | None | N | 0.306 | 0.096 | 0.162503812791 | gnomAD-4.0.0 | 3.84715E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.0235E-05 | 0 |
| D/V | 28546 |
Fn3-95 |
97 | None | 0.5464 | None | 0.001 | N | 0.505 | 0.39 | 0.546174653742 | gnomAD-4.0.0 | 1.59289E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86058E-06 | 0 | 0 |
| D/N | 28647 |
Fn3-96 |
98 | rs1378020700 |
0.3932 | None | 1.0 | N | 0.791 | 0.308 | 0.286081765059 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/N | 28647 |
Fn3-96 |
98 | rs1378020700 |
0.3932 | None | 1.0 | N | 0.791 | 0.308 | 0.286081765059 | gnomAD-4.0.0 | 7.105E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.22965E-06 | 0 | 3.40252E-05 |
| E/D | 28941 |
Fn3-98 |
97 | rs1702394454 |
0.4912 | None | 0.946 | N | 0.512 | None | 0.385743280973 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/D | 28941 |
Fn3-98 |
97 | rs1702394454 |
0.4912 | None | 0.946 | N | 0.512 | None | 0.385743280973 | gnomAD-4.0.0 | 2.57384E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.79203E-06 | 0 | 0 |
| E/K | 28941 |
Fn3-98 |
97 | None | 0.5195 | None | 0.996 | N | 0.646 | 0.355 | 0.440915056915 | gnomAD-4.0.0 | 1.67668E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.99442E-06 | 0 | 0 |
| E/G | 29037 |
Fn3-99 |
96 | None | 0.1895 | None | 0.115 | N | 0.649 | 0.305 | 0.39798585902 | gnomAD-4.0.0 | 1.59821E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78474E-05 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 29233 |
Fn3-100 |
97 | rs1702051933 |
0.2719 | None | 0.997 | N | 0.561 | 0.163 | 0.546952355657 | gnomAD-4.0.0 | 1.59143E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02425E-05 |
| D/H | 29433 |
Fn3-102 |
99 | rs189202799 |
0.822 | 0.482 | 0.994 | N | 0.833 | 0.359 | 0.275215494804 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/H | 29433 |
Fn3-102 |
99 | rs189202799 |
0.822 | 0.482 | 0.994 | N | 0.833 | 0.359 | 0.275215494804 | gnomAD-4.0.0 | 6.84408E-07 | None | None | None | None | N | None | 2.98739E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 29433 |
Fn3-102 |
99 | rs189202799 |
0.394 | 0.412 | 0.979 | N | 0.785 | 0.348 | None | gnomAD-2.1.1 | 4.50763E-04 | None | None | None | None | N | None | 4.46355E-03 | 3.39732E-04 | None | 0 | 0 | None | 0 | None | 0 | 3.91E-05 | 1.40607E-04 |
| D/N | 29433 |
Fn3-102 |
99 | rs189202799 |
0.394 | 0.412 | 0.979 | N | 0.785 | 0.348 | None | gnomAD-3.1.2 | 1.39347E-03 | None | None | None | None | N | None | 4.58627E-03 | 6.54707E-04 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 3.83142E-03 |
| D/N | 29433 |
Fn3-102 |
99 | rs189202799 |
0.394 | 0.412 | 0.979 | N | 0.785 | 0.348 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | N | None | 4.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/N | 29433 |
Fn3-102 |
99 | rs189202799 |
0.394 | 0.412 | 0.979 | N | 0.785 | 0.348 | None | gnomAD-4.0.0 | 2.70861E-04 | None | None | None | None | N | None | 4.6785E-03 | 4.33276E-04 | None | 6.75813E-05 | 0 | None | 0 | 1.65125E-04 | 2.71237E-05 | 1.09825E-05 | 3.84172E-04 |
| N/K | 29629 |
Fn3-103 |
97 | rs759136146 |
0.9385 | None | 1.0 | N | 0.757 | 0.235 | 0.104622674875 | gnomAD-4.0.0 | 4.79221E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29798E-06 | 0 | 0 |
| E/V | 30124 |
Fn3-107 |
95 | None | 0.7848 | None | 0.966 | N | 0.577 | 0.354 | 0.496036935653 | gnomAD-4.0.0 | 1.5914E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85827E-06 | 0 | 0 |
| H/R | 30320 |
Fn3-108 |
97 | rs1244743041 |
0.6823 | 0.028 | 0.999 | D | 0.672 | 0.413 | 0.360565625551 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 30320 |
Fn3-108 |
97 | rs1244743041 |
0.6823 | 0.028 | 0.999 | D | 0.672 | 0.413 | 0.360565625551 | gnomAD-4.0.0 | 6.19918E-06 | None | None | None | None | N | None | 2.6698E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78369E-06 | 0 | 0 |
| S/A | 30421 |
Fn3-109 |
98 | None | 0.1851 | None | 0.994 | N | 0.536 | 0.197 | 0.184867976434 | gnomAD-4.0.0 | 1.68656E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.92419E-05 | 0 | 0 | 0 | 0 |
| S/P | 30421 |
Fn3-109 |
98 | rs1699486002 |
0.5917 | None | 0.999 | N | 0.642 | 0.372 | 0.301789629655 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 30421 |
Fn3-109 |
98 | rs1699486002 |
0.5917 | None | 0.999 | N | 0.642 | 0.372 | 0.301789629655 | gnomAD-4.0.0 | 6.57065E-06 | None | None | None | None | I | None | 0 | 6.54793E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 30519 |
Fn3-110 |
98 | rs202185465 |
0.6096 | 0.076 | 0.999 | N | 0.505 | 0.16 | 0.239305524855 | gnomAD-2.1.1 | 7.19E-06 | None | None | None | None | N | None | 8.28E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 30519 |
Fn3-110 |
98 | rs202185465 |
0.6096 | 0.076 | 0.999 | N | 0.505 | 0.16 | 0.239305524855 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 30519 |
Fn3-110 |
98 | rs202185465 |
0.6096 | 0.076 | 0.999 | N | 0.505 | 0.16 | 0.239305524855 | gnomAD-4.0.0 | 2.62919E-05 | None | None | None | None | N | None | 9.65158E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 30519 |
Fn3-110 |
98 | None | 0.8368 | None | 1.0 | N | 0.823 | 0.418 | 0.759054169798 | gnomAD-4.0.0 | 6.8475E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65772E-05 |
| I/M | 30715 |
Fn3-111 |
97 | rs767562959 |
0.0875 | -0.485 | 0.068 | N | 0.269 | 0.046 | 0.376216005999 | gnomAD-2.1.1 | 1.8E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.56279E-04 | None | 0 | None | 0 | 0 | 0 |
| I/M | 30715 |
Fn3-111 |
97 | rs767562959 |
0.0875 | -0.485 | 0.068 | N | 0.269 | 0.046 | 0.376216005999 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.84615E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 30715 |
Fn3-111 |
97 | rs767562959 |
0.0875 | -0.485 | 0.068 | N | 0.269 | 0.046 | 0.376216005999 | gnomAD-4.0.0 | 4.34188E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.33738E-04 | None | 0 | 0 | 0 | 0 | 1.60251E-05 |
| I/T | 30715 |
Fn3-111 |
97 | None | 0.3422 | None | 0.651 | N | 0.422 | 0.222 | 0.416454006429 | gnomAD-4.0.0 | 1.59504E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77531E-05 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 30817 |
Fn3-112 |
99 | rs397517755 |
0.1512 | -0.065 | 0.007 | N | 0.345 | 0.036 | 0.104622674875 | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 7.03E-05 | 0 |
| E/D | 30817 |
Fn3-112 |
99 | rs397517755 |
0.1512 | -0.065 | 0.007 | N | 0.345 | 0.036 | 0.104622674875 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 8.82E-05 | 0 | 0 |
| E/D | 30817 |
Fn3-112 |
99 | rs397517755 |
0.1512 | -0.065 | 0.007 | N | 0.345 | 0.036 | 0.104622674875 | gnomAD-4.0.0 | 7.12671E-05 | None | None | None | None | N | None | 0 | 3.33489E-05 | None | 0 | 0 | None | 0 | 0 | 9.49299E-05 | 0 | 1.60133E-05 |
| E/K | 30817 |
Fn3-112 |
99 | rs529196025 |
0.3362 | 0.725 | 0.007 | N | 0.478 | 0.158 | 0.194818534648 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 30817 |
Fn3-112 |
99 | rs529196025 |
0.3362 | 0.725 | 0.007 | N | 0.478 | 0.158 | 0.194818534648 | gnomAD-4.0.0 | 6.84219E-07 | None | None | None | None | N | None | 2.98775E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 30817 |
Fn3-112 |
99 | rs529196025 |
0.2266 | 0.49 | 0.79 | N | 0.539 | 0.094 | 0.210429274316 | gnomAD-2.1.1 | 3.21E-05 | None | None | None | None | N | None | 0 | 8.5E-05 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 7.81E-06 | 2.80899E-04 |
| E/Q | 30817 |
Fn3-112 |
99 | rs529196025 |
0.2266 | 0.49 | 0.79 | N | 0.539 | 0.094 | 0.210429274316 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 2.07383E-04 | 0 |
| E/Q | 30817 |
Fn3-112 |
99 | rs529196025 |
0.2266 | 0.49 | 0.79 | N | 0.539 | 0.094 | 0.210429274316 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| E/Q | 30817 |
Fn3-112 |
99 | rs529196025 |
0.2266 | 0.49 | 0.79 | N | 0.539 | 0.094 | 0.210429274316 | gnomAD-4.0.0 | 1.17737E-05 | None | None | None | None | N | None | 0 | 1.16694E-04 | None | 0 | 0 | None | 0 | 0 | 4.23798E-06 | 5.48992E-05 | 3.20154E-05 |
| D/Y | 30918 |
Fn3-113 |
98 | rs781654770 |
0.8278 | 0.12 | 1.0 | N | 0.831 | 0.58 | 0.73377832567 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| D/Y | 30918 |
Fn3-113 |
98 | rs781654770 |
0.8278 | 0.12 | 1.0 | N | 0.831 | 0.58 | 0.73377832567 | gnomAD-4.0.0 | 6.1582E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09497E-06 | 0 | 0 |
| E/D | 31112 |
Fn3-114 |
97 | None | 0.5372 | None | 0.997 | N | 0.531 | 0.088 | 0.211220785272 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 31112 |
Fn3-114 |
97 | rs367766603 |
0.5909 | 0.676 | 0.997 | N | 0.684 | 0.308 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| E/K | 31112 |
Fn3-114 |
97 | rs367766603 |
0.5909 | 0.676 | 0.997 | N | 0.684 | 0.308 | None | gnomAD-4.0.0 | 1.36835E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79888E-06 | 0 | 0 |
| E/Q | 31112 |
Fn3-114 |
97 | None | 0.2912 | None | 0.999 | N | 0.637 | 0.208 | 0.220303561663 | gnomAD-4.0.0 | 6.84177E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99439E-07 | 0 | 0 |
| E/D | 31208 |
Fn3-115 |
96 | None | 0.2173 | None | 0.018 | N | 0.337 | 0.094 | 0.201204373187 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| E/K | 31208 |
Fn3-115 |
96 | rs765216493 |
0.7582 | 0.746 | 0.856 | N | 0.666 | 0.332 | 0.318828661733 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/K | 31208 |
Fn3-115 |
96 | rs765216493 |
0.7582 | 0.746 | 0.856 | N | 0.666 | 0.332 | 0.318828661733 | gnomAD-4.0.0 | 1.59142E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| H/N | 31404 |
Fn3-116 |
97 | rs1409641656 |
0.397 | 0.215 | 0.997 | N | 0.622 | 0.329 | 0.271763555656 | gnomAD-4.0.0 | 1.63067E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.46619E-05 | 0 |
| N/T | 31505 |
Fn3-117 |
98 | rs755756435 |
0.3732 | 0.437 | 0.997 | N | 0.723 | 0.285 | 0.380564188046 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 9.94E-05 | None | 0 | 0 | 0 |
| N/T | 31505 |
Fn3-117 |
98 | rs755756435 |
0.3732 | 0.437 | 0.997 | N | 0.723 | 0.285 | 0.380564188046 | gnomAD-4.0.0 | 3.43351E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.82099E-05 | 0 |
| D/N | 31607 |
Fn3-118 |
102 | None | 0.5553 | None | 1.0 | N | 0.762 | 0.279 | 0.396645960531 | gnomAD-4.0.0 | 3.20977E-06 | None | None | None | None | N | None | 0 | 2.29274E-05 | None | 0 | 0 | None | 0 | 0 | 2.89337E-06 | 0 | 0 |
| N/T | 31803 |
Fn3-119 |
96 | rs2154145420 |
0.4565 | None | 0.997 | N | 0.711 | 0.336 | 0.349429436713 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 0 | 0 | 0 |
| E/Q | 31905 |
Fn3-120 |
99 | rs777381153 |
0.2307 | 0.395 | 0.993 | N | 0.628 | 0.229 | 0.216624796971 | gnomAD-2.1.1 | 4.5E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.13E-05 | None | 0 | 0 | 0 |
| E/Q | 31905 |
Fn3-120 |
99 | rs777381153 |
0.2307 | 0.395 | 0.993 | N | 0.628 | 0.229 | 0.216624796971 | gnomAD-4.0.0 | 2.11808E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.78444E-05 | 0 |
| E/D | 32007 |
Fn3-121 |
99 | rs569522219 |
0.1704 | -0.105 | 0.997 | N | 0.595 | 0.144 | 0.281381271821 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/D | 32007 |
Fn3-121 |
99 | rs569522219 |
0.1704 | -0.105 | 0.997 | N | 0.595 | 0.144 | 0.281381271821 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 32007 |
Fn3-121 |
99 | rs569522219 |
0.1704 | -0.105 | 0.997 | N | 0.595 | 0.144 | 0.281381271821 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/D | 32007 |
Fn3-121 |
99 | rs569522219 |
0.1704 | -0.105 | 0.997 | N | 0.595 | 0.144 | 0.281381271821 | gnomAD-4.0.0 | 6.56521E-06 | None | None | None | None | N | None | 2.40523E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 32007 |
Fn3-121 |
99 | rs1205390409 |
0.5795 | None | 0.999 | N | 0.622 | 0.473 | 0.608345586348 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/G | 32007 |
Fn3-121 |
99 | rs1205390409 |
0.5795 | None | 0.999 | N | 0.622 | 0.473 | 0.608345586348 | gnomAD-4.0.0 | 6.57039E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47003E-05 | 0 | 0 |
| S/G | 32495 |
Fn3-124 |
97 | rs1328086725 |
0.1888 | -0.875 | 0.997 | N | 0.53 | 0.227 | 0.395894371353 | gnomAD-2.1.1 | 4.14E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.17E-06 | 0 |
| D/Y | 32596 |
Fn3-125 |
98 | None | 0.6086 | None | 1.0 | N | 0.853 | 0.404 | 0.710160429546 | gnomAD-4.0.0 | 1.91882E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.835E-05 | 0 |
| E/D | 32697 |
Fn3-126 |
98 | rs748057839 |
0.317 | -0.025 | 0.997 | N | 0.586 | 0.142 | 0.274366138417 | gnomAD-2.1.1 | 2.95E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.11862E-04 | None | 0 | None | 0 | 0 | 0 |
| E/D | 32697 |
Fn3-126 |
98 | rs748057839 |
0.317 | -0.025 | 0.997 | N | 0.586 | 0.142 | 0.274366138417 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 32697 |
Fn3-126 |
98 | rs748057839 |
0.317 | -0.025 | 0.997 | N | 0.586 | 0.142 | 0.274366138417 | gnomAD-4.0.0 | 6.25188E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.01279E-04 | None | 0 | 0 | 0 | 0 | 1.61943E-05 |
| T/A | 32892 |
Fn3-127 |
98 | None | 0.145 | None | 0.997 | N | 0.691 | 0.271 | 0.259272394797 | gnomAD-4.0.0 | 1.59916E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4346E-05 | 0 |
| D/E | 32994 |
Fn3-128 |
99 | None | 0.5687 | None | 0.999 | N | 0.555 | 0.247 | 0.242244723065 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/G | 33388 |
Fn3-130 |
99 | None | 0.2236 | None | 0.181 | N | 0.463 | 0.08 | 0.126345400529 | gnomAD-4.0.0 | 1.61255E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.90781E-06 | 0 | 0 |
| S/N | 33388 |
Fn3-130 |
99 | rs745406517 |
0.217 | 0.018 | 0.181 | N | 0.507 | 0.074 | None | gnomAD-2.1.1 | 1.09E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.38E-05 | 0 |
| S/N | 33388 |
Fn3-130 |
99 | rs745406517 |
0.217 | 0.018 | 0.181 | N | 0.507 | 0.074 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| S/N | 33388 |
Fn3-130 |
99 | rs745406517 |
0.217 | 0.018 | 0.181 | N | 0.507 | 0.074 | None | gnomAD-4.0.0 | 1.12185E-05 | None | None | None | None | I | None | 1.33765E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.44892E-05 | 0 | 0 |
| S/R | 33388 |
Fn3-130 |
99 | None | 0.8802 | None | 0.437 | N | 0.518 | 0.177 | 0.262175524916 | gnomAD-4.0.0 | 2.40094E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62532E-06 | 0 | 0 |
| S/A | 33489 |
Fn3-131 |
98 | None | 0.0951 | None | 0.893 | N | 0.563 | 0.163 | 0.225215365344 | gnomAD-4.0.0 | 1.59163E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85858E-06 | 0 | 0 |
| S/C | 33489 |
Fn3-131 |
98 | None | 0.2081 | None | 0.999 | D | 0.483 | 0.419 | 0.463758542814 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| E/Q | 33784 |
Fn3-132 |
96 | rs918368881 |
0.6249 | 0.412 | 0.996 | N | 0.602 | 0.25 | 0.292062946507 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 1.17924E-03 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 33784 |
Fn3-132 |
96 | rs918368881 |
0.6249 | 0.412 | 0.996 | N | 0.602 | 0.25 | 0.292062946507 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.31027E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 33784 |
Fn3-132 |
96 | rs918368881 |
0.6249 | 0.412 | 0.996 | N | 0.602 | 0.25 | 0.292062946507 | gnomAD-4.0.0 | 1.31453E-05 | None | None | None | None | N | None | 0 | 1.31027E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.