Structural position:
- Domain Type: Fn3
- Aligned Position: 14
- Secondary Structure Element: e
- Secondary Structure Region: β-strand A
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| D/H | 15769 |
Fn3-2 |
12 | None | 0.2909 | None | 1.0 | D | 0.671 | 0.387 | 0.348983352498 | gnomAD-4.0.0 | 1.59432E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43365E-05 | 0 |
| D/H | 15870 |
Fn3-3 |
12 | None | 0.2477 | None | 0.931 | D | 0.667 | 0.307 | 0.275215494804 | gnomAD-4.0.0 | 1.63927E-06 | None | None | None | None | N | None | 0 | 2.58345E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 16166 |
Fn3-5 |
12 | rs1429263816 |
0.2967 | None | 0.977 | N | 0.38 | 0.279 | 0.304435445954 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| D/E | 16166 |
Fn3-5 |
12 | rs1429263816 |
0.2967 | None | 0.977 | N | 0.38 | 0.279 | 0.304435445954 | gnomAD-4.0.0 | 6.2024E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.48231E-06 | 0 | 0 |
| D/G | 16166 |
Fn3-5 |
12 | rs2154206145 |
0.3629 | None | 0.955 | D | 0.565 | 0.41 | 0.338592109245 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 16166 |
Fn3-5 |
12 | None | 0.1459 | None | 0.235 | N | 0.295 | 0.127 | 0.276898752692 | gnomAD-4.0.0 | 1.59421E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86436E-06 | 0 | 0 |
| D/A | 16362 |
Fn3-6 |
12 | rs1380942594 |
0.1577 | None | 0.027 | N | 0.301 | 0.274 | 0.295974979623 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/A | 16362 |
Fn3-6 |
12 | rs1380942594 |
0.1577 | None | 0.027 | N | 0.301 | 0.274 | 0.295974979623 | gnomAD-4.0.0 | 2.03042E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.41018E-06 | 0 | 0 |
| D/E | 16362 |
Fn3-6 |
12 | None | 0.0927 | None | None | N | 0.055 | 0.13 | 0.0297737177859 | gnomAD-4.0.0 | 6.8459E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9981E-07 | 0 | 0 |
| D/V | 16362 |
Fn3-6 |
12 | None | 0.2881 | None | 0.117 | D | 0.379 | 0.364 | 0.351614576976 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/G | 16461 |
Fn3-7 |
12 | None | 0.694 | None | 0.977 | D | 0.639 | 0.402 | 0.328752806141 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/D | 16662 |
Fn3-9 |
12 | rs2056522991 |
0.3605 | None | 0.978 | N | 0.471 | 0.357 | 0.181679512989 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/D | 16662 |
Fn3-9 |
12 | rs2056522991 |
0.3605 | None | 0.978 | N | 0.471 | 0.357 | 0.181679512989 | gnomAD-4.0.0 | 6.58623E-06 | None | None | None | None | N | None | 0 | 6.56254E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 16662 |
Fn3-9 |
12 | rs36043230 |
0.1114 | 0.074 | 0.63 | N | 0.166 | 0.133 | 0.128392430309 | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 6.61E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/S | 16662 |
Fn3-9 |
12 | rs36043230 |
0.1114 | 0.074 | 0.63 | N | 0.166 | 0.133 | 0.128392430309 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.42E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 16662 |
Fn3-9 |
12 | rs36043230 |
0.1114 | 0.074 | 0.63 | N | 0.166 | 0.133 | 0.128392430309 | gnomAD-4.0.0 | 1.86158E-06 | None | None | None | None | N | None | 2.67373E-05 | 1.67107E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/T | 16662 |
Fn3-9 |
12 | rs36043230 |
0.2553 | 0.272 | 0.956 | N | 0.465 | 0.328 | None | gnomAD-2.1.1 | 1.57647E-02 | None | None | None | None | N | None | 2.89551E-03 | 9.19212E-03 | None | 5.50089E-02 | 5.24E-05 | None | 7.7652E-03 | None | 1.42456E-02 | 2.1363E-02 | 1.94675E-02 |
| N/T | 16662 |
Fn3-9 |
12 | rs36043230 |
0.2553 | 0.272 | 0.956 | N | 0.465 | 0.328 | None | gnomAD-3.1.2 | 1.43738E-02 | None | None | None | None | N | None | 3.62336E-03 | 1.10265E-02 | 4.38597E-03 | 5.33449E-02 | 0 | None | 1.39754E-02 | 2.8481E-02 | 2.12475E-02 | 6.42354E-03 | 2.15517E-02 |
| N/T | 16662 |
Fn3-9 |
12 | rs36043230 |
0.2553 | 0.272 | 0.956 | N | 0.465 | 0.328 | None | 1000 genomes | 6.38978E-03 | None | None | None | None | N | None | 2.3E-03 | 8.6E-03 | None | None | 0 | 1.69E-02 | None | None | None | 6.1E-03 | None |
| N/T | 16662 |
Fn3-9 |
12 | rs36043230 |
0.2553 | 0.272 | 0.956 | N | 0.465 | 0.328 | None | gnomAD-4.0.0 | 1.95167E-02 | None | None | None | None | N | None | 3.33672E-03 | 1.0441E-02 | None | 5.31584E-02 | 2.24578E-05 | None | 1.42754E-02 | 3.25728E-02 | 2.1871E-02 | 8.08048E-03 | 2.20954E-02 |
| D/N | 16762 |
Fn3-10 |
12 | None | 0.1539 | None | 0.801 | N | 0.393 | 0.282 | 0.299427821978 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/H | 16863 |
Fn3-11 |
12 | rs1427198480 |
0.7059 | -0.072 | 1.0 | D | 0.628 | 0.458 | 0.381580015636 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| D/H | 16863 |
Fn3-11 |
12 | rs1427198480 |
0.7059 | -0.072 | 1.0 | D | 0.628 | 0.458 | 0.381580015636 | gnomAD-4.0.0 | 1.59295E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86112E-06 | 0 | 0 |
| D/N | 16863 |
Fn3-11 |
12 | rs1427198480 |
0.2293 | None | 0.98 | N | 0.542 | 0.363 | 0.262662153117 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 16863 |
Fn3-11 |
12 | rs1427198480 |
0.2293 | None | 0.98 | N | 0.542 | 0.363 | 0.262662153117 | gnomAD-4.0.0 | 6.57765E-06 | None | None | None | None | N | None | 2.41243E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 17058 |
Fn3-12 |
12 | None | 0.6535 | None | 0.667 | N | 0.606 | 0.395 | 0.32082282376 | gnomAD-4.0.0 | 2.73867E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59971E-06 | 0 | 0 |
| D/N | 17058 |
Fn3-12 |
12 | None | 0.1841 | None | 0.22 | N | 0.566 | 0.277 | 0.253726318573 | gnomAD-4.0.0 | 3.42334E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49964E-06 | 0 | 0 |
| D/G | 17380 |
Fn3-14 |
12 | rs373305248 |
0.2947 | -0.575 | 0.822 | N | 0.548 | 0.415 | 0.213573922156 | gnomAD-2.1.1 | 8.09E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| D/G | 17380 |
Fn3-14 |
12 | rs373305248 |
0.2947 | -0.575 | 0.822 | N | 0.548 | 0.415 | 0.213573922156 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94628E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/G | 17380 |
Fn3-14 |
12 | rs373305248 |
0.2947 | -0.575 | 0.822 | N | 0.548 | 0.415 | 0.213573922156 | gnomAD-4.0.0 | 2.48228E-06 | None | None | None | None | N | None | 0 | 1.668E-05 | None | 0 | 4.47227E-05 | None | 0 | 0 | 0 | 1.0983E-05 | 0 |
| D/N | 17380 |
Fn3-14 |
12 | rs886042593 |
0.1615 | None | 0.822 | N | 0.541 | 0.295 | 0.187945064343 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.78927E-04 |
| D/N | 17380 |
Fn3-14 |
12 | rs886042593 |
0.1615 | None | 0.822 | N | 0.541 | 0.295 | 0.187945064343 | gnomAD-4.0.0 | 1.316E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47184E-05 | 0 | 4.78927E-04 |
| D/V | 17380 |
Fn3-14 |
12 | rs373305248 |
0.4635 | 0.412 | 0.942 | N | 0.642 | 0.504 | None | gnomAD-2.1.1 | 7.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.41101E-04 | 2.82008E-04 |
| D/V | 17380 |
Fn3-14 |
12 | rs373305248 |
0.4635 | 0.412 | 0.942 | N | 0.642 | 0.504 | None | gnomAD-3.1.2 | 7.24E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.61893E-04 | 0 | 0 |
| D/V | 17380 |
Fn3-14 |
12 | rs373305248 |
0.4635 | 0.412 | 0.942 | N | 0.642 | 0.504 | None | gnomAD-4.0.0 | 9.30923E-05 | None | None | None | None | N | None | 1.33665E-05 | 1.66856E-05 | None | 0 | 0 | None | 0 | 0 | 1.24662E-04 | 0 | 1.60308E-05 |
| D/E | 17481 |
Fn3-15 |
12 | None | 0.1443 | None | 0.117 | N | 0.237 | 0.028 | 0.110078149338 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| D/G | 17481 |
Fn3-15 |
12 | rs773362408 |
0.1282 | -0.214 | 0.977 | N | 0.632 | 0.492 | 0.257292322809 | gnomAD-2.1.1 | 1.26E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.02733E-04 | None | 0 | 0 | 0 |
| D/G | 17481 |
Fn3-15 |
12 | rs773362408 |
0.1282 | -0.214 | 0.977 | N | 0.632 | 0.492 | 0.257292322809 | gnomAD-4.0.0 | 3.43631E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.86497E-05 | 0 |
| D/H | 17481 |
Fn3-15 |
12 | rs975141016 |
0.2952 | None | 0.999 | N | 0.621 | 0.449 | 0.296329037015 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 17481 |
Fn3-15 |
12 | rs975141016 |
0.2952 | None | 0.999 | N | 0.621 | 0.449 | 0.296329037015 | gnomAD-4.0.0 | 3.87762E-06 | None | None | None | None | N | None | 5.08889E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 17873 |
Fn3-18 |
12 | None | 0.736 | None | 1.0 | N | 0.593 | 0.502 | 0.464183351471 | gnomAD-4.0.0 | 4.8694E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.76834E-06 | 0 | 0 |
| E/Q | 17873 |
Fn3-18 |
12 | None | 0.5833 | None | 1.0 | N | 0.583 | 0.281 | 0.302459207581 | gnomAD-4.0.0 | 3.24992E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.60036E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 18076 |
Fn3-19 |
12 | rs1250676624 |
0.2002 | None | 0.122 | N | 0.115 | 0.199 | 0.17948927462 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/N | 18076 |
Fn3-19 |
12 | rs1250676624 |
0.2002 | None | 0.122 | N | 0.115 | 0.199 | 0.17948927462 | gnomAD-4.0.0 | 2.03057E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.4102E-06 | 0 | 0 |
| A/P | 18177 |
Fn3-20 |
12 | rs373546809 |
0.7234 | -0.4 | 0.003 | N | 0.316 | 0.164 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/P | 18177 |
Fn3-20 |
12 | rs373546809 |
0.7234 | -0.4 | 0.003 | N | 0.316 | 0.164 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/P | 18177 |
Fn3-20 |
12 | rs373546809 |
0.7234 | -0.4 | 0.003 | N | 0.316 | 0.164 | None | gnomAD-4.0.0 | 6.58233E-06 | None | None | None | None | N | None | 2.41604E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 18177 |
Fn3-20 |
12 | None | 0.0922 | None | 0.001 | N | 0.243 | 0.143 | 0.21279746466 | gnomAD-4.0.0 | 1.59486E-06 | None | None | None | None | N | None | 0 | 2.29053E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 18177 |
Fn3-20 |
12 | None | 0.1561 | None | 0.001 | N | 0.288 | 0.13 | 0.234412748748 | gnomAD-4.0.0 | 1.59478E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86467E-06 | 0 | 0 |
| D/N | 18283 |
Fn3-21 |
12 | None | 0.6525 | None | 1.0 | N | 0.628 | 0.344 | 0.40032279838 | gnomAD-4.0.0 | 7.03831E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.7019E-05 |
| D/Y | 18283 |
Fn3-21 |
12 | None | 0.87 | None | 1.0 | N | 0.621 | 0.498 | 0.65934590787 | gnomAD-4.0.0 | 2.11149E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.75066E-06 | 0 | 0 |
| D/E | 18490 |
Fn3-22 |
12 | None | 0.3499 | None | 0.067 | N | 0.247 | 0.089 | 0.119812018005 | gnomAD-4.0.0 | 1.59384E-06 | None | None | None | None | N | None | 0 | 2.28791E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/I | 18590 |
Fn3-23 |
12 | None | 0.0993 | None | 0.999 | N | 0.438 | 0.187 | 0.376921832658 | gnomAD-4.0.0 | 3.51893E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.17959E-06 | 0 | 0 |
| S/C | 18895 |
Fn3-25 |
12 | rs1289916968 |
0.1711 | -0.077 | 0.999 | N | 0.437 | 0.293 | 0.385417323374 | gnomAD-2.1.1 | 1.31E-05 | None | None | None | None | N | None | 6.71E-05 | 6.58E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/C | 18895 |
Fn3-25 |
12 | rs1289916968 |
0.1711 | -0.077 | 0.999 | N | 0.437 | 0.293 | 0.385417323374 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 1.31079E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 18895 |
Fn3-25 |
12 | rs1289916968 |
0.1711 | -0.077 | 0.999 | N | 0.437 | 0.293 | 0.385417323374 | gnomAD-4.0.0 | 6.29312E-06 | None | None | None | None | N | None | 8.1226E-05 | 7.10152E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 18895 |
Fn3-25 |
12 | rs1289916968 |
0.1256 | -0.565 | 0.826 | N | 0.344 | 0.098 | 0.257786959452 | gnomAD-2.1.1 | 4.36E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.49E-06 | 0 |
| S/G | 18895 |
Fn3-25 |
12 | rs1289916968 |
0.1256 | -0.565 | 0.826 | N | 0.344 | 0.098 | 0.257786959452 | gnomAD-4.0.0 | 1.39178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.8194E-06 | 0 | 0 |
| S/I | 18895 |
Fn3-25 |
12 | rs2052561080 |
0.424 | None | 0.996 | N | 0.492 | 0.347 | 0.496560916508 | gnomAD-4.0.0 | 1.65177E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.95688E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 18895 |
Fn3-25 |
12 | rs375403059 |
0.8926 | 0.044 | 0.99 | N | 0.43 | 0.239 | 0.357519025918 | gnomAD-2.1.1 | 4.33E-06 | None | None | None | None | N | None | 0 | 3.24E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/R | 18895 |
Fn3-25 |
12 | rs375403059 |
0.8926 | 0.044 | 0.99 | N | 0.43 | 0.239 | 0.357519025918 | gnomAD-4.0.0 | 6.95199E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.09243E-07 | 0 | 0 |
| D/H | 18999 |
Fn3-26 |
12 | rs2052422100 |
0.945 | None | 1.0 | N | 0.643 | 0.481 | 0.415438038341 | gnomAD-4.0.0 | 6.88008E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0105E-07 | 0 | 0 |
| N/H | 19195 |
Fn3-27 |
13 | rs757544346 |
0.1261 | -0.903 | 1.0 | N | 0.665 | 0.435 | 0.318540980066 | gnomAD-2.1.1 | 4.18E-06 | None | None | None | None | N | None | 6.75E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/H | 19195 |
Fn3-27 |
13 | rs757544346 |
0.1261 | -0.903 | 1.0 | N | 0.665 | 0.435 | 0.318540980066 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 19195 |
Fn3-27 |
13 | rs757544346 |
0.1261 | -0.903 | 1.0 | N | 0.665 | 0.435 | 0.318540980066 | gnomAD-4.0.0 | 2.58081E-06 | None | None | None | None | N | None | 3.38765E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 19195 |
Fn3-27 |
13 | rs754292868 |
0.1 | -0.357 | 0.999 | N | 0.484 | 0.352 | 0.267755039894 | gnomAD-2.1.1 | 8.35E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.82E-05 | None | 0 | None | 0 | 9.23E-06 | 0 |
| N/S | 19195 |
Fn3-27 |
13 | rs754292868 |
0.1 | -0.357 | 0.999 | N | 0.484 | 0.352 | 0.267755039894 | gnomAD-4.0.0 | 4.1206E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.54414E-05 | None | 0 | 0 | 3.60554E-06 | 1.17908E-05 | 0 |
| E/V | 19491 |
Fn3-29 |
13 | rs2050771375 |
0.3994 | None | 1.0 | N | 0.7 | 0.603 | 0.556695477184 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| E/V | 19491 |
Fn3-29 |
13 | rs2050771375 |
0.3994 | None | 1.0 | N | 0.7 | 0.603 | 0.556695477184 | gnomAD-4.0.0 | 6.57851E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| E/A | 19590 |
Fn3-30 |
12 | rs2050672836 |
0.215 | None | 0.026 | N | 0.263 | 0.19 | 0.298056030225 | gnomAD-4.0.0 | 1.59332E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85995E-06 | 0 | 0 |
| E/Q | 19590 |
Fn3-30 |
12 | None | 0.2411 | None | 0.984 | D | 0.553 | 0.255 | 0.424073947737 | gnomAD-4.0.0 | 1.59333E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4381E-05 | 0 |
| D/E | 19691 |
Fn3-31 |
12 | None | 0.6317 | None | 0.963 | N | 0.431 | 0.275 | 0.307016933798 | gnomAD-4.0.0 | 1.36873E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79918E-06 | 0 | 0 |
| E/A | 19888 |
Fn3-32 |
12 | rs564006895 |
0.49 | -0.89 | 0.896 | D | 0.558 | 0.403 | 0.365509141856 | gnomAD-2.1.1 | 1.64E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.83E-05 | 3.37268E-04 |
| E/A | 19888 |
Fn3-32 |
12 | rs564006895 |
0.49 | -0.89 | 0.896 | D | 0.558 | 0.403 | 0.365509141856 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/A | 19888 |
Fn3-32 |
12 | rs564006895 |
0.49 | -0.89 | 0.896 | D | 0.558 | 0.403 | 0.365509141856 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/A | 19888 |
Fn3-32 |
12 | rs564006895 |
0.49 | -0.89 | 0.896 | D | 0.558 | 0.403 | 0.365509141856 | gnomAD-4.0.0 | 1.42704E-05 | None | None | None | None | N | None | 0 | 1.6733E-05 | None | 0 | 0 | None | 1.56647E-05 | 0 | 1.78131E-05 | 0 | 0 |
| E/K | 19888 |
Fn3-32 |
12 | rs369279578 |
0.603 | 0.227 | 0.896 | N | 0.533 | 0.345 | None | gnomAD-2.1.1 | 1.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.31E-05 | None | 0 | 1.83E-05 | 0 |
| E/K | 19888 |
Fn3-32 |
12 | rs369279578 |
0.603 | 0.227 | 0.896 | N | 0.533 | 0.345 | None | gnomAD-4.0.0 | 6.85213E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.10174E-06 | 1.16344E-05 | 0 |
| D/V | 19988 |
Fn3-33 |
12 | None | 0.6406 | None | 1.0 | N | 0.711 | 0.546 | 0.461759001683 | gnomAD-4.0.0 | 3.18477E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88267E-05 | 0 | 0 | 0 | 3.02627E-05 |
| D/G | 20183 |
Fn3-34 |
13 | None | 0.2345 | None | 0.117 | N | 0.379 | 0.244 | 0.218845423259 | gnomAD-4.0.0 | 1.5921E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| D/E | 20282 |
Fn3-35 |
12 | None | 0.242 | None | 1.0 | N | 0.387 | 0.307 | 0.19670166235 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/E | 20382 |
Fn3-36 |
12 | None | 0.7998 | None | 1.0 | N | 0.389 | 0.245 | 0.316788114976 | gnomAD-4.0.0 | 1.5941E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77855E-05 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 20580 |
Fn3-37 |
12 | rs2049862820 |
0.1315 | None | 0.001 | N | 0.085 | 0.121 | 0.165133752707 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 20580 |
Fn3-37 |
12 | rs2049862820 |
0.1315 | None | 0.001 | N | 0.085 | 0.121 | 0.165133752707 | gnomAD-4.0.0 | 6.57523E-06 | None | None | None | None | N | None | 2.41255E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 20580 |
Fn3-37 |
12 | rs1470758075 |
0.0853 | 0.232 | None | N | 0.045 | 0.119 | 0.117506650769 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.63E-05 | None | 3.27E-05 | None | 0 | 0 | 0 |
| N/S | 20580 |
Fn3-37 |
12 | rs1470758075 |
0.0853 | 0.232 | None | N | 0.045 | 0.119 | 0.117506650769 | gnomAD-4.0.0 | 1.36893E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99664E-07 | 1.15964E-05 | 0 |
| D/E | 20679 |
Fn3-38 |
12 | rs878956804 |
0.3287 | -0.105 | 0.002 | N | 0.176 | 0.085 | 0.12205267543 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| D/E | 20679 |
Fn3-38 |
12 | rs878956804 |
0.3287 | -0.105 | 0.002 | N | 0.176 | 0.085 | 0.12205267543 | gnomAD-4.0.0 | 4.10583E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52131E-05 | None | 0 | 0 | 3.59831E-06 | 0 | 1.65673E-05 |
| D/Y | 20679 |
Fn3-38 |
12 | None | 0.8223 | None | 0.975 | N | 0.629 | 0.438 | 0.698802292485 | gnomAD-4.0.0 | 4.77537E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.55155E-05 | None | 0 | 0 | 2.85938E-06 | 0 | 0 |
| K/E | 20974 |
Fn3-40 |
12 | rs370100134 |
0.5025 | 0.266 | 0.977 | N | 0.54 | 0.244 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| K/E | 20974 |
Fn3-40 |
12 | rs370100134 |
0.5025 | 0.266 | 0.977 | N | 0.54 | 0.244 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/E | 20974 |
Fn3-40 |
12 | rs370100134 |
0.5025 | 0.266 | 0.977 | N | 0.54 | 0.244 | None | gnomAD-4.0.0 | 8.67813E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.10209E-05 | 0 | 1.60149E-05 |
| K/N | 20974 |
Fn3-40 |
12 | None | 0.6986 | None | 0.993 | N | 0.673 | 0.162 | 0.206339911435 | gnomAD-4.0.0 | 1.59222E-06 | None | None | None | None | N | None | 0 | 2.28822E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 21277 |
Fn3-42 |
12 | rs2049253649 |
0.0909 | None | 0.884 | N | 0.271 | 0.286 | 0.237489013734 | gnomAD-4.0.0 | 4.79721E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.01605E-04 | None | 0 | 0 | 2.70101E-06 | 0 | 0 |
| D/N | 21571 |
Fn3-44 |
13 | rs750771623 |
0.1171 | 0.596 | 0.22 | N | 0.505 | 0.198 | 0.198526703765 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| D/N | 21571 |
Fn3-44 |
13 | rs750771623 |
0.1171 | 0.596 | 0.22 | N | 0.505 | 0.198 | 0.198526703765 | gnomAD-4.0.0 | 4.77737E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.5802E-06 | 0 | 0 |
| K/R | 21670 |
Fn3-45 |
12 | rs1380994472 |
0.0787 | -0.078 | 0.958 | N | 0.483 | 0.234 | 0.347879110917 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14837E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/R | 21670 |
Fn3-45 |
12 | rs1380994472 |
0.0787 | -0.078 | 0.958 | N | 0.483 | 0.234 | 0.347879110917 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 21670 |
Fn3-45 |
12 | rs1380994472 |
0.0787 | -0.078 | 0.958 | N | 0.483 | 0.234 | 0.347879110917 | gnomAD-4.0.0 | 3.84819E-06 | None | None | None | None | N | None | 5.07803E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/A | 21768 |
Fn3-46 |
12 | rs1171277318 |
0.4612 | -0.383 | 1.0 | N | 0.72 | 0.476 | 0.418344901717 | gnomAD-2.1.1 | 4.38E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.94E-05 | None | 0 | None | 0 | 0 | 0 |
| D/A | 21768 |
Fn3-46 |
12 | rs1171277318 |
0.4612 | -0.383 | 1.0 | N | 0.72 | 0.476 | 0.418344901717 | gnomAD-4.0.0 | 1.64911E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.83238E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 21768 |
Fn3-46 |
12 | rs896934140 |
0.6709 | None | 1.0 | N | 0.639 | 0.442 | 0.415564226483 | gnomAD-4.0.0 | 1.38996E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.82215E-06 | 0 | 0 |
| D/N | 21768 |
Fn3-46 |
12 | None | 0.2439 | None | 1.0 | N | 0.655 | 0.361 | 0.340510301474 | gnomAD-4.0.0 | 6.94979E-07 | None | None | None | None | N | None | 0 | 0 | None | 3.90656E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 21768 |
Fn3-46 |
12 | None | 0.6376 | None | 1.0 | N | 0.646 | 0.454 | 0.688919053348 | gnomAD-4.0.0 | 6.94981E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.11079E-07 | 0 | 0 |
| K/E | 21967 |
Fn3-47 |
12 | None | 0.2803 | None | 0.09 | N | 0.381 | 0.073 | 0.16115917748 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| K/N | 21967 |
Fn3-47 |
12 | None | 0.4476 | None | 0.001 | N | 0.109 | 0.073 | 0.115124310173 | gnomAD-4.0.0 | 8.40225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.18751E-06 | 0 | 0 |
| N/D | 22066 |
Fn3-48 |
12 | rs1394300458 |
0.3734 | 0.339 | 0.958 | N | 0.477 | 0.352 | 0.180583059064 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| N/D | 22066 |
Fn3-48 |
12 | rs1394300458 |
0.3734 | 0.339 | 0.958 | N | 0.477 | 0.352 | 0.180583059064 | gnomAD-4.0.0 | 8.21548E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.89661E-06 | 0 | 1.65744E-05 |
| N/S | 22066 |
Fn3-48 |
12 | rs1400000859 |
0.1054 | 0.15 | 0.958 | N | 0.407 | 0.312 | 0.151104730317 | gnomAD-2.1.1 | 7.19E-06 | None | None | None | None | N | None | 4.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.89E-06 | 0 |
| N/S | 22066 |
Fn3-48 |
12 | rs1400000859 |
0.1054 | 0.15 | 0.958 | N | 0.407 | 0.312 | 0.151104730317 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/S | 22066 |
Fn3-48 |
12 | rs1400000859 |
0.1054 | 0.15 | 0.958 | N | 0.407 | 0.312 | 0.151104730317 | gnomAD-4.0.0 | 1.97291E-05 | None | None | None | None | N | None | 4.82532E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47089E-05 | 0 | 0 |
| D/H | 22167 |
Fn3-49 |
12 | rs2047803841 |
0.9631 | None | 1.0 | N | 0.643 | 0.46 | 0.340032825777 | gnomAD-4.0.0 | 6.8919E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.17647E-05 | 0 |
| D/N | 22167 |
Fn3-49 |
12 | None | 0.6587 | None | 1.0 | N | 0.638 | 0.381 | 0.278968121808 | gnomAD-4.0.0 | 1.37838E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.03904E-07 | 0 | 1.669E-05 |
| E/A | 22365 |
Fn3-50 |
12 | rs1449941116 |
0.4023 | -0.903 | 0.581 | N | 0.571 | 0.366 | 0.458554320643 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| D/H | 22754 |
Fn3-53 |
12 | None | 0.2322 | None | 0.295 | N | 0.394 | 0.215 | 0.245101548738 | gnomAD-4.0.0 | 6.85119E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16673E-05 | 0 |
| D/N | 22754 |
Fn3-53 |
12 | rs755823330 |
0.1137 | 0.079 | 0.024 | N | 0.215 | 0.175 | 0.167679373172 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| D/N | 22754 |
Fn3-53 |
12 | rs755823330 |
0.1137 | 0.079 | 0.024 | N | 0.215 | 0.175 | 0.167679373172 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| D/N | 22754 |
Fn3-53 |
12 | rs755823330 |
0.1137 | 0.079 | 0.024 | N | 0.215 | 0.175 | 0.167679373172 | gnomAD-4.0.0 | 1.36515E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.86599E-05 | 0 | 0 |
| N/K | 22852 |
Fn3-54 |
12 | rs780727295 |
0.4578 | 0.604 | 0.124 | N | 0.586 | 0.105 | 0.0954503805726 | gnomAD-2.1.1 | 1.74E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.30229E-04 | None | 0 | None | 0 | 0 | 0 |
| N/K | 22852 |
Fn3-54 |
12 | rs780727295 |
0.4578 | 0.604 | 0.124 | N | 0.586 | 0.105 | 0.0954503805726 | gnomAD-4.0.0 | 3.3017E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.60538E-05 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 23051 |
Fn3-55 |
12 | None | 0.1018 | None | 0.97 | N | 0.565 | 0.286 | 0.19670166235 | gnomAD-4.0.0 | 1.59281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78676E-05 | None | 0 | 0 | 0 | 0 | 0 |
| N/T | 23051 |
Fn3-55 |
12 | None | 0.135 | None | 0.698 | N | 0.549 | 0.122 | 0.265010934533 | gnomAD-4.0.0 | 3.1856E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41779E-04 | 2.86061E-06 | 0 | 0 |
| D/N | 23251 |
Fn3-57 |
12 | None | 0.622 | None | 0.999 | D | 0.665 | 0.385 | 0.272205846399 | gnomAD-4.0.0 | 3.47087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.80647E-05 | None | 0 | 0 | 3.01819E-06 | 0 | 0 |
| D/Y | 23251 |
Fn3-57 |
12 | None | 0.9214 | None | 1.0 | N | 0.745 | 0.485 | 0.658222036576 | gnomAD-4.0.0 | 1.73544E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.01819E-06 | 0 | 0 |
| D/A | 23446 |
Fn3-58 |
12 | None | 0.1107 | None | 0.338 | N | 0.464 | 0.311 | 0.344945010812 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 23446 |
Fn3-58 |
12 | rs1290459779 |
0.0883 | 0.399 | 0.505 | N | 0.443 | 0.218 | 0.193865811164 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.96E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 23446 |
Fn3-58 |
12 | rs1290459779 |
0.0883 | 0.399 | 0.505 | N | 0.443 | 0.218 | 0.193865811164 | gnomAD-4.0.0 | 1.59285E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76872E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 23543 |
Fn3-59 |
12 | rs376809423 |
0.5686 | 0.024 | 0.994 | N | 0.388 | 0.271 | 0.193865811164 | gnomAD-4.0.0 | 3.42122E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49769E-06 | 0 | 0 |
| D/N | 23543 |
Fn3-59 |
12 | None | 0.4303 | None | 1.0 | N | 0.613 | 0.329 | 0.241664281697 | gnomAD-4.0.0 | 1.59149E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77269E-05 | None | 0 | 0 | 0 | 0 | 0 |
| E/A | 24134 |
Fn3-63 |
13 | None | 0.1567 | None | 0.027 | N | 0.369 | 0.219 | 0.266385636622 | gnomAD-4.0.0 | 1.7459E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.68481E-05 | 0 |
| T/A | 24233 |
Fn3-64 |
12 | None | 0.0503 | None | None | N | 0.063 | 0.183 | 0.0138822411134 | gnomAD-4.0.0 | 7.31964E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.35916E-07 | 0 | 0 |
| T/S | 24233 |
Fn3-64 |
12 | rs768359972 |
0.0857 | -0.393 | None | N | 0.055 | 0.162 | 0.0666544352282 | gnomAD-2.1.1 | 1.14E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.39509E-04 | None | 0 | 0 | 0 |
| T/S | 24233 |
Fn3-64 |
12 | rs768359972 |
0.0857 | -0.393 | None | N | 0.055 | 0.162 | 0.0666544352282 | gnomAD-4.0.0 | 3.75315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.87087E-05 | 0 |
| D/Y | 24334 |
Fn3-65 |
12 | None | 0.926 | None | 0.999 | N | 0.691 | 0.456 | 0.601252736945 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| E/A | 24530 |
Fn3-66 |
12 | None | 0.2646 | None | 0.859 | N | 0.554 | 0.293 | 0.424549175451 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/D | 24530 |
Fn3-66 |
12 | None | 0.0863 | None | 0.14 | N | 0.403 | 0.033 | 0.112648838833 | gnomAD-4.0.0 | 6.84351E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99593E-07 | 0 | 0 |
| E/K | 24530 |
Fn3-66 |
12 | None | 0.5428 | None | 0.919 | N | 0.477 | 0.267 | 0.369867359543 | gnomAD-4.0.0 | 1.36869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99585E-07 | 1.15955E-05 | 0 |
| D/G | 24627 |
Fn3-67 |
12 | None | 0.7156 | None | 0.93 | N | 0.59 | 0.454 | 0.298056030225 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/Q | 24820 |
Fn3-68 |
13 | None | 0.2912 | None | 0.983 | N | 0.58 | 0.284 | 0.338834610459 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 24919 |
Fn3-69 |
12 | None | 0.0512 | None | 0.004 | N | 0.163 | 0.067 | 0.199424873507 | gnomAD-4.0.0 | 3.60099E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.93753E-06 | 0 | 0 |
| I/T | 25017 |
Fn3-70 |
12 | rs771941844 |
0.1171 | -0.53 | 0.939 | N | 0.598 | 0.126 | 0.619116397592 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/T | 25017 |
Fn3-70 |
12 | rs771941844 |
0.1171 | -0.53 | 0.939 | N | 0.598 | 0.126 | 0.619116397592 | gnomAD-4.0.0 | 4.79114E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49871E-06 | 2.31932E-05 | 0 |
| G/E | 25216 |
Fn3-71 |
13 | None | 0.3692 | None | 1.0 | N | 0.66 | 0.485 | 0.510758216515 | gnomAD-4.0.0 | 6.84405E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99591E-07 | 0 | 0 |
| G/V | 25216 |
Fn3-71 |
13 | rs748480491 |
0.3397 | 0.074 | 1.0 | N | 0.661 | 0.478 | 0.642121336873 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| G/V | 25216 |
Fn3-71 |
13 | rs748480491 |
0.3397 | 0.074 | 1.0 | N | 0.661 | 0.478 | 0.642121336873 | gnomAD-4.0.0 | 1.71101E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.24898E-05 | 0 | 0 |
| D/E | 25416 |
Fn3-73 |
12 | rs781781445 |
0.659 | 0.063 | 0.978 | N | 0.419 | 0.303 | 0.225902525712 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| D/E | 25416 |
Fn3-73 |
12 | rs781781445 |
0.659 | 0.063 | 0.978 | N | 0.419 | 0.303 | 0.225902525712 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| D/E | 25416 |
Fn3-73 |
12 | rs781781445 |
0.659 | 0.063 | 0.978 | N | 0.419 | 0.303 | 0.225902525712 | gnomAD-4.0.0 | 4.95884E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93412E-06 | 0 | 1.60174E-05 |
| E/D | 25612 |
Fn3-74 |
12 | rs1707240113 |
0.0756 | None | None | N | 0.133 | 0.118 | 0.115124310173 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/A | 25709 |
Fn3-75 |
12 | rs1707103269 |
0.5426 | None | 1.0 | N | 0.735 | 0.556 | 0.467247493403 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88184E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/A | 25709 |
Fn3-75 |
12 | rs1707103269 |
0.5426 | None | 1.0 | N | 0.735 | 0.556 | 0.467247493403 | gnomAD-4.0.0 | 6.57549E-06 | None | None | None | None | N | None | 0 | 0 | None | 2.88184E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 25709 |
Fn3-75 |
12 | rs772757849 |
0.741 | -0.418 | 1.0 | N | 0.666 | 0.517 | 0.360565625551 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.13E-05 | 0 |
| D/H | 25709 |
Fn3-75 |
12 | rs772757849 |
0.741 | -0.418 | 1.0 | N | 0.666 | 0.517 | 0.360565625551 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/H | 25709 |
Fn3-75 |
12 | rs772757849 |
0.741 | -0.418 | 1.0 | N | 0.666 | 0.517 | 0.360565625551 | gnomAD-4.0.0 | 8.67806E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18689E-05 | 0 | 0 |
| D/V | 25709 |
Fn3-75 |
12 | rs1707103269 |
0.6917 | None | 1.0 | N | 0.773 | 0.645 | 0.690481662768 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/V | 25709 |
Fn3-75 |
12 | rs1707103269 |
0.6917 | None | 1.0 | N | 0.773 | 0.645 | 0.690481662768 | gnomAD-4.0.0 | 6.57549E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47119E-05 | 0 | 0 |
| D/Y | 25709 |
Fn3-75 |
12 | rs772757849 |
0.7033 | -0.085 | 1.0 | N | 0.698 | 0.526 | 0.723653669168 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| D/E | 25902 |
Fn3-76 |
13 | None | 0.0731 | None | 0.002 | N | 0.171 | 0.055 | 0.0666544352282 | gnomAD-4.0.0 | 2.05335E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69889E-06 | 0 | 0 |
| D/N | 25902 |
Fn3-76 |
13 | None | 0.0918 | None | 0.334 | N | 0.487 | 0.221 | 0.27855597813 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 1.94099E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 25902 |
Fn3-76 |
13 | None | 0.1559 | None | 0.638 | N | 0.653 | 0.402 | 0.477685322099 | gnomAD-4.0.0 | 1.59245E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85981E-06 | 0 | 0 |
| A/V | 26001 |
Fn3-77 |
12 | rs774218394 |
0.088 | 0.123 | None | N | 0.095 | 0.131 | 0.287603790349 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| M/L | 26099 |
Fn3-78 |
12 | rs374376033 |
0.0872 | None | None | N | 0.043 | 0.104 | 0.420570264827 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/L | 26099 |
Fn3-78 |
12 | rs374376033 |
0.0872 | None | None | N | 0.043 | 0.104 | 0.420570264827 | gnomAD-4.0.0 | 6.57514E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47076E-05 | 0 | 0 |
| M/R | 26099 |
Fn3-78 |
12 | rs1346797877 |
0.1454 | 1.189 | 0.065 | N | 0.397 | 0.223 | 0.488477830397 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| M/R | 26099 |
Fn3-78 |
12 | rs1346797877 |
0.1454 | 1.189 | 0.065 | N | 0.397 | 0.223 | 0.488477830397 | gnomAD-4.0.0 | 2.05294E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69875E-06 | 0 | 0 |
| M/T | 26099 |
Fn3-78 |
12 | None | 0.0905 | None | 0.014 | N | 0.247 | 0.208 | 0.658753162807 | gnomAD-4.0.0 | 5.4745E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29708E-06 | 0 | 1.65695E-05 |
| M/V | 26099 |
Fn3-78 |
12 | rs374376033 |
0.0569 | 0.381 | None | N | 0.021 | 0.122 | None | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 1.24018E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/V | 26099 |
Fn3-78 |
12 | rs374376033 |
0.0569 | 0.381 | None | N | 0.021 | 0.122 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 1.68927E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/V | 26099 |
Fn3-78 |
12 | rs374376033 |
0.0569 | 0.381 | None | N | 0.021 | 0.122 | None | gnomAD-4.0.0 | 7.43761E-06 | None | None | None | None | N | None | 1.60248E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 26298 |
Fn3-79 |
13 | rs72648205 |
0.6969 | 0.006 | 0.983 | N | 0.635 | 0.316 | 0.566774491594 | gnomAD-2.1.1 | 3.48857E-04 | None | None | None | None | N | None | 8.29E-05 | 1.14797E-04 | None | 2.52934E-03 | 0 | None | 0 | None | 0 | 4.68537E-04 | 8.64553E-04 |
| G/R | 26298 |
Fn3-79 |
13 | rs72648205 |
0.6969 | 0.006 | 0.983 | N | 0.635 | 0.316 | 0.566774491594 | gnomAD-3.1.2 | 3.48528E-04 | None | None | None | None | N | None | 7.24E-05 | 2.62295E-04 | 0 | 3.45622E-03 | 0 | None | 0 | 0 | 5.00059E-04 | 0 | 0 |
| G/R | 26298 |
Fn3-79 |
13 | rs72648205 |
0.6969 | 0.006 | 0.983 | N | 0.635 | 0.316 | 0.566774491594 | gnomAD-4.0.0 | 2.91069E-04 | None | None | None | None | N | None | 5.36322E-05 | 1.85048E-04 | None | 2.49249E-03 | 0 | None | 3.13804E-05 | 0 | 2.99126E-04 | 0 | 4.18437E-04 |
| N/D | 26397 |
Fn3-80 |
12 | rs1349397397 |
0.4383 | None | 0.958 | N | 0.434 | 0.399 | 0.256283259241 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/H | 26498 |
Fn3-81 |
12 | rs1705981523 |
0.9511 | None | 1.0 | N | 0.621 | 0.538 | 0.356484672536 | gnomAD-4.0.0 | 1.36926E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79907E-06 | 0 | 0 |
| D/E | 26791 |
Fn3-83 |
12 | rs749401230 |
0.4958 | 0.315 | 0.047 | N | 0.216 | 0.128 | 0.17258766438 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 1.24008E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 26791 |
Fn3-83 |
12 | rs749401230 |
0.4958 | 0.315 | 0.047 | N | 0.216 | 0.128 | 0.17258766438 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20651E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 26791 |
Fn3-83 |
12 | rs749401230 |
0.4958 | 0.315 | 0.047 | N | 0.216 | 0.128 | 0.17258766438 | gnomAD-4.0.0 | 4.33841E-06 | None | None | None | None | N | None | 9.34704E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/G | 26791 |
Fn3-83 |
12 | None | 0.5641 | None | 0.959 | N | 0.574 | 0.543 | 0.324161360171 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76872E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 26791 |
Fn3-83 |
12 | None | 0.7872 | None | 0.999 | N | 0.655 | 0.543 | 0.36036328697 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/P | 27083 |
Fn3-85 |
12 | rs186273940 |
0.8169 | 0.009 | 0.662 | N | 0.455 | 0.236 | None | gnomAD-2.1.1 | 2.58928E-04 | None | None | None | None | N | None | 8.28E-05 | 8.56E-05 | None | 0 | 0 | None | 0 | None | 0 | 5.27003E-04 | 0 |
| S/P | 27083 |
Fn3-85 |
12 | rs186273940 |
0.8169 | 0.009 | 0.662 | N | 0.455 | 0.236 | None | gnomAD-3.1.2 | 9.86012E-04 | None | None | None | None | N | None | 1.20662E-04 | 1.31027E-04 | 1.11842E-01 | 0 | 0 | None | 0 | 0 | 5.88201E-04 | 0 | 4.77555E-04 |
| S/P | 27083 |
Fn3-85 |
12 | rs186273940 |
0.8169 | 0.009 | 0.662 | N | 0.455 | 0.236 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 3E-03 | None | None | None | 0 | None |
| S/P | 27083 |
Fn3-85 |
12 | rs186273940 |
0.8169 | 0.009 | 0.662 | N | 0.455 | 0.236 | None | gnomAD-4.0.0 | 4.15515E-04 | None | None | None | None | N | None | 1.20147E-04 | 1.00331E-04 | None | 0 | 0 | None | 0 | 0 | 4.62104E-04 | 0 | 1.28213E-04 |
| V/A | 27181 |
Fn3-86 |
12 | rs750155984 |
0.1759 | -0.616 | 0.005 | N | 0.044 | 0.102 | 0.401327265625 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| A/P | 27480 |
Fn3-88 |
12 | rs1457913909 |
0.7551 | None | 0.939 | N | 0.407 | 0.231 | 0.250579442822 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/Y | 27581 |
Fn3-89 |
12 | rs1471458270 |
0.8165 | -0.06 | 1.0 | N | 0.667 | 0.426 | 0.659863245131 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| D/Y | 27581 |
Fn3-89 |
12 | rs1471458270 |
0.8165 | -0.06 | 1.0 | N | 0.667 | 0.426 | 0.659863245131 | gnomAD-4.0.0 | 1.36853E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.799E-06 | 0 | 0 |
| E/A | 27777 |
Fn3-90 |
12 | None | 0.2559 | None | 0.367 | N | 0.387 | 0.295 | 0.338110398507 | gnomAD-4.0.0 | 1.59268E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85981E-06 | 0 | 0 |
| D/E | 27874 |
Fn3-91 |
12 | rs771240950 |
0.6505 | 0.042 | 0.994 | N | 0.393 | 0.214 | 0.168933306366 | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| D/E | 27874 |
Fn3-91 |
12 | rs771240950 |
0.6505 | 0.042 | 0.994 | N | 0.393 | 0.214 | 0.168933306366 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/E | 27874 |
Fn3-91 |
12 | rs771240950 |
0.6505 | 0.042 | 0.994 | N | 0.393 | 0.214 | 0.168933306366 | gnomAD-4.0.0 | 6.82346E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32686E-06 | 0 | 0 |
| D/G | 27874 |
Fn3-91 |
12 | rs1377067134 |
0.7004 | None | 1.0 | N | 0.717 | 0.613 | 0.297031009988 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 27874 |
Fn3-91 |
12 | rs1377067134 |
0.7004 | None | 1.0 | N | 0.717 | 0.613 | 0.297031009988 | gnomAD-4.0.0 | 5.07499E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.02468E-06 | 0 | 0 |
| D/V | 27874 |
Fn3-91 |
12 | rs1377067134 |
0.875 | 0.344 | 1.0 | N | 0.743 | 0.614 | 0.692570320384 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| E/K | 28066 |
Fn3-92 |
12 | rs1703825463 |
0.2114 | None | 0.822 | N | 0.512 | 0.299 | 0.272205846399 | gnomAD-4.0.0 | 2.05312E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69873E-06 | 0 | 0 |
| H/D | 28165 |
Fn3-93 |
12 | rs1472903597 |
0.206 | -0.128 | 0.549 | N | 0.325 | 0.309 | 0.141422826196 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| H/D | 28165 |
Fn3-93 |
12 | rs1472903597 |
0.206 | -0.128 | 0.549 | N | 0.325 | 0.309 | 0.141422826196 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/D | 28165 |
Fn3-93 |
12 | rs1472903597 |
0.206 | -0.128 | 0.549 | N | 0.325 | 0.309 | 0.141422826196 | gnomAD-4.0.0 | 1.24146E-06 | None | None | None | None | N | None | 2.67308E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 28165 |
Fn3-93 |
12 | rs876658088 |
0.1181 | None | 0.379 | N | 0.217 | 0.161 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| H/R | 28165 |
Fn3-93 |
12 | rs876658088 |
0.1181 | None | 0.379 | N | 0.217 | 0.161 | None | gnomAD-4.0.0 | 1.42753E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.95149E-05 | 0 | 0 |
| N/D | 28263 |
Fn3-94 |
12 | rs762665595 |
0.1497 | 0.457 | 0.067 | N | 0.265 | 0.107 | 0.126345400529 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 7.32654E-05 |
| N/Y | 28263 |
Fn3-94 |
12 | rs762665595 |
0.2087 | -0.433 | 0.998 | N | 0.599 | 0.413 | 0.535152128566 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| S/C | 28561 |
Fn3-96 |
12 | rs781472455 |
0.1565 | -0.192 | 1.0 | D | 0.647 | 0.298 | None | gnomAD-2.1.1 | 4.29E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 3.20899E-04 | 2.35E-05 | 1.40924E-04 |
| S/C | 28561 |
Fn3-96 |
12 | rs781472455 |
0.1565 | -0.192 | 1.0 | D | 0.647 | 0.298 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 2.83126E-04 | 0 | 4.41E-05 | 0 | 0 |
| S/C | 28561 |
Fn3-96 |
12 | rs781472455 |
0.1565 | -0.192 | 1.0 | D | 0.647 | 0.298 | None | gnomAD-4.0.0 | 5.51093E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.0851E-04 | 0 | 3.58986E-05 | 0 | 5.69087E-05 |
| S/P | 28561 |
Fn3-96 |
12 | rs1703206822 |
0.9375 | None | 0.997 | N | 0.639 | 0.302 | 0.229924730088 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 28561 |
Fn3-96 |
12 | rs1703206822 |
0.9375 | None | 0.997 | N | 0.639 | 0.302 | 0.229924730088 | gnomAD-4.0.0 | 6.57462E-06 | None | None | None | None | N | None | 0 | 6.55308E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/A | 28662 |
Fn3-97 |
12 | None | 0.7054 | None | 1.0 | N | 0.717 | 0.491 | 0.491660673884 | gnomAD-4.0.0 | 1.59154E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| D/H | 28662 |
Fn3-97 |
12 | None | 0.7852 | None | 1.0 | N | 0.639 | 0.423 | 0.405700215632 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/V | 28662 |
Fn3-97 |
12 | rs1703115388 |
0.8467 | None | 1.0 | N | 0.749 | 0.573 | 0.694480664743 | gnomAD-4.0.0 | 1.59154E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85894E-06 | 0 | 0 |
| D/Y | 28662 |
Fn3-97 |
12 | None | 0.7029 | None | 1.0 | N | 0.672 | 0.399 | 0.689839040572 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/E | 28856 |
Fn3-98 |
12 | None | 0.087 | None | 0.001 | N | 0.195 | 0.155 | 0.146414634003 | gnomAD-4.0.0 | 2.05264E-06 | None | None | None | None | N | None | 0 | 4.47187E-05 | None | 0 | 0 | None | 0 | 0 | 8.99483E-07 | 0 | 0 |
| D/H | 28856 |
Fn3-98 |
12 | rs747235124 |
0.2052 | 0.222 | 0.931 | N | 0.613 | 0.382 | 0.353125101423 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| D/H | 28856 |
Fn3-98 |
12 | rs747235124 |
0.2052 | 0.222 | 0.931 | N | 0.613 | 0.382 | 0.353125101423 | gnomAD-4.0.0 | 1.59132E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85845E-06 | 0 | 0 |
| S/G | 28953 |
Fn3-99 |
12 | rs748750008 |
0.0636 | -0.594 | None | N | 0.055 | 0.062 | 0.185906805712 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 8.78E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/G | 28953 |
Fn3-99 |
12 | rs748750008 |
0.0636 | -0.594 | None | N | 0.055 | 0.062 | 0.185906805712 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 28953 |
Fn3-99 |
12 | rs748750008 |
0.0636 | -0.594 | None | N | 0.055 | 0.062 | 0.185906805712 | gnomAD-4.0.0 | 3.84841E-06 | None | None | None | None | N | None | 0 | 5.09909E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 28953 |
Fn3-99 |
12 | rs1183912804 |
0.0716 | None | None | N | 0.045 | 0.062 | 0.171388866994 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| S/R | 28953 |
Fn3-99 |
12 | rs748750008 |
0.3046 | 0.139 | 0.055 | N | 0.45 | 0.122 | 0.231873229951 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.32E-05 | None | 0 | 0 | 0 |
| S/R | 28953 |
Fn3-99 |
12 | rs748750008 |
0.3046 | 0.139 | 0.055 | N | 0.45 | 0.122 | 0.231873229951 | gnomAD-4.0.0 | 3.18808E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85987E-06 | 1.44317E-05 | 0 |
| D/N | 29149 |
Fn3-100 |
13 | rs758707099 |
0.1053 | 0.322 | 0.235 | N | 0.271 | 0.125 | 0.212008924253 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| D/N | 29149 |
Fn3-100 |
13 | rs758707099 |
0.1053 | 0.322 | 0.235 | N | 0.271 | 0.125 | 0.212008924253 | gnomAD-4.0.0 | 3.42187E-06 | None | None | None | None | I | None | 0 | 2.23594E-05 | None | 0 | 0 | None | 0 | 1.7343E-04 | 8.99423E-07 | 0 | 3.31301E-05 |
| D/Y | 29149 |
Fn3-100 |
13 | rs758707099 |
0.4233 | 0.169 | 1.0 | N | 0.647 | 0.376 | 0.552615868945 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| D/Y | 29149 |
Fn3-100 |
13 | rs758707099 |
0.4233 | 0.169 | 1.0 | N | 0.647 | 0.376 | 0.552615868945 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/Y | 29149 |
Fn3-100 |
13 | rs758707099 |
0.4233 | 0.169 | 1.0 | N | 0.647 | 0.376 | 0.552615868945 | gnomAD-4.0.0 | 3.09916E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23781E-06 | 0 | 0 |
| D/A | 29346 |
Fn3-102 |
12 | None | 0.2853 | -0.133 | 0.993 | N | 0.673 | 0.531 | 0.418467456957 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/A | 29346 |
Fn3-102 |
12 | None | 0.2853 | -0.133 | 0.993 | N | 0.673 | 0.531 | 0.418467456957 | gnomAD-4.0.0 | 2.73718E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69846E-06 | 1.15977E-05 | 0 |
| D/G | 29346 |
Fn3-102 |
12 | rs374741129 |
0.2645 | None | 0.989 | N | 0.705 | 0.504 | 0.260249123532 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 29346 |
Fn3-102 |
12 | rs374741129 |
0.2645 | None | 0.989 | N | 0.705 | 0.504 | 0.260249123532 | gnomAD-4.0.0 | 6.56953E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47003E-05 | 0 | 0 |
| D/V | 29346 |
Fn3-102 |
12 | rs374741129 |
0.501 | 0.294 | 0.997 | N | 0.759 | 0.467 | None | gnomAD-2.1.1 | 4.04E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-05 | 0 |
| D/V | 29346 |
Fn3-102 |
12 | rs374741129 |
0.501 | 0.294 | 0.997 | N | 0.759 | 0.467 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/V | 29346 |
Fn3-102 |
12 | rs374741129 |
0.501 | 0.294 | 0.997 | N | 0.759 | 0.467 | None | gnomAD-4.0.0 | 2.41699E-05 | None | None | None | None | N | None | 1.33433E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.22096E-05 | 0 | 0 |
| T/I | 29545 |
Fn3-103 |
13 | rs1302609593 |
0.3188 | 0.15 | 0.988 | N | 0.424 | 0.297 | 0.3349148499 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| T/I | 29545 |
Fn3-103 |
13 | rs1302609593 |
0.3188 | 0.15 | 0.988 | N | 0.424 | 0.297 | 0.3349148499 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 29545 |
Fn3-103 |
13 | rs1302609593 |
0.3188 | 0.15 | 0.988 | N | 0.424 | 0.297 | 0.3349148499 | gnomAD-4.0.0 | 2.56187E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.42377E-05 | None | 0 | 0 | 2.39263E-06 | 0 | 0 |
| K/R | 29644 |
Fn3-104 |
12 | None | 0.0885 | None | 0.27 | N | 0.243 | 0.059 | 0.201204373187 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/E | 29745 |
Fn3-105 |
12 | None | 0.843 | None | 1.0 | N | 0.382 | 0.261 | 0.216624796971 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/H | 29745 |
Fn3-105 |
12 | None | 0.9504 | None | 1.0 | N | 0.641 | 0.439 | 0.356897458496 | gnomAD-4.0.0 | 1.61087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89677E-06 | 0 | 0 |
| H/Y | 29944 |
Fn3-106 |
12 | rs560541272 |
0.0927 | 1.302 | 0.961 | N | 0.38 | 0.181 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.56E-05 | 0 |
| H/Y | 29944 |
Fn3-106 |
12 | rs560541272 |
0.0927 | 1.302 | 0.961 | N | 0.38 | 0.181 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.78011E-04 |
| H/Y | 29944 |
Fn3-106 |
12 | rs560541272 |
0.0927 | 1.302 | 0.961 | N | 0.38 | 0.181 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| H/Y | 29944 |
Fn3-106 |
12 | rs560541272 |
0.0927 | 1.302 | 0.961 | N | 0.38 | 0.181 | None | gnomAD-4.0.0 | 1.05442E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18741E-05 | 0 | 4.804E-05 |
| D/G | 30041 |
Fn3-107 |
12 | None | 0.404 | None | 1.0 | N | 0.697 | 0.553 | 0.32714864917 | gnomAD-4.0.0 | 8.89428E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52003E-05 | None | 0 | 0 | 9.89381E-06 | 0 | 1.65645E-05 |
| D/N | 30041 |
Fn3-107 |
12 | rs1272355523 |
0.2091 | 0.161 | 1.0 | N | 0.636 | 0.362 | 0.299770980665 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 30041 |
Fn3-107 |
12 | rs1272355523 |
0.2091 | 0.161 | 1.0 | N | 0.636 | 0.362 | 0.299770980665 | gnomAD-4.0.0 | 1.36836E-06 | None | None | None | None | N | None | 0 | 2.23614E-05 | None | 0 | 2.52054E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 30041 |
Fn3-107 |
12 | rs1272355523 |
0.4578 | 0.077 | 1.0 | N | 0.619 | 0.481 | 0.711839974248 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/Y | 30041 |
Fn3-107 |
12 | rs1272355523 |
0.4578 | 0.077 | 1.0 | N | 0.619 | 0.481 | 0.711839974248 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| D/Y | 30041 |
Fn3-107 |
12 | rs1272355523 |
0.4578 | 0.077 | 1.0 | N | 0.619 | 0.481 | 0.711839974248 | gnomAD-4.0.0 | 3.71795E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.58733E-05 | 0 |
| E/G | 30236 |
Fn3-108 |
13 | None | 0.5591 | None | 1.0 | N | 0.635 | 0.483 | 0.459100921832 | gnomAD-4.0.0 | 6.84276E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99509E-07 | 0 | 0 |
| E/K | 30236 |
Fn3-108 |
13 | rs974510652 |
0.5364 | -0.182 | 0.999 | N | 0.573 | 0.384 | 0.385578977469 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| E/K | 30236 |
Fn3-108 |
13 | rs974510652 |
0.5364 | -0.182 | 0.999 | N | 0.573 | 0.384 | 0.385578977469 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 30236 |
Fn3-108 |
13 | rs974510652 |
0.5364 | -0.182 | 0.999 | N | 0.573 | 0.384 | 0.385578977469 | gnomAD-4.0.0 | 3.844E-06 | None | None | None | None | N | None | 1.69113E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78648E-06 | 0 | 0 |
| N/D | 30335 |
Fn3-109 |
12 | rs1199061926 |
0.3136 | 0.611 | 0.999 | N | 0.561 | 0.38 | 0.289098819767 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| N/D | 30335 |
Fn3-109 |
12 | rs1199061926 |
0.3136 | 0.611 | 0.999 | N | 0.561 | 0.38 | 0.289098819767 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| N/S | 30335 |
Fn3-109 |
12 | rs768793048 |
0.1012 | -0.108 | 0.999 | N | 0.524 | 0.429 | 0.278143212241 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 2.66E-05 | 0 |
| N/S | 30335 |
Fn3-109 |
12 | rs768793048 |
0.1012 | -0.108 | 0.999 | N | 0.524 | 0.429 | 0.278143212241 | gnomAD-4.0.0 | 6.84184E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09505E-06 | 0 | 1.65645E-05 |
| D/E | 30433 |
Fn3-110 |
12 | None | 0.6048 | None | 1.0 | N | 0.387 | 0.271 | 0.185906805712 | gnomAD-4.0.0 | 1.59269E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85971E-06 | 0 | 0 |
| N/I | 30631 |
Fn3-111 |
13 | None | 0.4311 | None | 0.949 | N | 0.667 | 0.267 | 0.40722173914 | gnomAD-4.0.0 | 1.38887E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.81867E-06 | 0 | 0 |
| N/S | 30631 |
Fn3-111 |
13 | rs755738504 |
0.0741 | -0.041 | 0.034 | N | 0.233 | 0.082 | 0.0762999501168 | gnomAD-2.1.1 | 4.23E-05 | None | None | None | None | N | None | 0 | 3.12E-05 | None | 0 | 1.70049E-04 | None | 7.3E-05 | None | 0 | 3.69E-05 | 0 |
| N/S | 30631 |
Fn3-111 |
13 | rs755738504 |
0.0741 | -0.041 | 0.034 | N | 0.233 | 0.082 | 0.0762999501168 | gnomAD-4.0.0 | 2.08331E-05 | None | None | None | None | N | None | 0 | 2.36351E-05 | None | 0 | 1.27078E-04 | None | 0 | 0 | 1.81867E-05 | 4.82125E-05 | 0 |
| D/A | 31124 |
Fn3-115 |
12 | rs775147653 |
0.6389 | -0.114 | 1.0 | N | 0.683 | 0.476 | 0.411799315854 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| D/A | 31124 |
Fn3-115 |
12 | rs775147653 |
0.6389 | -0.114 | 1.0 | N | 0.683 | 0.476 | 0.411799315854 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/A | 31124 |
Fn3-115 |
12 | rs775147653 |
0.6389 | -0.114 | 1.0 | N | 0.683 | 0.476 | 0.411799315854 | gnomAD-4.0.0 | 1.23937E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69519E-06 | 0 | 0 |
| D/V | 31124 |
Fn3-115 |
12 | rs775147653 |
0.813 | 0.266 | 1.0 | N | 0.707 | 0.559 | 0.414281671643 | gnomAD-2.1.1 | 1.24786E-04 | None | None | None | None | N | None | 0 | 8.9829E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/V | 31124 |
Fn3-115 |
12 | rs775147653 |
0.813 | 0.266 | 1.0 | N | 0.707 | 0.559 | 0.414281671643 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 31124 |
Fn3-115 |
12 | rs775147653 |
0.813 | 0.266 | 1.0 | N | 0.707 | 0.559 | 0.414281671643 | gnomAD-4.0.0 | 1.92102E-05 | None | None | None | None | N | None | 0 | 5.1677E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 31517 |
Fn3-118 |
12 | rs754507654 |
0.1528 | 0.334 | 0.884 | N | 0.27 | 0.232 | 0.219573609325 | gnomAD-2.1.1 | 4.26E-06 | None | None | None | None | N | None | 6.5E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 31517 |
Fn3-118 |
12 | rs754507654 |
0.1528 | 0.334 | 0.884 | N | 0.27 | 0.232 | 0.219573609325 | gnomAD-4.0.0 | 1.64601E-06 | None | None | None | None | N | None | 5.76768E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 31719 |
Fn3-119 |
12 | None | 0.152 | None | 0.997 | N | 0.538 | 0.307 | 0.29385284311 | gnomAD-4.0.0 | 1.5955E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86781E-06 | 0 | 0 |
| D/G | 31920 |
Fn3-121 |
12 | None | 0.7461 | None | 1.0 | N | 0.706 | 0.472 | 0.346768085243 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 32116 |
Fn3-122 |
12 | None | 0.2791 | None | 0.975 | N | 0.533 | 0.361 | 0.378498632473 | gnomAD-4.0.0 | 6.90551E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01367E-07 | 0 | 0 |
| D/N | 32213 |
Fn3-123 |
12 | rs764561909 |
0.2193 | 0.117 | 0.996 | N | 0.653 | 0.29 | None | gnomAD-2.1.1 | 3.21E-05 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 0 | 0 | None | 1.30719E-04 | None | 0 | 2.34E-05 | 0 |
| D/N | 32213 |
Fn3-123 |
12 | rs764561909 |
0.2193 | 0.117 | 0.996 | N | 0.653 | 0.29 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 9.66E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| D/N | 32213 |
Fn3-123 |
12 | rs764561909 |
0.2193 | 0.117 | 0.996 | N | 0.653 | 0.29 | None | gnomAD-4.0.0 | 7.12644E-05 | None | None | None | None | N | None | 6.6761E-05 | 6.66844E-05 | None | 0 | 0 | None | 0 | 0 | 7.9674E-05 | 1.09789E-04 | 3.20195E-05 |
| D/E | 32510 |
Fn3-125 |
12 | rs375612373 |
0.4591 | -0.037 | 1.0 | N | 0.382 | 0.272 | 0.170165803431 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 6.55E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 32510 |
Fn3-125 |
12 | rs375612373 |
0.4591 | -0.037 | 1.0 | N | 0.382 | 0.272 | 0.170165803431 | gnomAD-4.0.0 | 1.3698E-06 | None | None | None | None | N | None | 5.98229E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/G | 32510 |
Fn3-125 |
12 | rs1170311014 |
0.4701 | None | 1.0 | N | 0.726 | 0.557 | 0.27855597813 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 32510 |
Fn3-125 |
12 | rs1170311014 |
0.4701 | None | 1.0 | N | 0.726 | 0.557 | 0.27855597813 | gnomAD-4.0.0 | 6.57333E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47042E-05 | 0 | 0 |
| D/H | 32611 |
Fn3-126 |
12 | None | 0.9144 | None | 1.0 | N | 0.687 | 0.457 | 0.378674557249 | gnomAD-4.0.0 | 3.18398E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.546E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 32908 |
Fn3-128 |
13 | None | 0.8194 | None | 1.0 | N | 0.608 | 0.469 | 0.387366425376 | gnomAD-4.0.0 | 6.84248E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65684E-05 |
| D/N | 32908 |
Fn3-128 |
13 | rs267599023 |
0.3982 | 0.419 | 1.0 | N | 0.611 | 0.376 | 0.321108458156 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 0 | 0 |
| D/N | 32908 |
Fn3-128 |
13 | rs267599023 |
0.3982 | 0.419 | 1.0 | N | 0.611 | 0.376 | 0.321108458156 | gnomAD-4.0.0 | 9.57947E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39712E-06 | 6.95652E-05 | 3.31367E-05 |
| D/Y | 32908 |
Fn3-128 |
13 | None | 0.7171 | None | 1.0 | N | 0.645 | 0.482 | 0.736162974464 | gnomAD-4.0.0 | 6.84248E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9952E-07 | 0 | 0 |
| A/G | 33302 |
Fn3-130 |
13 | None | 0.1895 | None | 0.698 | N | 0.465 | 0.247 | 0.372087925617 | gnomAD-4.0.0 | 1.59817E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77685E-05 | None | 0 | 0 | 0 | 0 | 0 |
| A/P | 33302 |
Fn3-130 |
13 | None | 0.9674 | None | 0.971 | N | 0.629 | 0.291 | 0.437207349437 | gnomAD-4.0.0 | 6.85583E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01317E-07 | 0 | 0 |
| A/T | 33302 |
Fn3-130 |
13 | rs1291047229 |
0.1976 | -0.604 | 0.014 | N | 0.293 | 0.144 | 0.260249123532 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| A/T | 33302 |
Fn3-130 |
13 | rs1291047229 |
0.1976 | -0.604 | 0.014 | N | 0.293 | 0.144 | 0.260249123532 | gnomAD-4.0.0 | 2.74233E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60527E-06 | 0 | 0 |
| A/T | 33403 |
Fn3-131 |
12 | None | 0.1293 | None | 0.925 | N | 0.426 | 0.135 | 0.323886383625 | gnomAD-4.0.0 | 7.33229E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.35657E-07 | 0 | 0 |
| D/G | 33700 |
Fn3-132 |
12 | None | 0.454 | None | 0.557 | N | 0.569 | 0.334 | 0.283761946502 | gnomAD-4.0.0 | 1.36839E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79888E-06 | 0 | 0 |
| D/H | 33700 |
Fn3-132 |
12 | rs878858552 |
0.668 | None | 0.984 | N | 0.586 | 0.404 | 0.333906830038 | gnomAD-4.0.0 | 2.73678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59776E-06 | 0 | 0 |
| D/N | 33700 |
Fn3-132 |
12 | None | 0.1897 | None | 0.436 | N | 0.539 | 0.233 | 0.208816687407 | gnomAD-4.0.0 | 6.84194E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65662E-05 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.