Structural position:
- Domain Type: Fn3
- Aligned Position: 16
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F/I | 15670 |
Fn3-1 |
14 | None | 0.4422 | None | 0.012 | N | 0.156 | 0.079 | 0.247322355667 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/D | 15771 |
Fn3-2 |
14 | rs748512074 |
0.1849 | -0.372 | 0.98 | N | 0.419 | 0.382 | 0.218845423259 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.47E-05 | 5.82E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/D | 15771 |
Fn3-2 |
14 | rs748512074 |
0.1849 | -0.372 | 0.98 | N | 0.419 | 0.382 | 0.218845423259 | gnomAD-4.0.0 | 4.78254E-06 | None | None | None | None | N | None | 5.67924E-05 | 4.58358E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 15872 |
Fn3-3 |
14 | rs753053572 |
0.1198 | -0.57 | 0.953 | N | 0.495 | 0.211 | 0.159798565429 | gnomAD-2.1.1 | 4.32E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.75E-05 | None | 0 | 0 | 0 |
| T/S | 15872 |
Fn3-3 |
14 | rs753053572 |
0.1198 | -0.57 | 0.953 | N | 0.495 | 0.211 | 0.159798565429 | gnomAD-4.0.0 | 3.26347E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.05036E-05 | 0 |
| T/P | 16168 |
Fn3-5 |
14 | rs375878254 |
0.8087 | -0.412 | 0.984 | D | 0.495 | 0.536 | 0.368743488249 | gnomAD-4.0.0 | 2.55139E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.0761E-04 | 2.42248E-04 | 2.86438E-06 | 0 | 9.09863E-05 |
| T/R | 16168 |
Fn3-5 |
14 | None | 0.3323 | None | 0.968 | N | 0.519 | 0.357 | 0.431035450679 | gnomAD-4.0.0 | 1.59456E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86453E-06 | 0 | 0 |
| T/I | 16364 |
Fn3-6 |
14 | rs1159477728 |
0.8961 | 0.02 | 1.0 | D | 0.764 | 0.529 | 0.59827724986 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| T/I | 16364 |
Fn3-6 |
14 | rs1159477728 |
0.8961 | 0.02 | 1.0 | D | 0.764 | 0.529 | 0.59827724986 | gnomAD-4.0.0 | 1.59324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78334E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 16364 |
Fn3-6 |
14 | rs1159477728 |
0.2004 | None | 1.0 | D | 0.77 | 0.439 | 0.455909487837 | gnomAD-4.0.0 | 1.59324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86157E-06 | 0 | 0 |
| T/I | 16463 |
Fn3-7 |
14 | rs541307234 |
0.7132 | None | 0.994 | D | 0.409 | 0.49 | 0.584859779323 | gnomAD-4.0.0 | 6.85616E-07 | None | None | None | None | N | None | 3.0003E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 16463 |
Fn3-7 |
14 | None | 0.3017 | -1.133 | 0.998 | N | 0.405 | 0.362 | 0.396794106654 | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.12145E-04 | None | 6.7E-05 | None | 0 | 0 | 0 |
| T/N | 16463 |
Fn3-7 |
14 | None | 0.3017 | -1.133 | 0.998 | N | 0.405 | 0.362 | 0.396794106654 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.95389E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 16463 |
Fn3-7 |
14 | None | 0.3017 | -1.133 | 0.998 | N | 0.405 | 0.362 | 0.396794106654 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| T/N | 16463 |
Fn3-7 |
14 | None | 0.3017 | -1.133 | 0.998 | N | 0.405 | 0.362 | 0.396794106654 | gnomAD-4.0.0 | 6.82967E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.47407E-05 | None | 0 | 0 | 1.69743E-06 | 6.63101E-05 | 1.60406E-05 |
| T/S | 16463 |
Fn3-7 |
14 | rs541307234 |
0.1765 | -1.327 | 0.835 | N | 0.501 | 0.152 | 0.18995819373 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 6.49E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/S | 16463 |
Fn3-7 |
14 | rs541307234 |
0.1765 | -1.327 | 0.835 | N | 0.501 | 0.152 | 0.18995819373 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 16463 |
Fn3-7 |
14 | rs541307234 |
0.1765 | -1.327 | 0.835 | N | 0.501 | 0.152 | 0.18995819373 | gnomAD-4.0.0 | 6.58068E-06 | None | None | None | None | N | None | 2.41406E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 16564 |
Fn3-8 |
14 | rs759568659 |
0.3853 | -1.735 | 0.984 | N | 0.527 | 0.156 | 0.235664433957 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| G/D | 16564 |
Fn3-8 |
14 | rs759568659 |
0.3853 | -1.735 | 0.984 | N | 0.527 | 0.156 | 0.235664433957 | gnomAD-4.0.0 | 1.59344E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.862E-06 | 0 | 0 |
| G/V | 16564 |
Fn3-8 |
14 | rs759568659 |
0.3936 | -0.372 | 0.811 | N | 0.587 | 0.194 | 0.347438807231 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/V | 16564 |
Fn3-8 |
14 | rs759568659 |
0.3936 | -0.372 | 0.811 | N | 0.587 | 0.194 | 0.347438807231 | gnomAD-4.0.0 | 1.59344E-06 | None | None | None | None | N | None | 0 | 2.28927E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 16664 |
Fn3-9 |
14 | rs1171944721 |
0.7581 | -0.024 | 0.994 | D | 0.431 | 0.441 | 0.564429724435 | gnomAD-2.1.1 | 8.23E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.21E-06 | 1.69434E-04 |
| T/I | 16664 |
Fn3-9 |
14 | rs1171944721 |
0.7581 | -0.024 | 0.994 | D | 0.431 | 0.441 | 0.564429724435 | gnomAD-4.0.0 | 7.97939E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79455E-05 | None | 0 | 2.41896E-04 | 5.72692E-06 | 1.43476E-05 | 0 |
| T/A | 16764 |
Fn3-10 |
14 | None | 0.3473 | None | 0.76 | N | 0.441 | 0.263 | 0.332902724076 | gnomAD-4.0.0 | 1.59528E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79626E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 16764 |
Fn3-10 |
14 | rs748125248 |
0.8384 | 0.305 | 0.991 | D | 0.491 | 0.402 | 0.50143340055 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| T/I | 16764 |
Fn3-10 |
14 | rs748125248 |
0.8384 | 0.305 | 0.991 | D | 0.491 | 0.402 | 0.50143340055 | gnomAD-4.0.0 | 2.05492E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.48529E-05 | 0 |
| T/S | 16764 |
Fn3-10 |
14 | None | 0.1643 | None | 0.374 | N | 0.314 | 0.179 | 0.218845423259 | gnomAD-4.0.0 | 3.19057E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.87233E-05 | 0 |
| G/R | 16865 |
Fn3-11 |
14 | rs1191765707 |
0.5383 | -0.809 | 0.968 | N | 0.585 | 0.341 | 0.500994481783 | gnomAD-2.1.1 | 1.79E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 2.06868E-04 | None | 0 | None | 0 | 0 | 0 |
| G/R | 16865 |
Fn3-11 |
14 | rs1191765707 |
0.5383 | -0.809 | 0.968 | N | 0.585 | 0.341 | 0.500994481783 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 9.74279E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 16865 |
Fn3-11 |
14 | rs1191765707 |
0.5383 | -0.809 | 0.968 | N | 0.585 | 0.341 | 0.500994481783 | gnomAD-4.0.0 | 4.33964E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.56607E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/W | 16865 |
Fn3-11 |
14 | None | 0.7328 | None | 0.999 | N | 0.568 | 0.33 | 0.520749599713 | gnomAD-4.0.0 | 1.36902E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79951E-06 | 0 | 0 |
| T/N | 17060 |
Fn3-12 |
14 | None | 0.3019 | None | 1.0 | N | 0.765 | 0.362 | 0.432041664125 | gnomAD-4.0.0 | 1.5936E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86277E-06 | 0 | 0 |
| T/I | 17160 |
Fn3-13 |
14 | None | 0.7585 | None | 1.0 | N | 0.773 | 0.521 | 0.605592448911 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/S | 17160 |
Fn3-13 |
14 | None | 0.1551 | None | 0.999 | N | 0.513 | 0.392 | 0.201204373187 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/G | 17382 |
Fn3-14 |
14 | rs397517607 |
0.4016 | -0.834 | 1.0 | N | 0.674 | 0.334 | 0.401042353794 | gnomAD-2.1.1 | 2.7264E-04 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 2.35356E-03 | None | 0 | 0 | 4.22773E-04 |
| R/G | 17382 |
Fn3-14 |
14 | rs397517607 |
0.4016 | -0.834 | 1.0 | N | 0.674 | 0.334 | 0.401042353794 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 8.285E-04 | 0 |
| R/G | 17382 |
Fn3-14 |
14 | rs397517607 |
0.4016 | -0.834 | 1.0 | N | 0.674 | 0.334 | 0.401042353794 | gnomAD-4.0.0 | 1.39624E-04 | None | None | None | None | N | None | 1.33661E-05 | 5.00551E-05 | None | 0 | 0 | None | 0 | 3.29815E-04 | 4.24025E-06 | 2.27328E-03 | 1.12201E-04 |
| R/S | 17382 |
Fn3-14 |
14 | None | 0.6944 | None | 1.0 | N | 0.707 | 0.341 | 0.238705975628 | gnomAD-4.0.0 | 1.59655E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86254E-06 | 0 | 0 |
| T/A | 17483 |
Fn3-15 |
14 | None | 0.2177 | None | 0.76 | N | 0.491 | 0.318 | 0.191931220699 | gnomAD-4.0.0 | 1.60622E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.42365E-04 | 0 | 0 | 0 |
| S/I | 17582 |
Fn3-16 |
14 | None | 0.6773 | None | 0.681 | N | 0.377 | 0.174 | 0.492134657179 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 17875 |
Fn3-18 |
14 | rs750095768 |
0.9755 | 0.051 | 1.0 | N | 0.769 | 0.432 | 0.551961605406 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.06E-06 | 0 |
| K/E | 18078 |
Fn3-19 |
14 | None | 0.8011 | None | 0.989 | N | 0.467 | 0.328 | 0.317958651998 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 18179 |
Fn3-20 |
14 | None | 0.216 | None | 0.201 | D | 0.354 | 0.147 | 0.227260227426 | gnomAD-4.0.0 | 2.05441E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70014E-06 | 0 | 0 |
| T/I | 18179 |
Fn3-20 |
14 | rs765149899 |
0.7696 | -0.141 | 0.004 | N | 0.214 | 0.317 | 0.311691414656 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/I | 18179 |
Fn3-20 |
14 | rs765149899 |
0.7696 | -0.141 | 0.004 | N | 0.214 | 0.317 | 0.311691414656 | gnomAD-4.0.0 | 1.59458E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86431E-06 | 0 | 0 |
| T/M | 18285 |
Fn3-21 |
14 | rs761825854 |
0.476 | 0.15 | 1.0 | N | 0.679 | 0.427 | 0.525205403968 | gnomAD-2.1.1 | 3.2E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.51E-05 | 0 |
| T/M | 18285 |
Fn3-21 |
14 | rs761825854 |
0.476 | 0.15 | 1.0 | N | 0.679 | 0.427 | 0.525205403968 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.96078E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/M | 18285 |
Fn3-21 |
14 | rs761825854 |
0.476 | 0.15 | 1.0 | N | 0.679 | 0.427 | 0.525205403968 | gnomAD-4.0.0 | 9.48576E-06 | None | None | None | None | N | None | 2.71407E-05 | 0 | None | 0 | 2.29579E-05 | None | 0 | 0 | 7.73757E-06 | 0 | 4.90084E-05 |
| T/A | 18592 |
Fn3-23 |
14 | None | 0.3543 | None | 0.999 | N | 0.503 | 0.495 | 0.253205268125 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/L | 18798 |
Fn3-24 |
15 | rs2052673581 |
0.1128 | None | 0.001 | N | 0.14 | 0.167 | 0.359557344763 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/L | 18798 |
Fn3-24 |
15 | rs2052673581 |
0.1128 | None | 0.001 | N | 0.14 | 0.167 | 0.359557344763 | gnomAD-4.0.0 | 6.57678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47067E-05 | 0 | 0 |
| T/I | 19197 |
Fn3-27 |
15 | None | 0.6494 | None | 1.0 | N | 0.808 | 0.461 | 0.45470266194 | gnomAD-4.0.0 | 6.86581E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01203E-07 | 0 | 0 |
| T/I | 19297 |
Fn3-28 |
14 | None | 0.7744 | None | 0.032 | N | 0.324 | 0.306 | 0.342865806769 | gnomAD-4.0.0 | 1.59534E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43786E-05 | 0 |
| T/S | 19297 |
Fn3-28 |
14 | None | 0.1209 | None | 0.153 | N | 0.198 | 0.143 | 0.144782658237 | gnomAD-4.0.0 | 1.59529E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8659E-06 | 0 | 0 |
| T/A | 19592 |
Fn3-30 |
14 | rs769094173 |
0.1709 | -0.651 | 0.906 | N | 0.375 | 0.243 | 0.32306181527 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| T/A | 19592 |
Fn3-30 |
14 | rs769094173 |
0.1709 | -0.651 | 0.906 | N | 0.375 | 0.243 | 0.32306181527 | gnomAD-4.0.0 | 1.02683E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.34944E-05 | 0 | 0 |
| T/I | 19592 |
Fn3-30 |
14 | rs745441183 |
0.613 | -0.103 | 0.988 | N | 0.369 | 0.443 | 0.482209950775 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| T/I | 19592 |
Fn3-30 |
14 | rs745441183 |
0.613 | -0.103 | 0.988 | N | 0.369 | 0.443 | 0.482209950775 | gnomAD-4.0.0 | 6.84572E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99648E-07 | 0 | 0 |
| T/N | 19592 |
Fn3-30 |
14 | rs745441183 |
0.1377 | None | 0.92 | N | 0.394 | 0.307 | 0.375861065471 | gnomAD-4.0.0 | 3.42286E-06 | None | None | None | None | N | None | 8.97451E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.31477E-05 |
| T/A | 19693 |
Fn3-31 |
14 | rs1218974177 |
0.2473 | None | 0.948 | N | 0.441 | 0.321 | 0.397540356873 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 19693 |
Fn3-31 |
14 | rs1218974177 |
0.2473 | None | 0.948 | N | 0.441 | 0.321 | 0.397540356873 | gnomAD-4.0.0 | 6.57393E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 19693 |
Fn3-31 |
14 | None | 0.8687 | None | 0.998 | N | 0.662 | 0.487 | 0.619139198567 | gnomAD-4.0.0 | 1.59206E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85946E-06 | 0 | 0 |
| R/T | 19890 |
Fn3-32 |
14 | rs751739372 |
0.3483 | -0.122 | 1.0 | N | 0.719 | 0.374 | 0.307332253619 | gnomAD-2.1.1 | 2.91E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.03E-05 | 4.8E-05 | 1.42816E-04 |
| R/T | 19890 |
Fn3-32 |
14 | rs751739372 |
0.3483 | -0.122 | 1.0 | N | 0.719 | 0.374 | 0.307332253619 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/T | 19890 |
Fn3-32 |
14 | rs751739372 |
0.3483 | -0.122 | 1.0 | N | 0.719 | 0.374 | 0.307332253619 | gnomAD-4.0.0 | 7.70929E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.7204E-05 | 0 | 7.19597E-06 | 0 | 0 |
| D/E | 19990 |
Fn3-33 |
14 | rs757340381 |
0.5561 | -0.77 | 1.0 | N | 0.457 | 0.235 | 0.300784259202 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 19990 |
Fn3-33 |
14 | rs757340381 |
0.5561 | -0.77 | 1.0 | N | 0.457 | 0.235 | 0.300784259202 | gnomAD-4.0.0 | 3.18482E-06 | None | None | None | None | N | None | 0 | 4.57792E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 19990 |
Fn3-33 |
14 | None | 0.73 | None | 1.0 | N | 0.766 | 0.427 | 0.398283496042 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| T/I | 20185 |
Fn3-34 |
15 | None | 0.6288 | None | 0.991 | N | 0.462 | 0.424 | 0.427829143865 | gnomAD-4.0.0 | 2.40067E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62504E-06 | 0 | 0 |
| T/A | 20284 |
Fn3-35 |
14 | None | 0.1504 | None | 0.046 | N | 0.111 | 0.165 | 0.193865811164 | gnomAD-4.0.0 | 1.44039E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.44375E-05 | 0 | 3.66327E-05 |
| S/C | 20384 |
Fn3-36 |
14 | rs778981748 |
0.2322 | -0.477 | 0.931 | N | 0.522 | 0.284 | 0.319970858106 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| S/C | 20384 |
Fn3-36 |
14 | rs778981748 |
0.2322 | -0.477 | 0.931 | N | 0.522 | 0.284 | 0.319970858106 | gnomAD-4.0.0 | 1.36943E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79973E-06 | 0 | 0 |
| S/G | 20384 |
Fn3-36 |
14 | None | 0.1503 | None | 0.334 | N | 0.424 | 0.125 | 0.104622674875 | gnomAD-4.0.0 | 6.84714E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99866E-07 | 0 | 0 |
| S/N | 20384 |
Fn3-36 |
14 | rs771365105 |
0.2403 | -1.065 | 0.334 | N | 0.489 | 0.101 | 0.0482279557977 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 6.5E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 20384 |
Fn3-36 |
14 | rs771365105 |
0.2403 | -1.065 | 0.334 | N | 0.489 | 0.101 | 0.0482279557977 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 20384 |
Fn3-36 |
14 | rs771365105 |
0.2403 | -1.065 | 0.334 | N | 0.489 | 0.101 | 0.0482279557977 | gnomAD-4.0.0 | 2.56651E-06 | None | None | None | None | N | None | 1.69388E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39646E-06 | 0 | 0 |
| G/E | 20681 |
Fn3-38 |
14 | rs1031977069 |
0.9599 | None | 1.0 | N | 0.827 | 0.438 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/E | 20681 |
Fn3-38 |
14 | rs1031977069 |
0.9599 | None | 1.0 | N | 0.827 | 0.438 | None | gnomAD-4.0.0 | 6.5767E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47098E-05 | 0 | 0 |
| G/R | 20681 |
Fn3-38 |
14 | rs778208423 |
0.9843 | -0.962 | 1.0 | N | 0.832 | 0.432 | 0.5763749866 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| G/R | 20681 |
Fn3-38 |
14 | rs778208423 |
0.9843 | -0.962 | 1.0 | N | 0.832 | 0.432 | 0.5763749866 | gnomAD-4.0.0 | 1.5918E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85941E-06 | 0 | 0 |
| S/C | 20877 |
Fn3-39 |
14 | rs1406472135 |
0.1425 | -0.259 | 0.002 | N | 0.365 | 0.232 | 0.289474373501 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| S/C | 20877 |
Fn3-39 |
14 | rs1406472135 |
0.1425 | -0.259 | 0.002 | N | 0.365 | 0.232 | 0.289474373501 | gnomAD-4.0.0 | 4.79825E-06 | None | None | None | None | N | None | 0 | 2.28864E-05 | None | 0 | 0 | None | 0 | 0 | 5.71899E-06 | 0 | 0 |
| S/R | 20976 |
Fn3-40 |
14 | rs1225927295 |
0.84 | -0.557 | 0.971 | N | 0.525 | 0.238 | 0.279776271856 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/R | 20976 |
Fn3-40 |
14 | rs1225927295 |
0.84 | -0.557 | 0.971 | N | 0.525 | 0.238 | 0.279776271856 | gnomAD-4.0.0 | 3.42197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49805E-06 | 0 | 0 |
| T/I | 21077 |
Fn3-41 |
14 | rs2049450214 |
0.9351 | None | 1.0 | N | 0.761 | 0.445 | 0.468669884856 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 21077 |
Fn3-41 |
14 | rs2049450214 |
0.9351 | None | 1.0 | N | 0.761 | 0.445 | 0.468669884856 | gnomAD-4.0.0 | 6.25166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.54942E-06 | 0 | 0 |
| T/N | 21077 |
Fn3-41 |
14 | None | 0.3612 | None | 1.0 | N | 0.756 | 0.397 | 0.302459207581 | gnomAD-4.0.0 | 6.90806E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0768E-07 | 0 | 0 |
| T/S | 21279 |
Fn3-42 |
14 | rs1276354995 |
0.1159 | -0.684 | 0.103 | N | 0.153 | 0.101 | 0.110078149338 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 0 | 2.94E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/S | 21279 |
Fn3-42 |
14 | rs1276354995 |
0.1159 | -0.684 | 0.103 | N | 0.153 | 0.101 | 0.110078149338 | gnomAD-4.0.0 | 1.6145E-06 | None | None | None | None | N | None | 0 | 2.31342E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 21573 |
Fn3-44 |
15 | rs727504967 |
0.5216 | -0.029 | 1.0 | N | 0.437 | 0.308 | 0.0806252709748 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| D/E | 21573 |
Fn3-44 |
15 | rs727504967 |
0.5216 | -0.029 | 1.0 | N | 0.437 | 0.308 | 0.0806252709748 | gnomAD-4.0.0 | 6.84424E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.52589E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 21573 |
Fn3-44 |
15 | rs760347376 |
0.5714 | -0.227 | 1.0 | N | 0.726 | 0.412 | 0.268660756437 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| D/H | 21573 |
Fn3-44 |
15 | rs760347376 |
0.5714 | -0.227 | 1.0 | N | 0.726 | 0.412 | 0.268660756437 | gnomAD-4.0.0 | 6.36955E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.21014E-04 |
| N/K | 21672 |
Fn3-45 |
14 | rs1452681242 |
0.5128 | -0.231 | 0.684 | N | 0.291 | 0.238 | 0.194818534648 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| N/K | 21672 |
Fn3-45 |
14 | rs1452681242 |
0.5128 | -0.231 | 0.684 | N | 0.291 | 0.238 | 0.194818534648 | gnomAD-4.0.0 | 2.73835E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59932E-06 | 0 | 0 |
| N/S | 21672 |
Fn3-45 |
14 | None | 0.0798 | None | 0.078 | N | 0.097 | 0.101 | 0.132336055621 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| N/Y | 21672 |
Fn3-45 |
14 | None | 0.2091 | None | 0.792 | N | 0.455 | 0.285 | 0.338834610459 | gnomAD-4.0.0 | 1.5935E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43435E-05 | 0 |
| T/S | 21770 |
Fn3-46 |
14 | None | 0.1533 | None | 0.001 | N | 0.195 | 0.149 | 0.143124449307 | gnomAD-4.0.0 | 1.63093E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.93748E-06 | 0 | 0 |
| Y/C | 21969 |
Fn3-47 |
14 | rs777698555 |
0.3108 | 0.118 | 0.015 | N | 0.265 | 0.201 | None | gnomAD-2.1.1 | 8.49E-05 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 4.67E-05 | 1.69974E-04 | 0 |
| Y/C | 21969 |
Fn3-47 |
14 | rs777698555 |
0.3108 | 0.118 | 0.015 | N | 0.265 | 0.201 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.41E-05 | 0 | 2.94E-05 | 0 | 0 |
| Y/C | 21969 |
Fn3-47 |
14 | rs777698555 |
0.3108 | 0.118 | 0.015 | N | 0.265 | 0.201 | None | gnomAD-4.0.0 | 4.21819E-05 | None | None | None | None | N | None | 0 | 1.66973E-05 | None | 0 | 0 | None | 4.68911E-05 | 0 | 4.66566E-05 | 0 | 1.44268E-04 |
| T/I | 22068 |
Fn3-48 |
14 | None | 0.893 | None | 0.642 | N | 0.509 | 0.354 | 0.4018988957 | gnomAD-4.0.0 | 1.59372E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86049E-06 | 0 | 0 |
| T/I | 22169 |
Fn3-49 |
14 | None | 0.9516 | None | 1.0 | N | 0.785 | 0.458 | 0.543778624532 | gnomAD-4.0.0 | 1.61167E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89256E-06 | 0 | 0 |
| S/P | 22367 |
Fn3-50 |
14 | rs72646873 |
0.9359 | -0.662 | 0.949 | N | 0.457 | 0.356 | None | gnomAD-2.1.1 | 1.70763E-03 | None | None | None | None | N | None | 5.37368E-04 | 9.07132E-04 | None | 3.19767E-03 | 0 | None | 2.42099E-03 | None | 1.19971E-04 | 2.4619E-03 | 1.12771E-03 |
| S/P | 22367 |
Fn3-50 |
14 | rs72646873 |
0.9359 | -0.662 | 0.949 | N | 0.457 | 0.356 | None | gnomAD-3.1.2 | 1.88022E-03 | None | None | None | None | N | None | 7.47817E-04 | 2.88373E-03 | 0 | 4.03226E-03 | 0 | None | 1.88395E-04 | 0 | 2.63243E-03 | 2.48242E-03 | 1.91205E-03 |
| S/P | 22367 |
Fn3-50 |
14 | rs72646873 |
0.9359 | -0.662 | 0.949 | N | 0.457 | 0.356 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 1E-03 | None | None | None | 4.1E-03 | None |
| S/P | 22367 |
Fn3-50 |
14 | rs72646873 |
0.9359 | -0.662 | 0.949 | N | 0.457 | 0.356 | None | gnomAD-4.0.0 | 3.29725E-03 | None | None | None | None | N | None | 6.53229E-04 | 1.48412E-03 | None | 3.44781E-03 | 0 | None | 1.56299E-04 | 6.61376E-04 | 3.96279E-03 | 2.13084E-03 | 3.15543E-03 |
| S/P | 22464 |
Fn3-51 |
14 | rs1430161296 |
0.8842 | -0.645 | 0.106 | N | 0.429 | 0.199 | 0.115124310173 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.52742E-04 | None | 0 | None | 0 | 0 | 0 |
| S/P | 22464 |
Fn3-51 |
14 | rs1430161296 |
0.8842 | -0.645 | 0.106 | N | 0.429 | 0.199 | 0.115124310173 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9425E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 22464 |
Fn3-51 |
14 | rs1430161296 |
0.8842 | -0.645 | 0.106 | N | 0.429 | 0.199 | 0.115124310173 | gnomAD-4.0.0 | 6.40934E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.42966E-05 | None | 0 | 0 | 9.57822E-06 | 0 | 0 |
| T/I | 22657 |
Fn3-52 |
15 | None | 0.7379 | None | 1.0 | N | 0.741 | 0.503 | 0.540288329166 | gnomAD-4.0.0 | 2.05324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79929E-06 | 1.15945E-05 | 0 |
| T/R | 22854 |
Fn3-54 |
14 | rs2046780936 |
0.5727 | None | 0.994 | N | 0.683 | 0.471 | 0.529510553188 | gnomAD-4.0.0 | 1.64253E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.93962E-06 | 0 | 0 |
| T/A | 23448 |
Fn3-58 |
14 | None | 0.1177 | None | 0.371 | N | 0.441 | 0.228 | 0.151104730317 | gnomAD-4.0.0 | 1.59277E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41429E-04 | 0 | 0 | 0 |
| T/R | 23448 |
Fn3-58 |
14 | None | 0.1912 | None | 0.999 | N | 0.455 | 0.352 | 0.568465717781 | gnomAD-4.0.0 | 1.59278E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86218E-06 | 0 | 0 |
| T/I | 23545 |
Fn3-59 |
14 | None | 0.9467 | None | 0.942 | D | 0.437 | 0.479 | 0.603539076606 | gnomAD-4.0.0 | 6.84245E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99536E-07 | 0 | 0 |
| T/S | 23545 |
Fn3-59 |
14 | rs1247049807 |
0.1373 | -1.204 | 0.006 | N | 0.157 | 0.068 | 0.154104182512 | gnomAD-4.0.0 | 6.84245E-07 | None | None | None | None | N | None | 0 | 2.23604E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 23740 |
Fn3-60 |
15 | rs757597284 |
0.3643 | -0.147 | 0.805 | N | 0.573 | 0.434 | 0.531727546574 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.31105E-04 | None | 0 | 0 | 0 |
| S/L | 23740 |
Fn3-60 |
15 | rs757597284 |
0.3643 | -0.147 | 0.805 | N | 0.573 | 0.434 | 0.531727546574 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/L | 23740 |
Fn3-60 |
15 | rs757597284 |
0.3643 | -0.147 | 0.805 | N | 0.573 | 0.434 | 0.531727546574 | gnomAD-4.0.0 | 8.06087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47884E-07 | 1.20874E-04 | 1.60241E-05 |
| S/P | 23740 |
Fn3-60 |
15 | rs779202830 |
0.9783 | -0.744 | 0.983 | N | 0.643 | 0.393 | 0.378498632473 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/P | 23740 |
Fn3-60 |
15 | rs779202830 |
0.9783 | -0.744 | 0.983 | N | 0.643 | 0.393 | 0.378498632473 | gnomAD-4.0.0 | 1.59345E-06 | None | None | None | None | N | None | 0 | 2.2899E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 24235 |
Fn3-64 |
14 | rs1477680606 |
0.73 | None | 0.997 | D | 0.736 | 0.48 | 0.591526896791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 24235 |
Fn3-64 |
14 | rs1477680606 |
0.73 | None | 0.997 | D | 0.736 | 0.48 | 0.591526896791 | gnomAD-4.0.0 | 1.97551E-06 | None | None | None | None | N | None | 2.78963E-05 | 2.26552E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 24235 |
Fn3-64 |
14 | rs1477680606 |
0.1646 | None | 0.235 | N | 0.275 | 0.306 | 0.341460817117 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 24336 |
Fn3-65 |
14 | rs1708845261 |
0.1227 | None | 0.896 | N | 0.412 | 0.162 | 0.239305524855 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 24336 |
Fn3-65 |
14 | rs1708845261 |
0.1227 | None | 0.896 | N | 0.412 | 0.162 | 0.239305524855 | gnomAD-4.0.0 | 6.57601E-06 | None | None | None | None | N | None | 0 | 6.55308E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 24336 |
Fn3-65 |
14 | None | 0.3778 | None | 0.896 | N | 0.449 | 0.2 | 0.232513804876 | gnomAD-4.0.0 | 1.59227E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78164E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 24532 |
Fn3-66 |
14 | None | 0.5719 | None | 0.999 | N | 0.798 | 0.482 | 0.575346514103 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/P | 24532 |
Fn3-66 |
14 | rs752664615 |
0.8316 | -0.591 | 0.997 | D | 0.795 | 0.509 | 0.484545746072 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/A | 24629 |
Fn3-67 |
14 | rs1708480217 |
0.5572 | None | 0.039 | N | 0.197 | 0.253 | 0.192905019026 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06697E-04 | 0 |
| T/A | 24629 |
Fn3-67 |
14 | rs1708480217 |
0.5572 | None | 0.039 | N | 0.197 | 0.253 | 0.192905019026 | gnomAD-4.0.0 | 4.9589E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 8.78542E-05 | 0 |
| T/R | 24822 |
Fn3-68 |
15 | rs1479629836 |
0.5795 | None | 0.967 | N | 0.627 | 0.393 | 0.509346181843 | gnomAD-4.0.0 | 4.7761E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57859E-06 | 0 | 0 |
| S/F | 24921 |
Fn3-69 |
14 | rs1373803284 |
0.2777 | -1.302 | 0.427 | N | 0.499 | 0.299 | 0.419335720491 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/F | 24921 |
Fn3-69 |
14 | rs1373803284 |
0.2777 | -1.302 | 0.427 | N | 0.499 | 0.299 | 0.419335720491 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 24921 |
Fn3-69 |
14 | rs1373803284 |
0.2777 | -1.302 | 0.427 | N | 0.499 | 0.299 | 0.419335720491 | gnomAD-4.0.0 | 2.56381E-06 | None | None | None | None | N | None | 0 | 3.39132E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 25019 |
Fn3-70 |
14 | None | 0.2939 | None | 0.79 | N | 0.359 | 0.372 | 0.347659731818 | gnomAD-4.0.0 | 1.36908E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.04134E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 25019 |
Fn3-70 |
14 | None | 0.3092 | None | 0.995 | N | 0.685 | 0.4 | 0.411401001288 | gnomAD-4.0.0 | 4.10723E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39931E-06 | 0 | 0 |
| T/P | 25317 |
Fn3-72 |
14 | rs762723439 |
0.8366 | -0.566 | 0.971 | D | 0.473 | 0.446 | 0.565793286963 | gnomAD-4.0.0 | 1.59182E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| T/A | 25711 |
Fn3-75 |
14 | rs887610262 |
0.4903 | -0.838 | 0.386 | N | 0.45 | 0.427 | 0.201204373187 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/A | 25711 |
Fn3-75 |
14 | rs887610262 |
0.4903 | -0.838 | 0.386 | N | 0.45 | 0.427 | 0.201204373187 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 25711 |
Fn3-75 |
14 | rs887610262 |
0.4903 | -0.838 | 0.386 | N | 0.45 | 0.427 | 0.201204373187 | gnomAD-4.0.0 | 6.09028E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.02504E-06 | 0 | 3.40275E-05 |
| T/I | 25711 |
Fn3-75 |
14 | None | 0.9432 | None | 0.997 | N | 0.673 | 0.472 | 0.518585293439 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| S/R | 25904 |
Fn3-76 |
15 | None | 0.9378 | None | 0.967 | D | 0.659 | 0.385 | 0.268211541103 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| S/P | 26003 |
Fn3-77 |
14 | None | 0.8849 | None | 0.896 | N | 0.393 | 0.345 | 0.230578612272 | gnomAD-4.0.0 | 1.59201E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| K/T | 26101 |
Fn3-78 |
14 | rs749914062 |
0.1197 | -0.597 | 0.007 | N | 0.115 | 0.144 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
| K/T | 26101 |
Fn3-78 |
14 | rs749914062 |
0.1197 | -0.597 | 0.007 | N | 0.115 | 0.144 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/T | 26101 |
Fn3-78 |
14 | rs749914062 |
0.1197 | -0.597 | 0.007 | N | 0.115 | 0.144 | None | gnomAD-4.0.0 | 1.53786E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.3941E-05 | 0 | 5.69087E-05 |
| T/N | 26300 |
Fn3-79 |
15 | rs750541239 |
0.2822 | -0.622 | 0.988 | N | 0.702 | 0.469 | 0.419835214384 | gnomAD-2.1.1 | 2.05E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.52E-05 | 0 |
| T/N | 26300 |
Fn3-79 |
15 | rs750541239 |
0.2822 | -0.622 | 0.988 | N | 0.702 | 0.469 | 0.419835214384 | gnomAD-4.0.0 | 1.51092E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.98417E-05 | 0 | 0 |
| A/V | 26399 |
Fn3-80 |
14 | None | 0.2589 | None | 0.379 | N | 0.293 | 0.301 | 0.247322355667 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 26500 |
Fn3-81 |
14 | rs1172084404 |
0.1892 | -0.671 | 0.76 | N | 0.446 | 0.253 | 0.152612264143 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/A | 26500 |
Fn3-81 |
14 | rs1172084404 |
0.1892 | -0.671 | 0.76 | N | 0.446 | 0.253 | 0.152612264143 | gnomAD-4.0.0 | 2.05398E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69861E-06 | 0 | 0 |
| T/I | 26500 |
Fn3-81 |
14 | rs1480393355 |
0.8678 | 0.053 | 0.991 | N | 0.485 | 0.498 | 0.393006254552 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.96E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 26500 |
Fn3-81 |
14 | rs1480393355 |
0.8678 | 0.053 | 0.991 | N | 0.485 | 0.498 | 0.393006254552 | gnomAD-4.0.0 | 2.73885E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.82731E-05 | 2.51927E-05 | None | 0 | 0 | 1.79907E-06 | 0 | 0 |
| T/S | 26500 |
Fn3-81 |
14 | rs1480393355 |
0.1073 | -1.001 | 0.17 | N | 0.328 | 0.119 | 0.0762999501168 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/S | 26500 |
Fn3-81 |
14 | rs1480393355 |
0.1073 | -1.001 | 0.17 | N | 0.328 | 0.119 | 0.0762999501168 | gnomAD-4.0.0 | 1.36942E-06 | None | None | None | None | N | None | 0 | 2.23634E-05 | None | 0 | 0 | None | 0 | 0 | 8.99533E-07 | 0 | 0 |
| R/K | 26696 |
Fn3-82 |
14 | rs769866606 |
0.0575 | -1.328 | None | N | 0.039 | 0.107 | 0.0716867268079 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| R/K | 26696 |
Fn3-82 |
14 | rs769866606 |
0.0575 | -1.328 | None | N | 0.039 | 0.107 | 0.0716867268079 | gnomAD-4.0.0 | 1.36865E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99598E-07 | 1.15947E-05 | 0 |
| R/S | 26696 |
Fn3-82 |
14 | None | 0.2975 | None | 0.005 | N | 0.273 | 0.051 | 0.101711395817 | gnomAD-4.0.0 | 1.59188E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85954E-06 | 0 | 0 |
| S/A | 26793 |
Fn3-83 |
14 | rs960039859 |
0.2469 | -0.501 | 0.309 | N | 0.329 | 0.08 | 0.149567049428 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/A | 26793 |
Fn3-83 |
14 | rs960039859 |
0.2469 | -0.501 | 0.309 | N | 0.329 | 0.08 | 0.149567049428 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 26793 |
Fn3-83 |
14 | rs960039859 |
0.2469 | -0.501 | 0.309 | N | 0.329 | 0.08 | 0.149567049428 | gnomAD-4.0.0 | 1.9727E-05 | None | None | None | None | N | None | 7.24358E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 26986 |
Fn3-84 |
15 | rs1389359522 |
0.4422 | -0.649 | 0.892 | N | 0.537 | 0.281 | 0.19670166235 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| S/N | 26986 |
Fn3-84 |
15 | rs1389359522 |
0.4422 | -0.649 | 0.892 | N | 0.537 | 0.281 | 0.19670166235 | gnomAD-4.0.0 | 1.16338E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52929E-05 | 0 | 0 |
| T/I | 27183 |
Fn3-86 |
14 | rs1559331817 |
0.8449 | None | 0.994 | D | 0.761 | 0.477 | 0.684252380218 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/I | 27183 |
Fn3-86 |
14 | rs1559331817 |
0.8449 | None | 0.994 | D | 0.761 | 0.477 | 0.684252380218 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85901E-06 | 0 | 0 |
| T/A | 27383 |
Fn3-87 |
15 | rs768253514 |
0.2916 | -0.882 | 0.37 | N | 0.215 | 0.204 | 0.18995819373 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| T/A | 27383 |
Fn3-87 |
15 | rs768253514 |
0.2916 | -0.882 | 0.37 | N | 0.215 | 0.204 | 0.18995819373 | gnomAD-4.0.0 | 6.84242E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52054E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 27383 |
Fn3-87 |
15 | rs746519411 |
0.7381 | 0.006 | 0.997 | N | 0.473 | 0.394 | 0.482283251092 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| T/I | 27383 |
Fn3-87 |
15 | rs746519411 |
0.7381 | 0.006 | 0.997 | N | 0.473 | 0.394 | 0.482283251092 | gnomAD-4.0.0 | 5.47393E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29657E-06 | 0 | 1.65667E-05 |
| T/I | 27482 |
Fn3-88 |
14 | None | 0.6865 | None | 0.638 | N | 0.489 | 0.519 | 0.407767136052 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 27779 |
Fn3-90 |
14 | rs1410411613 |
0.4815 | 0.063 | 0.864 | N | 0.478 | 0.145 | 0.201204373187 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| K/N | 27779 |
Fn3-90 |
14 | rs1410411613 |
0.4815 | 0.063 | 0.864 | N | 0.478 | 0.145 | 0.201204373187 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/N | 27779 |
Fn3-90 |
14 | rs1410411613 |
0.4815 | 0.063 | 0.864 | N | 0.478 | 0.145 | 0.201204373187 | gnomAD-4.0.0 | 2.56416E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78833E-06 | 0 | 0 |
| S/T | 28068 |
Fn3-92 |
14 | rs72648219 |
0.0908 | -0.559 | 0.999 | N | 0.466 | 0.218 | None | gnomAD-2.1.1 | 5.01E-05 | None | None | None | None | N | None | 5.78656E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/T | 28068 |
Fn3-92 |
14 | rs72648219 |
0.0908 | -0.559 | 0.999 | N | 0.466 | 0.218 | None | gnomAD-3.1.2 | 1.77438E-04 | None | None | None | None | N | None | 5.54966E-04 | 1.96438E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| S/T | 28068 |
Fn3-92 |
14 | rs72648219 |
0.0908 | -0.559 | 0.999 | N | 0.466 | 0.218 | None | gnomAD-4.0.0 | 2.54116E-05 | None | None | None | None | N | None | 4.93966E-04 | 5.003E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60164E-05 |
| T/I | 28167 |
Fn3-93 |
14 | rs1159274489 |
0.7266 | None | 0.983 | N | 0.681 | 0.473 | 0.55911886355 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 28167 |
Fn3-93 |
14 | rs1159274489 |
0.7266 | None | 0.983 | N | 0.681 | 0.473 | 0.55911886355 | gnomAD-4.0.0 | 6.57281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46994E-05 | 0 | 0 |
| T/K | 28265 |
Fn3-94 |
14 | rs376874908 |
0.6271 | None | 1.0 | N | 0.775 | 0.479 | None | gnomAD-4.0.0 | 1.5912E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85809E-06 | 0 | 0 |
| T/N | 28464 |
Fn3-95 |
15 | rs1234280926 |
0.2165 | None | 1.0 | N | 0.772 | 0.395 | 0.374076547971 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 28464 |
Fn3-95 |
15 | rs1234280926 |
0.2165 | None | 1.0 | N | 0.772 | 0.395 | 0.374076547971 | gnomAD-4.0.0 | 3.71824E-06 | None | None | None | None | N | None | 6.67254E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47588E-07 | 0 | 0 |
| T/N | 28563 |
Fn3-96 |
14 | rs1186514108 |
0.1454 | -0.796 | 0.1 | N | 0.274 | 0.212 | 0.255270683199 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 5.82E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/N | 28563 |
Fn3-96 |
14 | rs1186514108 |
0.1454 | -0.796 | 0.1 | N | 0.274 | 0.212 | 0.255270683199 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 28563 |
Fn3-96 |
14 | rs1186514108 |
0.1454 | -0.796 | 0.1 | N | 0.274 | 0.212 | 0.255270683199 | gnomAD-4.0.0 | 3.84537E-06 | None | None | None | None | N | None | 0 | 5.08906E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 28664 |
Fn3-97 |
14 | rs370285001 |
0.1198 | -0.743 | 0.041 | N | 0.428 | 0.058 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/A | 28664 |
Fn3-97 |
14 | rs370285001 |
0.1198 | -0.743 | 0.041 | N | 0.428 | 0.058 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| G/A | 28664 |
Fn3-97 |
14 | rs370285001 |
0.1198 | -0.743 | 0.041 | N | 0.428 | 0.058 | None | gnomAD-4.0.0 | 1.31525E-05 | None | None | None | None | N | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| G/D | 28664 |
Fn3-97 |
14 | None | 0.2611 | None | 0.324 | N | 0.553 | 0.207 | 0.152612264143 | gnomAD-4.0.0 | 1.59159E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41546E-04 | 0 | 0 | 0 |
| G/S | 28664 |
Fn3-97 |
14 | None | 0.0729 | None | 0.001 | N | 0.156 | 0.043 | 0.0297737177859 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 28664 |
Fn3-97 |
14 | rs370285001 |
0.2628 | -0.489 | 0.193 | N | 0.562 | 0.15 | 0.513846082701 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| G/V | 28664 |
Fn3-97 |
14 | rs370285001 |
0.2628 | -0.489 | 0.193 | N | 0.562 | 0.15 | 0.513846082701 | gnomAD-4.0.0 | 6.36637E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.14362E-05 | 0 | 0 |
| T/I | 28858 |
Fn3-98 |
14 | rs1456110995 |
0.6315 | -0.054 | 1.0 | N | 0.733 | 0.479 | 0.475430695062 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/I | 28858 |
Fn3-98 |
14 | rs1456110995 |
0.6315 | -0.054 | 1.0 | N | 0.733 | 0.479 | 0.475430695062 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43291E-05 | 0 |
| T/I | 29151 |
Fn3-100 |
15 | None | 0.6728 | None | 0.971 | N | 0.524 | 0.439 | 0.357724736475 | gnomAD-4.0.0 | 1.59194E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85783E-06 | 0 | 0 |
| T/A | 29646 |
Fn3-104 |
14 | None | 0.1625 | None | 0.581 | N | 0.452 | 0.34 | 0.202949470691 | gnomAD-4.0.0 | 1.60226E-06 | None | None | None | None | N | None | 5.76834E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 29646 |
Fn3-104 |
14 | rs1338218286 |
0.6893 | 0.041 | 0.908 | N | 0.765 | 0.44 | 0.481915485015 | gnomAD-2.1.1 | 4.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.14E-06 | 0 |
| T/I | 29646 |
Fn3-104 |
14 | rs1338218286 |
0.6893 | 0.041 | 0.908 | N | 0.765 | 0.44 | 0.481915485015 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 29646 |
Fn3-104 |
14 | rs1338218286 |
0.6893 | 0.041 | 0.908 | N | 0.765 | 0.44 | 0.481915485015 | gnomAD-4.0.0 | 1.24283E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.6974E-06 | 0 | 0 |
| T/N | 29646 |
Fn3-104 |
14 | rs1338218286 |
0.1731 | None | 0.01 | N | 0.316 | 0.28 | 0.250039746154 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 29646 |
Fn3-104 |
14 | rs1338218286 |
0.1731 | None | 0.01 | N | 0.316 | 0.28 | 0.250039746154 | gnomAD-4.0.0 | 1.24283E-06 | None | None | None | None | N | None | 2.68291E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 29747 |
Fn3-105 |
14 | None | 0.4297 | None | 0.999 | N | 0.476 | 0.435 | 0.244539031024 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| T/S | 29747 |
Fn3-105 |
14 | rs2154152263 |
0.1815 | -0.608 | 0.999 | N | 0.51 | 0.308 | 0.211220785272 | gnomAD-2.1.1 | 4.1885E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 3.35821E-03 | None | 0 | 0 | 3.4118E-04 |
| T/S | 29747 |
Fn3-105 |
14 | rs2154152263 |
0.1815 | -0.608 | 0.999 | N | 0.51 | 0.308 | 0.211220785272 | gnomAD-3.1.2 | 1.117E-04 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 3.52259E-03 | 0 |
| T/S | 29747 |
Fn3-105 |
14 | rs2154152263 |
0.1815 | -0.608 | 0.999 | N | 0.51 | 0.308 | 0.211220785272 | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 3.1E-03 | None |
| T/S | 29747 |
Fn3-105 |
14 | rs2154152263 |
0.1815 | -0.608 | 0.999 | N | 0.51 | 0.308 | 0.211220785272 | gnomAD-4.0.0 | 6.56444E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47003E-05 | 0 | 0 |
| S/C | 29946 |
Fn3-106 |
14 | rs1019701643 |
0.1596 | -0.216 | 1.0 | N | 0.497 | 0.435 | 0.465038187318 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| S/C | 29946 |
Fn3-106 |
14 | rs1019701643 |
0.1596 | -0.216 | 1.0 | N | 0.497 | 0.435 | 0.465038187318 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| S/C | 29946 |
Fn3-106 |
14 | rs1019701643 |
0.1596 | -0.216 | 1.0 | N | 0.497 | 0.435 | 0.465038187318 | gnomAD-4.0.0 | 7.69724E-06 | None | None | None | None | N | None | 1.69142E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.19721E-05 | 0 | 0 |
| S/F | 29946 |
Fn3-106 |
14 | rs1019701643 |
0.3615 | -0.776 | 0.999 | N | 0.592 | 0.385 | 0.564133873757 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.41849E-04 | None | 0 | None | 0 | 0 | 0 |
| S/F | 29946 |
Fn3-106 |
14 | rs1019701643 |
0.3615 | -0.776 | 0.999 | N | 0.592 | 0.385 | 0.564133873757 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 29946 |
Fn3-106 |
14 | rs1019701643 |
0.3615 | -0.776 | 0.999 | N | 0.592 | 0.385 | 0.564133873757 | gnomAD-4.0.0 | 6.57151E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 30043 |
Fn3-107 |
14 | rs757241713 |
0.1675 | -1.092 | 0.489 | N | 0.449 | 0.172 | 0.166414681773 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/A | 30043 |
Fn3-107 |
14 | rs757241713 |
0.1675 | -1.092 | 0.489 | N | 0.449 | 0.172 | 0.166414681773 | gnomAD-4.0.0 | 1.36834E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52003E-05 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| T/I | 30043 |
Fn3-107 |
14 | None | 0.7503 | None | 0.971 | D | 0.68 | 0.448 | 0.637981554935 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/S | 30043 |
Fn3-107 |
14 | None | 0.0841 | None | 0.058 | N | 0.23 | 0.044 | 0.128392430309 | gnomAD-4.0.0 | 2.05251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69829E-06 | 0 | 0 |
| T/I | 30435 |
Fn3-110 |
14 | rs1060500591 |
0.9369 | -0.049 | 1.0 | N | 0.771 | 0.526 | 0.661599691914 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/I | 30435 |
Fn3-110 |
14 | rs1060500591 |
0.9369 | -0.049 | 1.0 | N | 0.771 | 0.526 | 0.661599691914 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| T/I | 30435 |
Fn3-110 |
14 | rs1060500591 |
0.9369 | -0.049 | 1.0 | N | 0.771 | 0.526 | 0.661599691914 | gnomAD-4.0.0 | 6.19929E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.39248E-05 | 0 | 1.60143E-05 |
| T/I | 30633 |
Fn3-111 |
15 | rs780636599 |
0.5488 | None | 0.971 | N | 0.653 | 0.434 | 0.403040389579 | gnomAD-4.0.0 | 6.91676E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.07436E-07 | 0 | 0 |
| T/N | 30633 |
Fn3-111 |
15 | None | 0.1537 | None | 0.89 | N | 0.613 | 0.259 | None | gnomAD-4.0.0 | 6.91676E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.67864E-05 |
| S/C | 31126 |
Fn3-115 |
14 | None | 0.1812 | None | 0.995 | N | 0.476 | 0.489 | 0.430010490656 | gnomAD-4.0.0 | 6.84181E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51915E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 31126 |
Fn3-115 |
14 | None | 0.0861 | None | 0.722 | N | 0.412 | 0.214 | 0.252162846088 | gnomAD-4.0.0 | 6.84181E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65645E-05 |
| S/R | 31126 |
Fn3-115 |
14 | None | 0.7636 | None | 0.901 | N | 0.449 | 0.286 | 0.294206760003 | gnomAD-4.0.0 | 1.59112E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85794E-06 | 0 | 0 |
| S/L | 31322 |
Fn3-116 |
15 | rs879213271 |
0.1909 | None | 0.885 | N | 0.478 | 0.308 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/K | 31519 |
Fn3-118 |
14 | rs554140295 |
0.7767 | -0.707 | 0.999 | N | 0.715 | 0.425 | 0.464612977235 | gnomAD-2.1.1 | 4.21E-06 | None | None | None | None | N | None | 6.5E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/K | 31519 |
Fn3-118 |
14 | rs554140295 |
0.7767 | -0.707 | 0.999 | N | 0.715 | 0.425 | 0.464612977235 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 31519 |
Fn3-118 |
14 | rs554140295 |
0.7767 | -0.707 | 0.999 | N | 0.715 | 0.425 | 0.464612977235 | gnomAD-4.0.0 | 1.88002E-06 | None | None | None | None | N | None | 2.68147E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.56412E-07 | 0 | 0 |
| T/R | 31519 |
Fn3-118 |
14 | rs554140295 |
0.7629 | -0.284 | 0.999 | N | 0.775 | 0.409 | 0.526385394563 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| T/I | 31721 |
Fn3-119 |
14 | None | 0.7582 | None | 1.0 | N | 0.755 | 0.527 | 0.515715180578 | gnomAD-4.0.0 | 6.84617E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99956E-07 | 0 | 0 |
| T/A | 31922 |
Fn3-121 |
14 | rs773198280 |
0.2142 | -0.776 | 0.999 | N | 0.507 | 0.4 | 0.353336612579 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/A | 31922 |
Fn3-121 |
14 | rs773198280 |
0.2142 | -0.776 | 0.999 | N | 0.507 | 0.4 | 0.353336612579 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 31922 |
Fn3-121 |
14 | rs773198280 |
0.2142 | -0.776 | 0.999 | N | 0.507 | 0.4 | 0.353336612579 | gnomAD-4.0.0 | 2.56923E-06 | None | None | None | None | N | None | 1.69273E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40365E-06 | 0 | 0 |
| T/S | 31922 |
Fn3-121 |
14 | rs769771566 |
0.107 | -1.131 | 0.999 | N | 0.531 | 0.299 | 0.317084106153 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| T/S | 31922 |
Fn3-121 |
14 | rs769771566 |
0.107 | -1.131 | 0.999 | N | 0.531 | 0.299 | 0.317084106153 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/S | 31922 |
Fn3-121 |
14 | rs769771566 |
0.107 | -1.131 | 0.999 | N | 0.531 | 0.299 | 0.317084106153 | gnomAD-4.0.0 | 5.13805E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.61298E-06 | 0 | 0 |
| T/I | 32215 |
Fn3-123 |
14 | rs975713554 |
0.9171 | None | 0.999 | N | 0.75 | 0.523 | 0.553591132476 | gnomAD-4.0.0 | 6.84184E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99449E-07 | 0 | 0 |
| T/S | 32215 |
Fn3-123 |
14 | rs975713554 |
0.1707 | -1.11 | 0.965 | N | 0.495 | 0.337 | 0.338110398507 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
| T/S | 32215 |
Fn3-123 |
14 | rs975713554 |
0.1707 | -1.11 | 0.965 | N | 0.495 | 0.337 | 0.338110398507 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/S | 32215 |
Fn3-123 |
14 | rs975713554 |
0.1707 | -1.11 | 0.965 | N | 0.495 | 0.337 | 0.338110398507 | gnomAD-4.0.0 | 2.47876E-05 | None | None | None | None | N | None | 4.0062E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.05132E-05 | 0 | 1.60092E-05 |
| D/N | 32413 |
Fn3-124 |
15 | rs1695055645 |
0.144 | None | 0.822 | N | 0.471 | 0.255 | 0.139678290688 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.30924E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 32413 |
Fn3-124 |
15 | rs1695055645 |
0.144 | None | 0.822 | N | 0.471 | 0.255 | 0.139678290688 | gnomAD-4.0.0 | 1.31453E-05 | None | None | None | None | N | None | 0 | 1.30924E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 32512 |
Fn3-125 |
14 | rs1220964715 |
0.5239 | None | 0.999 | N | 0.641 | 0.461 | 0.635165634531 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 32613 |
Fn3-126 |
14 | None | 0.8529 | None | 1.0 | N | 0.791 | 0.448 | 0.635465298753 | gnomAD-4.0.0 | 6.00175E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56268E-06 | 0 | 0 |
| Q/H | 32809 |
Fn3-127 |
15 | rs1271415335 |
0.3081 | None | 0.99 | N | 0.465 | 0.238 | 0.0806252709748 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/H | 32809 |
Fn3-127 |
15 | rs1271415335 |
0.3081 | None | 0.99 | N | 0.465 | 0.238 | 0.0806252709748 | gnomAD-4.0.0 | 2.5622E-06 | None | None | None | None | N | None | 3.38215E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/P | 32809 |
Fn3-127 |
15 | rs1060500398 |
0.6844 | 0.037 | 0.97 | N | 0.453 | 0.358 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| Q/P | 32809 |
Fn3-127 |
15 | rs1060500398 |
0.6844 | 0.037 | 0.97 | N | 0.453 | 0.358 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Q/P | 32809 |
Fn3-127 |
15 | rs1060500398 |
0.6844 | 0.037 | 0.97 | N | 0.453 | 0.358 | None | gnomAD-4.0.0 | 3.09854E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23804E-06 | 0 | 0 |
| S/T | 33011 |
Fn3-129 |
14 | rs78814506 |
0.083 | -0.856 | 0.007 | N | 0.081 | 0.098 | None | gnomAD-2.1.1 | 8.76109E-04 | None | None | None | None | N | None | 1.24131E-04 | 8.54E-05 | None | 3.90854E-04 | 1.143E-02 | None | 1.65859E-04 | None | 0 | 7.85E-06 | 7.06814E-04 |
| S/T | 33011 |
Fn3-129 |
14 | rs78814506 |
0.083 | -0.856 | 0.007 | N | 0.081 | 0.098 | None | gnomAD-3.1.2 | 6.11376E-04 | None | None | None | None | N | None | 4.83E-05 | 1.63784E-03 | 0 | 0 | 1.13812E-02 | None | 0 | 0 | 1.47E-05 | 0 | 2.86807E-03 |
| S/T | 33011 |
Fn3-129 |
14 | rs78814506 |
0.083 | -0.856 | 0.007 | N | 0.081 | 0.098 | None | 1000 genomes | 2.39617E-03 | None | None | None | None | N | None | 0 | 0 | None | None | 1.19E-02 | 0 | None | None | None | 0 | None |
| S/T | 33011 |
Fn3-129 |
14 | rs78814506 |
0.083 | -0.856 | 0.007 | N | 0.081 | 0.098 | None | gnomAD-4.0.0 | 3.37505E-04 | None | None | None | None | N | None | 4.00545E-05 | 4.67852E-04 | None | 2.70874E-04 | 6.69016E-03 | None | 0 | 0 | 7.63566E-06 | 6.6139E-05 | 3.04409E-03 |
| L/S | 33304 |
Fn3-130 |
15 | rs1691995704 |
0.7222 | None | 1.0 | N | 0.775 | 0.511 | 0.645115249394 | gnomAD-4.0.0 | 1.59635E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.7767E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 33405 |
Fn3-131 |
14 | None | 0.7472 | None | 0.998 | N | 0.591 | 0.551 | 0.639332231701 | gnomAD-4.0.0 | 7.28526E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44163E-05 | 0 |
| T/R | 33405 |
Fn3-131 |
14 | None | 0.426 | None | 0.998 | D | 0.596 | 0.439 | 0.744763759119 | gnomAD-4.0.0 | 7.28526E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32545E-07 | 0 | 0 |
| S/P | 33702 |
Fn3-132 |
14 | rs751545599 |
0.9631 | -0.562 | 0.932 | N | 0.448 | 0.4 | 0.277730125212 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/P | 33702 |
Fn3-132 |
14 | rs751545599 |
0.9631 | -0.562 | 0.932 | N | 0.448 | 0.4 | 0.277730125212 | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85801E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.