Structural position:
- Domain Type: Fn3
- Aligned Position: 19
- Secondary Structure Element: e
- Secondary Structure Region: β-strand B
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S/P | 15875 |
Fn3-3 |
17 | rs1274510932 |
0.9745 | None | 1.0 | D | 0.81 | 0.536 | 0.569101917167 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 16071 |
Fn3-4 |
17 | rs794727332 |
0.1337 | 0.371 | 0.669 | D | 0.56 | 0.438 | None | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| S/L | 16071 |
Fn3-4 |
17 | rs794727332 |
0.1337 | 0.371 | 0.669 | D | 0.56 | 0.438 | None | gnomAD-4.0.0 | 2.19121E-05 | None | None | None | None | N | None | 2.99509E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.7E-05 | 0 | 1.65876E-05 |
| S/L | 16367 |
Fn3-6 |
17 | None | 0.233 | None | 0.989 | D | 0.665 | 0.513 | 0.829753570234 | gnomAD-4.0.0 | 3.18638E-06 | None | None | None | None | N | None | 0 | 4.57875E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/S | 16466 |
Fn3-7 |
17 | None | 0.0975 | None | 0.062 | N | 0.247 | 0.112 | 0.110078149338 | gnomAD-4.0.0 | 6.85563E-07 | None | None | None | None | N | None | 3.00012E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 16466 |
Fn3-7 |
17 | rs755998484 |
0.1556 | -1.792 | 0.929 | N | 0.455 | 0.102 | 0.239901079897 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| A/T | 16466 |
Fn3-7 |
17 | rs755998484 |
0.1556 | -1.792 | 0.929 | N | 0.455 | 0.102 | 0.239901079897 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 16466 |
Fn3-7 |
17 | rs755998484 |
0.1556 | -1.792 | 0.929 | N | 0.455 | 0.102 | 0.239901079897 | gnomAD-4.0.0 | 2.48357E-06 | None | None | None | None | N | None | 0 | 1.67678E-05 | None | 0 | 0 | None | 0 | 0 | 2.54601E-06 | 0 | 0 |
| H/P | 16767 |
Fn3-10 |
17 | rs373892279 |
0.9672 | -0.663 | 0.999 | D | 0.766 | 0.466 | None | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| H/P | 16767 |
Fn3-10 |
17 | rs373892279 |
0.9672 | -0.663 | 0.999 | D | 0.766 | 0.466 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/P | 16767 |
Fn3-10 |
17 | rs373892279 |
0.9672 | -0.663 | 0.999 | D | 0.766 | 0.466 | None | gnomAD-4.0.0 | 6.57981E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47197E-05 | 0 | 0 |
| H/Y | 16767 |
Fn3-10 |
17 | rs2056436094 |
0.1579 | None | 0.219 | N | 0.123 | 0.275 | 0.231231049324 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| S/P | 17063 |
Fn3-12 |
17 | rs758563428 |
0.9947 | -0.568 | 0.991 | D | 0.734 | 0.506 | 0.485991781493 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/P | 17063 |
Fn3-12 |
17 | rs758563428 |
0.9947 | -0.568 | 0.991 | D | 0.734 | 0.506 | 0.485991781493 | gnomAD-4.0.0 | 1.36924E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31981E-05 | 0 |
| S/L | 17385 |
Fn3-14 |
17 | rs749493479 |
0.2645 | -0.021 | 1.0 | D | 0.742 | 0.584 | 0.737954416556 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.91E-06 | 0 |
| S/L | 17385 |
Fn3-14 |
17 | rs749493479 |
0.2645 | -0.021 | 1.0 | D | 0.742 | 0.584 | 0.737954416556 | gnomAD-4.0.0 | 3.19139E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.8664E-05 | 0 |
| M/I | 17780 |
Fn3-17 |
17 | None | 0.7789 | None | 0.704 | N | 0.289 | 0.25 | 0.63454643552 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/T | 17780 |
Fn3-17 |
17 | rs879003153 |
0.5782 | -0.919 | 0.92 | N | 0.33 | 0.281 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.65E-05 | 0 | 0 |
| M/T | 17780 |
Fn3-17 |
17 | rs879003153 |
0.5782 | -0.919 | 0.92 | N | 0.33 | 0.281 | None | gnomAD-4.0.0 | 1.59343E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88281E-05 | 0 | 0 | 0 | 0 |
| T/I | 17878 |
Fn3-18 |
17 | None | 0.773 | None | 0.984 | N | 0.727 | 0.31 | 0.462461958149 | gnomAD-4.0.0 | 1.60683E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89039E-06 | 0 | 0 |
| S/F | 18081 |
Fn3-19 |
17 | None | 0.7412 | None | 1.0 | N | 0.825 | 0.497 | 0.689175263246 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| S/T | 18081 |
Fn3-19 |
17 | None | 0.288 | None | 0.999 | N | 0.485 | 0.369 | 0.379707525713 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 18182 |
Fn3-20 |
17 | rs1470054004 |
0.2144 | None | 0.997 | D | 0.675 | 0.472 | 0.737862570375 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/L | 18182 |
Fn3-20 |
17 | rs1470054004 |
0.2144 | None | 0.997 | D | 0.675 | 0.472 | 0.737862570375 | gnomAD-4.0.0 | 2.56678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39737E-06 | 1.34271E-05 | 0 |
| S/C | 18288 |
Fn3-21 |
17 | None | 0.2998 | None | 0.965 | N | 0.694 | 0.349 | 0.467161347466 | gnomAD-4.0.0 | 6.94182E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.08371E-07 | 0 | 0 |
| S/R | 18495 |
Fn3-22 |
17 | rs1213190093 |
0.834 | -0.687 | 0.934 | N | 0.527 | 0.411 | 0.4897983601 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/R | 18495 |
Fn3-22 |
17 | rs1213190093 |
0.834 | -0.687 | 0.934 | N | 0.527 | 0.411 | 0.4897983601 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 18495 |
Fn3-22 |
17 | rs1213190093 |
0.834 | -0.687 | 0.934 | N | 0.527 | 0.411 | 0.4897983601 | gnomAD-4.0.0 | 6.84559E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9985E-07 | 0 | 0 |
| T/P | 18595 |
Fn3-23 |
17 | None | 0.941 | None | 0.997 | N | 0.768 | 0.526 | 0.52468985305 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/R | 18595 |
Fn3-23 |
17 | rs770499179 |
0.3086 | -0.859 | 0.993 | N | 0.769 | 0.42 | None | gnomAD-2.1.1 | 4.49E-05 | None | None | None | None | N | None | 0 | 2.0404E-04 | None | 0 | 0 | None | 0 | None | 0 | 3.47E-05 | 1.64582E-04 |
| T/R | 18595 |
Fn3-23 |
17 | rs770499179 |
0.3086 | -0.859 | 0.993 | N | 0.769 | 0.42 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 0 | 5.90706E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 18595 |
Fn3-23 |
17 | rs770499179 |
0.3086 | -0.859 | 0.993 | N | 0.769 | 0.42 | None | gnomAD-4.0.0 | 1.9058E-05 | None | None | None | None | N | None | 0 | 2.7787E-04 | None | 0 | 0 | None | 0 | 0 | 1.20472E-05 | 0 | 1.64761E-05 |
| Q/H | 18801 |
Fn3-24 |
18 | None | 0.1604 | None | 0.003 | N | 0.153 | 0.065 | 0.141422826196 | gnomAD-4.0.0 | 6.96302E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.24614E-05 | 0 |
| S/C | 18900 |
Fn3-25 |
17 | rs1256105535 |
0.116 | None | 1.0 | N | 0.7 | 0.443 | 0.536661227952 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.93751E-06 | 0 | 0 |
| S/F | 19200 |
Fn3-27 |
18 | None | 0.2543 | None | 1.0 | N | 0.86 | 0.483 | 0.571693661435 | gnomAD-4.0.0 | 1.60272E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.45921E-05 | 0 |
| T/A | 19300 |
Fn3-28 |
17 | rs1303630569 |
0.0892 | -0.858 | 0.012 | N | 0.347 | 0.118 | 0.119812018005 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.57E-05 | None | 0 | 0 | 0 |
| T/A | 19300 |
Fn3-28 |
17 | rs1303630569 |
0.0892 | -0.858 | 0.012 | N | 0.347 | 0.118 | 0.119812018005 | gnomAD-4.0.0 | 4.78292E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.31047E-05 | 0 |
| T/N | 19300 |
Fn3-28 |
17 | rs979451740 |
0.1341 | None | 0.062 | N | 0.495 | 0.123 | 0.270889551736 | gnomAD-4.0.0 | 2.73922E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.9541E-04 | 0 | 0 | 0 |
| Y/F | 19496 |
Fn3-29 |
18 | None | 0.0724 | None | None | N | 0.131 | 0.126 | 0.293147016451 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/S | 19496 |
Fn3-29 |
18 | None | 0.0642 | None | 0.117 | N | 0.513 | 0.253 | 0.442567846599 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 19595 |
Fn3-30 |
17 | rs1354326243 |
0.2064 | -0.796 | 0.999 | N | 0.841 | 0.478 | 0.506006782367 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| S/F | 19595 |
Fn3-30 |
17 | rs1354326243 |
0.2064 | -0.796 | 0.999 | N | 0.841 | 0.478 | 0.506006782367 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/F | 19595 |
Fn3-30 |
17 | rs1354326243 |
0.2064 | -0.796 | 0.999 | N | 0.841 | 0.478 | 0.506006782367 | gnomAD-4.0.0 | 5.12789E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.57712E-06 | 0 | 0 |
| S/L | 19696 |
Fn3-31 |
17 | None | 0.3328 | None | 1.0 | D | 0.753 | 0.506 | 0.73762428413 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/L | 19893 |
Fn3-32 |
17 | rs766590578 |
0.3382 | 0.279 | 1.0 | N | 0.753 | 0.529 | 0.785336147086 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.1E-06 | 0 |
| S/L | 19893 |
Fn3-32 |
17 | rs766590578 |
0.3382 | 0.279 | 1.0 | N | 0.753 | 0.529 | 0.785336147086 | gnomAD-4.0.0 | 3.193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.73082E-06 | 0 | 0 |
| S/P | 19893 |
Fn3-32 |
17 | None | 0.9923 | None | 1.0 | D | 0.827 | 0.565 | 0.588862895911 | gnomAD-4.0.0 | 3.19289E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.73069E-06 | 0 | 0 |
| E/Q | 19993 |
Fn3-33 |
17 | None | 0.2292 | None | 0.957 | N | 0.326 | 0.176 | 0.267299060538 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| H/R | 20188 |
Fn3-34 |
18 | None | 0.1818 | None | 0.055 | N | 0.567 | 0.119 | 0.183819452728 | gnomAD-4.0.0 | 1.36877E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79927E-06 | 0 | 0 |
| H/Y | 20188 |
Fn3-34 |
18 | None | 0.0598 | None | None | N | 0.138 | 0.148 | 0.0716867268079 | gnomAD-4.0.0 | 1.59217E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85984E-06 | 0 | 0 |
| A/T | 20287 |
Fn3-35 |
17 | None | 0.1274 | None | 0.885 | N | 0.537 | 0.236 | 0.353974658523 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/Y | 20585 |
Fn3-37 |
17 | rs574383177 |
0.1577 | -0.194 | 0.794 | N | 0.611 | 0.207 | 0.476205827853 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| N/Y | 20585 |
Fn3-37 |
17 | rs574383177 |
0.1577 | -0.194 | 0.794 | N | 0.611 | 0.207 | 0.476205827853 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| N/Y | 20585 |
Fn3-37 |
17 | rs574383177 |
0.1577 | -0.194 | 0.794 | N | 0.611 | 0.207 | 0.476205827853 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| N/Y | 20585 |
Fn3-37 |
17 | rs574383177 |
0.1577 | -0.194 | 0.794 | N | 0.611 | 0.207 | 0.476205827853 | gnomAD-4.0.0 | 1.85967E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.29453E-05 | 0 |
| F/V | 20684 |
Fn3-38 |
17 | rs2049802658 |
0.8452 | None | 0.999 | N | 0.593 | 0.261 | 0.774620572007 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/V | 20684 |
Fn3-38 |
17 | rs2049802658 |
0.8452 | None | 0.999 | N | 0.593 | 0.261 | 0.774620572007 | gnomAD-4.0.0 | 6.57696E-06 | None | None | None | None | I | None | 2.41336E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 20880 |
Fn3-39 |
17 | None | 0.1136 | None | 0.122 | N | 0.136 | 0.199 | 0.194818534648 | gnomAD-4.0.0 | 1.60055E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41196E-04 | 0 | 0 | 0 |
| R/S | 20880 |
Fn3-39 |
17 | rs1181982003 |
0.6257 | -1.329 | 0.961 | N | 0.569 | 0.239 | 0.16115917748 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/S | 20880 |
Fn3-39 |
17 | rs1181982003 |
0.6257 | -1.329 | 0.961 | N | 0.569 | 0.239 | 0.16115917748 | gnomAD-4.0.0 | 2.05779E-06 | None | None | None | None | N | None | 0 | 4.47708E-05 | None | 0 | 0 | None | 0 | 0 | 8.99586E-07 | 0 | 0 |
| E/A | 20979 |
Fn3-40 |
17 | rs375728230 |
0.2389 | -1.029 | 0.999 | N | 0.701 | 0.376 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/A | 20979 |
Fn3-40 |
17 | rs375728230 |
0.2389 | -1.029 | 0.999 | N | 0.701 | 0.376 | None | gnomAD-4.0.0 | 1.36917E-06 | None | None | None | None | N | None | 2.99007E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65766E-05 |
| E/D | 20979 |
Fn3-40 |
17 | None | 0.2391 | None | 0.999 | N | 0.563 | 0.203 | 0.28722502521 | gnomAD-4.0.0 | 2.05318E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7992E-06 | 0 | 1.657E-05 |
| E/G | 20979 |
Fn3-40 |
17 | rs375728230 |
0.2738 | -1.398 | 1.0 | N | 0.76 | 0.385 | 0.35139820857 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| E/G | 20979 |
Fn3-40 |
17 | rs375728230 |
0.2738 | -1.398 | 1.0 | N | 0.76 | 0.385 | 0.35139820857 | gnomAD-4.0.0 | 6.84584E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99902E-07 | 0 | 0 |
| E/K | 20979 |
Fn3-40 |
17 | None | 0.5982 | None | 0.999 | N | 0.596 | 0.366 | 0.32053947749 | gnomAD-4.0.0 | 6.84585E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99909E-07 | 0 | 0 |
| E/Q | 20979 |
Fn3-40 |
17 | rs1306891128 |
0.2944 | -0.907 | 1.0 | N | 0.657 | 0.273 | 0.286081765059 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 20979 |
Fn3-40 |
17 | rs1306891128 |
0.2944 | -0.907 | 1.0 | N | 0.657 | 0.273 | 0.286081765059 | gnomAD-4.0.0 | 6.84585E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52551E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 21080 |
Fn3-41 |
17 | rs769809225 |
0.2323 | -0.552 | 0.76 | N | 0.423 | 0.216 | 0.201204373187 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.35E-05 | None | 0 | 0 | 0 |
| S/A | 21080 |
Fn3-41 |
17 | rs769809225 |
0.2323 | -0.552 | 0.76 | N | 0.423 | 0.216 | 0.201204373187 | gnomAD-4.0.0 | 1.61541E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44898E-05 | 0 |
| S/I | 21382 |
Fn3-43 |
17 | rs759348008 |
0.545 | 0.088 | 0.998 | N | 0.783 | 0.411 | 0.768050980893 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.64E-05 | 0 | 0 |
| S/I | 21382 |
Fn3-43 |
17 | rs759348008 |
0.545 | 0.088 | 0.998 | N | 0.783 | 0.411 | 0.768050980893 | gnomAD-4.0.0 | 1.59289E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88246E-05 | 0 | 0 | 0 | 0 |
| C/S | 21675 |
Fn3-45 |
17 | None | 0.2468 | None | 0.028 | N | 0.257 | 0.33 | 0.413635276047 | gnomAD-4.0.0 | 1.59268E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8603E-06 | 0 | 0 |
| R/C | 21972 |
Fn3-47 |
17 | rs755916258 |
0.3529 | -1.516 | 0.999 | N | 0.596 | 0.375 | None | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| R/C | 21972 |
Fn3-47 |
17 | rs755916258 |
0.3529 | -1.516 | 0.999 | N | 0.596 | 0.375 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/C | 21972 |
Fn3-47 |
17 | rs755916258 |
0.3529 | -1.516 | 0.999 | N | 0.596 | 0.375 | None | gnomAD-4.0.0 | 1.92258E-05 | None | None | None | None | N | None | 4.00994E-05 | 0 | None | 0 | 0 | None | 0 | 1.65017E-04 | 2.20506E-05 | 0 | 1.60272E-05 |
| R/H | 21972 |
Fn3-47 |
17 | rs200217934 |
0.1392 | -2.16 | 0.081 | N | 0.381 | 0.13 | None | gnomAD-2.1.1 | 7.53E-05 | None | None | None | None | N | None | 4.14E-05 | 5.67E-05 | None | 0 | 0 | None | 6.55E-05 | None | 4.01E-05 | 1.17782E-04 | 0 |
| R/H | 21972 |
Fn3-47 |
17 | rs200217934 |
0.1392 | -2.16 | 0.081 | N | 0.381 | 0.13 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.02999E-04 | 0 | 0 |
| R/H | 21972 |
Fn3-47 |
17 | rs200217934 |
0.1392 | -2.16 | 0.081 | N | 0.381 | 0.13 | None | gnomAD-4.0.0 | 8.80622E-05 | None | None | None | None | N | None | 1.33708E-05 | 5.00701E-05 | None | 0 | 0 | None | 0 | 0 | 1.11096E-04 | 4.3956E-05 | 4.80785E-05 |
| H/P | 22071 |
Fn3-48 |
17 | rs968902463 |
0.9719 | None | 0.523 | N | 0.639 | 0.234 | 0.367425347029 | gnomAD-4.0.0 | 6.84663E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99705E-07 | 0 | 0 |
| H/R | 22071 |
Fn3-48 |
17 | rs968902463 |
0.294 | None | 0.351 | N | 0.354 | 0.138 | 0.244539031024 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/R | 22071 |
Fn3-48 |
17 | rs968902463 |
0.294 | None | 0.351 | N | 0.354 | 0.138 | 0.244539031024 | gnomAD-4.0.0 | 1.86024E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54347E-06 | 0 | 0 |
| S/Y | 22172 |
Fn3-49 |
17 | rs1455920569 |
0.6627 | -0.731 | 0.999 | N | 0.777 | 0.417 | 0.749682748319 | gnomAD-2.1.1 | 4.22E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.7301E-04 |
| S/Y | 22172 |
Fn3-49 |
17 | rs1455920569 |
0.6627 | -0.731 | 0.999 | N | 0.777 | 0.417 | 0.749682748319 | gnomAD-4.0.0 | 1.60848E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.42601E-04 | 0 | 0 | 0 |
| S/F | 22467 |
Fn3-51 |
17 | None | 0.1889 | None | 0.938 | N | 0.685 | 0.319 | 0.617388661746 | gnomAD-4.0.0 | 1.59227E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86026E-06 | 0 | 0 |
| S/P | 22467 |
Fn3-51 |
17 | rs1470231213 |
0.9609 | None | 0.984 | D | 0.645 | 0.462 | 0.44770609447 | gnomAD-4.0.0 | 6.8439E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99661E-07 | 0 | 0 |
| S/T | 22467 |
Fn3-51 |
17 | None | 0.0895 | None | 0.103 | N | 0.31 | 0.22 | 0.232513804876 | gnomAD-4.0.0 | 6.8439E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99661E-07 | 0 | 0 |
| A/T | 22660 |
Fn3-52 |
18 | None | 0.1419 | None | 0.999 | N | 0.653 | 0.296 | 0.301455362545 | gnomAD-4.0.0 | 1.59239E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86007E-06 | 0 | 0 |
| S/A | 22759 |
Fn3-53 |
17 | None | 0.0863 | None | 0.003 | D | 0.209 | 0.188 | 0.279776271856 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 23155 |
Fn3-56 |
17 | None | 0.3115 | None | 0.317 | N | 0.652 | 0.161 | 0.288352970974 | gnomAD-4.0.0 | 6.84347E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99588E-07 | 0 | 0 |
| T/S | 23155 |
Fn3-56 |
17 | rs761306433 |
0.0833 | -1.385 | None | N | 0.194 | 0.054 | 0.104622674875 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/S | 23155 |
Fn3-56 |
17 | rs761306433 |
0.0833 | -1.385 | None | N | 0.194 | 0.054 | 0.104622674875 | gnomAD-4.0.0 | 1.71087E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.24897E-05 | 0 | 0 |
| S/P | 23256 |
Fn3-57 |
17 | rs1710100033 |
0.9941 | None | 0.984 | D | 0.637 | 0.459 | 0.363751660372 | gnomAD-4.0.0 | 2.84574E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.66584E-06 | 0 | 0 |
| S/R | 23451 |
Fn3-58 |
17 | rs754456949 |
0.8126 | None | 1.0 | N | 0.795 | 0.468 | 0.414670632993 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 23451 |
Fn3-58 |
17 | rs754456949 |
0.8126 | None | 1.0 | N | 0.795 | 0.468 | 0.414670632993 | gnomAD-4.0.0 | 6.57834E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47124E-05 | 0 | 0 |
| S/T | 23451 |
Fn3-58 |
17 | rs1339742394 |
0.0898 | -0.85 | 0.065 | D | 0.359 | 0.168 | 0.156986980423 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/T | 23451 |
Fn3-58 |
17 | rs1339742394 |
0.0898 | -0.85 | 0.065 | D | 0.359 | 0.168 | 0.156986980423 | gnomAD-4.0.0 | 3.18474E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.8659E-05 | 0 |
| T/I | 23940 |
Fn3-62 |
17 | rs1553610793 |
0.2617 | None | 0.491 | N | 0.565 | 0.279 | 0.382761230579 | gnomAD-4.0.0 | 3.18354E-06 | None | None | None | None | N | None | 5.65867E-05 | 0 | None | 0 | 2.77932E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 23940 |
Fn3-62 |
17 | None | 0.2557 | None | 0.491 | D | 0.503 | 0.259 | 0.508046185061 | gnomAD-4.0.0 | 3.18354E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85896E-06 | 1.43308E-05 | 0 |
| S/L | 24238 |
Fn3-64 |
17 | rs786205303 |
0.2181 | 0.008 | 0.959 | D | 0.675 | 0.404 | 0.714212821129 | gnomAD-2.1.1 | 9.64E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.97E-05 | 0 |
| S/L | 24238 |
Fn3-64 |
17 | rs786205303 |
0.2181 | 0.008 | 0.959 | D | 0.675 | 0.404 | 0.714212821129 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/L | 24238 |
Fn3-64 |
17 | rs786205303 |
0.2181 | 0.008 | 0.959 | D | 0.675 | 0.404 | 0.714212821129 | gnomAD-4.0.0 | 4.41065E-05 | None | None | None | None | N | None | 2.78995E-05 | 0 | None | 0 | 0 | None | 0 | 1.77117E-04 | 5.27979E-05 | 0 | 6.84861E-05 |
| S/C | 24535 |
Fn3-66 |
17 | None | 0.108 | None | 1.0 | N | 0.756 | 0.474 | 0.678686674281 | gnomAD-4.0.0 | 6.84357E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65695E-05 |
| S/F | 24535 |
Fn3-66 |
17 | rs201804005 |
0.2359 | None | 1.0 | N | 0.8 | 0.468 | 0.829790380963 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/F | 24535 |
Fn3-66 |
17 | rs201804005 |
0.2359 | None | 1.0 | N | 0.8 | 0.468 | 0.829790380963 | gnomAD-4.0.0 | 6.57428E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47046E-05 | 0 | 0 |
| S/P | 24535 |
Fn3-66 |
17 | None | 0.9956 | None | 0.997 | D | 0.761 | 0.532 | 0.488477830397 | gnomAD-4.0.0 | 1.36869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79918E-06 | 0 | 0 |
| S/Y | 24535 |
Fn3-66 |
17 | rs201804005 |
0.2749 | -0.966 | 1.0 | N | 0.797 | 0.482 | None | gnomAD-2.1.1 | 4.43256E-04 | None | None | None | None | N | None | 0 | 8.49E-05 | None | 7.54936E-03 | 0 | None | 1.63463E-04 | None | 3.19949E-04 | 2.19099E-04 | 2.81215E-04 |
| S/Y | 24535 |
Fn3-66 |
17 | rs201804005 |
0.2749 | -0.966 | 1.0 | N | 0.797 | 0.482 | None | gnomAD-3.1.2 | 3.81308E-04 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 1.06567E-02 | 0 | None | 3.76506E-04 | 0 | 2.20569E-04 | 0 | 4.78011E-04 |
| S/Y | 24535 |
Fn3-66 |
17 | rs201804005 |
0.2749 | -0.966 | 1.0 | N | 0.797 | 0.482 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| S/Y | 24535 |
Fn3-66 |
17 | rs201804005 |
0.2749 | -0.966 | 1.0 | N | 0.797 | 0.482 | None | gnomAD-4.0.0 | 3.2291E-04 | None | None | None | None | N | None | 1.33305E-05 | 5.001E-05 | None | 8.41557E-03 | 0 | None | 4.53083E-04 | 1.65235E-04 | 1.56831E-04 | 1.20799E-04 | 6.72366E-04 |
| S/I | 24825 |
Fn3-68 |
18 | rs753816472 |
0.6125 | 0.283 | 0.89 | D | 0.738 | 0.358 | 0.782224416147 | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.4833E-04 | None | 0 | None | 0 | 0 | 0 |
| S/I | 24825 |
Fn3-68 |
18 | rs753816472 |
0.6125 | 0.283 | 0.89 | D | 0.738 | 0.358 | 0.782224416147 | gnomAD-4.0.0 | 2.73748E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.57423E-05 | None | 0 | 0 | 0 | 0 | 1.65711E-05 |
| S/N | 24825 |
Fn3-68 |
18 | rs753816472 |
0.3048 | -1.189 | 0.822 | D | 0.569 | 0.269 | 0.292062946507 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| S/N | 24825 |
Fn3-68 |
18 | rs753816472 |
0.3048 | -1.189 | 0.822 | D | 0.569 | 0.269 | 0.292062946507 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 24825 |
Fn3-68 |
18 | rs753816472 |
0.3048 | -1.189 | 0.822 | D | 0.569 | 0.269 | 0.292062946507 | gnomAD-4.0.0 | 8.67795E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18685E-05 | 0 | 0 |
| S/T | 24825 |
Fn3-68 |
18 | None | 0.1751 | None | 0.822 | D | 0.567 | 0.238 | 0.275215494804 | gnomAD-4.0.0 | 2.73748E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69879E-06 | 0 | 1.65711E-05 |
| S/Y | 25022 |
Fn3-70 |
17 | rs374537008 |
0.2038 | -0.561 | 0.995 | N | 0.742 | 0.42 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/Y | 25022 |
Fn3-70 |
17 | rs374537008 |
0.2038 | -0.561 | 0.995 | N | 0.742 | 0.42 | None | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 25221 |
Fn3-71 |
18 | rs745540831 |
0.1148 | -0.703 | 0.999 | N | 0.61 | 0.204 | 0.344251166708 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14916E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/R | 25221 |
Fn3-71 |
18 | rs745540831 |
0.1148 | -0.703 | 0.999 | N | 0.61 | 0.204 | 0.344251166708 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 25221 |
Fn3-71 |
18 | rs745540831 |
0.1148 | -0.703 | 0.999 | N | 0.61 | 0.204 | 0.344251166708 | gnomAD-4.0.0 | 2.03018E-06 | None | None | None | None | N | None | 3.49675E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 25320 |
Fn3-72 |
17 | rs772816442 |
0.1441 | -0.32 | 0.773 | N | 0.423 | 0.345 | 0.331365685468 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.36E-05 | 0 |
| S/A | 25320 |
Fn3-72 |
17 | rs772816442 |
0.1441 | -0.32 | 0.773 | N | 0.423 | 0.345 | 0.331365685468 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| S/A | 25320 |
Fn3-72 |
17 | rs772816442 |
0.1441 | -0.32 | 0.773 | N | 0.423 | 0.345 | 0.331365685468 | gnomAD-4.0.0 | 2.2313E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.79748E-05 | 0 | 4.80446E-05 |
| S/P | 25320 |
Fn3-72 |
17 | rs772816442 |
0.9962 | -0.05 | 0.983 | D | 0.741 | 0.531 | 0.518752145996 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| S/P | 25320 |
Fn3-72 |
17 | rs772816442 |
0.9962 | -0.05 | 0.983 | D | 0.741 | 0.531 | 0.518752145996 | gnomAD-4.0.0 | 6.84311E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99567E-07 | 0 | 0 |
| S/L | 25617 |
Fn3-74 |
17 | None | 0.1673 | None | 0.999 | D | 0.648 | 0.47 | 0.829797144985 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/N | 25907 |
Fn3-76 |
18 | None | 0.2025 | None | 0.944 | N | 0.523 | 0.275 | 0.270889551736 | gnomAD-4.0.0 | 1.59253E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78443E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 26006 |
Fn3-77 |
17 | rs749079480 |
0.083 | None | None | N | 0.193 | 0.073 | 0.104622674875 | gnomAD-4.0.0 | 1.59204E-06 | None | None | None | None | N | None | 0 | 2.28749E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 26006 |
Fn3-77 |
17 | rs749079480 |
0.0822 | -0.908 | 0.001 | N | 0.199 | 0.048 | 0.0846915920261 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| S/T | 26006 |
Fn3-77 |
17 | rs749079480 |
0.0822 | -0.908 | 0.001 | N | 0.199 | 0.048 | 0.0846915920261 | gnomAD-4.0.0 | 1.59204E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8595E-06 | 0 | 0 |
| S/Y | 26006 |
Fn3-77 |
17 | None | 0.1199 | None | None | N | 0.423 | 0.222 | 0.42130639912 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 1.94099E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 26104 |
Fn3-78 |
17 | None | 0.1746 | None | 0.27 | N | 0.357 | 0.197 | 0.287603790349 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/P | 26699 |
Fn3-82 |
17 | rs1444605407 |
0.9775 | -0.637 | 0.997 | D | 0.791 | 0.576 | 0.359357374593 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/P | 26699 |
Fn3-82 |
17 | rs1444605407 |
0.9775 | -0.637 | 0.997 | D | 0.791 | 0.576 | 0.359357374593 | gnomAD-4.0.0 | 3.1838E-06 | None | None | None | None | N | None | 0 | 2.28728E-05 | None | 0 | 0 | None | 0 | 0 | 2.85956E-06 | 0 | 0 |
| S/G | 26796 |
Fn3-83 |
17 | None | 0.1829 | None | 0.757 | N | 0.441 | 0.331 | 0.322510055762 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 26796 |
Fn3-83 |
17 | None | 0.3309 | None | 0.324 | N | 0.489 | 0.299 | 0.265929055128 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/R | 26796 |
Fn3-83 |
17 | rs1651639361 |
0.7365 | None | 0.982 | N | 0.585 | 0.489 | 0.435915822735 | gnomAD-4.0.0 | 6.84292E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99586E-07 | 0 | 0 |
| S/T | 26796 |
Fn3-83 |
17 | rs1296203186 |
0.0815 | None | 0.001 | N | 0.115 | 0.135 | 0.203808441222 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/T | 26796 |
Fn3-83 |
17 | rs1296203186 |
0.0815 | None | 0.001 | N | 0.115 | 0.135 | 0.203808441222 | gnomAD-4.0.0 | 1.82703E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.04843E-05 | 0 | 3.40321E-05 |
| F/I | 26989 |
Fn3-84 |
18 | rs1348393968 |
0.3204 | None | 0.324 | N | 0.49 | 0.229 | 0.339555952218 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| F/S | 26989 |
Fn3-84 |
18 | rs1351288093 |
0.1654 | None | 0.006 | N | 0.398 | 0.193 | 0.325533332567 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88184E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 26989 |
Fn3-84 |
18 | rs1351288093 |
0.1654 | None | 0.006 | N | 0.398 | 0.193 | 0.325533332567 | gnomAD-4.0.0 | 2.56344E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.09366E-05 | 0 | None | 0 | 0 | 0 | 1.34095E-05 | 0 |
| N/K | 27186 |
Fn3-86 |
17 | None | 0.2584 | None | 0.012 | N | 0.314 | 0.074 | 0.0401082797425 | gnomAD-4.0.0 | 2.05308E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69861E-06 | 0 | 0 |
| N/S | 27186 |
Fn3-86 |
17 | rs368933290 |
0.0513 | None | None | N | 0.061 | 0.132 | None | gnomAD-4.0.0 | 1.59208E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85901E-06 | 0 | 0 |
| S/Y | 27485 |
Fn3-88 |
17 | None | 0.456 | None | 0.99 | N | 0.759 | 0.463 | 0.738581242654 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/L | 27782 |
Fn3-90 |
17 | rs769862471 |
0.1399 | -0.29 | 0.221 | D | 0.535 | 0.337 | 0.511390160789 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| S/L | 27782 |
Fn3-90 |
17 | rs769862471 |
0.1399 | -0.29 | 0.221 | D | 0.535 | 0.337 | 0.511390160789 | gnomAD-4.0.0 | 1.59248E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85941E-06 | 0 | 0 |
| S/P | 27782 |
Fn3-90 |
17 | None | 0.9816 | None | 0.974 | D | 0.757 | 0.422 | 0.405700215632 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| T/I | 27879 |
Fn3-91 |
17 | None | 0.5229 | None | 0.984 | N | 0.684 | 0.317 | 0.414930877219 | gnomAD-4.0.0 | 2.05367E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69889E-06 | 0 | 0 |
| S/N | 28071 |
Fn3-92 |
17 | rs1489303376 |
0.079 | -1.369 | None | N | 0.139 | 0.203 | 0.0401082797425 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| S/R | 28071 |
Fn3-92 |
17 | rs1169451357 |
0.6807 | -0.898 | 0.055 | N | 0.723 | 0.28 | 0.206339911435 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| S/R | 28071 |
Fn3-92 |
17 | rs1169451357 |
0.6807 | -0.898 | 0.055 | N | 0.723 | 0.28 | 0.206339911435 | gnomAD-4.0.0 | 1.59194E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85881E-06 | 0 | 0 |
| T/A | 28170 |
Fn3-93 |
17 | rs1703689855 |
0.072 | None | 0.08 | N | 0.316 | 0.082 | 0.149567049428 | gnomAD-4.0.0 | 1.59467E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86344E-06 | 0 | 0 |
| S/A | 28268 |
Fn3-94 |
17 | None | 0.1008 | None | 0.76 | N | 0.399 | 0.326 | 0.314417295294 | gnomAD-4.0.0 | 1.59116E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85804E-06 | 0 | 0 |
| S/L | 28268 |
Fn3-94 |
17 | None | 0.1635 | None | 0.885 | N | 0.653 | 0.398 | 0.65374614097 | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| S/C | 28566 |
Fn3-96 |
17 | None | 0.0801 | None | 0.78 | N | 0.681 | 0.2 | 0.266385636622 | gnomAD-4.0.0 | 6.84278E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99478E-07 | 0 | 0 |
| S/F | 28566 |
Fn3-96 |
17 | rs267599031 |
0.1035 | -0.981 | None | N | 0.441 | 0.176 | 0.288352970974 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| S/F | 28566 |
Fn3-96 |
17 | rs267599031 |
0.1035 | -0.981 | None | N | 0.441 | 0.176 | 0.288352970974 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/F | 28566 |
Fn3-96 |
17 | rs267599031 |
0.1035 | -0.981 | None | N | 0.441 | 0.176 | 0.288352970974 | gnomAD-4.0.0 | 1.17761E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52573E-05 | 0 | 1.60159E-05 |
| S/A | 28861 |
Fn3-98 |
17 | rs772173518 |
0.1087 | -0.726 | 0.098 | D | 0.428 | 0.103 | None | gnomAD-2.1.1 | 6.79E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 3.60346E-04 | 7.04E-05 | 0 |
| S/A | 28861 |
Fn3-98 |
17 | rs772173518 |
0.1087 | -0.726 | 0.098 | D | 0.428 | 0.103 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.45E-05 | 0 | 7.35E-05 | 0 | 0 |
| S/A | 28861 |
Fn3-98 |
17 | rs772173518 |
0.1087 | -0.726 | 0.098 | D | 0.428 | 0.103 | None | gnomAD-4.0.0 | 4.3572E-05 | None | None | None | None | N | None | 0 | 1.69549E-05 | None | 0 | 0 | None | 3.13982E-04 | 0 | 2.87211E-05 | 0 | 2.84414E-05 |
| S/G | 28958 |
Fn3-99 |
17 | None | 0.1245 | None | 1.0 | N | 0.509 | 0.478 | 0.360163838653 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 28958 |
Fn3-99 |
17 | rs199639729 |
0.1979 | -1.002 | 0.994 | N | 0.562 | 0.351 | None | gnomAD-2.1.1 | 4.66E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 4E-05 | 8.64E-05 | 0 |
| S/N | 28958 |
Fn3-99 |
17 | rs199639729 |
0.1979 | -1.002 | 0.994 | N | 0.562 | 0.351 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| S/N | 28958 |
Fn3-99 |
17 | rs199639729 |
0.1979 | -1.002 | 0.994 | N | 0.562 | 0.351 | None | gnomAD-4.0.0 | 5.63955E-05 | None | None | None | None | N | None | 1.33451E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.62848E-05 | 0 | 0 |
| S/R | 29154 |
Fn3-100 |
18 | rs766960470 |
0.8737 | -0.714 | 1.0 | N | 0.837 | 0.586 | 0.390060412749 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/R | 29154 |
Fn3-100 |
18 | rs766960470 |
0.8737 | -0.714 | 1.0 | N | 0.837 | 0.586 | 0.390060412749 | gnomAD-4.0.0 | 1.59157E-06 | None | None | None | None | N | None | 5.65163E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 29253 |
Fn3-101 |
17 | rs757300589 |
0.1678 | -1.206 | 0.959 | N | 0.57 | 0.34 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 3.56E-05 | 0 |
| S/N | 29253 |
Fn3-101 |
17 | rs757300589 |
0.1678 | -1.206 | 0.959 | N | 0.57 | 0.34 | None | gnomAD-3.1.2 | 6.57E-05 | None | None | None | None | N | None | 0 | 4.57995E-04 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 4.78469E-04 |
| S/N | 29253 |
Fn3-101 |
17 | rs757300589 |
0.1678 | -1.206 | 0.959 | N | 0.57 | 0.34 | None | gnomAD-4.0.0 | 2.54058E-05 | None | None | None | None | N | None | 0 | 1.99973E-04 | None | 0 | 0 | None | 0 | 0 | 2.37315E-05 | 0 | 1.60113E-05 |
| K/M | 29550 |
Fn3-103 |
18 | rs750362797 |
0.6621 | -0.091 | 0.999 | N | 0.565 | 0.482 | 0.353125101423 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| K/M | 29550 |
Fn3-103 |
18 | rs750362797 |
0.6621 | -0.091 | 0.999 | N | 0.565 | 0.482 | 0.353125101423 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/M | 29550 |
Fn3-103 |
18 | rs750362797 |
0.6621 | -0.091 | 0.999 | N | 0.565 | 0.482 | 0.353125101423 | gnomAD-4.0.0 | 1.85893E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.5427E-06 | 0 | 0 |
| K/N | 29550 |
Fn3-103 |
18 | rs778800874 |
0.7777 | -0.897 | 0.061 | N | 0.197 | 0.082 | 0.151104730317 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| K/N | 29550 |
Fn3-103 |
18 | rs778800874 |
0.7777 | -0.897 | 0.061 | N | 0.197 | 0.082 | 0.151104730317 | gnomAD-4.0.0 | 1.36834E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79886E-06 | 0 | 0 |
| S/L | 29649 |
Fn3-104 |
17 | rs764695663 |
0.1608 | 0.356 | 0.859 | D | 0.651 | 0.48 | 0.703810458386 | gnomAD-2.1.1 | 5.76E-05 | None | None | None | None | N | None | 0 | 2.07088E-04 | None | 0 | 0 | None | 6.84E-05 | None | 0 | 2.73E-05 | 3.39328E-04 |
| S/L | 29649 |
Fn3-104 |
17 | rs764695663 |
0.1608 | 0.356 | 0.859 | D | 0.651 | 0.48 | 0.703810458386 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 1.30993E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 29649 |
Fn3-104 |
17 | rs764695663 |
0.1608 | 0.356 | 0.859 | D | 0.651 | 0.48 | 0.703810458386 | gnomAD-4.0.0 | 1.98743E-05 | None | None | None | None | N | None | 1.34048E-05 | 1.51612E-04 | None | 0 | 2.22955E-05 | None | 0 | 0 | 1.0181E-05 | 3.33267E-05 | 9.62896E-05 |
| T/I | 29949 |
Fn3-106 |
17 | rs1284316750 |
0.171 | -0.199 | 0.81 | N | 0.619 | 0.244 | 0.458374381611 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/I | 29949 |
Fn3-106 |
17 | rs1284316750 |
0.171 | -0.199 | 0.81 | N | 0.619 | 0.244 | 0.458374381611 | gnomAD-4.0.0 | 1.36982E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79924E-06 | 0 | 0 |
| S/C | 30046 |
Fn3-107 |
17 | rs1400410632 |
0.1711 | -1.15 | 1.0 | N | 0.761 | 0.478 | 0.693281465932 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| S/C | 30046 |
Fn3-107 |
17 | rs1400410632 |
0.1711 | -1.15 | 1.0 | N | 0.761 | 0.478 | 0.693281465932 | gnomAD-4.0.0 | 6.84174E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52003E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/Y | 30046 |
Fn3-107 |
17 | None | 0.3598 | None | 1.0 | N | 0.826 | 0.432 | 0.812780994167 | gnomAD-4.0.0 | 6.84174E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65634E-05 |
| S/N | 30241 |
Fn3-108 |
18 | None | 0.305 | None | 0.999 | N | 0.613 | 0.326 | 0.249502417897 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| G/C | 30340 |
Fn3-109 |
17 | rs758970884 |
0.3205 | -1.902 | 1.0 | N | 0.781 | 0.474 | 0.6507782609 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/A | 30438 |
Fn3-110 |
17 | None | 0.1535 | None | 0.835 | N | 0.387 | 0.143 | 0.215869574891 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 3.66327E-05 |
| S/N | 30735 |
Fn3-112 |
17 | rs1225964281 |
0.2951 | None | 0.994 | N | 0.497 | 0.374 | 0.318828661733 | gnomAD-4.0.0 | 1.36972E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80069E-06 | 0 | 0 |
| T/S | 30837 |
Fn3-113 |
17 | None | 0.0826 | None | 0.014 | N | 0.187 | 0.068 | 0.104622674875 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/C | 31032 |
Fn3-114 |
17 | None | 0.0869 | None | 1.0 | N | 0.743 | 0.487 | 0.526892676112 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/F | 31032 |
Fn3-114 |
17 | rs1698112765 |
0.1464 | None | 0.998 | N | 0.781 | 0.503 | 0.525922550829 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 31032 |
Fn3-114 |
17 | rs1698112765 |
0.1464 | None | 0.998 | N | 0.781 | 0.503 | 0.525922550829 | gnomAD-4.0.0 | 6.57125E-06 | None | None | None | None | N | None | 2.41243E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 31129 |
Fn3-115 |
17 | None | 0.1994 | None | 0.896 | N | 0.654 | 0.372 | 0.635364320139 | gnomAD-4.0.0 | 2.73673E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59779E-06 | 0 | 0 |
| S/L | 31325 |
Fn3-116 |
18 | rs143679526 |
0.3028 | -0.065 | 1.0 | N | 0.772 | 0.49 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 1.29182E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| S/L | 31325 |
Fn3-116 |
18 | rs143679526 |
0.3028 | -0.065 | 1.0 | N | 0.772 | 0.49 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06954E-04 | 0 |
| S/L | 31325 |
Fn3-116 |
18 | rs143679526 |
0.3028 | -0.065 | 1.0 | N | 0.772 | 0.49 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| S/L | 31325 |
Fn3-116 |
18 | rs143679526 |
0.3028 | -0.065 | 1.0 | N | 0.772 | 0.49 | None | gnomAD-4.0.0 | 8.675E-06 | None | None | None | None | N | None | 6.66631E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78076E-06 | 1.09786E-05 | 0 |
| S/T | 31325 |
Fn3-116 |
18 | None | 0.1409 | None | 0.999 | N | 0.487 | 0.363 | 0.392855499163 | gnomAD-4.0.0 | 1.59105E-06 | None | None | None | None | N | None | 0 | 2.28655E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/P | 31424 |
Fn3-117 |
17 | None | 0.9722 | None | 0.497 | N | 0.757 | 0.269 | 0.405422107966 | gnomAD-4.0.0 | 1.59158E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43303E-05 | 0 |
| A/V | 31424 |
Fn3-117 |
17 | rs1178719189 |
0.1221 | None | 0.009 | N | 0.345 | 0.17 | 0.362160248664 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| T/A | 31522 |
Fn3-118 |
17 | rs1697400184 |
0.1205 | None | 0.64 | N | 0.401 | 0.12 | 0.258283824007 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| T/I | 31522 |
Fn3-118 |
17 | rs1360429703 |
0.7488 | -0.093 | 0.984 | N | 0.687 | 0.466 | 0.527759996296 | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 0 | 2.95E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 31522 |
Fn3-118 |
17 | rs1360429703 |
0.7488 | -0.093 | 0.984 | N | 0.687 | 0.466 | 0.527759996296 | gnomAD-4.0.0 | 1.6296E-06 | None | None | None | None | N | None | 0 | 2.31289E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 31724 |
Fn3-119 |
17 | rs1322640877 |
0.3846 | -1.035 | 1.0 | N | 0.692 | 0.408 | 0.214338557667 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| K/Q | 31724 |
Fn3-119 |
17 | rs1322640877 |
0.3846 | -1.035 | 1.0 | N | 0.692 | 0.408 | 0.214338557667 | gnomAD-4.0.0 | 1.59222E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86017E-06 | 0 | 0 |
| H/R | 31823 |
Fn3-120 |
17 | rs794729539 |
0.3434 | -1.034 | 0.999 | N | 0.451 | 0.278 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| H/R | 31823 |
Fn3-120 |
17 | rs794729539 |
0.3434 | -1.034 | 0.999 | N | 0.451 | 0.278 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| H/R | 31823 |
Fn3-120 |
17 | rs794729539 |
0.3434 | -1.034 | 0.999 | N | 0.451 | 0.278 | None | gnomAD-4.0.0 | 2.04499E-05 | None | None | None | None | N | None | 1.33472E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54292E-05 | 0 | 3.20225E-05 |
| S/R | 31925 |
Fn3-121 |
17 | None | 0.918 | None | 1.0 | N | 0.833 | 0.537 | 0.498896430806 | gnomAD-4.0.0 | 6.84393E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65684E-05 |
| S/C | 32121 |
Fn3-122 |
17 | rs1258025777 |
0.1115 | -1.25 | 1.0 | N | 0.797 | 0.489 | 0.53046153047 | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.64E-05 | None | 0 | None | 0 | 0 | 0 |
| S/C | 32121 |
Fn3-122 |
17 | rs1258025777 |
0.1115 | -1.25 | 1.0 | N | 0.797 | 0.489 | 0.53046153047 | gnomAD-4.0.0 | 1.61639E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77886E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 32121 |
Fn3-122 |
17 | None | 0.2273 | None | 1.0 | N | 0.867 | 0.494 | 0.679310148475 | gnomAD-4.0.0 | 1.61639E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43406E-05 | 0 |
| S/L | 32416 |
Fn3-124 |
18 | rs377412567 |
0.2304 | -0.251 | 0.811 | D | 0.663 | 0.377 | None | gnomAD-2.1.1 | 6.09E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.17873E-04 | 1.40964E-04 |
| S/L | 32416 |
Fn3-124 |
18 | rs377412567 |
0.2304 | -0.251 | 0.811 | D | 0.663 | 0.377 | None | gnomAD-3.1.2 | 8.54E-05 | None | None | None | None | N | None | 4.83E-05 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47024E-04 | 0 | 0 |
| S/L | 32416 |
Fn3-124 |
18 | rs377412567 |
0.2304 | -0.251 | 0.811 | D | 0.663 | 0.377 | None | gnomAD-4.0.0 | 1.48897E-04 | None | None | None | None | N | None | 2.6708E-05 | 1.6675E-05 | None | 0 | 0 | None | 0 | 0 | 1.93508E-04 | 0 | 1.44254E-04 |
| G/A | 32515 |
Fn3-125 |
17 | None | 0.1671 | None | 1.0 | N | 0.615 | 0.407 | 0.247872288689 | gnomAD-4.0.0 | 1.59417E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86305E-06 | 0 | 0 |
| S/T | 32616 |
Fn3-126 |
17 | None | 0.1278 | None | 0.999 | N | 0.489 | 0.322 | 0.402614778071 | gnomAD-4.0.0 | 3.60098E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.93752E-06 | 0 | 0 |
| S/P | 32812 |
Fn3-127 |
18 | None | 0.9937 | None | 0.999 | D | 0.773 | 0.541 | 0.477685322099 | gnomAD-4.0.0 | 8.40225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.18751E-06 | 0 | 0 |
| S/F | 32913 |
Fn3-128 |
18 | None | 0.5168 | None | 0.988 | N | 0.608 | 0.484 | 0.775252716994 | gnomAD-4.0.0 | 1.36845E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79898E-06 | 0 | 0 |
| S/Y | 32913 |
Fn3-128 |
18 | rs749035234 |
0.5208 | -0.847 | 0.996 | N | 0.609 | 0.463 | 0.758241242785 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/Y | 32913 |
Fn3-128 |
18 | rs749035234 |
0.5208 | -0.847 | 0.996 | N | 0.609 | 0.463 | 0.758241242785 | gnomAD-4.0.0 | 6.84224E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51965E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 33014 |
Fn3-129 |
17 | None | 0.0916 | None | 0.994 | N | 0.461 | 0.281 | 0.3349148499 | gnomAD-4.0.0 | 2.05314E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.97034E-05 |
| S/C | 33408 |
Fn3-131 |
17 | rs1268223494 |
0.1806 | -0.995 | 1.0 | N | 0.814 | 0.521 | 0.554920031903 | gnomAD-2.1.1 | 5.51E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.13E-05 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.