Structural position:
- Domain Type: Fn3
- Aligned Position: 2
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/L | 15658 |
Fn3-1 |
2 | rs794729440 |
0.986 | None | 1.0 | D | 0.799 | 0.77 | 0.7654171 | gnomAD-4.0.0 | 1.5971E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86518E-06 | 0 | 0 |
| P/S | 15860 |
Fn3-3 |
2 | rs754280245 |
0.9709 | -2.506 | 1.0 | D | 0.789 | 0.621 | None | gnomAD-2.1.1 | 2.34E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.99E-05 | 0 |
| P/S | 15860 |
Fn3-3 |
2 | rs754280245 |
0.9709 | -2.506 | 1.0 | D | 0.789 | 0.621 | None | gnomAD-4.0.0 | 1.33754E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.34751E-05 | 0 | 0 |
| P/L | 16056 |
Fn3-4 |
2 | rs752993848 |
0.9781 | -0.247 | 1.0 | D | 0.822 | 0.764 | None | gnomAD-2.1.1 | 8.25E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 1.60385E-04 | 1.4924E-04 | 0 |
| P/L | 16056 |
Fn3-4 |
2 | rs752993848 |
0.9781 | -0.247 | 1.0 | D | 0.822 | 0.764 | None | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.45E-05 | 0 | 0 | 0 | 0 |
| P/L | 16056 |
Fn3-4 |
2 | rs752993848 |
0.9781 | -0.247 | 1.0 | D | 0.822 | 0.764 | None | gnomAD-4.0.0 | 2.29556E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 7.81959E-05 | 0 | 2.37508E-05 | 0 | 6.41519E-05 |
| P/S | 16056 |
Fn3-4 |
2 | rs2057390140 |
0.9845 | None | 1.0 | D | 0.733 | 0.818 | 0.7595363 | gnomAD-4.0.0 | 1.59508E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43571E-05 | 0 |
| P/S | 16156 |
Fn3-5 |
2 | rs373195648 |
0.9932 | -2.264 | 0.911 | D | 0.421 | 0.467 | None | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| P/S | 16156 |
Fn3-5 |
2 | rs373195648 |
0.9932 | -2.264 | 0.911 | D | 0.421 | 0.467 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 16156 |
Fn3-5 |
2 | rs373195648 |
0.9932 | -2.264 | 0.911 | D | 0.421 | 0.467 | None | gnomAD-4.0.0 | 1.86202E-05 | None | None | None | None | N | None | 1.33811E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.46131E-05 | 0 | 0 |
| P/T | 16352 |
Fn3-6 |
2 | rs2056897383 |
0.9941 | None | 1.0 | D | 0.749 | 0.786 | 0.7598812 | gnomAD-4.0.0 | 1.59449E-06 | None | None | None | None | N | None | 0 | 2.29253E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 16451 |
Fn3-7 |
2 | None | 0.9902 | None | 1.0 | D | 0.83 | 0.491 | 0.76924914 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 16451 |
Fn3-7 |
2 | rs1171196645 |
0.9935 | None | 1.0 | D | 0.8 | 0.471 | 0.5044803 | gnomAD-4.0.0 | 1.60592E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.88108E-06 | 0 | 0 |
| P/S | 16552 |
Fn3-8 |
2 | rs2056637064 |
0.9801 | None | 1.0 | D | 0.764 | 0.809 | 0.7438272 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 16552 |
Fn3-8 |
2 | rs2056637064 |
0.9801 | None | 1.0 | D | 0.764 | 0.809 | 0.7438272 | gnomAD-4.0.0 | 6.5812E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47171E-05 | 0 | 0 |
| P/A | 16752 |
Fn3-10 |
2 | rs938347047 |
0.8777 | -1.437 | 0.999 | D | 0.837 | 0.528 | 0.75191253 | gnomAD-2.1.1 | 8.27E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.09E-06 | 1.70126E-04 |
| P/A | 16752 |
Fn3-10 |
2 | rs938347047 |
0.8777 | -1.437 | 0.999 | D | 0.837 | 0.528 | 0.75191253 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 1.96773E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| P/A | 16752 |
Fn3-10 |
2 | rs938347047 |
0.8777 | -1.437 | 0.999 | D | 0.837 | 0.528 | 0.75191253 | gnomAD-4.0.0 | 9.94775E-06 | None | None | None | None | N | None | 4.02404E-05 | 5.08578E-05 | None | 0 | 0 | None | 0 | 0 | 5.94257E-06 | 0 | 4.82145E-05 |
| P/R | 16752 |
Fn3-10 |
2 | rs2056443749 |
0.996 | None | 1.0 | D | 0.861 | 0.585 | 0.8351891 | gnomAD-4.0.0 | 1.71639E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.25213E-05 | 0 | 0 |
| P/L | 16853 |
Fn3-11 |
2 | rs373517736 |
0.9785 | None | 1.0 | D | 0.822 | 0.474 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/A | 17048 |
Fn3-12 |
2 | None | 0.9228 | None | 1.0 | D | 0.745 | 0.83 | 0.72593683 | gnomAD-4.0.0 | 6.86911E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00742E-07 | 0 | 0 |
| P/L | 17048 |
Fn3-12 |
2 | rs747934823 |
0.9824 | -1.127 | 1.0 | D | 0.792 | 0.812 | 0.8736686 | gnomAD-2.1.1 | 1.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.44E-05 | None | 0 | 1.8E-05 | 0 |
| P/L | 17048 |
Fn3-12 |
2 | rs747934823 |
0.9824 | -1.127 | 1.0 | D | 0.792 | 0.812 | 0.8736686 | gnomAD-4.0.0 | 3.21117E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87071E-06 | 1.4661E-05 | 0 |
| P/R | 17048 |
Fn3-12 |
2 | rs747934823 |
0.9972 | None | 1.0 | D | 0.816 | 0.82 | 0.78515714 | gnomAD-4.0.0 | 1.60558E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4661E-05 | 0 |
| P/S | 17048 |
Fn3-12 |
2 | rs769444545 |
0.9909 | -2.848 | 1.0 | D | 0.785 | 0.838 | None | gnomAD-2.1.1 | 7.27E-06 | None | None | None | None | N | None | 4.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.9E-06 | 0 |
| P/S | 17048 |
Fn3-12 |
2 | rs769444545 |
0.9909 | -2.848 | 1.0 | D | 0.785 | 0.838 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 17048 |
Fn3-12 |
2 | rs769444545 |
0.9909 | -2.848 | 1.0 | D | 0.785 | 0.838 | None | gnomAD-4.0.0 | 4.35393E-06 | None | None | None | None | N | None | 1.34419E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.24401E-06 | 0 | 1.60823E-05 |
| P/A | 17148 |
Fn3-13 |
2 | None | 0.9203 | None | 0.999 | D | 0.827 | 0.51 | 0.58077055 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| P/R | 17148 |
Fn3-13 |
2 | rs2154198776 |
0.9982 | None | 1.0 | D | 0.835 | 0.516 | 0.6519314 | gnomAD-4.0.0 | 3.42732E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.50133E-06 | 0 | 0 |
| P/S | 17148 |
Fn3-13 |
2 | rs727504193 |
0.9932 | None | 1.0 | D | 0.775 | 0.519 | 0.57265735 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| P/A | 17370 |
Fn3-14 |
2 | None | 0.9348 | None | 0.999 | D | 0.828 | 0.771 | 0.7385889 | gnomAD-4.0.0 | 6.86945E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00139E-07 | 0 | 0 |
| P/L | 17370 |
Fn3-14 |
2 | rs773071032 |
0.9892 | -0.48 | 1.0 | D | 0.824 | 0.803 | 0.8773797 | gnomAD-2.1.1 | 1.82E-05 | None | None | None | None | N | None | 4.15E-05 | 2.85E-05 | None | 0 | 0 | None | 0 | None | 0 | 2.36E-05 | 0 |
| P/L | 17370 |
Fn3-14 |
2 | rs773071032 |
0.9892 | -0.48 | 1.0 | D | 0.824 | 0.803 | 0.8773797 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 17370 |
Fn3-14 |
2 | rs773071032 |
0.9892 | -0.48 | 1.0 | D | 0.824 | 0.803 | 0.8773797 | gnomAD-4.0.0 | 1.05754E-05 | None | None | None | None | N | None | 1.34063E-05 | 3.35278E-05 | None | 0 | 2.23754E-05 | None | 0 | 0 | 8.48283E-06 | 1.10261E-05 | 3.21058E-05 |
| P/L | 17471 |
Fn3-15 |
2 | None | 0.977 | None | 1.0 | D | 0.812 | 0.543 | 0.73225564 | gnomAD-4.0.0 | 6.99387E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.09809E-07 | 0 | 0 |
| P/S | 17471 |
Fn3-15 |
2 | rs551867239 |
0.9804 | -2.239 | 1.0 | D | 0.741 | 0.567 | 0.5309483 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| P/S | 17471 |
Fn3-15 |
2 | rs551867239 |
0.9804 | -2.239 | 1.0 | D | 0.741 | 0.567 | 0.5309483 | gnomAD-2.1.1 | 1.41E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.24616E-04 | None | 0 | 0 | 0 |
| P/S | 17471 |
Fn3-15 |
2 | rs551867239 |
0.9804 | -2.239 | 1.0 | D | 0.741 | 0.567 | 0.5309483 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| P/S | 17471 |
Fn3-15 |
2 | rs551867239 |
0.9804 | -2.239 | 1.0 | D | 0.741 | 0.567 | 0.5309483 | gnomAD-4.0.0 | 4.42579E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.56948E-07 | 4.69473E-05 | 3.26915E-05 |
| P/H | 17570 |
Fn3-16 |
2 | None | 0.357 | None | 1.0 | N | 0.817 | 0.403 | 0.4247895 | gnomAD-4.0.0 | 1.59588E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43472E-05 | 0 |
| P/L | 17570 |
Fn3-16 |
2 | rs2055350149 |
0.1495 | None | 1.0 | N | 0.832 | 0.401 | 0.50454116 | gnomAD-4.0.0 | 3.19178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59816E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 17765 |
Fn3-17 |
2 | rs1298494593 |
0.9965 | -0.616 | 1.0 | D | 0.891 | 0.708 | 0.74552584 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| P/S | 17765 |
Fn3-17 |
2 | rs1298494593 |
0.9965 | -0.616 | 1.0 | D | 0.891 | 0.708 | 0.74552584 | gnomAD-4.0.0 | 1.59458E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86241E-06 | 0 | 0 |
| P/S | 17863 |
Fn3-18 |
2 | rs779017618 |
0.9896 | -2.297 | 1.0 | D | 0.77 | 0.552 | 0.49870506 | gnomAD-2.1.1 | 1.28E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
| P/S | 17863 |
Fn3-18 |
2 | rs779017618 |
0.9896 | -2.297 | 1.0 | D | 0.77 | 0.552 | 0.49870506 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/S | 17863 |
Fn3-18 |
2 | rs779017618 |
0.9896 | -2.297 | 1.0 | D | 0.77 | 0.552 | 0.49870506 | gnomAD-4.0.0 | 4.33387E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.07942E-06 | 0 | 0 |
| P/A | 18066 |
Fn3-19 |
2 | None | 0.9788 | None | 0.999 | D | 0.799 | 0.75 | 0.76128745 | gnomAD-4.0.0 | 1.59712E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86771E-06 | 0 | 0 |
| P/A | 18273 |
Fn3-21 |
2 | None | 0.6313 | None | 0.914 | D | 0.707 | 0.628 | 0.6830934 | gnomAD-4.0.0 | 7.41087E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.43524E-07 | 0 | 0 |
| P/L | 18273 |
Fn3-21 |
2 | rs201035511 |
0.9668 | -0.667 | 0.995 | D | 0.782 | 0.689 | None | gnomAD-2.1.1 | 3.99176E-04 | None | None | None | None | N | None | 5.73E-05 | 2.19138E-04 | None | 9.31446E-04 | 0 | None | 0 | None | 0 | 7.3091E-04 | 4.68165E-04 |
| P/L | 18273 |
Fn3-21 |
2 | rs201035511 |
0.9668 | -0.667 | 0.995 | D | 0.782 | 0.689 | None | gnomAD-3.1.2 | 4.81124E-04 | None | None | None | None | N | None | 9.68E-05 | 1.97394E-04 | 0 | 1.44175E-03 | 3.90168E-04 | None | 9.49E-05 | 0 | 8.5387E-04 | 0 | 0 |
| P/L | 18273 |
Fn3-21 |
2 | rs201035511 |
0.9668 | -0.667 | 0.995 | D | 0.782 | 0.689 | None | gnomAD-4.0.0 | 6.30037E-04 | None | None | None | None | N | None | 8.48512E-05 | 2.63158E-04 | None | 9.02173E-04 | 4.84074E-05 | None | 1.01238E-04 | 3.53232E-04 | 7.77725E-04 | 0 | 3.45817E-04 |
| P/R | 18273 |
Fn3-21 |
2 | None | 0.9914 | None | 0.163 | D | 0.617 | 0.615 | 0.66630363 | gnomAD-4.0.0 | 7.40058E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.42488E-07 | 0 | 0 |
| P/S | 18580 |
Fn3-23 |
2 | rs528329600 |
0.9853 | -2.039 | 1.0 | N | 0.763 | 0.495 | 0.41921207 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| P/S | 18580 |
Fn3-23 |
2 | rs528329600 |
0.9853 | -2.039 | 1.0 | N | 0.763 | 0.495 | 0.41921207 | gnomAD-2.1.1 | 7.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 8.26867E-04 | None | 0 | 0 | 0 |
| P/S | 18580 |
Fn3-23 |
2 | rs528329600 |
0.9853 | -2.039 | 1.0 | N | 0.763 | 0.495 | 0.41921207 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.1425E-04 | 0 |
| P/S | 18580 |
Fn3-23 |
2 | rs528329600 |
0.9853 | -2.039 | 1.0 | N | 0.763 | 0.495 | 0.41921207 | gnomAD-4.0.0 | 6.87109E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.76429E-04 | 0 | 1.3097E-03 | 1.02194E-04 |
| P/L | 18785 |
Fn3-24 |
2 | None | 0.9824 | None | 1.0 | D | 0.851 | 0.811 | 0.88601935 | gnomAD-4.0.0 | 7.24949E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.30425E-07 | 0 | 0 |
| P/R | 18785 |
Fn3-24 |
2 | rs749655114 |
0.9924 | -1.047 | 1.0 | D | 0.867 | 0.835 | 0.8311906 | gnomAD-2.1.1 | 2.16E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.47E-05 | 0 |
| P/R | 18785 |
Fn3-24 |
2 | rs749655114 |
0.9924 | -1.047 | 1.0 | D | 0.867 | 0.835 | 0.8311906 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| P/R | 18785 |
Fn3-24 |
2 | rs749655114 |
0.9924 | -1.047 | 1.0 | D | 0.867 | 0.835 | 0.8311906 | gnomAD-4.0.0 | 1.37128E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.66265E-05 | 0 | 3.39766E-05 |
| P/R | 18885 |
Fn3-25 |
2 | rs780890752 |
0.9896 | -0.873 | 1.0 | D | 0.824 | 0.551 | None | gnomAD-2.1.1 | 1.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.1E-05 | 0 |
| P/R | 18885 |
Fn3-25 |
2 | rs780890752 |
0.9896 | -0.873 | 1.0 | D | 0.824 | 0.551 | None | gnomAD-4.0.0 | 7.89693E-06 | None | None | None | None | N | None | 6.58762E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.31383E-06 | 0 | 0 |
| P/S | 18885 |
Fn3-25 |
2 | rs747971851 |
0.9708 | -2.006 | 1.0 | D | 0.751 | 0.539 | 0.50118357 | gnomAD-2.1.1 | 1.03E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.95E-05 | None | 0 | 0 | 0 |
| P/S | 18885 |
Fn3-25 |
2 | rs747971851 |
0.9708 | -2.006 | 1.0 | D | 0.751 | 0.539 | 0.50118357 | gnomAD-3.1.2 | 6.6E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 18885 |
Fn3-25 |
2 | rs747971851 |
0.9708 | -2.006 | 1.0 | D | 0.751 | 0.539 | 0.50118357 | gnomAD-4.0.0 | 2.07683E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.9158E-05 | 1.14664E-04 | 1.6913E-05 |
| P/S | 19480 |
Fn3-29 |
2 | None | 0.9936 | None | 1.0 | D | 0.769 | 0.479 | 0.531532 | gnomAD-4.0.0 | 3.19982E-06 | None | None | None | None | N | None | 0 | 4.64188E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 19580 |
Fn3-30 |
2 | None | 0.9609 | None | 1.0 | D | 0.815 | 0.614 | 0.79649895 | gnomAD-4.0.0 | 1.60459E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86707E-06 | 0 | 0 |
| P/L | 19681 |
Fn3-31 |
2 | rs776257317 |
0.9655 | -0.502 | 1.0 | D | 0.828 | 0.473 | 0.71439564 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.34E-05 | None | 0 | 0 | 0 |
| P/L | 19681 |
Fn3-31 |
2 | rs776257317 |
0.9655 | -0.502 | 1.0 | D | 0.828 | 0.473 | 0.71439564 | gnomAD-4.0.0 | 1.59714E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44642E-05 | 0 |
| P/Q | 19681 |
Fn3-31 |
2 | rs776257317 |
0.9969 | None | 1.0 | D | 0.861 | 0.505 | 0.5891018 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 19681 |
Fn3-31 |
2 | rs776257317 |
0.9969 | None | 1.0 | D | 0.861 | 0.505 | 0.5891018 | gnomAD-4.0.0 | 2.57042E-06 | None | None | None | None | N | None | 3.39916E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 19878 |
Fn3-32 |
2 | rs752854931 |
0.99 | None | 1.0 | D | 0.743 | 0.726 | 0.7399269 | gnomAD-4.0.0 | 1.60234E-06 | None | None | None | None | N | None | 0 | 2.33165E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 19878 |
Fn3-32 |
2 | rs752854931 |
0.9837 | -2.23 | 1.0 | D | 0.753 | 0.729 | 0.7585849 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 0 | 3E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 19878 |
Fn3-32 |
2 | rs752854931 |
0.9837 | -2.23 | 1.0 | D | 0.753 | 0.729 | 0.7585849 | gnomAD-4.0.0 | 3.20467E-06 | None | None | None | None | N | None | 0 | 2.33165E-05 | None | 0 | 2.79673E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 19978 |
Fn3-33 |
2 | rs1366471902 |
0.6156 | -2.178 | 0.999 | D | 0.813 | 0.479 | 0.54613155 | gnomAD-2.1.1 | 8.26E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.81E-05 | 0 |
| P/A | 19978 |
Fn3-33 |
2 | rs1366471902 |
0.6156 | -2.178 | 0.999 | D | 0.813 | 0.479 | 0.54613155 | gnomAD-4.0.0 | 3.21447E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.74303E-06 | 0 | 0 |
| P/L | 19978 |
Fn3-33 |
2 | rs1303172310 |
0.9536 | -0.908 | 1.0 | D | 0.855 | 0.477 | 0.77226526 | gnomAD-2.1.1 | 4.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.05E-06 | 0 |
| P/L | 19978 |
Fn3-33 |
2 | rs1303172310 |
0.9536 | -0.908 | 1.0 | D | 0.855 | 0.477 | 0.77226526 | gnomAD-4.0.0 | 4.81012E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.3055E-06 | 0 | 0 |
| P/L | 20272 |
Fn3-35 |
2 | rs760277470 |
0.9406 | -0.454 | 1.0 | D | 0.814 | 0.477 | 0.7332232 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.66E-05 | 2.68E-05 | 0 |
| P/L | 20272 |
Fn3-35 |
2 | rs760277470 |
0.9406 | -0.454 | 1.0 | D | 0.814 | 0.477 | 0.7332232 | gnomAD-4.0.0 | 4.7937E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.74756E-05 | 0 | 4.50115E-06 | 0 | 0 |
| P/S | 20272 |
Fn3-35 |
2 | rs945591043 |
0.9422 | None | 1.0 | D | 0.769 | 0.471 | 0.5611408 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 20272 |
Fn3-35 |
2 | rs945591043 |
0.9422 | None | 1.0 | D | 0.769 | 0.471 | 0.5611408 | gnomAD-4.0.0 | 1.31517E-05 | None | None | None | None | N | None | 4.82742E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 20570 |
Fn3-37 |
2 | rs769184808 |
0.9672 | -2.099 | 1.0 | D | 0.745 | 0.72 | 0.7732167 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| P/A | 20570 |
Fn3-37 |
2 | rs769184808 |
0.9672 | -2.099 | 1.0 | D | 0.745 | 0.72 | 0.7732167 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/A | 20570 |
Fn3-37 |
2 | rs769184808 |
0.9672 | -2.099 | 1.0 | D | 0.745 | 0.72 | 0.7732167 | gnomAD-4.0.0 | 6.81924E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.47447E-05 | None | 0 | 0 | 7.63024E-06 | 0 | 0 |
| P/R | 20669 |
Fn3-38 |
2 | rs1025235862 |
0.9972 | None | 1.0 | D | 0.87 | 0.56 | 0.5900793 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/R | 20669 |
Fn3-38 |
2 | rs1025235862 |
0.9972 | None | 1.0 | D | 0.87 | 0.56 | 0.5900793 | gnomAD-4.0.0 | 3.09905E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39095E-06 | 1.09806E-05 | 0 |
| P/S | 20669 |
Fn3-38 |
2 | rs1553641246 |
0.9961 | None | 1.0 | N | 0.788 | 0.52 | 0.50231725 | gnomAD-4.0.0 | 3.18347E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71873E-06 | 0 | 0 |
| P/T | 20865 |
Fn3-39 |
2 | rs757101265 |
0.9918 | -2.25 | 1.0 | D | 0.769 | 0.692 | 0.8084036 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.28803E-04 | None | 0 | 0 | 0 |
| P/T | 20865 |
Fn3-39 |
2 | rs757101265 |
0.9918 | -2.25 | 1.0 | D | 0.769 | 0.692 | 0.8084036 | gnomAD-4.0.0 | 1.84847E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99556E-07 | 3.0147E-04 | 0 |
| P/H | 20964 |
Fn3-40 |
2 | rs548460016 |
0.9962 | -0.064 | 1.0 | D | 0.838 | 0.479 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| P/H | 20964 |
Fn3-40 |
2 | rs548460016 |
0.9962 | -0.064 | 1.0 | D | 0.838 | 0.479 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| P/H | 20964 |
Fn3-40 |
2 | rs548460016 |
0.9962 | -0.064 | 1.0 | D | 0.838 | 0.479 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/H | 20964 |
Fn3-40 |
2 | rs548460016 |
0.9962 | -0.064 | 1.0 | D | 0.838 | 0.479 | None | gnomAD-4.0.0 | 9.91724E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.27163E-05 | 0 | 1.60092E-05 |
| P/S | 20964 |
Fn3-40 |
2 | None | 0.964 | None | 1.0 | D | 0.795 | 0.478 | 0.51133156 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| P/A | 21065 |
Fn3-41 |
2 | None | 0.8119 | None | 0.999 | D | 0.849 | 0.683 | 0.71170974 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| P/L | 21065 |
Fn3-41 |
2 | None | 0.9823 | None | 1.0 | D | 0.863 | 0.723 | 0.8988848 | gnomAD-4.0.0 | 7.07237E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.21448E-07 | 0 | 0 |
| P/R | 21065 |
Fn3-41 |
2 | rs2049459670 |
0.9954 | None | 1.0 | D | 0.855 | 0.745 | 0.86675864 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 21065 |
Fn3-41 |
2 | rs2049459670 |
0.9954 | None | 1.0 | D | 0.855 | 0.745 | 0.86675864 | gnomAD-4.0.0 | 5.1085E-06 | None | None | None | None | N | None | 0 | 1.79527E-05 | None | 0 | 0 | None | 0 | 0 | 6.0699E-06 | 0 | 0 |
| P/L | 21267 |
Fn3-42 |
2 | rs200365508 |
0.9753 | -0.396 | 0.986 | D | 0.791 | 0.652 | None | gnomAD-2.1.1 | 1.11E-05 | None | None | None | None | N | None | 1.28899E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 21267 |
Fn3-42 |
2 | rs200365508 |
0.9753 | -0.396 | 0.986 | D | 0.791 | 0.652 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 2.17339E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 21267 |
Fn3-42 |
2 | rs200365508 |
0.9753 | -0.396 | 0.986 | D | 0.791 | 0.652 | None | gnomAD-4.0.0 | 8.70561E-06 | None | None | None | None | N | None | 1.87326E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 21367 |
Fn3-43 |
2 | rs754581725 |
0.9904 | -0.837 | 1.0 | D | 0.864 | 0.489 | None | gnomAD-2.1.1 | 2.87E-05 | None | None | None | None | N | None | 6.5E-05 | 1.49441E-04 | None | 0 | 0 | None | 0 | None | 0 | 9.02E-06 | 0 |
| P/L | 21367 |
Fn3-43 |
2 | rs754581725 |
0.9904 | -0.837 | 1.0 | D | 0.864 | 0.489 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 21367 |
Fn3-43 |
2 | rs754581725 |
0.9904 | -0.837 | 1.0 | D | 0.864 | 0.489 | None | gnomAD-4.0.0 | 8.70051E-06 | None | None | None | None | N | None | 2.68759E-05 | 1.19031E-04 | None | 0 | 0 | None | 0 | 1.65782E-04 | 2.54554E-06 | 1.1117E-05 | 0 |
| P/T | 21367 |
Fn3-43 |
2 | None | 0.9926 | None | 1.0 | D | 0.805 | 0.506 | 0.69979787 | gnomAD-4.0.0 | 6.86244E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00429E-07 | 0 | 0 |
| P/H | 21660 |
Fn3-45 |
2 | rs1037246417 |
0.9977 | -1.012 | 1.0 | D | 0.751 | 0.549 | 0.6010955 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| P/H | 21660 |
Fn3-45 |
2 | rs1037246417 |
0.9977 | -1.012 | 1.0 | D | 0.751 | 0.549 | 0.6010955 | gnomAD-4.0.0 | 4.79629E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.30305E-06 | 0 | 0 |
| P/T | 21660 |
Fn3-45 |
2 | rs2048516567 |
0.9822 | None | 1.0 | D | 0.756 | 0.525 | 0.52835864 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 21660 |
Fn3-45 |
2 | rs2048516567 |
0.9822 | None | 1.0 | D | 0.756 | 0.525 | 0.52835864 | gnomAD-4.0.0 | 6.57964E-06 | None | None | None | None | N | None | 2.41628E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 21758 |
Fn3-46 |
2 | None | 0.5853 | None | 0.856 | N | 0.549 | 0.256 | 0.43720734 | gnomAD-4.0.0 | 1.76645E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.12533E-06 | 0 | 0 |
| V/F | 21758 |
Fn3-46 |
2 | rs1394549346 |
0.8788 | None | 0.954 | N | 0.82 | 0.297 | 0.4318229 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/F | 21758 |
Fn3-46 |
2 | rs1394549346 |
0.8788 | None | 0.954 | N | 0.82 | 0.297 | 0.4318229 | gnomAD-4.0.0 | 1.93389E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.69733E-07 | 2.47488E-05 | 0 |
| P/L | 21957 |
Fn3-47 |
2 | rs879192020 |
0.9924 | -0.534 | 1.0 | D | 0.82 | 0.481 | 0.6779816 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.48E-05 | None | 0 | 0 | 0 |
| P/L | 21957 |
Fn3-47 |
2 | rs879192020 |
0.9924 | -0.534 | 1.0 | D | 0.82 | 0.481 | 0.6779816 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| P/L | 21957 |
Fn3-47 |
2 | rs879192020 |
0.9924 | -0.534 | 1.0 | D | 0.82 | 0.481 | 0.6779816 | gnomAD-4.0.0 | 1.49606E-05 | None | None | None | None | N | None | 5.36049E-05 | 0 | None | 0 | 2.24014E-05 | None | 1.57134E-05 | 0 | 1.44772E-05 | 1.11694E-05 | 0 |
| P/R | 21957 |
Fn3-47 |
2 | None | 0.9985 | None | 1.0 | D | 0.837 | 0.495 | 0.5988224 | gnomAD-4.0.0 | 6.88611E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.03917E-07 | 0 | 0 |
| P/S | 22056 |
Fn3-48 |
2 | rs2047924833 |
0.9789 | None | 1.0 | D | 0.807 | 0.775 | 0.7288316 | gnomAD-4.0.0 | 3.23363E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57289E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 22355 |
Fn3-50 |
2 | rs794729481 |
0.8719 | -1.84 | 0.914 | D | 0.695 | 0.757 | 0.72459865 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/A | 22355 |
Fn3-50 |
2 | rs794729481 |
0.8719 | -1.84 | 0.914 | D | 0.695 | 0.757 | 0.72459865 | gnomAD-4.0.0 | 6.84929E-07 | None | None | None | None | N | None | 0 | 2.24487E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 22355 |
Fn3-50 |
2 | rs794729481 |
0.9835 | -2.415 | 0.987 | D | 0.733 | 0.768 | None | gnomAD-2.1.1 | 2.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 3.99441E-04 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| P/S | 22355 |
Fn3-50 |
2 | rs794729481 |
0.9835 | -2.415 | 0.987 | D | 0.733 | 0.768 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 5.76701E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 22355 |
Fn3-50 |
2 | rs794729481 |
0.9835 | -2.415 | 0.987 | D | 0.733 | 0.768 | None | gnomAD-4.0.0 | 7.44396E-06 | None | None | None | None | N | None | 0 | 0 | None | 2.70599E-04 | 0 | None | 0 | 0 | 8.47971E-07 | 0 | 4.81062E-05 |
| P/A | 22452 |
Fn3-51 |
2 | rs760822987 |
0.786 | -1.051 | 0.999 | N | 0.821 | 0.634 | 0.41758677 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.67766E-04 | None | 0 | None | 0 | 0 | 0 |
| P/A | 22452 |
Fn3-51 |
2 | rs760822987 |
0.786 | -1.051 | 0.999 | N | 0.821 | 0.634 | 0.41758677 | gnomAD-4.0.0 | 2.05388E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.56659E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/H | 22452 |
Fn3-51 |
2 | rs775911087 |
0.9961 | -0.907 | 1.0 | D | 0.783 | 0.69 | 0.5397457 | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79705E-04 | None | 0 | None | 0 | 0 | 0 |
| P/H | 22452 |
Fn3-51 |
2 | rs775911087 |
0.9961 | -0.907 | 1.0 | D | 0.783 | 0.69 | 0.5397457 | gnomAD-4.0.0 | 5.57717E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 9.71736E-04 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 22452 |
Fn3-51 |
2 | rs760822987 |
0.9731 | -1.886 | 1.0 | D | 0.775 | 0.623 | 0.4346062 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.02E-06 | 0 |
| P/S | 22452 |
Fn3-51 |
2 | rs760822987 |
0.9731 | -1.886 | 1.0 | D | 0.775 | 0.623 | 0.4346062 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 22452 |
Fn3-51 |
2 | rs760822987 |
0.9731 | -1.886 | 1.0 | D | 0.775 | 0.623 | 0.4346062 | gnomAD-4.0.0 | 1.4262E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.86537E-05 | 0 | 1.60267E-05 |
| P/T | 22452 |
Fn3-51 |
2 | None | 0.9603 | -1.772 | 1.0 | D | 0.783 | 0.657 | 0.47129235 | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79611E-04 | None | 0 | None | 0 | 0 | 0 |
| P/T | 22452 |
Fn3-51 |
2 | None | 0.9603 | -1.772 | 1.0 | D | 0.783 | 0.657 | 0.47129235 | gnomAD-4.0.0 | 2.39619E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.82768E-04 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 22644 |
Fn3-52 |
2 | rs1366675225 |
0.9953 | None | 1.0 | D | 0.809 | 0.793 | 0.89188546 | gnomAD-4.0.0 | 1.59213E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78087E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 22644 |
Fn3-52 |
2 | None | 0.9941 | None | 1.0 | D | 0.737 | 0.788 | 0.74452573 | gnomAD-4.0.0 | 7.96079E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4299E-05 | 0 | 0 |
| P/R | 22744 |
Fn3-53 |
2 | rs1559481626 |
0.9966 | None | 1.0 | D | 0.836 | 0.599 | 0.5242186 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| P/R | 22744 |
Fn3-53 |
2 | rs1559481626 |
0.9966 | None | 1.0 | D | 0.836 | 0.599 | 0.5242186 | gnomAD-4.0.0 | 1.60031E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86674E-06 | 0 | 0 |
| I/N | 22842 |
Fn3-54 |
2 | None | 0.9525 | None | 0.999 | N | 0.802 | 0.567 | 0.75385493 | gnomAD-4.0.0 | 6.85234E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00075E-07 | 0 | 0 |
| I/T | 22842 |
Fn3-54 |
2 | rs368301580 |
0.5 | -0.726 | 0.999 | N | 0.609 | 0.514 | None | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 2.94E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| I/T | 22842 |
Fn3-54 |
2 | rs368301580 |
0.5 | -0.726 | 0.999 | N | 0.609 | 0.514 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| I/T | 22842 |
Fn3-54 |
2 | rs368301580 |
0.5 | -0.726 | 0.999 | N | 0.609 | 0.514 | None | gnomAD-4.0.0 | 1.79961E-05 | None | None | None | None | N | None | 4.01016E-05 | 1.67802E-05 | None | 0 | 2.23734E-05 | None | 0 | 3.30033E-04 | 1.69635E-05 | 0 | 3.20523E-05 |
| I/V | 22842 |
Fn3-54 |
2 | None | 0.0772 | None | 0.985 | N | 0.277 | 0.206 | 0.52484334 | gnomAD-4.0.0 | 1.37046E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52947E-05 | None | 0 | 0 | 9.00062E-07 | 0 | 0 |
| P/R | 23041 |
Fn3-55 |
2 | rs1174533300 |
0.9975 | None | 1.0 | D | 0.831 | 0.526 | 0.57309973 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 23241 |
Fn3-57 |
2 | None | 0.9628 | None | 1.0 | N | 0.772 | 0.533 | 0.4842566 | gnomAD-4.0.0 | 1.69731E-06 | None | None | None | None | N | None | 6.58155E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 23436 |
Fn3-58 |
2 | None | 0.9875 | None | 1.0 | D | 0.797 | 0.819 | 0.77972215 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/A | 23533 |
Fn3-59 |
2 | rs886055250 |
0.8762 | -1.49 | 0.978 | D | 0.675 | 0.437 | 0.39022037 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| P/A | 23533 |
Fn3-59 |
2 | rs886055250 |
0.8762 | -1.49 | 0.978 | D | 0.675 | 0.437 | 0.39022037 | gnomAD-4.0.0 | 1.59148E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85902E-06 | 0 | 0 |
| P/Q | 23533 |
Fn3-59 |
2 | rs747427532 |
0.9978 | -2.086 | 0.999 | D | 0.877 | 0.518 | 0.49403194 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 1.29232E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/Q | 23533 |
Fn3-59 |
2 | rs747427532 |
0.9978 | -2.086 | 0.999 | D | 0.877 | 0.518 | 0.49403194 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 23533 |
Fn3-59 |
2 | rs747427532 |
0.9978 | -2.086 | 0.999 | D | 0.877 | 0.518 | 0.49403194 | gnomAD-4.0.0 | 3.84413E-06 | None | None | None | None | N | None | 5.07597E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 23533 |
Fn3-59 |
2 | rs886055250 |
0.9889 | None | 0.999 | D | 0.822 | 0.483 | 0.42794093 | gnomAD-4.0.0 | 1.59148E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02425E-05 |
| P/A | 23827 |
Fn3-61 |
2 | None | 0.8162 | None | 0.999 | D | 0.827 | 0.551 | 0.52856195 | gnomAD-4.0.0 | 3.42253E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.4986E-06 | 0 | 0 |
| P/L | 23827 |
Fn3-61 |
2 | None | 0.9621 | None | 1.0 | D | 0.835 | 0.55 | 0.8132307 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| P/S | 23827 |
Fn3-61 |
2 | None | 0.9813 | None | 1.0 | D | 0.788 | 0.56 | 0.52484334 | gnomAD-4.0.0 | 6.84507E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99721E-07 | 0 | 0 |
| P/T | 23827 |
Fn3-61 |
2 | rs756520908 |
0.9759 | -2.062 | 1.0 | D | 0.797 | 0.555 | 0.7011699 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| P/T | 23827 |
Fn3-61 |
2 | rs756520908 |
0.9759 | -2.062 | 1.0 | D | 0.797 | 0.555 | 0.7011699 | gnomAD-4.0.0 | 1.36901E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99721E-07 | 1.16079E-05 | 0 |
| I/M | 23925 |
Fn3-62 |
2 | rs1401717606 |
0.1838 | -0.74 | 0.93 | N | 0.545 | 0.146 | 0.07629995 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| I/M | 23925 |
Fn3-62 |
2 | rs1401717606 |
0.1838 | -0.74 | 0.93 | N | 0.545 | 0.146 | 0.07629995 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/M | 23925 |
Fn3-62 |
2 | rs1401717606 |
0.1838 | -0.74 | 0.93 | N | 0.545 | 0.146 | 0.07629995 | gnomAD-4.0.0 | 2.10725E-05 | None | None | None | None | N | None | 2.67023E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.71264E-05 | 0 | 0 |
| I/N | 23925 |
Fn3-62 |
2 | rs374887185 |
0.8307 | -1.259 | 0.976 | N | 0.671 | 0.382 | None | gnomAD-2.1.1 | 7.14E-06 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/N | 23925 |
Fn3-62 |
2 | rs374887185 |
0.8307 | -1.259 | 0.976 | N | 0.671 | 0.382 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20697E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/N | 23925 |
Fn3-62 |
2 | rs374887185 |
0.8307 | -1.259 | 0.976 | N | 0.671 | 0.382 | None | gnomAD-4.0.0 | 3.71871E-06 | None | None | None | None | N | None | 8.01239E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 23925 |
Fn3-62 |
2 | rs374887185 |
0.19 | -1.797 | 0.651 | N | 0.579 | 0.293 | 0.3173784 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 8.88E-06 | 0 |
| I/T | 23925 |
Fn3-62 |
2 | rs374887185 |
0.19 | -1.797 | 0.651 | N | 0.579 | 0.293 | 0.3173784 | gnomAD-4.0.0 | 6.84282E-06 | None | None | None | None | N | None | 0 | 2.23624E-05 | None | 0 | 0 | None | 0 | 0 | 8.0959E-06 | 0 | 0 |
| P/A | 24123 |
Fn3-63 |
2 | rs1709083806 |
0.918 | None | 0.999 | D | 0.795 | 0.655 | 0.79035413 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 24123 |
Fn3-63 |
2 | rs1709083806 |
0.918 | None | 0.999 | D | 0.795 | 0.655 | 0.79035413 | gnomAD-4.0.0 | 6.57644E-06 | None | None | None | None | N | None | 2.41488E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 24123 |
Fn3-63 |
2 | None | 0.9878 | None | 1.0 | D | 0.773 | 0.655 | 0.8386431 | gnomAD-4.0.0 | 1.62491E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.91418E-06 | 0 | 0 |
| P/S | 24223 |
Fn3-64 |
2 | rs760890661 |
0.7593 | -2.45 | 0.249 | N | 0.494 | 0.403 | 0.32306182 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| P/S | 24223 |
Fn3-64 |
2 | rs760890661 |
0.7593 | -2.45 | 0.249 | N | 0.494 | 0.403 | 0.32306182 | gnomAD-4.0.0 | 2.6417E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.52353E-06 | 0 | 0 |
| P/A | 24520 |
Fn3-66 |
2 | rs780474186 |
0.9369 | -1.585 | 1.0 | D | 0.826 | 0.596 | 0.7581696 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| P/A | 24520 |
Fn3-66 |
2 | rs780474186 |
0.9369 | -1.585 | 1.0 | D | 0.826 | 0.596 | 0.7581696 | gnomAD-4.0.0 | 6.84346E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52449E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 24520 |
Fn3-66 |
2 | None | 0.9924 | None | 1.0 | D | 0.821 | 0.608 | 0.90506893 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/T | 24520 |
Fn3-66 |
2 | None | 0.9934 | None | 1.0 | D | 0.774 | 0.588 | 0.793965 | gnomAD-4.0.0 | 6.84346E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99586E-07 | 0 | 0 |
| P/R | 24617 |
Fn3-67 |
2 | rs1423389429 |
0.9983 | -1.639 | 1.0 | D | 0.785 | 0.592 | 0.6190935 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/R | 24617 |
Fn3-67 |
2 | rs1423389429 |
0.9983 | -1.639 | 1.0 | D | 0.785 | 0.592 | 0.6190935 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 24617 |
Fn3-67 |
2 | rs1423389429 |
0.9983 | -1.639 | 1.0 | D | 0.785 | 0.592 | 0.6190935 | gnomAD-4.0.0 | 2.56495E-06 | None | None | None | None | N | None | 3.38409E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/H | 24909 |
Fn3-69 |
2 | None | 0.9967 | None | 1.0 | D | 0.802 | 0.575 | 0.74572647 | gnomAD-4.0.0 | 1.59197E-06 | None | None | None | None | N | None | 5.66123E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 24909 |
Fn3-69 |
2 | None | 0.9614 | None | 1.0 | D | 0.884 | 0.562 | 0.82707006 | gnomAD-4.0.0 | 1.59197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| C/S | 25007 |
Fn3-70 |
2 | None | 0.7358 | None | 0.999 | N | 0.768 | 0.54 | 0.35996303 | gnomAD-4.0.0 | 6.84347E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99593E-07 | 0 | 0 |
| C/Y | 25007 |
Fn3-70 |
2 | rs1419626284 |
0.9478 | -1.482 | 0.999 | N | 0.819 | 0.438 | 0.3817464 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| C/Y | 25007 |
Fn3-70 |
2 | rs1419626284 |
0.9478 | -1.482 | 0.999 | N | 0.819 | 0.438 | 0.3817464 | gnomAD-4.0.0 | 2.05304E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69878E-06 | 0 | 0 |
| P/L | 25205 |
Fn3-71 |
2 | rs1324051113 |
0.9747 | -0.825 | 1.0 | D | 0.814 | 0.786 | 0.9168837 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| P/L | 25205 |
Fn3-71 |
2 | rs1324051113 |
0.9747 | -0.825 | 1.0 | D | 0.814 | 0.786 | 0.9168837 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/L | 25205 |
Fn3-71 |
2 | rs1324051113 |
0.9747 | -0.825 | 1.0 | D | 0.814 | 0.786 | 0.9168837 | gnomAD-4.0.0 | 6.81925E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47781E-06 | 0 | 1.6019E-05 |
| P/L | 25305 |
Fn3-72 |
2 | rs142453163 |
0.9443 | -0.257 | 0.027 | D | 0.622 | 0.475 | None | gnomAD-2.1.1 | 9.66E-05 | None | None | None | None | N | None | 0 | 8.5E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.88156E-04 | 0 |
| P/L | 25305 |
Fn3-72 |
2 | rs142453163 |
0.9443 | -0.257 | 0.027 | D | 0.622 | 0.475 | None | gnomAD-3.1.2 | 1.11857E-04 | None | None | None | None | N | None | 2.42E-05 | 2.62467E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.76507E-04 | 0 | 0 |
| P/L | 25305 |
Fn3-72 |
2 | rs142453163 |
0.9443 | -0.257 | 0.027 | D | 0.622 | 0.475 | None | gnomAD-4.0.0 | 1.20247E-04 | None | None | None | None | N | None | 1.33422E-05 | 1.50115E-04 | None | 0 | 0 | None | 0 | 0 | 1.54288E-04 | 0 | 3.20195E-05 |
| P/S | 25305 |
Fn3-72 |
2 | rs1005621705 |
0.8783 | -2.146 | 0.256 | D | 0.458 | 0.531 | 0.3803943 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| P/S | 25305 |
Fn3-72 |
2 | rs1005621705 |
0.8783 | -2.146 | 0.256 | D | 0.458 | 0.531 | 0.3803943 | gnomAD-4.0.0 | 1.16339E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52929E-05 | 0 | 0 |
| P/Q | 25406 |
Fn3-73 |
2 | None | 0.9962 | None | 1.0 | D | 0.769 | 0.613 | 0.71665823 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| P/R | 25406 |
Fn3-73 |
2 | rs771016168 |
0.9955 | -1.219 | 0.999 | D | 0.76 | 0.609 | 0.75504035 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| P/S | 25602 |
Fn3-74 |
2 | rs1707254187 |
0.9866 | None | 0.997 | D | 0.717 | 0.704 | 0.7358422 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 25602 |
Fn3-74 |
2 | rs1707254187 |
0.9866 | None | 0.997 | D | 0.717 | 0.704 | 0.7358422 | gnomAD-4.0.0 | 2.03009E-06 | None | None | None | None | N | None | 1.7477E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20498E-06 | 0 | 0 |
| P/S | 25699 |
Fn3-75 |
2 | rs1435124022 |
0.9931 | None | 1.0 | D | 0.752 | 0.609 | 0.49124897 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 25699 |
Fn3-75 |
2 | rs1435124022 |
0.9931 | None | 1.0 | D | 0.752 | 0.609 | 0.49124897 | gnomAD-4.0.0 | 6.57756E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47093E-05 | 0 | 0 |
| P/H | 25891 |
Fn3-76 |
2 | rs766099071 |
0.9989 | None | 1.0 | D | 0.75 | 0.634 | 0.8609167 | gnomAD-4.0.0 | 2.73758E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59843E-06 | 0 | 0 |
| P/L | 25891 |
Fn3-76 |
2 | rs766099071 |
0.9807 | None | 1.0 | D | 0.806 | 0.618 | None | gnomAD-4.0.0 | 1.43723E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.88918E-05 | 0 | 0 |
| P/R | 25891 |
Fn3-76 |
2 | None | 0.9971 | None | 1.0 | D | 0.809 | 0.634 | 0.8423708 | gnomAD-4.0.0 | 6.84396E-07 | None | None | None | None | N | None | 0 | 2.23784E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 25891 |
Fn3-76 |
2 | None | 0.9957 | None | 1.0 | D | 0.765 | 0.651 | 0.7971233 | gnomAD-4.0.0 | 6.84387E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99604E-07 | 0 | 0 |
| P/T | 25891 |
Fn3-76 |
2 | rs1214607347 |
0.9898 | -2.316 | 1.0 | D | 0.774 | 0.654 | 0.81415886 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/T | 25891 |
Fn3-76 |
2 | rs1214607347 |
0.9898 | -2.316 | 1.0 | D | 0.774 | 0.654 | 0.81415886 | gnomAD-4.0.0 | 2.73755E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52512E-05 | None | 0 | 0 | 1.79921E-06 | 1.15947E-05 | 0 |
| P/S | 26287 |
Fn3-79 |
2 | rs1451385344 |
0.9968 | None | 1.0 | D | 0.767 | 0.791 | 0.8114232 | gnomAD-4.0.0 | 1.3744E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01585E-07 | 1.1773E-05 | 0 |
| P/L | 26488 |
Fn3-81 |
2 | None | 0.9719 | None | 1.0 | D | 0.837 | 0.706 | 0.9086447 | gnomAD-4.0.0 | 1.36894E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79906E-06 | 0 | 0 |
| P/S | 26488 |
Fn3-81 |
2 | None | 0.9852 | None | 1.0 | D | 0.776 | 0.737 | 0.6779273 | gnomAD-4.0.0 | 1.59263E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85886E-06 | 0 | 0 |
| P/A | 26684 |
Fn3-82 |
2 | rs1705731534 |
0.8801 | None | 1.0 | D | 0.82 | 0.717 | 0.7168393 | gnomAD-4.0.0 | 2.05278E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69861E-06 | 0 | 0 |
| P/A | 26973 |
Fn3-84 |
2 | rs148598047 |
0.8904 | -2.098 | 0.999 | D | 0.841 | 0.703 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| P/A | 26973 |
Fn3-84 |
2 | rs148598047 |
0.8904 | -2.098 | 0.999 | D | 0.841 | 0.703 | None | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 1.24131E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/A | 26973 |
Fn3-84 |
2 | rs148598047 |
0.8904 | -2.098 | 0.999 | D | 0.841 | 0.703 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 1.93125E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 26973 |
Fn3-84 |
2 | rs148598047 |
0.8904 | -2.098 | 0.999 | D | 0.841 | 0.703 | None | gnomAD-4.0.0 | 6.81734E-06 | None | None | None | None | N | None | 1.46667E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 27073 |
Fn3-85 |
2 | None | 0.9878 | None | 1.0 | D | 0.82 | 0.527 | 0.67170393 | gnomAD-4.0.0 | 6.84848E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99841E-07 | 0 | 0 |
| P/S | 27073 |
Fn3-85 |
2 | rs542799302 |
0.9829 | -2.207 | 1.0 | D | 0.789 | 0.516 | 0.5658299 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 2E-03 | None |
| P/S | 27073 |
Fn3-85 |
2 | rs542799302 |
0.9829 | -2.207 | 1.0 | D | 0.789 | 0.516 | 0.5658299 | gnomAD-2.1.1 | 4.86E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.97825E-04 | None | 0 | 0 | 0 |
| P/S | 27073 |
Fn3-85 |
2 | rs542799302 |
0.9829 | -2.207 | 1.0 | D | 0.789 | 0.516 | 0.5658299 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.13907E-04 | 0 |
| P/S | 27073 |
Fn3-85 |
2 | rs542799302 |
0.9829 | -2.207 | 1.0 | D | 0.789 | 0.516 | 0.5658299 | gnomAD-4.0.0 | 2.1707E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54384E-06 | 3.30644E-04 | 3.20564E-05 |
| C/R | 27171 |
Fn3-86 |
2 | rs727504678 |
0.9796 | -0.116 | 0.015 | N | 0.651 | 0.405 | 0.516884 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.9E-06 | 0 |
| C/R | 27171 |
Fn3-86 |
2 | rs727504678 |
0.9796 | -0.116 | 0.015 | N | 0.651 | 0.405 | 0.516884 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/R | 27171 |
Fn3-86 |
2 | rs727504678 |
0.9796 | -0.116 | 0.015 | N | 0.651 | 0.405 | 0.516884 | gnomAD-4.0.0 | 7.43746E-06 | None | None | None | None | N | None | 0 | 6.67045E-05 | None | 0 | 0 | None | 0 | 0 | 5.08603E-06 | 2.19597E-05 | 0 |
| C/Y | 27171 |
Fn3-86 |
2 | None | 0.9509 | None | 0.979 | N | 0.658 | 0.411 | 0.48034996 | gnomAD-4.0.0 | 1.59192E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85904E-06 | 0 | 0 |
| P/L | 27370 |
Fn3-87 |
2 | rs1396821599 |
0.9631 | -0.524 | 1.0 | D | 0.785 | 0.507 | 0.8205535 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 27370 |
Fn3-87 |
2 | rs1396821599 |
0.9631 | -0.524 | 1.0 | D | 0.785 | 0.507 | 0.8205535 | gnomAD-4.0.0 | 1.59134E-06 | None | None | None | None | N | None | 5.65611E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 27370 |
Fn3-87 |
2 | None | 0.9832 | None | 1.0 | D | 0.744 | 0.517 | 0.6083708 | gnomAD-4.0.0 | 4.10533E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39696E-06 | 0 | 0 |
| P/T | 27470 |
Fn3-88 |
2 | rs886055239 |
0.8401 | -2.052 | 1.0 | D | 0.793 | 0.64 | 0.825529 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| P/T | 27470 |
Fn3-88 |
2 | rs886055239 |
0.8401 | -2.052 | 1.0 | D | 0.793 | 0.64 | 0.825529 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/T | 27470 |
Fn3-88 |
2 | rs886055239 |
0.8401 | -2.052 | 1.0 | D | 0.793 | 0.64 | 0.825529 | gnomAD-4.0.0 | 4.33812E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08579E-06 | 0 | 1.60108E-05 |
| P/L | 27571 |
Fn3-89 |
2 | None | 0.9502 | None | 1.0 | D | 0.843 | 0.575 | 0.74122936 | gnomAD-4.0.0 | 1.36851E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.82731E-05 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| P/S | 27571 |
Fn3-89 |
2 | None | 0.9549 | None | 1.0 | D | 0.795 | 0.531 | None | gnomAD-4.0.0 | 2.05277E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69845E-06 | 0 | 0 |
| P/L | 27767 |
Fn3-90 |
2 | rs753567973 |
0.9877 | -0.489 | 1.0 | D | 0.827 | 0.618 | 0.9031091 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| P/L | 27767 |
Fn3-90 |
2 | rs753567973 |
0.9877 | -0.489 | 1.0 | D | 0.827 | 0.618 | 0.9031091 | gnomAD-4.0.0 | 1.59317E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43357E-05 | 0 |
| P/Q | 27767 |
Fn3-90 |
2 | rs753567973 |
0.9987 | -1.89 | 1.0 | D | 0.799 | 0.621 | 0.78405184 | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.49E-05 | 0 |
| P/Q | 27767 |
Fn3-90 |
2 | rs753567973 |
0.9987 | -1.89 | 1.0 | D | 0.799 | 0.621 | 0.78405184 | gnomAD-4.0.0 | 1.59317E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86056E-05 | 0 | 0 |
| P/T | 27767 |
Fn3-90 |
2 | rs184643087 |
0.9905 | -1.919 | 1.0 | D | 0.746 | 0.639 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| P/T | 27767 |
Fn3-90 |
2 | rs184643087 |
0.9905 | -1.919 | 1.0 | D | 0.746 | 0.639 | None | gnomAD-2.1.1 | 2.37398E-04 | None | None | None | None | N | None | 2.50188E-03 | 1.13792E-04 | None | 0 | 0 | None | 0 | None | 0 | 7.88E-06 | 1.41323E-04 |
| P/T | 27767 |
Fn3-90 |
2 | rs184643087 |
0.9905 | -1.919 | 1.0 | D | 0.746 | 0.639 | None | gnomAD-3.1.2 | 7.56191E-04 | None | None | None | None | N | None | 2.72881E-03 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| P/T | 27767 |
Fn3-90 |
2 | rs184643087 |
0.9905 | -1.919 | 1.0 | D | 0.746 | 0.639 | None | gnomAD-4.0.0 | 1.31432E-04 | None | None | None | None | N | None | 2.53367E-03 | 1.5025E-04 | None | 0 | 0 | None | 0 | 0 | 5.0869E-06 | 0 | 1.12144E-04 |
| P/L | 27864 |
Fn3-91 |
2 | rs1205644458 |
0.8366 | None | 1.0 | D | 0.847 | 0.678 | 0.74506086 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/L | 27864 |
Fn3-91 |
2 | rs1205644458 |
0.8366 | None | 1.0 | D | 0.847 | 0.678 | 0.74506086 | gnomAD-4.0.0 | 1.24207E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69691E-06 | 0 | 0 |
| P/S | 27864 |
Fn3-91 |
2 | rs1553568366 |
0.9643 | None | 1.0 | D | 0.797 | 0.612 | 0.53698826 | gnomAD-4.0.0 | 1.37161E-06 | None | None | None | None | N | None | 3.00625E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0039E-07 | 0 | 0 |
| P/T | 27864 |
Fn3-91 |
2 | None | 0.9392 | None | 1.0 | N | 0.805 | 0.614 | 0.5538333 | gnomAD-4.0.0 | 6.85804E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0039E-07 | 0 | 0 |
| P/A | 28056 |
Fn3-92 |
2 | None | 0.9243 | None | 0.999 | D | 0.843 | 0.593 | 0.7820292 | gnomAD-4.0.0 | 1.59315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78272E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 28056 |
Fn3-92 |
2 | None | 0.9955 | None | 1.0 | D | 0.859 | 0.581 | 0.83584374 | gnomAD-4.0.0 | 1.59324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86236E-06 | 0 | 0 |
| P/S | 28155 |
Fn3-93 |
2 | None | 0.9717 | None | 1.0 | D | 0.772 | 0.517 | 0.57942986 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| C/R | 28253 |
Fn3-94 |
2 | None | 0.972 | None | 0.999 | N | 0.848 | 0.563 | 0.709402 | gnomAD-4.0.0 | 1.36841E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51915E-05 | None | 0 | 0 | 8.99467E-07 | 0 | 0 |
| C/Y | 28253 |
Fn3-94 |
2 | rs754491290 |
0.9468 | -0.996 | 0.999 | N | 0.852 | 0.449 | 0.5345724 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| C/Y | 28253 |
Fn3-94 |
2 | rs754491290 |
0.9468 | -0.996 | 0.999 | N | 0.852 | 0.449 | 0.5345724 | gnomAD-4.0.0 | 2.0526E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.47794E-05 | 0 |
| P/S | 28451 |
Fn3-95 |
2 | rs727503554 |
0.9653 | -2.495 | 1.0 | D | 0.799 | 0.512 | 0.57033706 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/S | 28451 |
Fn3-95 |
2 | rs727503554 |
0.9653 | -2.495 | 1.0 | D | 0.799 | 0.512 | 0.57033706 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 28451 |
Fn3-95 |
2 | rs727503554 |
0.9653 | -2.495 | 1.0 | D | 0.799 | 0.512 | 0.57033706 | gnomAD-4.0.0 | 3.09865E-06 | None | None | None | None | N | None | 6.67414E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 28551 |
Fn3-96 |
2 | None | 0.9771 | None | 1.0 | D | 0.816 | 0.785 | 0.81426257 | gnomAD-4.0.0 | 1.59255E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85958E-06 | 0 | 0 |
| P/T | 28551 |
Fn3-96 |
2 | rs142478636 |
0.8714 | -2.064 | 1.0 | D | 0.821 | 0.669 | None | 1000 genomes | 7.98722E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 4E-03 | 0 | None | None | None | 0 | None |
| P/T | 28551 |
Fn3-96 |
2 | rs142478636 |
0.8714 | -2.064 | 1.0 | D | 0.821 | 0.669 | None | gnomAD-2.1.1 | 1.97059E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.37407E-03 | None | 6.55E-05 | None | 0 | 4.7E-05 | 1.41323E-04 |
| P/T | 28551 |
Fn3-96 |
2 | rs142478636 |
0.8714 | -2.064 | 1.0 | D | 0.821 | 0.669 | None | gnomAD-3.1.2 | 1.51298E-04 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.28566E-03 | None | 0 | 0 | 4.41E-05 | 2.07814E-04 | 9.56023E-04 |
| P/T | 28551 |
Fn3-96 |
2 | rs142478636 |
0.8714 | -2.064 | 1.0 | D | 0.821 | 0.669 | None | gnomAD-4.0.0 | 1.8163E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.25093E-03 | None | 0 | 0 | 3.13665E-05 | 1.42823E-04 | 1.2809E-04 |
| P/L | 28652 |
Fn3-97 |
2 | None | 0.9687 | None | 1.0 | D | 0.816 | 0.455 | 0.8145665 | gnomAD-4.0.0 | 1.36844E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79896E-06 | 0 | 0 |
| P/L | 28943 |
Fn3-99 |
2 | rs917359469 |
0.9441 | -0.387 | 1.0 | D | 0.89 | 0.568 | 0.71726036 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 28943 |
Fn3-99 |
2 | rs917359469 |
0.9441 | -0.387 | 1.0 | D | 0.89 | 0.568 | 0.71726036 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 28943 |
Fn3-99 |
2 | rs917359469 |
0.9441 | -0.387 | 1.0 | D | 0.89 | 0.568 | 0.71726036 | gnomAD-4.0.0 | 3.8641E-06 | None | None | None | None | N | None | 5.09182E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 28943 |
Fn3-99 |
2 | rs917359469 |
0.9964 | -2.083 | 1.0 | D | 0.886 | 0.613 | 0.5880822 | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.1E-06 | 0 |
| P/Q | 28943 |
Fn3-99 |
2 | rs917359469 |
0.9964 | -2.083 | 1.0 | D | 0.886 | 0.613 | 0.5880822 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/Q | 28943 |
Fn3-99 |
2 | rs917359469 |
0.9964 | -2.083 | 1.0 | D | 0.886 | 0.613 | 0.5880822 | gnomAD-4.0.0 | 2.57606E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.59129E-05 | 0 | 2.39707E-06 | 0 | 0 |
| P/T | 29138 |
Fn3-100 |
2 | rs72648227 |
0.9863 | -2.667 | 1.0 | D | 0.834 | 0.724 | None | 1000 genomes | 2.19649E-03 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 4E-03 | None | None | None | 6.1E-03 | None |
| P/T | 29138 |
Fn3-100 |
2 | rs72648227 |
0.9863 | -2.667 | 1.0 | D | 0.834 | 0.724 | None | gnomAD-2.1.1 | 1.18768E-03 | None | None | None | None | N | None | 4.13E-05 | 5.3727E-04 | None | 7.15667E-03 | 0 | None | 3.69257E-03 | None | 1.10493E-03 | 6.4862E-04 | 2.10852E-03 |
| P/T | 29138 |
Fn3-100 |
2 | rs72648227 |
0.9863 | -2.667 | 1.0 | D | 0.834 | 0.724 | None | gnomAD-3.1.2 | 8.80559E-04 | None | None | None | None | N | None | 1.20656E-04 | 1.76748E-03 | 0 | 7.7765E-03 | 0 | None | 1.31827E-03 | 0 | 5.43878E-04 | 4.76585E-03 | 4.77555E-04 |
| P/T | 29138 |
Fn3-100 |
2 | rs72648227 |
0.9863 | -2.667 | 1.0 | D | 0.834 | 0.724 | None | gnomAD-4.0.0 | 8.70411E-04 | None | None | None | None | N | None | 1.19933E-04 | 9.16361E-04 | None | 7.05938E-03 | 2.22846E-05 | None | 1.61597E-03 | 2.31023E-03 | 4.73791E-04 | 4.22705E-03 | 1.1205E-03 |
| P/S | 29238 |
Fn3-101 |
2 | rs1701983890 |
0.9832 | None | 1.0 | D | 0.801 | 0.495 | 0.5242186 | gnomAD-4.0.0 | 1.20035E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
| C/G | 29336 |
Fn3-102 |
2 | rs1701872687 |
0.7737 | None | 0.999 | N | 0.827 | 0.591 | 0.6379611 | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8578E-06 | 0 | 0 |
| C/S | 29336 |
Fn3-102 |
2 | rs1328042296 |
0.8146 | None | 0.999 | N | 0.77 | 0.523 | 0.43795878 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/S | 29336 |
Fn3-102 |
2 | rs1328042296 |
0.8146 | None | 0.999 | N | 0.77 | 0.523 | 0.43795878 | gnomAD-4.0.0 | 6.56625E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47016E-05 | 0 | 0 |
| C/Y | 29336 |
Fn3-102 |
2 | rs1328042296 |
0.9736 | -0.707 | 0.999 | N | 0.847 | 0.416 | 0.51299894 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| C/Y | 29336 |
Fn3-102 |
2 | rs1328042296 |
0.9736 | -0.707 | 0.999 | N | 0.847 | 0.416 | 0.51299894 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 29336 |
Fn3-102 |
2 | rs1328042296 |
0.9736 | -0.707 | 0.999 | N | 0.847 | 0.416 | 0.51299894 | gnomAD-4.0.0 | 3.84326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78538E-06 | 0 | 2.84463E-05 |
| P/L | 29534 |
Fn3-103 |
2 | rs760009798 |
0.9413 | 0.053 | 1.0 | D | 0.859 | 0.711 | 0.9383417 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| P/L | 29534 |
Fn3-103 |
2 | rs760009798 |
0.9413 | 0.053 | 1.0 | D | 0.859 | 0.711 | 0.9383417 | gnomAD-4.0.0 | 1.36875E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79901E-06 | 0 | 0 |
| P/S | 29534 |
Fn3-103 |
2 | None | 0.9796 | None | 1.0 | D | 0.834 | 0.735 | 0.8033726 | gnomAD-4.0.0 | 4.10614E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.397E-06 | 0 | 0 |
| P/A | 29634 |
Fn3-104 |
2 | rs1559226382 |
0.5692 | None | 0.999 | N | 0.841 | 0.487 | 0.49838725 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 29634 |
Fn3-104 |
2 | rs1559226382 |
0.5692 | None | 0.999 | N | 0.841 | 0.487 | 0.49838725 | gnomAD-4.0.0 | 1.31456E-05 | None | None | None | None | N | None | 4.82532E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 29634 |
Fn3-104 |
2 | None | 0.9597 | None | 1.0 | D | 0.863 | 0.541 | 0.7952593 | gnomAD-4.0.0 | 2.40079E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62514E-06 | 0 | 0 |
| P/S | 29634 |
Fn3-104 |
2 | None | 0.9244 | None | 1.0 | D | 0.807 | 0.516 | 0.5576749 | gnomAD-4.0.0 | 1.6715E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.5649E-05 | 0 |
| P/L | 29934 |
Fn3-106 |
2 | None | 0.983 | None | 1.0 | D | 0.85 | 0.578 | 0.75932986 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 30031 |
Fn3-107 |
2 | rs538582097 |
0.9901 | -2.555 | 1.0 | D | 0.786 | 0.705 | 0.7646961 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| P/S | 30031 |
Fn3-107 |
2 | rs538582097 |
0.9901 | -2.555 | 1.0 | D | 0.786 | 0.705 | 0.7646961 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 30031 |
Fn3-107 |
2 | rs538582097 |
0.9901 | -2.555 | 1.0 | D | 0.786 | 0.705 | 0.7646961 | gnomAD-4.0.0 | 2.02964E-06 | None | None | None | None | N | None | 0 | 6.14477E-05 | None | 0 | 0 | None | 0 | 0 | 1.20493E-06 | 0 | 0 |
| P/T | 30031 |
Fn3-107 |
2 | rs538582097 |
0.9843 | -2.363 | 1.0 | D | 0.806 | 0.696 | 0.78446233 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| P/S | 30225 |
Fn3-108 |
2 | None | 0.9873 | None | 1.0 | D | 0.8 | 0.527 | 0.516884 | gnomAD-4.0.0 | 1.59227E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85964E-06 | 0 | 0 |
| P/A | 30325 |
Fn3-109 |
2 | None | 0.7541 | None | 0.999 | D | 0.801 | 0.717 | 0.7365176 | gnomAD-4.0.0 | 3.42126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.5582E-05 | None | 0 | 0 | 0 | 0 | 3.31312E-05 |
| P/S | 30325 |
Fn3-109 |
2 | None | 0.9674 | None | 1.0 | D | 0.739 | 0.736 | 0.7461159 | gnomAD-4.0.0 | 6.84252E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15953E-05 | 0 |
| V/I | 30423 |
Fn3-110 |
2 | rs1699485019 |
0.1118 | None | 0.994 | N | 0.587 | 0.245 | 0.28684884 | gnomAD-4.0.0 | 1.05561E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.83024E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 30423 |
Fn3-110 |
2 | None | 0.7139 | None | 0.994 | N | 0.617 | 0.255 | 0.24677357 | gnomAD-4.0.0 | 7.03737E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.15498E-07 | 0 | 0 |
| P/A | 30620 |
Fn3-111 |
2 | None | 0.8015 | None | 0.999 | D | 0.837 | 0.835 | 0.7646204 | gnomAD-4.0.0 | 1.74574E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.07649E-06 | 0 | 0 |
| P/S | 30620 |
Fn3-111 |
2 | None | 0.9787 | None | 1.0 | D | 0.813 | 0.827 | 0.7783478 | gnomAD-4.0.0 | 1.74574E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.07649E-06 | 0 | 0 |
| P/L | 30822 |
Fn3-113 |
2 | None | 0.9264 | None | 1.0 | D | 0.831 | 0.685 | 0.8504108 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| P/R | 30822 |
Fn3-113 |
2 | None | 0.9807 | None | 1.0 | D | 0.808 | 0.711 | 0.76609457 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/L | 31114 |
Fn3-115 |
2 | rs1698006505 |
0.9581 | None | 1.0 | D | 0.846 | 0.601 | 0.8518933 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| P/L | 31309 |
Fn3-116 |
2 | rs1697796089 |
0.9711 | None | 1.0 | D | 0.847 | 0.675 | 0.8718784 | gnomAD-4.0.0 | 1.59106E-06 | None | None | None | None | N | None | 0 | 2.28655E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 31409 |
Fn3-117 |
2 | None | 0.9982 | None | 1.0 | D | 0.829 | 0.514 | 0.70180297 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62502E-06 | 0 | 0 |
| P/S | 31409 |
Fn3-117 |
2 | rs1464695009 |
0.9881 | -2.196 | 1.0 | D | 0.759 | 0.496 | 0.4953044 | gnomAD-2.1.1 | 1.24E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.03505E-04 | None | 0 | 0 | 0 |
| P/S | 31409 |
Fn3-117 |
2 | rs1464695009 |
0.9881 | -2.196 | 1.0 | D | 0.759 | 0.496 | 0.4953044 | gnomAD-4.0.0 | 8.07935E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 7.29778E-05 | 0 |
| V/A | 31507 |
Fn3-118 |
2 | rs371097838 |
0.7119 | -1.415 | 0.997 | N | 0.456 | 0.357 | None | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/A | 31507 |
Fn3-118 |
2 | rs371097838 |
0.7119 | -1.415 | 0.997 | N | 0.456 | 0.357 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 31507 |
Fn3-118 |
2 | rs371097838 |
0.7119 | -1.415 | 0.997 | N | 0.456 | 0.357 | None | gnomAD-4.0.0 | 4.35404E-06 | None | None | None | None | N | None | 6.69649E-05 | 0 | None | 0 | 0 | None | 1.56853E-05 | 0 | 8.50608E-07 | 0 | 0 |
| P/H | 31709 |
Fn3-119 |
2 | rs869320739 |
0.9968 | None | 0.999 | D | 0.744 | 0.603 | 0.53060657 |
Palmio (2019)
| None |
HMERF
|
het | None | None | N | Genetic analysis of genes in 12 HMERF families; co-segregates with condition (n = 1, 1 affected (total 2)) | None | None | None | None | None | None | None | None | None | None | None |
| P/R | 31709 |
Fn3-119 |
2 | rs869320739 |
0.9921 | -0.93 | 0.235 | D | 0.464 | 0.811 | 0.36256343 |
Palmio (2013)
Hedberg (2014)
| None |
HMERF
|
het | None | None | N | WES/WGS prioritisation in 12 HMERF families; dominant effect, full penetrance (n = 3, 3 affected (total 6)) | None | None | None | None | None | None | None | None | None | None | None |
| P/Q | 31808 |
Fn3-120 |
2 | None | 0.9946 | None | 1.0 | D | 0.753 | 0.726 | 0.763426 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| P/A | 31910 |
Fn3-121 |
2 | None | 0.6622 | None | 0.999 | D | 0.805 | 0.45 | 0.5290608 | gnomAD-4.0.0 | 1.65955E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.14446E-05 |
| P/L | 31910 |
Fn3-121 |
2 | None | 0.928 | None | 1.0 | D | 0.854 | 0.437 | 0.7290335 | gnomAD-4.0.0 | 6.94496E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.12129E-07 | 0 | 0 |
| P/S | 31910 |
Fn3-121 |
2 | rs199618831 |
0.9577 | -2.555 | 1.0 | D | 0.759 | 0.464 | 0.5244809 | gnomAD-2.1.1 | 8.39E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.84E-05 | 0 |
| P/S | 31910 |
Fn3-121 |
2 | rs199618831 |
0.9577 | -2.555 | 1.0 | D | 0.759 | 0.464 | 0.5244809 | gnomAD-4.0.0 | 4.97866E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.98008E-04 | 3.00582E-06 | 0 | 0 |
| P/A | 32400 |
Fn3-124 |
2 | rs373876117 |
0.9158 | -2.028 | 0.999 | D | 0.851 | 0.667 | 0.7048481 | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.1E-06 | 0 |
| P/A | 32400 |
Fn3-124 |
2 | rs373876117 |
0.9158 | -2.028 | 0.999 | D | 0.851 | 0.667 | 0.7048481 | gnomAD-4.0.0 | 4.83393E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.34932E-06 | 0 | 0 |
| P/T | 32400 |
Fn3-124 |
2 | rs373876117 |
0.987 | -2.384 | 1.0 | D | 0.885 | 0.679 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| P/T | 32400 |
Fn3-124 |
2 | rs373876117 |
0.987 | -2.384 | 1.0 | D | 0.885 | 0.679 | None | gnomAD-2.1.1 | 1.16761E-04 | None | None | None | None | N | None | 0 | 1.7188E-04 | None | 0 | 0 | None | 0 | None | 0 | 1.75531E-04 | 5.74218E-04 |
| P/T | 32400 |
Fn3-124 |
2 | rs373876117 |
0.987 | -2.384 | 1.0 | D | 0.885 | 0.679 | None | gnomAD-3.1.2 | 1.18343E-04 | None | None | None | None | N | None | 0 | 3.2774E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.32337E-04 | 0 | 1.91022E-03 |
| P/T | 32400 |
Fn3-124 |
2 | rs373876117 |
0.987 | -2.384 | 1.0 | D | 0.885 | 0.679 | None | gnomAD-4.0.0 | 1.28725E-04 | None | None | None | None | N | None | 2.67931E-05 | 2.35603E-04 | None | 0 | 0 | None | 0 | 0 | 1.52074E-04 | 0 | 1.94143E-04 |
| P/L | 32500 |
Fn3-125 |
2 | None | 0.9168 | None | 1.0 | D | 0.84 | 0.763 | 0.8751501 | gnomAD-4.0.0 | 6.88078E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.03524E-07 | 0 | 0 |
| P/L | 32601 |
Fn3-126 |
2 | rs745324961 |
0.9253 | -0.109 | 1.0 | D | 0.856 | 0.485 | 0.81547034 | gnomAD-2.1.1 | 8.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| P/L | 32601 |
Fn3-126 |
2 | rs745324961 |
0.9253 | -0.109 | 1.0 | D | 0.856 | 0.485 | 0.81547034 | gnomAD-4.0.0 | 3.19649E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.74257E-06 | 0 | 0 |
| P/A | 32796 |
Fn3-127 |
2 | rs1693423139 |
0.9094 | None | 0.999 | D | 0.876 | 0.644 | 0.64223254 | gnomAD-4.0.0 | 1.59158E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02352E-05 |
| P/L | 32796 |
Fn3-127 |
2 | None | 0.9799 | None | 1.0 | D | 0.922 | 0.717 | 0.81531084 | gnomAD-4.0.0 | 8.89541E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.16929E-05 | 0 | 0 |
| P/S | 32796 |
Fn3-127 |
2 | None | 0.9851 | None | 1.0 | D | 0.923 | 0.659 | 0.642306 | gnomAD-4.0.0 | 1.59158E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88879E-05 | 0 | 0 | 0 | 0 |
| P/R | 32897 |
Fn3-128 |
2 | None | 0.9929 | None | 0.999 | D | 0.833 | 0.71 | 0.8100757 | gnomAD-4.0.0 | 1.59389E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86454E-06 | 0 | 0 |
| P/Q | 33291 |
Fn3-130 |
2 | None | 0.9961 | None | 1.0 | D | 0.857 | 0.744 | 0.83210385 | gnomAD-4.0.0 | 1.6557E-06 | None | None | None | None | I | None | 0 | 2.44439E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 33393 |
Fn3-131 |
2 | rs1339535549 |
0.8829 | None | 1.0 | D | 0.826 | 0.568 | 0.79244745 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 33393 |
Fn3-131 |
2 | rs1339535549 |
0.8829 | None | 1.0 | D | 0.826 | 0.568 | 0.79244745 | gnomAD-4.0.0 | 6.57367E-06 | None | None | None | None | N | None | 2.41453E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 33393 |
Fn3-131 |
2 | None | 0.9266 | None | 1.0 | D | 0.757 | 0.564 | 0.46350127 | gnomAD-4.0.0 | 1.49522E-06 | None | None | None | None | N | None | 3.35864E-05 | 3.97078E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 33393 |
Fn3-131 |
2 | None | 0.8528 | None | 1.0 | D | 0.763 | 0.594 | 0.6390076 | gnomAD-4.0.0 | 7.47612E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.45101E-07 | 0 | 0 |
| P/S | 33690 |
Fn3-132 |
2 | None | 0.9906 | None | 1.0 | D | 0.745 | 0.781 | 0.7298364 | gnomAD-4.0.0 | 6.84201E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99447E-07 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.