Structural position:
- Domain Type: Fn3
- Aligned Position: 27
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/R | 15681 |
Fn3-1 |
25 | None | 0.9914 | None | 1.0 | D | 0.879 | 0.651 | 0.601974941769 | gnomAD-4.0.0 | 1.59397E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03141E-05 |
| P/S | 15681 |
Fn3-1 |
25 | rs768557263 |
0.9679 | -2.66 | 1.0 | D | 0.823 | 0.524 | 0.457013227636 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/S | 15681 |
Fn3-1 |
25 | rs768557263 |
0.9679 | -2.66 | 1.0 | D | 0.823 | 0.524 | 0.457013227636 | gnomAD-4.0.0 | 1.59396E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43324E-05 | 0 |
| P/T | 15681 |
Fn3-1 |
25 | None | 0.9575 | None | 1.0 | D | 0.823 | 0.601 | 0.538974603628 | gnomAD-4.0.0 | 1.59396E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86254E-06 | 0 | 0 |
| P/S | 15782 |
Fn3-2 |
25 | rs749192459 |
0.9464 | -2.463 | 1.0 | D | 0.865 | 0.623 | 0.555198480781 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.57E-05 | 0 |
| P/S | 15782 |
Fn3-2 |
25 | rs749192459 |
0.9464 | -2.463 | 1.0 | D | 0.865 | 0.623 | 0.555198480781 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.58E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 15782 |
Fn3-2 |
25 | rs749192459 |
0.9464 | -2.463 | 1.0 | D | 0.865 | 0.623 | 0.555198480781 | gnomAD-4.0.0 | 9.30304E-06 | None | None | None | None | N | None | 0 | 1.67101E-05 | None | 0 | 0 | None | 0 | 0 | 1.18734E-05 | 0 | 0 |
| P/T | 15782 |
Fn3-2 |
25 | rs749192459 |
0.9311 | None | 1.0 | D | 0.861 | 0.699 | 0.633965432156 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 15782 |
Fn3-2 |
25 | rs749192459 |
0.9311 | None | 1.0 | D | 0.861 | 0.699 | 0.633965432156 | gnomAD-4.0.0 | 1.24041E-06 | None | None | None | None | N | None | 1.33672E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.48103E-07 | 0 | 0 |
| P/H | 15883 |
Fn3-3 |
25 | None | 0.9882 | None | 1.0 | D | 0.882 | 0.624 | 0.591878746342 | gnomAD-4.0.0 | 6.92158E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.55245E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/H | 16079 |
Fn3-4 |
25 | None | 0.98 | None | 1.0 | D | 0.859 | 0.638 | 0.610832418033 | gnomAD-4.0.0 | 6.84724E-07 | None | None | None | None | N | None | 0 | 2.23894E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 16079 |
Fn3-4 |
25 | None | 0.981 | None | 1.0 | D | 0.875 | 0.662 | 0.600262279454 | gnomAD-4.0.0 | 6.84724E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00009E-07 | 0 | 0 |
| P/S | 16079 |
Fn3-4 |
25 | rs760271431 |
0.794 | -2.296 | 1.0 | D | 0.825 | 0.51 | 0.472741223727 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
| P/S | 16079 |
Fn3-4 |
25 | rs760271431 |
0.794 | -2.296 | 1.0 | D | 0.825 | 0.51 | 0.472741223727 | gnomAD-4.0.0 | 4.78197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.59102E-06 | 0 | 0 |
| P/L | 16375 |
Fn3-6 |
25 | None | 0.991 | None | 1.0 | D | 0.885 | 0.6 | 0.841995927497 | gnomAD-4.0.0 | 2.73838E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59917E-06 | 0 | 0 |
| P/Q | 16375 |
Fn3-6 |
25 | rs1256813746 |
0.9987 | None | 1.0 | D | 0.812 | 0.627 | 0.73734657789 | gnomAD-4.0.0 | 2.05378E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69938E-06 | 0 | 0 |
| P/R | 16375 |
Fn3-6 |
25 | rs1256813746 |
0.9982 | -1.25 | 1.0 | D | 0.87 | 0.617 | 0.742486130394 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.63E-05 | None | 0 | None | 0 | 0 | 0 |
| P/R | 16375 |
Fn3-6 |
25 | rs1256813746 |
0.9982 | -1.25 | 1.0 | D | 0.87 | 0.617 | 0.742486130394 | gnomAD-4.0.0 | 6.84594E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.53075E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 16375 |
Fn3-6 |
25 | rs1424436024 |
0.9939 | -2.254 | 1.0 | D | 0.833 | 0.525 | 0.482209950775 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| P/L | 16474 |
Fn3-7 |
25 | rs750487328 |
0.9897 | -0.682 | 1.0 | D | 0.901 | 0.599 | 0.899019198802 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| P/L | 16474 |
Fn3-7 |
25 | rs750487328 |
0.9897 | -0.682 | 1.0 | D | 0.901 | 0.599 | 0.899019198802 | gnomAD-4.0.0 | 6.84901E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00067E-07 | 0 | 0 |
| P/R | 16474 |
Fn3-7 |
25 | None | 0.9967 | None | 1.0 | D | 0.894 | 0.598 | 0.844308500322 | gnomAD-4.0.0 | 2.0547E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.32574E-05 | 1.65843E-05 |
| P/S | 16474 |
Fn3-7 |
25 | rs763053848 |
0.9934 | -2.16 | 1.0 | D | 0.869 | 0.534 | 0.616015083648 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| P/S | 16474 |
Fn3-7 |
25 | rs763053848 |
0.9934 | -2.16 | 1.0 | D | 0.869 | 0.534 | 0.616015083648 | gnomAD-4.0.0 | 5.47929E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 9.30189E-05 | 0 |
| P/T | 16474 |
Fn3-7 |
25 | rs763053848 |
0.9876 | -2.019 | 1.0 | D | 0.868 | 0.559 | 0.794095434645 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| P/T | 16474 |
Fn3-7 |
25 | rs763053848 |
0.9876 | -2.019 | 1.0 | D | 0.868 | 0.559 | 0.794095434645 | gnomAD-4.0.0 | 6.84911E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0008E-07 | 0 | 0 |
| P/A | 16575 |
Fn3-8 |
25 | None | 0.9076 | None | 1.0 | D | 0.817 | 0.68 | 0.393775345888 | gnomAD-4.0.0 | 6.8461E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1598E-05 | 0 |
| P/L | 16575 |
Fn3-8 |
25 | None | 0.9819 | None | 1.0 | D | 0.9 | 0.724 | 0.794075965502 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 16575 |
Fn3-8 |
25 | None | 0.9863 | None | 1.0 | D | 0.841 | 0.62 | 0.364141725642 | gnomAD-4.0.0 | 6.8461E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99831E-07 | 0 | 0 |
| P/A | 16775 |
Fn3-10 |
25 | None | 0.9461 | None | 1.0 | D | 0.817 | 0.457 | 0.473538153929 | gnomAD-4.0.0 | 6.8507E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00145E-07 | 0 | 0 |
| P/L | 16775 |
Fn3-10 |
25 | rs1331633157 |
0.9925 | -0.643 | 1.0 | D | 0.894 | 0.489 | 0.695940529277 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.68011E-04 |
| P/L | 16775 |
Fn3-10 |
25 | rs1331633157 |
0.9925 | -0.643 | 1.0 | D | 0.894 | 0.489 | 0.695940529277 | gnomAD-4.0.0 | 3.19195E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86505E-06 | 0 | 3.03435E-05 |
| P/T | 16775 |
Fn3-10 |
25 | None | 0.9922 | None | 1.0 | D | 0.843 | 0.464 | 0.52628473709 | gnomAD-4.0.0 | 6.8507E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.54065E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 17071 |
Fn3-12 |
25 | None | 0.8667 | None | 1.0 | D | 0.808 | 0.632 | 0.484691182572 | gnomAD-4.0.0 | 2.73829E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.525E-05 | None | 0 | 0 | 2.6996E-06 | 0 | 0 |
| P/L | 17071 |
Fn3-12 |
25 | None | 0.9776 | None | 1.0 | D | 0.888 | 0.639 | 0.722483493429 | gnomAD-4.0.0 | 1.59324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4334E-05 | 0 |
| P/L | 17171 |
Fn3-13 |
25 | rs770226870 |
0.9934 | -0.768 | 1.0 | D | 0.893 | 0.685 | 0.910375148093 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| P/L | 17171 |
Fn3-13 |
25 | rs770226870 |
0.9934 | -0.768 | 1.0 | D | 0.893 | 0.685 | 0.910375148093 | gnomAD-4.0.0 | 3.18577E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.5534E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 17171 |
Fn3-13 |
25 | rs773302755 |
0.9928 | -2.79 | 1.0 | D | 0.851 | 0.662 | 0.674262823506 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| P/S | 17171 |
Fn3-13 |
25 | rs773302755 |
0.9928 | -2.79 | 1.0 | D | 0.851 | 0.662 | 0.674262823506 | gnomAD-4.0.0 | 5.47608E-06 | None | None | None | None | N | None | 0 | 6.71081E-05 | None | 0 | 0 | None | 0 | 0 | 4.49901E-06 | 0 | 0 |
| P/L | 17393 |
Fn3-14 |
25 | rs1470469789 |
0.9836 | None | 1.0 | D | 0.89 | 0.706 | 0.723066985631 | gnomAD-4.0.0 | 1.59431E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02902E-05 |
| P/S | 17393 |
Fn3-14 |
25 | rs1481856511 |
0.9863 | None | 1.0 | N | 0.844 | 0.611 | 0.424194796918 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 17393 |
Fn3-14 |
25 | rs1481856511 |
0.9863 | None | 1.0 | N | 0.844 | 0.611 | 0.424194796918 | gnomAD-4.0.0 | 6.58198E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47236E-05 | 0 | 0 |
| P/Q | 17788 |
Fn3-17 |
25 | rs1456305922 |
0.9979 | -1.865 | 1.0 | D | 0.82 | 0.593 | 0.542587012665 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/Q | 17788 |
Fn3-17 |
25 | rs1456305922 |
0.9979 | -1.865 | 1.0 | D | 0.82 | 0.593 | 0.542587012665 | gnomAD-4.0.0 | 3.18626E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86714E-05 | 0 |
| P/S | 18089 |
Fn3-19 |
25 | None | 0.9858 | None | 1.0 | N | 0.837 | 0.642 | 0.367803931526 | gnomAD-4.0.0 | 1.59408E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43439E-05 | 0 |
| P/L | 18603 |
Fn3-23 |
25 | rs531760043 |
0.9832 | -0.599 | 0.996 | D | 0.889 | 0.651 | 0.873394877099 | gnomAD-2.1.1 | 2.09E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.49E-05 | None | 0 | 3.7E-05 | 0 |
| P/L | 18603 |
Fn3-23 |
25 | rs531760043 |
0.9832 | -0.599 | 0.996 | D | 0.889 | 0.651 | 0.873394877099 | gnomAD-4.0.0 | 9.64776E-06 | None | None | None | None | N | None | 0 | 2.2853E-05 | None | 0 | 0 | None | 0 | 0 | 9.94259E-06 | 2.36423E-05 | 0 |
| P/S | 18603 |
Fn3-23 |
25 | None | 0.9775 | None | 0.284 | D | 0.56 | 0.524 | 0.362361684037 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/H | 18809 |
Fn3-24 |
26 | None | 0.9966 | None | 1.0 | D | 0.888 | 0.594 | 0.61690119055 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 18809 |
Fn3-24 |
26 | None | 0.979 | None | 1.0 | N | 0.863 | 0.489 | 0.45235992198 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| P/T | 18809 |
Fn3-24 |
26 | None | 0.9739 | None | 1.0 | N | 0.859 | 0.543 | 0.546131560702 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| P/R | 18908 |
Fn3-25 |
25 | rs1364724756 |
0.9951 | None | 1.0 | D | 0.887 | 0.609 | 0.656961720716 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 18908 |
Fn3-25 |
25 | rs1364724756 |
0.9951 | None | 1.0 | D | 0.887 | 0.609 | 0.656961720716 | gnomAD-4.0.0 | 2.03044E-06 | None | None | None | None | N | None | 1.74978E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20501E-06 | 0 | 0 |
| P/L | 19012 |
Fn3-26 |
25 | rs777291480 |
0.9632 | -0.234 | 1.0 | D | 0.901 | 0.535 | 0.820922146493 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 19012 |
Fn3-26 |
25 | rs777291480 |
0.9632 | -0.234 | 1.0 | D | 0.901 | 0.535 | 0.820922146493 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 19012 |
Fn3-26 |
25 | rs777291480 |
0.9632 | -0.234 | 1.0 | D | 0.901 | 0.535 | 0.820922146493 | gnomAD-4.0.0 | 1.24346E-06 | None | None | None | None | N | None | 1.34311E-05 | 0 | None | 0 | 2.24135E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 19012 |
Fn3-26 |
25 | None | 0.9938 | -1.74 | 1.0 | D | 0.828 | 0.586 | 0.715663011305 | gnomAD-2.1.1 | 1.09E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.58E-05 | 1.42735E-04 |
| P/Q | 19012 |
Fn3-26 |
25 | None | 0.9938 | -1.74 | 1.0 | D | 0.828 | 0.586 | 0.715663011305 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/Q | 19012 |
Fn3-26 |
25 | None | 0.9938 | -1.74 | 1.0 | D | 0.828 | 0.586 | 0.715663011305 | gnomAD-4.0.0 | 8.70425E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01817E-05 | 0 | 3.21182E-05 |
| P/R | 19012 |
Fn3-26 |
25 | rs777291480 |
0.9918 | -1.379 | 1.0 | N | 0.894 | 0.568 | 0.715137123678 | gnomAD-2.1.1 | 1.64E-05 | None | None | None | None | N | None | 0 | 3.01E-05 | None | 0 | 1.15287E-04 | None | 0 | None | 0 | 8.98E-06 | 0 |
| P/R | 19012 |
Fn3-26 |
25 | rs777291480 |
0.9918 | -1.379 | 1.0 | N | 0.894 | 0.568 | 0.715137123678 | gnomAD-4.0.0 | 9.61228E-06 | None | None | None | None | N | None | 0 | 1.14884E-04 | None | 0 | 1.01358E-04 | None | 0 | 0 | 1.80079E-06 | 1.18315E-05 | 3.32325E-05 |
| P/S | 19012 |
Fn3-26 |
25 | None | 0.971 | None | 1.0 | N | 0.842 | 0.472 | 0.445811967706 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| P/L | 19308 |
Fn3-28 |
25 | rs745457069 |
0.9923 | -0.902 | 1.0 | D | 0.907 | 0.534 | 0.739637433589 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 1.20019E-04 | 7.83E-06 | 0 |
| P/L | 19308 |
Fn3-28 |
25 | rs745457069 |
0.9923 | -0.902 | 1.0 | D | 0.907 | 0.534 | 0.739637433589 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/L | 19308 |
Fn3-28 |
25 | rs745457069 |
0.9923 | -0.902 | 1.0 | D | 0.907 | 0.534 | 0.739637433589 | gnomAD-4.0.0 | 1.2822E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.27806E-05 | 0 | 1.43704E-05 | 0 | 0 |
| P/L | 19504 |
Fn3-29 |
26 | rs1454300536 |
0.951 | -0.755 | 1.0 | D | 0.892 | 0.616 | 0.805501000142 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 19504 |
Fn3-29 |
26 | rs1454300536 |
0.951 | -0.755 | 1.0 | D | 0.892 | 0.616 | 0.805501000142 | gnomAD-4.0.0 | 6.84479E-07 | None | None | None | None | N | None | 0 | 2.23964E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 19504 |
Fn3-29 |
26 | None | 0.992 | None | 1.0 | D | 0.882 | 0.635 | 0.678699861113 | gnomAD-4.0.0 | 6.84479E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99591E-07 | 0 | 0 |
| P/L | 20001 |
Fn3-33 |
25 | rs727505345 |
0.9801 | -0.495 | 1.0 | D | 0.911 | 0.543 | None | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 1.55167E-04 | None | 0 | None | 0 | 2.35E-05 | 0 |
| P/L | 20001 |
Fn3-33 |
25 | rs727505345 |
0.9801 | -0.495 | 1.0 | D | 0.911 | 0.543 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 1.94401E-04 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| P/L | 20001 |
Fn3-33 |
25 | rs727505345 |
0.9801 | -0.495 | 1.0 | D | 0.911 | 0.543 | None | gnomAD-4.0.0 | 1.5498E-05 | None | None | None | None | N | None | 5.34231E-05 | 0 | None | 0 | 2.23764E-05 | None | 1.56289E-05 | 0 | 1.52598E-05 | 0 | 1.60164E-05 |
| P/T | 20001 |
Fn3-33 |
25 | None | 0.9714 | None | 1.0 | D | 0.871 | 0.546 | 0.621672535409 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/H | 20196 |
Fn3-34 |
26 | None | 0.9942 | None | 1.0 | D | 0.874 | 0.492 | 0.594452868026 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| P/L | 20295 |
Fn3-35 |
25 | rs1208364622 |
0.9529 | -0.701 | 1.0 | D | 0.921 | 0.604 | 0.832200640711 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| P/L | 20295 |
Fn3-35 |
25 | rs1208364622 |
0.9529 | -0.701 | 1.0 | D | 0.921 | 0.604 | 0.832200640711 | gnomAD-4.0.0 | 1.60757E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4353E-05 | 0 |
| P/R | 20295 |
Fn3-35 |
25 | rs1208364622 |
0.9912 | -1.296 | 1.0 | D | 0.911 | 0.547 | 0.688032785875 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.97E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/R | 20295 |
Fn3-35 |
25 | rs1208364622 |
0.9912 | -1.296 | 1.0 | D | 0.911 | 0.547 | 0.688032785875 | gnomAD-4.0.0 | 1.60757E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.78194E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 20295 |
Fn3-35 |
25 | None | 0.9378 | None | 1.0 | D | 0.896 | 0.551 | 0.594565568268 | gnomAD-4.0.0 | 6.87263E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16109E-05 | 0 |
| P/T | 20295 |
Fn3-35 |
25 | None | 0.9509 | None | 1.0 | D | 0.898 | 0.574 | 0.64273826783 | gnomAD-4.0.0 | 6.87263E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5382E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 20692 |
Fn3-38 |
25 | None | 0.9911 | None | 1.0 | D | 0.849 | 0.574 | 0.755504624012 | gnomAD-4.0.0 | 1.59189E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85933E-06 | 0 | 0 |
| P/Q | 21088 |
Fn3-41 |
25 | None | 0.9948 | None | 1.0 | D | 0.815 | 0.653 | 0.718298551108 | gnomAD-4.0.0 | 1.59881E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88423E-05 | 0 | 0 | 0 | 0 |
| P/S | 21290 |
Fn3-42 |
25 | rs986183406 |
0.9225 | -2.095 | 1.0 | N | 0.827 | 0.484 | 0.45553875121 | gnomAD-2.1.1 | 1.44E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.16E-05 | 0 |
| P/S | 21290 |
Fn3-42 |
25 | rs986183406 |
0.9225 | -2.095 | 1.0 | N | 0.827 | 0.484 | 0.45553875121 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.42E-05 | 0 | 0 |
| P/S | 21290 |
Fn3-42 |
25 | rs986183406 |
0.9225 | -2.095 | 1.0 | N | 0.827 | 0.484 | 0.45553875121 | gnomAD-4.0.0 | 8.06213E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.10235E-05 | 0 | 0 |
| P/A | 21390 |
Fn3-43 |
25 | None | 0.9462 | None | 1.0 | D | 0.813 | 0.586 | 0.581184446821 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 1.94099E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 21390 |
Fn3-43 |
25 | rs763262121 |
0.9912 | -0.718 | 1.0 | D | 0.898 | 0.575 | 0.813234845967 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.34E-05 | 0 |
| P/L | 21390 |
Fn3-43 |
25 | rs763262121 |
0.9912 | -0.718 | 1.0 | D | 0.898 | 0.575 | 0.813234845967 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.78469E-04 |
| P/L | 21390 |
Fn3-43 |
25 | rs763262121 |
0.9912 | -0.718 | 1.0 | D | 0.898 | 0.575 | 0.813234845967 | gnomAD-4.0.0 | 1.28225E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.15597E-05 | 0 | 2.84738E-05 |
| P/S | 21584 |
Fn3-44 |
26 | rs762924797 |
0.9916 | -2.994 | 0.988 | N | 0.802 | 0.463 | 0.51372946856 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/S | 21584 |
Fn3-44 |
26 | rs762924797 |
0.9916 | -2.994 | 0.988 | N | 0.802 | 0.463 | 0.51372946856 | gnomAD-4.0.0 | 1.59223E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| P/T | 21584 |
Fn3-44 |
26 | rs762924797 |
0.9928 | None | 0.988 | D | 0.793 | 0.494 | 0.602613489494 | gnomAD-4.0.0 | 1.59223E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| P/L | 21683 |
Fn3-45 |
25 | rs1328998714 |
0.9747 | None | 1.0 | D | 0.907 | 0.553 | 0.81331731886 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 21683 |
Fn3-45 |
25 | rs1328998714 |
0.9747 | None | 1.0 | D | 0.907 | 0.553 | 0.81331731886 | gnomAD-4.0.0 | 1.2399E-06 | None | None | None | None | N | None | 1.33622E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09815E-05 | 0 |
| P/Q | 21683 |
Fn3-45 |
25 | rs1328998714 |
0.9931 | None | 1.0 | D | 0.859 | 0.548 | 0.669752846865 | gnomAD-4.0.0 | 2.05332E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 3.47464E-04 | 8.99643E-07 | 0 | 0 |
| P/T | 21683 |
Fn3-45 |
25 | rs528707403 |
0.9545 | -2.085 | 1.0 | D | 0.866 | 0.541 | 0.650379344195 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.34E-05 | 0 |
| P/T | 21683 |
Fn3-45 |
25 | rs528707403 |
0.9545 | -2.085 | 1.0 | D | 0.866 | 0.541 | 0.650379344195 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.36E-05 | 0 | 0 |
| P/T | 21683 |
Fn3-45 |
25 | rs528707403 |
0.9545 | -2.085 | 1.0 | D | 0.866 | 0.541 | 0.650379344195 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| P/T | 21683 |
Fn3-45 |
25 | rs528707403 |
0.9545 | -2.085 | 1.0 | D | 0.866 | 0.541 | 0.650379344195 | gnomAD-4.0.0 | 1.35759E-04 | None | None | None | None | N | None | 1.33429E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.82278E-04 | 0 | 4.80446E-05 |
| P/L | 21980 |
Fn3-47 |
25 | None | 0.9859 | None | 1.0 | D | 0.893 | 0.677 | 0.894379702187 | gnomAD-4.0.0 | 1.59316E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86169E-06 | 0 | 0 |
| P/S | 21980 |
Fn3-47 |
25 | None | 0.989 | None | 1.0 | D | 0.837 | 0.617 | 0.591083742983 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/L | 22079 |
Fn3-48 |
25 | rs1379026615 |
0.9809 | None | 1.0 | D | 0.91 | 0.601 | 0.733105195128 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/L | 22079 |
Fn3-48 |
25 | rs1379026615 |
0.9809 | None | 1.0 | D | 0.91 | 0.601 | 0.733105195128 | gnomAD-4.0.0 | 6.41453E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.19724E-05 | 0 | 0 |
| P/S | 22079 |
Fn3-48 |
25 | None | 0.9857 | None | 1.0 | N | 0.873 | 0.489 | 0.459729313489 | gnomAD-4.0.0 | 6.84686E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99656E-07 | 0 | 0 |
| P/T | 22180 |
Fn3-49 |
25 | None | 0.9832 | None | 1.0 | D | 0.851 | 0.746 | 0.635145041397 | gnomAD-4.0.0 | 1.60199E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87429E-06 | 0 | 0 |
| P/Q | 22668 |
Fn3-52 |
26 | rs879160608 |
0.9949 | -1.922 | 1.0 | D | 0.85 | 0.598 | 0.680344662427 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| P/Q | 22668 |
Fn3-52 |
26 | rs879160608 |
0.9949 | -1.922 | 1.0 | D | 0.85 | 0.598 | 0.680344662427 | gnomAD-4.0.0 | 1.36887E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7993E-06 | 0 | 0 |
| P/L | 22767 |
Fn3-53 |
25 | rs775953148 |
0.9558 | -0.757 | 1.0 | D | 0.923 | 0.746 | 0.893768029906 | gnomAD-2.1.1 | 2.84E-05 | None | None | None | None | N | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 4.66E-05 | 4.47E-05 | 0 |
| P/L | 22767 |
Fn3-53 |
25 | rs775953148 |
0.9558 | -0.757 | 1.0 | D | 0.923 | 0.746 | 0.893768029906 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/L | 22767 |
Fn3-53 |
25 | rs775953148 |
0.9558 | -0.757 | 1.0 | D | 0.923 | 0.746 | 0.893768029906 | gnomAD-4.0.0 | 3.16422E-05 | None | None | None | None | N | None | 0 | 3.34303E-05 | None | 0 | 0 | None | 3.12832E-05 | 0 | 3.90163E-05 | 0 | 1.60364E-05 |
| P/R | 22767 |
Fn3-53 |
25 | None | 0.9889 | None | 1.0 | D | 0.914 | 0.794 | 0.814162761347 | gnomAD-4.0.0 | 6.85012E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00075E-07 | 0 | 0 |
| P/T | 22767 |
Fn3-53 |
25 | rs1358490975 |
0.909 | -2.333 | 1.0 | D | 0.883 | 0.719 | 0.747345648389 | gnomAD-2.1.1 | 8.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 9.31E-05 | 0 | 0 |
| P/T | 22767 |
Fn3-53 |
25 | rs1358490975 |
0.909 | -2.333 | 1.0 | D | 0.883 | 0.719 | 0.747345648389 | gnomAD-4.0.0 | 1.5955E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.8843E-05 | 0 | 0 | 0 | 0 |
| P/H | 22865 |
Fn3-54 |
25 | None | 0.9962 | None | 1.0 | D | 0.87 | 0.651 | 0.710313493133 | gnomAD-4.0.0 | 1.60057E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87446E-06 | 0 | 0 |
| P/L | 22865 |
Fn3-54 |
25 | rs1327514162 |
0.9755 | -0.726 | 1.0 | D | 0.892 | 0.7 | 0.831665419939 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| P/L | 22865 |
Fn3-54 |
25 | rs1327514162 |
0.9755 | -0.726 | 1.0 | D | 0.892 | 0.7 | 0.831665419939 | gnomAD-4.0.0 | 6.40229E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.7852E-05 | None | 0 | 0 | 8.62337E-06 | 0 | 0 |
| P/R | 23264 |
Fn3-57 |
25 | None | 0.9939 | None | 1.0 | D | 0.867 | 0.736 | 0.713262185059 | gnomAD-4.0.0 | 2.12756E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.74611E-06 | 0 | 0 |
| P/L | 23459 |
Fn3-58 |
25 | rs776457502 |
0.9835 | -0.247 | 1.0 | D | 0.887 | 0.694 | 0.659120768314 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| P/L | 23459 |
Fn3-58 |
25 | rs776457502 |
0.9835 | -0.247 | 1.0 | D | 0.887 | 0.694 | 0.659120768314 | gnomAD-4.0.0 | 4.79033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29733E-06 | 0 | 0 |
| P/A | 23556 |
Fn3-59 |
25 | rs750670403 |
0.8606 | -2.154 | 1.0 | D | 0.81 | 0.651 | 0.520002024791 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| P/A | 23556 |
Fn3-59 |
25 | rs750670403 |
0.8606 | -2.154 | 1.0 | D | 0.81 | 0.651 | 0.520002024791 | gnomAD-4.0.0 | 6.84277E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52143E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 23556 |
Fn3-59 |
25 | rs1230878552 |
0.9627 | -0.721 | 1.0 | D | 0.903 | 0.665 | 0.802593093059 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| P/L | 23556 |
Fn3-59 |
25 | rs1230878552 |
0.9627 | -0.721 | 1.0 | D | 0.903 | 0.665 | 0.802593093059 | gnomAD-4.0.0 | 1.5916E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85899E-06 | 0 | 0 |
| P/T | 23556 |
Fn3-59 |
25 | rs750670403 |
0.959 | -2.341 | 1.0 | D | 0.83 | 0.691 | 0.580217753726 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23214E-04 | None | 0 | None | 0 | 0 | 0 |
| P/T | 23556 |
Fn3-59 |
25 | rs750670403 |
0.959 | -2.341 | 1.0 | D | 0.83 | 0.691 | 0.580217753726 | gnomAD-4.0.0 | 5.47422E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.01715E-04 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 23850 |
Fn3-61 |
25 | rs996458558 |
0.7787 | None | 1.0 | D | 0.839 | 0.683 | 0.574465425021 | gnomAD-4.0.0 | 4.7903E-06 | None | None | None | None | N | None | 2.98846E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99588E-07 | 0 | 8.28473E-05 |
| P/H | 23948 |
Fn3-62 |
25 | rs762929729 |
0.9927 | -1.573 | 1.0 | D | 0.889 | 0.788 | 0.726553868879 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| P/H | 23948 |
Fn3-62 |
25 | rs762929729 |
0.9927 | -1.573 | 1.0 | D | 0.889 | 0.788 | 0.726553868879 | gnomAD-4.0.0 | 1.59212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85938E-06 | 0 | 0 |
| P/L | 23948 |
Fn3-62 |
25 | None | 0.9377 | None | 1.0 | D | 0.906 | 0.777 | 0.702054141035 | gnomAD-4.0.0 | 1.59212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| P/T | 23948 |
Fn3-62 |
25 | None | 0.9137 | None | 1.0 | D | 0.867 | 0.79 | 0.676191613372 | gnomAD-4.0.0 | 1.59209E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85933E-06 | 0 | 0 |
| P/L | 24347 |
Fn3-65 |
25 | rs762412998 |
0.9877 | -0.238 | 1.0 | D | 0.899 | 0.522 | 0.713372316176 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 2.32113E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 24347 |
Fn3-65 |
25 | rs762412998 |
0.9877 | -0.238 | 1.0 | D | 0.899 | 0.522 | 0.713372316176 | gnomAD-4.0.0 | 9.55454E-06 | None | None | None | None | N | None | 0 | 1.37237E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 24347 |
Fn3-65 |
25 | None | 0.9918 | None | 1.0 | N | 0.86 | 0.491 | 0.411799315854 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 7.32654E-05 |
| P/A | 24543 |
Fn3-66 |
25 | None | 0.8944 | None | 1.0 | D | 0.817 | 0.517 | 0.53129368577 | gnomAD-4.0.0 | 4.8013E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25002E-06 | 0 | 0 |
| P/R | 24543 |
Fn3-66 |
25 | None | 0.9979 | None | 1.0 | D | 0.888 | 0.577 | 0.597153157781 | gnomAD-4.0.0 | 1.59221E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4334E-05 | 0 |
| P/S | 24543 |
Fn3-66 |
25 | rs1277675236 |
0.9811 | None | 1.0 | N | 0.837 | 0.471 | 0.513560046879 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/S | 24543 |
Fn3-66 |
25 | rs1277675236 |
0.9811 | None | 1.0 | N | 0.837 | 0.471 | 0.513560046879 | gnomAD-4.0.0 | 7.10529E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.43475E-06 | 0 | 0 |
| P/T | 24640 |
Fn3-67 |
25 | None | 0.9863 | None | 1.0 | D | 0.837 | 0.679 | 0.608446283964 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85938E-06 | 0 | 0 |
| P/R | 24833 |
Fn3-68 |
26 | None | 0.9941 | None | 1.0 | D | 0.905 | 0.66 | 0.734463599337 | gnomAD-4.0.0 | 1.3688E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99607E-07 | 1.1595E-05 | 0 |
| P/S | 24833 |
Fn3-68 |
26 | rs1251877606 |
0.9771 | None | 1.0 | N | 0.871 | 0.556 | 0.455996456696 | gnomAD-4.0.0 | 6.36918E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56359E-05 | None | 0 | 0 | 5.71925E-06 | 0 | 0 |
| P/A | 24932 |
Fn3-69 |
25 | rs878982463 |
0.8812 | None | 1.0 | D | 0.833 | 0.752 | 0.582924345863 | gnomAD-4.0.0 | 1.77929E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.33898E-05 | 0 | 0 |
| P/S | 24932 |
Fn3-69 |
25 | rs878982463 |
0.9748 | None | 1.0 | D | 0.858 | 0.688 | 0.561065777782 | gnomAD-4.0.0 | 6.84341E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52143E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 25030 |
Fn3-70 |
25 | None | 0.9757 | None | 1.0 | D | 0.895 | 0.762 | 0.919050959195 | gnomAD-4.0.0 | 6.84819E-07 | None | None | None | None | N | None | 2.99133E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 25229 |
Fn3-71 |
26 | rs749230632 |
0.7507 | -2.199 | 1.0 | D | 0.808 | 0.641 | 0.478068462777 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
| P/A | 25229 |
Fn3-71 |
26 | rs749230632 |
0.7507 | -2.199 | 1.0 | D | 0.808 | 0.641 | 0.478068462777 | gnomAD-4.0.0 | 4.1066E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39759E-06 | 0 | 0 |
| P/L | 25229 |
Fn3-71 |
26 | None | 0.9249 | None | 1.0 | D | 0.875 | 0.664 | 0.585836789056 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 25229 |
Fn3-71 |
26 | rs749230632 |
0.9454 | None | 1.0 | N | 0.817 | 0.544 | 0.442775082573 | gnomAD-4.0.0 | 1.36887E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7992E-06 | 0 | 0 |
| P/L | 25328 |
Fn3-72 |
25 | rs758581188 |
0.9655 | -0.795 | 1.0 | D | 0.937 | 0.696 | 0.850381006097 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| P/L | 25328 |
Fn3-72 |
25 | rs758581188 |
0.9655 | -0.795 | 1.0 | D | 0.937 | 0.696 | 0.850381006097 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/L | 25328 |
Fn3-72 |
25 | rs758581188 |
0.9655 | -0.795 | 1.0 | D | 0.937 | 0.696 | 0.850381006097 | gnomAD-4.0.0 | 3.84299E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25597E-05 | 0 | 0 |
| P/S | 25328 |
Fn3-72 |
25 | rs201776072 |
0.9803 | -2.406 | 1.0 | D | 0.911 | 0.629 | 0.612736520223 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/S | 25328 |
Fn3-72 |
25 | rs201776072 |
0.9803 | -2.406 | 1.0 | D | 0.911 | 0.629 | 0.612736520223 | gnomAD-4.0.0 | 6.84309E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1595E-05 | 0 |
| P/T | 25328 |
Fn3-72 |
25 | rs201776072 |
0.9743 | -2.089 | 1.0 | D | 0.913 | 0.684 | 0.657750020267 | gnomAD-2.1.1 | 8.06E-05 | None | None | None | None | N | None | 0 | 5.80215E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 25328 |
Fn3-72 |
25 | rs201776072 |
0.9743 | -2.089 | 1.0 | D | 0.913 | 0.684 | 0.657750020267 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 25328 |
Fn3-72 |
25 | rs201776072 |
0.9743 | -2.089 | 1.0 | D | 0.913 | 0.684 | 0.657750020267 | gnomAD-4.0.0 | 1.36365E-05 | None | None | None | None | N | None | 0 | 3.50198E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60159E-05 |
| P/R | 25429 |
Fn3-73 |
25 | None | 0.9972 | None | 1.0 | D | 0.901 | 0.696 | 0.86290857626 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/T | 25429 |
Fn3-73 |
25 | rs1707494273 |
0.982 | None | 1.0 | D | 0.869 | 0.696 | 0.815910387833 | gnomAD-4.0.0 | 1.59191E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77593E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 25722 |
Fn3-75 |
25 | rs776432275 |
0.9089 | -2.239 | 1.0 | D | 0.831 | 0.717 | 0.541015953236 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/A | 25722 |
Fn3-75 |
25 | rs776432275 |
0.9089 | -2.239 | 1.0 | D | 0.831 | 0.717 | 0.541015953236 | gnomAD-4.0.0 | 1.59205E-06 | None | None | None | None | N | None | 0 | 2.28645E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 25722 |
Fn3-75 |
25 | None | 0.9808 | -2.472 | 1.0 | D | 0.863 | 0.768 | 0.601816880433 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 25722 |
Fn3-75 |
25 | None | 0.9808 | -2.472 | 1.0 | D | 0.863 | 0.768 | 0.601816880433 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 25722 |
Fn3-75 |
25 | None | 0.9808 | -2.472 | 1.0 | D | 0.863 | 0.768 | 0.601816880433 | gnomAD-4.0.0 | 6.5786E-06 | None | None | None | None | N | None | 2.41453E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 26014 |
Fn3-77 |
25 | rs766846103 |
0.974 | -0.934 | 1.0 | D | 0.875 | 0.737 | 0.916481694761 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
| P/L | 26014 |
Fn3-77 |
25 | rs766846103 |
0.974 | -0.934 | 1.0 | D | 0.875 | 0.737 | 0.916481694761 | gnomAD-4.0.0 | 8.21237E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99594E-06 | 0 | 3.31433E-05 |
| P/Q | 26014 |
Fn3-77 |
25 | rs766846103 |
0.9969 | None | 1.0 | D | 0.809 | 0.755 | 0.814192286201 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/Q | 26014 |
Fn3-77 |
25 | rs766846103 |
0.9969 | None | 1.0 | D | 0.809 | 0.755 | 0.814192286201 | gnomAD-4.0.0 | 6.57739E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47115E-05 | 0 | 0 |
| P/T | 26014 |
Fn3-77 |
25 | rs751646451 |
0.9736 | -1.939 | 1.0 | D | 0.821 | 0.724 | 0.798483297613 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| P/T | 26014 |
Fn3-77 |
25 | rs751646451 |
0.9736 | -1.939 | 1.0 | D | 0.821 | 0.724 | 0.798483297613 | gnomAD-4.0.0 | 1.59201E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77716E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 26112 |
Fn3-78 |
25 | None | 0.9966 | None | 1.0 | D | 0.887 | 0.764 | 0.879588553196 | gnomAD-4.0.0 | 1.59192E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85958E-06 | 0 | 0 |
| P/T | 26112 |
Fn3-78 |
25 | None | 0.979 | None | 1.0 | D | 0.85 | 0.737 | 0.835049036447 | gnomAD-4.0.0 | 1.36864E-06 | None | None | None | None | N | None | 2.99007E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1595E-05 | 0 |
| P/L | 26311 |
Fn3-79 |
26 | None | 0.9713 | None | 1.0 | D | 0.903 | 0.714 | 0.831421814805 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| P/S | 26311 |
Fn3-79 |
26 | rs888575364 |
0.9747 | -2.493 | 1.0 | N | 0.856 | 0.589 | 0.44307954383 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| P/S | 26311 |
Fn3-79 |
26 | rs888575364 |
0.9747 | -2.493 | 1.0 | N | 0.856 | 0.589 | 0.44307954383 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 26311 |
Fn3-79 |
26 | rs888575364 |
0.9747 | -2.493 | 1.0 | N | 0.856 | 0.589 | 0.44307954383 | gnomAD-4.0.0 | 4.342E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93756E-06 | 0 | 0 |
| P/R | 26410 |
Fn3-80 |
25 | None | 0.9975 | None | 1.0 | D | 0.889 | 0.736 | 0.669250944419 | gnomAD-4.0.0 | 1.59173E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02554E-05 |
| P/S | 26410 |
Fn3-80 |
25 | None | 0.9903 | None | 1.0 | D | 0.861 | 0.68 | 0.581534369529 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 26511 |
Fn3-81 |
25 | rs1298988924 |
0.9752 | -0.6 | 1.0 | D | 0.897 | 0.766 | 0.91646365068 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.02512E-04 | None | 0 | None | 0 | 0 | 0 |
| P/L | 26511 |
Fn3-81 |
25 | rs1298988924 |
0.9752 | -0.6 | 1.0 | D | 0.897 | 0.766 | 0.91646365068 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93349E-04 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 26511 |
Fn3-81 |
25 | rs1298988924 |
0.9752 | -0.6 | 1.0 | D | 0.897 | 0.766 | 0.91646365068 | gnomAD-4.0.0 | 1.24042E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.45831E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 26707 |
Fn3-82 |
25 | None | 0.9714 | None | 1.0 | D | 0.872 | 0.7 | 0.769475359402 | gnomAD-4.0.0 | 1.59183E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85948E-06 | 0 | 0 |
| P/T | 26707 |
Fn3-82 |
25 | None | 0.9635 | None | 1.0 | D | 0.819 | 0.703 | None | gnomAD-4.0.0 | 1.59184E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85954E-06 | 0 | 0 |
| P/R | 26804 |
Fn3-83 |
25 | rs1299301898 |
0.994 | -1.24 | 1.0 | D | 0.883 | 0.762 | 0.664580999671 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/R | 26804 |
Fn3-83 |
25 | rs1299301898 |
0.994 | -1.24 | 1.0 | D | 0.883 | 0.762 | 0.664580999671 | gnomAD-4.0.0 | 1.59166E-06 | None | None | None | None | N | None | 0 | 2.28645E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 26804 |
Fn3-83 |
25 | None | 0.9614 | None | 1.0 | D | 0.834 | 0.738 | 0.604738496201 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/S | 27394 |
Fn3-87 |
26 | None | 0.938 | None | 1.0 | D | 0.857 | 0.48 | 0.57803241275 | gnomAD-4.0.0 | 3.18284E-06 | None | None | None | None | N | None | 5.65675E-05 | 0 | None | 0 | 0 | None | 1.88232E-05 | 0 | 0 | 0 | 0 |
| P/T | 27394 |
Fn3-87 |
26 | None | 0.9308 | None | 1.0 | D | 0.855 | 0.5 | 0.631643887469 | gnomAD-4.0.0 | 3.18284E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71732E-06 | 0 | 0 |
| P/S | 27790 |
Fn3-90 |
25 | rs1427845923 |
0.9718 | -2.489 | 1.0 | N | 0.822 | 0.628 | 0.463157528383 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/S | 27790 |
Fn3-90 |
25 | rs1427845923 |
0.9718 | -2.489 | 1.0 | N | 0.822 | 0.628 | 0.463157528383 | gnomAD-4.0.0 | 4.79146E-06 | None | None | None | None | N | None | 2.99133E-05 | 2.23854E-05 | None | 0 | 0 | None | 0 | 0 | 3.59859E-06 | 1.15999E-05 | 0 |
| P/Q | 27887 |
Fn3-91 |
25 | rs751121559 |
0.9937 | -2.153 | 1.0 | D | 0.843 | 0.681 | None | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| P/Q | 27887 |
Fn3-91 |
25 | rs751121559 |
0.9937 | -2.153 | 1.0 | D | 0.843 | 0.681 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/Q | 27887 |
Fn3-91 |
25 | rs751121559 |
0.9937 | -2.153 | 1.0 | D | 0.843 | 0.681 | None | gnomAD-4.0.0 | 6.19908E-06 | None | None | None | None | N | None | 0 | 1.66845E-05 | None | 0 | 0 | None | 0 | 0 | 7.62967E-06 | 0 | 0 |
| P/T | 28178 |
Fn3-93 |
25 | None | 0.9776 | None | 1.0 | D | 0.855 | 0.711 | 0.77169317571 | gnomAD-4.0.0 | 1.36906E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7994E-06 | 0 | 0 |
| P/L | 28276 |
Fn3-94 |
25 | None | 0.9613 | None | 1.0 | D | 0.916 | 0.692 | 0.729455935219 | gnomAD-4.0.0 | 1.59123E-06 | None | None | None | None | N | None | 5.65483E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 28475 |
Fn3-95 |
26 | None | 0.7363 | None | 0.978 | D | 0.881 | 0.562 | 0.891450760401 | gnomAD-4.0.0 | 2.73718E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59787E-06 | 0 | 0 |
| P/S | 28574 |
Fn3-96 |
25 | None | 0.9466 | None | 0.568 | N | 0.553 | 0.466 | 0.304108284078 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| P/L | 28675 |
Fn3-97 |
25 | rs766419568 |
0.9749 | -0.744 | 1.0 | D | 0.885 | 0.554 | 0.87202896623 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.72E-05 | 0 |
| P/L | 28675 |
Fn3-97 |
25 | rs766419568 |
0.9749 | -0.744 | 1.0 | D | 0.885 | 0.554 | 0.87202896623 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| P/L | 28675 |
Fn3-97 |
25 | rs766419568 |
0.9749 | -0.744 | 1.0 | D | 0.885 | 0.554 | 0.87202896623 | gnomAD-4.0.0 | 6.25936E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.4764E-05 | 1.09806E-05 | 0 |
| P/Q | 28675 |
Fn3-97 |
25 | rs766419568 |
0.9922 | -2.028 | 1.0 | D | 0.811 | 0.557 | 0.697046195919 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14837E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/Q | 28675 |
Fn3-97 |
25 | rs766419568 |
0.9922 | -2.028 | 1.0 | D | 0.811 | 0.557 | 0.697046195919 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/Q | 28675 |
Fn3-97 |
25 | rs766419568 |
0.9922 | -2.028 | 1.0 | D | 0.811 | 0.557 | 0.697046195919 | gnomAD-4.0.0 | 6.58042E-06 | None | None | None | None | N | None | 2.41558E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 28869 |
Fn3-98 |
25 | None | 0.9908 | None | 1.0 | D | 0.881 | 0.62 | 0.703389443201 | gnomAD-4.0.0 | 1.59134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02425E-05 |
| P/S | 28869 |
Fn3-98 |
25 | rs1702825954 |
0.9448 | None | 1.0 | N | 0.839 | 0.505 | 0.417586769301 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 28869 |
Fn3-98 |
25 | rs1702825954 |
0.9448 | None | 1.0 | N | 0.839 | 0.505 | 0.417586769301 | gnomAD-4.0.0 | 6.57229E-06 | None | None | None | None | N | None | 2.41348E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 28966 |
Fn3-99 |
25 | None | 0.8537 | None | 1.0 | D | 0.825 | 0.692 | 0.622259118589 | gnomAD-4.0.0 | 1.59145E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8582E-06 | 0 | 0 |
| P/S | 28966 |
Fn3-99 |
25 | rs1216201291 |
0.9723 | -2.679 | 1.0 | D | 0.855 | 0.637 | 0.584086171949 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 1.16056E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/S | 28966 |
Fn3-99 |
25 | rs1216201291 |
0.9723 | -2.679 | 1.0 | D | 0.855 | 0.637 | 0.584086171949 | gnomAD-4.0.0 | 6.3658E-06 | None | None | None | None | N | None | 0 | 9.14578E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 29162 |
Fn3-100 |
26 | rs1396243813 |
0.9893 | None | 1.0 | D | 0.893 | 0.71 | 0.582670042736 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 29162 |
Fn3-100 |
26 | rs1396243813 |
0.9893 | None | 1.0 | D | 0.893 | 0.71 | 0.582670042736 | gnomAD-4.0.0 | 2.56203E-06 | None | None | None | None | N | None | 1.6913E-05 | 0 | None | 0 | 2.42354E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 29162 |
Fn3-100 |
26 | None | 0.9567 | None | 1.0 | D | 0.85 | 0.621 | 0.530655398971 | gnomAD-4.0.0 | 2.7368E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.8754E-05 | 0 | 2.69828E-06 | 0 | 0 |
| P/T | 29261 |
Fn3-101 |
25 | None | 0.9601 | None | 1.0 | D | 0.855 | 0.697 | 0.796983491231 | gnomAD-4.0.0 | 1.59108E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| P/L | 29558 |
Fn3-103 |
26 | rs1438123245 |
0.8256 | -0.677 | 1.0 | D | 0.897 | 0.597 | 0.737052393128 | gnomAD-2.1.1 | 7.14E-06 | None | None | None | None | N | None | 8.26E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 29558 |
Fn3-103 |
26 | rs1438123245 |
0.8256 | -0.677 | 1.0 | D | 0.897 | 0.597 | 0.737052393128 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 29558 |
Fn3-103 |
26 | rs1438123245 |
0.8256 | -0.677 | 1.0 | D | 0.897 | 0.597 | 0.737052393128 | gnomAD-4.0.0 | 3.84273E-06 | None | None | None | None | N | None | 5.0734E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 29657 |
Fn3-104 |
25 | rs1700388515 |
0.9679 | None | 1.0 | D | 0.847 | 0.669 | 0.610467662648 | gnomAD-4.0.0 | 6.84252E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99471E-07 | 0 | 0 |
| P/T | 29957 |
Fn3-106 |
25 | rs1164517962 |
0.98 | -2.12 | 0.978 | D | 0.811 | 0.642 | 0.631129199617 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| P/T | 29957 |
Fn3-106 |
25 | rs1164517962 |
0.98 | -2.12 | 0.978 | D | 0.811 | 0.642 | 0.631129199617 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/T | 29957 |
Fn3-106 |
25 | rs1164517962 |
0.98 | -2.12 | 0.978 | D | 0.811 | 0.642 | 0.631129199617 | gnomAD-4.0.0 | 1.92349E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62765E-05 | 0 | 0 |
| P/L | 30054 |
Fn3-107 |
25 | rs767891763 |
0.9797 | -0.759 | 1.0 | D | 0.903 | 0.571 | 0.740784487212 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| P/L | 30054 |
Fn3-107 |
25 | rs767891763 |
0.9797 | -0.759 | 1.0 | D | 0.903 | 0.571 | 0.740784487212 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 30054 |
Fn3-107 |
25 | rs767891763 |
0.9797 | -0.759 | 1.0 | D | 0.903 | 0.571 | 0.740784487212 | gnomAD-4.0.0 | 1.9209E-05 | None | None | None | None | N | None | 1.33454E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54271E-05 | 0 | 0 |
| P/R | 30054 |
Fn3-107 |
25 | None | 0.9945 | None | 1.0 | D | 0.893 | 0.622 | 0.563173181975 | gnomAD-4.0.0 | 6.84169E-07 | None | None | None | None | N | None | 0 | 2.23604E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 30249 |
Fn3-108 |
26 | rs751971702 |
0.8383 | -1.821 | 1.0 | D | 0.787 | 0.69 | 0.593798965771 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| P/A | 30249 |
Fn3-108 |
26 | rs751971702 |
0.8383 | -1.821 | 1.0 | D | 0.787 | 0.69 | 0.593798965771 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/A | 30249 |
Fn3-108 |
26 | rs751971702 |
0.8383 | -1.821 | 1.0 | D | 0.787 | 0.69 | 0.593798965771 | gnomAD-4.0.0 | 1.8593E-06 | None | None | None | None | N | None | 1.33615E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69523E-06 | 0 | 0 |
| P/S | 30249 |
Fn3-108 |
26 | None | 0.9723 | None | 1.0 | D | 0.803 | 0.628 | 0.582356428975 | gnomAD-4.0.0 | 6.84209E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15966E-05 | 0 |
| P/L | 30348 |
Fn3-109 |
25 | rs1465887824 |
0.8771 | -0.583 | 1.0 | D | 0.887 | 0.631 | 0.841468654952 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| P/L | 30348 |
Fn3-109 |
25 | rs1465887824 |
0.8771 | -0.583 | 1.0 | D | 0.887 | 0.631 | 0.841468654952 | gnomAD-4.0.0 | 3.18218E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88239E-05 | 0 | 2.85793E-06 | 0 | 0 |
| P/S | 30348 |
Fn3-109 |
25 | rs746285549 |
0.8205 | -1.871 | 1.0 | N | 0.823 | 0.632 | 0.427940940899 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| P/S | 30348 |
Fn3-109 |
25 | rs746285549 |
0.8205 | -1.871 | 1.0 | N | 0.823 | 0.632 | 0.427940940899 | gnomAD-4.0.0 | 6.84183E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99449E-07 | 0 | 0 |
| P/T | 30348 |
Fn3-109 |
25 | None | 0.8253 | None | 1.0 | D | 0.818 | 0.701 | 0.651931416193 | gnomAD-4.0.0 | 2.05255E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69835E-06 | 0 | 0 |
| P/L | 30446 |
Fn3-110 |
25 | rs1699285500 |
0.979 | None | 1.0 | D | 0.9 | 0.612 | 0.87861949169 | gnomAD-4.0.0 | 1.09491E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25939E-05 | 0 | 3.31367E-05 |
| P/R | 30743 |
Fn3-112 |
25 | rs771621337 |
0.995 | -0.906 | 1.0 | D | 0.908 | 0.731 | 0.829251667788 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| P/R | 30743 |
Fn3-112 |
25 | rs771621337 |
0.995 | -0.906 | 1.0 | D | 0.908 | 0.731 | 0.829251667788 | gnomAD-4.0.0 | 3.18291E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41313E-04 | 2.85843E-06 | 0 | 0 |
| P/L | 30845 |
Fn3-113 |
25 | rs776489830 |
0.9408 | -0.68 | 1.0 | D | 0.896 | 0.836 | 0.916646520119 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/L | 30845 |
Fn3-113 |
25 | rs776489830 |
0.9408 | -0.68 | 1.0 | D | 0.896 | 0.836 | 0.916646520119 | gnomAD-4.0.0 | 3.0984E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23786E-06 | 0 | 0 |
| P/S | 30845 |
Fn3-113 |
25 | rs1314867474 |
0.9405 | None | 1.0 | D | 0.864 | 0.797 | 0.664918217258 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 30845 |
Fn3-113 |
25 | rs1314867474 |
0.9405 | None | 1.0 | D | 0.864 | 0.797 | 0.664918217258 | gnomAD-4.0.0 | 6.57479E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47016E-05 | 0 | 0 |
| P/T | 31137 |
Fn3-115 |
25 | None | 0.968 | None | 0.998 | D | 0.785 | 0.709 | 0.572452295634 | gnomAD-4.0.0 | 3.42089E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49722E-06 | 0 | 0 |
| P/L | 31333 |
Fn3-116 |
26 | None | 0.8921 | None | 1.0 | D | 0.909 | 0.519 | 0.665058716224 | gnomAD-4.0.0 | 1.5911E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85804E-06 | 0 | 0 |
| P/S | 31333 |
Fn3-116 |
26 | None | 0.8946 | None | 1.0 | N | 0.857 | 0.449 | 0.421674004627 | gnomAD-4.0.0 | 3.1822E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85804E-06 | 1.43271E-05 | 0 |
| P/L | 31432 |
Fn3-117 |
25 | rs759415579 |
0.9763 | -0.488 | 1.0 | D | 0.898 | 0.62 | 0.904311493753 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.61472E-04 | None | 0 | 0 | 0 |
| P/L | 31432 |
Fn3-117 |
25 | rs759415579 |
0.9763 | -0.488 | 1.0 | D | 0.898 | 0.62 | 0.904311493753 | gnomAD-4.0.0 | 1.43685E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31879E-04 | 1.65662E-05 |
| P/L | 31732 |
Fn3-119 |
25 | rs753334568 |
0.9061 | -0.671 | 1.0 | D | 0.888 | 0.727 | 0.908895312635 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.78E-05 | 0 |
| P/L | 31732 |
Fn3-119 |
25 | rs753334568 |
0.9061 | -0.671 | 1.0 | D | 0.888 | 0.727 | 0.908895312635 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/L | 31732 |
Fn3-119 |
25 | rs753334568 |
0.9061 | -0.671 | 1.0 | D | 0.888 | 0.727 | 0.908895312635 |
Vasli (2012)
Pfeffer (2013)
Palmio (2013)
Hedberg (2014)
Yue (2015)
Rees (2021)
Sano (2022)
| None |
CM
HMERF
|
hom / comp het with R34091W | None | None | N | Incomplete penetrance, more severe when homozygous; Found in genetic analysis of TTN in 30 CM patients (homozygous); genetic analysis of genes in 127 undiagnosed patients (likely MFM); WES/WGS prioritisation in 12 HMERF families; genetic analysis in single NMD patient (heterozygous); genetic analysis of CN patient (sporadic) and unaffected carrier (brother); Domain unfolded in vitro (Tm 17 degrees lower than WT) | None | None | None | None | None | None | None | None | None | None | None |
| P/L | 31732 |
Fn3-119 |
25 | rs753334568 |
0.9061 | -0.671 | 1.0 | D | 0.888 | 0.727 | 0.908895312635 | gnomAD-4.0.0 | 9.29582E-06 | None | None | None | None | N | None | 0 | 1.66706E-05 | None | 0 | 0 | None | 0 | 0 | 1.01715E-05 | 1.09786E-05 | 1.60123E-05 |
| P/R | 31732 |
Fn3-119 |
25 | None | 0.9881 | None | 1.0 | D | 0.879 | 0.764 | 0.817229753402 | gnomAD-4.0.0 | 6.84245E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| P/A | 31933 |
Fn3-121 |
25 | None | 0.7881 | None | 1.0 | D | 0.831 | 0.552 | 0.656232129661 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| P/S | 32226 |
Fn3-123 |
25 | rs1060500595 |
0.9219 | None | 1.0 | D | 0.823 | 0.697 | 0.5343833383 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 32226 |
Fn3-123 |
25 | rs1060500595 |
0.9219 | None | 1.0 | D | 0.823 | 0.697 | 0.5343833383 | gnomAD-4.0.0 | 6.57531E-06 | None | None | None | None | N | None | 2.41371E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 32226 |
Fn3-123 |
25 | rs1060500595 |
0.9088 | -2.142 | 1.0 | D | 0.821 | 0.74 | 0.606135397127 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| P/T | 32226 |
Fn3-123 |
25 | rs1060500595 |
0.9088 | -2.142 | 1.0 | D | 0.821 | 0.74 | 0.606135397127 | gnomAD-4.0.0 | 1.59112E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77269E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 32424 |
Fn3-124 |
26 | None | 0.9863 | None | 0.085 | D | 0.683 | 0.657 | 0.679066282414 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/Q | 32523 |
Fn3-125 |
25 | None | 0.9613 | None | 1.0 | D | 0.817 | 0.685 | 0.6697384959 | gnomAD-4.0.0 | 1.36895E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79939E-06 | 0 | 0 |
| P/R | 32523 |
Fn3-125 |
25 | rs1406600321 |
0.962 | -1.254 | 1.0 | D | 0.874 | 0.694 | 0.7057210436 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| P/R | 32523 |
Fn3-125 |
25 | rs1406600321 |
0.962 | -1.254 | 1.0 | D | 0.874 | 0.694 | 0.7057210436 | gnomAD-4.0.0 | 6.84473E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99696E-07 | 0 | 0 |
| P/S | 32820 |
Fn3-127 |
26 | rs769919302 |
0.9035 | -1.948 | 1.0 | D | 0.833 | 0.651 | 0.651299431776 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| P/S | 32820 |
Fn3-127 |
26 | rs769919302 |
0.9035 | -1.948 | 1.0 | D | 0.833 | 0.651 | 0.651299431776 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 32820 |
Fn3-127 |
26 | rs769919302 |
0.9035 | -1.948 | 1.0 | D | 0.833 | 0.651 | 0.651299431776 | gnomAD-4.0.0 | 8.9673E-06 | None | None | None | None | N | None | 1.69193E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.43576E-05 | 0 | 0 |
| P/L | 33022 |
Fn3-129 |
25 | rs987137780 |
0.964 | -0.77 | 1.0 | D | 0.921 | 0.621 | 0.806718744816 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| P/L | 33022 |
Fn3-129 |
25 | rs987137780 |
0.964 | -0.77 | 1.0 | D | 0.921 | 0.621 | 0.806718744816 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| P/L | 33022 |
Fn3-129 |
25 | rs987137780 |
0.964 | -0.77 | 1.0 | D | 0.921 | 0.621 | 0.806718744816 | gnomAD-4.0.0 | 6.19783E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47673E-06 | 0 | 0 |
| P/T | 33022 |
Fn3-129 |
25 | rs779645034 |
0.9401 | -2.023 | 1.0 | D | 0.858 | 0.624 | 0.628675003835 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/T | 33022 |
Fn3-129 |
25 | rs779645034 |
0.9401 | -2.023 | 1.0 | D | 0.858 | 0.624 | 0.628675003835 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 33022 |
Fn3-129 |
25 | rs779645034 |
0.9401 | -2.023 | 1.0 | D | 0.858 | 0.624 | 0.628675003835 | gnomAD-4.0.0 | 1.23958E-06 | None | None | None | None | N | None | 1.33586E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09808E-05 | 0 |
| P/T | 33315 |
Fn3-130 |
26 | rs1401105733 |
0.9577 | -2.039 | 0.998 | D | 0.803 | 0.529 | 0.51230852224 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 33315 |
Fn3-130 |
26 | rs1401105733 |
0.9577 | -2.039 | 0.998 | D | 0.803 | 0.529 | 0.51230852224 | gnomAD-4.0.0 | 1.5916E-06 | None | None | None | None | N | None | 5.65867E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 33416 |
Fn3-131 |
25 | None | 0.8862 | None | 1.0 | D | 0.849 | 0.634 | 0.576080139486 | gnomAD-4.0.0 | 1.73458E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.70103E-05 | 0 |
| P/T | 33416 |
Fn3-131 |
25 | rs1691567099 |
0.8602 | None | 1.0 | D | 0.846 | 0.686 | 0.627645487632 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 33713 |
Fn3-132 |
25 | None | 0.6966 | None | 0.04 | N | 0.508 | 0.589 | 0.309530620856 | gnomAD-4.0.0 | 6.84208E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9945E-07 | 0 | 0 |
| P/L | 33713 |
Fn3-132 |
25 | rs1317049640 |
0.9501 | -0.771 | 0.997 | D | 0.872 | 0.677 | 0.767357779069 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| P/L | 33713 |
Fn3-132 |
25 | rs1317049640 |
0.9501 | -0.771 | 0.997 | D | 0.872 | 0.677 | 0.767357779069 | gnomAD-4.0.0 | 2.0526E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69834E-06 | 0 | 0 |
| P/S | 33713 |
Fn3-132 |
25 | None | 0.9482 | None | 0.988 | N | 0.765 | 0.637 | 0.438383285633 | gnomAD-4.0.0 | 6.84208E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9945E-07 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.