Structural position:

  • Domain Type: Fn3
  • Aligned Position: 34
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
E/A 15789 Fn3-2 32 None 0.1005 None 0.201 N 0.425 0.112 0.236890367714 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/D 15789 Fn3-2 32 None 0.1186 None 0.549 N 0.361 0.1 0.211220785272 gnomAD-4.0.0 1.59351E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02957E-05
E/K 15789 Fn3-2 32 None 0.1018 None 0.549 N 0.379 0.161 0.289474373501 gnomAD-4.0.0 1.09541E-05 None None None None I None 0 0 None 0 0 None 0 0 1.43983E-05 0 0
E/Q 15789 Fn3-2 32 rs755290030 0.114 0.29 0.712 N 0.408 0.122 0.227260227426 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
E/Q 15789 Fn3-2 32 rs755290030 0.114 0.29 0.712 N 0.408 0.122 0.227260227426 gnomAD-4.0.0 6.8463E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.15972E-05 0
P/L 16086 Fn3-4 32 rs567496224 0.1176 -0.02 1.0 D 0.724 0.446 0.665643713772 gnomAD-2.1.1 8.07E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 8.93E-06 0
P/L 16086 Fn3-4 32 rs567496224 0.1176 -0.02 1.0 D 0.724 0.446 0.665643713772 gnomAD-3.1.2 6.59E-06 None None None None I None 0 6.58E-05 0 0 0 None 0 0 0 0 0
P/L 16086 Fn3-4 32 rs567496224 0.1176 -0.02 1.0 D 0.724 0.446 0.665643713772 1000 genomes 1.99681E-04 None None None None I None 0 1.4E-03 None None 0 0 None None None 0 None
P/L 16086 Fn3-4 32 rs567496224 0.1176 -0.02 1.0 D 0.724 0.446 0.665643713772 gnomAD-4.0.0 2.17098E-05 None None None None I None 0 3.33934E-05 None 0 0 None 0 0 2.54473E-05 1.09895E-05 3.20585E-05
R/C 16186 Fn3-5 32 rs377563403 0.2486 -0.044 1.0 N 0.445 0.396 0.556145022309 gnomAD-2.1.1 8.46E-05 None None None None I None 1.2945E-04 2.9E-05 None 0 0 None 5.23115E-04 None 0 1.78E-05 0
R/C 16186 Fn3-5 32 rs377563403 0.2486 -0.044 1.0 N 0.445 0.396 0.556145022309 gnomAD-3.1.2 3.95E-05 None None None None I None 9.67E-05 0 0 0 0 None 0 0 0 4.14766E-04 0
R/C 16186 Fn3-5 32 rs377563403 0.2486 -0.044 1.0 N 0.445 0.396 0.556145022309 gnomAD-4.0.0 3.59688E-05 None None None None I None 6.67735E-05 0 None 0 0 None 0 0 8.48151E-06 4.72413E-04 0
R/H 16186 Fn3-5 32 rs769784536 0.1344 -0.687 0.999 N 0.437 0.288 0.233150807113 gnomAD-2.1.1 2.01E-05 None None None None I None 0 0 None 0 0 None 6.54E-05 None 0 1.78E-05 1.66279E-04
R/H 16186 Fn3-5 32 rs769784536 0.1344 -0.687 0.999 N 0.437 0.288 0.233150807113 gnomAD-3.1.2 2.63E-05 None None None None I None 2.42E-05 0 0 0 0 None 9.42E-05 0 0 4.1511E-04 0
R/H 16186 Fn3-5 32 rs769784536 0.1344 -0.687 0.999 N 0.437 0.288 0.233150807113 gnomAD-4.0.0 2.17058E-05 None None None None I None 1.33715E-05 0 None 0 0 None 1.56206E-05 0 2.03551E-05 8.78908E-05 1.60272E-05
R/L 16186 Fn3-5 32 rs769784536 0.3006 0.531 0.983 N 0.56 0.276 0.515317749148 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 5.59E-05 None 0 None 0 0 0
R/L 16186 Fn3-5 32 rs769784536 0.3006 0.531 0.983 N 0.56 0.276 0.515317749148 gnomAD-3.1.2 1.98E-05 None None None None I None 0 1.97006E-04 0 0 0 None 0 0 0 0 0
R/L 16186 Fn3-5 32 rs769784536 0.3006 0.531 0.983 N 0.56 0.276 0.515317749148 gnomAD-4.0.0 6.20167E-06 None None None None I None 0 5.00734E-05 None 0 2.23484E-05 None 0 0 2.54439E-06 0 4.80815E-05
R/S 16186 Fn3-5 32 rs377563403 0.5552 None 0.533 N 0.22 0.136 None gnomAD-3.1.2 6.59E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
R/S 16186 Fn3-5 32 rs377563403 0.5552 None 0.533 N 0.22 0.136 None gnomAD-4.0.0 1.86059E-06 None None None None I None 2.6753E-05 0 None 0 0 None 0 0 8.48145E-07 0 0
K/R 16382 Fn3-6 32 None 0.0869 None 0.135 N 0.193 0.052 0.245660935333 gnomAD-4.0.0 2.73848E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69935E-06 0 1.65854E-05
P/R 16481 Fn3-7 32 None 0.2486 None 1.0 N 0.71 0.394 0.512651460143 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
P/S 16481 Fn3-7 32 None 0.2396 None 1.0 D 0.763 0.418 0.326074293725 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/N 16582 Fn3-8 32 rs760072934 0.6667 0.328 1.0 N 0.715 0.347 0.272639205421 gnomAD-2.1.1 7.16E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
K/N 16582 Fn3-8 32 rs760072934 0.6667 0.328 1.0 N 0.715 0.347 0.272639205421 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
K/N 16582 Fn3-8 32 rs760072934 0.6667 0.328 1.0 N 0.715 0.347 0.272639205421 gnomAD-4.0.0 3.10049E-06 None None None None N None 6.68163E-05 0 None 0 0 None 0 0 0 0 0
K/T 16582 Fn3-8 32 rs1175062582 0.346 0.127 1.0 N 0.676 0.505 0.326616659874 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
K/T 16582 Fn3-8 32 rs1175062582 0.346 0.127 1.0 N 0.676 0.505 0.326616659874 gnomAD-4.0.0 1.59344E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86175E-06 0 0
P/L 16682 Fn3-9 32 rs1349579168 0.2451 0.006 0.997 D 0.636 0.502 0.717612795731 gnomAD-2.1.1 4.09E-06 None None None None I None 0 0 None 0 5.69E-05 None 0 None 0 0 0
P/L 16682 Fn3-9 32 rs1349579168 0.2451 0.006 0.997 D 0.636 0.502 0.717612795731 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 1.94856E-04 None 0 0 0 0 0
P/L 16682 Fn3-9 32 rs1349579168 0.2451 0.006 0.997 D 0.636 0.502 0.717612795731 gnomAD-4.0.0 1.24064E-06 None None None None I None 0 0 None 0 2.24467E-05 None 0 0 0 1.09856E-05 0
P/S 16682 Fn3-9 32 None 0.2524 None 0.978 D 0.581 0.41 0.298056030225 gnomAD-4.0.0 4.78432E-06 None None None None I None 0 0 None 0 0 None 0 0 8.58797E-06 0 0
P/T 16682 Fn3-9 32 rs1231714517 0.2061 -0.033 0.997 D 0.573 0.427 0.461759001683 gnomAD-2.1.1 4.09E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.11E-06 0
P/T 16682 Fn3-9 32 rs1231714517 0.2061 -0.033 0.997 D 0.573 0.427 0.461759001683 gnomAD-4.0.0 1.59477E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86266E-06 0 0
P/A 16782 Fn3-10 32 rs761148844 0.1355 None 1.0 N 0.678 0.365 0.390531646278 gnomAD-4.0.0 6.1708E-06 None None None None I None 0 0 None 0 0 None 0 0 7.20382E-06 0 1.66036E-05
P/T 16782 Fn3-10 32 rs761148844 0.2204 -0.448 1.0 D 0.744 0.467 0.453679287548 gnomAD-2.1.1 4.09E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.03E-06 0
P/T 16782 Fn3-10 32 rs761148844 0.2204 -0.448 1.0 D 0.744 0.467 0.453679287548 gnomAD-4.0.0 6.85644E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00477E-07 0 0
P/H 16883 Fn3-11 32 rs758756600 0.596 -0.264 1.0 D 0.629 0.453 0.658254632336 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.57E-05 0
P/H 16883 Fn3-11 32 rs758756600 0.596 -0.264 1.0 D 0.629 0.453 0.658254632336 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/H 16883 Fn3-11 32 rs758756600 0.596 -0.264 1.0 D 0.629 0.453 0.658254632336 gnomAD-4.0.0 9.30027E-06 None None None None I None 0 0 None 0 0 None 0 3.29164E-04 1.10232E-05 0 0
P/L 16883 Fn3-11 32 rs758756600 0.4564 None 1.0 D 0.72 0.469 0.801424462809 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 16883 Fn3-11 32 rs758756600 0.4564 None 1.0 D 0.72 0.469 0.801424462809 gnomAD-4.0.0 6.58033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47189E-05 0 0
P/S 16883 Fn3-11 32 rs397517602 0.3247 None 1.0 N 0.765 0.366 0.361958692863 gnomAD-4.0.0 2.40064E-06 None None None None I None 1.26695E-04 0 None 0 0 None 0 0 0 0 0
P/Q 17078 Fn3-12 32 None 0.2447 None 1.0 D 0.689 0.507 0.52633505579 gnomAD-4.0.0 1.59307E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86207E-06 0 0
P/S 17078 Fn3-12 32 None 0.2066 None 1.0 D 0.749 0.467 0.480046427281 gnomAD-4.0.0 1.59308E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43349E-05 0
E/A 17400 Fn3-14 32 rs773027240 0.2853 -0.141 0.999 N 0.613 0.54 0.414539908741 gnomAD-2.1.1 2.86E-05 None None None None I None 4.14E-05 0 None 0 0 None 0 None 0 5.47E-05 0
E/A 17400 Fn3-14 32 rs773027240 0.2853 -0.141 0.999 N 0.613 0.54 0.414539908741 gnomAD-3.1.2 5.26E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 8.83E-05 0 0
E/A 17400 Fn3-14 32 rs773027240 0.2853 -0.141 0.999 N 0.613 0.54 0.414539908741 gnomAD-4.0.0 1.2217E-04 None None None None I None 6.68074E-05 0 None 0 0 None 0 0 1.61116E-04 0 3.20513E-05
P/H 17500 Fn3-15 31 rs1384771900 0.2056 -0.3 1.0 N 0.624 0.498 0.59498951386 gnomAD-2.1.1 8.19E-06 None None None None I None 0 0 None 0 5.73E-05 None 0 None 0 9.07E-06 0
P/S 17500 Fn3-15 31 None 0.1372 None 0.995 N 0.628 0.391 0.311079019809 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 17600 Fn3-16 32 rs745629273 0.1881 0.811 0.822 N 0.621 0.32 0.26547132957 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
E/K 17600 Fn3-16 32 rs745629273 0.1881 0.811 0.822 N 0.621 0.32 0.26547132957 gnomAD-4.0.0 2.05356E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79952E-06 0 1.65777E-05
E/D 17795 Fn3-17 32 rs1447853975 0.0772 None None N 0.149 0.072 0.0611884634855 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/D 17795 Fn3-17 32 rs1447853975 0.0772 None None N 0.149 0.072 0.0611884634855 gnomAD-4.0.0 6.57825E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47154E-05 0 0
E/K 17795 Fn3-17 32 None 0.422 None 0.22 N 0.579 0.246 0.243972157842 gnomAD-4.0.0 6.16065E-06 None None None None I None 0 0 None 0 0 None 0 0 7.19831E-06 0 1.65777E-05
P/A 17893 Fn3-18 32 None 0.0974 None 1.0 N 0.663 0.394 0.39843156188 gnomAD-4.0.0 1.59511E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86617E-06 0 0
P/H 17893 Fn3-18 32 None 0.221 None 1.0 N 0.627 0.502 0.51891315781 gnomAD-4.0.0 6.84928E-07 None None None None I None 0 0 None 0 0 None 0 0 9.0026E-07 0 0
P/R 17893 Fn3-18 32 rs1576340594 0.1835 None 1.0 N 0.678 0.442 0.494700469353 gnomAD-4.0.0 6.84928E-07 None None None None I None 2.99652E-05 0 None 0 0 None 0 0 0 0 0
P/T 17893 Fn3-18 32 None 0.1451 None 1.0 N 0.715 0.449 0.459906663326 gnomAD-4.0.0 1.59511E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.03122E-05
E/K 18096 Fn3-19 32 None 0.4287 None 0.998 N 0.543 0.362 0.365120060079 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/V 18096 Fn3-19 32 None 0.3926 None 1.0 N 0.673 0.527 0.596093875869 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/A 18197 Fn3-20 32 rs1475050139 0.0921 None 0.026 N 0.191 0.194 0.1749357433 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/A 18197 Fn3-20 32 rs1475050139 0.0921 None 0.026 N 0.191 0.194 0.1749357433 gnomAD-4.0.0 6.58189E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47167E-05 0 0
P/S 18197 Fn3-20 32 rs1475050139 0.1526 None 0.811 N 0.442 0.281 0.235664433957 gnomAD-4.0.0 1.59361E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86331E-06 0 0
P/L 18303 Fn3-21 32 None 0.1094 None 0.085 N 0.517 0.439 0.560834375986 gnomAD-4.0.0 3.19368E-06 None None None None I None 0 0 None 0 0 None 0 0 5.73418E-06 0 0
R/S 18510 Fn3-22 32 rs1165541106 0.8077 0.085 0.989 N 0.593 0.311 0.248417906384 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
R/S 18510 Fn3-22 32 rs1165541106 0.8077 0.085 0.989 N 0.593 0.311 0.248417906384 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
R/S 18510 Fn3-22 32 rs1165541106 0.8077 0.085 0.989 N 0.593 0.311 0.248417906384 gnomAD-4.0.0 5.58006E-06 None None None None I None 0 0 None 0 0 None 0 0 7.63134E-06 0 0
P/S 18610 Fn3-23 32 rs1053494929 0.2233 0.079 1.0 N 0.734 0.474 0.352048277211 gnomAD-2.1.1 4.08E-06 None None None None I None 6.5E-05 0 None 0 0 None 0 None 0 0 0
P/S 18610 Fn3-23 32 rs1053494929 0.2233 0.079 1.0 N 0.734 0.474 0.352048277211 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/S 18610 Fn3-23 32 rs1053494929 0.2233 0.079 1.0 N 0.734 0.474 0.352048277211 gnomAD-4.0.0 1.86341E-06 None None None None I None 4.01768E-05 0 None 0 0 None 0 0 0 0 0
K/R 18816 Fn3-24 33 None 0.0918 None 0.928 N 0.545 0.216 0.392239652056 gnomAD-4.0.0 1.60469E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.04433E-05
P/L 18915 Fn3-25 32 rs2052547885 0.1667 None 0.999 N 0.67 0.446 0.623294314964 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 18915 Fn3-25 32 rs2052547885 0.1667 None 0.999 N 0.67 0.446 0.623294314964 gnomAD-4.0.0 6.58007E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47124E-05 0 0
K/T 19019 Fn3-26 32 None 0.2631 None 0.117 N 0.542 0.11 0.19670166235 gnomAD-4.0.0 1.20034E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
P/S 19215 Fn3-27 33 rs776531074 0.144 0.017 0.193 N 0.393 0.245 0.208000267992 gnomAD-2.1.1 4.17E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.21E-06 0
P/S 19215 Fn3-27 33 rs776531074 0.144 0.017 0.193 N 0.393 0.245 0.208000267992 gnomAD-4.0.0 1.60373E-06 None None None None I None 0 0 None 0 0 None 0 0 2.87527E-06 0 0
P/L 20008 Fn3-33 32 rs199839492 0.1304 -0.002 0.801 N 0.542 0.404 0.420447328233 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 1.68653E-04 None 0 None 0 0 0
P/L 20008 Fn3-33 32 rs199839492 0.1304 -0.002 0.801 N 0.542 0.404 0.420447328233 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 1.94401E-04 None 0 0 0 0 0
P/L 20008 Fn3-33 32 rs199839492 0.1304 -0.002 0.801 N 0.542 0.404 0.420447328233 gnomAD-4.0.0 5.57924E-06 None None None None I None 0 0 None 0 2.01414E-04 None 0 0 0 0 0
P/A 20203 Fn3-34 33 None 0.0903 None 0.011 D 0.263 0.269 0.221019684889 gnomAD-4.0.0 6.84432E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99675E-07 0 0
P/L 20203 Fn3-34 33 rs753978233 0.163 -0.111 0.026 N 0.463 0.401 0.468420198123 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/L 20203 Fn3-34 33 rs753978233 0.163 -0.111 0.026 N 0.463 0.401 0.468420198123 gnomAD-4.0.0 1.59246E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8603E-06 0 0
P/S 20203 Fn3-34 33 rs757129250 0.1591 -0.231 0.811 N 0.553 0.307 0.312608672186 gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.13E-05 1.40845E-04
P/S 20203 Fn3-34 33 rs757129250 0.1591 -0.231 0.811 N 0.553 0.307 0.312608672186 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 20203 Fn3-34 33 rs757129250 0.1591 -0.231 0.811 N 0.553 0.307 0.312608672186 gnomAD-4.0.0 6.19974E-06 None None None None I None 0 0 None 0 0 None 0 0 7.63053E-06 0 1.60138E-05
P/L 20302 Fn3-35 32 None 0.1155 None 0.497 N 0.605 0.373 0.56369308836 gnomAD-4.0.0 1.60886E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43658E-05 0
P/H 20402 Fn3-36 32 None 0.5231 None 1.0 N 0.628 0.464 0.432826170204 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/D 20600 Fn3-37 32 rs1337048658 0.1582 0.202 0.999 N 0.469 0.144 0.311691414656 gnomAD-2.1.1 4.02E-06 None None None None I None 0 2.91E-05 None 0 0 None 0 None 0 0 0
E/D 20600 Fn3-37 32 rs1337048658 0.1582 0.202 0.999 N 0.469 0.144 0.311691414656 gnomAD-4.0.0 1.59248E-06 None None None None I None 0 2.28885E-05 None 0 0 None 0 0 0 0 0
P/L 20699 Fn3-38 32 rs1553641061 0.395 None 0.999 N 0.67 0.442 0.675737440431 gnomAD-4.0.0 3.18458E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86681E-05 0
P/Q 20699 Fn3-38 32 None 0.3536 None 1.0 N 0.641 0.441 0.434045841721 gnomAD-4.0.0 1.59229E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4334E-05 0
P/S 20699 Fn3-38 32 rs760330778 0.4094 -0.027 0.998 N 0.619 0.456 0.392547445146 gnomAD-2.1.1 8.07E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 8.94E-06 0
P/S 20699 Fn3-38 32 rs760330778 0.4094 -0.027 0.998 N 0.619 0.456 0.392547445146 gnomAD-4.0.0 3.18446E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86015E-06 1.43336E-05 0
S/T 20994 Fn3-40 32 None 0.0906 None 0.543 N 0.261 0.111 0.134241683229 gnomAD-4.0.0 1.59224E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4334E-05 0
P/L 21095 Fn3-41 32 rs538105258 0.33 -0.193 1.0 N 0.673 0.409 0.634924397808 gnomAD-2.1.1 1.21E-05 None None None None I None 0 5.81E-05 None 0 5.63E-05 None 0 None 0 0 0
P/L 21095 Fn3-41 32 rs538105258 0.33 -0.193 1.0 N 0.673 0.409 0.634924397808 gnomAD-3.1.2 1.97E-05 None None None None I None 0 1.96928E-04 0 0 0 None 0 0 0 0 0
P/L 21095 Fn3-41 32 rs538105258 0.33 -0.193 1.0 N 0.673 0.409 0.634924397808 1000 genomes 1.99681E-04 None None None None I None 0 1.4E-03 None None 0 0 None None None 0 None
P/L 21095 Fn3-41 32 rs538105258 0.33 -0.193 1.0 N 0.673 0.409 0.634924397808 gnomAD-4.0.0 6.20087E-06 None None None None I None 0 6.67379E-05 None 3.38203E-05 2.23954E-05 None 0 0 3.39216E-06 0 0
Q/R 21297 Fn3-42 32 rs372983838 0.1104 None 0.662 N 0.331 0.131 0.183819452728 gnomAD-4.0.0 2.05373E-06 None None None None N None 2.99115E-05 0 None 0 0 None 0 0 0 0 3.31631E-05
N/Y 21591 Fn3-44 33 None 0.2615 None 0.983 N 0.717 0.303 0.422160833541 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/A 21690 Fn3-45 32 None 0.0954 None 0.619 N 0.423 0.299 0.338592109245 gnomAD-4.0.0 6.8442E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99633E-07 0 0
P/L 21690 Fn3-45 32 rs2048495568 0.1907 None 0.998 N 0.665 0.435 0.709645480767 gnomAD-4.0.0 3.18485E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 6.05437E-05
P/S 21690 Fn3-45 32 rs2048495969 0.1542 None 0.995 N 0.613 0.415 0.389904358541 gnomAD-4.0.0 5.47536E-06 None None None None I None 2.99007E-05 0 None 0 0 None 0 0 6.29743E-06 0 0
K/I 21788 Fn3-46 32 None 0.6571 None 0.781 N 0.697 0.318 0.512825096792 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 7.32654E-05
K/N 21788 Fn3-46 32 None 0.7028 None 0.638 N 0.662 0.227 0.186928172975 gnomAD-4.0.0 3.20148E-06 None None None None N None 0 0 None 0 0 None 0 0 5.74363E-06 0 0
K/T 21788 Fn3-46 32 rs1330714909 0.4245 None 0.638 N 0.631 0.22 0.28297238246 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
K/T 21788 Fn3-46 32 rs1330714909 0.4245 None 0.638 N 0.631 0.22 0.28297238246 gnomAD-4.0.0 1.31546E-05 None None None None N None 4.82975E-05 0 None 0 0 None 0 0 0 0 0
E/D 21987 Fn3-47 32 None 0.1113 None 0.117 N 0.237 0.046 0.28798054836 gnomAD-4.0.0 1.59322E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86164E-06 0 0
P/A 22086 Fn3-48 32 None 0.1059 None 0.489 N 0.553 0.226 0.231873229951 gnomAD-4.0.0 6.84592E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99641E-07 0 0
P/R 22187 Fn3-49 32 None 0.2803 None 0.989 N 0.575 0.37 0.458464862945 gnomAD-4.0.0 6.85345E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00336E-07 0 0
P/S 22187 Fn3-49 32 rs1160117316 0.1692 None 0.961 N 0.478 0.36 0.357724736475 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 22187 Fn3-49 32 rs1160117316 0.1692 None 0.961 N 0.478 0.36 0.357724736475 gnomAD-4.0.0 6.57644E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47085E-05 0 0
P/S 22385 Fn3-50 32 rs781562260 0.1939 -0.181 0.988 N 0.604 0.433 0.343560092441 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/S 22385 Fn3-50 32 rs781562260 0.1939 -0.181 0.988 N 0.604 0.433 0.343560092441 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/S 22385 Fn3-50 32 rs781562260 0.1939 -0.181 0.988 N 0.604 0.433 0.343560092441 gnomAD-4.0.0 9.29885E-06 None None None None I None 0 0 None 0 0 None 0 0 1.18696E-05 0 1.60169E-05
R/L 22482 Fn3-51 32 None 0.4046 None 0.967 N 0.509 0.285 0.458464862945 gnomAD-4.0.0 2.05321E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69898E-06 0 0
R/Q 22482 Fn3-51 32 rs200146608 0.1687 0.201 0.992 N 0.399 0.195 None gnomAD-2.1.1 1.61177E-04 None None None None I None 1.65385E-04 2.8311E-04 None 0 2.57865E-04 None 3.27E-05 None 8E-05 1.72872E-04 1.40607E-04
R/Q 22482 Fn3-51 32 rs200146608 0.1687 0.201 0.992 N 0.399 0.195 None gnomAD-3.1.2 1.1843E-04 None None None None I None 1.44851E-04 1.31216E-04 0 0 3.885E-04 None 0 0 1.17696E-04 0 0
R/Q 22482 Fn3-51 32 rs200146608 0.1687 0.201 0.992 N 0.399 0.195 None 1000 genomes 3.99361E-04 None None None None I None 8E-04 0 None None 1E-03 0 None None None 0 None
R/Q 22482 Fn3-51 32 rs200146608 0.1687 0.201 0.992 N 0.399 0.195 None gnomAD-4.0.0 1.05378E-04 None None None None I None 1.33355E-04 2.1679E-04 None 0 2.68204E-04 None 4.68926E-05 0 1.04282E-04 2.19621E-05 1.12093E-04
R/W 22482 Fn3-51 32 rs563233842 0.294 -0.271 1.0 N 0.471 0.392 0.385417323374 gnomAD-2.1.1 4.47743E-04 None None None None I None 0 2.83E-05 None 0 0 None 3.79085E-03 None 0 6.29E-05 0
R/W 22482 Fn3-51 32 rs563233842 0.294 -0.271 1.0 N 0.471 0.392 0.385417323374 gnomAD-3.1.2 1.77732E-04 None None None None I None 0 0 0 0 0 None 0 0 5.88E-05 4.77575E-03 0
R/W 22482 Fn3-51 32 rs563233842 0.294 -0.271 1.0 N 0.471 0.392 0.385417323374 1000 genomes 1.39776E-03 None None None None I None 0 0 None None 0 0 None None None 7.2E-03 None
R/W 22482 Fn3-51 32 rs563233842 0.294 -0.271 1.0 N 0.471 0.392 0.385417323374 gnomAD-4.0.0 2.16965E-04 None None None None I None 1.3344E-05 1.66778E-05 None 0 2.23454E-05 None 0 0 1.35652E-05 3.41548E-03 3.20297E-04
P/L 22774 Fn3-53 32 rs886042240 0.1487 -0.144 1.0 N 0.681 0.514 0.684920834152 gnomAD-2.1.1 4.08E-06 None None None None I None 0 0 None 0 0 None 3.35E-05 None 0 0 0
P/L 22774 Fn3-53 32 rs886042240 0.1487 -0.144 1.0 N 0.681 0.514 0.684920834152 gnomAD-4.0.0 1.59854E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.03693E-05
K/E 22872 Fn3-54 32 None 0.3407 None 0.822 N 0.58 0.258 0.28058544554 gnomAD-4.0.0 1.59481E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43802E-05 0
P/L 23071 Fn3-55 32 rs367664195 0.1177 -0.138 0.822 N 0.531 0.331 None gnomAD-2.1.1 4.03E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/S 23071 Fn3-55 32 None 0.1149 None 0.07 N 0.167 0.138 0.168933306366 gnomAD-4.0.0 1.36879E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79929E-06 0 0
E/D 23170 Fn3-56 32 rs760127657 0.0953 -0.375 0.006 N 0.051 0.01 0.163833314356 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
E/D 23170 Fn3-56 32 rs760127657 0.0953 -0.375 0.006 N 0.051 0.01 0.163833314356 gnomAD-4.0.0 1.09485E-05 None None None None I None 0 0 None 0 0 None 0 0 1.4393E-05 0 0
E/K 23170 Fn3-56 32 rs1334543067 0.2609 0.365 0.963 N 0.429 0.274 0.3085936734 gnomAD-2.1.1 1.43E-05 None None None None I None 0 2.83E-05 None 0 0 None 3.27E-05 None 0 1.57E-05 0
E/K 23170 Fn3-56 32 rs1334543067 0.2609 0.365 0.963 N 0.429 0.274 0.3085936734 gnomAD-3.1.2 1.32E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
E/K 23170 Fn3-56 32 rs1334543067 0.2609 0.365 0.963 N 0.429 0.274 0.3085936734 gnomAD-4.0.0 1.15348E-05 None None None None I None 1.69256E-05 1.69497E-05 None 0 0 None 0 2.24316E-04 7.18205E-06 1.34034E-05 5.69022E-05
E/G 23271 Fn3-57 32 rs779955364 0.1887 -0.363 0.822 N 0.627 0.241 0.343101102393 gnomAD-2.1.1 4.82E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.03E-05 0
E/G 23271 Fn3-57 32 rs779955364 0.1887 -0.363 0.822 N 0.627 0.241 0.343101102393 gnomAD-4.0.0 1.40882E-06 None None None None I None 0 0 None 0 0 None 0 0 1.82615E-06 0 0
R/C 23466 Fn3-58 32 rs749744742 0.3573 -0.049 0.996 N 0.443 0.4 0.34854441366 gnomAD-2.1.1 1.07E-05 None None None None I None 4.13E-05 0 None 0 0 None 0 None 0 1.56E-05 0
R/C 23466 Fn3-58 32 rs749744742 0.3573 -0.049 0.996 N 0.443 0.4 0.34854441366 gnomAD-3.1.2 1.97E-05 None None None None I None 2.42E-05 6.56E-05 0 0 0 None 0 0 1.47E-05 0 0
R/C 23466 Fn3-58 32 rs749744742 0.3573 -0.049 0.996 N 0.443 0.4 0.34854441366 gnomAD-4.0.0 8.67778E-06 None None None None I None 1.33618E-05 1.66756E-05 None 0 0 None 0 0 1.01727E-05 0 0
R/G 23466 Fn3-58 32 None 0.5574 None 0.579 N 0.54 0.278 0.272639205421 gnomAD-4.0.0 6.84309E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99565E-07 0 0
R/H 23466 Fn3-58 32 rs1193026411 0.183 -0.582 0.009 N 0.303 0.122 0.18274738541 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 1.65837E-04
R/H 23466 Fn3-58 32 rs1193026411 0.183 -0.582 0.009 N 0.303 0.122 0.18274738541 gnomAD-4.0.0 1.0949E-05 None None None None I None 0 0 None 0 0 None 0 0 1.07949E-05 2.31895E-05 3.31389E-05
R/P 23466 Fn3-58 32 None 0.467 None 0.004 N 0.291 0.266 0.12205267543 gnomAD-4.0.0 6.84315E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99572E-07 0 0
R/S 23466 Fn3-58 32 rs749744742 0.7487 None 0.579 N 0.497 0.233 0.223146558224 gnomAD-4.0.0 1.36862E-06 None None None None I None 2.98882E-05 0 None 0 0 None 0 1.73551E-04 0 0 0
K/N 23563 Fn3-59 32 rs775933082 0.8288 None 0.549 N 0.371 0.181 0.193865811164 gnomAD-4.0.0 6.84314E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99594E-07 0 0
P/Q 23758 Fn3-60 33 rs374970767 0.4436 -0.123 1.0 N 0.637 0.471 None gnomAD-2.1.1 4.06E-06 None None None None I None 6.49E-05 0 None 0 0 None 0 None 0 0 0
P/Q 23758 Fn3-60 33 rs374970767 0.4436 -0.123 1.0 N 0.637 0.471 None gnomAD-3.1.2 1.32E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/Q 23758 Fn3-60 33 rs374970767 0.4436 -0.123 1.0 N 0.637 0.471 None gnomAD-4.0.0 3.84784E-06 None None None None I None 5.07906E-05 0 None 0 0 None 0 0 0 0 0
P/L 23857 Fn3-61 32 None 0.1022 None 0.454 N 0.445 0.327 0.498065138572 gnomAD-4.0.0 1.59173E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8593E-06 0 0
K/N 23955 Fn3-62 32 None 0.4848 None 0.961 N 0.635 0.146 0.136095386433 gnomAD-4.0.0 6.84658E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00003E-07 0 0
K/Q 23955 Fn3-62 32 None 0.1327 None 0.994 N 0.633 0.255 0.180583059064 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/E 24550 Fn3-66 32 rs1323106581 0.708 None 0.002 N 0.143 0.184 0.223847106136 gnomAD-4.0.0 1.36906E-06 None None None None I None 0 2.23774E-05 None 0 0 None 0 0 0 0 1.65722E-05
R/Q 24647 Fn3-67 32 rs767512581 0.594 0.181 0.992 N 0.598 0.255 0.216624796971 gnomAD-2.1.1 2.42E-05 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 4.48E-05 0
R/Q 24647 Fn3-67 32 rs767512581 0.594 0.181 0.992 N 0.598 0.255 0.216624796971 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
R/Q 24647 Fn3-67 32 rs767512581 0.594 0.181 0.992 N 0.598 0.255 0.216624796971 gnomAD-4.0.0 2.54132E-05 None None None None N None 4.00566E-05 3.33533E-05 None 0 0 None 0 0 2.37363E-05 1.09798E-05 1.12097E-04
S/P 24840 Fn3-68 33 None 0.1151 None 0.007 N 0.172 0.248 0.112648838833 gnomAD-4.0.0 1.59247E-06 None None None None I None 0 0 None 0 0 None 1.88587E-05 0 0 0 0
R/G 24939 Fn3-69 32 rs780582199 0.1295 -0.151 0.024 N 0.501 0.144 0.326074293725 gnomAD-2.1.1 1.07E-05 None None None None I None 0 0 None 0 5.14E-05 None 0 None 8E-05 0 0
R/G 24939 Fn3-69 32 rs780582199 0.1295 -0.151 0.024 N 0.501 0.144 0.326074293725 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 9.43E-05 0 0 0 0
R/G 24939 Fn3-69 32 rs780582199 0.1295 -0.151 0.024 N 0.501 0.144 0.326074293725 gnomAD-4.0.0 3.845E-06 None None None None I None 0 0 None 0 2.42801E-05 None 3.13834E-05 0 0 0 0
K/M 25037 Fn3-70 32 None 0.2749 None 0.999 N 0.624 0.377 0.240491677333 gnomAD-4.0.0 6.84696E-07 None None None None I None 0 0 None 0 0 None 0 0 9.0015E-07 0 0
K/T 25037 Fn3-70 32 None 0.3095 None 0.967 N 0.585 0.344 0.210429274316 gnomAD-4.0.0 1.36939E-06 None None None None I None 0 2.23734E-05 None 0 0 None 0 0 9.0015E-07 0 0
D/E 25236 Fn3-71 33 None 0.1145 None 0.067 N 0.201 0.044 0.0297737177859 gnomAD-4.0.0 6.84467E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99612E-07 0 0
D/N 25236 Fn3-71 33 rs1707754880 0.0828 None 0.988 N 0.666 0.245 0.222439326576 gnomAD-4.0.0 3.18544E-06 None None None None I None 0 0 None 0 0 None 0 0 5.71961E-06 0 0
E/Q 25335 Fn3-72 32 rs1416617749 0.1735 0.31 0.959 N 0.362 0.246 0.240491677333 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.66003E-04
E/Q 25335 Fn3-72 32 rs1416617749 0.1735 0.31 0.959 N 0.362 0.246 0.240491677333 gnomAD-4.0.0 1.59181E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02535E-05
K/T 25632 Fn3-74 32 rs984799615 0.4756 None 0.924 N 0.582 0.397 0.44349138644 gnomAD-3.1.2 1.31E-05 None None None None I None 4.82E-05 0 0 0 0 None 0 0 0 0 0
K/T 25632 Fn3-74 32 rs984799615 0.4756 None 0.924 N 0.582 0.397 0.44349138644 gnomAD-4.0.0 4.05989E-06 None None None None I None 6.98763E-05 0 None 0 0 None 0 0 0 0 0
K/N 25729 Fn3-75 32 rs531490944 0.7937 0.243 0.98 N 0.535 0.244 0.247322355667 gnomAD-2.1.1 2.82E-05 None None None None I None 0 0 None 0 0 None 2.28863E-04 None 0 0 0
K/N 25729 Fn3-75 32 rs531490944 0.7937 0.243 0.98 N 0.535 0.244 0.247322355667 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
K/N 25729 Fn3-75 32 rs531490944 0.7937 0.243 0.98 N 0.535 0.244 0.247322355667 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 0 None None None 1E-03 None
K/N 25729 Fn3-75 32 rs531490944 0.7937 0.243 0.98 N 0.535 0.244 0.247322355667 gnomAD-4.0.0 1.36354E-05 None None None None I None 0 0 None 0 0 None 0 0 0 2.30622E-04 1.60097E-05
Q/R 25922 Fn3-76 33 None 0.221 None 0.684 N 0.514 0.211 0.168933306366 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
P/R 26021 Fn3-77 32 rs727504982 0.1221 0.222 0.001 N 0.13 0.24 0.252162846088 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 0 9.19118E-04
P/R 26021 Fn3-77 32 rs727504982 0.1221 0.222 0.001 N 0.13 0.24 0.252162846088 gnomAD-4.0.0 7.96077E-06 None None None None I None 0 0 None 0 0 None 3.76605E-05 0 8.57898E-06 0 0
P/T 26021 Fn3-77 32 None 0.0799 None 0.166 N 0.409 0.274 0.292062946507 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
M/T 26119 Fn3-78 32 None 0.1783 None 0.007 N 0.347 0.075 0.30212335484 gnomAD-4.0.0 2.73737E-06 None None None None I None 0 0 None 0 0 None 0 0 0 3.47899E-05 1.657E-05
M/V 26119 Fn3-78 32 rs1231026101 0.0667 0.379 None N 0.091 0.07 0.233785782151 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
M/V 26119 Fn3-78 32 rs1231026101 0.0667 0.379 None N 0.091 0.07 0.233785782151 gnomAD-4.0.0 4.79036E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39763E-06 0 1.657E-05
D/N 26318 Fn3-79 33 rs772799438 0.0876 0.665 0.004 N 0.266 0.108 0.158396225186 gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 0 None 6.55E-05 None 0 0 0
D/N 26318 Fn3-79 33 rs772799438 0.0876 0.665 0.004 N 0.266 0.108 0.158396225186 gnomAD-4.0.0 2.05333E-06 None None None None I None 0 0 None 0 0 None 0 0 0 3.47971E-05 0
E/D 26417 Fn3-80 32 rs369019463 0.0971 0.084 0.014 N 0.192 0.034 0.170165803431 gnomAD-2.1.1 2.82E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.24E-05 0
E/D 26417 Fn3-80 32 rs369019463 0.0971 0.084 0.014 N 0.192 0.034 0.170165803431 gnomAD-3.1.2 3.29E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 4.41E-05 0 0
E/D 26417 Fn3-80 32 rs369019463 0.0971 0.084 0.014 N 0.192 0.034 0.170165803431 gnomAD-4.0.0 8.67713E-05 None None None None I None 4.00588E-05 0 None 0 0 None 0 0 1.14439E-04 0 3.20307E-05
E/Q 26417 Fn3-80 32 None 0.2895 None 0.942 N 0.546 0.262 0.238096912614 gnomAD-4.0.0 2.05291E-06 None None None None I None 0 0 None 0 0 None 0 1.7337E-04 8.99549E-07 0 1.657E-05
K/N 26714 Fn3-82 32 None 0.7599 None 0.887 N 0.452 0.13 0.202949470691 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
Q/H 27004 Fn3-84 33 None 0.303 None 0.015 N 0.283 0.178 0.0884992946249 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/R 27103 Fn3-85 32 rs751284217 0.0732 0.123 0.002 N 0.216 0.084 0.252681307341 gnomAD-2.1.1 7.2E-06 None None None None I None 0 0 None 0 5.2E-05 None 0 None 0 7.9E-06 0
K/R 27103 Fn3-85 32 rs751284217 0.0732 0.123 0.002 N 0.216 0.084 0.252681307341 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/R 27103 Fn3-85 32 rs751284217 0.0732 0.123 0.002 N 0.216 0.084 0.252681307341 gnomAD-4.0.0 2.02995E-06 None None None None I None 0 0 None 0 0 None 0 0 2.40985E-06 0 0
K/N 27201 Fn3-86 32 None 0.657 None 0.491 N 0.403 0.162 0.195762928549 gnomAD-4.0.0 1.59297E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86022E-06 0 0
N/D 27401 Fn3-87 33 rs1365991014 0.0857 0.394 None N 0.079 0.112 0.104622674875 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.65837E-04
N/D 27401 Fn3-87 33 rs1365991014 0.0857 0.394 None N 0.079 0.112 0.104622674875 gnomAD-4.0.0 3.18284E-06 None None None None I None 0 2.28676E-05 None 0 0 None 0 0 2.85866E-06 0 0
E/A 27500 Fn3-88 32 None 0.1086 None 0.001 N 0.281 0.246 0.226586394389 gnomAD-4.0.0 1.59122E-06 None None None None I None 0 0 None 0 0 None 0 2.4108E-04 0 0 0
E/K 27500 Fn3-88 32 rs375422359 0.1163 0.742 0.574 N 0.487 0.164 None gnomAD-2.1.1 2.41E-05 None None None None I None 6.46E-05 8.69E-05 None 0 5.57E-05 None 3.27E-05 None 0 0 0
E/K 27500 Fn3-88 32 rs375422359 0.1163 0.742 0.574 N 0.487 0.164 None gnomAD-3.1.2 3.29E-05 None None None None I None 9.66E-05 0 0 0 0 None 0 0 1.47E-05 0 0
E/K 27500 Fn3-88 32 rs375422359 0.1163 0.742 0.574 N 0.487 0.164 None gnomAD-4.0.0 1.1155E-05 None None None None I None 1.06843E-04 5.00233E-05 None 0 2.22946E-05 None 0 0 2.54286E-06 3.29352E-05 0
P/H 27601 Fn3-89 32 rs1268002707 0.1788 -0.142 0.966 N 0.437 0.355 0.396345573744 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.65837E-04
P/H 27601 Fn3-89 32 rs1268002707 0.1788 -0.142 0.966 N 0.437 0.355 0.396345573744 gnomAD-4.0.0 1.59161E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02462E-05
P/S 27601 Fn3-89 32 None 0.0989 None 0.136 N 0.147 0.212 0.20549828249 gnomAD-4.0.0 1.5916E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85865E-06 0 0
P/T 27601 Fn3-89 32 None 0.0792 None 0.801 N 0.346 0.316 0.276065633971 gnomAD-4.0.0 3.18319E-06 None None None None I None 0 0 None 0 2.7784E-05 None 0 0 2.85865E-06 0 0
K/Q 27894 Fn3-91 32 rs753572520 0.3363 0.41 0.983 N 0.664 0.286 0.253726318573 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.66113E-04
K/Q 27894 Fn3-91 32 rs753572520 0.3363 0.41 0.983 N 0.664 0.286 0.253726318573 gnomAD-4.0.0 1.59252E-06 None None None None N None 0 0 None 0 0 None 0 2.41313E-04 0 0 0
R/Q 28185 Fn3-93 32 rs371516793 0.0686 0.111 None N 0.065 0.054 0.0666544352282 gnomAD-2.1.1 2.42E-05 None None None None I None 0 5.82E-05 None 0 1.12347E-04 None 6.56E-05 None 0 0 0
R/Q 28185 Fn3-93 32 rs371516793 0.0686 0.111 None N 0.065 0.054 0.0666544352282 gnomAD-3.1.2 2.63E-05 None None None None I None 2.41E-05 0 0 0 3.86548E-04 None 0 0 1.47E-05 0 0
R/Q 28185 Fn3-93 32 rs371516793 0.0686 0.111 None N 0.065 0.054 0.0666544352282 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
R/Q 28185 Fn3-93 32 rs371516793 0.0686 0.111 None N 0.065 0.054 0.0666544352282 gnomAD-4.0.0 1.85965E-05 None None None None I None 3.99893E-05 5.00434E-05 None 0 2.68204E-04 None 1.56338E-05 0 4.23898E-06 4.39522E-05 3.20215E-05
K/N 28283 Fn3-94 32 None 0.6372 None 0.864 N 0.611 0.221 0.183819452728 gnomAD-4.0.0 1.59124E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85804E-06 0 0
K/R 28283 Fn3-94 32 rs545841306 0.0803 0.225 0.013 N 0.343 0.095 None gnomAD-2.1.1 3.19E-05 None None None None I None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
K/R 28283 Fn3-94 32 rs545841306 0.0803 0.225 0.013 N 0.343 0.095 None gnomAD-3.1.2 4.6E-05 None None None None I None 1.68862E-04 0 0 0 0 None 0 0 0 0 0
K/R 28283 Fn3-94 32 rs545841306 0.0803 0.225 0.013 N 0.343 0.095 None 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
K/R 28283 Fn3-94 32 rs545841306 0.0803 0.225 0.013 N 0.343 0.095 None gnomAD-4.0.0 8.11853E-06 None None None None I None 1.39465E-04 0 None 0 0 None 0 0 0 0 0
D/A 28482 Fn3-95 33 None 0.0688 None None N 0.127 0.113 0.144782658237 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/H 28482 Fn3-95 33 rs762526051 0.1437 -0.374 0.171 N 0.467 0.096 0.141422826196 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
D/N 28482 Fn3-95 33 rs762526051 0.0746 0.194 None N 0.07 0.121 0.107399877778 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
D/N 28482 Fn3-95 33 rs762526051 0.0746 0.194 None N 0.07 0.121 0.107399877778 gnomAD-4.0.0 1.59161E-06 None None None None N None 0 2.28697E-05 None 0 0 None 0 0 0 0 0
E/Q 28581 Fn3-96 32 None 0.147 None 0.117 N 0.413 0.108 0.201204373187 gnomAD-4.0.0 1.59146E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8582E-06 0 0
P/L 28682 Fn3-97 32 rs760467197 0.1171 -0.1 1.0 N 0.715 0.428 0.682346832895 gnomAD-2.1.1 2.42E-05 None None None None I None 0 0 None 0 5.6E-05 None 0 None 0 4.48E-05 0
P/L 28682 Fn3-97 32 rs760467197 0.1171 -0.1 1.0 N 0.715 0.428 0.682346832895 gnomAD-4.0.0 1.71063E-05 None None None None I None 0 0 None 0 1.00903E-04 None 0 0 1.8889E-05 0 0
P/S 28682 Fn3-97 32 rs1158588206 0.1282 -0.217 1.0 N 0.757 0.365 0.380730819819 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.96E-06 0
P/L 28876 Fn3-98 32 rs987601709 0.1182 None None N 0.365 0.227 0.415947407303 gnomAD-4.0.0 6.8424E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99509E-07 0 0
P/S 28876 Fn3-98 32 rs1322696753 0.1646 -0.201 0.062 N 0.412 0.205 0.18274738541 gnomAD-2.1.1 8.04E-06 None None None None I None 0 2.9E-05 None 0 0 None 3.27E-05 None 0 0 0
P/S 28876 Fn3-98 32 rs1322696753 0.1646 -0.201 0.062 N 0.412 0.205 0.18274738541 gnomAD-4.0.0 6.36568E-06 None None None None I None 0 2.28624E-05 None 0 0 None 0 0 0 4.29873E-05 0
R/K 28973 Fn3-99 32 None 0.117 None 0.003 N 0.309 0.128 0.21279746466 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/T 29268 Fn3-101 32 None 0.0676 None 0.062 N 0.264 0.058 0.119812018005 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
K/N 29366 Fn3-102 32 None 0.6477 None 0.324 N 0.495 0.105 0.128392430309 gnomAD-4.0.0 1.3685E-06 None None None None I None 0 0 None 0 0 None 0 0 8.99452E-07 0 1.65662E-05
K/T 29565 Fn3-103 33 rs1263180064 0.1188 0.189 0.183 N 0.423 0.158 0.216624796971 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
K/T 29565 Fn3-103 33 rs1263180064 0.1188 0.189 0.183 N 0.423 0.158 0.216624796971 gnomAD-4.0.0 4.77307E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.29824E-05 0
V/I 30061 Fn3-107 32 rs138958733 0.0707 0.009 None N 0.059 0.049 None gnomAD-2.1.1 4.99E-05 None None None None I None 4.54545E-04 2.83E-05 None 0 0 None 3.27E-05 None 0 7.8E-06 0
V/I 30061 Fn3-107 32 rs138958733 0.0707 0.009 None N 0.059 0.049 None gnomAD-3.1.2 1.11713E-04 None None None None I None 4.10133E-04 0 0 0 0 None 0 0 0 0 0
V/I 30061 Fn3-107 32 rs138958733 0.0707 0.009 None N 0.059 0.049 None 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
V/I 30061 Fn3-107 32 rs138958733 0.0707 0.009 None N 0.059 0.049 None gnomAD-4.0.0 2.66433E-05 None None None None I None 3.3312E-04 1.66639E-05 None 0 0 None 0 0 9.32344E-06 5.48932E-05 1.60036E-05
E/A 30256 Fn3-108 33 None 0.2967 None 0.999 N 0.623 0.533 0.345405024496 gnomAD-4.0.0 6.84213E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99452E-07 0 0
E/K 30256 Fn3-108 33 None 0.3356 None 0.999 N 0.599 0.389 0.296329037015 gnomAD-4.0.0 1.20056E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31268E-06 0 0
K/T 30453 Fn3-110 32 None 0.4464 None 0.997 N 0.622 0.405 0.343101102393 gnomAD-4.0.0 1.59177E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8592E-06 0 0
P/L 30651 Fn3-111 33 None 0.1168 None 0.002 N 0.155 0.324 0.524894780827 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
P/S 30651 Fn3-111 33 rs927540266 0.0992 None 0.01 N 0.12 0.168 0.166414681773 gnomAD-4.0.0 6.16099E-06 None None None None I None 0 0 None 0 0 None 0 1.73671E-04 7.1995E-06 0 0
E/G 30750 Fn3-112 32 None 0.1829 None 0.993 N 0.601 0.408 0.4018988957 gnomAD-4.0.0 6.84205E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99457E-07 0 0
E/V 30750 Fn3-112 32 None 0.2143 None 0.997 N 0.687 0.455 0.488757021912 gnomAD-4.0.0 6.84205E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.15937E-05 0
E/K 30852 Fn3-113 32 rs772252611 0.2702 0.439 0.999 N 0.607 0.396 None gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
E/K 30852 Fn3-113 32 rs772252611 0.2702 0.439 0.999 N 0.607 0.396 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/K 30852 Fn3-113 32 rs772252611 0.2702 0.439 0.999 N 0.607 0.396 None gnomAD-4.0.0 4.33768E-06 None None None None I None 0 0 None 0 0 None 0 0 5.93302E-06 0 0
R/Q 31047 Fn3-114 32 rs753897943 0.199 0.6 1.0 N 0.69 0.341 0.1749357433 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 0 None 9.81E-05 None 0 8.91E-06 0
R/Q 31047 Fn3-114 32 rs753897943 0.199 0.6 1.0 N 0.69 0.341 0.1749357433 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/Q 31047 Fn3-114 32 rs753897943 0.199 0.6 1.0 N 0.69 0.341 0.1749357433 gnomAD-4.0.0 1.11544E-05 None None None None I None 0 0 None 0 0 None 0 0 1.01711E-05 5.48932E-05 1.60113E-05
R/G 31144 Fn3-115 32 rs770088691 0.6436 -0.371 1.0 N 0.585 0.422 0.508934680445 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
R/G 31144 Fn3-115 32 rs770088691 0.6436 -0.371 1.0 N 0.585 0.422 0.508934680445 gnomAD-4.0.0 4.78923E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.95604E-05 1.65645E-05
R/Q 31144 Fn3-115 32 rs561941986 0.2154 0.281 1.0 N 0.675 0.304 0.24896430686 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 9.95E-05 0 None 0 None 4.64E-05 1.78E-05 0
R/Q 31144 Fn3-115 32 rs561941986 0.2154 0.281 1.0 N 0.675 0.304 0.24896430686 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
R/Q 31144 Fn3-115 32 rs561941986 0.2154 0.281 1.0 N 0.675 0.304 0.24896430686 gnomAD-4.0.0 9.91538E-06 None None None None N None 2.67151E-05 0 None 3.37838E-05 0 None 1.56226E-05 0 9.32358E-06 0 1.60102E-05
R/W 31144 Fn3-115 32 rs770088691 0.3594 -0.363 1.0 N 0.722 0.486 0.505335117028 gnomAD-2.1.1 8.04E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 8.89E-06 0
R/W 31144 Fn3-115 32 rs770088691 0.3594 -0.363 1.0 N 0.722 0.486 0.505335117028 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
R/W 31144 Fn3-115 32 rs770088691 0.3594 -0.363 1.0 N 0.722 0.486 0.505335117028 gnomAD-4.0.0 5.57738E-06 None None None None N None 2.67094E-05 0 None 0 0 None 0 0 4.23801E-06 1.09803E-05 1.60102E-05
K/E 31439 Fn3-117 32 None 0.1491 None 0.956 N 0.561 0.29 0.253726318573 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/N 31537 Fn3-118 32 None 0.7288 None 0.999 N 0.708 0.314 0.256283259241 gnomAD-4.0.0 6.85101E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00709E-07 0 0
E/D 31739 Fn3-119 32 None 0.0898 None 0.024 N 0.272 0.025 0.110078149338 gnomAD-4.0.0 6.84219E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99475E-07 0 0
E/G 31838 Fn3-120 32 rs1196738790 0.2378 -0.438 0.83 N 0.657 0.309 0.366277470483 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.65508E-04
E/G 31838 Fn3-120 32 rs1196738790 0.2378 -0.438 0.83 N 0.657 0.309 0.366277470483 gnomAD-4.0.0 2.73693E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69854E-06 0 1.65684E-05
E/V 31838 Fn3-120 32 None 0.2396 None 0.908 N 0.707 0.392 0.363944505237 gnomAD-4.0.0 1.36847E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79902E-06 0 0
D/H 31940 Fn3-121 32 None 0.2937 None 1.0 N 0.625 0.421 0.309839678437 gnomAD-4.0.0 6.84242E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99536E-07 0 0
D/N 31940 Fn3-121 32 rs188213186 0.0986 0.254 0.884 N 0.334 0.282 None gnomAD-2.1.1 8.04E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 8.88E-06 0
D/N 31940 Fn3-121 32 rs188213186 0.0986 0.254 0.884 N 0.334 0.282 None gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
D/N 31940 Fn3-121 32 rs188213186 0.0986 0.254 0.884 N 0.334 0.282 None 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
D/N 31940 Fn3-121 32 rs188213186 0.0986 0.254 0.884 N 0.334 0.282 None gnomAD-4.0.0 2.47871E-06 None None None None I None 2.66574E-05 0 None 0 0 None 0 0 1.69534E-06 0 0
D/V 31940 Fn3-121 32 None 0.1964 None 1.0 N 0.659 0.449 0.466991082792 gnomAD-4.0.0 1.5914E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
P/A 32136 Fn3-122 32 None 0.0811 None 0.98 N 0.551 0.379 0.33085137897 gnomAD-4.0.0 1.37151E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79908E-06 0 0
P/S 32136 Fn3-122 32 rs1553518099 0.1817 None 0.98 N 0.563 0.413 0.373357554552 gnomAD-4.0.0 5.48604E-06 None None None None I None 0 0 None 0 0 None 0 0 6.29679E-06 0 1.65782E-05
R/Q 32233 Fn3-123 32 rs755082341 0.1925 0.157 1.0 N 0.718 0.326 0.256283259241 gnomAD-2.1.1 2.41E-05 None None None None I None 0 2.9E-05 None 9.94E-05 5.57E-05 None 0 None 0 2.67E-05 0
R/Q 32233 Fn3-123 32 rs755082341 0.1925 0.157 1.0 N 0.718 0.326 0.256283259241 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
R/Q 32233 Fn3-123 32 rs755082341 0.1925 0.157 1.0 N 0.718 0.326 0.256283259241 gnomAD-4.0.0 1.42524E-05 None None None None I None 0 1.66667E-05 None 3.37792E-05 2.22926E-05 None 0 0 1.44095E-05 2.19631E-05 1.60056E-05
P/L 32431 Fn3-124 33 rs1060500426 0.1347 -0.29 0.27 N 0.509 0.325 0.44349138644 gnomAD-2.1.1 1.61E-05 None None None None I None 0 1.16144E-04 None 0 0 None 0 None 0 0 0
P/L 32431 Fn3-124 33 rs1060500426 0.1347 -0.29 0.27 N 0.509 0.325 0.44349138644 gnomAD-4.0.0 7.95834E-06 None None None None I None 0 1.14348E-04 None 0 0 None 0 0 0 0 0
P/S 32431 Fn3-124 33 None 0.1365 None 0.27 N 0.413 0.189 0.188950314367 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Q/P 32530 Fn3-125 32 None 0.0776 None 0.002 N 0.125 0.217 0.168933306366 gnomAD-4.0.0 6.84375E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9962E-07 0 0
K/I 32631 Fn3-126 32 rs944963846 0.3712 0.519 0.852 N 0.561 0.258 0.419835214384 gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
K/I 32631 Fn3-126 32 rs944963846 0.3712 0.519 0.852 N 0.561 0.258 0.419835214384 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
K/I 32631 Fn3-126 32 rs944963846 0.3712 0.519 0.852 N 0.561 0.258 0.419835214384 gnomAD-4.0.0 3.84309E-06 None None None None I None 5.07408E-05 0 None 0 0 None 0 0 0 0 0
D/G 32827 Fn3-127 33 rs780460404 0.1912 -0.199 1.0 N 0.665 0.463 0.201204373187 gnomAD-2.1.1 1.21E-05 None None None None N None 0 5.79E-05 None 0 0 None 0 None 0 8.89E-06 0
D/G 32827 Fn3-127 33 rs780460404 0.1912 -0.199 1.0 N 0.665 0.463 0.201204373187 gnomAD-4.0.0 4.77327E-06 None None None None N None 0 4.57268E-05 None 0 0 None 0 0 2.85802E-06 0 0
R/G 32928 Fn3-128 33 rs1490449415 0.6962 -0.255 1.0 N 0.596 0.37 0.424908009808 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
R/G 32928 Fn3-128 33 rs1490449415 0.6962 -0.255 1.0 N 0.596 0.37 0.424908009808 gnomAD-3.1.2 1.31E-05 None None None None N None 0 1.31027E-04 0 0 0 None 0 0 0 0 0
R/G 32928 Fn3-128 33 rs1490449415 0.6962 -0.255 1.0 N 0.596 0.37 0.424908009808 gnomAD-4.0.0 3.8433E-06 None None None None N None 0 5.08526E-05 None 0 0 None 0 0 0 0 0
E/K 33029 Fn3-129 32 rs1431873084 0.2147 0.142 0.645 N 0.526 0.304 0.230578612272 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
E/K 33029 Fn3-129 32 rs1431873084 0.2147 0.142 0.645 N 0.526 0.304 0.230578612272 gnomAD-4.0.0 1.59141E-06 None None None None N None 0 2.28645E-05 None 0 0 None 0 0 0 0 0
W/C 33322 Fn3-130 33 rs775769503 0.6154 0.308 0.958 N 0.495 0.271 0.351830644314 gnomAD-2.1.1 5.64E-05 None None None None I None 0 0 None 0 0 None 2.619E-04 None 0 5.34E-05 0
W/C 33322 Fn3-130 33 rs775769503 0.6154 0.308 0.958 N 0.495 0.271 0.351830644314 gnomAD-3.1.2 2.63E-05 None None None None I None 0 0 0 0 0 None 0 0 5.88E-05 0 0
W/C 33322 Fn3-130 33 rs775769503 0.6154 0.308 0.958 N 0.495 0.271 0.351830644314 gnomAD-4.0.0 6.57194E-06 None None None None I None 2.41301E-05 0 None 0 0 None 0 0 0 0 0
W/G 33322 Fn3-130 33 rs760971514 0.3565 -0.917 0.302 N 0.419 0.265 0.32082282376 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
W/G 33322 Fn3-130 33 rs760971514 0.3565 -0.917 0.302 N 0.419 0.265 0.32082282376 gnomAD-4.0.0 1.36863E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.31959E-05 0
W/R 33322 Fn3-130 33 None 0.6434 None 0.68 N 0.608 0.236 0.364926071151 gnomAD-4.0.0 6.84313E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.1598E-05 0
K/E 33423 Fn3-131 32 rs376528148 0.4041 0.347 0.999 N 0.622 0.462 None gnomAD-2.1.1 5.05E-05 None None None None I None 4.1813E-04 9.15E-05 None 0 0 None 0 None 0 0 0
K/E 33423 Fn3-131 32 rs376528148 0.4041 0.347 0.999 N 0.622 0.462 None gnomAD-3.1.2 1.44545E-04 None None None None I None 4.82439E-04 1.30856E-04 0 0 0 None 0 0 0 0 0
K/E 33423 Fn3-131 32 rs376528148 0.4041 0.347 0.999 N 0.622 0.462 None gnomAD-4.0.0 2.20891E-05 None None None None I None 3.38158E-04 1.04833E-04 None 0 0 None 0 0 0 0 6.54001E-05
K/N 33423 Fn3-131 32 None 0.6581 None 1.0 N 0.719 0.266 0.290962096972 gnomAD-4.0.0 1.66616E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.55855E-05 0
K/R 33720 Fn3-132 32 rs727503535 0.0818 0.229 None N 0.12 0.127 0.295623431141 gnomAD-2.1.1 2.01E-05 None None None None N None 0 1.45028E-04 None 0 0 None 0 None 0 0 0
K/R 33720 Fn3-132 32 rs727503535 0.0818 0.229 None N 0.12 0.127 0.295623431141 gnomAD-4.0.0 9.54678E-06 None None None None N None 0 1.37206E-04 None 0 0 None 0 0 0 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.