Structural position:

  • Domain Type: Fn3
  • Aligned Position: 40
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand C

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
V/I 15694 Fn3-1 38 None 0.0733 None 0.046 N 0.269 0.097 0.406806705197 gnomAD-4.0.0 1.59393E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4332E-05 0
I/T 15795 Fn3-2 38 rs370625853 0.8714 -3.579 0.896 D 0.635 0.451 None gnomAD-2.1.1 8.06E-06 None None None None N None 6.46E-05 2.9E-05 None 0 0 None 0 None 0 0 0
I/T 15795 Fn3-2 38 rs370625853 0.8714 -3.579 0.896 D 0.635 0.451 None gnomAD-3.1.2 1.32E-05 None None None None N None 0 1.31423E-04 0 0 0 None 0 0 0 0 0
I/T 15795 Fn3-2 38 rs370625853 0.8714 -3.579 0.896 D 0.635 0.451 None gnomAD-4.0.0 1.02641E-05 None None None None N None 0 6.79002E-05 None 0 0 None 0 0 7.19055E-06 1.34055E-05 0
I/V 15795 Fn3-2 38 rs750870811 0.1096 -1.937 0.004 N 0.198 0.05 0.466230903105 gnomAD-2.1.1 3.63E-05 None None None None N None 0 0 None 0 0 None 0 None 0 8.02E-05 0
I/V 15795 Fn3-2 38 rs750870811 0.1096 -1.937 0.004 N 0.198 0.05 0.466230903105 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 15795 Fn3-2 38 rs750870811 0.1096 -1.937 0.004 N 0.198 0.05 0.466230903105 gnomAD-4.0.0 9.30212E-06 None None None None N None 0 0 None 0 0 None 0 0 1.27214E-05 0 0
I/L 15896 Fn3-3 38 None 0.2699 None 0.294 N 0.383 0.111 0.608094534769 gnomAD-4.0.0 6.94501E-07 None None None None N None 0 0 None 0 0 None 1.89258E-05 0 0 0 0
I/T 15896 Fn3-3 38 rs1411457226 0.5985 -3.457 0.822 D 0.705 0.459 0.838609721794 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14811E-04 0 None 0 0 None 0 None 0 0 0
I/T 15896 Fn3-3 38 rs1411457226 0.5985 -3.457 0.822 D 0.705 0.459 0.838609721794 gnomAD-3.1.2 6.59E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
I/T 15896 Fn3-3 38 rs1411457226 0.5985 -3.457 0.822 D 0.705 0.459 0.838609721794 gnomAD-4.0.0 3.14099E-06 None None None None N None 1.35523E-05 0 None 0 4.51875E-05 None 0 0 1.7068E-06 0 0
I/V 15896 Fn3-3 38 None 0.0869 None 0.006 N 0.237 0.035 0.321108458156 gnomAD-4.0.0 6.94501E-07 None None None None N None 0 0 None 0 0 None 0 0 9.05897E-07 0 0
V/I 16092 Fn3-4 38 None 0.0693 None 0.001 N 0.215 0.038 0.199424873507 gnomAD-4.0.0 3.18841E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72912E-06 0 0
V/I 16192 Fn3-5 38 rs2057142108 0.0918 None 0.767 N 0.306 0.211 0.590228304998 gnomAD-4.0.0 1.59378E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86341E-06 0 0
V/M 16388 Fn3-6 38 rs1299253449 0.7239 -0.433 0.942 D 0.661 0.472 0.675557862682 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
V/M 16388 Fn3-6 38 rs1299253449 0.7239 -0.433 0.942 D 0.661 0.472 0.675557862682 gnomAD-3.1.2 6.59E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
V/M 16388 Fn3-6 38 rs1299253449 0.7239 -0.433 0.942 D 0.661 0.472 0.675557862682 gnomAD-4.0.0 2.56641E-06 None None None None N None 1.69497E-05 0 None 0 0 None 0 0 0 0 2.85014E-05
I/T 16588 Fn3-8 38 rs1352705790 0.8555 -3.697 0.978 D 0.68 0.566 0.852183005683 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.49E-05 0
I/T 16588 Fn3-8 38 rs1352705790 0.8555 -3.697 0.978 D 0.68 0.566 0.852183005683 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 16588 Fn3-8 38 rs1352705790 0.8555 -3.697 0.978 D 0.68 0.566 0.852183005683 gnomAD-4.0.0 2.48049E-06 None None None None N None 0 0 None 0 0 None 0 0 3.39196E-06 0 0
I/V 16588 Fn3-8 38 rs1251831852 0.1244 None 0.198 N 0.197 0.121 0.392855499163 gnomAD-4.0.0 2.73852E-06 None None None None N None 0 0 None 0 0 None 0 1.73732E-04 2.69946E-06 0 0
V/E 16688 Fn3-9 38 None 0.9966 None 1.0 D 0.869 0.773 0.891958202521 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
I/T 16788 Fn3-10 38 rs397517599 0.9153 -2.96 0.98 D 0.604 0.534 0.749266289315 gnomAD-2.1.1 7.89531E-04 None None None None N None 0 5.74E-05 None 0 0 None 6.91949E-03 None 0 5.51E-05 2.83849E-04
I/T 16788 Fn3-10 38 rs397517599 0.9153 -2.96 0.98 D 0.604 0.534 0.749266289315 gnomAD-3.1.2 1.64487E-04 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 4.96483E-03 0
I/T 16788 Fn3-10 38 rs397517599 0.9153 -2.96 0.98 D 0.604 0.534 0.749266289315 1000 genomes 3.99361E-04 None None None None N None 0 0 None None 0 0 None None None 2E-03 None
I/T 16788 Fn3-10 38 rs397517599 0.9153 -2.96 0.98 D 0.604 0.534 0.749266289315 gnomAD-4.0.0 3.63688E-04 None None None None N None 1.33722E-05 5.03423E-05 None 0 0 None 0 3.31236E-04 4.24103E-06 6.01386E-03 4.81155E-04
I/M 17184 Fn3-13 38 rs767319592 0.5137 -1.645 0.934 N 0.623 0.382 0.525613252392 gnomAD-2.1.1 3.62E-05 None None None None N None 0 0 None 0 0 None 2.94175E-04 None 0 0 0
I/M 17184 Fn3-13 38 rs767319592 0.5137 -1.645 0.934 N 0.623 0.382 0.525613252392 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06954E-04 0
I/M 17184 Fn3-13 38 rs767319592 0.5137 -1.645 0.934 N 0.623 0.382 0.525613252392 gnomAD-4.0.0 8.05965E-06 None None None None N None 0 0 None 0 0 None 0 0 8.47968E-07 1.20799E-04 1.60241E-05
I/T 17184 Fn3-13 38 rs752646731 0.9022 -3.469 0.891 D 0.663 0.489 0.773765334734 gnomAD-2.1.1 5.23E-05 None None None None N None 0 0 None 0 5.57E-05 None 2.94175E-04 None 0 2.67E-05 0
I/T 17184 Fn3-13 38 rs752646731 0.9022 -3.469 0.891 D 0.663 0.489 0.773765334734 gnomAD-3.1.2 1.32E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 17184 Fn3-13 38 rs752646731 0.9022 -3.469 0.891 D 0.663 0.489 0.773765334734 gnomAD-4.0.0 5.51798E-05 None None None None N None 1.33626E-05 0 None 0 4.46349E-05 None 0 0 5.4271E-05 2.19664E-04 3.20482E-05
I/V 17184 Fn3-13 38 rs777442915 0.1111 -1.901 0.267 N 0.291 0.1 0.313210971179 gnomAD-4.0.0 4.77791E-06 None None None None N None 5.67022E-05 0 None 0 0 None 0 0 5.72315E-06 0 0
L/S 17406 Fn3-14 38 rs1370237214 0.9967 None 0.999 N 0.858 0.582 0.816087557028 gnomAD-4.0.0 2.40065E-06 None None None None N None 6.33473E-05 0 None 0 2.75482E-04 None 0 0 0 0 0
L/I 17506 Fn3-15 37 None 0.0849 None 0.005 N 0.242 0.065 0.335164054921 gnomAD-4.0.0 1.36993E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.32385E-05 0
V/I 17606 Fn3-16 38 rs2055325123 0.0954 None 0.117 N 0.337 0.141 0.403328974453 gnomAD-4.0.0 1.59286E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02773E-05
I/F 17801 Fn3-17 38 rs1322346815 0.9405 -2.051 0.782 N 0.645 0.379 0.631150896671 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
I/L 17801 Fn3-17 38 None 0.462 None 0.084 N 0.326 0.055 0.449764926163 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 17801 Fn3-17 38 rs370929667 0.8427 -3.653 0.505 N 0.601 0.468 None gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.67E-05 0
I/T 17801 Fn3-17 38 rs370929667 0.8427 -3.653 0.505 N 0.601 0.468 None gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/T 17801 Fn3-17 38 rs370929667 0.8427 -3.653 0.505 N 0.601 0.468 None gnomAD-4.0.0 1.48804E-05 None None None None N None 0 0 None 3.38135E-05 0 None 0 0 1.86552E-05 0 1.6021E-05
I/V 17801 Fn3-17 38 rs1322346815 0.1097 -2.121 None N 0.211 0.05 0.313210971179 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
I/T 17899 Fn3-18 38 rs369723141 0.8849 None 0.939 D 0.69 0.541 0.850888709144 gnomAD-4.0.0 1.59444E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86508E-06 0 0
I/V 17899 Fn3-18 38 rs1359912614 0.0905 -2.164 0.02 N 0.199 0.092 0.38225645794 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 2.87687E-04 0 0
I/V 17899 Fn3-18 38 rs1359912614 0.0905 -2.164 0.02 N 0.199 0.092 0.38225645794 gnomAD-3.1.2 6.6E-06 None None None None N None 0 0 0 0 0 None 9.44E-05 0 0 0 0
I/V 17899 Fn3-18 38 rs1359912614 0.0905 -2.164 0.02 N 0.199 0.092 0.38225645794 gnomAD-4.0.0 3.85763E-06 None None None None N None 0 0 None 0 0 None 4.72233E-05 0 0 0 0
I/N 18102 Fn3-19 38 rs1318872584 0.9951 None 0.963 D 0.866 0.566 0.877393276936 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/N 18102 Fn3-19 38 rs1318872584 0.9951 None 0.963 D 0.866 0.566 0.877393276936 gnomAD-4.0.0 6.58137E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47193E-05 0 0
I/T 18102 Fn3-19 38 rs1318872584 0.8528 -3.333 0.549 D 0.655 0.451 0.706496497531 gnomAD-2.1.1 1.21E-05 None None None None N None 0 5.81E-05 None 0 5.61E-05 None 0 None 0 0 0
I/T 18102 Fn3-19 38 rs1318872584 0.8528 -3.333 0.549 D 0.655 0.451 0.706496497531 gnomAD-4.0.0 7.97151E-06 None None None None N None 0 4.57896E-05 None 4.77646E-05 0 None 0 0 5.72813E-06 0 0
L/P 18203 Fn3-20 38 rs771560830 0.9954 -1.421 1.0 N 0.933 0.71 0.80784574723 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
L/P 18203 Fn3-20 38 rs771560830 0.9954 -1.421 1.0 N 0.933 0.71 0.80784574723 gnomAD-4.0.0 4.78005E-06 None None None None N None 0 0 None 0 0 None 0 0 8.58846E-06 0 0
L/V 18203 Fn3-20 38 None 0.2499 None 0.999 N 0.589 0.203 0.388495093706 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/L 18309 Fn3-21 38 rs1474621978 0.3568 -0.414 0.247 N 0.511 0.18 0.491317756052 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
V/L 18309 Fn3-21 38 rs1474621978 0.3568 -0.414 0.247 N 0.511 0.18 0.491317756052 gnomAD-4.0.0 6.84905E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00051E-07 0 0
I/T 18516 Fn3-22 38 rs146608896 0.8563 -3.45 0.939 N 0.659 0.505 None gnomAD-2.1.1 7.00686E-04 None None None None N None 7.81702E-03 1.70049E-04 None 0 0 None 0 None 0 0 1.40607E-04
I/T 18516 Fn3-22 38 rs146608896 0.8563 -3.45 0.939 N 0.659 0.505 None gnomAD-3.1.2 2.45446E-03 None None None None N None 8.25967E-03 1.77212E-03 0 0 0 None 0 0 0 0 1.91205E-03
I/T 18516 Fn3-22 38 rs146608896 0.8563 -3.45 0.939 N 0.659 0.505 None 1000 genomes 2.79553E-03 None None None None N None 9.1E-03 1.4E-03 None None 1E-03 0 None None None 0 None
I/T 18516 Fn3-22 38 rs146608896 0.8563 -3.45 0.939 N 0.659 0.505 None gnomAD-4.0.0 4.2468E-04 None None None None N None 7.96425E-03 7.67665E-04 None 0 0 None 0 1.6518E-04 4.23959E-06 0 5.76443E-04
V/A 18616 Fn3-23 38 rs2053304882 0.8544 None 0.78 D 0.559 0.537 0.708570864396 gnomAD-4.0.0 1.5935E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86228E-06 0 0
I/T 18822 Fn3-24 39 rs771542159 0.7939 -3.427 0.001 N 0.624 0.387 0.612226609336 gnomAD-2.1.1 4.07E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.99E-06 0
I/T 18822 Fn3-24 39 rs771542159 0.7939 -3.427 0.001 N 0.624 0.387 0.612226609336 gnomAD-4.0.0 5.48643E-06 None None None None N None 0 0 None 0 0 None 0 0 5.40289E-06 0 3.32049E-05
I/V 18822 Fn3-24 39 None 0.0941 None None N 0.155 0.055 0.356484672536 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/P 18921 Fn3-25 38 rs2052542764 0.9983 None 0.999 N 0.83 0.674 0.798510955838 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/P 18921 Fn3-25 38 rs2052542764 0.9983 None 0.999 N 0.83 0.674 0.798510955838 gnomAD-4.0.0 3.0454E-06 None None None None N None 0 0 None 0 0 None 0 0 3.61505E-06 0 0
V/A 19025 Fn3-26 38 rs762688055 0.5509 -2.808 0.058 N 0.325 0.351 0.600985507913 gnomAD-2.1.1 3.62E-05 None None None None N None 0 0 None 0 5.25818E-04 None 0 None 0 0 0
V/A 19025 Fn3-26 38 rs762688055 0.5509 -2.808 0.058 N 0.325 0.351 0.600985507913 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 5.82298E-04 None 0 0 0 0 0
V/A 19025 Fn3-26 38 rs762688055 0.5509 -2.808 0.058 N 0.325 0.351 0.600985507913 gnomAD-4.0.0 8.6995E-06 None None None None N None 0 0 None 0 2.46615E-04 None 0 0 1.69677E-06 0 1.60421E-05
V/F 19025 Fn3-26 38 None 0.78 None 0.976 D 0.744 0.622 0.750674329801 gnomAD-4.0.0 6.8647E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.6608E-05
V/I 19025 Fn3-26 38 rs181957743 0.0904 -0.612 0.075 N 0.251 0.129 None gnomAD-2.1.1 1.70452E-04 None None None None N None 0 1.08244E-03 None 0 0 None 6.85E-05 None 0 3.93E-05 4.25653E-04
V/I 19025 Fn3-26 38 rs181957743 0.0904 -0.612 0.075 N 0.251 0.129 None gnomAD-3.1.2 1.11873E-04 None None None None N None 2.42E-05 9.18274E-04 0 0 0 None 0 0 2.94E-05 0 0
V/I 19025 Fn3-26 38 rs181957743 0.0904 -0.612 0.075 N 0.251 0.129 None 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
V/I 19025 Fn3-26 38 rs181957743 0.0904 -0.612 0.075 N 0.251 0.129 None gnomAD-4.0.0 5.84285E-05 None None None None N None 1.33987E-05 1.02072E-03 None 0 2.24205E-05 None 0 1.65673E-04 1.9514E-05 5.58809E-05 4.8134E-05
I/L 19221 Fn3-27 39 None 0.2607 None 0.104 N 0.273 0.159 0.392702134506 gnomAD-4.0.0 3.43234E-06 None None None None N None 0 0 None 0 0 None 0 0 4.50574E-06 0 0
I/T 19221 Fn3-27 39 rs907612053 0.8652 None 0.998 D 0.705 0.531 0.764331090147 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 19221 Fn3-27 39 rs907612053 0.8652 None 0.998 D 0.705 0.531 0.764331090147 gnomAD-4.0.0 1.62419E-05 None None None None N None 0 0 None 0 0 None 0 5.16529E-04 1.8075E-05 0 0
I/V 19221 Fn3-27 39 None 0.121 None 0.889 N 0.269 0.136 0.472023113445 gnomAD-4.0.0 6.86467E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.17725E-05 0
L/P 19321 Fn3-28 38 rs1395371412 0.9922 None 1.0 N 0.935 0.696 0.752906115721 gnomAD-4.0.0 1.5922E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86E-06 0 0
I/T 19517 Fn3-29 39 rs72646838 0.715 -3.215 0.201 D 0.669 0.515 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
I/T 19517 Fn3-29 39 rs72646838 0.715 -3.215 0.201 D 0.669 0.515 None gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 0 None 0 9.49367E-03 1.47E-05 0 4.78927E-04
I/T 19517 Fn3-29 39 rs72646838 0.715 -3.215 0.201 D 0.669 0.515 None Taylor (2011) None ARVC het None None N Genetic analysis of TTN in 38 ARVC families, incomplete penetrance None None None None None None None None None None None
I/T 19517 Fn3-29 39 rs72646838 0.715 -3.215 0.201 D 0.669 0.515 None gnomAD-4.0.0 1.6116E-05 None None None None N None 0 1.66817E-05 None 0 0 None 0 9.90753E-04 1.52591E-05 0 1.60113E-05
V/A 19717 Fn3-31 38 None 0.881 None 0.625 D 0.597 0.508 0.734413240494 gnomAD-4.0.0 2.73722E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59831E-06 0 0
V/I 19717 Fn3-31 38 rs1308382519 0.0779 -0.661 0.012 N 0.243 0.146 0.387689773709 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/I 19717 Fn3-31 38 rs1308382519 0.0779 -0.661 0.012 N 0.243 0.146 0.387689773709 gnomAD-4.0.0 3.18353E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86599E-05 0
V/A 19914 Fn3-32 38 None 0.6628 None 0.334 D 0.615 0.51 0.638558423614 gnomAD-4.0.0 1.59322E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8603E-06 0 0
V/I 19914 Fn3-32 38 rs1663045607 0.0759 None 0.002 N 0.277 0.084 0.389283895039 gnomAD-3.1.2 2.63E-05 None None None None N None 9.66E-05 0 0 0 0 None 0 0 0 0 0
V/I 19914 Fn3-32 38 rs1663045607 0.0759 None 0.002 N 0.277 0.084 0.389283895039 gnomAD-4.0.0 4.34038E-06 None None None None N None 6.67842E-05 0 None 0 0 None 0 0 1.69566E-06 0 0
V/A 20209 Fn3-34 39 rs1163844137 0.6841 -2.281 0.998 D 0.617 0.546 0.65752205066 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/A 20209 Fn3-34 39 rs1163844137 0.6841 -2.281 0.998 D 0.617 0.546 0.65752205066 gnomAD-4.0.0 2.73759E-06 None None None None N None 2.99043E-05 0 None 0 0 None 0 0 2.6989E-06 0 0
V/G 20209 Fn3-34 39 rs1163844137 0.913 -3.1 1.0 D 0.874 0.655 0.829325791028 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/G 20209 Fn3-34 39 rs1163844137 0.913 -3.1 1.0 D 0.874 0.655 0.829325791028 gnomAD-4.0.0 1.36879E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79927E-06 0 0
M/T 20308 Fn3-35 38 None 0.4235 None None N 0.417 0.179 0.784996480802 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 20408 Fn3-36 38 rs753847129 0.8882 -2.485 0.999 D 0.615 0.52 0.772467084153 gnomAD-2.1.1 2.01E-05 None None None None N None 0 0 None 0 0 None 1.63538E-04 None 0 0 0
V/A 20408 Fn3-36 38 rs753847129 0.8882 -2.485 0.999 D 0.615 0.52 0.772467084153 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07727E-04 0
V/A 20408 Fn3-36 38 rs753847129 0.8882 -2.485 0.999 D 0.615 0.52 0.772467084153 gnomAD-4.0.0 6.81955E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.20866E-04 0
V/G 20408 Fn3-36 38 None 0.9773 None 1.0 D 0.886 0.655 0.890858236123 gnomAD-4.0.0 6.8446E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99734E-07 0 0
V/M 20408 Fn3-36 38 rs2049977435 0.8168 None 1.0 N 0.731 0.464 0.724580621126 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/M 20408 Fn3-36 38 rs2049977435 0.8168 None 1.0 N 0.731 0.464 0.724580621126 gnomAD-4.0.0 4.06048E-06 None None None None N None 1.74795E-05 0 None 0 0 None 0 0 3.61504E-06 0 0
V/I 20705 Fn3-38 38 rs1318869377 0.0988 None 0.134 N 0.226 0.162 0.452450644169 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 20705 Fn3-38 38 rs1318869377 0.0988 None 0.134 N 0.226 0.162 0.452450644169 gnomAD-4.0.0 2.56411E-06 None None None None N None 1.69233E-05 0 None 0 0 None 0 0 2.39499E-06 0 0
L/I 20901 Fn3-39 38 None 0.0919 None 0.058 N 0.364 0.08 0.187945064343 gnomAD-4.0.0 1.37149E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79947E-06 0 0
L/P 20901 Fn3-39 38 None 0.9945 None 0.99 N 0.855 0.575 0.854063423762 gnomAD-4.0.0 1.59902E-06 None None None None N None 0 0 None 0 2.79298E-05 None 0 0 0 0 0
L/F 21000 Fn3-40 38 rs772733348 0.9184 -1.918 1.0 D 0.729 0.412 0.459552425292 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.65893E-04
L/F 21000 Fn3-40 38 rs772733348 0.9184 -1.918 1.0 D 0.729 0.412 0.459552425292 gnomAD-4.0.0 2.73782E-06 None None None None N None 0 0 None 0 0 None 0 3.47464E-04 8.99679E-07 0 1.657E-05
L/M 21000 Fn3-40 38 None 0.5088 None 1.0 N 0.679 0.344 0.410071178582 gnomAD-4.0.0 1.59246E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86013E-06 0 0
V/E 21101 Fn3-41 38 None 0.9864 None 0.97 D 0.85 0.719 0.882891302514 gnomAD-4.0.0 1.20039E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31257E-06 0 0
V/M 21101 Fn3-41 38 None 0.5986 None 0.489 N 0.383 0.356 0.557637382247 gnomAD-4.0.0 1.59315E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86157E-06 0 0
V/L 21303 Fn3-42 38 rs372812312 0.2043 None 0.015 N 0.325 0.097 0.405979908929 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 21303 Fn3-42 38 rs372812312 0.2043 None 0.015 N 0.325 0.097 0.405979908929 gnomAD-4.0.0 6.58025E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47137E-05 0 0
V/M 21303 Fn3-42 38 rs372812312 0.3626 -1.115 0.843 N 0.434 0.367 None gnomAD-2.1.1 8.89E-05 None None None None N None 1.29333E-04 0 None 4.98604E-04 0 None 2.94214E-04 None 0 5.37E-05 0
V/M 21303 Fn3-42 38 rs372812312 0.3626 -1.115 0.843 N 0.434 0.367 None gnomAD-3.1.2 3.29E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 4.41E-05 2.07297E-04 0
V/M 21303 Fn3-42 38 rs372812312 0.3626 -1.115 0.843 N 0.434 0.367 None gnomAD-4.0.0 7.31613E-05 None None None None N None 5.34588E-05 0 None 4.73133E-04 0 None 3.12647E-05 1.64745E-04 5.25661E-05 3.07469E-04 1.12165E-04
T/I 21403 Fn3-43 38 rs2042996 0.0302 0.672 None N 0.357 0.201 None gnomAD-2.1.1 3.50373E-01 None None None None N None 5.27651E-01 4.25999E-01 None 2.83546E-01 7.07715E-01 None 5.18502E-01 None 2.76192E-01 2.24116E-01 3.05001E-01
T/I 21403 Fn3-43 38 rs2042996 0.0302 0.672 None N 0.357 0.201 None gnomAD-3.1.2 3.56988E-01 None None None None N None 5.27969E-01 3.79627E-01 5.60307E-01 2.87651E-01 7.06123E-01 None 2.85971E-01 2.75316E-01 2.23166E-01 5.20175E-01 3.26462E-01
T/I 21403 Fn3-43 38 rs2042996 0.0302 0.672 None N 0.357 0.201 None 1000 genomes 5.07588E-01 None None None None N None 5.582E-01 4.078E-01 None None 7.212E-01 2.485E-01 None None None 5.562E-01 None
T/I 21403 Fn3-43 38 rs2042996 0.0302 0.672 None N 0.357 0.201 None gnomAD-4.0.0 2.75244E-01 None None None None N None 5.3375E-01 4.13419E-01 None 2.85637E-01 6.9729E-01 None 2.77941E-01 3.05785E-01 2.15615E-01 5.08019E-01 3.02332E-01
V/A 21597 Fn3-44 39 rs1374577570 0.865 -2.742 0.998 D 0.619 0.542 0.783386442946 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/A 21597 Fn3-44 39 rs1374577570 0.865 -2.742 0.998 D 0.619 0.542 0.783386442946 gnomAD-4.0.0 1.59207E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
V/E 21597 Fn3-44 39 None 0.9957 None 1.0 D 0.882 0.715 0.892875781192 gnomAD-4.0.0 1.59207E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85987E-06 0 0
V/L 21597 Fn3-44 39 rs150661999 0.4719 -0.501 0.981 N 0.575 0.294 0.637308043038 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
V/L 21597 Fn3-44 39 rs150661999 0.4719 -0.501 0.981 N 0.575 0.294 0.637308043038 gnomAD-4.0.0 6.8436E-07 None None None None N None 0 0 None 0 2.52169E-05 None 0 0 0 0 0
V/M 21597 Fn3-44 39 rs150661999 0.6505 -0.884 0.999 D 0.757 0.518 None gnomAD-2.1.1 3.40481E-03 None None None None N None 2.06748E-04 7.6392E-04 None 1.06527E-03 1.02912E-04 None 2.16993E-02 None 4E-05 1.73225E-03 2.95027E-03
V/M 21597 Fn3-44 39 rs150661999 0.6505 -0.884 0.999 D 0.757 0.518 None gnomAD-3.1.2 1.76969E-03 None None None None N None 2.41453E-04 1.83655E-03 0 8.64553E-04 1.9425E-04 None 0 0 1.63322E-03 2.33664E-02 1.43403E-03
V/M 21597 Fn3-44 39 rs150661999 0.6505 -0.884 0.999 D 0.757 0.518 None 1000 genomes 5.99042E-03 None None None None N None 0 1.4E-03 None None 0 2E-03 None None None 2.76E-02 None
V/M 21597 Fn3-44 39 rs150661999 0.6505 -0.884 0.999 D 0.757 0.518 None gnomAD-4.0.0 2.18863E-03 None None None None N None 3.20085E-04 9.83792E-04 None 8.44994E-04 1.78603E-04 None 6.2502E-05 4.12814E-03 1.0801E-03 2.11906E-02 2.91443E-03
V/A 21794 Fn3-46 38 rs2154179261 0.8122 None 0.722 D 0.564 0.438 0.693423972026 gnomAD-4.0.0 2.05753E-06 None None None None N None 5.98695E-05 0 None 0 0 None 0 0 0 0 1.66118E-05
V/I 21794 Fn3-46 38 None 0.0913 -0.576 0.044 N 0.228 0.053 None gnomAD-2.1.1 2.19E-05 None None None None N None 8.44E-05 5.75E-05 None 0 5.29E-05 None 0 None 0 8.01E-06 0
V/I 21794 Fn3-46 38 None 0.0913 -0.576 0.044 N 0.228 0.053 None gnomAD-3.1.2 2.63E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 21794 Fn3-46 38 None 0.0913 -0.576 0.044 N 0.228 0.053 None gnomAD-4.0.0 2.67106E-05 None None None None N None 6.68253E-05 3.35661E-05 None 0 0 None 0 0 2.7164E-05 0 6.42281E-05
V/L 21794 Fn3-46 38 rs373848128 0.3822 -0.579 0.319 N 0.311 0.139 0.269558022972 gnomAD-2.1.1 1.46E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.21E-05 0
V/L 21794 Fn3-46 38 rs373848128 0.3822 -0.579 0.319 N 0.311 0.139 0.269558022972 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 21794 Fn3-46 38 rs373848128 0.3822 -0.579 0.319 N 0.311 0.139 0.269558022972 gnomAD-4.0.0 6.85958E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00862E-07 0 0
V/A 21993 Fn3-47 38 rs1483586965 0.9182 None 0.104 D 0.573 0.462 0.656662538205 gnomAD-4.0.0 1.59318E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86136E-06 0 0
L/F 22092 Fn3-48 38 rs192182734 0.9009 -1.647 0.317 N 0.649 0.306 None gnomAD-2.1.1 2.86E-05 None None None None N None 4.14E-05 1.13161E-04 None 0 0 None 0 None 0 1.57E-05 1.40726E-04
L/F 22092 Fn3-48 38 rs192182734 0.9009 -1.647 0.317 N 0.649 0.306 None gnomAD-3.1.2 1.32E-05 None None None None N None 0 6.56E-05 0 0 0 None 0 0 1.47E-05 0 0
L/F 22092 Fn3-48 38 rs192182734 0.9009 -1.647 0.317 N 0.649 0.306 None 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
L/F 22092 Fn3-48 38 rs192182734 0.9009 -1.647 0.317 N 0.649 0.306 None gnomAD-4.0.0 6.81962E-06 None None None None N None 1.33419E-05 1.33382E-04 None 0 0 None 0 0 8.47817E-07 0 1.60113E-05
L/R 22092 Fn3-48 38 rs1553627146 0.9872 None 0.484 D 0.797 0.462 0.657140475542 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 22193 Fn3-49 38 rs775454536 0.8582 -2.709 0.999 D 0.593 0.629 0.735643650146 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
V/A 22193 Fn3-49 38 rs775454536 0.8582 -2.709 0.999 D 0.593 0.629 0.735643650146 gnomAD-4.0.0 4.78373E-06 None None None None N None 0 0 None 0 2.7933E-05 None 0 0 5.72629E-06 0 0
V/I 22193 Fn3-49 38 rs760767895 0.1223 -0.406 0.999 N 0.585 0.261 0.623733534801 gnomAD-2.1.1 8.1E-06 None None None None N None 0 0 None 0 0 None 6.57E-05 None 0 0 0
V/I 22193 Fn3-49 38 rs760767895 0.1223 -0.406 0.999 N 0.585 0.261 0.623733534801 gnomAD-3.1.2 1.97E-05 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 2.07383E-04 4.78469E-04
V/I 22193 Fn3-49 38 rs760767895 0.1223 -0.406 0.999 N 0.585 0.261 0.623733534801 gnomAD-4.0.0 2.10898E-05 None None None None N None 0 1.67084E-05 None 0 0 None 0 0 1.61139E-05 1.09948E-04 6.4119E-05
V/L 22391 Fn3-50 38 rs756952687 0.5019 -0.501 0.618 N 0.571 0.265 0.566084962815 gnomAD-2.1.1 8.05E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 1.65893E-04
V/L 22391 Fn3-50 38 rs756952687 0.5019 -0.501 0.618 N 0.571 0.265 0.566084962815 gnomAD-4.0.0 6.36878E-06 None None None None N None 0 4.57436E-05 None 0 0 None 0 0 2.86031E-06 0 3.02645E-05
V/I 22488 Fn3-51 38 rs1553622498 0.1051 None 0.835 N 0.428 0.14 0.53099781502 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
L/V 22780 Fn3-53 38 rs878857012 0.0675 -1.947 None N 0.249 0.034 None gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
L/V 22780 Fn3-53 38 rs878857012 0.0675 -1.947 None N 0.249 0.034 None gnomAD-4.0.0 6.38943E-06 None None None None N None 0 0 None 0 0 None 0 0 8.58752E-06 0 3.03067E-05
V/A 22878 Fn3-54 38 None 0.8681 None 0.998 D 0.647 0.674 0.72024247472 gnomAD-4.0.0 6.84482E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99683E-07 0 0
V/M 22878 Fn3-54 38 rs764263517 0.7419 -0.765 0.999 N 0.751 0.483 0.625091758369 gnomAD-2.1.1 1.09121E-04 None None None None N None 0 0 None 0 0 None 0 None 4.67E-05 2.32587E-04 0
V/M 22878 Fn3-54 38 rs764263517 0.7419 -0.765 0.999 N 0.751 0.483 0.625091758369 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 1.88324E-04 0 1.47E-05 0 0
V/M 22878 Fn3-54 38 rs764263517 0.7419 -0.765 0.999 N 0.751 0.483 0.625091758369 gnomAD-4.0.0 4.2785E-05 None None None None N None 0 0 None 0 0 None 3.12832E-05 0 5.42647E-05 0 4.80538E-05
L/F 23077 Fn3-55 38 rs529270980 0.7891 -1.827 0.988 N 0.784 0.444 None gnomAD-2.1.1 1.07E-05 None None None None N None 1.24028E-04 0 None 0 0 None 0 None 0 0 0
L/F 23077 Fn3-55 38 rs529270980 0.7891 -1.827 0.988 N 0.784 0.444 None gnomAD-3.1.2 2.63E-05 None None None None N None 9.66E-05 0 0 0 0 None 0 0 0 0 0
L/F 23077 Fn3-55 38 rs529270980 0.7891 -1.827 0.988 N 0.784 0.444 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
L/F 23077 Fn3-55 38 rs529270980 0.7891 -1.827 0.988 N 0.784 0.444 None gnomAD-4.0.0 1.05378E-05 None None None None N None 1.46729E-04 0 None 0 0 None 0 0 5.08672E-06 0 0
L/I 23077 Fn3-55 38 None 0.0975 None 0.067 N 0.368 0.114 0.283371740733 gnomAD-4.0.0 6.84378E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9963E-07 0 0
L/P 23077 Fn3-55 38 rs772742230 0.9957 -2.22 0.998 N 0.893 0.633 0.86346069705 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
L/P 23077 Fn3-55 38 rs772742230 0.9957 -2.22 0.998 N 0.893 0.633 0.86346069705 gnomAD-4.0.0 1.59217E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43308E-05 0
V/A 23176 Fn3-56 38 rs1258714685 0.6815 -2.696 0.334 D 0.625 0.45 0.677256655742 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
V/A 23176 Fn3-56 38 rs1258714685 0.6815 -2.696 0.334 D 0.625 0.45 0.677256655742 gnomAD-4.0.0 6.15864E-06 None None None None N None 2.98918E-05 0 None 0 0 None 0 0 7.19663E-06 0 0
V/E 23176 Fn3-56 38 rs1258714685 0.988 -3.231 0.781 D 0.856 0.67 0.846472525598 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/E 23176 Fn3-56 38 rs1258714685 0.988 -3.231 0.781 D 0.856 0.67 0.846472525598 gnomAD-4.0.0 6.84293E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65684E-05
V/I 23176 Fn3-56 38 rs1413591624 0.0782 None 0.002 N 0.256 0.057 0.159798565429 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 23176 Fn3-56 38 rs1413591624 0.0782 None 0.002 N 0.256 0.057 0.159798565429 gnomAD-4.0.0 3.84456E-06 None None None None N None 0 0 None 0 2.42777E-05 None 0 0 4.78776E-06 0 0
V/M 23277 Fn3-57 38 rs371513781 0.6862 -0.551 1.0 N 0.775 0.423 None gnomAD-2.1.1 7.61E-05 None None None None N None 4.25E-05 0 None 0 5.5E-05 None 5.48477E-04 None 4.26E-05 2.58E-05 0
V/M 23277 Fn3-57 38 rs371513781 0.6862 -0.551 1.0 N 0.775 0.423 None gnomAD-3.1.2 3.29E-05 None None None None N None 2.42E-05 0 0 0 0 None 9.42E-05 0 4.41E-05 0 0
V/M 23277 Fn3-57 38 rs371513781 0.6862 -0.551 1.0 N 0.775 0.423 None gnomAD-4.0.0 4.04569E-05 None None None None N None 1.36545E-05 0 None 0 2.24568E-05 None 1.59826E-05 0 2.14128E-05 4.13096E-04 1.63838E-05
V/I 23472 Fn3-58 38 rs556399127 0.0733 -0.706 0.29 N 0.213 0.153 0.473065174198 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
V/I 23472 Fn3-58 38 rs556399127 0.0733 -0.706 0.29 N 0.213 0.153 0.473065174198 gnomAD-4.0.0 3.18349E-06 None None None None N None 0 0 None 0 2.77809E-05 None 0 0 2.8591E-06 0 0
I/T 23569 Fn3-59 38 rs1395180090 0.672 None 0.822 D 0.62 0.45 0.79435206604 gnomAD-4.0.0 2.73717E-06 None None None None N None 0 0 None 0 0 None 1.87266E-05 0 8.9957E-07 0 3.31356E-05
I/V 23569 Fn3-59 38 rs1283599647 0.0908 -1.936 0.014 N 0.233 0.068 0.283371740733 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
I/V 23569 Fn3-59 38 rs1283599647 0.0908 -1.936 0.014 N 0.233 0.068 0.283371740733 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
I/V 23569 Fn3-59 38 rs1283599647 0.0908 -1.936 0.014 N 0.233 0.068 0.283371740733 gnomAD-4.0.0 1.31451E-05 None None None None N None 4.82439E-05 0 None 0 0 None 0 0 0 0 0
V/M 23764 Fn3-60 39 rs773302092 0.6437 -0.923 0.982 N 0.691 0.357 0.609194942736 gnomAD-2.1.1 4.05E-06 None None None None N None 0 2.91E-05 None 0 0 None 0 None 0 0 0
V/M 23764 Fn3-60 39 rs773302092 0.6437 -0.923 0.982 N 0.691 0.357 0.609194942736 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/I 23863 Fn3-61 38 rs367822322 0.0699 None None N 0.159 0.151 0.154104182512 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 23863 Fn3-61 38 rs367822322 0.0699 None None N 0.159 0.151 0.154104182512 gnomAD-4.0.0 6.57462E-06 None None None None N None 2.41301E-05 0 None 0 0 None 0 0 0 0 0
V/A 23961 Fn3-62 38 rs886042407 0.7985 -2.48 0.977 D 0.652 0.587 0.705890645922 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
V/A 23961 Fn3-62 38 rs886042407 0.7985 -2.48 0.977 D 0.652 0.587 0.705890645922 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
V/A 23961 Fn3-62 38 rs886042407 0.7985 -2.48 0.977 D 0.652 0.587 0.705890645922 gnomAD-4.0.0 2.91428E-05 None None None None N None 0 0 None 0 0 None 0 0 3.90108E-05 0 1.602E-05
V/I 23961 Fn3-62 38 rs397517690 0.0861 -0.307 0.428 N 0.289 0.18 0.445007932271 gnomAD-2.1.1 1.69564E-04 None None None None N None 0 2.9E-05 None 0 5.62E-05 None 1.14476E-03 None 0 4.47E-05 0
V/I 23961 Fn3-62 38 rs397517690 0.0861 -0.307 0.428 N 0.289 0.18 0.445007932271 gnomAD-3.1.2 6.58E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 1.86258E-03 0
V/I 23961 Fn3-62 38 rs397517690 0.0861 -0.307 0.428 N 0.289 0.18 0.445007932271 1000 genomes 5.99042E-04 None None None None N None 0 0 None None 0 0 None None None 3.1E-03 None
V/I 23961 Fn3-62 38 rs397517690 0.0861 -0.307 0.428 N 0.289 0.18 0.445007932271 gnomAD-4.0.0 6.94406E-05 None None None None N None 4E-05 1.66711E-05 None 0 6.71081E-05 None 0 0 1.01766E-05 9.88424E-04 4.80384E-05
V/L 23961 Fn3-62 38 rs397517690 0.5244 -0.31 0.957 D 0.621 0.337 0.567569374525 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.62E-05 None 0 None 0 0 0
V/L 24160 Fn3-63 39 None 0.3206 None 0.009 N 0.352 0.24 0.358540694251 gnomAD-4.0.0 1.88852E-06 None None None None N None 0 0 None 0 0 None 0 0 3.29086E-06 0 0
V/L 24259 Fn3-64 38 None 0.2248 None 0.9 N 0.301 0.234 0.63781096912 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/F 24360 Fn3-65 38 None 0.9085 None 1.0 D 0.832 0.517 0.858522680276 gnomAD-4.0.0 4.79115E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49822E-06 1.15953E-05 1.65739E-05
V/L 24360 Fn3-65 38 None 0.4557 None 0.997 N 0.623 0.428 0.685011114773 gnomAD-4.0.0 6.84451E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99643E-07 0 0
V/F 24556 Fn3-66 38 rs532581749 0.9351 -1.762 0.998 D 0.84 0.562 0.809456748508 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/F 24556 Fn3-66 38 rs532581749 0.9351 -1.762 0.998 D 0.84 0.562 0.809456748508 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07469E-04 0
V/F 24556 Fn3-66 38 rs532581749 0.9351 -1.762 0.998 D 0.84 0.562 0.809456748508 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
V/F 24556 Fn3-66 38 rs532581749 0.9351 -1.762 0.998 D 0.84 0.562 0.809456748508 gnomAD-4.0.0 6.57125E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07641E-04 0
V/L 24556 Fn3-66 38 None 0.577 None 0.511 D 0.589 0.197 0.511907979761 gnomAD-4.0.0 1.36941E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80002E-06 0 0
V/G 24653 Fn3-67 38 None 0.9812 None 1.0 D 0.871 0.688 0.910307487806 gnomAD-4.0.0 1.36872E-06 None None None None N None 0 0 None 3.8279E-05 0 None 0 0 8.99582E-07 0 0
V/M 24653 Fn3-67 38 None 0.7831 None 1.0 D 0.744 0.483 0.78595867793 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 24846 Fn3-68 39 rs545418788 0.8344 -2.575 0.999 D 0.623 0.581 0.749798479323 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 9.99E-05 0 None 0 None 0 1.79E-05 0
V/A 24846 Fn3-68 39 rs545418788 0.8344 -2.575 0.999 D 0.623 0.581 0.749798479323 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/A 24846 Fn3-68 39 rs545418788 0.8344 -2.575 0.999 D 0.623 0.581 0.749798479323 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
V/A 24846 Fn3-68 39 rs545418788 0.8344 -2.575 0.999 D 0.623 0.581 0.749798479323 gnomAD-4.0.0 3.84539E-06 None None None None N None 0 0 None 4.09165E-05 0 None 0 0 4.78838E-06 0 0
V/I 24846 Fn3-68 39 rs770230639 0.1218 -0.325 0.997 N 0.573 0.254 0.66941582999 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/I 24846 Fn3-68 39 rs770230639 0.1218 -0.325 0.997 N 0.573 0.254 0.66941582999 gnomAD-4.0.0 5.47558E-06 None None None None N None 0 2.23714E-05 None 0 0 None 0 0 2.69884E-06 4.63854E-05 0
L/V 24945 Fn3-69 38 None 0.0939 None 0.025 N 0.335 0.028 0.101711395817 gnomAD-4.0.0 2.40066E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 3.66354E-05
V/A 25043 Fn3-70 38 None 0.8079 None 0.999 D 0.607 0.588 0.699529956698 gnomAD-4.0.0 7.96176E-06 None None None None N None 0 0 None 0 0 None 0 0 1.14435E-05 1.43299E-05 0
V/F 25043 Fn3-70 38 rs559907766 0.9458 -1.573 1.0 D 0.809 0.513 0.793268036239 gnomAD-2.1.1 1.00722E-04 None None None None N None 0 0 None 0 0 None 7.19519E-04 None 0 2.67E-05 0
V/F 25043 Fn3-70 38 rs559907766 0.9458 -1.573 1.0 D 0.809 0.513 0.793268036239 gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 0 None 0 0 0 1.03563E-03 0
V/F 25043 Fn3-70 38 rs559907766 0.9458 -1.573 1.0 D 0.809 0.513 0.793268036239 1000 genomes 5.99042E-04 None None None None N None 0 0 None None 0 0 None None None 3.1E-03 None
V/F 25043 Fn3-70 38 rs559907766 0.9458 -1.573 1.0 D 0.809 0.513 0.793268036239 gnomAD-4.0.0 6.32342E-05 None None None None N None 0 0 None 0 0 None 0 0 6.78396E-06 9.88316E-04 6.40451E-05
V/I 25043 Fn3-70 38 None 0.0923 None 0.997 N 0.595 0.237 0.556302983289 gnomAD-4.0.0 4.79148E-06 None None None None N None 0 0 None 0 0 None 0 0 6.29896E-06 0 0
V/L 25043 Fn3-70 38 rs559907766 0.5859 -0.182 0.997 D 0.627 0.299 0.548993143269 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/L 25043 Fn3-70 38 rs559907766 0.5859 -0.182 0.997 D 0.627 0.299 0.548993143269 gnomAD-4.0.0 1.36899E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99852E-07 1.15955E-05 0
L/P 25341 Fn3-72 38 None 0.9874 None 0.999 N 0.872 0.645 0.703937047953 gnomAD-4.0.0 1.59189E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85941E-06 0 0
L/V 25341 Fn3-72 38 rs576067412 0.0786 -2.124 0.198 N 0.309 0.098 0.29527378943 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
L/V 25341 Fn3-72 38 rs576067412 0.0786 -2.124 0.198 N 0.309 0.098 0.29527378943 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
L/V 25341 Fn3-72 38 rs576067412 0.0786 -2.124 0.198 N 0.309 0.098 0.29527378943 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
L/V 25341 Fn3-72 38 rs576067412 0.0786 -2.124 0.198 N 0.309 0.098 0.29527378943 gnomAD-4.0.0 2.56327E-06 None None None None N None 3.38066E-05 0 None 0 0 None 0 0 0 0 0
V/A 25442 Fn3-73 38 rs1707475730 0.5152 None 0.998 D 0.647 0.551 0.768949010136 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/A 25442 Fn3-73 38 rs1707475730 0.5152 None 0.998 D 0.647 0.551 0.768949010136 gnomAD-4.0.0 2.5637E-06 None None None None N None 0 0 None 0 0 None 0 0 2.39406E-06 0 2.84576E-05
V/L 25442 Fn3-73 38 rs1217166434 0.3995 -0.485 0.981 N 0.601 0.31 0.632608894576 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
V/L 25442 Fn3-73 38 rs1217166434 0.3995 -0.485 0.981 N 0.601 0.31 0.632608894576 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 25442 Fn3-73 38 rs1217166434 0.3995 -0.485 0.981 N 0.601 0.31 0.632608894576 gnomAD-4.0.0 6.57886E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47115E-05 0 0
V/A 25638 Fn3-74 38 rs771843047 0.8452 -2.67 0.69 D 0.605 0.503 0.692605645839 gnomAD-2.1.1 4.11E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.04E-06 0
V/A 25638 Fn3-74 38 rs771843047 0.8452 -2.67 0.69 D 0.605 0.503 0.692605645839 gnomAD-4.0.0 1.37563E-06 None None None None N None 0 0 None 0 0 None 0 0 9.02706E-07 0 1.66722E-05
V/I 25638 Fn3-74 38 None 0.0692 None 0.006 N 0.215 0.138 0.40417439687 gnomAD-4.0.0 1.61223E-06 None None None None N None 0 0 None 0 0 None 0 0 2.89343E-06 0 0
V/M 25735 Fn3-75 38 rs369532567 0.7641 -0.875 1.0 D 0.707 0.525 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
V/M 25735 Fn3-75 38 rs369532567 0.7641 -0.875 1.0 D 0.707 0.525 None gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/M 25735 Fn3-75 38 rs369532567 0.7641 -0.875 1.0 D 0.707 0.525 None gnomAD-4.0.0 2.56345E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78822E-06 0 0
V/I 25928 Fn3-76 39 None 0.0757 None 0.067 N 0.303 0.121 0.388653054685 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
L/P 26027 Fn3-77 38 rs773883465 0.9967 -2.26 1.0 D 0.838 0.715 0.842886931792 gnomAD-2.1.1 8.07E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 8.94E-06 0
L/P 26027 Fn3-77 38 rs773883465 0.9967 -2.26 1.0 D 0.838 0.715 0.842886931792 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/P 26027 Fn3-77 38 rs773883465 0.9967 -2.26 1.0 D 0.838 0.715 0.842886931792 gnomAD-4.0.0 1.48767E-05 None None None None N None 1.33565E-05 0 None 0 0 None 0 0 1.78026E-05 0 3.2039E-05
V/I 26125 Fn3-78 38 rs1213696680 0.0898 None 0.004 N 0.297 0.088 0.386721274199 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
V/I 26125 Fn3-78 38 rs1213696680 0.0898 None 0.004 N 0.297 0.088 0.386721274199 gnomAD-4.0.0 1.31492E-05 None None None None N None 4.82486E-05 0 None 0 0 None 0 0 0 0 0
V/I 26324 Fn3-79 39 rs747655927 0.0776 -0.716 0.006 N 0.153 0.073 0.386721274199 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
V/I 26324 Fn3-79 39 rs747655927 0.0776 -0.716 0.006 N 0.153 0.073 0.386721274199 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 26324 Fn3-79 39 rs747655927 0.0776 -0.716 0.006 N 0.153 0.073 0.386721274199 gnomAD-4.0.0 6.57358E-06 None None None None N None 2.41336E-05 0 None 0 0 None 0 0 0 0 0
V/A 26423 Fn3-80 38 rs576203363 0.6677 -2.538 0.892 D 0.599 0.602 0.650396906566 gnomAD-2.1.1 8.07E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
V/A 26423 Fn3-80 38 rs576203363 0.6677 -2.538 0.892 D 0.599 0.602 0.650396906566 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07383E-04 0
V/A 26423 Fn3-80 38 rs576203363 0.6677 -2.538 0.892 D 0.599 0.602 0.650396906566 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
V/A 26423 Fn3-80 38 rs576203363 0.6677 -2.538 0.892 D 0.599 0.602 0.650396906566 gnomAD-4.0.0 4.95833E-06 None None None None N None 0 0 None 0 0 None 0 0 5.08617E-06 2.19611E-05 0
V/G 26423 Fn3-80 38 None 0.9246 None 0.983 D 0.861 0.789 0.851511300201 gnomAD-4.0.0 6.8434E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65706E-05
V/L 26423 Fn3-80 38 rs1706066147 0.2604 None 0.025 N 0.347 0.19 0.288727942641 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.96799E-04 0 0 0 None 0 0 0 0 0
V/L 26423 Fn3-80 38 rs1706066147 0.2604 None 0.025 N 0.347 0.19 0.288727942641 gnomAD-4.0.0 1.97259E-05 None None None None N None 0 1.96799E-04 None 0 0 None 0 0 0 0 0
V/A 26524 Fn3-81 38 None 0.5241 None 0.834 D 0.645 0.49 0.752298016129 gnomAD-4.0.0 1.59276E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
V/L 26524 Fn3-81 38 rs1705941525 0.3064 None 0.263 N 0.621 0.109 0.547426921019 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 26524 Fn3-81 38 rs1705941525 0.3064 None 0.263 N 0.621 0.109 0.547426921019 gnomAD-4.0.0 6.57635E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47098E-05 0 0
I/M 26720 Fn3-82 38 rs376363284 0.4196 -1.474 0.983 N 0.653 0.259 None gnomAD-2.1.1 4.29E-05 None None None None N None 4.13E-05 0 None 3.87372E-04 0 None 0 None 0 4.7E-05 1.40568E-04
I/M 26720 Fn3-82 38 rs376363284 0.4196 -1.474 0.983 N 0.653 0.259 None gnomAD-3.1.2 1.11779E-04 None None None None N None 9.66E-05 0 0 2.88018E-04 0 None 0 0 1.7646E-04 0 0
I/M 26720 Fn3-82 38 rs376363284 0.4196 -1.474 0.983 N 0.653 0.259 None gnomAD-4.0.0 9.11071E-05 None None None None N None 6.67717E-05 0 None 3.71672E-04 0 None 0 0 1.07657E-04 1.09789E-05 4.80415E-05
I/T 26720 Fn3-82 38 rs879183549 0.6564 None 0.892 D 0.659 0.498 None gnomAD-4.0.0 1.59164E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02499E-05
V/A 26817 Fn3-83 38 rs1559343682 0.7105 None 0.987 N 0.6 0.64 0.740987729001 gnomAD-4.0.0 1.59157E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85919E-06 0 0
V/F 26817 Fn3-83 38 rs1367929877 0.8398 None 1.0 D 0.766 0.621 0.82151840403 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/F 26817 Fn3-83 38 rs1367929877 0.8398 None 1.0 D 0.766 0.621 0.82151840403 gnomAD-4.0.0 6.57445E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47046E-05 0 0
V/A 27010 Fn3-84 39 rs369235214 0.8045 -2.572 0.999 D 0.591 0.641 None gnomAD-2.1.1 2.42E-05 None None None None N None 0 0 None 0 0 None 0 None 0 5.34E-05 0
V/A 27010 Fn3-84 39 rs369235214 0.8045 -2.572 0.999 D 0.591 0.641 None gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.88E-05 0 0
V/A 27010 Fn3-84 39 rs369235214 0.8045 -2.572 0.999 D 0.591 0.641 None gnomAD-4.0.0 2.10731E-05 None None None None N None 0 0 None 0 0 None 0 0 2.6279E-05 0 4.80415E-05
V/A 27207 Fn3-86 38 rs755441250 0.9143 -2.53 0.978 D 0.611 0.506 0.709532479457 gnomAD-2.1.1 1.63E-05 None None None None N None 0 0 None 0 2.2792E-04 None 0 None 0 0 0
V/A 27207 Fn3-86 38 rs755441250 0.9143 -2.53 0.978 D 0.611 0.506 0.709532479457 gnomAD-4.0.0 7.97123E-06 None None None None N None 0 0 None 0 1.39369E-04 None 0 0 0 0 0
V/I 27207 Fn3-86 38 rs1348567940 0.0923 -0.255 0.37 N 0.259 0.219 0.391156786388 gnomAD-2.1.1 4.07E-06 None None None None N None 0 0 None 0 0 None 3.29E-05 None 0 0 0
V/I 27207 Fn3-86 38 rs1348567940 0.0923 -0.255 0.37 N 0.259 0.219 0.391156786388 gnomAD-4.0.0 3.42381E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7998E-06 3.48254E-05 0
I/T 27407 Fn3-87 39 rs376037252 0.7154 -3.483 0.997 N 0.712 0.476 None gnomAD-2.1.1 5E-05 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 1.01655E-04 0
I/T 27407 Fn3-87 39 rs376037252 0.7154 -3.483 0.997 N 0.712 0.476 None gnomAD-3.1.2 5.92E-05 None None None None N None 0 0 0 0 0 None 0 0 1.17623E-04 0 4.78011E-04
I/T 27407 Fn3-87 39 rs376037252 0.7154 -3.483 0.997 N 0.712 0.476 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
I/T 27407 Fn3-87 39 rs376037252 0.7154 -3.483 0.997 N 0.712 0.476 None gnomAD-4.0.0 7.5603E-05 None None None None N None 1.33305E-05 0 None 0 0 None 0 0 9.83281E-05 1.09808E-05 6.40205E-05
I/V 27407 Fn3-87 39 rs752734736 0.0865 -2.058 0.798 N 0.267 0.141 0.411401001288 gnomAD-4.0.0 1.59139E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
V/A 27607 Fn3-89 38 rs752494467 0.7034 -2.548 0.334 D 0.613 0.517 0.662910326475 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/A 27607 Fn3-89 38 rs752494467 0.7034 -2.548 0.334 D 0.613 0.517 0.662910326475 gnomAD-4.0.0 2.05281E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69855E-06 0 0
V/A 27803 Fn3-90 38 None 0.8073 None 0.981 D 0.63 0.548 0.719121032051 gnomAD-4.0.0 1.61557E-06 None None None None N None 0 0 None 0 0 None 0 0 2.89288E-06 0 0
V/F 27803 Fn3-90 38 rs752391829 0.8418 -1.7 0.997 D 0.829 0.535 0.765380577275 gnomAD-2.1.1 7.29E-06 None None None None N None 8.32E-05 0 None 0 0 None 0 None 0 0 0
V/F 27803 Fn3-90 38 rs752391829 0.8418 -1.7 0.997 D 0.829 0.535 0.765380577275 gnomAD-4.0.0 1.61503E-06 None None None None N None 5.86992E-05 0 None 0 0 None 0 0 0 0 0
V/L 27803 Fn3-90 38 None 0.4084 None 0.369 N 0.578 0.243 0.484837542351 gnomAD-4.0.0 1.61503E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.47275E-05 0
V/D 28092 Fn3-92 38 None 0.9992 None 0.998 D 0.893 0.609 0.87026763106 gnomAD-4.0.0 6.8428E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65678E-05
V/G 28092 Fn3-92 38 rs761184333 0.971 -3.334 0.994 D 0.897 0.594 0.850823999335 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
V/G 28092 Fn3-92 38 rs761184333 0.971 -3.334 0.994 D 0.897 0.594 0.850823999335 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
V/G 28092 Fn3-92 38 rs761184333 0.971 -3.334 0.994 D 0.897 0.594 0.850823999335 gnomAD-4.0.0 3.09873E-06 None None None None N None 0 0 None 0 0 None 0 0 3.3905E-06 0 1.60123E-05
V/I 28092 Fn3-92 38 None 0.107 None 0.825 N 0.539 0.175 0.468168183122 gnomAD-4.0.0 1.59168E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43291E-05 0
V/L 28092 Fn3-92 38 None 0.5972 None 0.067 N 0.297 0.171 0.342168650903 gnomAD-4.0.0 1.59168E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8585E-06 0 0
L/P 28191 Fn3-93 38 None 0.9963 None 0.999 N 0.895 0.65 0.853648971886 gnomAD-4.0.0 1.59245E-06 None None None None N None 0 0 None 0 2.78056E-05 None 0 0 0 0 0
V/A 28289 Fn3-94 38 rs534008710 0.7205 -2.362 0.104 D 0.597 0.551 0.587148908892 gnomAD-2.1.1 1.21E-05 None None None None N None 6.46E-05 0 None 0 0 None 3.27E-05 None 0 8.88E-06 0
V/A 28289 Fn3-94 38 rs534008710 0.7205 -2.362 0.104 D 0.597 0.551 0.587148908892 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
V/A 28289 Fn3-94 38 rs534008710 0.7205 -2.362 0.104 D 0.597 0.551 0.587148908892 gnomAD-4.0.0 4.78954E-06 None None None None N None 2.98793E-05 2.23614E-05 None 0 0 None 0 0 3.59778E-06 1.15934E-05 0
V/I 28488 Fn3-95 39 rs377264123 0.0907 -0.773 0.428 N 0.317 0.086 None gnomAD-2.1.1 6.8E-05 None None None None N None 2.06868E-04 2.83E-05 None 0 1.5448E-04 None 0 None 0 7.84E-05 0
V/I 28488 Fn3-95 39 rs377264123 0.0907 -0.773 0.428 N 0.317 0.086 None gnomAD-3.1.2 6.57E-05 None None None None N None 1.4476E-04 1.3113E-04 0 0 0 None 0 0 2.94E-05 0 0
V/I 28488 Fn3-95 39 rs377264123 0.0907 -0.773 0.428 N 0.317 0.086 None gnomAD-4.0.0 3.40879E-05 None None None None N None 1.20138E-04 5.003E-05 None 0 6.69493E-05 None 0 0 3.13622E-05 1.09806E-05 3.20256E-05
V/L 28688 Fn3-97 38 None 0.3511 None 0.997 N 0.593 0.352 0.571828761226 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
I/T 28882 Fn3-98 38 rs374491926 0.7381 -3.286 0.722 N 0.607 0.501 None gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
I/T 28882 Fn3-98 38 rs374491926 0.7381 -3.286 0.722 N 0.607 0.501 None gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
I/T 28882 Fn3-98 38 rs374491926 0.7381 -3.286 0.722 N 0.607 0.501 None gnomAD-4.0.0 3.71866E-06 None None None None N None 5.34359E-05 0 None 0 0 None 0 0 8.47669E-07 1.09813E-05 0
I/V 28882 Fn3-98 38 None 0.0677 None 0.001 N 0.207 0.066 0.327952845175 gnomAD-4.0.0 1.36848E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79903E-06 0 0
V/A 28979 Fn3-99 38 rs1702361151 0.6617 None 0.675 D 0.603 0.478 0.75485893091 gnomAD-4.0.0 1.59132E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
V/F 28979 Fn3-99 38 None 0.5795 None 0.972 D 0.767 0.432 0.80342950347 gnomAD-4.0.0 6.84219E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99454E-07 0 0
V/I 28979 Fn3-99 38 rs201687390 0.0626 -0.799 0.014 N 0.247 0.035 None gnomAD-2.1.1 2.00164E-04 None None None None N None 1.23967E-04 1.13199E-04 None 9.67E-05 1.90466E-03 None 9.81E-05 None 0 5.48E-05 1.40687E-04
V/I 28979 Fn3-99 38 rs201687390 0.0626 -0.799 0.014 N 0.247 0.035 None gnomAD-3.1.2 1.31458E-04 None None None None N None 1.20662E-04 1.31096E-04 0 0 1.15652E-03 None 0 0 7.35E-05 4.13736E-04 0
V/I 28979 Fn3-99 38 rs201687390 0.0626 -0.799 0.014 N 0.247 0.035 None gnomAD-4.0.0 1.40054E-04 None None None None N None 1.46839E-04 1.33378E-04 None 3.37838E-05 8.7007E-04 None 0 1.6442E-04 1.16968E-04 1.86637E-04 1.76118E-04
L/I 29175 Fn3-100 39 None 0.0538 None None N 0.201 0.129 0.276898752692 gnomAD-4.0.0 1.36834E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79886E-06 0 0
V/A 29372 Fn3-102 38 None 0.7527 None 0.517 D 0.579 0.487 0.723938039073 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/L 29372 Fn3-102 38 None 0.4667 None 0.075 N 0.319 0.141 0.52540932818 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
V/L 29571 Fn3-103 39 None 0.4419 None 0.476 N 0.582 0.177 0.410071178582 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
V/M 29571 Fn3-103 39 rs1244032310 0.5891 -1.004 0.978 N 0.755 0.422 0.607763699848 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14705E-04 0 None 0 0 None 0 None 0 0 0
V/M 29571 Fn3-103 39 rs1244032310 0.5891 -1.004 0.978 N 0.755 0.422 0.607763699848 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/M 29571 Fn3-103 39 rs1244032310 0.5891 -1.004 0.978 N 0.755 0.422 0.607763699848 gnomAD-4.0.0 6.57289E-06 None None None None N None 2.41359E-05 0 None 0 0 None 0 0 0 0 0
L/P 29670 Fn3-104 38 rs931707459 0.9927 -2.45 1.0 N 0.897 0.726 0.833606934997 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
L/P 29670 Fn3-104 38 rs931707459 0.9927 -2.45 1.0 N 0.897 0.726 0.833606934997 gnomAD-4.0.0 2.05256E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79889E-06 1.15937E-05 0
I/T 29970 Fn3-106 38 None 0.6309 None 0.722 D 0.609 0.436 0.73655689342 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
V/I 30067 Fn3-107 38 rs747129423 0.0901 -0.118 0.004 N 0.215 0.12 0.389126455913 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/I 30067 Fn3-107 38 rs747129423 0.0901 -0.118 0.004 N 0.215 0.12 0.389126455913 gnomAD-4.0.0 1.59104E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02334E-05
I/L 30262 Fn3-108 39 None 0.2105 None 0.437 N 0.313 0.123 0.533035250729 gnomAD-4.0.0 1.59129E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85824E-06 0 0
V/A 30361 Fn3-109 38 rs1237357912 0.612 -2.958 0.996 D 0.593 0.578 0.699720955005 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 1.3925E-04 0 0
V/A 30361 Fn3-109 38 rs1237357912 0.612 -2.958 0.996 D 0.593 0.578 0.699720955005 gnomAD-4.0.0 3.18228E-06 None None None None N None 0 0 None 0 0 None 3.76492E-05 0 0 0 0
I/N 30459 Fn3-110 38 None 0.9932 None 0.998 D 0.869 0.567 0.865305890032 gnomAD-4.0.0 6.8431E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99564E-07 0 0
I/T 30459 Fn3-110 38 rs1336202751 0.8113 -3.229 0.961 D 0.617 0.524 0.720778980054 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.59E-05 None 0 None 0 0 0
I/T 30459 Fn3-110 38 rs1336202751 0.8113 -3.229 0.961 D 0.617 0.524 0.720778980054 gnomAD-4.0.0 3.42155E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69869E-06 1.15942E-05 1.65689E-05
I/M 30657 Fn3-111 39 rs888042945 0.2977 None 0.984 N 0.618 0.412 0.497613835824 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
I/M 30657 Fn3-111 39 rs888042945 0.2977 None 0.984 N 0.618 0.412 0.497613835824 gnomAD-4.0.0 2.73696E-06 None None None None N None 0 8.94574E-05 None 0 0 None 0 0 0 0 0
I/T 30657 Fn3-111 39 rs942083769 0.755 -3.559 0.896 D 0.601 0.492 0.730582074568 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
I/T 30657 Fn3-111 39 rs942083769 0.755 -3.559 0.896 D 0.601 0.492 0.730582074568 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 6.55E-05 0 0 0 None 0 0 0 0 0
I/T 30657 Fn3-111 39 rs942083769 0.755 -3.559 0.896 D 0.601 0.492 0.730582074568 gnomAD-4.0.0 4.33805E-06 None None None None N None 1.33501E-05 1.66717E-05 None 0 0 None 0 0 2.54291E-06 1.09803E-05 1.60123E-05
I/V 30657 Fn3-111 39 rs940922600 0.0845 -2.151 0.004 N 0.185 0.072 0.361160317528 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
I/V 30657 Fn3-111 39 rs940922600 0.0845 -2.151 0.004 N 0.185 0.072 0.361160317528 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 30657 Fn3-111 39 rs940922600 0.0845 -2.151 0.004 N 0.185 0.072 0.361160317528 gnomAD-4.0.0 2.56235E-06 None None None None N None 3.38295E-05 0 None 0 0 None 0 0 0 0 0
I/T 30858 Fn3-113 38 rs1463927651 0.6301 -3.402 0.822 D 0.719 0.487 0.83593546449 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/T 30858 Fn3-113 38 rs1463927651 0.6301 -3.402 0.822 D 0.719 0.487 0.83593546449 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 30858 Fn3-113 38 rs1463927651 0.6301 -3.402 0.822 D 0.719 0.487 0.83593546449 gnomAD-4.0.0 4.33767E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69515E-06 5.48944E-05 0
V/A 31053 Fn3-114 38 None 0.6304 None 0.334 D 0.605 0.534 0.671746105685 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/L 31053 Fn3-114 38 None 0.2608 None 0.002 N 0.333 0.142 0.348764635752 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/P 31150 Fn3-115 38 None 0.9516 None 0.99 N 0.873 0.585 0.790458859785 gnomAD-4.0.0 1.59107E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
V/I 31445 Fn3-117 38 rs564410456 0.0749 -0.666 0.011 N 0.206 0.145 0.39798585902 gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 1.11309E-04 None 0 None 0 0 0
V/I 31445 Fn3-117 38 rs564410456 0.0749 -0.666 0.011 N 0.206 0.145 0.39798585902 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.93125E-04 None 0 0 0 0 0
V/I 31445 Fn3-117 38 rs564410456 0.0749 -0.666 0.011 N 0.206 0.145 0.39798585902 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
V/I 31445 Fn3-117 38 rs564410456 0.0749 -0.666 0.011 N 0.206 0.145 0.39798585902 gnomAD-4.0.0 3.09824E-06 None None None None N None 0 0 None 0 8.91623E-05 None 0 0 8.47621E-07 0 0
V/L 31445 Fn3-117 38 rs564410456 0.3451 -0.669 0.437 N 0.365 0.191 0.416581338634 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
V/L 31445 Fn3-117 38 rs564410456 0.3451 -0.669 0.437 N 0.365 0.191 0.416581338634 gnomAD-4.0.0 6.84202E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99481E-07 0 0
I/M 31543 Fn3-118 38 rs397517759 0.7034 -1.891 0.627 N 0.565 0.299 0.545825192673 gnomAD-2.1.1 7.67E-05 None None None None N None 0 0 None 0 0 None 5.88466E-04 None 0 8.94E-06 0
I/M 31543 Fn3-118 38 rs397517759 0.7034 -1.891 0.627 N 0.565 0.299 0.545825192673 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
I/M 31543 Fn3-118 38 rs397517759 0.7034 -1.891 0.627 N 0.565 0.299 0.545825192673 gnomAD-4.0.0 5.32967E-05 None None None None N None 0 0 None 3.37975E-05 0 None 0 1.65071E-04 1.69548E-05 6.80825E-04 3.20184E-05
I/T 31543 Fn3-118 38 rs749659528 0.8613 -3.616 0.324 D 0.595 0.474 0.719986826817 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/T 31543 Fn3-118 38 rs749659528 0.8613 -3.616 0.324 D 0.595 0.474 0.719986826817 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
I/T 31543 Fn3-118 38 rs749659528 0.8613 -3.616 0.324 D 0.595 0.474 0.719986826817 gnomAD-4.0.0 6.81771E-06 None None None None N None 0 3.33467E-05 None 0 0 None 0 0 5.08638E-06 3.29446E-05 0
I/V 31543 Fn3-118 38 rs771491701 0.0695 -2.142 None N 0.155 0.082 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
I/V 31543 Fn3-118 38 rs771491701 0.0695 -2.142 None N 0.155 0.082 None gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/V 31543 Fn3-118 38 rs771491701 0.0695 -2.142 None N 0.155 0.082 None gnomAD-4.0.0 1.30154E-05 None None None None N None 0 0 None 0 0 None 0 0 1.61072E-05 2.19597E-05 0
V/G 31745 Fn3-119 38 rs886042114 0.9232 None 0.983 D 0.899 0.724 0.896930761969 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/G 31745 Fn3-119 38 rs886042114 0.9232 None 0.983 D 0.899 0.724 0.896930761969 gnomAD-4.0.0 6.57177E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47003E-05 0 0
V/L 31745 Fn3-119 38 None 0.2823 None 0.598 N 0.493 0.208 0.571897645862 gnomAD-4.0.0 6.84225E-07 None None None None N None 0 0 None 0 0 None 1.87294E-05 0 0 0 0
V/M 31745 Fn3-119 38 rs377191543 0.4794 -1.212 0.994 D 0.693 0.507 None gnomAD-2.1.1 3.57E-05 None None None None N None 8.26E-05 2.83E-05 None 0 1.02764E-04 None 3.27E-05 None 4E-05 2.35E-05 0
V/M 31745 Fn3-119 38 rs377191543 0.4794 -1.212 0.994 D 0.693 0.507 None gnomAD-3.1.2 2.63E-05 None None None None N None 7.24E-05 6.54E-05 0 0 0 None 0 0 0 0 0
V/M 31745 Fn3-119 38 rs377191543 0.4794 -1.212 0.994 D 0.693 0.507 None gnomAD-4.0.0 1.79711E-05 None None None None N None 8.00918E-05 1.66683E-05 None 0 4.45891E-05 None 1.56211E-05 0 1.35619E-05 3.2933E-05 0
V/A 31844 Fn3-120 38 rs776197188 0.6996 -2.582 0.999 D 0.597 0.652 0.752541520907 gnomAD-2.1.1 1.07E-05 None None None None N None 4.13E-05 2.83E-05 None 0 0 None 0 None 0 7.8E-06 0
V/A 31844 Fn3-120 38 rs776197188 0.6996 -2.582 0.999 D 0.597 0.652 0.752541520907 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/A 31844 Fn3-120 38 rs776197188 0.6996 -2.582 0.999 D 0.597 0.652 0.752541520907 gnomAD-4.0.0 4.33817E-06 None None None None N None 2.67073E-05 1.667E-05 None 0 0 None 0 0 3.39061E-06 0 0
V/I 31844 Fn3-120 38 None 0.0902 None 0.997 N 0.579 0.298 0.514643173473 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
L/V 31946 Fn3-121 38 rs1405729797 0.0867 None 0.198 N 0.331 0.222 0.385578977469 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/V 31946 Fn3-121 38 rs1405729797 0.0867 None 0.198 N 0.331 0.222 0.385578977469 gnomAD-4.0.0 6.5741E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47011E-05 0 0
V/A 32142 Fn3-122 38 rs1695611620 0.8053 None 0.184 D 0.47 0.554 0.655853083524 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07383E-04 0
V/A 32142 Fn3-122 38 rs1695611620 0.8053 None 0.184 D 0.47 0.554 0.655853083524 gnomAD-4.0.0 1.8609E-06 None None None None N None 0 0 None 0 0 None 0 0 8.47654E-07 1.09818E-05 1.6019E-05
V/I 32142 Fn3-122 38 rs779663332 0.0574 -0.714 0.001 N 0.185 0.068 None gnomAD-2.1.1 8.1E-05 None None None None N None 0 8.71E-05 None 0 0 None 0 None 2.93485E-04 8.03E-05 3.33667E-04
V/I 32142 Fn3-122 38 rs779663332 0.0574 -0.714 0.001 N 0.185 0.068 None gnomAD-3.1.2 5.26E-05 None None None None N None 2.41E-05 0 0 0 0 None 1.88537E-04 0 7.35E-05 0 0
V/I 32142 Fn3-122 38 rs779663332 0.0574 -0.714 0.001 N 0.185 0.068 None gnomAD-4.0.0 9.05727E-05 None None None None N None 4.00523E-05 3.33489E-05 None 0 2.23035E-05 None 3.36247E-04 0 8.81559E-05 1.09818E-05 2.24266E-04
V/L 32142 Fn3-122 38 None 0.2992 None 0.003 N 0.361 0.096 0.272205846399 gnomAD-4.0.0 6.85027E-07 None None None None N None 0 2.23704E-05 None 0 0 None 0 0 0 0 0
L/F 32239 Fn3-123 38 rs889392294 0.6363 -1.815 0.982 N 0.647 0.337 0.708166648873 gnomAD-2.1.1 8.04E-06 None None None None N None 0 5.79E-05 None 0 0 None 0 None 0 0 0
L/F 32239 Fn3-123 38 rs889392294 0.6363 -1.815 0.982 N 0.647 0.337 0.708166648873 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
L/F 32239 Fn3-123 38 rs889392294 0.6363 -1.815 0.982 N 0.647 0.337 0.708166648873 gnomAD-4.0.0 3.84352E-06 None None None None N None 0 3.39098E-05 None 0 0 None 0 0 0 0 2.84398E-05
L/P 32239 Fn3-123 38 None 0.9801 None 0.997 N 0.891 0.604 0.864429176489 gnomAD-4.0.0 4.10511E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39674E-06 0 0
V/I 32437 Fn3-124 39 None 0.1129 None 0.997 N 0.603 0.263 0.66879460378 gnomAD-4.0.0 1.5916E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85871E-06 0 0
V/L 32437 Fn3-124 39 rs2154142556 0.5842 None 0.997 N 0.635 0.394 0.676840377379 gnomAD-4.0.0 1.5916E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85871E-06 0 0
I/T 32637 Fn3-126 38 rs794729547 0.8811 -3.095 0.989 D 0.721 0.558 0.795880955708 gnomAD-2.1.1 7.13E-06 None None None None N None 0 2.83E-05 None 0 0 None 0 None 0 7.8E-06 0
I/T 32637 Fn3-126 38 rs794729547 0.8811 -3.095 0.989 D 0.721 0.558 0.795880955708 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 32637 Fn3-126 38 rs794729547 0.8811 -3.095 0.989 D 0.721 0.558 0.795880955708 gnomAD-4.0.0 4.95755E-06 None None None None N None 0 1.66683E-05 None 0 0 None 0 0 4.23804E-06 0 3.20215E-05
I/V 32637 Fn3-126 38 rs572465445 0.1271 -1.688 0.333 N 0.201 0.096 0.372087925617 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
I/V 32637 Fn3-126 38 rs572465445 0.1271 -1.688 0.333 N 0.201 0.096 0.372087925617 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 32637 Fn3-126 38 rs572465445 0.1271 -1.688 0.333 N 0.201 0.096 0.372087925617 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
I/V 32637 Fn3-126 38 rs572465445 0.1271 -1.688 0.333 N 0.201 0.096 0.372087925617 gnomAD-4.0.0 6.56668E-06 None None None None N None 2.40604E-05 0 None 0 0 None 0 0 0 0 0
L/F 32833 Fn3-127 39 rs1368567004 0.715 -1.764 0.782 N 0.679 0.319 0.657373984822 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 4.64E-05 0 0
L/F 32833 Fn3-127 39 rs1368567004 0.715 -1.764 0.782 N 0.679 0.319 0.657373984822 gnomAD-4.0.0 1.59111E-06 None None None None N None 0 0 None 0 0 None 1.88232E-05 0 0 0 0
L/P 32833 Fn3-127 39 None 0.9855 None 0.957 N 0.876 0.66 0.855347383591 gnomAD-4.0.0 1.59113E-06 None None None None N None 0 0 None 4.76644E-05 0 None 0 0 0 0 0
I/L 32934 Fn3-128 39 rs915727477 0.2654 None 0.689 N 0.338 0.174 0.440604514059 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06868E-04 0
I/L 32934 Fn3-128 39 rs915727477 0.2654 None 0.689 N 0.338 0.174 0.440604514059 gnomAD-4.0.0 6.57315E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.06868E-04 0
I/M 32934 Fn3-128 39 rs1273309840 0.5013 -1.792 0.998 N 0.639 0.335 0.437850553699 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
I/M 32934 Fn3-128 39 rs1273309840 0.5013 -1.792 0.998 N 0.639 0.335 0.437850553699 gnomAD-4.0.0 6.84226E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99501E-07 0 0
I/V 32934 Fn3-128 39 rs915727477 0.0846 None 0.122 N 0.243 0.094 0.428976297845 gnomAD-4.0.0 8.40229E-06 None None None None N None 0 0 None 0 0 None 0 0 7.87501E-06 0 3.66354E-05
V/M 33328 Fn3-130 39 rs372302484 0.762 -0.781 0.942 D 0.665 0.374 None gnomAD-2.1.1 3.94E-05 None None None None N None 4.14147E-04 0 None 0 5.14E-05 None 0 None 0 0 0
V/M 33328 Fn3-130 39 rs372302484 0.762 -0.781 0.942 D 0.665 0.374 None gnomAD-3.1.2 1.05139E-04 None None None None N None 3.85951E-04 0 0 0 0 None 0 0 0 0 0
V/M 33328 Fn3-130 39 rs372302484 0.762 -0.781 0.942 D 0.665 0.374 None gnomAD-4.0.0 2.23136E-05 None None None None N None 4.80538E-04 0 None 0 0 None 0 0 0 0 0
L/P 33429 Fn3-131 38 rs762983936 0.9945 -1.784 1.0 N 0.923 0.695 0.864991553704 gnomAD-2.1.1 4.14E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.11E-06 0
V/A 33726 Fn3-132 38 None 0.9083 None 0.23 D 0.579 0.575 0.680060995016 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.