SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
R/C | 15697 | Fn3-1 | 41 | rs780334981 | 0.59 | -1.669 | 1.0 | D | 0.909 | 0.459 | 0.528959857459 | gnomAD-2.1.1 | 3.58E-05 | None | None | None | None | N | None | 8.28E-05 | 0 | None | 0 | 5.19E-05 | None | 9.81E-05 | None | 0 | 3.14E-05 | 0 |
R/C | 15697 | Fn3-1 | 41 | rs780334981 | 0.59 | -1.669 | 1.0 | D | 0.909 | 0.459 | 0.528959857459 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 4.83E-05 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
R/C | 15697 | Fn3-1 | 41 | rs780334981 | 0.59 | -1.669 | 1.0 | D | 0.909 | 0.459 | 0.528959857459 | gnomAD-4.0.0 | 5.58195E-05 | None | None | None | None | N | None | 4.01059E-05 | 6.68315E-05 | None | 0 | 2.24085E-05 | None | 0 | 0 | 6.44557E-05 | 5.49137E-05 | 1.60303E-05 |
R/G | 15697 | Fn3-1 | 41 | None | 0.9745 | None | 1.0 | D | 0.777 | 0.477 | 0.560529172091 | gnomAD-4.0.0 | 6.84691E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99915E-07 | 0 | 0 |
R/H | 15697 | Fn3-1 | 41 | rs757663389 | 0.6985 | -2.32 | 1.0 | D | 0.764 | 0.581 | 0.460703734027 | gnomAD-2.1.1 | 3.58E-05 | None | None | None | None | N | None | 8.28E-05 | 0 | None | 0 | 2.59363E-04 | None | 0 | None | 0 | 2.35E-05 | 0 |
R/H | 15697 | Fn3-1 | 41 | rs757663389 | 0.6985 | -2.32 | 1.0 | D | 0.764 | 0.581 | 0.460703734027 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 1.95084E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/H | 15697 | Fn3-1 | 41 | rs757663389 | 0.6985 | -2.32 | 1.0 | D | 0.764 | 0.581 | 0.460703734027 | gnomAD-4.0.0 | 2.17067E-05 | None | None | None | None | N | None | 6.68253E-05 | 0 | None | 0 | 3.58343E-04 | None | 0 | 0 | 1.01774E-05 | 2.19616E-05 | 0 |
C/R | 15899 | Fn3-3 | 41 | rs1232133882 | 0.1223 | -1.364 | None | N | 0.441 | 0.133 | 0.404453528171 | gnomAD-2.1.1 | 9.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.24704E-04 | None | 0 | None | 0 | 0 | 0 |
C/R | 15899 | Fn3-3 | 41 | rs1232133882 | 0.1223 | -1.364 | None | N | 0.441 | 0.133 | 0.404453528171 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
C/R | 15899 | Fn3-3 | 41 | rs1232133882 | 0.1223 | -1.364 | None | N | 0.441 | 0.133 | 0.404453528171 | gnomAD-4.0.0 | 3.1449E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.78273E-05 | None | 0 | 0 | 1.70807E-06 | 0 | 0 |
R/Q | 16095 | Fn3-4 | 41 | rs369453963 | 0.47 | -1.039 | 0.999 | N | 0.511 | 0.324 | None | gnomAD-2.1.1 | 2.87E-05 | None | None | None | None | N | None | 8.29E-05 | 0 | None | 0 | 0 | None | 0 | None | 1.9984E-04 | 7.86E-06 | 0 |
R/Q | 16095 | Fn3-4 | 41 | rs369453963 | 0.47 | -1.039 | 0.999 | N | 0.511 | 0.324 | None | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 1.88644E-04 | 0 | 1.47E-05 | 0 | 0 |
R/Q | 16095 | Fn3-4 | 41 | rs369453963 | 0.47 | -1.039 | 0.999 | N | 0.511 | 0.324 | None | gnomAD-4.0.0 | 8.68408E-06 | None | None | None | None | N | None | 2.67465E-05 | 0 | None | 0 | 0 | None | 7.81348E-05 | 0 | 5.93796E-06 | 0 | 0 |
C/R | 16195 | Fn3-5 | 41 | None | 0.5639 | None | 0.968 | N | 0.791 | 0.478 | 0.726404257552 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
C/Y | 16195 | Fn3-5 | 41 | None | 0.5358 | None | 0.995 | D | 0.732 | 0.277 | 0.679388506755 | gnomAD-4.0.0 | 1.36944E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79998E-06 | 0 | 0 |
R/Q | 16391 | Fn3-6 | 41 | rs200944827 | 0.1768 | -1.214 | 0.271 | D | 0.478 | 0.191 | None | gnomAD-2.1.1 | 1.29208E-04 | None | None | None | None | N | None | 4.14E-05 | 2.55638E-04 | None | 0 | 4.17493E-04 | None | 0 | None | 0 | 1.2584E-04 | 2.82008E-04 |
R/Q | 16391 | Fn3-6 | 41 | rs200944827 | 0.1768 | -1.214 | 0.271 | D | 0.478 | 0.191 | None | gnomAD-3.1.2 | 1.31737E-04 | None | None | None | None | N | None | 9.67E-05 | 4.60163E-04 | 0 | 0 | 3.90625E-04 | None | 0 | 0 | 1.03093E-04 | 0 | 0 |
R/Q | 16391 | Fn3-6 | 41 | rs200944827 | 0.1768 | -1.214 | 0.271 | D | 0.478 | 0.191 | None | gnomAD-4.0.0 | 1.60631E-04 | None | None | None | None | N | None | 5.34845E-05 | 2.8411E-04 | None | 0 | 1.79582E-04 | None | 0 | 0 | 1.84861E-04 | 4.39338E-05 | 1.28254E-04 |
L/R | 16591 | Fn3-8 | 41 | None | 0.1619 | None | 0.999 | N | 0.87 | 0.312 | 0.719045985532 | gnomAD-4.0.0 | 1.59354E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78956E-05 | None | 0 | 0 | 0 | 0 | 0 |
C/F | 16892 | Fn3-11 | 41 | rs958402858 | 0.7824 | None | 1.0 | N | 0.875 | 0.415 | 0.785167026474 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
C/F | 16892 | Fn3-11 | 41 | rs958402858 | 0.7824 | None | 1.0 | N | 0.875 | 0.415 | 0.785167026474 | gnomAD-4.0.0 | 6.57895E-06 | None | None | None | None | N | None | 2.41336E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
C/R | 16892 | Fn3-11 | 41 | rs1256128085 | 0.7465 | -1.498 | 1.0 | N | 0.886 | 0.537 | 0.77036421607 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
C/R | 16892 | Fn3-11 | 41 | rs1256128085 | 0.7465 | -1.498 | 1.0 | N | 0.886 | 0.537 | 0.77036421607 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
C/R | 16892 | Fn3-11 | 41 | rs1256128085 | 0.7465 | -1.498 | 1.0 | N | 0.886 | 0.537 | 0.77036421607 | gnomAD-4.0.0 | 2.16996E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9678E-05 | 0 | 0 |
R/G | 17087 | Fn3-12 | 41 | rs1483164102 | 0.9907 | -2.558 | 1.0 | N | 0.767 | 0.537 | 0.506912157699 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 6.46E-05 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/G | 17087 | Fn3-12 | 41 | rs1483164102 | 0.9907 | -2.558 | 1.0 | N | 0.767 | 0.537 | 0.506912157699 | gnomAD-4.0.0 | 2.73803E-06 | None | None | None | None | N | None | 8.97827E-05 | 2.23674E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/T | 17087 | Fn3-12 | 41 | None | 0.9958 | None | 1.0 | N | 0.75 | 0.481 | 0.451504584351 | gnomAD-4.0.0 | 1.59284E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86172E-06 | 0 | 0 |
I/M | 17187 | Fn3-13 | 41 | None | 0.0884 | None | 0.009 | N | 0.175 | 0.025 | 0.315609569513 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
I/T | 17187 | Fn3-13 | 41 | None | 0.2604 | None | 0.183 | N | 0.529 | 0.17 | 0.54848712621 | gnomAD-4.0.0 | 1.36893E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99794E-07 | 1.15972E-05 | 0 |
K/E | 17409 | Fn3-14 | 41 | rs1203045644 | 0.5822 | -1.986 | 0.999 | N | 0.534 | 0.462 | 0.392855499163 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
K/E | 17409 | Fn3-14 | 41 | rs1203045644 | 0.5822 | -1.986 | 0.999 | N | 0.534 | 0.462 | 0.392855499163 | gnomAD-4.0.0 | 3.18747E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72377E-06 | 0 | 0 |
R/C | 17509 | Fn3-15 | 40 | rs748170111 | 0.7876 | -1.641 | 1.0 | N | 0.891 | 0.481 | 0.365892764245 | gnomAD-2.1.1 | 8.14E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 9E-06 | 0 |
R/C | 17509 | Fn3-15 | 40 | rs748170111 | 0.7876 | -1.641 | 1.0 | N | 0.891 | 0.481 | 0.365892764245 | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 2.07211E-04 | 0 |
R/C | 17509 | Fn3-15 | 40 | rs748170111 | 0.7876 | -1.641 | 1.0 | N | 0.891 | 0.481 | 0.365892764245 | gnomAD-4.0.0 | 4.96392E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.24093E-06 | 3.30033E-05 | 0 |
R/H | 17509 | Fn3-15 | 40 | rs886055267 | 0.6654 | -2.543 | 1.0 | N | 0.771 | 0.484 | 0.423119698836 | gnomAD-2.1.1 | 3.24E-05 | None | None | None | None | N | None | 4.16E-05 | 0 | None | 0 | 1.04679E-04 | None | 3.29E-05 | None | 0 | 3.95E-05 | 0 |
R/H | 17509 | Fn3-15 | 40 | rs886055267 | 0.6654 | -2.543 | 1.0 | N | 0.771 | 0.484 | 0.423119698836 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/H | 17509 | Fn3-15 | 40 | rs886055267 | 0.6654 | -2.543 | 1.0 | N | 0.771 | 0.484 | 0.423119698836 | gnomAD-4.0.0 | 3.16389E-05 | None | None | None | None | N | None | 1.33647E-05 | 1.67096E-05 | None | 0 | 2.24527E-05 | None | 0 | 0 | 3.90133E-05 | 1.09987E-05 | 1.6039E-05 |
Q/E | 17609 | Fn3-16 | 41 | rs777990934 | 0.2635 | -2.417 | 0.625 | N | 0.517 | 0.17 | 0.159798565429 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
Q/E | 17609 | Fn3-16 | 41 | rs777990934 | 0.2635 | -2.417 | 0.625 | N | 0.517 | 0.17 | 0.159798565429 | gnomAD-4.0.0 | 3.18572E-06 | None | None | None | None | N | None | 0 | 4.57561E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
Q/K | 17609 | Fn3-16 | 41 | None | 0.2105 | None | 0.625 | N | 0.582 | 0.216 | 0.115124310173 | gnomAD-4.0.0 | 1.59286E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8613E-06 | 0 | 0 |
Q/L | 17609 | Fn3-16 | 41 | rs368820294 | 0.3039 | -1.206 | 0.891 | N | 0.625 | 0.232 | None | gnomAD-2.1.1 | 1.00062E-04 | None | None | None | None | N | None | 8.27E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.95502E-04 | 0 |
Q/L | 17609 | Fn3-16 | 41 | rs368820294 | 0.3039 | -1.206 | 0.891 | N | 0.625 | 0.232 | None | gnomAD-3.1.2 | 1.77681E-04 | None | None | None | None | N | None | 4.83E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 3.38634E-04 | 0 | 4.77555E-04 |
Q/L | 17609 | Fn3-16 | 41 | rs368820294 | 0.3039 | -1.206 | 0.891 | N | 0.625 | 0.232 | None | gnomAD-4.0.0 | 2.15749E-04 | None | None | None | None | N | None | 2.66773E-05 | 5.00384E-05 | None | 0 | 0 | None | 0 | 0 | 2.89155E-04 | 0 | 3.20328E-05 |
R/Q | 17902 | Fn3-18 | 41 | rs781600329 | 0.2152 | -1.024 | 0.873 | N | 0.481 | 0.311 | 0.177238962908 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 9.97E-05 | 0 | None | 1.63473E-04 | None | 0 | 1.78E-05 | 0 |
R/Q | 17902 | Fn3-18 | 41 | rs781600329 | 0.2152 | -1.024 | 0.873 | N | 0.481 | 0.311 | 0.177238962908 | gnomAD-4.0.0 | 8.21778E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.83406E-05 | 0 | None | 0 | 0 | 5.40107E-06 | 5.80437E-05 | 0 |
R/W | 17902 | Fn3-18 | 41 | rs748647255 | 0.6503 | -0.739 | 0.998 | N | 0.629 | 0.412 | 0.340992353424 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.16E-05 | None | 0 | None | 0 | 1.57E-05 | 0 |
R/W | 17902 | Fn3-18 | 41 | rs748647255 | 0.6503 | -0.739 | 0.998 | N | 0.629 | 0.412 | 0.340992353424 | gnomAD-3.1.2 | 6.6E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/W | 17902 | Fn3-18 | 41 | rs748647255 | 0.6503 | -0.739 | 0.998 | N | 0.629 | 0.412 | 0.340992353424 | gnomAD-4.0.0 | 3.72431E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.47928E-05 | None | 0 | 0 | 3.3945E-06 | 0 | 0 |
R/C | 18105 | Fn3-19 | 41 | rs765739434 | 0.3452 | -1.81 | 1.0 | N | 0.802 | 0.415 | None | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
R/C | 18105 | Fn3-19 | 41 | rs765739434 | 0.3452 | -1.81 | 1.0 | N | 0.802 | 0.415 | None | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 18105 | Fn3-19 | 41 | rs765739434 | 0.3452 | -1.81 | 1.0 | N | 0.802 | 0.415 | None | gnomAD-4.0.0 | 2.0472E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.3751E-05 | 4.39986E-05 | 1.60298E-05 |
R/G | 18105 | Fn3-19 | 41 | None | 0.8682 | None | 0.996 | N | 0.741 | 0.418 | 0.580927594641 | gnomAD-4.0.0 | 6.84844E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00105E-07 | 0 | 0 |
R/H | 18105 | Fn3-19 | 41 | rs760383112 | 0.3318 | -2.794 | 1.0 | N | 0.679 | 0.41 | 0.279370189704 | gnomAD-2.1.1 | 3.94E-05 | None | None | None | None | N | None | 0 | 1.70232E-04 | None | 0 | 0 | None | 9.83E-05 | None | 0 | 1.56E-05 | 0 |
R/H | 18105 | Fn3-19 | 41 | rs760383112 | 0.3318 | -2.794 | 1.0 | N | 0.679 | 0.41 | 0.279370189704 | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 2.42E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/H | 18105 | Fn3-19 | 41 | rs760383112 | 0.3318 | -2.794 | 1.0 | N | 0.679 | 0.41 | 0.279370189704 | gnomAD-4.0.0 | 1.67479E-05 | None | None | None | None | N | None | 1.33693E-05 | 1.50306E-04 | None | 0 | 0 | None | 1.56367E-05 | 0 | 8.48211E-06 | 3.29939E-05 | 4.80893E-05 |
R/T | 18206 | Fn3-20 | 41 | None | 0.8367 | None | 0.003 | N | 0.309 | 0.371 | 0.312001716656 | gnomAD-4.0.0 | 1.59315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02792E-05 |
Q/R | 18312 | Fn3-21 | 41 | rs754977491 | 0.2417 | -1.107 | 0.997 | N | 0.502 | 0.415 | 0.231231049324 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
Q/R | 18312 | Fn3-21 | 41 | rs754977491 | 0.2417 | -1.107 | 0.997 | N | 0.502 | 0.415 | 0.231231049324 | gnomAD-4.0.0 | 1.59458E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86325E-06 | 0 | 0 |
R/K | 18519 | Fn3-22 | 41 | None | 0.0918 | None | None | N | 0.148 | 0.168 | 0.107399877778 | gnomAD-4.0.0 | 1.36906E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79955E-06 | 0 | 0 |
R/T | 18519 | Fn3-22 | 41 | None | 0.8739 | None | 0.117 | N | 0.454 | 0.13 | 0.200317383148 | gnomAD-4.0.0 | 6.84529E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99776E-07 | 0 | 0 |
L/P | 18619 | Fn3-23 | 41 | rs1375513422 | 0.9831 | None | 1.0 | N | 0.851 | 0.628 | 0.830745573214 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
L/P | 18619 | Fn3-23 | 41 | rs1375513422 | 0.9831 | None | 1.0 | N | 0.851 | 0.628 | 0.830745573214 | gnomAD-4.0.0 | 6.58077E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47119E-05 | 0 | 0 |
R/K | 18825 | Fn3-24 | 42 | None | 0.2346 | None | 0.008 | N | 0.183 | 0.143 | 0.226586394389 | gnomAD-4.0.0 | 6.85839E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00513E-07 | 0 | 0 |
R/T | 18825 | Fn3-24 | 42 | None | 0.9008 | None | 0.722 | N | 0.584 | 0.387 | 0.337868961071 | gnomAD-4.0.0 | 2.05752E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.53229E-05 | None | 0 | 0 | 1.80103E-06 | 0 | 0 |
K/T | 19028 | Fn3-26 | 41 | rs765612779 | 0.4191 | -1.94 | 0.999 | N | 0.73 | 0.476 | 0.359763055319 | gnomAD-2.1.1 | 8.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
K/T | 19028 | Fn3-26 | 41 | rs765612779 | 0.4191 | -1.94 | 0.999 | N | 0.73 | 0.476 | 0.359763055319 | gnomAD-4.0.0 | 3.20645E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.73414E-06 | 0 | 0 |
R/C | 19224 | Fn3-27 | 42 | rs746014932 | 0.6981 | -1.892 | 1.0 | N | 0.907 | 0.462 | 0.604474940213 | gnomAD-2.1.1 | 4.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.23E-06 | 0 |
R/C | 19224 | Fn3-27 | 42 | rs746014932 | 0.6981 | -1.892 | 1.0 | N | 0.907 | 0.462 | 0.604474940213 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.42E-05 | 1.31148E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 19224 | Fn3-27 | 42 | rs746014932 | 0.6981 | -1.892 | 1.0 | N | 0.907 | 0.462 | 0.604474940213 | gnomAD-4.0.0 | 1.30575E-05 | None | None | None | None | N | None | 4.01027E-05 | 5.05034E-05 | None | 0 | 0 | None | 0 | 0 | 1.10408E-05 | 0 | 3.21048E-05 |
R/H | 19224 | Fn3-27 | 42 | rs779279322 | 0.6669 | -2.944 | 1.0 | N | 0.726 | 0.539 | None | gnomAD-2.1.1 | 2.21E-05 | None | None | None | None | N | None | 8.52E-05 | 0 | None | 0 | 1.06758E-04 | None | 3.45E-05 | None | 0 | 8.07E-06 | 0 |
R/H | 19224 | Fn3-27 | 42 | rs779279322 | 0.6669 | -2.944 | 1.0 | N | 0.726 | 0.539 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 9.66E-05 | 0 | 0 | 0 | 3.885E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/H | 19224 | Fn3-27 | 42 | rs779279322 | 0.6669 | -2.944 | 1.0 | N | 0.726 | 0.539 | None | gnomAD-4.0.0 | 2.79795E-05 | None | None | None | None | N | None | 5.34616E-05 | 5.04999E-05 | None | 0 | 9.00171E-05 | None | 0 | 0 | 2.71771E-05 | 1.11431E-05 | 1.60524E-05 |
R/L | 19224 | Fn3-27 | 42 | None | 0.9092 | None | 1.0 | N | 0.743 | 0.479 | 0.647476214077 | gnomAD-4.0.0 | 6.86645E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01315E-07 | 0 | 0 |
R/Q | 19324 | Fn3-28 | 41 | rs186809500 | 0.6033 | -1.171 | 1.0 | N | 0.689 | 0.515 | None | gnomAD-2.1.1 | 7.24E-05 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 8.37895E-04 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/Q | 19324 | Fn3-28 | 41 | rs186809500 | 0.6033 | -1.171 | 1.0 | N | 0.689 | 0.515 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 9.73141E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 19324 | Fn3-28 | 41 | rs186809500 | 0.6033 | -1.171 | 1.0 | N | 0.689 | 0.515 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 3E-03 | 0 | None | None | None | 0 | None |
R/Q | 19324 | Fn3-28 | 41 | rs186809500 | 0.6033 | -1.171 | 1.0 | N | 0.689 | 0.515 | None | gnomAD-4.0.0 | 2.35542E-05 | None | None | None | None | N | None | 5.33433E-05 | 3.33556E-05 | None | 0 | 4.24486E-04 | None | 0 | 0 | 4.23901E-06 | 1.09844E-05 | 1.12054E-04 |
R/W | 19324 | Fn3-28 | 41 | rs1203435642 | 0.9211 | -0.844 | 1.0 | N | 0.887 | 0.601 | 0.695533483703 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/W | 19324 | Fn3-28 | 41 | rs1203435642 | 0.9211 | -0.844 | 1.0 | N | 0.887 | 0.601 | 0.695533483703 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/W | 19324 | Fn3-28 | 41 | rs1203435642 | 0.9211 | -0.844 | 1.0 | N | 0.887 | 0.601 | 0.695533483703 | gnomAD-4.0.0 | 6.81886E-06 | None | None | None | None | N | None | 0 | 1.66828E-05 | None | 0 | 2.23374E-05 | None | 0 | 0 | 5.93459E-06 | 1.09861E-05 | 1.60128E-05 |
R/K | 19618 | Fn3-30 | 40 | None | 0.1399 | None | None | N | 0.143 | 0.125 | 0.243398259712 | gnomAD-4.0.0 | 1.36874E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79923E-06 | 0 | 0 |
R/T | 19618 | Fn3-30 | 40 | None | 0.9424 | None | 0.324 | N | 0.513 | 0.338 | 0.314716216878 | gnomAD-4.0.0 | 1.36874E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79923E-06 | 0 | 0 |
R/T | 19917 | Fn3-32 | 41 | None | 0.6818 | None | 0.117 | D | 0.467 | 0.162 | 0.215869574891 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
R/P | 20311 | Fn3-35 | 41 | rs373062007 | 0.9971 | None | 1.0 | N | 0.877 | 0.551 | 0.593086074022 | gnomAD-4.0.0 | 1.37439E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80692E-06 | 0 | 0 |
R/Q | 20311 | Fn3-35 | 41 | rs373062007 | 0.2682 | -0.976 | 1.0 | N | 0.681 | 0.485 | 0.235664433957 | gnomAD-2.1.1 | 8.97E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 9.28984E-04 | None | 1.98216E-04 | None | 0 | 7.85E-06 | 0 |
R/Q | 20311 | Fn3-35 | 41 | rs373062007 | 0.2682 | -0.976 | 1.0 | N | 0.681 | 0.485 | 0.235664433957 | gnomAD-3.1.2 | 7.89E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.16234E-03 | None | 9.42E-05 | 0 | 1.47E-05 | 8.28844E-04 | 0 |
R/Q | 20311 | Fn3-35 | 41 | rs373062007 | 0.2682 | -0.976 | 1.0 | N | 0.681 | 0.485 | 0.235664433957 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
R/Q | 20311 | Fn3-35 | 41 | rs373062007 | 0.2682 | -0.976 | 1.0 | N | 0.681 | 0.485 | 0.235664433957 | gnomAD-4.0.0 | 4.60382E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.4839E-04 | None | 4.69616E-05 | 1.65837E-04 | 6.8095E-06 | 3.5264E-04 | 1.60808E-04 |
R/C | 20609 | Fn3-37 | 41 | rs786205389 | 0.7764 | None | 1.0 | N | 0.895 | 0.456 | 0.627389779515 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
R/C | 20609 | Fn3-37 | 41 | rs786205389 | 0.7764 | None | 1.0 | N | 0.895 | 0.456 | 0.627389779515 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
R/C | 20609 | Fn3-37 | 41 | rs786205389 | 0.7764 | None | 1.0 | N | 0.895 | 0.456 | 0.627389779515 | gnomAD-4.0.0 | 4.15323E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08667E-05 | 1.09801E-05 | 9.60892E-05 |
R/H | 20609 | Fn3-37 | 41 | rs372546292 | 0.7139 | -2.435 | 1.0 | N | 0.768 | 0.506 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 1.29216E-04 | 8.71E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/H | 20609 | Fn3-37 | 41 | rs372546292 | 0.7139 | -2.435 | 1.0 | N | 0.768 | 0.506 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 7.25E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/H | 20609 | Fn3-37 | 41 | rs372546292 | 0.7139 | -2.435 | 1.0 | N | 0.768 | 0.506 | None | gnomAD-4.0.0 | 1.30178E-05 | None | None | None | None | N | None | 4.00812E-05 | 6.67267E-05 | None | 0 | 0 | None | 0 | 0 | 1.1021E-05 | 0 | 1.60143E-05 |
R/S | 20708 | Fn3-38 | 41 | rs377175428 | 0.9291 | -2.108 | 0.201 | N | 0.446 | 0.192 | 0.200317383148 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
R/S | 20708 | Fn3-38 | 41 | rs377175428 | 0.9291 | -2.108 | 0.201 | N | 0.446 | 0.192 | 0.200317383148 | gnomAD-4.0.0 | 4.10639E-06 | None | None | None | None | N | None | 0 | 2.23714E-05 | None | 0 | 0 | None | 0 | 0 | 3.59857E-06 | 0 | 1.65684E-05 |
C/S | 20904 | Fn3-39 | 41 | rs866862450 | 0.7556 | -1.617 | 0.904 | N | 0.645 | 0.388 | 0.566408210792 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
C/S | 20904 | Fn3-39 | 41 | rs866862450 | 0.7556 | -1.617 | 0.904 | N | 0.645 | 0.388 | 0.566408210792 | gnomAD-4.0.0 | 1.59817E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86115E-06 | 0 | 0 |
K/N | 21003 | Fn3-40 | 41 | rs794729472 | 0.9718 | None | 1.0 | N | 0.741 | 0.28 | 0.215869574891 | gnomAD-4.0.0 | 7.52863E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.89611E-06 | 0 | 0 |
R/C | 21306 | Fn3-42 | 41 | rs773942316 | 0.7137 | -1.667 | 1.0 | N | 0.898 | 0.46 | 0.590936018357 | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.28818E-04 | None | 0 | 8.94E-06 | 0 |
R/C | 21306 | Fn3-42 | 41 | rs773942316 | 0.7137 | -1.667 | 1.0 | N | 0.898 | 0.46 | 0.590936018357 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07727E-04 | 0 |
R/C | 21306 | Fn3-42 | 41 | rs773942316 | 0.7137 | -1.667 | 1.0 | N | 0.898 | 0.46 | 0.590936018357 | gnomAD-4.0.0 | 1.98411E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23924E-06 | 2.85513E-04 | 1.60226E-05 |
R/H | 21306 | Fn3-42 | 41 | rs202240487 | 0.594 | -2.232 | 1.0 | N | 0.76 | 0.445 | None | gnomAD-2.1.1 | 1.53426E-03 | None | None | None | None | N | None | 4.14E-05 | 2.84E-05 | None | 0 | 0 | None | 1.33041E-02 | None | 0 | 1.33578E-04 | 2.81532E-04 |
R/H | 21306 | Fn3-42 | 41 | rs202240487 | 0.594 | -2.232 | 1.0 | N | 0.76 | 0.445 | None | gnomAD-3.1.2 | 5.00013E-04 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47124E-04 | 1.3278E-02 | 0 |
R/H | 21306 | Fn3-42 | 41 | rs202240487 | 0.594 | -2.232 | 1.0 | N | 0.76 | 0.445 | None | 1000 genomes | 3.19489E-03 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1.64E-02 | None |
R/H | 21306 | Fn3-42 | 41 | rs202240487 | 0.594 | -2.232 | 1.0 | N | 0.76 | 0.445 | None | gnomAD-4.0.0 | 9.64633E-04 | None | None | None | None | N | None | 6.67022E-05 | 6.672E-05 | None | 0 | 0 | None | 0 | 0 | 2.56895E-04 | 1.31556E-02 | 7.36731E-04 |
R/L | 21306 | Fn3-42 | 41 | rs202240487 | 0.9146 | -0.935 | 1.0 | N | 0.78 | 0.507 | 0.573237765134 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/L | 21306 | Fn3-42 | 41 | rs202240487 | 0.9146 | -0.935 | 1.0 | N | 0.78 | 0.507 | 0.573237765134 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 21306 | Fn3-42 | 41 | rs202240487 | 0.9146 | -0.935 | 1.0 | N | 0.78 | 0.507 | 0.573237765134 | gnomAD-4.0.0 | 3.09994E-06 | None | None | None | None | N | None | 4.00855E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.20431E-05 |
C/R | 21600 | Fn3-44 | 42 | rs1436243584 | 0.4184 | -1.038 | 0.99 | N | 0.795 | 0.42 | 0.726150275566 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
C/R | 21600 | Fn3-44 | 42 | rs1436243584 | 0.4184 | -1.038 | 0.99 | N | 0.795 | 0.42 | 0.726150275566 | gnomAD-4.0.0 | 1.36869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73551E-04 | 0 | 1.1595E-05 | 0 |
C/F | 21797 | Fn3-46 | 41 | rs886042894 | 0.2636 | None | 0.863 | N | 0.747 | 0.279 | 0.727300299738 | gnomAD-4.0.0 | 4.80084E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.40467E-06 | 0 | 1.66118E-05 |
C/G | 21797 | Fn3-46 | 41 | rs375830234 | 0.2986 | -1.928 | 0.002 | N | 0.627 | 0.273 | None | gnomAD-2.1.1 | 6.17E-05 | None | None | None | None | N | None | 6.66E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.2756E-04 | 0 |
C/G | 21797 | Fn3-46 | 41 | rs375830234 | 0.2986 | -1.928 | 0.002 | N | 0.627 | 0.273 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.0295E-04 | 0 | 0 |
C/G | 21797 | Fn3-46 | 41 | rs375830234 | 0.2986 | -1.928 | 0.002 | N | 0.627 | 0.273 | None | gnomAD-4.0.0 | 5.15397E-05 | None | None | None | None | N | None | 2.67201E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78957E-05 | 0 | 1.60488E-05 |
C/Y | 21797 | Fn3-46 | 41 | rs886042894 | 0.3236 | None | 0.975 | N | 0.727 | 0.32 | 0.637172401323 | gnomAD-4.0.0 | 2.0575E-06 | None | None | None | None | N | None | 0 | 4.50796E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.66118E-05 |
R/C | 21996 | Fn3-47 | 41 | rs577114038 | 0.7714 | -1.705 | 0.252 | N | 0.468 | 0.369 | None | gnomAD-2.1.1 | 1.07438E-04 | None | None | None | None | N | None | 4.14E-05 | 5.67247E-04 | None | 0 | 0 | None | 0 | None | 0 | 6.27E-05 | 1.40885E-04 |
R/C | 21996 | Fn3-47 | 41 | rs577114038 | 0.7714 | -1.705 | 0.252 | N | 0.468 | 0.369 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 9.65E-05 | 1.31079E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 21996 | Fn3-47 | 41 | rs577114038 | 0.7714 | -1.705 | 0.252 | N | 0.468 | 0.369 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/C | 21996 | Fn3-47 | 41 | rs577114038 | 0.7714 | -1.705 | 0.252 | N | 0.468 | 0.369 | None | gnomAD-4.0.0 | 4.89799E-05 | None | None | None | None | N | None | 1.06707E-04 | 4.67025E-04 | None | 0 | 0 | None | 0 | 1.6518E-04 | 3.30693E-05 | 1.09849E-05 | 3.20318E-05 |
R/H | 21996 | Fn3-47 | 41 | rs374489349 | 0.8354 | -2.535 | 1.0 | N | 0.533 | 0.469 | None | gnomAD-2.1.1 | 3.58E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.19E-05 | None | 0 | None | 0 | 5.49E-05 | 2.81928E-04 |
R/H | 21996 | Fn3-47 | 41 | rs374489349 | 0.8354 | -2.535 | 1.0 | N | 0.533 | 0.469 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 0 | 0 |
R/H | 21996 | Fn3-47 | 41 | rs374489349 | 0.8354 | -2.535 | 1.0 | N | 0.533 | 0.469 | None | gnomAD-4.0.0 | 4.58827E-05 | None | None | None | None | N | None | 1.33604E-05 | 1.66839E-05 | None | 0 | 4.47808E-05 | None | 0 | 0 | 5.76585E-05 | 0 | 3.20451E-05 |
R/Q | 22095 | Fn3-48 | 41 | rs745677076 | 0.5188 | -1.237 | 0.994 | N | 0.544 | 0.338 | 0.267299060538 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 1.1162E-04 | None | 3.27E-05 | None | 0 | 2.67E-05 | 0 |
R/Q | 22095 | Fn3-48 | 41 | rs745677076 | 0.5188 | -1.237 | 0.994 | N | 0.544 | 0.338 | 0.267299060538 | gnomAD-4.0.0 | 6.16E-06 | None | None | None | None | N | None | 5.98122E-05 | 0 | None | 0 | 2.52105E-05 | None | 0 | 0 | 3.59865E-06 | 1.15953E-05 | 1.65722E-05 |
R/W | 22095 | Fn3-48 | 41 | rs571093313 | 0.8666 | -0.879 | 1.0 | N | 0.721 | 0.46 | 0.443285836454 | gnomAD-2.1.1 | 6.86E-05 | None | None | None | None | N | None | 0 | 3.18896E-04 | None | 0 | 2.79205E-04 | None | 0 | None | 0 | 8.92E-06 | 0 |
R/W | 22095 | Fn3-48 | 41 | rs571093313 | 0.8666 | -0.879 | 1.0 | N | 0.721 | 0.46 | 0.443285836454 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 5.83885E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/W | 22095 | Fn3-48 | 41 | rs571093313 | 0.8666 | -0.879 | 1.0 | N | 0.721 | 0.46 | 0.443285836454 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
R/W | 22095 | Fn3-48 | 41 | rs571093313 | 0.8666 | -0.879 | 1.0 | N | 0.721 | 0.46 | 0.443285836454 | gnomAD-4.0.0 | 2.54191E-05 | None | None | None | None | N | None | 0 | 2.50183E-04 | None | 0 | 1.33929E-04 | None | 0 | 1.98282E-03 | 5.08713E-06 | 0 | 3.20246E-05 |
R/C | 22394 | Fn3-50 | 41 | rs1388705607 | 0.8097 | None | 1.0 | N | 0.9 | 0.6 | 0.578489777024 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 22394 | Fn3-50 | 41 | rs1388705607 | 0.8097 | None | 1.0 | N | 0.9 | 0.6 | 0.578489777024 | gnomAD-4.0.0 | 1.23976E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47817E-07 | 1.09796E-05 | 0 |
R/H | 22394 | Fn3-50 | 41 | rs777333661 | 0.6691 | -2.602 | 1.0 | N | 0.778 | 0.553 | 0.427940940899 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/H | 22394 | Fn3-50 | 41 | rs777333661 | 0.6691 | -2.602 | 1.0 | N | 0.778 | 0.553 | 0.427940940899 | gnomAD-4.0.0 | 1.02657E-05 | None | None | None | None | N | None | 2.99079E-05 | 0 | None | 0 | 0 | None | 0 | 1.73611E-04 | 1.16959E-05 | 0 | 0 |
R/P | 22394 | Fn3-50 | 41 | None | 0.9991 | None | 1.0 | D | 0.895 | 0.586 | 0.525258673147 | gnomAD-4.0.0 | 6.84381E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99683E-07 | 0 | 0 |
R/S | 22394 | Fn3-50 | 41 | None | 0.9946 | None | 1.0 | N | 0.787 | 0.561 | 0.415055319159 | gnomAD-4.0.0 | 6.84381E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1595E-05 | 0 |
R/G | 22881 | Fn3-54 | 41 | None | 0.7342 | None | 0.71 | N | 0.532 | 0.381 | 0.470484629704 | gnomAD-4.0.0 | 9.58267E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25953E-05 | 0 | 0 |
R/Q | 22881 | Fn3-54 | 41 | rs772700244 | 0.1753 | -1.407 | 0.068 | N | 0.274 | 0.211 | 0.163833314356 | gnomAD-2.1.1 | 3.63E-05 | None | None | None | None | N | None | 0 | 1.16131E-04 | None | 0 | 5.6E-05 | None | 3.27E-05 | None | 0 | 2.68E-05 | 0 |
R/Q | 22881 | Fn3-54 | 41 | rs772700244 | 0.1753 | -1.407 | 0.068 | N | 0.274 | 0.211 | 0.163833314356 | gnomAD-4.0.0 | 1.71113E-05 | None | None | None | None | N | None | 0 | 8.94734E-05 | None | 0 | 2.52512E-05 | None | 1.87631E-05 | 3.47464E-04 | 1.34947E-05 | 1.15993E-05 | 1.65717E-05 |
R/K | 23080 | Fn3-55 | 41 | rs949990037 | 0.5558 | -1.414 | 0.025 | N | 0.194 | 0.26 | 0.280181792013 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/K | 23080 | Fn3-55 | 41 | rs949990037 | 0.5558 | -1.414 | 0.025 | N | 0.194 | 0.26 | 0.280181792013 | gnomAD-4.0.0 | 1.59216E-06 | None | None | None | None | N | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/G | 23179 | Fn3-56 | 41 | None | 0.8808 | None | 0.117 | N | 0.519 | 0.359 | 0.385743280973 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
R/K | 23179 | Fn3-56 | 41 | None | 0.1382 | None | None | N | 0.156 | 0.102 | 0.250039746154 | gnomAD-4.0.0 | 2.73712E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.93963E-04 | 0 | 0 | 0 |
R/T | 23179 | Fn3-56 | 41 | rs763091757 | 0.9324 | -1.734 | 0.117 | N | 0.483 | 0.23 | 0.286465849087 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/T | 23179 | Fn3-56 | 41 | rs763091757 | 0.9324 | -1.734 | 0.117 | N | 0.483 | 0.23 | 0.286465849087 | gnomAD-4.0.0 | 2.73712E-06 | None | None | None | None | N | None | 0 | 6.70841E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65673E-05 |
R/C | 23475 | Fn3-58 | 41 | rs761442543 | 0.8427 | -2.027 | 1.0 | N | 0.754 | 0.471 | 0.612445847935 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 3.13E-05 | 1.40489E-04 |
R/C | 23475 | Fn3-58 | 41 | rs761442543 | 0.8427 | -2.027 | 1.0 | N | 0.754 | 0.471 | 0.612445847935 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
R/C | 23475 | Fn3-58 | 41 | rs761442543 | 0.8427 | -2.027 | 1.0 | N | 0.754 | 0.471 | 0.612445847935 | gnomAD-4.0.0 | 2.66528E-05 | None | None | None | None | N | None | 0 | 3.33545E-05 | None | 0 | 0 | None | 0 | 0 | 3.39089E-05 | 1.09796E-05 | 0 |
R/H | 23475 | Fn3-58 | 41 | rs370257707 | 0.791 | -2.676 | 0.999 | N | 0.587 | 0.41 | None | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 5.15E-05 | None | 0 | None | 0 | 4.7E-05 | 0 |
R/H | 23475 | Fn3-58 | 41 | rs370257707 | 0.791 | -2.676 | 0.999 | N | 0.587 | 0.41 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.36E-05 | 0 | 0 |
R/H | 23475 | Fn3-58 | 41 | rs370257707 | 0.791 | -2.676 | 0.999 | N | 0.587 | 0.41 | None | gnomAD-4.0.0 | 7.37575E-05 | None | None | None | None | N | None | 1.33526E-05 | 0 | None | 0 | 2.23254E-05 | None | 0 | 0 | 9.40973E-05 | 0 | 9.6083E-05 |
Q/H | 23572 | Fn3-59 | 41 | rs747703704 | 0.6004 | -1.415 | 1.0 | N | 0.697 | 0.449 | 0.241664281697 | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.14192E-04 | None | 0 | None | 0 | 0 | 0 |
Q/H | 23572 | Fn3-59 | 41 | rs747703704 | 0.6004 | -1.415 | 1.0 | N | 0.697 | 0.449 | 0.241664281697 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.86548E-04 | None | 0 | 0 | 0 | 0 | 0 |
Q/H | 23572 | Fn3-59 | 41 | rs747703704 | 0.6004 | -1.415 | 1.0 | N | 0.697 | 0.449 | 0.241664281697 | gnomAD-4.0.0 | 6.84288E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1595E-05 | 0 |
R/Q | 23767 | Fn3-60 | 42 | rs370516890 | 0.3939 | -1.456 | 1.0 | N | 0.677 | 0.451 | None | gnomAD-2.1.1 | 1.07924E-04 | None | None | None | None | N | None | 1.6592E-04 | 0 | None | 0 | 5.19E-05 | None | 6.55E-05 | None | 4.01E-05 | 1.73831E-04 | 0 |
R/Q | 23767 | Fn3-60 | 42 | rs370516890 | 0.3939 | -1.456 | 1.0 | N | 0.677 | 0.451 | None | gnomAD-3.1.2 | 1.18429E-04 | None | None | None | None | N | None | 2.17381E-04 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.17661E-04 | 0 | 0 |
R/Q | 23767 | Fn3-60 | 42 | rs370516890 | 0.3939 | -1.456 | 1.0 | N | 0.677 | 0.451 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/Q | 23767 | Fn3-60 | 42 | rs370516890 | 0.3939 | -1.456 | 1.0 | N | 0.677 | 0.451 | None | gnomAD-4.0.0 | 1.09125E-04 | None | None | None | None | N | None | 1.60034E-04 | 1.66789E-05 | None | 0 | 0 | None | 1.56514E-05 | 0 | 1.2634E-04 | 7.69197E-05 | 9.61138E-05 |
R/W | 23767 | Fn3-60 | 42 | rs532157196 | 0.8951 | -1.141 | 1.0 | N | 0.888 | 0.563 | 0.465806656444 | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | N | None | 6.49E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
R/W | 23767 | Fn3-60 | 42 | rs532157196 | 0.8951 | -1.141 | 1.0 | N | 0.888 | 0.563 | 0.465806656444 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/W | 23767 | Fn3-60 | 42 | rs532157196 | 0.8951 | -1.141 | 1.0 | N | 0.888 | 0.563 | 0.465806656444 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/W | 23767 | Fn3-60 | 42 | rs532157196 | 0.8951 | -1.141 | 1.0 | N | 0.888 | 0.563 | 0.465806656444 | gnomAD-4.0.0 | 5.58005E-06 | None | None | None | None | N | None | 4.00053E-05 | 0 | None | 0 | 2.23884E-05 | None | 0 | 0 | 3.39164E-06 | 0 | 1.60174E-05 |
R/K | 23964 | Fn3-62 | 41 | rs770679732 | 0.1198 | -1.275 | 0.046 | N | 0.211 | 0.148 | 0.231873229951 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/K | 23964 | Fn3-62 | 41 | rs770679732 | 0.1198 | -1.275 | 0.046 | N | 0.211 | 0.148 | 0.231873229951 | gnomAD-4.0.0 | 1.59287E-06 | None | None | None | None | N | None | 0 | 2.28728E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/C | 24163 | Fn3-63 | 42 | rs778284888 | 0.6731 | -1.685 | 1.0 | N | 0.795 | 0.415 | 0.709351898144 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.87687E-04 | 0 | 0 |
R/C | 24163 | Fn3-63 | 42 | rs778284888 | 0.6731 | -1.685 | 1.0 | N | 0.795 | 0.415 | 0.709351898144 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93648E-04 | None | 9.43E-05 | 0 | 0 | 0 | 0 |
R/C | 24163 | Fn3-63 | 42 | rs778284888 | 0.6731 | -1.685 | 1.0 | N | 0.795 | 0.415 | 0.709351898144 | gnomAD-4.0.0 | 1.39829E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.5901E-05 | None | 1.66141E-05 | 0 | 1.33022E-05 | 2.87002E-05 | 1.73503E-05 |
R/G | 24163 | Fn3-63 | 42 | None | 0.9642 | None | 0.954 | N | 0.643 | 0.509 | 0.691025755046 | gnomAD-4.0.0 | 7.40859E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.01654E-05 | 0 | 0 | 0 | 0 |
R/H | 24163 | Fn3-63 | 42 | rs374712231 | 0.7766 | -2.46 | 0.997 | N | 0.595 | 0.573 | None | gnomAD-2.1.1 | 3.48E-05 | None | None | None | None | N | None | 8.64E-05 | 0 | None | 0 | 6.07E-05 | None | 7.27E-05 | None | 0 | 3.01E-05 | 0 |
R/H | 24163 | Fn3-63 | 42 | rs374712231 | 0.7766 | -2.46 | 0.997 | N | 0.595 | 0.573 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 3.87297E-04 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
R/H | 24163 | Fn3-63 | 42 | rs374712231 | 0.7766 | -2.46 | 0.997 | N | 0.595 | 0.573 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 1E-03 | None | None | None | 0 | None |
R/H | 24163 | Fn3-63 | 42 | rs374712231 | 0.7766 | -2.46 | 0.997 | N | 0.595 | 0.573 | None | gnomAD-4.0.0 | 4.93351E-05 | None | None | None | None | N | None | 1.25874E-04 | 0 | None | 0 | 9.20217E-05 | None | 0 | 0 | 5.14811E-05 | 2.89243E-05 | 1.73557E-05 |
R/L | 24163 | Fn3-63 | 42 | rs374712231 | 0.9414 | -1.027 | 0.954 | N | 0.643 | 0.532 | None | gnomAD-2.1.1 | 9.93E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2E-05 | 0 |
R/L | 24163 | Fn3-63 | 42 | rs374712231 | 0.9414 | -1.027 | 0.954 | N | 0.643 | 0.532 | None | gnomAD-4.0.0 | 1.48394E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.8892E-06 | 0 | 0 |
R/S | 24163 | Fn3-63 | 42 | None | 0.9936 | None | 0.954 | N | 0.621 | 0.485 | 0.473065174198 | gnomAD-4.0.0 | 2.22258E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.83116E-06 | 0 | 0 |
R/C | 24262 | Fn3-64 | 41 | rs576976296 | 0.4297 | -1.584 | 1.0 | N | 0.759 | 0.401 | 0.613436686781 | gnomAD-2.1.1 | 1.82E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.13E-05 | None | 0 | 2.84E-05 | 0 |
R/C | 24262 | Fn3-64 | 41 | rs576976296 | 0.4297 | -1.584 | 1.0 | N | 0.759 | 0.401 | 0.613436686781 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 2.07727E-04 | 0 |
R/C | 24262 | Fn3-64 | 41 | rs576976296 | 0.4297 | -1.584 | 1.0 | N | 0.759 | 0.401 | 0.613436686781 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
R/C | 24262 | Fn3-64 | 41 | rs576976296 | 0.4297 | -1.584 | 1.0 | N | 0.759 | 0.401 | 0.613436686781 | gnomAD-4.0.0 | 4.5562E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25303E-06 | 1.29992E-05 | 0 |
R/H | 24262 | Fn3-64 | 41 | rs372390659 | 0.2335 | -2.116 | 0.385 | N | 0.263 | 0.264 | None | gnomAD-2.1.1 | 4.09E-05 | None | None | None | None | N | None | 4.26E-05 | 0 | None | 0 | 0 | None | 1.84049E-04 | None | 0 | 4.74E-05 | 0 |
R/H | 24262 | Fn3-64 | 41 | rs372390659 | 0.2335 | -2.116 | 0.385 | N | 0.263 | 0.264 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 2.07297E-04 | 0 |
R/H | 24262 | Fn3-64 | 41 | rs372390659 | 0.2335 | -2.116 | 0.385 | N | 0.263 | 0.264 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
R/H | 24262 | Fn3-64 | 41 | rs372390659 | 0.2335 | -2.116 | 0.385 | N | 0.263 | 0.264 | None | gnomAD-4.0.0 | 2.7327E-05 | None | None | None | None | N | None | 1.37756E-05 | 0 | None | 0 | 0 | None | 0 | 1.75747E-04 | 2.71316E-05 | 1.03839E-04 | 1.69045E-05 |
R/S | 24262 | Fn3-64 | 41 | None | 0.9778 | None | 0.975 | N | 0.597 | 0.346 | 0.350088858571 | gnomAD-4.0.0 | 7.2233E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.30868E-07 | 0 | 0 |
R/Q | 24559 | Fn3-66 | 41 | rs780238881 | 0.817 | -1.267 | 1.0 | N | 0.673 | 0.434 | 0.304435445954 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.30967E-04 | None | 0 | 1.78E-05 | 0 |
R/Q | 24559 | Fn3-66 | 41 | rs780238881 | 0.817 | -1.267 | 1.0 | N | 0.673 | 0.434 | 0.304435445954 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/Q | 24559 | Fn3-66 | 41 | rs780238881 | 0.817 | -1.267 | 1.0 | N | 0.673 | 0.434 | 0.304435445954 | gnomAD-4.0.0 | 1.86088E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.56607E-04 | None | 0 | 0 | 4.24193E-06 | 1.64813E-04 | 4.80815E-05 |
R/W | 24559 | Fn3-66 | 41 | rs367904757 | 0.961 | -0.937 | 1.0 | N | 0.888 | 0.53 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
R/W | 24559 | Fn3-66 | 41 | rs367904757 | 0.961 | -0.937 | 1.0 | N | 0.888 | 0.53 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/W | 24559 | Fn3-66 | 41 | rs367904757 | 0.961 | -0.937 | 1.0 | N | 0.888 | 0.53 | None | gnomAD-4.0.0 | 6.20327E-06 | None | None | None | None | N | None | 5.34559E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.09029E-06 | 0 | 0 |
Q/K | 24656 | Fn3-67 | 41 | rs763473286 | 0.166 | -0.2 | 0.999 | N | 0.479 | 0.409 | 0.254244900254 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
Q/K | 24656 | Fn3-67 | 41 | rs763473286 | 0.166 | -0.2 | 0.999 | N | 0.479 | 0.409 | 0.254244900254 | gnomAD-4.0.0 | 1.59216E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78211E-05 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 24849 | Fn3-68 | 42 | None | 0.9419 | None | 0.954 | N | 0.606 | 0.501 | 0.516050471323 | gnomAD-4.0.0 | 6.84466E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.53062E-05 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 24849 | Fn3-68 | 42 | rs745488276 | 0.5676 | -1.306 | 0.59 | N | 0.317 | 0.362 | 0.229924730088 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 0 | 1.16239E-04 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.8E-05 | 0 |
R/Q | 24849 | Fn3-68 | 42 | rs745488276 | 0.5676 | -1.306 | 0.59 | N | 0.317 | 0.362 | 0.229924730088 | gnomAD-4.0.0 | 9.5825E-06 | None | None | None | None | N | None | 0 | 8.94815E-05 | None | 0 | 0 | None | 0 | 0 | 7.19694E-06 | 1.15964E-05 | 1.65772E-05 |
R/W | 24849 | Fn3-68 | 42 | rs727503562 | 0.9001 | -1.061 | 1.0 | N | 0.671 | 0.571 | 0.369495900351 | gnomAD-2.1.1 | 2.51E-05 | None | None | None | None | N | None | 2.07159E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.58E-05 | 0 |
R/W | 24849 | Fn3-68 | 42 | rs727503562 | 0.9001 | -1.061 | 1.0 | N | 0.671 | 0.571 | 0.369495900351 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 1.44872E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/W | 24849 | Fn3-68 | 42 | rs727503562 | 0.9001 | -1.061 | 1.0 | N | 0.671 | 0.571 | 0.369495900351 | gnomAD-4.0.0 | 9.29914E-06 | None | None | None | None | N | None | 1.20221E-04 | 0 | None | 0 | 0 | None | 0 | 1.64636E-04 | 3.39105E-06 | 1.09808E-05 | 0 |
K/T | 24948 | Fn3-69 | 41 | rs1263875134 | 0.9865 | None | 0.988 | D | 0.741 | 0.476 | 0.397691132334 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
K/T | 24948 | Fn3-69 | 41 | rs1263875134 | 0.9865 | None | 0.988 | D | 0.741 | 0.476 | 0.397691132334 | gnomAD-4.0.0 | 2.56321E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78785E-06 | 0 | 0 |
K/E | 25046 | Fn3-70 | 41 | None | 0.7687 | None | 0.805 | N | 0.457 | 0.228 | 0.260735089382 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
K/R | 25046 | Fn3-70 | 41 | None | 0.0808 | None | 0.025 | N | 0.381 | 0.1 | 0.27855597813 | gnomAD-4.0.0 | 1.36871E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79931E-06 | 0 | 0 |
K/T | 25046 | Fn3-70 | 41 | rs759445513 | 0.8492 | -1.796 | 0.967 | N | 0.659 | 0.396 | 0.363356657567 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
R/K | 25245 | Fn3-71 | 42 | rs397517701 | 0.4567 | -1.461 | 0.944 | N | 0.459 | 0.205 | None | gnomAD-2.1.1 | 2.51E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 4.73E-05 | 0 |
R/K | 25245 | Fn3-71 | 42 | rs397517701 | 0.4567 | -1.461 | 0.944 | N | 0.459 | 0.205 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/K | 25245 | Fn3-71 | 42 | rs397517701 | 0.4567 | -1.461 | 0.944 | N | 0.459 | 0.205 | None | gnomAD-4.0.0 | 1.61187E-05 | None | None | None | None | N | None | 1.33547E-05 | 0 | None | 0 | 0 | None | 0 | 1.64582E-04 | 1.69549E-05 | 3.29417E-05 | 1.60195E-05 |
R/T | 25245 | Fn3-71 | 42 | rs397517701 | 0.9833 | -1.706 | 0.892 | N | 0.601 | 0.545 | 0.467585353272 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
R/T | 25245 | Fn3-71 | 42 | rs397517701 | 0.9833 | -1.706 | 0.892 | N | 0.601 | 0.545 | 0.467585353272 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/T | 25245 | Fn3-71 | 42 | rs397517701 | 0.9833 | -1.706 | 0.892 | N | 0.601 | 0.545 | 0.467585353272 | gnomAD-4.0.0 | 2.47979E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39097E-06 | 0 | 0 |
R/L | 25344 | Fn3-72 | 41 | rs556179271 | 0.8636 | -1.088 | 0.954 | N | 0.645 | 0.478 | 0.354822389136 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
R/L | 25344 | Fn3-72 | 41 | rs556179271 | 0.8636 | -1.088 | 0.954 | N | 0.645 | 0.478 | 0.354822389136 | gnomAD-4.0.0 | 4.10606E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39754E-06 | 0 | 0 |
R/P | 25344 | Fn3-72 | 41 | rs556179271 | 0.999 | -1.67 | 0.993 | D | 0.759 | 0.488 | 0.489036454283 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
R/Q | 25344 | Fn3-72 | 41 | None | 0.3882 | -1.166 | 0.994 | N | 0.571 | 0.335 | 0.300449992093 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
R/Q | 25344 | Fn3-72 | 41 | None | 0.3882 | -1.166 | 0.994 | N | 0.571 | 0.335 | 0.300449992093 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 3.27783E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 25344 | Fn3-72 | 41 | None | 0.3882 | -1.166 | 0.994 | N | 0.571 | 0.335 | 0.300449992093 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
R/Q | 25344 | Fn3-72 | 41 | None | 0.3882 | -1.166 | 0.994 | N | 0.571 | 0.335 | 0.300449992093 | gnomAD-4.0.0 | 1.48754E-05 | None | None | None | None | N | None | 0 | 2.0006E-04 | None | 0 | 2.23244E-05 | None | 0 | 0 | 8.47759E-06 | 0 | 1.60097E-05 |
R/W | 25344 | Fn3-72 | 41 | rs371696090 | 0.6834 | -0.831 | 1.0 | N | 0.703 | 0.473 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 9.81E-05 | None | 0 | 8.91E-06 | 0 |
R/W | 25344 | Fn3-72 | 41 | rs371696090 | 0.6834 | -0.831 | 1.0 | N | 0.703 | 0.473 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.44E-05 | 0 | 0 | 0 | 0 |
R/W | 25344 | Fn3-72 | 41 | rs371696090 | 0.6834 | -0.831 | 1.0 | N | 0.703 | 0.473 | None | gnomAD-4.0.0 | 6.81864E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23164E-05 | None | 1.56323E-05 | 0 | 2.54328E-06 | 6.58877E-05 | 0 |
C/Y | 25445 | Fn3-73 | 41 | rs2154168053 | 0.2623 | None | 0.99 | N | 0.727 | 0.381 | 0.686824916271 | gnomAD-4.0.0 | 1.3003E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7092E-05 | 0 | 0 |
R/C | 25641 | Fn3-74 | 41 | rs549745098 | 0.6887 | -1.903 | 1.0 | N | 0.782 | 0.473 | 0.670176712172 | gnomAD-2.1.1 | 2.05E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23864E-04 | None | 0 | None | 0 | 9E-06 | 0 |
R/C | 25641 | Fn3-74 | 41 | rs549745098 | 0.6887 | -1.903 | 1.0 | N | 0.782 | 0.473 | 0.670176712172 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93424E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 25641 | Fn3-74 | 41 | rs549745098 | 0.6887 | -1.903 | 1.0 | N | 0.782 | 0.473 | 0.670176712172 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
R/C | 25641 | Fn3-74 | 41 | rs549745098 | 0.6887 | -1.903 | 1.0 | N | 0.782 | 0.473 | 0.670176712172 | gnomAD-4.0.0 | 6.84366E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.93296E-05 | None | 0 | 0 | 5.94943E-06 | 0 | 0 |
R/H | 25641 | Fn3-74 | 41 | rs369707906 | 0.6865 | -2.602 | 0.999 | N | 0.569 | 0.45 | None | gnomAD-2.1.1 | 6.31795E-04 | None | None | None | None | N | None | 4.15E-05 | 0 | None | 0 | 0 | None | 5.74398E-03 | None | 0 | 3.17E-05 | 1.43802E-04 |
R/H | 25641 | Fn3-74 | 41 | rs369707906 | 0.6865 | -2.602 | 0.999 | N | 0.569 | 0.45 | None | gnomAD-3.1.2 | 2.89348E-04 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 7.45033E-03 | 0 |
R/H | 25641 | Fn3-74 | 41 | rs369707906 | 0.6865 | -2.602 | 0.999 | N | 0.569 | 0.45 | None | 1000 genomes | 1.99681E-03 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1.02E-02 | None |
R/H | 25641 | Fn3-74 | 41 | rs369707906 | 0.6865 | -2.602 | 0.999 | N | 0.569 | 0.45 | None | gnomAD-4.0.0 | 4.96591E-04 | None | None | None | None | N | None | 1.20588E-04 | 0 | None | 0 | 0 | None | 0 | 1.66168E-04 | 2.02316E-04 | 5.84711E-03 | 4.02188E-04 |
R/L | 25641 | Fn3-74 | 41 | None | 0.9417 | None | 0.996 | N | 0.679 | 0.454 | 0.681492719615 | gnomAD-4.0.0 | 6.87392E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87913E-05 | 0 | 0 | 0 | 0 |
Q/K | 25738 | Fn3-75 | 41 | None | 0.1368 | None | 0.984 | N | 0.431 | 0.208 | 0.1749357433 | gnomAD-4.0.0 | 6.8438E-07 | None | None | None | None | N | None | 2.99025E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/C | 26128 | Fn3-78 | 41 | rs373530641 | 0.3537 | -1.557 | 1.0 | N | 0.758 | 0.42 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
R/C | 26128 | Fn3-78 | 41 | rs373530641 | 0.3537 | -1.557 | 1.0 | N | 0.758 | 0.42 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/C | 26128 | Fn3-78 | 41 | rs373530641 | 0.3537 | -1.557 | 1.0 | N | 0.758 | 0.42 | None | gnomAD-4.0.0 | 2.48008E-05 | None | None | None | None | N | None | 2.6713E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.71363E-05 | 1.09825E-05 | 8.01025E-05 |
R/H | 26128 | Fn3-78 | 41 | rs757957389 | 0.3482 | -2.097 | 0.999 | N | 0.613 | 0.266 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 5.15E-05 | None | 0 | None | 0 | 7.84E-06 | 0 |
R/H | 26128 | Fn3-78 | 41 | rs757957389 | 0.3482 | -2.097 | 0.999 | N | 0.613 | 0.266 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 9.65E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/H | 26128 | Fn3-78 | 41 | rs757957389 | 0.3482 | -2.097 | 0.999 | N | 0.613 | 0.266 | None | gnomAD-4.0.0 | 9.30003E-06 | None | None | None | None | N | None | 6.67735E-05 | 1.66856E-05 | None | 0 | 2.23174E-05 | None | 0 | 0 | 5.93605E-06 | 0 | 1.60195E-05 |
R/L | 26128 | Fn3-78 | 41 | None | 0.6874 | None | 0.975 | N | 0.681 | 0.46 | 0.524533156562 | gnomAD-4.0.0 | 6.84556E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15977E-05 | 0 |
R/P | 26128 | Fn3-78 | 41 | rs757957389 | 0.9977 | -1.229 | 0.996 | N | 0.797 | 0.492 | 0.450248222533 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11769E-04 | None | 0 | None | 0 | 0 | 0 |
R/S | 26128 | Fn3-78 | 41 | None | 0.9456 | None | 0.975 | N | 0.643 | 0.388 | 0.358340041657 | gnomAD-4.0.0 | 1.36911E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79976E-06 | 0 | 0 |
R/L | 26327 | Fn3-79 | 42 | None | 0.9806 | None | 0.913 | N | 0.608 | 0.51 | 0.592397689306 | gnomAD-4.0.0 | 6.8433E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15953E-05 | 0 |
R/Q | 26327 | Fn3-79 | 42 | rs370367786 | 0.7777 | -1.144 | 0.999 | N | 0.475 | 0.425 | None | gnomAD-2.1.1 | 3.94E-05 | None | None | None | None | N | None | 8.27E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 6.28E-05 | 0 |
R/Q | 26327 | Fn3-79 | 42 | rs370367786 | 0.7777 | -1.144 | 0.999 | N | 0.475 | 0.425 | None | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 1.20697E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 4.78469E-04 |
R/Q | 26327 | Fn3-79 | 42 | rs370367786 | 0.7777 | -1.144 | 0.999 | N | 0.475 | 0.425 | None | gnomAD-4.0.0 | 5.20647E-05 | None | None | None | None | N | None | 9.34929E-05 | 3.33478E-05 | None | 0 | 0 | None | 0 | 0 | 6.18852E-05 | 0 | 3.20297E-05 |
R/I | 26426 | Fn3-80 | 41 | None | 0.9638 | None | 0.983 | D | 0.797 | 0.506 | 0.596373027241 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
R/C | 26723 | Fn3-82 | 41 | rs1412497882 | 0.8844 | -1.993 | 1.0 | N | 0.754 | 0.508 | 0.359357374593 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.91E-06 | 0 |
R/C | 26723 | Fn3-82 | 41 | rs1412497882 | 0.8844 | -1.993 | 1.0 | N | 0.754 | 0.508 | 0.359357374593 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 26723 | Fn3-82 | 41 | rs1412497882 | 0.8844 | -1.993 | 1.0 | N | 0.754 | 0.508 | 0.359357374593 | gnomAD-4.0.0 | 1.36352E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.5623E-05 | 0 | 1.44108E-05 | 2.19582E-05 | 3.20266E-05 |
R/H | 26723 | Fn3-82 | 41 | rs371615296 | 0.8407 | -2.7 | 0.999 | N | 0.584 | 0.534 | None | gnomAD-2.1.1 | 2.14E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.91E-05 | 1.40568E-04 |
R/H | 26723 | Fn3-82 | 41 | rs371615296 | 0.8407 | -2.7 | 0.999 | N | 0.584 | 0.534 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 1.20668E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/H | 26723 | Fn3-82 | 41 | rs371615296 | 0.8407 | -2.7 | 0.999 | N | 0.584 | 0.534 | None | gnomAD-4.0.0 | 1.6114E-05 | None | None | None | None | N | None | 6.67628E-05 | 0 | None | 3.37929E-05 | 0 | None | 0 | 1.64582E-04 | 9.32447E-06 | 3.29366E-05 | 8.00692E-05 |
R/L | 26723 | Fn3-82 | 41 | None | 0.9732 | None | 0.986 | N | 0.641 | 0.506 | 0.345859378078 | gnomAD-4.0.0 | 6.84275E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99543E-07 | 0 | 0 |
Q/K | 26820 | Fn3-83 | 41 | None | 0.1679 | None | 0.982 | N | 0.502 | 0.3 | 0.227260227426 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
R/L | 27013 | Fn3-84 | 42 | rs376374751 | 0.9496 | -1.124 | 0.922 | N | 0.614 | 0.445 | 0.48300943003 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
R/L | 27013 | Fn3-84 | 42 | rs376374751 | 0.9496 | -1.124 | 0.922 | N | 0.614 | 0.445 | 0.48300943003 | gnomAD-4.0.0 | 6.84288E-07 | None | None | None | None | N | None | 2.989E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 27013 | Fn3-84 | 42 | rs376374751 | 0.6212 | -1.349 | 0.447 | N | 0.33 | 0.298 | None | gnomAD-2.1.1 | 5.72E-05 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 9.68E-05 | 0 | None | 0 | None | 4E-05 | 9.39E-05 | 0 |
R/Q | 27013 | Fn3-84 | 42 | rs376374751 | 0.6212 | -1.349 | 0.447 | N | 0.33 | 0.298 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 7.25E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
R/Q | 27013 | Fn3-84 | 42 | rs376374751 | 0.6212 | -1.349 | 0.447 | N | 0.33 | 0.298 | None | gnomAD-4.0.0 | 4.52448E-05 | None | None | None | None | N | None | 8.01496E-05 | 1.66767E-05 | None | 0 | 0 | None | 1.56216E-05 | 4.93746E-04 | 4.91663E-05 | 0 | 6.40512E-05 |
K/E | 27112 | Fn3-85 | 41 | rs534444792 | 0.9855 | -1.074 | 0.958 | N | 0.447 | 0.397 | 0.374255764437 | gnomAD-2.1.1 | 8.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.57E-05 | None | 0 | 0 | 0 |
K/E | 27112 | Fn3-85 | 41 | rs534444792 | 0.9855 | -1.074 | 0.958 | N | 0.447 | 0.397 | 0.374255764437 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06954E-04 | 0 |
K/E | 27112 | Fn3-85 | 41 | rs534444792 | 0.9855 | -1.074 | 0.958 | N | 0.447 | 0.397 | 0.374255764437 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
K/E | 27112 | Fn3-85 | 41 | rs534444792 | 0.9855 | -1.074 | 0.958 | N | 0.447 | 0.397 | 0.374255764437 | gnomAD-4.0.0 | 5.13197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.02576E-05 | 2.84884E-05 |
K/T | 27112 | Fn3-85 | 41 | None | 0.99 | None | 0.988 | N | 0.731 | 0.511 | 0.447410926215 | gnomAD-4.0.0 | 1.5946E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86305E-06 | 0 | 0 |
K/E | 27210 | Fn3-86 | 41 | None | 0.8395 | None | 0.892 | N | 0.431 | 0.236 | 0.28492961333 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
K/T | 27210 | Fn3-86 | 41 | rs1241055435 | 0.8915 | -1.256 | 0.967 | N | 0.708 | 0.409 | 0.349429436713 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
K/T | 27210 | Fn3-86 | 41 | rs1241055435 | 0.8915 | -1.256 | 0.967 | N | 0.708 | 0.409 | 0.349429436713 | gnomAD-4.0.0 | 1.59473E-06 | None | None | None | None | N | None | 0 | 2.29674E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 27410 | Fn3-87 | 42 | None | 0.5222 | None | 0.025 | N | 0.198 | 0.212 | 0.229924730088 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
R/P | 27509 | Fn3-88 | 41 | rs1246168127 | 0.998 | None | 1.0 | D | 0.887 | 0.476 | 0.564872276104 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93274E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/P | 27509 | Fn3-88 | 41 | rs1246168127 | 0.998 | None | 1.0 | D | 0.887 | 0.476 | 0.564872276104 | gnomAD-4.0.0 | 6.57601E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93274E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 27509 | Fn3-88 | 41 | rs1246168127 | 0.3526 | -1.083 | 1.0 | N | 0.687 | 0.42 | 0.358744678677 | gnomAD-2.1.1 | 3.62E-05 | None | None | None | None | N | None | 0 | 2.31723E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
R/Q | 27509 | Fn3-88 | 41 | rs1246168127 | 0.3526 | -1.083 | 1.0 | N | 0.687 | 0.42 | 0.358744678677 | gnomAD-4.0.0 | 6.15789E-06 | None | None | None | None | N | None | 0 | 1.56523E-04 | None | 0 | 0 | None | 0 | 0 | 1.79897E-06 | 0 | 0 |
R/Q | 27806 | Fn3-90 | 41 | rs192301247 | 0.5384 | -1.143 | 1.0 | N | 0.675 | 0.421 | None | gnomAD-2.1.1 | 1.27E-05 | None | None | None | None | N | None | 0 | 6.25E-05 | None | 0 | 0 | None | 0 | None | 0 | 9.17E-06 | 0 |
R/Q | 27806 | Fn3-90 | 41 | rs192301247 | 0.5384 | -1.143 | 1.0 | N | 0.675 | 0.421 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 4.41E-05 | 2.06954E-04 | 0 |
R/Q | 27806 | Fn3-90 | 41 | rs192301247 | 0.5384 | -1.143 | 1.0 | N | 0.675 | 0.421 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
R/Q | 27806 | Fn3-90 | 41 | rs192301247 | 0.5384 | -1.143 | 1.0 | N | 0.675 | 0.421 | None | gnomAD-4.0.0 | 1.00189E-05 | None | None | None | None | N | None | 1.35186E-05 | 3.50373E-05 | None | 0 | 2.24004E-05 | None | 0 | 0 | 8.5275E-06 | 2.28133E-05 | 0 |
R/C | 28491 | Fn3-95 | 42 | rs746090724 | 0.3034 | -1.83 | 1.0 | N | 0.761 | 0.412 | 0.635445006688 | gnomAD-2.1.1 | 5.37E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 4.57666E-04 | None | 0 | 0 | 0 |
R/C | 28491 | Fn3-95 | 42 | rs746090724 | 0.3034 | -1.83 | 1.0 | N | 0.761 | 0.412 | 0.635445006688 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.31182E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 28491 | Fn3-95 | 42 | rs746090724 | 0.3034 | -1.83 | 1.0 | N | 0.761 | 0.412 | 0.635445006688 | gnomAD-4.0.0 | 2.16931E-05 | None | None | None | None | N | None | 0 | 5.00367E-05 | None | 0 | 0 | None | 0 | 0 | 2.54291E-06 | 3.18408E-04 | 0 |
R/H | 28491 | Fn3-95 | 42 | rs373129706 | 0.3997 | -2.483 | 0.997 | D | 0.584 | 0.524 | None | gnomAD-2.1.1 | 1.10946E-04 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 1.23571E-03 | None | 6.54E-05 | None | 0 | 3.14E-05 | 0 |
R/H | 28491 | Fn3-95 | 42 | rs373129706 | 0.3997 | -2.483 | 0.997 | D | 0.584 | 0.524 | None | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.5444E-03 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/H | 28491 | Fn3-95 | 42 | rs373129706 | 0.3997 | -2.483 | 0.997 | D | 0.584 | 0.524 | None | gnomAD-4.0.0 | 5.82597E-05 | None | None | None | None | N | None | 2.67008E-05 | 0 | None | 0 | 8.70303E-04 | None | 0 | 0 | 3.56E-05 | 9.88207E-05 | 3.20277E-05 |
R/L | 28590 | Fn3-96 | 41 | None | 0.8126 | None | 1.0 | N | 0.737 | 0.577 | 0.706951834606 | gnomAD-4.0.0 | 2.05277E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69845E-06 | 0 | 0 |
R/P | 28590 | Fn3-96 | 41 | rs375667028 | 0.9983 | -1.536 | 1.0 | D | 0.871 | 0.691 | 0.692726414735 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
R/P | 28590 | Fn3-96 | 41 | rs375667028 | 0.9983 | -1.536 | 1.0 | D | 0.871 | 0.691 | 0.692726414735 | gnomAD-4.0.0 | 6.84258E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52258E-05 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 28590 | Fn3-96 | 41 | rs375667028 | 0.2997 | -1.037 | 1.0 | N | 0.666 | 0.485 | None | gnomAD-2.1.1 | 1.25107E-04 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 3.27E-05 | None | 4.80461E-04 | 1.64255E-04 | 0 |
R/Q | 28590 | Fn3-96 | 41 | rs375667028 | 0.2997 | -1.037 | 1.0 | N | 0.666 | 0.485 | None | gnomAD-3.1.2 | 1.1834E-04 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 5.65504E-04 | 0 | 1.47054E-04 | 0 | 0 |
R/Q | 28590 | Fn3-96 | 41 | rs375667028 | 0.2997 | -1.037 | 1.0 | N | 0.666 | 0.485 | None | gnomAD-4.0.0 | 9.04842E-05 | None | None | None | None | N | None | 4.0047E-05 | 1.66733E-05 | None | 0 | 0 | None | 4.37623E-04 | 0 | 8.73066E-05 | 8.78522E-05 | 4.80415E-05 |
R/C | 28885 | Fn3-98 | 41 | rs1702802682 | 0.7668 | None | 1.0 | D | 0.901 | 0.43 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.43E-05 | 0 | 0 | 0 | 0 |
R/C | 28885 | Fn3-98 | 41 | rs1702802682 | 0.7668 | None | 1.0 | D | 0.901 | 0.43 | None | gnomAD-4.0.0 | 3.09877E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.68765E-05 | 0 | 1.6953E-06 | 0 | 0 |
R/H | 28885 | Fn3-98 | 41 | rs371539720 | 0.7392 | -2.547 | 1.0 | N | 0.766 | 0.492 | None | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 2.89911E-04 | 0 | None | 0 | None | 0 | 3.9E-05 | 0 |
R/H | 28885 | Fn3-98 | 41 | rs371539720 | 0.7392 | -2.547 | 1.0 | N | 0.766 | 0.492 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 4.83E-05 | 6.55E-05 | 0 | 2.88018E-04 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/H | 28885 | Fn3-98 | 41 | rs371539720 | 0.7392 | -2.547 | 1.0 | N | 0.766 | 0.492 | None | gnomAD-4.0.0 | 3.40854E-05 | None | None | None | None | N | None | 2.6703E-05 | 3.334E-05 | None | 2.0273E-04 | 0 | None | 0 | 0 | 3.47537E-05 | 1.09803E-05 | 4.80338E-05 |
R/L | 28885 | Fn3-98 | 41 | rs371539720 | 0.947 | -1.137 | 1.0 | N | 0.784 | 0.465 | 0.620522651735 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
R/L | 28885 | Fn3-98 | 41 | rs371539720 | 0.947 | -1.137 | 1.0 | N | 0.784 | 0.465 | 0.620522651735 | gnomAD-4.0.0 | 6.84255E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99518E-07 | 0 | 0 |
L/P | 28982 | Fn3-99 | 41 | rs767470225 | 0.9611 | None | 0.781 | N | 0.797 | 0.308 | 0.716020962526 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
R/G | 29178 | Fn3-100 | 42 | rs1214776587 | 0.9572 | -2.338 | 1.0 | N | 0.771 | 0.609 | 0.371157983038 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/G | 29178 | Fn3-100 | 42 | rs1214776587 | 0.9572 | -2.338 | 1.0 | N | 0.771 | 0.609 | 0.371157983038 | gnomAD-4.0.0 | 1.59103E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
K/N | 29277 | Fn3-101 | 41 | None | 0.9951 | None | 1.0 | N | 0.753 | 0.483 | 0.202086224978 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
R/C | 29375 | Fn3-102 | 41 | rs368439674 | 0.3844 | -1.62 | 0.998 | N | 0.622 | 0.426 | None | gnomAD-2.1.1 | 8.05E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 7.84753E-04 | None | 0 | None | 0 | 4.44E-05 | 0 |
R/C | 29375 | Fn3-102 | 41 | rs368439674 | 0.3844 | -1.62 | 0.998 | N | 0.622 | 0.426 | None | gnomAD-3.1.2 | 9.86E-05 | None | None | None | None | N | None | 0 | 6.5505E-04 | 0 | 0 | 1.9253E-04 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
R/C | 29375 | Fn3-102 | 41 | rs368439674 | 0.3844 | -1.62 | 0.998 | N | 0.622 | 0.426 | None | gnomAD-4.0.0 | 3.16057E-05 | None | None | None | None | N | None | 1.33472E-05 | 1.8337E-04 | None | 0 | 2.00947E-04 | None | 0 | 1.6442E-04 | 2.28846E-05 | 0 | 3.20225E-05 |
R/H | 29375 | Fn3-102 | 41 | rs761246441 | 0.2919 | -2.104 | 0.047 | N | 0.297 | 0.238 | 0.214338557667 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 1.16003E-04 | None | 0 | 1.12108E-04 | None | 0 | None | 0 | 0 | 0 |
R/H | 29375 | Fn3-102 | 41 | rs761246441 | 0.2919 | -2.104 | 0.047 | N | 0.297 | 0.238 | 0.214338557667 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 1.88786E-04 | 0 | 0 | 0 | 0 |
R/H | 29375 | Fn3-102 | 41 | rs761246441 | 0.2919 | -2.104 | 0.047 | N | 0.297 | 0.238 | 0.214338557667 | gnomAD-4.0.0 | 1.11551E-05 | None | None | None | None | N | None | 2.66987E-05 | 5.00083E-05 | None | 0 | 4.46568E-05 | None | 3.12617E-05 | 0 | 6.78063E-06 | 0 | 1.60118E-05 |
R/L | 29375 | Fn3-102 | 41 | rs761246441 | 0.7127 | None | 0.756 | N | 0.535 | 0.317 | 0.457286136841 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 29375 | Fn3-102 | 41 | rs761246441 | 0.7127 | None | 0.756 | N | 0.535 | 0.317 | 0.457286136841 | gnomAD-4.0.0 | 6.57289E-06 | None | None | None | None | N | None | 2.41359E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 29375 | Fn3-102 | 41 | None | 0.9549 | None | 0.756 | N | 0.452 | 0.351 | 0.330589388543 | gnomAD-4.0.0 | 6.84235E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99441E-07 | 0 | 0 |
R/C | 29574 | Fn3-103 | 42 | rs200513274 | 0.6076 | -1.687 | 1.0 | N | 0.885 | 0.374 | None | gnomAD-2.1.1 | 2.60645E-04 | None | None | None | None | N | None | 1.23957E-04 | 2.83E-05 | None | 0 | 4.10298E-04 | None | 2.61455E-04 | None | 0 | 3.98624E-04 | 2.80899E-04 |
R/C | 29574 | Fn3-103 | 42 | rs200513274 | 0.6076 | -1.687 | 1.0 | N | 0.885 | 0.374 | None | gnomAD-3.1.2 | 2.89283E-04 | None | None | None | None | N | None | 1.20691E-04 | 0 | 0 | 0 | 7.72201E-04 | None | 0 | 0 | 5.14555E-04 | 0 | 0 |
R/C | 29574 | Fn3-103 | 42 | rs200513274 | 0.6076 | -1.687 | 1.0 | N | 0.885 | 0.374 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
R/C | 29574 | Fn3-103 | 42 | rs200513274 | 0.6076 | -1.687 | 1.0 | N | 0.885 | 0.374 | None | gnomAD-4.0.0 | 4.75884E-04 | None | None | None | None | N | None | 1.06627E-04 | 0 | None | 0 | 3.79007E-04 | None | 1.56265E-05 | 0 | 5.8059E-04 | 3.51363E-04 | 4.00128E-04 |
R/G | 29574 | Fn3-103 | 42 | rs200513274 | 0.9637 | -2.568 | 1.0 | N | 0.783 | 0.466 | 0.614107689767 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/G | 29574 | Fn3-103 | 42 | rs200513274 | 0.9637 | -2.568 | 1.0 | N | 0.783 | 0.466 | 0.614107689767 | gnomAD-4.0.0 | 2.05251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79885E-06 | 1.15937E-05 | 0 |
R/H | 29574 | Fn3-103 | 42 | rs111727915 | 0.7671 | -2.472 | 1.0 | N | 0.787 | 0.404 | None | gnomAD-2.1.1 | 5.3912E-04 | None | None | None | None | N | None | 2.06629E-03 | 9.89819E-04 | None | 1.74149E-03 | 0 | None | 3.27E-05 | None | 4E-05 | 3.12627E-04 | 8.4246E-04 |
R/H | 29574 | Fn3-103 | 42 | rs111727915 | 0.7671 | -2.472 | 1.0 | N | 0.787 | 0.404 | None | gnomAD-3.1.2 | 8.74057E-04 | None | None | None | None | N | None | 2.05096E-03 | 1.30959E-03 | 0 | 1.72911E-03 | 0 | None | 0 | 0 | 3.0866E-04 | 0 | 4.78469E-04 |
R/H | 29574 | Fn3-103 | 42 | rs111727915 | 0.7671 | -2.472 | 1.0 | N | 0.787 | 0.404 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 1.5E-03 | 2.9E-03 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
R/H | 29574 | Fn3-103 | 42 | rs111727915 | 0.7671 | -2.472 | 1.0 | N | 0.787 | 0.404 | None | gnomAD-4.0.0 | 3.14762E-04 | None | None | None | None | N | None | 1.9855E-03 | 9.83071E-04 | None | 1.58773E-03 | 0 | None | 1.56226E-05 | 1.32013E-03 | 1.70361E-04 | 6.58733E-05 | 5.9219E-04 |
R/L | 29673 | Fn3-104 | 41 | rs200639218 | 0.7689 | -1.17 | 1.0 | N | 0.76 | 0.544 | 0.605592448911 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.46E-05 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
R/L | 29673 | Fn3-104 | 41 | rs200639218 | 0.7689 | -1.17 | 1.0 | N | 0.76 | 0.544 | 0.605592448911 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 29673 | Fn3-104 | 41 | rs200639218 | 0.7689 | -1.17 | 1.0 | N | 0.76 | 0.544 | 0.605592448911 | gnomAD-4.0.0 | 6.19677E-06 | None | None | None | None | N | None | 1.3349E-05 | 1.66678E-05 | None | 0 | 0 | None | 0 | 0 | 6.78073E-06 | 0 | 0 |
R/Q | 29673 | Fn3-104 | 41 | rs200639218 | 0.2547 | -1.499 | 1.0 | N | 0.676 | 0.382 | None | gnomAD-2.1.1 | 2.14378E-04 | None | None | None | None | N | None | 0 | 8.20089E-04 | None | 9.68E-05 | 5.12E-05 | None | 2.61438E-04 | None | 0 | 1.48747E-04 | 2.81136E-04 |
R/Q | 29673 | Fn3-104 | 41 | rs200639218 | 0.2547 | -1.499 | 1.0 | N | 0.676 | 0.382 | None | gnomAD-3.1.2 | 2.10308E-04 | None | None | None | None | N | None | 0 | 1.5713E-03 | 0 | 0 | 0 | None | 0 | 0 | 1.02902E-04 | 0 | 4.78927E-04 |
R/Q | 29673 | Fn3-104 | 41 | rs200639218 | 0.2547 | -1.499 | 1.0 | N | 0.676 | 0.382 | None | gnomAD-4.0.0 | 1.43146E-04 | None | None | None | None | N | None | 0 | 9.33396E-04 | None | 3.37861E-05 | 4.45633E-05 | None | 0 | 6.57678E-04 | 1.13577E-04 | 2.08599E-04 | 2.40161E-04 |
R/K | 29774 | Fn3-105 | 41 | rs750672440 | 0.112 | -1.432 | None | N | 0.147 | 0.094 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/K | 29774 | Fn3-105 | 41 | rs750672440 | 0.112 | -1.432 | None | N | 0.147 | 0.094 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20592E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 29774 | Fn3-105 | 41 | rs750672440 | 0.112 | -1.432 | None | N | 0.147 | 0.094 | None | gnomAD-4.0.0 | 6.19669E-06 | None | None | None | None | N | None | 1.20099E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 8.4758E-07 | 0 | 0 |
R/K | 29973 | Fn3-106 | 41 | rs1183482452 | 0.2496 | -1.527 | None | N | 0.15 | 0.111 | 0.21279746466 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 7.83E-06 | 0 |
R/K | 29973 | Fn3-106 | 41 | rs1183482452 | 0.2496 | -1.527 | None | N | 0.15 | 0.111 | 0.21279746466 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/K | 29973 | Fn3-106 | 41 | rs1183482452 | 0.2496 | -1.527 | None | N | 0.15 | 0.111 | 0.21279746466 | gnomAD-4.0.0 | 1.86077E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.6952E-06 | 1.09794E-05 | 0 |
R/T | 29973 | Fn3-106 | 41 | rs1183482452 | 0.9839 | None | 0.117 | N | 0.449 | 0.407 | 0.294918367191 | gnomAD-4.0.0 | 2.73955E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.63747E-05 | 0 |
K/R | 30070 | Fn3-107 | 41 | rs781508633 | 0.0747 | -0.728 | 0.046 | N | 0.161 | 0.089 | 0.282575091529 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.30719E-04 | None | 0 | 0 | 0 |
K/R | 30070 | Fn3-107 | 41 | rs781508633 | 0.0747 | -0.728 | 0.046 | N | 0.161 | 0.089 | 0.282575091529 | gnomAD-4.0.0 | 2.73667E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.47794E-05 | 1.6564E-05 |
R/G | 30265 | Fn3-108 | 42 | None | 0.9143 | None | 1.0 | N | 0.749 | 0.551 | 0.484329738948 | gnomAD-4.0.0 | 1.3685E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31976E-05 | 0 |
R/Q | 30265 | Fn3-108 | 42 | rs771164863 | 0.2942 | -1.009 | 1.0 | N | 0.685 | 0.505 | 0.312608672186 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
R/Q | 30265 | Fn3-108 | 42 | rs771164863 | 0.2942 | -1.009 | 1.0 | N | 0.685 | 0.505 | 0.312608672186 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 30265 | Fn3-108 | 42 | rs771164863 | 0.2942 | -1.009 | 1.0 | N | 0.685 | 0.505 | 0.312608672186 | gnomAD-4.0.0 | 9.91627E-06 | None | None | None | None | N | None | 1.33554E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.10196E-05 | 2.19717E-05 | 0 |
R/W | 30265 | Fn3-108 | 42 | rs200022152 | 0.7372 | -1.348 | 1.0 | N | 0.883 | 0.48 | None | gnomAD-2.1.1 | 9.29E-05 | None | None | None | None | N | None | 2.06629E-04 | 2.83E-05 | None | 0 | 0 | None | 9.82E-05 | None | 1.20221E-04 | 1.01551E-04 | 1.40489E-04 |
R/W | 30265 | Fn3-108 | 42 | rs200022152 | 0.7372 | -1.348 | 1.0 | N | 0.883 | 0.48 | None | gnomAD-3.1.2 | 1.44665E-04 | None | None | None | None | N | None | 2.89673E-04 | 0 | 0 | 0 | 0 | None | 2.82912E-04 | 0 | 7.35E-05 | 2.06868E-04 | 4.79386E-04 |
R/W | 30265 | Fn3-108 | 42 | rs200022152 | 0.7372 | -1.348 | 1.0 | N | 0.883 | 0.48 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/W | 30265 | Fn3-108 | 42 | rs200022152 | 0.7372 | -1.348 | 1.0 | N | 0.883 | 0.48 | None | gnomAD-4.0.0 | 8.11825E-05 | None | None | None | None | N | None | 2.93279E-04 | 1.66728E-05 | None | 0 | 0 | None | 9.37734E-05 | 1.65071E-04 | 7.54412E-05 | 8.78677E-05 | 6.40225E-05 |
K/N | 30364 | Fn3-109 | 41 | rs1395941923 | 0.9922 | -1.822 | 1.0 | N | 0.742 | 0.434 | 0.243972157842 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
K/N | 30364 | Fn3-109 | 41 | rs1395941923 | 0.9922 | -1.822 | 1.0 | N | 0.742 | 0.434 | 0.243972157842 | gnomAD-4.0.0 | 4.10514E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39667E-06 | 0 | 0 |
R/Q | 30462 | Fn3-110 | 41 | rs794729529 | 0.2774 | -1.001 | 1.0 | N | 0.69 | 0.444 | 0.28058544554 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 2.67E-05 | 0 |
R/Q | 30462 | Fn3-110 | 41 | rs794729529 | 0.2774 | -1.001 | 1.0 | N | 0.69 | 0.444 | 0.28058544554 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 2.07125E-04 | 0 |
R/Q | 30462 | Fn3-110 | 41 | rs794729529 | 0.2774 | -1.001 | 1.0 | N | 0.69 | 0.444 | 0.28058544554 | gnomAD-4.0.0 | 2.85122E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23204E-05 | None | 1.56294E-05 | 0 | 3.39085E-05 | 2.19597E-05 | 3.20287E-05 |
R/W | 30462 | Fn3-110 | 41 | rs373623340 | 0.6015 | -0.833 | 1.0 | N | 0.88 | 0.474 | None | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | N | None | 4.54959E-04 | 2.83E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.57E-05 | 0 |
R/W | 30462 | Fn3-110 | 41 | rs373623340 | 0.6015 | -0.833 | 1.0 | N | 0.88 | 0.474 | None | gnomAD-3.1.2 | 1.0523E-04 | None | None | None | None | N | None | 3.62301E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/W | 30462 | Fn3-110 | 41 | rs373623340 | 0.6015 | -0.833 | 1.0 | N | 0.88 | 0.474 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 2.3E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/W | 30462 | Fn3-110 | 41 | rs373623340 | 0.6015 | -0.833 | 1.0 | N | 0.88 | 0.474 | None | gnomAD-4.0.0 | 2.29324E-05 | None | None | None | None | N | None | 3.33431E-04 | 1.66733E-05 | None | 0 | 0 | None | 0 | 3.30142E-04 | 1.69542E-06 | 1.09815E-05 | 9.60523E-05 |
R/Q | 30660 | Fn3-111 | 42 | rs765986284 | 0.5938 | -1.055 | 1.0 | N | 0.695 | 0.486 | 0.260735089382 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 6.46E-05 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
R/Q | 30660 | Fn3-111 | 42 | rs765986284 | 0.5938 | -1.055 | 1.0 | N | 0.695 | 0.486 | 0.260735089382 | gnomAD-4.0.0 | 1.16322E-05 | None | None | None | None | N | None | 2.98846E-05 | 8.94574E-05 | None | 0 | 0 | None | 0 | 0 | 9.89458E-06 | 1.1595E-05 | 0 |
R/W | 30660 | Fn3-111 | 42 | rs377464325 | 0.9246 | -1.009 | 1.0 | N | 0.882 | 0.502 | None | gnomAD-2.1.1 | 1.78E-05 | None | None | None | None | N | None | 1.24018E-04 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.40371E-04 |
R/W | 30660 | Fn3-111 | 42 | rs377464325 | 0.9246 | -1.009 | 1.0 | N | 0.882 | 0.502 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.66E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/W | 30660 | Fn3-111 | 42 | rs377464325 | 0.9246 | -1.009 | 1.0 | N | 0.882 | 0.502 | None | gnomAD-4.0.0 | 1.17752E-05 | None | None | None | None | N | None | 1.3354E-04 | 6.67E-05 | None | 0 | 2.22926E-05 | None | 0 | 0 | 1.69528E-06 | 1.09815E-05 | 1.60123E-05 |
R/K | 30759 | Fn3-112 | 41 | rs769687279 | 0.2994 | -1.133 | 0.997 | N | 0.46 | 0.33 | 0.418344901717 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
R/K | 30759 | Fn3-112 | 41 | rs769687279 | 0.2994 | -1.133 | 0.997 | N | 0.46 | 0.33 | 0.418344901717 | gnomAD-4.0.0 | 1.59115E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 0 | 0 | 0 |
C/F | 30861 | Fn3-113 | 41 | None | 0.4502 | None | 0.949 | N | 0.74 | 0.335 | 0.705029066125 | gnomAD-4.0.0 | 1.36836E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79886E-06 | 0 | 0 |
C/R | 30861 | Fn3-113 | 41 | rs2154147860 | 0.2643 | None | 0.901 | N | 0.791 | 0.444 | 0.64097366104 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
C/Y | 30861 | Fn3-113 | 41 | rs1045877862 | 0.4743 | -1.623 | 0.983 | N | 0.745 | 0.344 | 0.735756410601 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
C/Y | 30861 | Fn3-113 | 41 | rs1045877862 | 0.4743 | -1.623 | 0.983 | N | 0.745 | 0.344 | 0.735756410601 | gnomAD-4.0.0 | 3.42089E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49716E-06 | 0 | 0 |
R/L | 31056 | Fn3-114 | 41 | None | 0.945 | None | 1.0 | N | 0.784 | 0.45 | 0.667105625577 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 31056 | Fn3-114 | 41 | None | 0.945 | None | 1.0 | N | 0.784 | 0.45 | 0.667105625577 | gnomAD-4.0.0 | 6.56668E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93199E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 31056 | Fn3-114 | 41 | rs201377736 | 0.548 | -1.044 | 1.0 | N | 0.685 | 0.384 | 0.231873229951 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.96335E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 31056 | Fn3-114 | 41 | rs201377736 | 0.548 | -1.044 | 1.0 | N | 0.685 | 0.384 | 0.231873229951 | gnomAD-4.0.0 | 8.67471E-06 | None | None | None | None | N | None | 3.99808E-05 | 4.99817E-05 | None | 0 | 0 | None | 0 | 0 | 5.93318E-06 | 0 | 1.60041E-05 |
R/G | 31153 | Fn3-115 | 41 | None | 0.7236 | None | 0.896 | N | 0.601 | 0.383 | 0.465721554213 | gnomAD-4.0.0 | 6.8417E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99439E-07 | 0 | 0 |
R/K | 31153 | Fn3-115 | 41 | None | 0.1057 | None | 0.011 | N | 0.115 | 0.124 | 0.252162846088 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
R/C | 31349 | Fn3-116 | 42 | rs727503549 | 0.521 | -2.001 | 1.0 | N | 0.845 | 0.499 | 0.65667953858 | gnomAD-2.1.1 | 8.93E-05 | None | None | None | None | N | None | 0 | 0 | None | 3.87222E-04 | 1.02617E-04 | None | 4.24809E-04 | None | 1.19894E-04 | 7.82E-06 | 2.80899E-04 |
R/C | 31349 | Fn3-116 | 42 | rs727503549 | 0.521 | -2.001 | 1.0 | N | 0.845 | 0.499 | 0.65667953858 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.43E-05 | 0 | 1.47E-05 | 2.07383E-04 | 4.78011E-04 |
R/C | 31349 | Fn3-116 | 42 | rs727503549 | 0.521 | -2.001 | 1.0 | N | 0.845 | 0.499 | 0.65667953858 | gnomAD-4.0.0 | 5.32947E-05 | None | None | None | None | N | None | 0 | 0 | None | 3.71622E-04 | 2.89842E-04 | None | 7.81128E-05 | 0 | 1.61042E-05 | 3.73298E-04 | 6.4043E-05 |
R/G | 31349 | Fn3-116 | 42 | rs727503549 | 0.9426 | -2.66 | 1.0 | N | 0.779 | 0.559 | 0.629010756219 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/H | 31349 | Fn3-116 | 42 | rs181104321 | 0.5146 | -2.395 | 1.0 | N | 0.715 | 0.405 | None | gnomAD-2.1.1 | 2.22519E-03 | None | None | None | None | N | None | 2.76951E-03 | 7.36002E-04 | None | 0 | 0 | None | 3.27E-05 | None | 1.41487E-02 | 1.22756E-03 | 2.5288E-03 |
R/H | 31349 | Fn3-116 | 42 | rs181104321 | 0.5146 | -2.395 | 1.0 | N | 0.715 | 0.405 | None | gnomAD-3.1.2 | 2.64279E-03 | None | None | None | None | N | None | 2.99329E-03 | 1.57377E-03 | 0 | 0 | 0 | None | 1.51658E-02 | 0 | 1.30836E-03 | 2.07039E-04 | 1.43403E-03 |
R/H | 31349 | Fn3-116 | 42 | rs181104321 | 0.5146 | -2.395 | 1.0 | N | 0.715 | 0.405 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | N | None | 8E-04 | 1.4E-03 | None | None | 0 | 4E-03 | None | None | None | 0 | None |
R/H | 31349 | Fn3-116 | 42 | rs181104321 | 0.5146 | -2.395 | 1.0 | N | 0.715 | 0.405 | None | gnomAD-4.0.0 | 1.71084E-03 | None | None | None | None | N | None | 2.81243E-03 | 9.66925E-04 | None | 0 | 0 | None | 1.32006E-02 | 3.29924E-04 | 1.32223E-03 | 1.09789E-04 | 1.20035E-03 |
R/L | 31349 | Fn3-116 | 42 | rs181104321 | 0.8767 | -1.325 | 1.0 | N | 0.779 | 0.475 | 0.565757058302 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
K/N | 31448 | Fn3-117 | 41 | rs1475927387 | 0.9982 | None | 1.0 | N | 0.735 | 0.434 | 0.268211541103 | gnomAD-4.0.0 | 1.36839E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79893E-06 | 0 | 0 |
K/Q | 31546 | Fn3-118 | 41 | rs746533506 | 0.3448 | -1.853 | 1.0 | N | 0.71 | 0.411 | 0.257786959452 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 1.29299E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/C | 31748 | Fn3-119 | 41 | rs142525903 | 0.6683 | -1.626 | 1.0 | N | 0.903 | 0.496 | None | gnomAD-2.1.1 | 9.89512E-04 | None | None | None | None | N | None | 1.23987E-03 | 4.24713E-04 | None | 1.69344E-02 | 0 | None | 3.27E-05 | None | 0 | 3.20628E-04 | 2.10615E-03 |
R/C | 31748 | Fn3-119 | 41 | rs142525903 | 0.6683 | -1.626 | 1.0 | N | 0.903 | 0.496 | None | gnomAD-3.1.2 | 7.42688E-04 | None | None | None | None | N | None | 8.68768E-04 | 2.61849E-04 | 0 | 1.49942E-02 | 0 | None | 0 | 0 | 2.2053E-04 | 0 | 2.87356E-03 |
R/C | 31748 | Fn3-119 | 41 | rs142525903 | 0.6683 | -1.626 | 1.0 | N | 0.903 | 0.496 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | N | None | 4.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/C | 31748 | Fn3-119 | 41 | rs142525903 | 0.6683 | -1.626 | 1.0 | N | 0.903 | 0.496 | None | gnomAD-4.0.0 | 5.91154E-04 | None | None | None | None | N | None | 1.23964E-03 | 3.99933E-04 | None | 1.67917E-02 | 0 | None | 0 | 3.63036E-03 | 1.72066E-04 | 1.09791E-05 | 1.8247E-03 |
R/H | 31748 | Fn3-119 | 41 | rs547575746 | 0.7752 | -2.626 | 1.0 | N | 0.762 | 0.678 | 0.403469152278 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
R/H | 31748 | Fn3-119 | 41 | rs547575746 | 0.7752 | -2.626 | 1.0 | N | 0.762 | 0.678 | 0.403469152278 | 1000 genomes | None | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/H | 31748 | Fn3-119 | 41 | rs547575746 | 0.7752 | -2.626 | 1.0 | N | 0.762 | 0.678 | 0.403469152278 | gnomAD-4.0.0 | 1.84739E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52054E-05 | None | 0 | 0 | 1.8889E-05 | 3.47802E-05 | 3.31334E-05 |
R/L | 31748 | Fn3-119 | 41 | None | 0.9406 | None | 1.0 | N | 0.779 | 0.68 | 0.602559457607 | gnomAD-4.0.0 | 6.84219E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99475E-07 | 0 | 0 |
R/S | 31748 | Fn3-119 | 41 | rs142525903 | 0.9928 | -1.926 | 1.0 | N | 0.773 | 0.559 | 0.403328974453 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/S | 31748 | Fn3-119 | 41 | rs142525903 | 0.9928 | -1.926 | 1.0 | N | 0.773 | 0.559 | 0.403328974453 | gnomAD-4.0.0 | 6.84216E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
R/C | 31847 | Fn3-120 | 41 | rs774814532 | 0.5596 | -1.7 | 1.0 | N | 0.919 | 0.535 | 0.437850553699 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 2.22568E-04 | None | 0 | None | 0 | 8.87E-06 | 0 |
R/C | 31847 | Fn3-120 | 41 | rs774814532 | 0.5596 | -1.7 | 1.0 | N | 0.919 | 0.535 | 0.437850553699 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92827E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/C | 31847 | Fn3-120 | 41 | rs774814532 | 0.5596 | -1.7 | 1.0 | N | 0.919 | 0.535 | 0.437850553699 | gnomAD-4.0.0 | 1.36341E-05 | None | None | None | None | N | None | 0 | 1.66706E-05 | None | 0 | 1.78245E-04 | None | 0 | 3.29056E-04 | 9.3242E-06 | 0 | 0 |
R/H | 31847 | Fn3-120 | 41 | rs771179752 | 0.3992 | -2.762 | 1.0 | N | 0.765 | 0.644 | None | gnomAD-2.1.1 | 4.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11272E-04 | None | 3.27E-05 | None | 1.39237E-04 | 3.55E-05 | 0 |
R/H | 31847 | Fn3-120 | 41 | rs771179752 | 0.3992 | -2.762 | 1.0 | N | 0.765 | 0.644 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/H | 31847 | Fn3-120 | 41 | rs771179752 | 0.3992 | -2.762 | 1.0 | N | 0.765 | 0.644 | None | gnomAD-4.0.0 | 4.46199E-05 | None | None | None | None | N | None | 0 | 1.66694E-05 | None | 0 | 3.11929E-04 | None | 7.80933E-05 | 6.58111E-04 | 3.8992E-05 | 2.19587E-05 | 0 |
R/P | 31847 | Fn3-120 | 41 | rs771179752 | 0.999 | None | 1.0 | D | 0.873 | 0.749 | 0.565354849907 | Rees (2021) | None | MmD | comp het with R5430* | None | None | N | Genetic analysis of TTN in 30 CM patients; comp het with truncating; Domain unfolded in vitro; cannot be re-folded | None | None | None | None | None | None | None | None | None | None | None |
R/P | 31847 | Fn3-120 | 41 | rs771179752 | 0.999 | None | 1.0 | D | 0.873 | 0.749 | 0.565354849907 | gnomAD-4.0.0 | 6.84237E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99523E-07 | 0 | 0 |
R/C | 32145 | Fn3-122 | 41 | rs878907981 | 0.8258 | -1.616 | 1.0 | N | 0.886 | 0.498 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14837E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/C | 32145 | Fn3-122 | 41 | rs878907981 | 0.8258 | -1.616 | 1.0 | N | 0.886 | 0.498 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/C | 32145 | Fn3-122 | 41 | rs878907981 | 0.8258 | -1.616 | 1.0 | N | 0.886 | 0.498 | None | gnomAD-4.0.0 | 5.58189E-06 | None | None | None | None | N | None | 4.00481E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23839E-06 | 1.09815E-05 | 0 |
R/H | 32145 | Fn3-122 | 41 | rs759948951 | 0.7837 | -2.274 | 1.0 | N | 0.761 | 0.553 | 0.38225645794 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 1.66778E-04 |
R/H | 32145 | Fn3-122 | 41 | rs759948951 | 0.7837 | -2.274 | 1.0 | N | 0.761 | 0.553 | 0.38225645794 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
R/H | 32145 | Fn3-122 | 41 | rs759948951 | 0.7837 | -2.274 | 1.0 | N | 0.761 | 0.553 | 0.38225645794 | gnomAD-4.0.0 | 1.30229E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23135E-05 | None | 0 | 0 | 1.52582E-05 | 1.09827E-05 | 1.60133E-05 |
C/Y | 32242 | Fn3-123 | 41 | None | 0.4298 | None | 0.995 | N | 0.751 | 0.4 | 0.750831387573 | gnomAD-4.0.0 | 8.40225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.18751E-06 | 0 | 0 |
R/C | 32440 | Fn3-124 | 42 | rs759932470 | 0.706 | -1.674 | 1.0 | N | 0.891 | 0.559 | 0.609718080597 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/C | 32440 | Fn3-124 | 42 | rs759932470 | 0.706 | -1.674 | 1.0 | N | 0.891 | 0.559 | 0.609718080597 | gnomAD-4.0.0 | 3.42133E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69855E-06 | 1.15939E-05 | 1.65667E-05 |
R/H | 32440 | Fn3-124 | 42 | rs750047570 | 0.7765 | -2.253 | 1.0 | N | 0.755 | 0.559 | 0.46512379133 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
R/H | 32440 | Fn3-124 | 42 | rs750047570 | 0.7765 | -2.253 | 1.0 | N | 0.755 | 0.559 | 0.46512379133 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/H | 32440 | Fn3-124 | 42 | rs750047570 | 0.7765 | -2.253 | 1.0 | N | 0.755 | 0.559 | 0.46512379133 | gnomAD-4.0.0 | 9.91604E-06 | None | None | None | None | N | None | 6.67539E-05 | 1.66717E-05 | None | 0 | 0 | None | 0 | 0 | 8.47659E-06 | 0 | 0 |
R/Q | 32836 | Fn3-127 | 42 | rs368312810 | 0.3077 | -1.034 | 1.0 | N | 0.679 | 0.409 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/Q | 32836 | Fn3-127 | 42 | rs368312810 | 0.3077 | -1.034 | 1.0 | N | 0.679 | 0.409 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 32836 | Fn3-127 | 42 | rs368312810 | 0.3077 | -1.034 | 1.0 | N | 0.679 | 0.409 | None | gnomAD-4.0.0 | 1.11546E-05 | None | None | None | None | N | None | 2.67108E-05 | 0 | None | 0 | 2.22816E-05 | None | 0 | 1.64474E-04 | 1.01712E-05 | 2.19558E-05 | 0 |
K/E | 32937 | Fn3-128 | 42 | rs200544701 | 0.8538 | -0.841 | 0.722 | N | 0.512 | 0.167 | None | gnomAD-2.1.1 | 1.96287E-04 | None | None | None | None | N | None | 0 | 5.09251E-04 | None | 2.90135E-03 | 0 | None | 6.54E-05 | None | 0 | 1.56E-05 | 4.20994E-04 |
K/E | 32937 | Fn3-128 | 42 | rs200544701 | 0.8538 | -0.841 | 0.722 | N | 0.512 | 0.167 | None | gnomAD-3.1.2 | 1.05169E-04 | None | None | None | None | N | None | 0 | 2.62089E-04 | 0 | 2.59366E-03 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
K/E | 32937 | Fn3-128 | 42 | rs200544701 | 0.8538 | -0.841 | 0.722 | N | 0.512 | 0.167 | None | gnomAD-4.0.0 | 9.17171E-05 | None | None | None | None | N | None | 1.33501E-05 | 4.66838E-04 | None | 2.80424E-03 | 0 | None | 0 | 0 | 2.11908E-05 | 2.19573E-05 | 1.44106E-04 |
R/I | 33038 | Fn3-129 | 41 | None | 0.9841 | None | 1.0 | N | 0.885 | 0.537 | 0.842324735218 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
C/R | 33331 | Fn3-130 | 42 | rs56061641 | 0.0914 | -0.874 | 0.001 | N | 0.44 | 0.241 | None | gnomAD-2.1.1 | 2.61592E-04 | None | None | None | None | N | None | 2.90505E-04 | 6.53595E-04 | None | 0 | 0 | None | 3.61319E-04 | None | 0 | 2.03816E-04 | 8.44832E-04 |
C/R | 33331 | Fn3-130 | 42 | rs56061641 | 0.0914 | -0.874 | 0.001 | N | 0.44 | 0.241 | None | gnomAD-3.1.2 | 2.95885E-04 | None | None | None | None | N | None | 9.66E-05 | 1.1794E-03 | 0 | 0 | 0 | None | 0 | 1.58228E-02 | 1.91137E-04 | 2.07297E-04 | 1.91571E-03 |
C/R | 33331 | Fn3-130 | 42 | rs56061641 | 0.0914 | -0.874 | 0.001 | N | 0.44 | 0.241 | None | 1000 genomes | 1.39776E-03 | None | None | None | None | N | None | 5.3E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
C/R | 33331 | Fn3-130 | 42 | rs56061641 | 0.0914 | -0.874 | 0.001 | N | 0.44 | 0.241 | None | gnomAD-4.0.0 | 2.12603E-04 | None | None | None | None | N | None | 2.5336E-04 | 7.3419E-04 | None | 0 | 0 | None | 0 | 1.35269E-02 | 1.17835E-04 | 3.62613E-04 | 4.1632E-04 |
C/S | 33331 | Fn3-130 | 42 | rs56061641 | 0.4716 | None | 0.425 | N | 0.511 | 0.199 | 0.511790803624 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
C/S | 33331 | Fn3-130 | 42 | rs56061641 | 0.4716 | None | 0.425 | N | 0.511 | 0.199 | 0.511790803624 | gnomAD-4.0.0 | 2.47952E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.3909E-06 | 0 | 0 |
R/C | 33432 | Fn3-131 | 41 | rs878882035 | 0.3593 | None | 1.0 | D | 0.87 | 0.431 | 0.630346058385 | gnomAD-4.0.0 | 3.20381E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87778E-06 | 1.4445E-05 | 0 |
R/G | 33432 | Fn3-131 | 41 | None | 0.8767 | None | 1.0 | N | 0.798 | 0.526 | 0.636843794314 | gnomAD-4.0.0 | 1.60191E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4445E-05 | 0 |
R/H | 33432 | Fn3-131 | 41 | rs374876608 | 0.3864 | -2.17 | 1.0 | N | 0.742 | 0.437 | None | gnomAD-2.1.1 | 5.76E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.53941E-04 | None | 2.98567E-04 | None | 0 | 2.37E-05 | 1.41884E-04 |
R/H | 33432 | Fn3-131 | 41 | rs374876608 | 0.3864 | -2.17 | 1.0 | N | 0.742 | 0.437 | None | gnomAD-3.1.2 | 1.70814E-04 | None | None | None | None | N | None | 0 | 0 | 2.30263E-02 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
R/H | 33432 | Fn3-131 | 41 | rs374876608 | 0.3864 | -2.17 | 1.0 | N | 0.742 | 0.437 | None | gnomAD-4.0.0 | 5.65062E-05 | None | None | None | None | N | None | 2.67544E-05 | 3.34672E-05 | None | 0 | 6.68598E-05 | None | 0 | 1.64853E-04 | 3.14121E-05 | 2.64696E-04 | 1.60503E-05 |
C/Y | 33729 | Fn3-132 | 41 | None | 0.709 | None | 0.999 | N | 0.707 | 0.403 | 0.704489790954 | gnomAD-4.0.0 | 1.59115E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85794E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.