Structural position:
- Domain Type: Fn3
- Aligned Position: 54
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| K/E | 15700 |
Fn3-1 |
44 | rs2057727269 |
0.7329 | None | 0.41 | N | 0.473 | 0.227 | 0.257786959452 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 15700 |
Fn3-1 |
44 | rs752235858 |
0.866 | -0.016 | 0.83 | N | 0.565 | 0.169 | 0.199424873507 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 8.72E-05 | None | 0 | 1.12473E-04 | None | 0 | None | 0 | 0 | 0 |
| K/N | 15700 |
Fn3-1 |
44 | rs752235858 |
0.866 | -0.016 | 0.83 | N | 0.565 | 0.169 | 0.199424873507 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.95008E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 15700 |
Fn3-1 |
44 | rs752235858 |
0.866 | -0.016 | 0.83 | N | 0.565 | 0.169 | 0.199424873507 | gnomAD-4.0.0 | 3.72101E-06 | None | None | None | None | N | None | 0 | 5.01119E-05 | None | 0 | 6.71622E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 15700 |
Fn3-1 |
44 | None | 0.1085 | None | 0.01 | N | 0.289 | 0.135 | 0.272639205421 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 15801 |
Fn3-2 |
44 | rs148808516 |
0.2387 | 0.08 | 0.901 | N | 0.395 | 0.28 | None | gnomAD-2.1.1 | 4.43E-05 | None | None | None | None | N | None | 3.23248E-04 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 3.56E-05 | 0 |
| T/I | 15801 |
Fn3-2 |
44 | rs148808516 |
0.2387 | 0.08 | 0.901 | N | 0.395 | 0.28 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 9.66E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| T/I | 15801 |
Fn3-2 |
44 | rs148808516 |
0.2387 | 0.08 | 0.901 | N | 0.395 | 0.28 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 3.8E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/I | 15801 |
Fn3-2 |
44 | rs148808516 |
0.2387 | 0.08 | 0.901 | N | 0.395 | 0.28 | None | gnomAD-4.0.0 | 1.30219E-05 | None | None | None | None | N | None | 9.3428E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.48096E-06 | 2.1966E-05 | 3.20461E-05 |
| G/E | 15902 |
Fn3-3 |
44 | rs561284948 |
0.2308 | -0.623 | 0.989 | N | 0.532 | 0.352 | None | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 3.10256E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/E | 15902 |
Fn3-3 |
44 | rs561284948 |
0.2308 | -0.623 | 0.989 | N | 0.532 | 0.352 | None | gnomAD-3.1.2 | 9.22E-05 | None | None | None | None | N | None | 2.657E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 4.78011E-04 |
| G/E | 15902 |
Fn3-3 |
44 | rs561284948 |
0.2308 | -0.623 | 0.989 | N | 0.532 | 0.352 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| G/E | 15902 |
Fn3-3 |
44 | rs561284948 |
0.2308 | -0.623 | 0.989 | N | 0.532 | 0.352 | None | gnomAD-4.0.0 | 1.57486E-05 | None | None | None | None | N | None | 2.44061E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 5.12806E-06 | 0 | 1.62644E-05 |
| G/R | 15902 |
Fn3-3 |
44 | rs1368589210 |
0.4509 | -0.16 | 1.0 | D | 0.689 | 0.407 | 0.604892984849 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.57895E-04 | None | 0 | None | 0 | 0 | 0 |
| G/R | 15902 |
Fn3-3 |
44 | rs1368589210 |
0.4509 | -0.16 | 1.0 | D | 0.689 | 0.407 | 0.604892984849 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9516E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 15902 |
Fn3-3 |
44 | rs1368589210 |
0.4509 | -0.16 | 1.0 | D | 0.689 | 0.407 | 0.604892984849 | gnomAD-4.0.0 | 6.58571E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.9516E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 15902 |
Fn3-3 |
44 | None | 0.4757 | None | 1.0 | D | 0.729 | 0.392 | 0.609718080597 | gnomAD-4.0.0 | 6.9664E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.07308E-07 | 0 | 0 |
| S/G | 16098 |
Fn3-4 |
44 | rs750949782 |
0.0867 | -0.522 | 0.055 | N | 0.407 | 0.091 | 0.110078149338 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/G | 16098 |
Fn3-4 |
44 | rs750949782 |
0.0867 | -0.522 | 0.055 | N | 0.407 | 0.091 | 0.110078149338 | gnomAD-4.0.0 | 3.18902E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86513E-06 | 1.43443E-05 | 0 |
| D/N | 16394 |
Fn3-6 |
44 | rs765265590 |
0.146 | 0.517 | 1.0 | N | 0.53 | 0.361 | 0.241078983079 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 5.82E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 16394 |
Fn3-6 |
44 | rs765265590 |
0.146 | 0.517 | 1.0 | N | 0.53 | 0.361 | 0.241078983079 | gnomAD-4.0.0 | 3.18734E-06 | None | None | None | None | N | None | 0 | 4.58379E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 16493 |
Fn3-7 |
44 | None | 0.3744 | None | 0.931 | N | 0.519 | 0.327 | 0.402471007487 | gnomAD-4.0.0 | 1.59363E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86338E-06 | 0 | 0 |
| R/K | 16694 |
Fn3-9 |
44 | rs779633258 |
0.4884 | 0.01 | 0.543 | N | 0.311 | 0.159 | None | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 6.51E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/K | 16694 |
Fn3-9 |
44 | rs779633258 |
0.4884 | 0.01 | 0.543 | N | 0.311 | 0.159 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 16694 |
Fn3-9 |
44 | rs779633258 |
0.4884 | 0.01 | 0.543 | N | 0.311 | 0.159 | None | gnomAD-4.0.0 | 6.58224E-06 | None | None | None | None | N | None | 2.41464E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/E | 17090 |
Fn3-12 |
44 | None | 0.8247 | None | 1.0 | N | 0.682 | 0.488 | 0.511220899679 | gnomAD-4.0.0 | 1.59281E-06 | None | None | None | None | N | None | 0 | 2.28697E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 17190 |
Fn3-13 |
44 | None | 0.1924 | None | 0.898 | N | 0.525 | 0.243 | 0.294918367191 | gnomAD-4.0.0 | 6.84462E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99785E-07 | 0 | 0 |
| G/V | 17190 |
Fn3-13 |
44 | None | 0.5316 | None | 1.0 | N | 0.775 | 0.38 | 0.475272412942 | gnomAD-4.0.0 | 1.36892E-06 | None | None | None | None | N | None | 5.98516E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/M | 17807 |
Fn3-17 |
44 | None | 0.6101 | None | 1.0 | N | 0.657 | 0.516 | 0.417208245017 | gnomAD-4.0.0 | 2.0535E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6994E-06 | 0 | 0 |
| K/R | 17807 |
Fn3-17 |
44 | None | 0.1103 | None | 0.999 | N | 0.632 | 0.26 | 0.257786959452 | gnomAD-4.0.0 | 6.845E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99798E-07 | 0 | 0 |
| K/T | 17807 |
Fn3-17 |
44 | rs747883893 |
0.4436 | -0.394 | 1.0 | N | 0.63 | 0.533 | 0.389596023526 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| K/T | 17807 |
Fn3-17 |
44 | rs747883893 |
0.4436 | -0.394 | 1.0 | N | 0.63 | 0.533 | 0.389596023526 | gnomAD-4.0.0 | 6.845E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15974E-05 | 0 |
| D/E | 17905 |
Fn3-18 |
44 | rs1366977449 |
0.4001 | 0.036 | 1.0 | N | 0.402 | 0.246 | 0.291694819147 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| D/E | 17905 |
Fn3-18 |
44 | rs1366977449 |
0.4001 | 0.036 | 1.0 | N | 0.402 | 0.246 | 0.291694819147 | gnomAD-3.1.2 | 6.67E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.48E-05 | 0 | 0 |
| D/E | 17905 |
Fn3-18 |
44 | rs1366977449 |
0.4001 | 0.036 | 1.0 | N | 0.402 | 0.246 | 0.291694819147 | gnomAD-4.0.0 | 1.92498E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6186E-06 | 0 | 0 |
| D/H | 17905 |
Fn3-18 |
44 | rs2054587701 |
0.7124 | None | 1.0 | D | 0.591 | 0.461 | 0.343334270461 | gnomAD-4.0.0 | 1.61822E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.08318E-05 |
| S/R | 18108 |
Fn3-19 |
44 | rs1460827160 |
0.6185 | None | 0.015 | N | 0.201 | 0.145 | 0.124217242631 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 18108 |
Fn3-19 |
44 | rs1460827160 |
0.6185 | None | 0.015 | N | 0.201 | 0.145 | 0.124217242631 | gnomAD-4.0.0 | 1.86085E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.5447E-06 | 0 | 0 |
| G/D | 18315 |
Fn3-21 |
44 | rs779940105 |
0.2501 | -0.23 | 1.0 | N | 0.573 | 0.5 | 0.343334270461 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.73E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/D | 18315 |
Fn3-21 |
44 | rs779940105 |
0.2501 | -0.23 | 1.0 | N | 0.573 | 0.5 | 0.343334270461 | gnomAD-4.0.0 | 2.05436E-06 | None | None | None | None | N | None | 0 | 6.72405E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 18315 |
Fn3-21 |
44 | None | 0.2171 | None | 1.0 | N | 0.619 | 0.423 | 0.338834610459 | gnomAD-4.0.0 | 1.36961E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.31719E-05 |
| D/E | 18522 |
Fn3-22 |
44 | None | 0.1392 | None | 0.012 | N | 0.289 | 0.063 | 0.168933306366 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/V | 18522 |
Fn3-22 |
44 | rs1211576470 |
0.3137 | 0.373 | 0.669 | N | 0.307 | 0.261 | 0.409533910539 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/V | 18522 |
Fn3-22 |
44 | rs1211576470 |
0.3137 | 0.373 | 0.669 | N | 0.307 | 0.261 | 0.409533910539 | gnomAD-4.0.0 | 1.59308E-06 | None | None | None | None | N | None | 0 | 2.28896E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/T | 18627 |
Fn3-23 |
49 | rs727503597 |
0.1968 | None | 0.001 | N | 0.093 | 0.181 | 0.247872288689 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/T | 18627 |
Fn3-23 |
49 | rs727503597 |
0.1968 | None | 0.001 | N | 0.093 | 0.181 | 0.247872288689 | gnomAD-4.0.0 | 1.42123E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.56654E-05 | 0 | 3.40321E-05 |
| N/D | 18828 |
Fn3-24 |
45 | None | 0.2161 | None | 0.928 | N | 0.419 | 0.242 | 0.227260227426 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 7.32654E-05 |
| N/T | 18828 |
Fn3-24 |
45 | rs71423569 |
0.1793 | None | 0.865 | N | 0.428 | 0.202 | 0.241078983079 | gnomAD-4.0.0 | 6.85974E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.66091E-05 |
| T/A | 18927 |
Fn3-25 |
44 | rs937956129 |
0.0903 | 0.014 | 0.726 | N | 0.516 | 0.273 | 0.200317383148 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| T/A | 18927 |
Fn3-25 |
44 | rs937956129 |
0.0903 | 0.014 | 0.726 | N | 0.516 | 0.273 | 0.200317383148 | gnomAD-4.0.0 | 1.36903E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99666E-07 | 0 | 1.65755E-05 |
| T/N | 18927 |
Fn3-25 |
44 | rs1432586088 |
0.1801 | 0.175 | 0.957 | N | 0.559 | 0.313 | 0.28798054836 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/N | 18927 |
Fn3-25 |
44 | rs1432586088 |
0.1801 | 0.175 | 0.957 | N | 0.559 | 0.313 | 0.28798054836 | gnomAD-4.0.0 | 1.5929E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43353E-05 | 0 |
| D/E | 19227 |
Fn3-27 |
45 | rs1440846373 |
0.1852 | -0.111 | 1.0 | N | 0.394 | 0.203 | 0.177238962908 | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.2E-06 | 0 |
| D/E | 19227 |
Fn3-27 |
45 | rs1440846373 |
0.1852 | -0.111 | 1.0 | N | 0.394 | 0.203 | 0.177238962908 | gnomAD-4.0.0 | 6.86601E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01297E-07 | 0 | 0 |
| M/T | 19621 |
Fn3-30 |
43 | None | 0.137 | None | 0.324 | N | 0.345 | 0.136 | 0.528761452848 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| M/V | 19621 |
Fn3-30 |
43 | None | 0.0998 | None | 0.165 | N | 0.361 | 0.175 | 0.495773158881 | gnomAD-4.0.0 | 1.59208E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85966E-06 | 0 | 0 |
| A/V | 19920 |
Fn3-32 |
44 | None | 0.1364 | None | 0.998 | N | 0.511 | 0.351 | 0.453679287548 | gnomAD-4.0.0 | 1.59311E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79065E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 20020 |
Fn3-33 |
44 | rs1430427636 |
0.1475 | -0.701 | 1.0 | N | 0.575 | 0.377 | 0.273938319068 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| G/D | 20020 |
Fn3-33 |
44 | rs1430427636 |
0.1475 | -0.701 | 1.0 | N | 0.575 | 0.377 | 0.273938319068 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 1.09649E-03 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 20020 |
Fn3-33 |
44 | rs1430427636 |
0.1475 | -0.701 | 1.0 | N | 0.575 | 0.377 | 0.273938319068 | gnomAD-4.0.0 | 3.71945E-06 | None | None | None | None | N | None | 0 | 1.66867E-05 | None | 0 | 0 | None | 0 | 0 | 3.39109E-06 | 0 | 0 |
| R/G | 20215 |
Fn3-34 |
45 | rs1223437077 |
0.1469 | None | 0.024 | N | 0.348 | 0.163 | 0.269111216191 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/G | 20215 |
Fn3-34 |
45 | rs1223437077 |
0.1469 | None | 0.024 | N | 0.348 | 0.163 | 0.269111216191 | gnomAD-4.0.0 | 6.57497E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47063E-05 | 0 | 0 |
| R/S | 20215 |
Fn3-34 |
45 | rs1248408963 |
0.2749 | 0.1 | 0.012 | N | 0.369 | 0.135 | 0.165133752707 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.71E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/S | 20215 |
Fn3-34 |
45 | rs1248408963 |
0.2749 | 0.1 | 0.012 | N | 0.369 | 0.135 | 0.165133752707 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 2.62226E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.79386E-04 |
| R/S | 20215 |
Fn3-34 |
45 | rs1248408963 |
0.2749 | 0.1 | 0.012 | N | 0.369 | 0.135 | 0.165133752707 | gnomAD-4.0.0 | 1.15371E-05 | None | None | None | None | N | None | 0 | 1.18725E-04 | None | 0 | 0 | None | 0 | 0 | 2.39428E-06 | 0 | 2.84576E-05 |
| T/P | 20314 |
Fn3-35 |
44 | None | 0.1761 | None | 0.891 | N | 0.327 | 0.208 | 0.270447802918 | gnomAD-4.0.0 | 1.37456E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80706E-06 | 0 | 0 |
| G/V | 20414 |
Fn3-36 |
44 | None | 0.3645 | None | 0.864 | N | 0.636 | 0.226 | 0.484400871567 | gnomAD-4.0.0 | 1.36894E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16012E-05 | 1.65706E-05 |
| I/T | 21107 |
Fn3-41 |
44 | None | 0.0775 | None | None | N | 0.192 | 0.071 | 0.101711395817 | gnomAD-4.0.0 | 6.8456E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87322E-05 | 0 | 0 | 0 | 0 |
| D/H | 21309 |
Fn3-42 |
44 | None | 0.3758 | None | 0.931 | N | 0.363 | 0.297 | 0.335910606209 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/C | 21603 |
Fn3-44 |
45 | None | 0.1474 | None | 0.999 | N | 0.449 | 0.392 | 0.490631539035 | gnomAD-4.0.0 | 1.59195E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| N/K | 21702 |
Fn3-45 |
44 | rs753302897 |
0.9269 | 0.496 | 1.0 | N | 0.553 | 0.348 | 0.218845423259 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| N/K | 21702 |
Fn3-45 |
44 | rs753302897 |
0.9269 | 0.496 | 1.0 | N | 0.553 | 0.348 | 0.218845423259 | gnomAD-4.0.0 | 1.5923E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43303E-05 | 0 |
| P/S | 21800 |
Fn3-46 |
44 | rs760650311 |
0.2255 | None | 0.322 | N | 0.36 | 0.223 | 0.143124449307 | gnomAD-4.0.0 | 2.74218E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60198E-06 | 0 | 0 |
| P/T | 21800 |
Fn3-46 |
44 | rs760650311 |
0.1977 | -0.363 | 0.885 | N | 0.454 | 0.268 | 0.307332253619 | gnomAD-2.1.1 | 8.21E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.82E-05 | 0 |
| P/T | 21800 |
Fn3-46 |
44 | rs760650311 |
0.1977 | -0.363 | 0.885 | N | 0.454 | 0.268 | 0.307332253619 | gnomAD-4.0.0 | 2.74218E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60198E-06 | 0 | 0 |
| Q/H | 22098 |
Fn3-48 |
44 | None | 0.1647 | None | None | N | 0.207 | 0.122 | 0.12205267543 | gnomAD-4.0.0 | 1.59231E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86025E-06 | 0 | 0 |
| E/A | 22397 |
Fn3-50 |
44 | None | 0.2416 | None | 0.999 | N | 0.571 | 0.418 | 0.373897652646 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/G | 22397 |
Fn3-50 |
44 | None | 0.211 | None | 1.0 | N | 0.587 | 0.395 | 0.360565625551 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| E/K | 22397 |
Fn3-50 |
44 | rs1163846592 |
0.3426 | None | 0.999 | N | 0.584 | 0.411 | 0.350524144436 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| E/K | 22397 |
Fn3-50 |
44 | rs1163846592 |
0.3426 | None | 0.999 | N | 0.584 | 0.411 | 0.350524144436 | gnomAD-4.0.0 | 6.81847E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32597E-06 | 0 | 0 |
| P/L | 22884 |
Fn3-54 |
44 | rs2046764979 |
0.2778 | None | 0.942 | N | 0.439 | 0.298 | 0.521917627825 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 22884 |
Fn3-54 |
44 | rs2046764979 |
0.2778 | None | 0.942 | N | 0.439 | 0.298 | 0.521917627825 | gnomAD-4.0.0 | 6.57774E-06 | None | None | None | None | N | None | 0 | 6.55308E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 23182 |
Fn3-56 |
44 | None | 0.2889 | None | 0.822 | N | 0.433 | 0.219 | 0.270447802918 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| K/Q | 23182 |
Fn3-56 |
44 | rs1383372565 |
0.1552 | 0.011 | 0.942 | N | 0.391 | 0.239 | 0.260249123532 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.1489E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 23182 |
Fn3-56 |
44 | rs1383372565 |
0.1552 | 0.011 | 0.942 | N | 0.391 | 0.239 | 0.260249123532 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 23182 |
Fn3-56 |
44 | rs1383372565 |
0.1552 | 0.011 | 0.942 | N | 0.391 | 0.239 | 0.260249123532 | gnomAD-4.0.0 | 6.57748E-06 | None | None | None | None | N | None | 2.41371E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 23182 |
Fn3-56 |
44 | rs773432437 |
0.0867 | 0.1 | 0.014 | N | 0.315 | 0.057 | 0.243972157842 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 1.65563E-04 |
| K/R | 23182 |
Fn3-56 |
44 | rs773432437 |
0.0867 | 0.1 | 0.014 | N | 0.315 | 0.057 | 0.243972157842 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 23182 |
Fn3-56 |
44 | rs773432437 |
0.0867 | 0.1 | 0.014 | N | 0.315 | 0.057 | 0.243972157842 | gnomAD-4.0.0 | 2.35522E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62794E-05 | 0 | 1.12093E-04 |
| G/R | 23283 |
Fn3-57 |
44 | None | 0.3318 | None | 1.0 | N | 0.709 | 0.431 | 0.545045102275 | gnomAD-4.0.0 | 6.89601E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.03215E-07 | 0 | 0 |
| G/D | 23575 |
Fn3-59 |
44 | rs754974293 |
0.1765 | -0.435 | 0.344 | N | 0.415 | 0.182 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| G/D | 23575 |
Fn3-59 |
44 | rs754974293 |
0.1765 | -0.435 | 0.344 | N | 0.415 | 0.182 | None | gnomAD-4.0.0 | 1.02644E-05 | None | None | None | None | N | None | 0 | 2.23634E-05 | None | 0 | 0 | None | 0 | 0 | 1.16941E-05 | 0 | 1.65678E-05 |
| G/R | 23575 |
Fn3-59 |
44 | None | 0.6608 | None | 1.0 | N | 0.693 | 0.363 | 0.502568190621 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85914E-06 | 0 | 0 |
| G/V | 23575 |
Fn3-59 |
44 | rs754974293 |
0.4197 | -0.199 | 1.0 | N | 0.718 | 0.321 | 0.497806138765 | gnomAD-4.0.0 | 6.84293E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15945E-05 | 0 |
| D/E | 23770 |
Fn3-60 |
45 | rs1320217778 |
0.2104 | 0.107 | 0.625 | N | 0.356 | 0.102 | 0.250579442822 | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| D/E | 23770 |
Fn3-60 |
45 | rs1320217778 |
0.2104 | 0.107 | 0.625 | N | 0.356 | 0.102 | 0.250579442822 | gnomAD-4.0.0 | 3.18681E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72289E-06 | 0 | 0 |
| D/N | 23770 |
Fn3-60 |
45 | rs747260758 |
0.0924 | 0.539 | 0.012 | N | 0.246 | 0.093 | 0.180583059064 | gnomAD-2.1.1 | 5.68E-05 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 4.26425E-04 | None | 0 | 0 | 0 |
| D/N | 23770 |
Fn3-60 |
45 | rs747260758 |
0.0924 | 0.539 | 0.012 | N | 0.246 | 0.093 | 0.180583059064 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| D/N | 23770 |
Fn3-60 |
45 | rs747260758 |
0.0924 | 0.539 | 0.012 | N | 0.246 | 0.093 | 0.180583059064 | gnomAD-4.0.0 | 3.34813E-05 | None | None | None | None | N | None | 0 | 6.67067E-05 | None | 0 | 0 | None | 0 | 0 | 2.54383E-06 | 4.94516E-04 | 3.20349E-05 |
| D/Y | 23770 |
Fn3-60 |
45 | None | 0.3692 | None | 0.989 | D | 0.366 | 0.257 | 0.5711029235 | gnomAD-4.0.0 | 6.8463E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16047E-05 | 0 |
| N/K | 23869 |
Fn3-61 |
44 | rs1709390965 |
0.6844 | None | 0.942 | N | 0.46 | 0.292 | 0.165133752707 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| N/K | 23869 |
Fn3-61 |
44 | rs1709390965 |
0.6844 | None | 0.942 | N | 0.46 | 0.292 | 0.165133752707 | gnomAD-4.0.0 | 3.09901E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23865E-06 | 0 | 0 |
| A/S | 24265 |
Fn3-64 |
44 | None | 0.0852 | None | 0.001 | N | 0.207 | 0.08 | 0.0884992946249 | gnomAD-4.0.0 | 1.787E-06 | None | None | None | None | N | None | 0 | 0 | None | 6.00673E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 24366 |
Fn3-65 |
44 | rs1708815210 |
0.094 | None | 0.505 | N | 0.427 | 0.226 | 0.241078983079 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 24366 |
Fn3-65 |
44 | rs1708815210 |
0.094 | None | 0.505 | N | 0.427 | 0.226 | 0.241078983079 | gnomAD-4.0.0 | 6.57523E-06 | None | None | None | None | N | None | 2.41336E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/V | 24366 |
Fn3-65 |
44 | rs1708814132 |
0.1845 | None | 0.879 | N | 0.435 | 0.317 | 0.425148423609 | gnomAD-4.0.0 | 1.59269E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8602E-06 | 0 | 0 |
| T/R | 24562 |
Fn3-66 |
44 | None | 0.7482 | None | 0.993 | N | 0.429 | 0.399 | 0.401185642668 | gnomAD-4.0.0 | 1.36961E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.32024E-05 | 0 |
| S/A | 24852 |
Fn3-68 |
45 | None | 0.0997 | None | 0.773 | N | 0.437 | 0.196 | 0.214338557667 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/Y | 24852 |
Fn3-68 |
45 | rs375466935 |
0.4678 | -0.678 | 0.994 | N | 0.513 | 0.462 | None | gnomAD-2.1.1 | 6.37E-05 | None | None | None | None | N | None | 2.29463E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/Y | 24852 |
Fn3-68 |
45 | rs375466935 |
0.4678 | -0.678 | 0.994 | N | 0.513 | 0.462 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/Y | 24852 |
Fn3-68 |
45 | rs375466935 |
0.4678 | -0.678 | 0.994 | N | 0.513 | 0.462 | None | gnomAD-4.0.0 | 3.8464E-06 | None | None | None | None | N | None | 3.38478E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39425E-06 | 0 | 0 |
| N/S | 24951 |
Fn3-69 |
44 | None | 0.1654 | None | 0.919 | N | 0.521 | 0.286 | 0.186928172975 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| P/S | 25049 |
Fn3-70 |
44 | rs1268559382 |
0.3851 | None | 0.616 | N | 0.413 | 0.208 | 0.1749357433 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 25049 |
Fn3-70 |
44 | rs1268559382 |
0.3851 | None | 0.616 | N | 0.413 | 0.208 | 0.1749357433 | gnomAD-4.0.0 | 6.57938E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47115E-05 | 0 | 0 |
| S/G | 25248 |
Fn3-71 |
45 | None | 0.3715 | None | 0.892 | N | 0.337 | 0.204 | 0.222439326576 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| S/N | 25248 |
Fn3-71 |
45 | rs1192508710 |
0.7245 | -0.092 | 0.892 | N | 0.361 | 0.207 | 0.229264304666 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| S/N | 25248 |
Fn3-71 |
45 | rs1192508710 |
0.7245 | -0.092 | 0.892 | N | 0.361 | 0.207 | 0.229264304666 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 25248 |
Fn3-71 |
45 | rs1192508710 |
0.7245 | -0.092 | 0.892 | N | 0.361 | 0.207 | 0.229264304666 | gnomAD-4.0.0 | 6.57566E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47111E-05 | 0 | 0 |
| E/D | 25347 |
Fn3-72 |
44 | rs1310471153 |
0.1172 | 0.076 | 0.001 | N | 0.228 | 0.063 | 0.0611884634855 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| E/D | 25347 |
Fn3-72 |
44 | rs1310471153 |
0.1172 | 0.076 | 0.001 | N | 0.228 | 0.063 | 0.0611884634855 | gnomAD-4.0.0 | 8.21205E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.39134E-04 | 0 |
| S/N | 25448 |
Fn3-73 |
44 | rs3813243 |
0.1087 | 0.036 | 0.684 | N | 0.297 | 0.154 | None | gnomAD-2.1.1 | 4.17349E-02 | None | None | None | None | N | None | 7.09147E-02 | 3.15879E-02 | None | 4.23204E-02 | 1.79369E-01 | None | 4.97351E-02 | None | 1.95338E-02 | 2.06055E-02 | 3.87858E-02 |
| S/N | 25448 |
Fn3-73 |
44 | rs3813243 |
0.1087 | 0.036 | 0.684 | N | 0.297 | 0.154 | None | gnomAD-3.1.2 | 4.25921E-02 | None | None | None | None | N | None | 7.06007E-02 | 3.91179E-02 | 8.77193E-03 | 4.23631E-02 | 1.67184E-01 | None | 1.92018E-02 | 5.6962E-02 | 2.01548E-02 | 4.77972E-02 | 5.55024E-02 |
| S/N | 25448 |
Fn3-73 |
44 | rs3813243 |
0.1087 | 0.036 | 0.684 | N | 0.297 | 0.154 | None | 1000 genomes | 7.92732E-02 | None | None | None | None | N | None | 8.55E-02 | 4.18E-02 | None | None | 1.736E-01 | 3.28E-02 | None | None | None | 4.81E-02 | None |
| S/N | 25448 |
Fn3-73 |
44 | rs3813243 |
0.1087 | 0.036 | 0.684 | N | 0.297 | 0.154 | None | gnomAD-4.0.0 | 3.04797E-02 | None | None | None | None | N | None | 7.07294E-02 | 3.47375E-02 | None | 4.28243E-02 | 1.79488E-01 | None | 1.80585E-02 | 9.45455E-02 | 2.02603E-02 | 4.91223E-02 | 3.79935E-02 |
| S/R | 25448 |
Fn3-73 |
44 | rs763099701 |
0.3992 | 0.096 | 0.939 | N | 0.347 | 0.258 | 0.247322355667 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| S/R | 25448 |
Fn3-73 |
44 | rs763099701 |
0.3992 | 0.096 | 0.939 | N | 0.347 | 0.258 | 0.247322355667 | gnomAD-4.0.0 | 2.73757E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79916E-06 | 2.31932E-05 | 0 |
| N/D | 26033 |
Fn3-77 |
44 | rs1343439092 |
0.6689 | 0.412 | 0.958 | N | 0.481 | 0.333 | 0.180583059064 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 6.50195E-04 | None | 0 | None | 0 | 0 | 0 |
| N/D | 26033 |
Fn3-77 |
44 | rs1343439092 |
0.6689 | 0.412 | 0.958 | N | 0.481 | 0.333 | 0.180583059064 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.93424E-04 | None | 0 | 0 | 0 | 0 | 0 |
| N/D | 26033 |
Fn3-77 |
44 | rs1343439092 |
0.6689 | 0.412 | 0.958 | N | 0.481 | 0.333 | 0.180583059064 | gnomAD-4.0.0 | 6.57471E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.93424E-04 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 26131 |
Fn3-78 |
44 | None | 0.4983 | None | 1.0 | N | 0.678 | 0.518 | 0.45553875121 | gnomAD-4.0.0 | 1.59355E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43328E-05 | 0 |
| P/S | 26131 |
Fn3-78 |
44 | rs764676279 |
0.5629 | -0.334 | 1.0 | N | 0.577 | 0.413 | 0.231231049324 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| P/S | 26131 |
Fn3-78 |
44 | rs764676279 |
0.5629 | -0.334 | 1.0 | N | 0.577 | 0.413 | 0.231231049324 | gnomAD-4.0.0 | 6.37448E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.14553E-05 | 0 | 0 |
| S/G | 26330 |
Fn3-79 |
45 | rs1188453832 |
0.6073 | -0.311 | 0.892 | N | 0.325 | 0.26 | 0.203808441222 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| S/G | 26330 |
Fn3-79 |
45 | rs1188453832 |
0.6073 | -0.311 | 0.892 | N | 0.325 | 0.26 | 0.203808441222 | gnomAD-4.0.0 | 4.10594E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.7975E-05 | 1.65695E-05 |
| S/N | 26330 |
Fn3-79 |
45 | rs1427996263 |
0.8939 | 0.097 | 0.892 | N | 0.344 | 0.199 | 0.173771789658 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.57E-05 | 0 |
| S/N | 26330 |
Fn3-79 |
45 | rs1427996263 |
0.8939 | 0.097 | 0.892 | N | 0.344 | 0.199 | 0.173771789658 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 26330 |
Fn3-79 |
45 | rs1427996263 |
0.8939 | 0.097 | 0.892 | N | 0.344 | 0.199 | 0.173771789658 | gnomAD-4.0.0 | 5.5783E-06 | None | None | None | None | N | None | 1.33565E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08638E-06 | 2.19597E-05 | 0 |
| S/N | 26429 |
Fn3-80 |
44 | None | 0.1284 | None | 0.491 | N | 0.24 | 0.092 | 0.16115917748 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 1.26695E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 26429 |
Fn3-80 |
44 | None | 0.6228 | None | 0.491 | N | 0.278 | 0.174 | 0.216624796971 | gnomAD-4.0.0 | 1.59205E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43283E-05 | 0 |
| D/V | 26530 |
Fn3-81 |
44 | None | 0.1295 | None | 0.983 | N | 0.591 | 0.419 | 0.36076525451 | gnomAD-4.0.0 | 1.59226E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85878E-06 | 0 | 0 |
| T/A | 26726 |
Fn3-82 |
44 | rs1258866379 |
0.1688 | -0.336 | 0.139 | N | 0.314 | 0.244 | 0.204665344411 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 26726 |
Fn3-82 |
44 | rs1258866379 |
0.1688 | -0.336 | 0.139 | N | 0.314 | 0.244 | 0.204665344411 | gnomAD-4.0.0 | 1.36856E-06 | None | None | None | None | N | None | 2.989E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99556E-07 | 0 | 0 |
| T/I | 26726 |
Fn3-82 |
44 | None | 0.6268 | None | 0.943 | N | 0.365 | 0.432 | 0.39694197178 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/P | 26726 |
Fn3-82 |
44 | None | 0.4647 | None | 0.002 | N | 0.266 | 0.319 | 0.269558022972 | gnomAD-4.0.0 | 6.84279E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99556E-07 | 0 | 0 |
| T/I | 27016 |
Fn3-84 |
45 | None | 0.4506 | None | 0.983 | N | 0.417 | 0.325 | 0.365509141856 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/N | 27016 |
Fn3-84 |
45 | rs745404390 |
0.1662 | 0.187 | 0.967 | N | 0.315 | 0.208 | 0.289098819767 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 27213 |
Fn3-86 |
44 | None | 0.4526 | None | 0.976 | N | 0.643 | 0.452 | 0.568358697712 | gnomAD-4.0.0 | 1.59542E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86457E-06 | 0 | 0 |
| P/S | 27213 |
Fn3-86 |
44 | rs375058735 |
0.5189 | None | 0.976 | N | 0.526 | 0.31 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 27213 |
Fn3-86 |
44 | rs375058735 |
0.5189 | None | 0.976 | N | 0.526 | 0.31 | None | gnomAD-4.0.0 | 6.57298E-06 | None | None | None | None | N | None | 2.41313E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 27213 |
Fn3-86 |
44 | rs375058735 |
0.3754 | -0.277 | 0.988 | N | 0.557 | 0.406 | None | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.09E-06 | 0 |
| E/A | 27512 |
Fn3-88 |
44 | None | 0.1402 | None | 0.001 | N | 0.265 | 0.128 | 0.246215685461 | gnomAD-4.0.0 | 1.59126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| E/K | 27512 |
Fn3-88 |
44 | None | 0.2645 | None | 0.175 | N | 0.309 | 0.166 | 0.249502417897 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/S | 27613 |
Fn3-89 |
44 | None | 0.0716 | None | None | N | 0.151 | 0.089 | 0.0401082797425 | gnomAD-4.0.0 | 6.15833E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09564E-06 | 0 | 0 |
| A/V | 27613 |
Fn3-89 |
44 | rs751779815 |
0.0862 | -0.005 | 0.062 | N | 0.246 | 0.082 | 0.244539031024 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| A/V | 27613 |
Fn3-89 |
44 | rs751779815 |
0.0862 | -0.005 | 0.062 | N | 0.246 | 0.082 | 0.244539031024 | gnomAD-4.0.0 | 1.59156E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| T/A | 27809 |
Fn3-90 |
44 | None | 0.1209 | None | 0.017 | N | 0.303 | 0.161 | 0.17948927462 | gnomAD-4.0.0 | 1.63701E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.91863E-06 | 0 | 0 |
| T/I | 27809 |
Fn3-90 |
44 | rs922881378 |
0.502 | -0.074 | 0.813 | N | 0.299 | 0.274 | 0.335910606209 | gnomAD-2.1.1 | 8.51E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.84E-05 | 0 |
| T/I | 27809 |
Fn3-90 |
44 | rs922881378 |
0.502 | -0.074 | 0.813 | N | 0.299 | 0.274 | 0.335910606209 | gnomAD-4.0.0 | 1.63708E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.51067E-05 | 0 |
| T/I | 28098 |
Fn3-92 |
44 | rs746141297 |
0.2765 | -0.049 | 0.989 | D | 0.55 | 0.396 | 0.453679287548 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/I | 28098 |
Fn3-92 |
44 | rs746141297 |
0.2765 | -0.049 | 0.989 | D | 0.55 | 0.396 | 0.453679287548 | gnomAD-4.0.0 | 6.84296E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99502E-07 | 0 | 0 |
| T/N | 28098 |
Fn3-92 |
44 | rs746141297 |
0.1056 | 0.247 | 0.957 | N | 0.496 | 0.252 | 0.295974979623 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/N | 28098 |
Fn3-92 |
44 | rs746141297 |
0.1056 | 0.247 | 0.957 | N | 0.496 | 0.252 | 0.295974979623 | gnomAD-4.0.0 | 1.36859E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.319E-05 | 0 |
| S/G | 28197 |
Fn3-93 |
44 | rs769905776 |
0.1068 | 0.006 | 0.656 | N | 0.337 | 0.223 | 0.124217242631 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| S/G | 28197 |
Fn3-93 |
44 | rs769905776 |
0.1068 | 0.006 | 0.656 | N | 0.337 | 0.223 | 0.124217242631 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| S/G | 28197 |
Fn3-93 |
44 | rs769905776 |
0.1068 | 0.006 | 0.656 | N | 0.337 | 0.223 | 0.124217242631 | gnomAD-4.0.0 | 3.7192E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08664E-06 | 0 | 0 |
| S/R | 28197 |
Fn3-93 |
44 | rs781670887 |
0.813 | -0.043 | 0.942 | N | 0.291 | 0.258 | 0.30212335484 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.24266E-04 | None | 0 | None | 0 | 0 | 0 |
| S/R | 28197 |
Fn3-93 |
44 | rs781670887 |
0.813 | -0.043 | 0.942 | N | 0.291 | 0.258 | 0.30212335484 | gnomAD-4.0.0 | 2.0534E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 7.57537E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 28295 |
Fn3-94 |
44 | rs1414095201 |
0.4049 | -0.02 | 1.0 | N | 0.734 | 0.545 | 0.549588557812 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14916E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 28295 |
Fn3-94 |
44 | rs1414095201 |
0.4049 | -0.02 | 1.0 | N | 0.734 | 0.545 | 0.549588557812 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 28295 |
Fn3-94 |
44 | rs1414095201 |
0.4049 | -0.02 | 1.0 | N | 0.734 | 0.545 | 0.549588557812 | gnomAD-4.0.0 | 6.57523E-06 | None | None | None | None | N | None | 2.41418E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 28494 |
Fn3-95 |
45 | rs749807293 |
0.1482 | -0.376 | 0.892 | N | 0.313 | 0.189 | 0.229924730088 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/G | 28494 |
Fn3-95 |
45 | rs749807293 |
0.1482 | -0.376 | 0.892 | N | 0.313 | 0.189 | 0.229924730088 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 9.41E-05 | 0 | 0 | 0 | 0 |
| S/G | 28494 |
Fn3-95 |
45 | rs749807293 |
0.1482 | -0.376 | 0.892 | N | 0.313 | 0.189 | 0.229924730088 | gnomAD-4.0.0 | 3.84381E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.14238E-05 | 0 | 0 | 1.34002E-05 | 0 |
| D/H | 28694 |
Fn3-97 |
44 | None | 0.1762 | None | 0.295 | N | 0.196 | 0.157 | 0.289098819767 | gnomAD-4.0.0 | 6.84256E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99454E-07 | 0 | 0 |
| D/N | 28694 |
Fn3-97 |
44 | rs796298969 |
0.0724 | None | 0.001 | N | 0.225 | 0.119 | 0.231873229951 | gnomAD-4.0.0 | 4.78979E-06 | None | None | None | None | N | None | 8.96164E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59781E-06 | 0 | 0 |
| S/G | 28888 |
Fn3-98 |
44 | rs1197285138 |
0.1172 | -0.385 | 0.822 | N | 0.291 | 0.239 | 0.134241683229 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11495E-04 | None | 0 | None | 0 | 0 | 0 |
| S/G | 28888 |
Fn3-98 |
44 | rs1197285138 |
0.1172 | -0.385 | 0.822 | N | 0.291 | 0.239 | 0.134241683229 | gnomAD-4.0.0 | 4.77444E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.54816E-05 | None | 0 | 0 | 2.85874E-06 | 0 | 0 |
| S/R | 28888 |
Fn3-98 |
44 | None | 0.9265 | None | 0.942 | N | 0.352 | 0.356 | 0.259761712551 | gnomAD-4.0.0 | 1.59152E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02407E-05 |
| S/T | 28888 |
Fn3-98 |
44 | rs1470114541 |
0.0959 | -0.238 | 0.058 | N | 0.214 | 0.052 | 0.101711395817 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| S/T | 28888 |
Fn3-98 |
44 | rs1470114541 |
0.0959 | -0.238 | 0.058 | N | 0.214 | 0.052 | 0.101711395817 | gnomAD-4.0.0 | 1.59152E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77469E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 29181 |
Fn3-100 |
45 | None | 0.0743 | None | 0.027 | N | 0.243 | 0.215 | 0.210429274316 | gnomAD-4.0.0 | 1.36832E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79886E-06 | 0 | 0 |
| S/N | 29181 |
Fn3-100 |
45 | rs768624965 |
0.1112 | 0.109 | None | N | 0.216 | 0.091 | 0.159798565429 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| S/N | 29181 |
Fn3-100 |
45 | rs768624965 |
0.1112 | 0.109 | None | N | 0.216 | 0.091 | 0.159798565429 | gnomAD-4.0.0 | 4.10499E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39659E-06 | 0 | 0 |
| S/R | 29181 |
Fn3-100 |
45 | rs776861234 |
0.5533 | 0.107 | 0.317 | N | 0.249 | 0.258 | 0.297718772494 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| S/R | 29181 |
Fn3-100 |
45 | rs776861234 |
0.5533 | 0.107 | 0.317 | N | 0.249 | 0.258 | 0.297718772494 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 29181 |
Fn3-100 |
45 | rs776861234 |
0.5533 | 0.107 | 0.317 | N | 0.249 | 0.258 | 0.297718772494 | gnomAD-4.0.0 | 1.23926E-06 | None | None | None | None | N | None | 1.33444E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47562E-07 | 0 | 0 |
| N/K | 29280 |
Fn3-101 |
44 | rs762015851 |
0.88 | 0.49 | 1.0 | N | 0.59 | 0.415 | 0.21737058555 | gnomAD-2.1.1 | 6.37E-05 | None | None | None | None | I | None | 2.29621E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/K | 29280 |
Fn3-101 |
44 | rs762015851 |
0.88 | 0.49 | 1.0 | N | 0.59 | 0.415 | 0.21737058555 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/K | 29280 |
Fn3-101 |
44 | rs762015851 |
0.88 | 0.49 | 1.0 | N | 0.59 | 0.415 | 0.21737058555 | gnomAD-4.0.0 | 1.97034E-05 | None | None | None | None | I | None | 4.81232E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4702E-05 | 0 | 0 |
| P/A | 29378 |
Fn3-102 |
44 | rs776560772 |
0.1787 | -0.118 | 0.4 | N | 0.281 | 0.165 | 0.165133752707 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| P/S | 29378 |
Fn3-102 |
44 | None | 0.2959 | None | 0.659 | N | 0.269 | 0.153 | 0.165133752707 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| S/C | 29577 |
Fn3-103 |
45 | rs1559230996 |
0.6146 | None | 1.0 | N | 0.683 | 0.596 | 0.530606565545 | gnomAD-4.0.0 | 4.77307E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88232E-05 | 0 | 0 | 0 | 6.04778E-05 |
| S/N | 29577 |
Fn3-103 |
45 | None | 0.7519 | None | 0.999 | N | 0.472 | 0.195 | 0.21279746466 | gnomAD-4.0.0 | 1.59103E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02371E-05 |
| S/R | 29577 |
Fn3-103 |
45 | None | 0.9775 | None | 1.0 | N | 0.595 | 0.496 | 0.399449838166 | gnomAD-4.0.0 | 6.84167E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51965E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 29976 |
Fn3-106 |
44 | rs772210991 |
0.3462 | 0.136 | 1.0 | N | 0.473 | 0.45 | 0.519405064759 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11782E-04 | None | 0 | None | 0 | 0 | 0 |
| T/I | 29976 |
Fn3-106 |
44 | rs772210991 |
0.3462 | 0.136 | 1.0 | N | 0.473 | 0.45 | 0.519405064759 | gnomAD-4.0.0 | 1.59396E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77685E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 29976 |
Fn3-106 |
44 | None | 0.1519 | None | 0.999 | N | 0.422 | 0.206 | 0.36355261348 | gnomAD-4.0.0 | 1.59396E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0248E-05 |
| T/P | 29976 |
Fn3-106 |
44 | None | 0.3317 | None | 1.0 | N | 0.473 | 0.459 | 0.437100570223 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| S/R | 30663 |
Fn3-111 |
45 | rs1418513895 |
0.9704 | 0.054 | 1.0 | N | 0.585 | 0.495 | 0.410734915765 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| K/Q | 30762 |
Fn3-112 |
44 | rs747890554 |
0.2184 | 0.022 | 0.99 | N | 0.541 | 0.298 | 0.253205268125 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| K/Q | 30762 |
Fn3-112 |
44 | rs747890554 |
0.2184 | 0.022 | 0.99 | N | 0.541 | 0.298 | 0.253205268125 | gnomAD-4.0.0 | 2.73672E-06 | None | None | None | None | N | None | 0 | 2.23624E-05 | None | 3.82673E-05 | 0 | None | 0 | 0 | 8.99441E-07 | 1.15934E-05 | 0 |
| K/R | 30762 |
Fn3-112 |
44 | None | 0.0963 | None | 0.904 | N | 0.477 | 0.25 | 0.365703291355 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 30864 |
Fn3-113 |
44 | rs200621611 |
0.0836 | 0.275 | 0.873 | N | 0.384 | 0.138 | None | gnomAD-2.1.1 | 8.57E-05 | None | None | None | None | N | None | 0 | 8.49E-05 | None | 0 | 1.02596E-04 | None | 9.8E-05 | None | 1.19923E-04 | 9.38E-05 | 1.40371E-04 |
| D/N | 30864 |
Fn3-113 |
44 | rs200621611 |
0.0836 | 0.275 | 0.873 | N | 0.384 | 0.138 | None | gnomAD-3.1.2 | 5.91E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 1.88573E-04 | 0 | 7.35E-05 | 0 | 0 |
| D/N | 30864 |
Fn3-113 |
44 | rs200621611 |
0.0836 | 0.275 | 0.873 | N | 0.384 | 0.138 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| D/N | 30864 |
Fn3-113 |
44 | rs200621611 |
0.0836 | 0.275 | 0.873 | N | 0.384 | 0.138 | None | gnomAD-4.0.0 | 6.87782E-05 | None | None | None | None | N | None | 2.66539E-05 | 6.666E-05 | None | 3.37815E-05 | 6.68777E-05 | None | 1.40616E-04 | 0 | 7.28914E-05 | 4.39155E-05 | 3.20092E-05 |
| S/R | 31059 |
Fn3-114 |
44 | rs769465936 |
0.9489 | -0.093 | 1.0 | N | 0.591 | 0.512 | 0.315314060047 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/T | 31059 |
Fn3-114 |
44 | rs774647356 |
0.1149 | -0.166 | 0.999 | N | 0.409 | 0.263 | 0.202086224978 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| S/T | 31059 |
Fn3-114 |
44 | rs774647356 |
0.1149 | -0.166 | 0.999 | N | 0.409 | 0.263 | 0.202086224978 | gnomAD-4.0.0 | 1.36835E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99446E-07 | 1.15931E-05 | 0 |
| G/A | 31156 |
Fn3-115 |
44 | None | 0.2662 | None | 1.0 | N | 0.504 | 0.547 | 0.340992353424 | gnomAD-4.0.0 | 6.84177E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99446E-07 | 0 | 0 |
| G/V | 31156 |
Fn3-115 |
44 | None | 0.4371 | None | 1.0 | N | 0.659 | 0.64 | 0.599340405529 | gnomAD-4.0.0 | 5.47342E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19556E-06 | 0 | 0 |
| G/A | 31352 |
Fn3-116 |
45 | rs769645414 |
0.2092 | -0.212 | 1.0 | N | 0.519 | 0.381 | 0.355865052028 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 1.65728E-04 |
| G/A | 31352 |
Fn3-116 |
45 | rs769645414 |
0.2092 | -0.212 | 1.0 | N | 0.519 | 0.381 | 0.355865052028 | gnomAD-4.0.0 | 1.36839E-06 | None | None | None | None | N | None | 0 | 2.23644E-05 | None | 0 | 0 | None | 0 | 0 | 8.99442E-07 | 0 | 0 |
| G/D | 31352 |
Fn3-116 |
45 | rs769645414 |
0.5347 | None | 1.0 | N | 0.514 | 0.46 | 0.369682402691 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/D | 31352 |
Fn3-116 |
45 | rs769645414 |
0.5347 | None | 1.0 | N | 0.514 | 0.46 | 0.369682402691 | gnomAD-4.0.0 | 1.23944E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69519E-06 | 0 | 0 |
| G/V | 31352 |
Fn3-116 |
45 | None | 0.4608 | None | 1.0 | N | 0.669 | 0.471 | 0.593515057505 | gnomAD-4.0.0 | 6.84195E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99442E-07 | 0 | 0 |
| G/A | 31552 |
Fn3-118 |
47 | None | 0.1225 | None | 0.978 | N | 0.377 | 0.303 | 0.225902525712 | gnomAD-4.0.0 | 1.5913E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| G/R | 31552 |
Fn3-118 |
47 | rs1219078324 |
0.337 | -0.234 | 0.994 | N | 0.578 | 0.395 | 0.629401724697 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/R | 31552 |
Fn3-118 |
47 | rs1219078324 |
0.337 | -0.234 | 0.994 | N | 0.578 | 0.395 | 0.629401724697 | gnomAD-4.0.0 | 3.18267E-06 | None | None | None | None | N | None | 0 | 4.57331E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 31751 |
Fn3-119 |
44 | rs372132740 |
0.5644 | -0.307 | 1.0 | N | 0.67 | 0.574 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| S/C | 31751 |
Fn3-119 |
44 | rs372132740 |
0.5644 | -0.307 | 1.0 | N | 0.67 | 0.574 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| S/C | 31751 |
Fn3-119 |
44 | rs372132740 |
0.5644 | -0.307 | 1.0 | N | 0.67 | 0.574 | None | gnomAD-4.0.0 | 3.04475E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.61474E-06 | 0 | 0 |
| S/G | 31751 |
Fn3-119 |
44 | rs372132740 |
0.3106 | -0.561 | 0.999 | N | 0.418 | 0.29 | 0.247322355667 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| S/R | 31751 |
Fn3-119 |
44 | rs753420295 |
0.9744 | -0.143 | 1.0 | N | 0.604 | 0.591 | 0.327686398923 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| S/R | 31751 |
Fn3-119 |
44 | rs753420295 |
0.9744 | -0.143 | 1.0 | N | 0.604 | 0.591 | 0.327686398923 | gnomAD-4.0.0 | 8.8948E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.07936E-05 | 0 | 1.65678E-05 |
| S/T | 31751 |
Fn3-119 |
44 | rs1223455292 |
0.2847 | -0.209 | 0.999 | N | 0.403 | 0.306 | 0.269558022972 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| A/T | 32148 |
Fn3-122 |
44 | rs1177332829 |
0.1002 | -0.273 | 0.811 | N | 0.277 | 0.11 | 0.45755974854 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 32148 |
Fn3-122 |
44 | rs1177332829 |
0.1002 | -0.273 | 0.811 | N | 0.277 | 0.11 | 0.45755974854 | gnomAD-4.0.0 | 1.36908E-06 | None | None | None | None | N | None | 2.98829E-05 | 2.23694E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 32148 |
Fn3-122 |
44 | None | 0.1957 | None | 0.896 | N | 0.251 | 0.204 | 0.562953682449 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| G/S | 32245 |
Fn3-123 |
44 | rs1559120718 |
0.1724 | None | 0.986 | N | 0.554 | 0.326 | 0.363158594168 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65563E-04 |
| G/S | 32245 |
Fn3-123 |
44 | rs1559120718 |
0.1724 | None | 0.986 | N | 0.554 | 0.326 | 0.363158594168 | gnomAD-4.0.0 | 1.59116E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02389E-05 |
| H/R | 32443 |
Fn3-124 |
45 | None | 0.3389 | None | 1.0 | N | 0.523 | 0.409 | 0.252681307341 | gnomAD-4.0.0 | 2.05276E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99502E-07 | 0 | 3.31345E-05 |
| R/G | 32542 |
Fn3-125 |
44 | rs1559104048 |
0.1617 | None | 0.071 | N | 0.357 | 0.201 | 0.144782658237 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| R/G | 32542 |
Fn3-125 |
44 | rs1559104048 |
0.1617 | None | 0.071 | N | 0.357 | 0.201 | 0.144782658237 | gnomAD-4.0.0 | 1.59198E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02627E-05 |
| R/K | 32542 |
Fn3-125 |
44 | None | 0.1275 | None | 0.122 | N | 0.267 | 0.137 | 0.186928172975 | gnomAD-4.0.0 | 6.84343E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.52118E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 32542 |
Fn3-125 |
44 | rs1449597774 |
0.2432 | None | 0.98 | N | 0.495 | 0.292 | 0.292787519742 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/T | 32542 |
Fn3-125 |
44 | rs1449597774 |
0.2432 | None | 0.98 | N | 0.495 | 0.292 | 0.292787519742 | gnomAD-4.0.0 | 4.33863E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.22995E-05 | None | 0 | 0 | 5.08638E-06 | 0 | 0 |
| D/G | 32643 |
Fn3-126 |
44 | None | 0.1218 | None | 1.0 | N | 0.551 | 0.369 | 0.204665344411 | gnomAD-4.0.0 | 1.59117E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88232E-05 | 0 | 0 | 0 | 0 |
| D/Y | 32643 |
Fn3-126 |
44 | rs188081737 |
0.3831 | 0.123 | 1.0 | N | 0.673 | 0.484 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 32643 |
Fn3-126 |
44 | rs188081737 |
0.3831 | 0.123 | 1.0 | N | 0.673 | 0.484 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 32643 |
Fn3-126 |
44 | rs188081737 |
0.3831 | 0.123 | 1.0 | N | 0.673 | 0.484 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/Y | 32643 |
Fn3-126 |
44 | rs188081737 |
0.3831 | 0.123 | 1.0 | N | 0.673 | 0.484 | None | gnomAD-4.0.0 | 5.1239E-06 | None | None | None | None | N | None | 1.68885E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.02037E-05 | 0 |
| P/R | 32839 |
Fn3-127 |
45 | None | 0.323 | None | 0.83 | N | 0.665 | 0.368 | 0.286081765059 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/T | 32839 |
Fn3-127 |
45 | rs949917519 |
0.1808 | None | 0.709 | N | 0.547 | 0.219 | 0.221734844693 | gnomAD-4.0.0 | 2.25781E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69838E-05 | 0 | 4.96952E-05 |
| S/C | 32940 |
Fn3-128 |
45 | None | 0.1718 | None | 0.997 | N | 0.566 | 0.451 | 0.465294738428 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/E | 33334 |
Fn3-130 |
45 | None | 0.2118 | None | 0.716 | N | 0.473 | 0.299 | 0.201204373187 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| K/R | 33334 |
Fn3-130 |
45 | rs1178919533 |
0.1066 | None | 0.035 | N | 0.305 | 0.115 | 0.222439326576 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 33334 |
Fn3-130 |
45 | rs1178919533 |
0.1066 | None | 0.035 | N | 0.305 | 0.115 | 0.222439326576 | gnomAD-4.0.0 | 2.5638E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78794E-06 | 0 | 0 |
| K/Q | 33435 |
Fn3-131 |
44 | rs773848816 |
0.1919 | -0.08 | 0.999 | N | 0.617 | 0.291 | 0.218112801441 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 8.53E-05 | None | 0 | 1.02575E-04 | None | 0 | None | 0 | 7.84E-06 | 0 |
| K/Q | 33435 |
Fn3-131 |
44 | rs773848816 |
0.1919 | -0.08 | 0.999 | N | 0.617 | 0.291 | 0.218112801441 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.92604E-04 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| K/Q | 33435 |
Fn3-131 |
44 | rs773848816 |
0.1919 | -0.08 | 0.999 | N | 0.617 | 0.291 | 0.218112801441 | gnomAD-4.0.0 | 1.79904E-05 | None | None | None | None | N | None | 1.33736E-05 | 5.0132E-05 | None | 0 | 4.45692E-05 | None | 0 | 0 | 1.52704E-05 | 2.19959E-05 | 4.80893E-05 |
| K/T | 33435 |
Fn3-131 |
44 | rs1311083435 |
0.2587 | None | 0.999 | N | 0.621 | 0.506 | 0.396494342077 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/T | 33435 |
Fn3-131 |
44 | rs1311083435 |
0.2587 | None | 0.999 | N | 0.621 | 0.506 | 0.396494342077 | gnomAD-4.0.0 | 6.56892E-06 | None | None | None | None | N | None | 2.41115E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 33732 |
Fn3-132 |
44 | rs1690986189 |
0.1953 | None | 0.499 | N | 0.475 | 0.213 | 0.143124449307 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| T/I | 33732 |
Fn3-132 |
44 | rs1690985152 |
0.7694 | None | 0.998 | N | 0.575 | 0.389 | 0.48418289745800003 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 33732 |
Fn3-132 |
44 | rs1690985152 |
0.7694 | None | 0.998 | N | 0.575 | 0.389 | 0.48418289745800003 | gnomAD-4.0.0 | 2.56187E-06 | None | None | None | None | N | None | 1.69096E-05 | 1.69463E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.