Structural position:
- Domain Type: Fn3
- Aligned Position: 60
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R/G | 15701 |
Fn3-1 |
45 | None | 0.8725 | None | 1.0 | N | 0.53 | 0.38 | 0.377799810692 | gnomAD-4.0.0 | 1.59365E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| K/R | 15903 |
Fn3-3 |
45 | rs753276843 |
0.0899 | 0.099 | 0.891 | N | 0.254 | 0.09 | 0.246215685461 | gnomAD-2.1.1 | 1.85E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.03E-05 | 0 |
| K/R | 15903 |
Fn3-3 |
45 | rs753276843 |
0.0899 | 0.099 | 0.891 | N | 0.254 | 0.09 | 0.246215685461 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 15903 |
Fn3-3 |
45 | rs753276843 |
0.0899 | 0.099 | 0.891 | N | 0.254 | 0.09 | 0.246215685461 | gnomAD-4.0.0 | 1.00779E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.28183E-05 | 0 | 1.62676E-05 |
| R/Q | 16099 |
Fn3-4 |
45 | rs376747673 |
0.3944 | -0.14 | 1.0 | N | 0.645 | 0.3 | None | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | N | None | 1.24492E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.73E-05 | 0 |
| R/Q | 16099 |
Fn3-4 |
45 | rs376747673 |
0.3944 | -0.14 | 1.0 | N | 0.645 | 0.3 | None | gnomAD-3.1.2 | 4.61E-05 | None | None | None | None | N | None | 7.25E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 0 | 0 |
| R/Q | 16099 |
Fn3-4 |
45 | rs376747673 |
0.3944 | -0.14 | 1.0 | N | 0.645 | 0.3 | None | gnomAD-4.0.0 | 6.82414E-05 | None | None | None | None | N | None | 8.0274E-05 | 0 | None | 3.38593E-05 | 0 | None | 0 | 0 | 7.97467E-05 | 2.19814E-05 | 1.12266E-04 |
| R/W | 16099 |
Fn3-4 |
45 | rs765526529 |
0.6568 | -0.576 | 1.0 | D | 0.743 | 0.419 | 0.353125101423 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| R/W | 16099 |
Fn3-4 |
45 | rs765526529 |
0.6568 | -0.576 | 1.0 | D | 0.743 | 0.419 | 0.353125101423 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/W | 16099 |
Fn3-4 |
45 | rs765526529 |
0.6568 | -0.576 | 1.0 | D | 0.743 | 0.419 | 0.353125101423 | gnomAD-4.0.0 | 1.61313E-05 | None | None | None | None | N | None | 1.33894E-05 | 1.67051E-05 | None | 0 | 0 | None | 0 | 3.29815E-04 | 1.61196E-05 | 3.29801E-05 | 0 |
| S/P | 16199 |
Fn3-5 |
45 | rs752629624 |
0.8153 | -0.474 | 0.891 | N | 0.335 | 0.203 | None | gnomAD-2.1.1 | 5.37E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.17439E-04 | 0 |
| S/P | 16199 |
Fn3-5 |
45 | rs752629624 |
0.8153 | -0.474 | 0.891 | N | 0.335 | 0.203 | None | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47236E-04 | 0 | 0 |
| S/P | 16199 |
Fn3-5 |
45 | rs752629624 |
0.8153 | -0.474 | 0.891 | N | 0.335 | 0.203 | None | gnomAD-4.0.0 | 1.09157E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4334E-04 | 0 | 1.12205E-04 |
| S/Y | 16199 |
Fn3-5 |
45 | None | 0.3314 | None | 0.989 | D | 0.369 | 0.353 | 0.564541561611 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 3.66327E-05 |
| T/K | 16494 |
Fn3-7 |
45 | rs1576450617 |
0.335 | None | 0.062 | N | 0.279 | 0.081 | 0.225215365344 | gnomAD-4.0.0 | 1.59374E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86356E-06 | 0 | 0 |
| T/I | 16595 |
Fn3-8 |
45 | rs1235386202 |
0.4501 | None | 0.999 | D | 0.555 | 0.42 | 0.407082143382 | gnomAD-4.0.0 | 1.24018E-06 | None | None | None | None | N | None | 1.33454E-05 | 1.669E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 16595 |
Fn3-8 |
45 | rs1235386202 |
0.3136 | -0.264 | 0.999 | N | 0.54 | 0.438 | 0.518092603711 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| T/R | 16595 |
Fn3-8 |
45 | rs1235386202 |
0.3136 | -0.264 | 0.999 | N | 0.54 | 0.438 | 0.518092603711 | gnomAD-4.0.0 | 3.10068E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69596E-06 | 3.2946E-05 | 0 |
| R/Q | 16695 |
Fn3-9 |
45 | rs794729451 |
0.594 | 0.167 | 1.0 | N | 0.647 | 0.283 | None | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.67224E-04 |
| R/Q | 16695 |
Fn3-9 |
45 | rs794729451 |
0.594 | 0.167 | 1.0 | N | 0.647 | 0.283 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 2.07383E-04 | 0 |
| R/Q | 16695 |
Fn3-9 |
45 | rs794729451 |
0.594 | 0.167 | 1.0 | N | 0.647 | 0.283 | None | gnomAD-4.0.0 | 1.05435E-05 | None | None | None | None | N | None | 2.6738E-05 | 0 | None | 0 | 2.24366E-05 | None | 1.56436E-05 | 0 | 8.48028E-06 | 2.19674E-05 | 1.60318E-05 |
| T/A | 16896 |
Fn3-11 |
45 | None | 0.1717 | None | 0.999 | N | 0.381 | 0.215 | 0.173771789658 | gnomAD-4.0.0 | 2.05348E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69933E-06 | 0 | 0 |
| R/T | 17091 |
Fn3-12 |
45 | None | 0.9668 | None | 1.0 | N | 0.573 | 0.438 | 0.370789594751 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 17191 |
Fn3-13 |
45 | None | 0.2315 | None | 0.012 | N | 0.197 | 0.137 | 0.211220785272 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 1.26695E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 17413 |
Fn3-14 |
45 | rs749984408 |
0.5747 | -0.511 | 0.999 | N | 0.577 | 0.219 | 0.209622950755 | gnomAD-4.0.0 | 3.18786E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88608E-05 | 0 | 2.86226E-06 | 0 | 0 |
| T/I | 17613 |
Fn3-16 |
45 | None | 0.2853 | None | 0.885 | N | 0.313 | 0.328 | 0.303453137403 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/S | 17613 |
Fn3-16 |
45 | None | 0.1169 | None | 0.17 | N | 0.3 | 0.088 | 0.0762999501168 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| M/I | 17808 |
Fn3-17 |
45 | rs1018984134 |
0.8019 | None | 0.454 | N | 0.303 | 0.226 | 0.436025050644 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.78927E-04 |
| M/I | 17808 |
Fn3-17 |
45 | rs1018984134 |
0.8019 | None | 0.454 | N | 0.303 | 0.226 | 0.436025050644 | gnomAD-4.0.0 | 3.0998E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39189E-06 | 0 | 1.60174E-05 |
| K/R | 17906 |
Fn3-18 |
45 | rs727503606 |
0.0898 | -0.178 | None | N | 0.139 | 0.064 | None | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| K/R | 17906 |
Fn3-18 |
45 | rs727503606 |
0.0898 | -0.178 | None | N | 0.139 | 0.064 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| K/R | 17906 |
Fn3-18 |
45 | rs727503606 |
0.0898 | -0.178 | None | N | 0.139 | 0.064 | None | gnomAD-4.0.0 | 8.68364E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18759E-05 | 0 | 0 |
| R/G | 18109 |
Fn3-19 |
45 | None | 0.3777 | None | 0.005 | N | 0.163 | 0.211 | 0.350746614512 | gnomAD-4.0.0 | 6.8482E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16163E-05 | 0 |
| R/K | 18109 |
Fn3-19 |
45 | rs1422300331 |
0.1095 | 0.082 | 0.005 | N | 0.14 | 0.084 | 0.162503812791 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| R/K | 18109 |
Fn3-19 |
45 | rs1422300331 |
0.1095 | 0.082 | 0.005 | N | 0.14 | 0.084 | 0.162503812791 | gnomAD-4.0.0 | 1.59496E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03141E-05 |
| S/I | 18210 |
Fn3-20 |
45 | None | 0.2441 | None | 0.055 | N | 0.363 | 0.196 | 0.436348499334 | gnomAD-4.0.0 | 6.84561E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99896E-07 | 0 | 0 |
| S/T | 18210 |
Fn3-20 |
45 | None | 0.1274 | None | None | N | 0.117 | 0.193 | 0.193865811164 | gnomAD-4.0.0 | 6.84561E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99896E-07 | 0 | 0 |
| T/I | 18316 |
Fn3-21 |
45 | None | 0.2876 | None | 0.317 | N | 0.293 | 0.068 | 0.132336055621 | gnomAD-4.0.0 | 1.59429E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86298E-06 | 0 | 0 |
| T/S | 18316 |
Fn3-21 |
45 | rs758527900 |
0.0793 | -0.297 | None | N | 0.082 | 0.072 | 0.0401082797425 | gnomAD-2.1.1 | 7.46968E-04 | None | None | None | None | N | None | 0 | 5.32782E-03 | None | 0 | 0 | None | 0 | None | 0 | 0 | 3.34001E-04 |
| T/S | 18316 |
Fn3-21 |
45 | rs758527900 |
0.0793 | -0.297 | None | N | 0.082 | 0.072 | 0.0401082797425 | gnomAD-3.1.2 | 4.61E-05 | None | None | None | None | N | None | 0 | 4.59318E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 18316 |
Fn3-21 |
45 | rs758527900 |
0.0793 | -0.297 | None | N | 0.082 | 0.072 | 0.0401082797425 | gnomAD-4.0.0 | 2.70801E-04 | None | None | None | None | N | None | 0 | 3.49888E-03 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.42507E-04 |
| G/A | 18523 |
Fn3-22 |
45 | None | 0.2084 | None | 0.998 | N | 0.485 | 0.331 | 0.348101942276 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/R | 18523 |
Fn3-22 |
45 | rs1357033884 |
0.5183 | -0.267 | 0.999 | N | 0.73 | 0.444 | 0.58934274002 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| R/G | 18829 |
Fn3-24 |
46 | None | 0.7571 | None | 0.822 | N | 0.348 | 0.249 | 0.393159880135 | gnomAD-4.0.0 | 6.85993E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.17195E-05 | 0 |
| R/K | 18829 |
Fn3-24 |
46 | rs1056753359 |
0.2553 | None | 0.656 | N | 0.393 | 0.176 | 0.290590437066 | gnomAD-4.0.0 | 1.60175E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78645E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 19228 |
Fn3-27 |
46 | rs757820671 |
0.1986 | -0.35 | 0.992 | N | 0.597 | 0.458 | None | gnomAD-2.1.1 | 4.05E-05 | None | None | None | None | N | None | 1.70416E-04 | 1.15902E-04 | None | 0 | 0 | None | 0 | None | 0 | 2.42E-05 | 0 |
| R/C | 19228 |
Fn3-27 |
46 | rs757820671 |
0.1986 | -0.35 | 0.992 | N | 0.597 | 0.458 | None | gnomAD-3.1.2 | 4.61E-05 | None | None | None | None | N | None | 1.45145E-04 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 19228 |
Fn3-27 |
46 | rs757820671 |
0.1986 | -0.35 | 0.992 | N | 0.597 | 0.458 | None | gnomAD-4.0.0 | 1.67895E-05 | None | None | None | None | N | None | 1.73899E-04 | 5.05493E-05 | None | 0 | 0 | None | 0 | 0 | 6.79479E-06 | 1.11351E-05 | 3.21017E-05 |
| R/H | 19228 |
Fn3-27 |
46 | rs114711705 |
0.1055 | -1.232 | 0.005 | N | 0.195 | 0.107 | None | gnomAD-2.1.1 | 6.82103E-04 | None | None | None | None | N | None | 7.37866E-03 | 2.32194E-04 | None | 0 | 5.34E-05 | None | 0 | None | 0 | 0 | 4.3054E-04 |
| R/H | 19228 |
Fn3-27 |
46 | rs114711705 |
0.1055 | -1.232 | 0.005 | N | 0.195 | 0.107 | None | gnomAD-3.1.2 | 1.96786E-03 | None | None | None | None | N | None | 7.05484E-03 | 1.31182E-04 | 0 | 0 | 1.9425E-04 | None | 0 | 0 | 0 | 0 | 1.91205E-03 |
| R/H | 19228 |
Fn3-27 |
46 | rs114711705 |
0.1055 | -1.232 | 0.005 | N | 0.195 | 0.107 | None | 1000 genomes | 2.59585E-03 | None | None | None | None | N | None | 9.8E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/H | 19228 |
Fn3-27 |
46 | rs114711705 |
0.1055 | -1.232 | 0.005 | N | 0.195 | 0.107 | None | gnomAD-4.0.0 | 3.97341E-04 | None | None | None | None | N | None | 7.6999E-03 | 3.03306E-04 | None | 0 | 2.25063E-05 | None | 1.56966E-05 | 0 | 6.79519E-06 | 1.11421E-05 | 5.29593E-04 |
| S/F | 19622 |
Fn3-30 |
44 | None | 0.6421 | None | 0.896 | N | 0.364 | 0.519 | 0.612105117874 | gnomAD-4.0.0 | 6.84368E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15964E-05 | 0 |
| S/Y | 19622 |
Fn3-30 |
44 | rs144576333 |
0.5761 | -0.761 | 0.963 | N | 0.35 | 0.455 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| S/Y | 19622 |
Fn3-30 |
44 | rs144576333 |
0.5761 | -0.761 | 0.963 | N | 0.35 | 0.455 | None | gnomAD-4.0.0 | 6.84368E-07 | None | None | None | None | N | None | 2.99007E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 19724 |
Fn3-31 |
45 | rs1373178934 |
0.1028 | None | 0.005 | N | 0.151 | 0.139 | 0.279776271856 | gnomAD-4.0.0 | 1.3686E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79916E-06 | 0 | 0 |
| S/T | 19921 |
Fn3-32 |
45 | rs749120617 |
0.0717 | -0.343 | None | N | 0.121 | 0.124 | 0.0884992946249 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/T | 19921 |
Fn3-32 |
45 | rs749120617 |
0.0717 | -0.343 | None | N | 0.121 | 0.124 | 0.0884992946249 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 19921 |
Fn3-32 |
45 | rs749120617 |
0.0717 | -0.343 | None | N | 0.121 | 0.124 | 0.0884992946249 | gnomAD-4.0.0 | 2.4802E-06 | None | None | None | None | N | None | 4.00812E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09837E-05 | 0 |
| T/I | 20021 |
Fn3-33 |
45 | rs760706351 |
0.1539 | -0.158 | 0.012 | N | 0.356 | 0.209 | 0.246215685461 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.61458E-04 | None | 0 | None | 0 | 0 | 0 |
| T/I | 20021 |
Fn3-33 |
45 | rs760706351 |
0.1539 | -0.158 | 0.012 | N | 0.356 | 0.209 | 0.246215685461 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94175E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 20021 |
Fn3-33 |
45 | rs760706351 |
0.1539 | -0.158 | 0.012 | N | 0.356 | 0.209 | 0.246215685461 | gnomAD-4.0.0 | 4.3394E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.34126E-04 | None | 0 | 0 | 8.47785E-07 | 0 | 0 |
| T/N | 20021 |
Fn3-33 |
45 | rs760706351 |
0.0817 | -0.386 | 0.029 | N | 0.244 | 0.06 | 0.188950314367 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/N | 20021 |
Fn3-33 |
45 | rs760706351 |
0.0817 | -0.386 | 0.029 | N | 0.244 | 0.06 | 0.188950314367 | gnomAD-4.0.0 | 6.84379E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99611E-07 | 0 | 0 |
| T/S | 20021 |
Fn3-33 |
45 | rs1374902089 |
0.0785 | -0.613 | 0.005 | N | 0.261 | 0.047 | 0.0806252709748 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/S | 20021 |
Fn3-33 |
45 | rs1374902089 |
0.0785 | -0.613 | 0.005 | N | 0.261 | 0.047 | 0.0806252709748 | gnomAD-4.0.0 | 1.59217E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85968E-06 | 0 | 0 |
| T/A | 20415 |
Fn3-36 |
45 | rs1376276368 |
0.0828 | -0.327 | None | N | 0.085 | 0.106 | 0.136095386433 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| T/I | 20415 |
Fn3-36 |
45 | rs760457056 |
0.1934 | -0.085 | 0.029 | N | 0.357 | 0.179 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 8.9E-06 | 0 |
| T/I | 20415 |
Fn3-36 |
45 | rs760457056 |
0.1934 | -0.085 | 0.029 | N | 0.357 | 0.179 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 20415 |
Fn3-36 |
45 | rs760457056 |
0.1934 | -0.085 | 0.029 | N | 0.357 | 0.179 | None | gnomAD-4.0.0 | 1.05402E-05 | None | None | None | None | N | None | 1.33658E-05 | 0 | None | 0 | 2.23314E-05 | None | 0 | 0 | 9.32667E-06 | 4.39483E-05 | 0 |
| T/K | 20415 |
Fn3-36 |
45 | rs760457056 |
0.1706 | -0.391 | None | N | 0.2 | 0.075 | 0.177238962908 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/K | 20415 |
Fn3-36 |
45 | rs760457056 |
0.1706 | -0.391 | None | N | 0.2 | 0.075 | 0.177238962908 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/K | 20415 |
Fn3-36 |
45 | rs760457056 |
0.1706 | -0.391 | None | N | 0.2 | 0.075 | 0.177238962908 | gnomAD-4.0.0 | 8.06016E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01745E-05 | 0 | 1.60169E-05 |
| Q/H | 20613 |
Fn3-37 |
45 | None | 0.384 | None | 0.794 | N | 0.228 | 0.147 | 0.296329037015 | gnomAD-4.0.0 | 1.59215E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76826E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 20613 |
Fn3-37 |
45 | rs768175805 |
0.286 | -0.23 | 0.002 | N | 0.115 | 0.115 | 0.144782658237 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| Q/R | 20613 |
Fn3-37 |
45 | rs768175805 |
0.286 | -0.23 | 0.002 | N | 0.115 | 0.115 | 0.144782658237 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Q/R | 20613 |
Fn3-37 |
45 | rs768175805 |
0.286 | -0.23 | 0.002 | N | 0.115 | 0.115 | 0.144782658237 | gnomAD-4.0.0 | 8.97201E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.67588E-05 | 0 | 0 |
| R/P | 20908 |
Fn3-39 |
45 | rs377203669 |
0.9821 | 0.278 | 1.0 | N | 0.65 | 0.435 | 0.51721326083 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/P | 20908 |
Fn3-39 |
45 | rs377203669 |
0.9821 | 0.278 | 1.0 | N | 0.65 | 0.435 | 0.51721326083 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/P | 20908 |
Fn3-39 |
45 | rs377203669 |
0.9821 | 0.278 | 1.0 | N | 0.65 | 0.435 | 0.51721326083 | gnomAD-4.0.0 | 6.57834E-06 | None | None | None | None | I | None | 2.41488E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 20908 |
Fn3-39 |
45 | rs377203669 |
0.6539 | 0.081 | 1.0 | N | 0.649 | 0.434 | None | gnomAD-2.1.1 | 8.14E-05 | None | None | None | None | I | None | 6.49E-05 | 0 | None | 0 | 7.97721E-04 | None | 9.83E-05 | None | 0 | 1.8E-05 | 0 |
| R/Q | 20908 |
Fn3-39 |
45 | rs377203669 |
0.6539 | 0.081 | 1.0 | N | 0.649 | 0.434 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | I | None | 7.24E-05 | 0 | 0 | 0 | 7.77303E-04 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/Q | 20908 |
Fn3-39 |
45 | rs377203669 |
0.6539 | 0.081 | 1.0 | N | 0.649 | 0.434 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| R/Q | 20908 |
Fn3-39 |
45 | rs377203669 |
0.6539 | 0.081 | 1.0 | N | 0.649 | 0.434 | None | gnomAD-4.0.0 | 3.66159E-05 | None | None | None | None | I | None | 5.33433E-05 | 5.01253E-05 | None | 0 | 4.0404E-04 | None | 1.59424E-05 | 0 | 2.20481E-05 | 4.39425E-05 | 4.80769E-05 |
| D/A | 21113 |
Fn3-41 |
50 | rs748932912 |
0.0957 | -0.632 | 0.09 | N | 0.425 | 0.253 | 0.300784259202 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
| D/A | 21113 |
Fn3-41 |
50 | rs748932912 |
0.0957 | -0.632 | 0.09 | N | 0.425 | 0.253 | 0.300784259202 | gnomAD-4.0.0 | 6.16069E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29837E-06 | 0 | 3.31466E-05 |
| R/K | 21310 |
Fn3-42 |
45 | None | 0.2658 | None | 0.025 | N | 0.321 | 0.133 | 0.305730143919 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 21604 |
Fn3-44 |
46 | rs767011515 |
0.221 | -0.683 | 0.417 | N | 0.35 | 0.161 | 0.37262878642 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| R/G | 21604 |
Fn3-44 |
46 | rs767011515 |
0.221 | -0.683 | 0.417 | N | 0.35 | 0.161 | 0.37262878642 | gnomAD-4.0.0 | 1.36869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79925E-06 | 0 | 0 |
| R/P | 21604 |
Fn3-44 |
46 | rs188996850 |
0.808 | None | 0.836 | N | 0.456 | 0.263 | 0.393316636838 | gnomAD-4.0.0 | 1.36868E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.04236E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 21604 |
Fn3-44 |
46 | rs188996850 |
0.0906 | 0.052 | 0.005 | N | 0.227 | 0.083 | None | gnomAD-2.1.1 | 1.07279E-04 | None | None | None | None | N | None | 0 | 1.6977E-04 | None | 0 | 1.13064E-03 | None | 0 | None | 0 | 0 | 2.80978E-04 |
| R/Q | 21604 |
Fn3-44 |
46 | rs188996850 |
0.0906 | 0.052 | 0.005 | N | 0.227 | 0.083 | None | gnomAD-3.1.2 | 2.56643E-04 | None | None | None | None | N | None | 0 | 2.36158E-03 | 0 | 0 | 5.83885E-04 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 21604 |
Fn3-44 |
46 | rs188996850 |
0.0906 | 0.052 | 0.005 | N | 0.227 | 0.083 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 4.3E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/Q | 21604 |
Fn3-44 |
46 | rs188996850 |
0.0906 | 0.052 | 0.005 | N | 0.227 | 0.083 | None | gnomAD-4.0.0 | 5.95039E-05 | None | None | None | None | N | None | 2.66788E-05 | 9.83792E-04 | None | 0 | 3.79549E-04 | None | 0 | 0 | 5.08677E-06 | 0 | 1.92141E-04 |
| S/G | 21703 |
Fn3-45 |
45 | rs938258873 |
0.3236 | -0.661 | 0.999 | N | 0.422 | 0.193 | 0.202949470691 | gnomAD-2.1.1 | 6.38E-05 | None | None | None | None | N | None | 2.29568E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/G | 21703 |
Fn3-45 |
45 | rs938258873 |
0.3236 | -0.661 | 0.999 | N | 0.422 | 0.193 | 0.202949470691 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 21703 |
Fn3-45 |
45 | rs938258873 |
0.3236 | -0.661 | 0.999 | N | 0.422 | 0.193 | 0.202949470691 | gnomAD-4.0.0 | 1.31517E-05 | None | None | None | None | N | None | 4.82789E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 21703 |
Fn3-45 |
45 | None | 0.7164 | None | 0.999 | N | 0.521 | 0.328 | 0.213573922156 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/D | 21801 |
Fn3-46 |
45 | None | 0.2032 | None | 0.811 | N | 0.306 | 0.27 | 0.239305524855 | gnomAD-4.0.0 | 1.59823E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86832E-06 | 0 | 0 |
| A/S | 22099 |
Fn3-48 |
45 | rs1575927891 |
0.089 | None | 0.006 | N | 0.206 | 0.061 | 0.110078149338 | gnomAD-4.0.0 | 1.59232E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86026E-06 | 0 | 0 |
| A/V | 22099 |
Fn3-48 |
45 | rs2047904068 |
0.2223 | None | 0.193 | N | 0.323 | 0.136 | 0.371531589858 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.42E-05 | 0 | 0 | 0 | 0 |
| A/V | 22099 |
Fn3-48 |
45 | rs2047904068 |
0.2223 | None | 0.193 | N | 0.323 | 0.136 | 0.371531589858 | gnomAD-4.0.0 | 7.69221E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.42863E-05 | 0 | 0 | 0 | 0 |
| S/C | 22200 |
Fn3-49 |
45 | None | 0.1308 | None | 0.873 | N | 0.469 | 0.321 | 0.340992353424 | gnomAD-4.0.0 | 1.36939E-06 | None | None | None | None | N | None | 2.99222E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99875E-07 | 0 | 0 |
| S/F | 22200 |
Fn3-49 |
45 | rs749655019 |
0.3845 | -1.32 | 0.873 | N | 0.475 | 0.236 | 0.462111473445 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63666E-04 | None | 0 | 0 | 0 |
| S/F | 22200 |
Fn3-49 |
45 | rs749655019 |
0.3845 | -1.32 | 0.873 | N | 0.475 | 0.236 | 0.462111473445 | gnomAD-4.0.0 | 6.84693E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79975E-06 | 8.11933E-05 | 1.65815E-05 |
| R/K | 22398 |
Fn3-50 |
45 | None | 0.1858 | None | 0.997 | N | 0.389 | 0.257 | 0.352262096564 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/I | 22688 |
Fn3-52 |
46 | rs748527420 |
0.418 | 0.098 | 0.491 | N | 0.345 | 0.174 | 0.37762505005 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| N/I | 22688 |
Fn3-52 |
46 | rs748527420 |
0.418 | 0.098 | 0.491 | N | 0.345 | 0.174 | 0.37762505005 | gnomAD-4.0.0 | 6.36947E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.73148E-05 | 0 |
| N/K | 22688 |
Fn3-52 |
46 | None | 0.4215 | None | 0.166 | N | 0.175 | 0.098 | 0.143124449307 | gnomAD-4.0.0 | 1.59238E-06 | None | None | None | None | N | None | 0 | 2.2876E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 22885 |
Fn3-54 |
45 | rs376574861 |
0.1055 | -0.31 | 0.859 | N | 0.366 | 0.227 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 8.94E-06 | 0 |
| S/L | 22885 |
Fn3-54 |
45 | rs376574861 |
0.1055 | -0.31 | 0.859 | N | 0.366 | 0.227 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| S/L | 22885 |
Fn3-54 |
45 | rs376574861 |
0.1055 | -0.31 | 0.859 | N | 0.366 | 0.227 | None | gnomAD-4.0.0 | 9.91869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93444E-06 | 9.88555E-05 | 0 |
| S/W | 22885 |
Fn3-54 |
45 | None | 0.4078 | None | 0.998 | N | 0.477 | 0.276 | 0.547935346631 | gnomAD-4.0.0 | 6.84426E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15993E-05 | 0 |
| R/Q | 23084 |
Fn3-55 |
45 | rs200191748 |
0.8341 | -0.118 | 0.994 | N | 0.415 | 0.279 | None | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 2.06748E-04 | 0 | None | 0 | 5.15E-05 | None | 0 | None | 4E-05 | 1.57E-05 | 0 |
| R/Q | 23084 |
Fn3-55 |
45 | rs200191748 |
0.8341 | -0.118 | 0.994 | N | 0.415 | 0.279 | None | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 1.45012E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| R/Q | 23084 |
Fn3-55 |
45 | rs200191748 |
0.8341 | -0.118 | 0.994 | N | 0.415 | 0.279 | None | gnomAD-4.0.0 | 2.60362E-05 | None | None | None | None | N | None | 1.20285E-04 | 0 | None | 0 | 4.46568E-05 | None | 0 | 0 | 2.45854E-05 | 0 | 3.20297E-05 |
| D/V | 23284 |
Fn3-57 |
45 | rs768131129 |
0.1303 | 0.283 | 0.317 | N | 0.431 | 0.33 | 0.408853032482 | gnomAD-2.1.1 | 4.22E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.31E-06 | 0 |
| D/V | 23284 |
Fn3-57 |
45 | rs768131129 |
0.1303 | 0.283 | 0.317 | N | 0.431 | 0.33 | 0.408853032482 | gnomAD-4.0.0 | 4.85197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.67624E-06 | 0 | 0 |
| R/Q | 23479 |
Fn3-58 |
45 | rs140127488 |
0.3477 | 0.072 | 0.998 | N | 0.36 | 0.244 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.78E-05 | 0 |
| R/Q | 23479 |
Fn3-58 |
45 | rs140127488 |
0.3477 | 0.072 | 0.998 | N | 0.36 | 0.244 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94099E-04 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 23479 |
Fn3-58 |
45 | rs140127488 |
0.3477 | 0.072 | 0.998 | N | 0.36 | 0.244 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| R/Q | 23479 |
Fn3-58 |
45 | rs140127488 |
0.3477 | 0.072 | 0.998 | N | 0.36 | 0.244 | None | gnomAD-4.0.0 | 1.54944E-05 | None | None | None | None | N | None | 1.33316E-05 | 0 | None | 0 | 2.23454E-05 | None | 0 | 0 | 1.69545E-05 | 3.29417E-05 | 0 |
| R/W | 23479 |
Fn3-58 |
45 | rs760509116 |
0.6242 | -0.376 | 1.0 | N | 0.647 | 0.328 | 0.370424759081 | gnomAD-2.1.1 | 6.08E-05 | None | None | None | None | N | None | 4.13E-05 | 3.67876E-04 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| R/W | 23479 |
Fn3-58 |
45 | rs760509116 |
0.6242 | -0.376 | 1.0 | N | 0.647 | 0.328 | 0.370424759081 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 1.96773E-04 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/W | 23479 |
Fn3-58 |
45 | rs760509116 |
0.6242 | -0.376 | 1.0 | N | 0.647 | 0.328 | 0.370424759081 | gnomAD-4.0.0 | 3.09884E-05 | None | None | None | None | N | None | 3.99957E-05 | 3.16772E-04 | None | 0 | 0 | None | 0 | 0 | 1.86498E-05 | 2.19602E-05 | 6.40307E-05 |
| S/F | 23576 |
Fn3-59 |
45 | None | 0.2572 | None | 0.995 | N | 0.525 | 0.489 | 0.527557778142 | gnomAD-4.0.0 | 1.59174E-06 | None | None | None | None | N | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/C | 23870 |
Fn3-61 |
45 | None | 0.2248 | None | 0.995 | N | 0.683 | 0.364 | 0.580833741332 | gnomAD-4.0.0 | 6.84282E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99567E-07 | 0 | 0 |
| G/S | 23870 |
Fn3-61 |
45 | rs727503564 |
0.0871 | -0.987 | 0.005 | N | 0.294 | 0.103 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.13E-05 | 0 |
| G/S | 23870 |
Fn3-61 |
45 | rs727503564 |
0.0871 | -0.987 | 0.005 | N | 0.294 | 0.103 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 4.78469E-04 |
| G/S | 23870 |
Fn3-61 |
45 | rs727503564 |
0.0871 | -0.987 | 0.005 | N | 0.294 | 0.103 | None | gnomAD-4.0.0 | 1.30159E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.125E-05 | 0 | 1.52591E-05 | 0 | 1.60128E-05 |
| G/V | 23870 |
Fn3-61 |
45 | rs1709389326 |
0.3815 | None | 0.901 | N | 0.675 | 0.277 | 0.611738395503 | gnomAD-4.0.0 | 3.42141E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49785E-06 | 0 | 0 |
| N/T | 23968 |
Fn3-62 |
45 | rs769320596 |
0.0974 | 0.166 | 0.012 | N | 0.282 | 0.069 | 0.203808441222 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 1.99362E-04 | 0 | None | 0 | None | 0 | 1.79E-05 | 1.66113E-04 |
| N/T | 23968 |
Fn3-62 |
45 | rs769320596 |
0.0974 | 0.166 | 0.012 | N | 0.282 | 0.069 | 0.203808441222 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 8.64553E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/T | 23968 |
Fn3-62 |
45 | rs769320596 |
0.0974 | 0.166 | 0.012 | N | 0.282 | 0.069 | 0.203808441222 | gnomAD-4.0.0 | 2.6655E-05 | None | None | None | None | N | None | 0 | 0 | None | 8.1114E-04 | 0 | None | 1.5623E-05 | 0 | 1.18693E-05 | 0 | 6.40594E-05 |
| N/Y | 23968 |
Fn3-62 |
45 | None | 0.1396 | None | 0.093 | N | 0.409 | 0.175 | 0.359357374593 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/D | 24266 |
Fn3-64 |
45 | None | 0.7975 | None | 1.0 | N | 0.586 | 0.442 | 0.38342384377 | gnomAD-4.0.0 | 3.54643E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.93097E-05 | 0 | 0 | 0 | 0 |
| E/A | 24367 |
Fn3-65 |
45 | None | 0.1018 | None | 0.058 | N | 0.298 | 0.137 | 0.19670166235 | gnomAD-4.0.0 | 6.84487E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99675E-07 | 0 | 0 |
| E/D | 24367 |
Fn3-65 |
45 | rs1357419691 |
0.0929 | -0.413 | 0.822 | N | 0.317 | 0.086 | 0.290590437066 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/D | 24367 |
Fn3-65 |
45 | rs1357419691 |
0.0929 | -0.413 | 0.822 | N | 0.317 | 0.086 | 0.290590437066 | gnomAD-4.0.0 | 3.18567E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4334E-05 | 3.02737E-05 |
| E/V | 24367 |
Fn3-65 |
45 | None | 0.1518 | None | 0.698 | N | 0.382 | 0.248 | 0.352262096564 | gnomAD-4.0.0 | 1.36897E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79935E-06 | 0 | 0 |
| R/G | 24563 |
Fn3-66 |
45 | None | 0.9757 | None | 0.021 | N | 0.343 | 0.223 | 0.285316908763 | gnomAD-4.0.0 | 1.59418E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86525E-06 | 0 | 0 |
| R/T | 24563 |
Fn3-66 |
45 | rs560347347 |
0.9934 | -0.213 | 0.98 | N | 0.346 | 0.381 | 0.38242337071 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 24563 |
Fn3-66 |
45 | rs560347347 |
0.9934 | -0.213 | 0.98 | N | 0.346 | 0.381 | 0.38242337071 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| R/T | 24563 |
Fn3-66 |
45 | rs560347347 |
0.9934 | -0.213 | 0.98 | N | 0.346 | 0.381 | 0.38242337071 | gnomAD-4.0.0 | 6.57091E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.94175E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 24660 |
Fn3-67 |
45 | rs1444695129 |
0.1433 | None | 0.973 | N | 0.469 | 0.198 | 0.203808441222 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 24660 |
Fn3-67 |
45 | rs1444695129 |
0.1433 | None | 0.973 | N | 0.469 | 0.198 | 0.203808441222 | gnomAD-4.0.0 | 1.23967E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.64528E-04 | 8.47716E-07 | 0 | 0 |
| T/S | 24853 |
Fn3-68 |
46 | rs756071728 |
0.1167 | -0.216 | 0.958 | N | 0.299 | 0.225 | 0.199424873507 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| T/S | 24853 |
Fn3-68 |
46 | rs756071728 |
0.1167 | -0.216 | 0.958 | N | 0.299 | 0.225 | 0.199424873507 | gnomAD-4.0.0 | 3.18492E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71899E-06 | 0 | 0 |
| E/K | 25050 |
Fn3-70 |
45 | rs770754919 |
0.1714 | -0.096 | 0.012 | N | 0.258 | 0.077 | 0.191931220699 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 25050 |
Fn3-70 |
45 | rs770754919 |
0.1714 | -0.096 | 0.012 | N | 0.258 | 0.077 | 0.191931220699 | gnomAD-4.0.0 | 3.18384E-06 | None | None | None | None | N | None | 0 | 4.57289E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 25249 |
Fn3-71 |
46 | rs397517702 |
0.7085 | -0.358 | 1.0 | N | 0.729 | 0.441 | 0.580315741719 | gnomAD-2.1.1 | 8.2561E-04 | None | None | None | None | I | None | 0 | 5.81E-05 | None | 0 | 0 | None | 6.54365E-03 | None | 0 | 1.79E-05 | 0 |
| R/C | 25249 |
Fn3-71 |
46 | rs397517702 |
0.7085 | -0.358 | 1.0 | N | 0.729 | 0.441 | 0.580315741719 | gnomAD-3.1.2 | 1.77613E-04 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 4.97306E-03 | 4.79846E-04 |
| R/C | 25249 |
Fn3-71 |
46 | rs397517702 |
0.7085 | -0.358 | 1.0 | N | 0.729 | 0.441 | 0.580315741719 | 1000 genomes | 1.19808E-03 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 6.1E-03 | None |
| R/C | 25249 |
Fn3-71 |
46 | rs397517702 |
0.7085 | -0.358 | 1.0 | N | 0.729 | 0.441 | 0.580315741719 | gnomAD-4.0.0 | 4.0232E-04 | None | None | None | None | I | None | 1.33362E-05 | 3.33589E-05 | None | 0 | 0 | None | 0 | 6.60502E-04 | 5.08656E-06 | 6.86285E-03 | 1.76175E-04 |
| R/H | 25249 |
Fn3-71 |
46 | rs773286477 |
0.2925 | -1.08 | 1.0 | N | 0.687 | 0.346 | 0.325263233342 | gnomAD-2.1.1 | 4.45E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-05 | 1.66945E-04 |
| R/H | 25249 |
Fn3-71 |
46 | rs773286477 |
0.2925 | -1.08 | 1.0 | N | 0.687 | 0.346 | 0.325263233342 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/H | 25249 |
Fn3-71 |
46 | rs773286477 |
0.2925 | -1.08 | 1.0 | N | 0.687 | 0.346 | 0.325263233342 | gnomAD-4.0.0 | 3.40965E-05 | None | None | None | None | I | None | 1.33558E-05 | 5.00534E-05 | None | 0 | 6.70991E-05 | None | 0 | 0 | 3.39099E-05 | 3.29388E-05 | 8.01025E-05 |
| G/D | 25348 |
Fn3-72 |
45 | None | 0.8307 | None | 0.988 | N | 0.589 | 0.403 | 0.338834610459 | gnomAD-4.0.0 | 6.84352E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99598E-07 | 0 | 0 |
| G/V | 25348 |
Fn3-72 |
45 | None | 0.6454 | None | 0.988 | N | 0.683 | 0.438 | 0.495372917472 | gnomAD-4.0.0 | 6.84352E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87413E-05 | 0 | 0 | 0 | 0 |
| S/N | 25742 |
Fn3-75 |
45 | rs1707054015 |
0.1507 | None | 0.028 | N | 0.359 | 0.07 | 0.15556083564 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 25742 |
Fn3-75 |
45 | rs1707054015 |
0.1507 | None | 0.028 | N | 0.359 | 0.07 | 0.15556083564 | gnomAD-4.0.0 | 6.57505E-06 | None | None | None | None | N | None | 2.41243E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 25742 |
Fn3-75 |
45 | rs753101927 |
0.5505 | -0.316 | 0.865 | N | 0.322 | 0.216 | 0.262175524916 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/R | 25742 |
Fn3-75 |
45 | rs753101927 |
0.5505 | -0.316 | 0.865 | N | 0.322 | 0.216 | 0.262175524916 | gnomAD-4.0.0 | 1.36885E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79928E-06 | 0 | 0 |
| T/S | 25935 |
Fn3-76 |
46 | None | 0.0992 | None | 0.006 | N | 0.299 | 0.128 | 0.110078149338 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/N | 26034 |
Fn3-77 |
45 | None | 0.6759 | None | 0.983 | N | 0.451 | 0.204 | 0.186928172975 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 26132 |
Fn3-78 |
45 | rs757198030 |
0.0924 | -0.261 | 0.117 | N | 0.296 | 0.188 | 0.256793551483 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 1.29249E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| D/N | 26132 |
Fn3-78 |
45 | rs757198030 |
0.0924 | -0.261 | 0.117 | N | 0.296 | 0.188 | 0.256793551483 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 26132 |
Fn3-78 |
45 | rs757198030 |
0.0924 | -0.261 | 0.117 | N | 0.296 | 0.188 | 0.256793551483 | gnomAD-4.0.0 | 5.58078E-06 | None | None | None | None | N | None | 2.67094E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.9369E-06 | 0 | 0 |
| D/Y | 26132 |
Fn3-78 |
45 | rs757198030 |
0.2806 | None | 0.741 | N | 0.474 | 0.509 | 0.625503179482 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
| D/Y | 26132 |
Fn3-78 |
45 | rs757198030 |
0.2806 | None | 0.741 | N | 0.474 | 0.509 | 0.625503179482 | gnomAD-4.0.0 | 6.84647E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65766E-05 |
| R/Q | 26331 |
Fn3-79 |
46 | rs758190406 |
0.7854 | -0.025 | 1.0 | N | 0.597 | 0.408 | 0.221019684889 | gnomAD-2.1.1 | 2.86E-05 | None | None | None | None | I | None | 2.06731E-04 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 7.85E-06 | 0 |
| R/Q | 26331 |
Fn3-79 |
46 | rs758190406 |
0.7854 | -0.025 | 1.0 | N | 0.597 | 0.408 | 0.221019684889 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | I | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| R/Q | 26331 |
Fn3-79 |
46 | rs758190406 |
0.7854 | -0.025 | 1.0 | N | 0.597 | 0.408 | 0.221019684889 | gnomAD-4.0.0 | 1.61154E-05 | None | None | None | None | I | None | 9.34879E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47745E-06 | 6.58892E-05 | 4.80461E-05 |
| G/A | 26430 |
Fn3-80 |
45 | None | 0.3968 | None | 0.45 | N | 0.505 | 0.337 | 0.256283259241 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
| E/D | 26531 |
Fn3-81 |
45 | None | 0.107 | None | 0.067 | N | 0.253 | 0.073 | 0.256793551483 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| E/K | 26531 |
Fn3-81 |
45 | rs772211147 |
0.1038 | 0.33 | 0.958 | N | 0.437 | 0.354 | 0.356072328145 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| E/K | 26531 |
Fn3-81 |
45 | rs772211147 |
0.1038 | 0.33 | 0.958 | N | 0.437 | 0.354 | 0.356072328145 | gnomAD-4.0.0 | 1.9163E-05 | None | None | None | None | N | None | 0 | 2.23624E-05 | None | 0 | 0 | None | 0 | 0 | 2.33875E-05 | 0 | 1.65695E-05 |
| R/S | 26727 |
Fn3-82 |
45 | rs769497982 |
0.9854 | -0.564 | 1.0 | N | 0.607 | 0.364 | 0.275215494804 | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 3.59712E-04 | 7.83E-06 | 0 |
| R/S | 26727 |
Fn3-82 |
45 | rs769497982 |
0.9854 | -0.564 | 1.0 | N | 0.607 | 0.364 | 0.275215494804 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 2.8222E-04 | 0 | 1.47E-05 | 0 | 0 |
| R/S | 26727 |
Fn3-82 |
45 | rs769497982 |
0.9854 | -0.564 | 1.0 | N | 0.607 | 0.364 | 0.275215494804 | gnomAD-4.0.0 | 3.58777E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.92132E-04 | 0 | 7.18095E-06 | 0 | 0 |
| T/A | 26824 |
Fn3-83 |
45 | rs1237485492 |
0.0774 | -0.458 | 0.001 | N | 0.095 | 0.105 | 0.158396225186 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 26824 |
Fn3-83 |
45 | rs1237485492 |
0.0774 | -0.458 | 0.001 | N | 0.095 | 0.105 | 0.158396225186 | gnomAD-4.0.0 | 1.59157E-06 | None | None | None | None | N | None | 5.65995E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 27017 |
Fn3-84 |
46 | rs993539436 |
0.1216 | -0.8 | 0.174 | N | 0.358 | 0.112 | 0.20549828249 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 27017 |
Fn3-84 |
46 | rs993539436 |
0.1216 | -0.8 | 0.174 | N | 0.358 | 0.112 | 0.20549828249 | gnomAD-4.0.0 | 1.59167E-06 | None | None | None | None | N | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 27116 |
Fn3-85 |
45 | rs780359890 |
0.1212 | -0.863 | 0.011 | N | 0.307 | 0.2 | 0.17948927462 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.74E-05 | None | 0 | None | 0 | 0 | 0 |
| S/G | 27116 |
Fn3-85 |
45 | rs780359890 |
0.1212 | -0.863 | 0.011 | N | 0.307 | 0.2 | 0.17948927462 | gnomAD-4.0.0 | 1.5951E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78784E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 27116 |
Fn3-85 |
45 | rs1234317183 |
0.4155 | -0.441 | 0.892 | N | 0.465 | 0.336 | 0.284150004643 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 2.94E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 27116 |
Fn3-85 |
45 | rs1234317183 |
0.4155 | -0.441 | 0.892 | N | 0.465 | 0.336 | 0.284150004643 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 27116 |
Fn3-85 |
45 | rs1234317183 |
0.4155 | -0.441 | 0.892 | N | 0.465 | 0.336 | 0.284150004643 | gnomAD-4.0.0 | 3.72202E-06 | None | None | None | None | N | None | 0 | 1.67386E-05 | None | 0 | 0 | None | 0 | 0 | 3.39258E-06 | 0 | 1.60333E-05 |
| D/A | 27214 |
Fn3-86 |
45 | rs1704936651 |
0.1341 | None | 0.865 | N | 0.537 | 0.347 | 0.410337123052 | gnomAD-4.0.0 | 3.42485E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.50043E-06 | 0 | 0 |
| D/N | 27214 |
Fn3-86 |
45 | None | 0.0866 | None | 0.978 | N | 0.591 | 0.351 | 0.360961692134 | gnomAD-4.0.0 | 6.85014E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5328E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 27414 |
Fn3-87 |
46 | rs763336230 |
0.5115 | -0.098 | 0.997 | N | 0.397 | 0.24 | 0.238096912614 | gnomAD-2.1.1 | 4.64E-05 | None | None | None | None | N | None | 4.13E-05 | 1.41443E-04 | None | 0 | 5.13E-05 | None | 9.8E-05 | None | 0 | 2.35E-05 | 0 |
| R/Q | 27414 |
Fn3-87 |
46 | rs763336230 |
0.5115 | -0.098 | 0.997 | N | 0.397 | 0.24 | 0.238096912614 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 3.86997E-04 | None | 0 | 0 | 1.47E-05 | 2.07555E-04 | 0 |
| R/Q | 27414 |
Fn3-87 |
46 | rs763336230 |
0.5115 | -0.098 | 0.997 | N | 0.397 | 0.24 | 0.238096912614 | gnomAD-4.0.0 | 2.54092E-05 | None | None | None | None | N | None | 1.33518E-05 | 1.00027E-04 | None | 0 | 6.69045E-05 | None | 0 | 0 | 2.03434E-05 | 7.68656E-05 | 0 |
| G/R | 27513 |
Fn3-88 |
45 | rs957555800 |
0.8353 | -0.239 | 0.997 | N | 0.758 | 0.419 | 0.508398094826 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| G/R | 27513 |
Fn3-88 |
45 | rs957555800 |
0.8353 | -0.239 | 0.997 | N | 0.758 | 0.419 | 0.508398094826 | gnomAD-4.0.0 | 1.36843E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79897E-06 | 0 | 0 |
| G/S | 27513 |
Fn3-88 |
45 | None | 0.1427 | None | 0.778 | N | 0.527 | 0.167 | 0.203808441222 | gnomAD-4.0.0 | 6.84215E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| G/V | 27513 |
Fn3-88 |
45 | rs1704505707 |
0.5103 | None | 0.997 | N | 0.745 | 0.453 | 0.600746198033 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 27513 |
Fn3-88 |
45 | rs1704505707 |
0.5103 | None | 0.997 | N | 0.745 | 0.453 | 0.600746198033 | gnomAD-4.0.0 | 6.57402E-06 | None | None | None | None | N | None | 0 | 6.55394E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/E | 27614 |
Fn3-89 |
45 | rs762964203 |
0.1499 | -0.816 | 0.016 | N | 0.231 | 0.133 | 0.178374595973 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| A/E | 27614 |
Fn3-89 |
45 | rs762964203 |
0.1499 | -0.816 | 0.016 | N | 0.231 | 0.133 | 0.178374595973 | gnomAD-4.0.0 | 6.84268E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99525E-07 | 0 | 0 |
| A/V | 27614 |
Fn3-89 |
45 | rs762964203 |
0.0876 | -0.112 | 0.845 | N | 0.267 | 0.079 | 0.233150807113 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.64E-05 | 0 | 0 |
| A/V | 27614 |
Fn3-89 |
45 | rs762964203 |
0.0876 | -0.112 | 0.845 | N | 0.267 | 0.079 | 0.233150807113 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 27614 |
Fn3-89 |
45 | rs762964203 |
0.0876 | -0.112 | 0.845 | N | 0.267 | 0.079 | 0.233150807113 | gnomAD-4.0.0 | 4.95829E-06 | None | None | None | None | N | None | 1.33551E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08608E-06 | 1.09791E-05 | 0 |
| R/T | 27810 |
Fn3-90 |
45 | None | 0.9663 | None | 0.961 | N | 0.369 | 0.369 | 0.344483371355 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/I | 27907 |
Fn3-91 |
45 | None | 0.1768 | None | 1.0 | N | 0.502 | 0.474 | 0.440604514059 | gnomAD-4.0.0 | 3.42486E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49922E-06 | 0 | 0 |
| S/N | 27907 |
Fn3-91 |
45 | rs759630792 |
0.1507 | -0.11 | 0.91 | N | 0.387 | 0.162 | 0.173771789658 | gnomAD-2.1.1 | 8.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.98138E-04 | None | 0 | 0 | 0 |
| S/N | 27907 |
Fn3-91 |
45 | rs759630792 |
0.1507 | -0.11 | 0.91 | N | 0.387 | 0.162 | 0.173771789658 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 6.20347E-04 | 0 |
| S/N | 27907 |
Fn3-91 |
45 | rs759630792 |
0.1507 | -0.11 | 0.91 | N | 0.387 | 0.162 | 0.173771789658 | gnomAD-4.0.0 | 2.97749E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.07659E-04 | 3.20595E-05 |
| S/R | 27907 |
Fn3-91 |
45 | rs1306149709 |
0.6298 | None | 0.999 | N | 0.407 | 0.354 | 0.282575091529 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 27907 |
Fn3-91 |
45 | rs1306149709 |
0.6298 | None | 0.999 | N | 0.407 | 0.354 | 0.282575091529 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/T | 27907 |
Fn3-91 |
45 | None | 0.0779 | None | 0.953 | N | 0.397 | 0.121 | 0.1749357433 | gnomAD-4.0.0 | 6.84972E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99844E-07 | 0 | 0 |
| S/N | 28198 |
Fn3-93 |
45 | None | 0.5438 | None | 0.983 | N | 0.503 | 0.281 | 0.199424873507 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/T | 28198 |
Fn3-93 |
45 | rs886039057 |
0.2442 | None | 0.892 | D | 0.401 | 0.22 | 0.166414681773 | gnomAD-4.0.0 | 1.20032E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-05 | 0 | 0 |
| H/L | 28495 |
Fn3-95 |
46 | rs554119186 |
0.2834 | 0.492 | 0.006 | N | 0.287 | 0.106 | 0.242244723065 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66058E-04 |
| H/L | 28495 |
Fn3-95 |
46 | rs554119186 |
0.2834 | 0.492 | 0.006 | N | 0.287 | 0.106 | 0.242244723065 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | I | None | 0 | 4.58535E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/L | 28495 |
Fn3-95 |
46 | rs554119186 |
0.2834 | 0.492 | 0.006 | N | 0.287 | 0.106 | 0.242244723065 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| H/L | 28495 |
Fn3-95 |
46 | rs554119186 |
0.2834 | 0.492 | 0.006 | N | 0.287 | 0.106 | 0.242244723065 | gnomAD-4.0.0 | 1.40926E-05 | None | None | None | None | I | None | 0 | 1.69457E-04 | None | 0 | 0 | None | 0 | 0 | 2.39308E-06 | 0 | 0 |
| S/T | 28594 |
Fn3-96 |
45 | rs1703174198 |
0.1437 | None | 0.117 | N | 0.34 | 0.134 | 0.126345400529 | gnomAD-4.0.0 | 1.59153E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77608E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 28695 |
Fn3-97 |
45 | rs759939166 |
0.1032 | 0.268 | 0.22 | N | 0.323 | 0.205 | 0.225902525712 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 0 | 2.03122E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 28695 |
Fn3-97 |
45 | rs759939166 |
0.1032 | 0.268 | 0.22 | N | 0.323 | 0.205 | 0.225902525712 | gnomAD-4.0.0 | 6.15827E-06 | None | None | None | None | N | None | 0 | 1.78899E-04 | None | 0 | 0 | None | 0 | 0 | 8.99455E-07 | 0 | 0 |
| K/T | 28889 |
Fn3-98 |
45 | None | 0.8649 | None | 0.967 | N | 0.425 | 0.33 | 0.327419511103 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/H | 28986 |
Fn3-99 |
45 | rs777381679 |
0.1998 | -0.471 | 0.999 | N | 0.344 | 0.183 | 0.337621943819 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| Q/H | 28986 |
Fn3-99 |
45 | rs777381679 |
0.1998 | -0.471 | 0.999 | N | 0.344 | 0.183 | 0.337621943819 | gnomAD-4.0.0 | 2.05263E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.47802E-05 | 0 |
| Q/R | 28986 |
Fn3-99 |
45 | None | 0.1027 | None | 0.961 | N | 0.334 | 0.242 | 0.228597637076 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 29182 |
Fn3-100 |
46 | rs1215379633 |
0.2833 | None | 0.999 | N | 0.605 | 0.393 | 0.402326594622 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 29182 |
Fn3-100 |
46 | rs1215379633 |
0.2833 | None | 0.999 | N | 0.605 | 0.393 | 0.402326594622 | gnomAD-4.0.0 | 6.56996E-06 | None | None | None | None | N | None | 2.41301E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 29281 |
Fn3-101 |
45 | None | 0.1996 | None | 0.822 | N | 0.306 | 0.218 | 0.286081765059 | gnomAD-4.0.0 | 1.36831E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.5194E-05 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| D/N | 29379 |
Fn3-102 |
45 | rs1285049057 |
0.0798 | -0.071 | 0.005 | N | 0.104 | 0.168 | 0.236890367714 | gnomAD-2.1.1 | 6.37E-05 | None | None | None | None | N | None | 2.29516E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/N | 29379 |
Fn3-102 |
45 | rs1285049057 |
0.0798 | -0.071 | 0.005 | N | 0.104 | 0.168 | 0.236890367714 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 29379 |
Fn3-102 |
45 | rs1285049057 |
0.0798 | -0.071 | 0.005 | N | 0.104 | 0.168 | 0.236890367714 | gnomAD-4.0.0 | 7.68677E-06 | None | None | None | None | N | None | 1.01458E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 29578 |
Fn3-103 |
46 | rs539906386 |
0.881 | -0.471 | 1.0 | N | 0.731 | 0.368 | 0.685689443777 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| R/C | 29578 |
Fn3-103 |
46 | rs539906386 |
0.881 | -0.471 | 1.0 | N | 0.731 | 0.368 | 0.685689443777 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/C | 29578 |
Fn3-103 |
46 | rs539906386 |
0.881 | -0.471 | 1.0 | N | 0.731 | 0.368 | 0.685689443777 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| R/C | 29578 |
Fn3-103 |
46 | rs539906386 |
0.881 | -0.471 | 1.0 | N | 0.731 | 0.368 | 0.685689443777 | gnomAD-4.0.0 | 3.09824E-06 | None | None | None | None | I | None | 0 | 1.66639E-05 | None | 0 | 4.45911E-05 | None | 0 | 0 | 1.69515E-06 | 0 | 0 |
| R/H | 29578 |
Fn3-103 |
46 | rs374147064 |
0.6021 | -1.271 | 1.0 | N | 0.679 | 0.371 | None | gnomAD-2.1.1 | 1.3924E-04 | None | None | None | None | I | None | 1.07465E-03 | 1.13109E-04 | None | 0 | 3.58938E-04 | None | 3.27E-05 | None | 0 | 0 | 1.40371E-04 |
| R/H | 29578 |
Fn3-103 |
46 | rs374147064 |
0.6021 | -1.271 | 1.0 | N | 0.679 | 0.371 | None | gnomAD-3.1.2 | 3.08946E-04 | None | None | None | None | I | None | 8.69103E-04 | 0 | 0 | 0 | 1.93125E-03 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| R/H | 29578 |
Fn3-103 |
46 | rs374147064 |
0.6021 | -1.271 | 1.0 | N | 0.679 | 0.371 | None | 1000 genomes | 1.39776E-03 | None | None | None | None | I | None | 1.5E-03 | 0 | None | None | 5E-03 | 0 | None | None | None | 0 | None |
| R/H | 29578 |
Fn3-103 |
46 | rs374147064 |
0.6021 | -1.271 | 1.0 | N | 0.679 | 0.371 | None | gnomAD-4.0.0 | 6.75395E-05 | None | None | None | None | I | None | 9.06401E-04 | 8.33139E-05 | None | 0 | 3.78991E-04 | None | 1.56221E-05 | 0 | 4.23789E-06 | 1.09794E-05 | 1.92049E-04 |
| S/R | 29677 |
Fn3-104 |
45 | None | 0.8592 | None | 1.0 | N | 0.614 | 0.416 | 0.273070737957 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85799E-06 | 0 | 0 |
| S/R | 30368 |
Fn3-109 |
45 | rs1377525148 |
0.9643 | -0.219 | 1.0 | N | 0.573 | 0.548 | 0.40318662893 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| S/R | 30368 |
Fn3-109 |
45 | rs1377525148 |
0.9643 | -0.219 | 1.0 | N | 0.573 | 0.548 | 0.40318662893 | gnomAD-4.0.0 | 1.59119E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/I | 30664 |
Fn3-111 |
46 | None | 0.9606 | None | 1.0 | D | 0.693 | 0.492 | 0.727100791208 | gnomAD-4.0.0 | 6.84242E-07 | None | None | None | None | N | None | 0 | 0 | None | 3.8276E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/S | 30664 |
Fn3-111 |
46 | None | 0.9778 | None | 1.0 | N | 0.573 | 0.369 | 0.259272394797 | gnomAD-4.0.0 | 1.59141E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76781E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 30865 |
Fn3-113 |
45 | rs192086736 |
0.1094 | None | 0.996 | N | 0.583 | 0.219 | 0.28722502521 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/F | 30865 |
Fn3-113 |
45 | rs192086736 |
0.1094 | None | 0.996 | N | 0.583 | 0.219 | 0.28722502521 | gnomAD-4.0.0 | 6.57022E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46977E-05 | 0 | 0 |
| R/C | 31060 |
Fn3-114 |
45 | rs750303653 |
0.4435 | -0.476 | 1.0 | N | 0.723 | 0.506 | 0.753210536836 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 9.8E-05 | None | 0 | 8.92E-06 | 1.65782E-04 |
| R/C | 31060 |
Fn3-114 |
45 | rs750303653 |
0.4435 | -0.476 | 1.0 | N | 0.723 | 0.506 | 0.753210536836 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07297E-04 | 0 |
| R/C | 31060 |
Fn3-114 |
45 | rs750303653 |
0.4435 | -0.476 | 1.0 | N | 0.723 | 0.506 | 0.753210536836 | gnomAD-4.0.0 | 1.92106E-05 | None | None | None | None | N | None | 0 | 5.00083E-05 | None | 0 | 0 | None | 0 | 0 | 1.18663E-05 | 1.42741E-04 | 1.60102E-05 |
| R/H | 31060 |
Fn3-114 |
45 | rs776018262 |
0.276 | -1.298 | 1.0 | N | 0.667 | 0.455 | 0.323342291347 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 0 | 5.13E-05 | None | 3.27E-05 | None | 0 | 1.57E-05 | 0 |
| R/H | 31060 |
Fn3-114 |
45 | rs776018262 |
0.276 | -1.298 | 1.0 | N | 0.667 | 0.455 | 0.323342291347 | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 4.83E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| R/H | 31060 |
Fn3-114 |
45 | rs776018262 |
0.276 | -1.298 | 1.0 | N | 0.667 | 0.455 | 0.323342291347 | gnomAD-4.0.0 | 2.54071E-05 | None | None | None | None | N | None | 4.00491E-05 | 3.33411E-05 | None | 0 | 0 | None | 0 | 0 | 2.28852E-05 | 7.68521E-05 | 3.20195E-05 |
| R/S | 31060 |
Fn3-114 |
45 | None | 0.9318 | None | 1.0 | N | 0.585 | 0.452 | 0.400756358115 | gnomAD-4.0.0 | 6.84187E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99442E-07 | 0 | 0 |
| T/A | 31353 |
Fn3-116 |
46 | None | 0.1089 | None | 0.027 | N | 0.32 | 0.083 | 0.203808441222 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 31452 |
Fn3-117 |
45 | rs1270325139 |
0.8502 | -0.546 | 0.999 | N | 0.551 | 0.372 | 0.370608029945 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65508E-04 |
| T/K | 31452 |
Fn3-117 |
45 | rs1270325139 |
0.8502 | -0.546 | 0.999 | N | 0.551 | 0.372 | 0.370608029945 | gnomAD-4.0.0 | 1.59117E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88239E-05 | 0 | 0 | 0 | 0 |
| S/N | 31851 |
Fn3-120 |
45 | rs746468000 |
0.3591 | -0.357 | 0.999 | N | 0.465 | 0.26 | 0.207176502487 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/N | 31851 |
Fn3-120 |
45 | rs746468000 |
0.3591 | -0.357 | 0.999 | N | 0.465 | 0.26 | 0.207176502487 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07555E-04 | 0 |
| S/N | 31851 |
Fn3-120 |
45 | rs746468000 |
0.3591 | -0.357 | 0.999 | N | 0.465 | 0.26 | 0.207176502487 | gnomAD-4.0.0 | 1.23945E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09801E-05 | 1.60128E-05 |
| T/S | 31953 |
Fn3-121 |
45 | None | 0.0836 | None | 0.103 | N | 0.163 | 0.047 | 0.104622674875 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85869E-06 | 0 | 0 |
| M/I | 32149 |
Fn3-122 |
45 | rs886042242 |
0.8051 | 0.213 | 0.828 | N | 0.369 | 0.254 | 0.530948259028 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/I | 32149 |
Fn3-122 |
45 | rs886042242 |
0.8051 | 0.213 | 0.828 | N | 0.369 | 0.254 | 0.530948259028 | gnomAD-4.0.0 | 1.59257E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| M/R | 32149 |
Fn3-122 |
45 | rs766743444 |
0.3431 | None | 0.998 | N | 0.329 | 0.527 | 0.625177984591 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/R | 32149 |
Fn3-122 |
45 | rs766743444 |
0.3431 | None | 0.998 | N | 0.329 | 0.527 | 0.625177984591 | gnomAD-4.0.0 | 4.96064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.7841E-06 | 0 | 0 |
| M/T | 32149 |
Fn3-122 |
45 | rs766743444 |
0.471 | 0.465 | 0.979 | N | 0.292 | 0.457 | 0.637230306968 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| M/T | 32149 |
Fn3-122 |
45 | rs766743444 |
0.471 | 0.465 | 0.979 | N | 0.292 | 0.457 | 0.637230306968 | gnomAD-4.0.0 | 2.0538E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.04465E-05 | None | 0 | 0 | 8.99776E-07 | 0 | 0 |
| M/V | 32149 |
Fn3-122 |
45 | rs972033083 |
0.1985 | 0.066 | 0.828 | N | 0.307 | 0.242 | 0.517322629239 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| M/V | 32149 |
Fn3-122 |
45 | rs972033083 |
0.1985 | 0.066 | 0.828 | N | 0.307 | 0.242 | 0.517322629239 | gnomAD-4.0.0 | 4.77794E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71765E-06 | 1.43312E-05 | 0 |
| T/I | 32246 |
Fn3-123 |
45 | None | 0.3954 | None | 0.998 | N | 0.483 | 0.397 | 0.429552544315 | gnomAD-4.0.0 | 2.05258E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69838E-06 | 0 | 0 |
| T/K | 32246 |
Fn3-123 |
45 | rs1300990720 |
0.3199 | None | 0.997 | N | 0.467 | 0.384 | 0.363158594168 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93498E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 32246 |
Fn3-123 |
45 | rs1300990720 |
0.3199 | None | 0.997 | N | 0.467 | 0.384 | 0.363158594168 | gnomAD-4.0.0 | 6.58181E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93498E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 32246 |
Fn3-123 |
45 | rs1300990720 |
0.2877 | -0.081 | 0.998 | N | 0.473 | 0.382 | 0.413503789086 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| T/R | 32246 |
Fn3-123 |
45 | rs1300990720 |
0.2877 | -0.081 | 0.998 | N | 0.473 | 0.382 | 0.413503789086 | gnomAD-4.0.0 | 4.10516E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.4973E-06 | 1.15934E-05 | 0 |
| R/C | 32444 |
Fn3-124 |
46 | rs776164829 |
0.3872 | 0.107 | 1.0 | N | 0.722 | 0.446 | 0.661710244528 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| R/C | 32444 |
Fn3-124 |
46 | rs776164829 |
0.3872 | 0.107 | 1.0 | N | 0.722 | 0.446 | 0.661710244528 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 2.06954E-04 | 0 |
| R/C | 32444 |
Fn3-124 |
46 | rs776164829 |
0.3872 | 0.107 | 1.0 | N | 0.722 | 0.446 | 0.661710244528 | gnomAD-4.0.0 | 2.16912E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.64528E-04 | 2.79725E-05 | 1.09782E-05 | 0 |
| R/H | 32444 |
Fn3-124 |
46 | rs184922462 |
0.2078 | -1.123 | 1.0 | N | 0.67 | 0.31 | 0.285698343383 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 1.16077E-04 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| R/H | 32444 |
Fn3-124 |
46 | rs184922462 |
0.2078 | -1.123 | 1.0 | N | 0.67 | 0.31 | 0.285698343383 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 9.56023E-04 |
| R/H | 32444 |
Fn3-124 |
46 | rs184922462 |
0.2078 | -1.123 | 1.0 | N | 0.67 | 0.31 | 0.285698343383 | gnomAD-4.0.0 | 4.09039E-05 | None | None | None | None | N | None | 0 | 1.00023E-04 | None | 0 | 0 | None | 0 | 0 | 4.74692E-05 | 0 | 6.40471E-05 |
| R/P | 32444 |
Fn3-124 |
46 | rs184922462 |
0.9761 | 0.447 | 1.0 | N | 0.592 | 0.428 | None | gnomAD-2.1.1 | 2.71667E-04 | None | None | None | None | N | None | 0 | 1.16121E-03 | None | 0 | 0 | None | 0 | None | 0 | 2.26974E-04 | 8.43882E-04 |
| R/P | 32444 |
Fn3-124 |
46 | rs184922462 |
0.9761 | 0.447 | 1.0 | N | 0.592 | 0.428 | None | gnomAD-3.1.2 | 2.89249E-04 | None | None | None | None | N | None | 4.83E-05 | 1.76817E-03 | 0 | 0 | 0 | None | 0 | 0 | 1.76465E-04 | 0 | 1.43403E-03 |
| R/P | 32444 |
Fn3-124 |
46 | rs184922462 |
0.9761 | 0.447 | 1.0 | N | 0.592 | 0.428 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| R/P | 32444 |
Fn3-124 |
46 | rs184922462 |
0.9761 | 0.447 | 1.0 | N | 0.592 | 0.428 | None | gnomAD-4.0.0 | 2.41067E-04 | None | None | None | None | N | None | 7.99723E-05 | 1.49985E-03 | None | 0 | 0 | None | 0 | 0 | 2.28023E-04 | 0 | 3.84148E-04 |
| A/G | 32543 |
Fn3-125 |
45 | rs747893721 |
0.1117 | -0.803 | 0.489 | N | 0.39 | 0.387 | 0.245660935333 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| A/G | 32543 |
Fn3-125 |
45 | rs747893721 |
0.1117 | -0.803 | 0.489 | N | 0.39 | 0.387 | 0.245660935333 | gnomAD-4.0.0 | 1.36869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79921E-06 | 0 | 0 |
| A/T | 32543 |
Fn3-125 |
45 | rs1289223812 |
0.1191 | -0.745 | 0.698 | N | 0.337 | 0.185 | 0.198526703765 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65893E-04 |
| A/T | 32543 |
Fn3-125 |
45 | rs1289223812 |
0.1191 | -0.745 | 0.698 | N | 0.337 | 0.185 | 0.198526703765 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 32543 |
Fn3-125 |
45 | rs1289223812 |
0.1191 | -0.745 | 0.698 | N | 0.337 | 0.185 | 0.198526703765 | gnomAD-4.0.0 | 6.19882E-06 | None | None | None | None | N | None | 0 | 0 | None | 6.7595E-05 | 0 | None | 0 | 0 | 3.39114E-06 | 0 | 6.40697E-05 |
| Q/H | 32644 |
Fn3-126 |
45 | rs773841779 |
0.2715 | -0.789 | 0.999 | N | 0.434 | 0.239 | 0.184867976434 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22544E-04 | None | 0 | None | 0 | 0 | 0 |
| Q/H | 32644 |
Fn3-126 |
45 | rs773841779 |
0.2715 | -0.789 | 0.999 | N | 0.434 | 0.239 | 0.184867976434 | gnomAD-4.0.0 | 3.42098E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.25945E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 33335 |
Fn3-130 |
46 | rs779632637 |
0.1319 | 0.061 | 0.999 | N | 0.437 | 0.24 | 0.381746406553 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| E/D | 33335 |
Fn3-130 |
46 | rs779632637 |
0.1319 | 0.061 | 0.999 | N | 0.437 | 0.24 | 0.381746406553 | gnomAD-4.0.0 | 3.18546E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72001E-06 | 0 | 0 |
| E/K | 33335 |
Fn3-130 |
46 | None | 0.1839 | None | 0.999 | N | 0.555 | 0.479 | 0.357929162469 | gnomAD-4.0.0 | 4.10669E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59847E-06 | 0 | 3.31477E-05 |
| Q/H | 33436 |
Fn3-131 |
45 | rs1403079521 |
0.4386 | -1.073 | 0.998 | N | 0.386 | 0.223 | 0.265929055128 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Q/H | 33436 |
Fn3-131 |
45 | rs1403079521 |
0.4386 | -1.073 | 0.998 | N | 0.386 | 0.223 | 0.265929055128 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Q/H | 33436 |
Fn3-131 |
45 | rs1403079521 |
0.4386 | -1.073 | 0.998 | N | 0.386 | 0.223 | 0.265929055128 | gnomAD-4.0.0 | 3.72126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08905E-06 | 0 | 0 |
| Q/K | 33436 |
Fn3-131 |
45 | None | 0.1619 | None | 0.248 | N | 0.28 | 0.175 | 0.187945064343 | gnomAD-4.0.0 | 6.84918E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16114E-05 | 0 |
| A/V | 33733 |
Fn3-132 |
45 | None | 0.5084 | None | 0.883 | N | 0.387 | 0.205 | 0.371344866733 | gnomAD-4.0.0 | 3.18238E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88352E-05 | 0 | 2.85807E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.