Structural position:
- Domain Type: Fn3
- Aligned Position: 91
- Secondary Structure Element: e
- Secondary Structure Region: β-strand E
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| H/Q | 16610 |
Fn3-8 |
60 | None | 0.482 | None | 0.999 | N | 0.479 | 0.348 | 0.181679512989 | gnomAD-4.0.0 | 3.18759E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.83793E-04 | 0 | 0 | 0 |
| F/C | 16912 |
Fn3-11 |
61 | rs2056317849 |
0.3523 | None | 0.009 | N | 0.491 | 0.257 | 0.455722563999 | gnomAD-4.0.0 | 3.42256E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.5991E-06 | 0 | 1.65777E-05 |
| W/R | 17106 |
Fn3-12 |
60 | rs1360832418 |
0.9346 | -1.808 | 1.0 | N | 0.886 | 0.554 | 0.51748813702 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.64E-05 | 0 | 0 |
| W/R | 17106 |
Fn3-12 |
60 | rs1360832418 |
0.9346 | -1.808 | 1.0 | N | 0.886 | 0.554 | 0.51748813702 | gnomAD-4.0.0 | 3.42242E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 5.61798E-05 | 0 | 0 | 2.31927E-05 | 0 |
| A/T | 17529 |
Fn3-15 |
60 | rs1379034586 |
0.0732 | -1.234 | None | N | 0.111 | 0.054 | 0.12205267543 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| A/T | 17529 |
Fn3-15 |
60 | rs1379034586 |
0.0732 | -1.234 | None | N | 0.111 | 0.054 | 0.12205267543 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 17529 |
Fn3-15 |
60 | rs1379034586 |
0.0732 | -1.234 | None | N | 0.111 | 0.054 | 0.12205267543 | gnomAD-4.0.0 | 3.72166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08847E-06 | 0 | 0 |
| Y/C | 17629 |
Fn3-16 |
61 | rs1039650213 |
0.3325 | None | 0.915 | N | 0.601 | 0.353 | 0.499793596984 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 17629 |
Fn3-16 |
61 | rs1039650213 |
0.3325 | None | 0.915 | N | 0.601 | 0.353 | 0.499793596984 | gnomAD-4.0.0 | 3.04544E-06 | None | None | None | None | N | None | 0 | 6.16827E-05 | None | 0 | 0 | None | 0 | 0 | 1.20507E-06 | 0 | 3.40252E-05 |
| Y/F | 17629 |
Fn3-16 |
61 | None | 0.0859 | None | None | N | 0.168 | 0.074 | 0.220303561663 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/L | 18231 |
Fn3-20 |
66 | None | 0.9706 | None | 0.201 | N | 0.664 | 0.216 | 0.119812018005 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 18334 |
Fn3-21 |
63 | rs1375579390 |
0.5985 | None | 0.602 | N | 0.645 | 0.424 | 0.706878895572 | gnomAD-4.0.0 | 8.21536E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19885E-06 | 0 | 6.6313E-05 |
| F/S | 18538 |
Fn3-22 |
60 | None | 0.7785 | None | 0.801 | N | 0.549 | 0.349 | 0.68170140072 | gnomAD-4.0.0 | 1.59342E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4346E-05 | 0 |
| F/L | 18644 |
Fn3-23 |
66 | rs2154192554 |
0.9712 | None | 0.999 | N | 0.576 | 0.492 | 0.392855499163 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07555E-04 | 0 |
| F/L | 18644 |
Fn3-23 |
66 | rs2154192554 |
0.9712 | None | 0.999 | N | 0.576 | 0.492 | 0.392855499163 | gnomAD-4.0.0 | 6.578E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07727E-04 | 0 |
| F/Y | 18644 |
Fn3-23 |
66 | rs879101964 |
0.1943 | -0.768 | 0.999 | N | 0.511 | 0.371 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| F/Y | 18644 |
Fn3-23 |
66 | rs879101964 |
0.1943 | -0.768 | 0.999 | N | 0.511 | 0.371 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/Y | 18644 |
Fn3-23 |
66 | rs879101964 |
0.1943 | -0.768 | 0.999 | N | 0.511 | 0.371 | None | gnomAD-4.0.0 | 2.56481E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.79136E-06 | 0 | 0 |
| A/P | 19243 |
Fn3-27 |
61 | rs1313667626 |
0.9799 | 0.002 | 1.0 | N | 0.833 | 0.55 | 0.51792882206 | gnomAD-2.1.1 | 4.29E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.56E-06 | 0 |
| A/P | 19243 |
Fn3-27 |
61 | rs1313667626 |
0.9799 | 0.002 | 1.0 | N | 0.833 | 0.55 | 0.51792882206 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/P | 19243 |
Fn3-27 |
61 | rs1313667626 |
0.9799 | 0.002 | 1.0 | N | 0.833 | 0.55 | 0.51792882206 | gnomAD-4.0.0 | 4.99061E-06 | None | None | None | None | N | None | 0 | 1.70509E-05 | None | 0 | 0 | None | 0 | 0 | 5.10856E-06 | 0 | 1.61031E-05 |
| C/F | 19539 |
Fn3-29 |
61 | rs539868284 |
0.2373 | -1.027 | 1.0 | N | 0.853 | 0.424 | 0.746742446189 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| C/F | 19539 |
Fn3-29 |
61 | rs539868284 |
0.2373 | -1.027 | 1.0 | N | 0.853 | 0.424 | 0.746742446189 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/F | 19539 |
Fn3-29 |
61 | rs539868284 |
0.2373 | -1.027 | 1.0 | N | 0.853 | 0.424 | 0.746742446189 | gnomAD-4.0.0 | 6.81905E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32535E-06 | 0 | 0 |
| C/R | 19539 |
Fn3-29 |
61 | rs753678261 |
0.8281 | -0.431 | 1.0 | N | 0.875 | 0.545 | 0.825775482533 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.92773E-04 | None | 0 | None | 0 | 0 | 0 |
| C/R | 19539 |
Fn3-29 |
61 | rs753678261 |
0.8281 | -0.431 | 1.0 | N | 0.875 | 0.545 | 0.825775482533 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 5.82072E-04 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 19539 |
Fn3-29 |
61 | rs753678261 |
0.8281 | -0.431 | 1.0 | N | 0.875 | 0.545 | 0.825775482533 | gnomAD-4.0.0 | 1.05377E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.5775E-04 | None | 0 | 0 | 0 | 0 | 1.60149E-05 |
| C/S | 19539 |
Fn3-29 |
61 | rs753678261 |
0.549 | -1.141 | 1.0 | N | 0.689 | 0.546 | 0.694136321851 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| C/S | 19539 |
Fn3-29 |
61 | rs753678261 |
0.549 | -1.141 | 1.0 | N | 0.689 | 0.546 | 0.694136321851 | gnomAD-4.0.0 | 1.36875E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79915E-06 | 0 | 0 |
| Y/C | 19742 |
Fn3-31 |
63 | rs1559607092 |
0.3705 | None | 0.997 | N | 0.584 | 0.388 | 0.454238212503 | gnomAD-4.0.0 | 5.47446E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29713E-06 | 1.15947E-05 | 0 |
| C/F | 20035 |
Fn3-33 |
59 | rs774488793 |
0.3625 | -0.954 | 0.999 | N | 0.751 | 0.402 | 0.766156292133 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.89E-06 | 0 |
| C/F | 20035 |
Fn3-33 |
59 | rs774488793 |
0.3625 | -0.954 | 0.999 | N | 0.751 | 0.402 | 0.766156292133 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07469E-04 | 0 |
| C/F | 20035 |
Fn3-33 |
59 | rs774488793 |
0.3625 | -0.954 | 0.999 | N | 0.751 | 0.402 | 0.766156292133 | gnomAD-4.0.0 | 5.57882E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.64582E-04 | 2.54335E-06 | 3.2946E-05 | 3.20246E-05 |
| C/R | 20035 |
Fn3-33 |
59 | None | 0.8928 | None | 0.997 | N | 0.803 | 0.465 | 0.84113199936 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.21507E-04 | 0 |
| C/Y | 20035 |
Fn3-33 |
59 | rs774488793 |
0.4681 | -1.035 | 0.999 | N | 0.761 | 0.406 | 0.675375996808 | gnomAD-2.1.1 | 6.38E-05 | None | None | None | None | N | None | 2.29674E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 20035 |
Fn3-33 |
59 | rs774488793 |
0.4681 | -1.035 | 0.999 | N | 0.761 | 0.406 | 0.675375996808 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 20035 |
Fn3-33 |
59 | rs774488793 |
0.4681 | -1.035 | 0.999 | N | 0.761 | 0.406 | 0.675375996808 | gnomAD-4.0.0 | 1.85961E-06 | None | None | None | None | N | None | 4.00684E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 20330 |
Fn3-35 |
60 | rs780137240 |
0.2361 | -1.454 | 0.999 | N | 0.681 | 0.372 | 0.321951552304 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.3E-05 | None | 0 | 0 | 0 |
| F/C | 20330 |
Fn3-35 |
60 | rs780137240 |
0.2361 | -1.454 | 0.999 | N | 0.681 | 0.372 | 0.321951552304 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 7.32654E-05 |
| F/L | 20330 |
Fn3-35 |
60 | rs2050031384 |
0.8046 | -1.377 | 0.64 | N | 0.451 | 0.347 | 0.171388866994 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.97837E-04 | None | 0 | 0 | 0 |
| F/L | 20330 |
Fn3-35 |
60 | rs2050031384 |
0.8046 | -1.377 | 0.64 | N | 0.451 | 0.347 | 0.171388866994 | gnomAD-4.0.0 | 9.58986E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.39532E-04 | 3.31741E-05 |
| F/S | 20432 |
Fn3-36 |
62 | None | 0.9533 | None | 0.782 | N | 0.58 | 0.377 | 0.66614110018 | gnomAD-4.0.0 | 3.18971E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.87985E-05 | 0 |
| F/V | 20432 |
Fn3-36 |
62 | rs1287181968 |
0.7717 | -1.719 | 0.505 | N | 0.457 | 0.386 | 0.586295999888 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| F/V | 20432 |
Fn3-36 |
62 | rs1287181968 |
0.7717 | -1.719 | 0.505 | N | 0.457 | 0.386 | 0.586295999888 | gnomAD-4.0.0 | 1.59484E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86302E-06 | 0 | 0 |
| L/S | 20627 |
Fn3-37 |
59 | None | 0.358 | None | 0.001 | N | 0.479 | 0.32 | 0.527809512145 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 20923 |
Fn3-39 |
60 | None | 0.0556 | None | None | N | 0.162 | 0.077 | 0.0611884634855 | gnomAD-4.0.0 | 1.59402E-06 | None | None | None | None | N | None | 0 | 2.2919E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 20923 |
Fn3-39 |
60 | rs781000091 |
0.0938 | 0.094 | 0.062 | N | 0.608 | 0.075 | 0.260249123532 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| M/I | 21023 |
Fn3-40 |
61 | rs1060500596 |
0.2806 | None | 0.012 | N | 0.327 | 0.099 | 0.203808441222 | gnomAD-4.0.0 | 4.79745E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.76598E-04 | None | 0 | 0 | 0 | 0 | 0 |
| M/K | 21023 |
Fn3-40 |
61 | rs754385637 |
0.1775 | -0.782 | None | N | 0.209 | 0.286 | 0.510642626009 | gnomAD-2.1.1 | 2.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.99601E-04 | None | 0 | 0 | 0 |
| M/K | 21023 |
Fn3-40 |
61 | rs754385637 |
0.1775 | -0.782 | None | N | 0.209 | 0.286 | 0.510642626009 | gnomAD-4.0.0 | 8.22266E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00124E-07 | 1.16675E-04 | 1.6592E-05 |
| M/V | 21023 |
Fn3-40 |
61 | None | 0.11 | None | 0.005 | N | 0.261 | 0.163 | 0.0482279557977 | gnomAD-4.0.0 | 1.59669E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44392E-05 | 0 |
| F/L | 21130 |
Fn3-41 |
67 | rs1389556175 |
0.9608 | None | 0.885 | N | 0.493 | 0.321 | 0.276898752692 | gnomAD-4.0.0 | 2.05369E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69928E-06 | 0 | 0 |
| L/F | 21426 |
Fn3-43 |
61 | rs1235011285 |
0.2354 | -1.136 | 0.901 | N | 0.675 | 0.248 | 0.528561964389 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.64E-05 | 0 | 0 |
| L/F | 21426 |
Fn3-43 |
61 | rs1235011285 |
0.2354 | -1.136 | 0.901 | N | 0.675 | 0.248 | 0.528561964389 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.43E-05 | 0 | 0 | 0 | 0 |
| L/F | 21426 |
Fn3-43 |
61 | rs1235011285 |
0.2354 | -1.136 | 0.901 | N | 0.675 | 0.248 | 0.528561964389 | gnomAD-4.0.0 | 5.12877E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.70736E-05 | 0 | 2.39515E-06 | 0 | 0 |
| C/R | 21619 |
Fn3-44 |
61 | rs1486149342 |
0.9506 | -0.126 | 0.999 | D | 0.826 | 0.544 | 0.803198302387 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| C/R | 21619 |
Fn3-44 |
61 | rs1486149342 |
0.9506 | -0.126 | 0.999 | D | 0.826 | 0.544 | 0.803198302387 | gnomAD-4.0.0 | 1.59185E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85971E-06 | 0 | 0 |
| C/W | 21619 |
Fn3-44 |
61 | None | 0.8649 | None | 1.0 | N | 0.737 | 0.408 | 0.460616323599 | gnomAD-4.0.0 | 1.59185E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| Y/C | 21719 |
Fn3-45 |
61 | rs762352911 |
0.7022 | -1.273 | 1.0 | N | 0.837 | 0.492 | 0.587632265475 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/C | 21719 |
Fn3-45 |
61 | rs762352911 |
0.7022 | -1.273 | 1.0 | N | 0.837 | 0.492 | 0.587632265475 | gnomAD-4.0.0 | 6.36898E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.14407E-05 | 0 | 0 |
| L/F | 22115 |
Fn3-48 |
61 | rs371010572 |
0.136 | None | 0.317 | N | 0.461 | 0.049 | 0.180583059064 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 1.14837E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/F | 22115 |
Fn3-48 |
61 | rs371010572 |
0.136 | None | 0.317 | N | 0.461 | 0.049 | 0.180583059064 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 22115 |
Fn3-48 |
61 | rs371010572 |
0.136 | None | 0.317 | N | 0.461 | 0.049 | 0.180583059064 | gnomAD-4.0.0 | 3.84555E-06 | None | None | None | None | I | None | 5.07872E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 22217 |
Fn3-49 |
62 | rs764330098 |
0.6026 | -1.875 | 0.999 | N | 0.707 | 0.356 | 0.634863882896 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 5.67E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.40964E-04 |
| F/C | 22217 |
Fn3-49 |
62 | rs764330098 |
0.6026 | -1.875 | 0.999 | N | 0.707 | 0.356 | 0.634863882896 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| F/C | 22217 |
Fn3-49 |
62 | rs764330098 |
0.6026 | -1.875 | 0.999 | N | 0.707 | 0.356 | 0.634863882896 | gnomAD-4.0.0 | 1.55021E-05 | None | None | None | None | N | None | 0 | 8.34335E-05 | None | 0 | 0 | None | 0 | 0 | 1.69599E-05 | 0 | 0 |
| F/L | 22217 |
Fn3-49 |
62 | None | 0.9507 | None | 0.885 | N | 0.475 | 0.323 | 0.204665344411 | gnomAD-4.0.0 | 1.20043E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31262E-06 | 0 | 0 |
| F/L | 22413 |
Fn3-50 |
60 | rs2047352976 |
0.9347 | None | 0.014 | N | 0.283 | 0.315 | 0.220303561663 | gnomAD-4.0.0 | 3.42194E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79936E-06 | 3.47858E-05 | 0 |
| F/S | 22413 |
Fn3-50 |
60 | rs769934781 |
0.8583 | -2.788 | 0.97 | N | 0.597 | 0.394 | 0.684819293543 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.56E-05 | 0 |
| F/S | 22413 |
Fn3-50 |
60 | rs769934781 |
0.8583 | -2.788 | 0.97 | N | 0.597 | 0.394 | 0.684819293543 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| F/S | 22413 |
Fn3-50 |
60 | rs769934781 |
0.8583 | -2.788 | 0.97 | N | 0.597 | 0.394 | 0.684819293543 | gnomAD-4.0.0 | 1.1537E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.15516E-05 | 0 | 0 |
| F/V | 22413 |
Fn3-50 |
60 | None | 0.5448 | None | 0.698 | N | 0.489 | 0.42 | 0.560190409015 | gnomAD-4.0.0 | 6.84389E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99679E-07 | 0 | 0 |
| Y/D | 22508 |
Fn3-51 |
58 | rs763377678 |
0.7507 | -3.301 | 0.81 | N | 0.717 | 0.453 | 0.600613607152 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.7E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/D | 22508 |
Fn3-51 |
58 | rs763377678 |
0.7507 | -3.301 | 0.81 | N | 0.717 | 0.453 | 0.600613607152 | gnomAD-4.0.0 | 3.18439E-06 | None | None | None | None | N | None | 0 | 4.57519E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 22508 |
Fn3-51 |
58 | None | 0.0921 | None | 0.004 | N | 0.155 | 0.211 | 0.332386209738 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/N | 22508 |
Fn3-51 |
58 | None | 0.5002 | -3.009 | 0.81 | N | 0.682 | 0.358 | None | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| Y/N | 22508 |
Fn3-51 |
58 | None | 0.5002 | -3.009 | 0.81 | N | 0.682 | 0.358 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/N | 22508 |
Fn3-51 |
58 | None | 0.5002 | -3.009 | 0.81 | N | 0.682 | 0.358 | None | gnomAD-4.0.0 | 6.57652E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47063E-05 | 0 | 0 |
| F/C | 22703 |
Fn3-52 |
61 | rs2047065698 |
0.4091 | None | 0.999 | N | 0.583 | 0.488 | 0.687538048876 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 22703 |
Fn3-52 |
61 | rs2047065698 |
0.4091 | None | 0.999 | N | 0.583 | 0.488 | 0.687538048876 | gnomAD-4.0.0 | 6.58068E-06 | None | None | None | None | N | None | 0 | 6.55824E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 22803 |
Fn3-53 |
61 | None | 0.8428 | None | 0.309 | N | 0.473 | 0.304 | 0.369867359543 | gnomAD-4.0.0 | 6.84414E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65711E-05 |
| F/V | 22803 |
Fn3-53 |
61 | None | 0.3308 | None | 0.684 | N | 0.493 | 0.377 | 0.617576649361 | gnomAD-4.0.0 | 2.05323E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79934E-06 | 0 | 1.65706E-05 |
| F/Y | 22901 |
Fn3-54 |
61 | None | 0.2162 | None | None | N | 0.16 | 0.091 | None | gnomAD-4.0.0 | 1.59212E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85958E-06 | 0 | 0 |
| C/R | 23199 |
Fn3-56 |
61 | rs943321083 |
0.6096 | -0.554 | 0.794 | N | 0.671 | 0.356 | 0.742569787492 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/R | 23199 |
Fn3-56 |
61 | rs943321083 |
0.6096 | -0.554 | 0.794 | N | 0.671 | 0.356 | 0.742569787492 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 23199 |
Fn3-56 |
61 | rs943321083 |
0.6096 | -0.554 | 0.794 | N | 0.671 | 0.356 | 0.742569787492 | gnomAD-4.0.0 | 3.04539E-06 | None | None | None | None | N | None | 5.24366E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 23301 |
Fn3-57 |
62 | rs372799151 |
0.9716 | -1.189 | 0.805 | N | 0.531 | 0.339 | 0.466740653422 | gnomAD-2.1.1 | 2.26111E-04 | None | None | None | None | I | None | 2.60675E-03 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 23301 |
Fn3-57 |
62 | rs372799151 |
0.9716 | -1.189 | 0.805 | N | 0.531 | 0.339 | 0.466740653422 | gnomAD-3.1.2 | 7.43147E-04 | None | None | None | None | I | None | 2.65534E-03 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 9.56938E-04 |
| F/L | 23301 |
Fn3-57 |
62 | rs372799151 |
0.9716 | -1.189 | 0.805 | N | 0.531 | 0.339 | 0.466740653422 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| F/L | 23301 |
Fn3-57 |
62 | rs372799151 |
0.9716 | -1.189 | 0.805 | N | 0.531 | 0.339 | 0.466740653422 | gnomAD-4.0.0 | 1.22144E-04 | None | None | None | None | I | None | 2.5078E-03 | 3.33745E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.12079E-04 |
| Y/H | 23494 |
Fn3-58 |
60 | rs72646888 |
0.2608 | None | 0.741 | N | 0.539 | 0.291 | 0.384752662912 | gnomAD-4.0.0 | 6.84286E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09597E-06 | 0 | 1.65684E-05 |
| Y/N | 23494 |
Fn3-58 |
60 | None | 0.4723 | None | 0.484 | N | 0.615 | 0.429 | 0.683845495215 | gnomAD-4.0.0 | 6.84286E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99552E-07 | 0 | 0 |
| C/S | 23590 |
Fn3-59 |
59 | None | 0.3551 | None | 0.784 | N | 0.603 | 0.424 | 0.574465425021 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02444E-05 |
| Y/C | 23786 |
Fn3-60 |
61 | rs758011912 |
0.2105 | -1.162 | 0.997 | N | 0.585 | 0.418 | 0.53782465974 | gnomAD-2.1.1 | 8.1E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 6.59E-05 | None | 0 | 0 | 0 |
| Y/C | 23786 |
Fn3-60 |
61 | rs758011912 |
0.2105 | -1.162 | 0.997 | N | 0.585 | 0.418 | 0.53782465974 | gnomAD-4.0.0 | 3.42477E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.81058E-05 | 0 |
| Y/H | 23786 |
Fn3-60 |
61 | None | 0.7151 | None | 0.989 | N | 0.487 | 0.488 | 0.447213685739 | gnomAD-4.0.0 | 1.59516E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03232E-05 |
| Y/H | 24282 |
Fn3-64 |
61 | rs369711272 |
0.2846 | -1.316 | 0.741 | N | 0.451 | 0.384 | None | gnomAD-2.1.1 | 1.74E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.86E-05 | 2.81E-05 | 0 |
| Y/H | 24282 |
Fn3-64 |
61 | rs369711272 |
0.2846 | -1.316 | 0.741 | N | 0.451 | 0.384 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 24282 |
Fn3-64 |
61 | rs369711272 |
0.2846 | -1.316 | 0.741 | N | 0.451 | 0.384 | None | gnomAD-4.0.0 | 8.80585E-06 | None | None | None | None | N | None | 0 | 3.56544E-05 | None | 0 | 0 | None | 1.57858E-05 | 0 | 9.41473E-06 | 0 | 0 |
| Y/C | 24384 |
Fn3-65 |
62 | rs1298487582 |
0.1194 | -1.199 | 0.009 | N | 0.527 | 0.298 | 0.423480098753 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.94E-06 | 0 |
| Y/C | 24384 |
Fn3-65 |
62 | rs1298487582 |
0.1194 | -1.199 | 0.009 | N | 0.527 | 0.298 | 0.423480098753 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 24384 |
Fn3-65 |
62 | rs1298487582 |
0.1194 | -1.199 | 0.009 | N | 0.527 | 0.298 | 0.423480098753 | gnomAD-4.0.0 | 6.81924E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47805E-06 | 1.09844E-05 | 0 |
| W/C | 24578 |
Fn3-66 |
60 | rs753105114 |
0.6317 | None | 1.0 | N | 0.761 | 0.363 | 0.224531998449 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/C | 24578 |
Fn3-66 |
60 | rs753105114 |
0.6317 | None | 1.0 | N | 0.761 | 0.363 | 0.224531998449 | gnomAD-4.0.0 | 6.84538E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99875E-07 | 0 | 0 |
| W/R | 24578 |
Fn3-66 |
60 | rs1276766342 |
0.9228 | -1.582 | 0.999 | N | 0.778 | 0.485 | 0.59874208065 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| W/R | 24578 |
Fn3-66 |
60 | rs1276766342 |
0.9228 | -1.582 | 0.999 | N | 0.778 | 0.485 | 0.59874208065 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/R | 24578 |
Fn3-66 |
60 | rs1276766342 |
0.9228 | -1.582 | 0.999 | N | 0.778 | 0.485 | 0.59874208065 | gnomAD-4.0.0 | 2.56448E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.79196E-06 | 0 | 0 |
| A/V | 24674 |
Fn3-67 |
59 | rs1158950009 |
0.2518 | None | 0.663 | N | 0.449 | 0.257 | 0.414930877219 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/K | 24868 |
Fn3-68 |
61 | None | 0.9639 | None | 0.968 | N | 0.714 | 0.433 | 0.700192931172 | gnomAD-4.0.0 | 1.36884E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7992E-06 | 0 | 0 |
| I/L | 24868 |
Fn3-68 |
61 | None | 0.135 | None | 0.011 | N | 0.295 | 0.101 | 0.443388199986 | gnomAD-4.0.0 | 6.86029E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02008E-07 | 0 | 0 |
| I/R | 24868 |
Fn3-68 |
61 | None | 0.9446 | None | 0.984 | N | 0.766 | 0.48 | 0.720578909528 | gnomAD-4.0.0 | 6.84422E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99601E-07 | 0 | 0 |
| I/V | 24868 |
Fn3-68 |
61 | rs72646898 |
0.1156 | -0.804 | 0.437 | N | 0.462 | 0.071 | None | gnomAD-2.1.1 | 2.36829E-04 | None | None | None | None | N | None | 2.48201E-04 | 1.13456E-04 | None | 0 | 0 | None | 0 | None | 0 | 4.40869E-04 | 0 |
| I/V | 24868 |
Fn3-68 |
61 | rs72646898 |
0.1156 | -0.804 | 0.437 | N | 0.462 | 0.071 | None | gnomAD-3.1.2 | 2.76669E-04 | None | None | None | None | N | None | 2.65534E-04 | 3.27525E-04 | 0 | 0 | 0 | None | 0 | 0 | 3.83617E-04 | 0 | 0 |
| I/V | 24868 |
Fn3-68 |
61 | rs72646898 |
0.1156 | -0.804 | 0.437 | N | 0.462 | 0.071 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| I/V | 24868 |
Fn3-68 |
61 | rs72646898 |
0.1156 | -0.804 | 0.437 | N | 0.462 | 0.071 | None | gnomAD-4.0.0 | 4.65958E-04 | None | None | None | None | N | None | 1.7337E-04 | 1.334E-04 | None | 0 | 0 | None | 0 | 0 | 6.02683E-04 | 0 | 3.2079E-04 |
| C/S | 25264 |
Fn3-71 |
61 | rs998269154 |
0.4449 | -0.967 | 0.012 | D | 0.442 | 0.242 | 0.476986058749 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/S | 25264 |
Fn3-71 |
61 | rs998269154 |
0.4449 | -0.967 | 0.012 | D | 0.442 | 0.242 | 0.476986058749 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 25264 |
Fn3-71 |
61 | rs998269154 |
0.4449 | -0.967 | 0.012 | D | 0.442 | 0.242 | 0.476986058749 | gnomAD-4.0.0 | 1.31479E-05 | None | None | None | None | N | None | 4.82509E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 25364 |
Fn3-72 |
61 | rs1707567452 |
0.9655 | None | 0.963 | N | 0.659 | 0.48 | 0.776506168477 | gnomAD-4.0.0 | 1.59225E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| I/K | 25466 |
Fn3-73 |
62 | rs780302234 |
0.2547 | None | 0.033 | N | 0.512 | 0.236 | 0.599449292227 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/K | 25466 |
Fn3-73 |
62 | rs780302234 |
0.2547 | None | 0.033 | N | 0.512 | 0.236 | 0.599449292227 | gnomAD-4.0.0 | 6.57851E-06 | None | None | None | None | N | None | 2.41488E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 25466 |
Fn3-73 |
62 | rs780302234 |
0.1081 | -2.346 | None | N | 0.298 | 0.139 | 0.341934017632 | gnomAD-4.0.0 | 1.36887E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99572E-07 | 1.15966E-05 | 0 |
| A/G | 25756 |
Fn3-75 |
59 | None | 0.2716 | None | 0.834 | N | 0.604 | 0.287 | 0.324986149311 | gnomAD-4.0.0 | 6.84539E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99609E-07 | 0 | 0 |
| L/F | 25950 |
Fn3-76 |
61 | rs376814602 |
0.2535 | -1.01 | 0.983 | N | 0.583 | 0.172 | None | gnomAD-2.1.1 | 1.74974E-04 | None | None | None | None | N | None | 0 | 5.66E-05 | None | 0 | 2.36601E-03 | None | 0 | None | 0 | 0 | 1.40528E-04 |
| L/F | 25950 |
Fn3-76 |
61 | rs376814602 |
0.2535 | -1.01 | 0.983 | N | 0.583 | 0.172 | None | gnomAD-3.1.2 | 1.97285E-04 | None | None | None | None | N | None | 0 | 1.18048E-03 | 0 | 0 | 2.12931E-03 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| L/F | 25950 |
Fn3-76 |
61 | rs376814602 |
0.2535 | -1.01 | 0.983 | N | 0.583 | 0.172 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 3E-03 | 0 | None | None | None | 0 | None |
| L/F | 25950 |
Fn3-76 |
61 | rs376814602 |
0.2535 | -1.01 | 0.983 | N | 0.583 | 0.172 | None | gnomAD-4.0.0 | 6.44565E-05 | None | None | None | None | N | None | 0 | 3.335E-04 | None | 0 | 1.36173E-03 | None | 0 | 0 | 0 | 0 | 3.68212E-04 |
| L/I | 25950 |
Fn3-76 |
61 | None | 0.0964 | None | 0.892 | N | 0.478 | 0.219 | 0.378674557249 | gnomAD-4.0.0 | 6.84317E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99575E-07 | 0 | 0 |
| L/V | 25950 |
Fn3-76 |
61 | rs376814602 |
0.1167 | -0.603 | 0.892 | N | 0.48 | 0.171 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| L/V | 25950 |
Fn3-76 |
61 | rs376814602 |
0.1167 | -0.603 | 0.892 | N | 0.48 | 0.171 | None | gnomAD-4.0.0 | 2.05295E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69873E-06 | 0 | 0 |
| F/L | 26050 |
Fn3-77 |
61 | None | 0.8364 | None | 0.003 | N | 0.191 | 0.284 | 0.229264304666 | gnomAD-4.0.0 | 1.59192E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| F/C | 26148 |
Fn3-78 |
61 | rs956398655 |
0.9044 | None | 0.999 | N | 0.747 | 0.466 | 0.685023438539 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 26148 |
Fn3-78 |
61 | rs956398655 |
0.9044 | None | 0.999 | N | 0.747 | 0.466 | 0.685023438539 | gnomAD-4.0.0 | 5.13554E-06 | None | None | None | None | N | None | 1.69285E-05 | 0 | None | 0 | 0 | None | 0 | 2.24417E-04 | 4.79922E-06 | 0 | 0 |
| L/I | 26446 |
Fn3-80 |
61 | None | 0.148 | None | 0.811 | N | 0.52 | 0.091 | 0.165133752707 | gnomAD-4.0.0 | 6.84399E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15942E-05 | 0 |
| L/V | 26446 |
Fn3-80 |
61 | None | 0.143 | None | 0.896 | N | 0.521 | 0.087 | 0.165133752707 | gnomAD-4.0.0 | 6.84399E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5227E-05 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 26838 |
Fn3-83 |
59 | rs74365721 |
0.123 | None | 1.0 | N | 0.604 | 0.254 | 0.454987352986 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 26838 |
Fn3-83 |
59 | rs74365721 |
0.123 | None | 1.0 | N | 0.604 | 0.254 | 0.454987352986 | gnomAD-4.0.0 | 1.31543E-05 | None | None | None | None | I | None | 4.82812E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 27032 |
Fn3-84 |
61 | rs369908251 |
0.1172 | -0.691 | 0.426 | N | 0.443 | 0.116 | 0.497741790239 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| I/V | 27032 |
Fn3-84 |
61 | rs369908251 |
0.1172 | -0.691 | 0.426 | N | 0.443 | 0.116 | 0.497741790239 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 27032 |
Fn3-84 |
61 | rs369908251 |
0.1172 | -0.691 | 0.426 | N | 0.443 | 0.116 | 0.497741790239 | gnomAD-4.0.0 | 2.66493E-05 | None | None | None | None | N | None | 2.40263E-04 | 0 | None | 0 | 0 | None | 0 | 1.64636E-04 | 1.8649E-05 | 0 | 3.20246E-05 |
| Y/H | 27429 |
Fn3-87 |
61 | rs1387188018 |
0.1484 | -1.249 | 0.001 | N | 0.162 | 0.181 | 0.233150807113 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/H | 27429 |
Fn3-87 |
61 | rs1387188018 |
0.1484 | -1.249 | 0.001 | N | 0.162 | 0.181 | 0.233150807113 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/H | 27429 |
Fn3-87 |
61 | rs1387188018 |
0.1484 | -1.249 | 0.001 | N | 0.162 | 0.181 | 0.233150807113 | gnomAD-4.0.0 | 1.61129E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.20385E-05 | 0 | 0 |
| F/S | 27825 |
Fn3-90 |
60 | None | 0.5998 | None | 0.815 | N | 0.565 | 0.361 | 0.490976584422 | gnomAD-4.0.0 | 4.89272E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.89847E-05 | 0 | 0 | 0 | 6.17475E-05 |
| A/V | 27921 |
Fn3-91 |
59 | None | 0.3021 | None | 0.842 | N | 0.59 | 0.194 | 0.364342057095 | gnomAD-4.0.0 | 1.60033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86867E-06 | 0 | 0 |
| I/V | 28114 |
Fn3-92 |
60 | rs1703767853 |
0.111 | None | 0.426 | N | 0.475 | 0.11 | 0.404034981753 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 28114 |
Fn3-92 |
60 | rs1703767853 |
0.111 | None | 0.426 | N | 0.475 | 0.11 | 0.404034981753 | gnomAD-4.0.0 | 3.09873E-06 | None | None | None | None | I | None | 0 | 1.66728E-05 | None | 0 | 0 | None | 1.56255E-05 | 0 | 2.5429E-06 | 0 | 0 |
| M/L | 28214 |
Fn3-93 |
61 | None | 0.1174 | None | None | N | 0.105 | 0.178 | 0.306695030598 | gnomAD-4.0.0 | 6.84247E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15945E-05 | 0 |
| M/T | 28214 |
Fn3-93 |
61 | rs1007292303 |
0.5028 | None | 0.285 | N | 0.413 | 0.312 | 0.546393912413 | gnomAD-4.0.0 | 1.23165E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.6191E-05 | 0 | 0 |
| M/V | 28214 |
Fn3-93 |
61 | rs72648221 |
0.1411 | -1.124 | 0.036 | N | 0.345 | 0.2 | None | gnomAD-2.1.1 | 2.39253E-04 | None | None | None | None | I | None | 2.47934E-04 | 1.13205E-04 | None | 0 | 0 | None | 0 | None | 0 | 4.45278E-04 | 0 |
| M/V | 28214 |
Fn3-93 |
61 | rs72648221 |
0.1411 | -1.124 | 0.036 | N | 0.345 | 0.2 | None | gnomAD-3.1.2 | 3.02254E-04 | None | None | None | None | I | None | 2.65303E-04 | 3.27354E-04 | 0 | 0 | 0 | None | 0 | 0 | 4.11571E-04 | 4.14079E-04 | 0 |
| M/V | 28214 |
Fn3-93 |
61 | rs72648221 |
0.1411 | -1.124 | 0.036 | N | 0.345 | 0.2 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| M/V | 28214 |
Fn3-93 |
61 | rs72648221 |
0.1411 | -1.124 | 0.036 | N | 0.345 | 0.2 | None | gnomAD-4.0.0 | 4.67849E-04 | None | None | None | None | I | None | 1.73213E-04 | 1.33307E-04 | None | 0 | 0 | None | 0 | 0 | 6.02668E-04 | 3.29402E-05 | 3.20113E-04 |
| F/C | 28312 |
Fn3-94 |
61 | rs1703534719 |
0.7241 | None | 0.997 | N | 0.755 | 0.419 | 0.668570387503 | gnomAD-4.0.0 | 1.59178E-06 | None | None | None | None | N | None | 0 | 2.28697E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 28510 |
Fn3-95 |
61 | None | 0.266 | None | 1.0 | N | 0.855 | 0.454 | 0.652629836549 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| Y/C | 28710 |
Fn3-97 |
60 | None | 0.1771 | None | 0.009 | N | 0.486 | 0.3 | 0.314417295294 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| H/Q | 29000 |
Fn3-99 |
59 | rs758683372 |
0.2117 | None | 0.907 | N | 0.475 | 0.303 | 0.176091768786 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| H/Q | 29000 |
Fn3-99 |
59 | rs758683372 |
0.2117 | None | 0.907 | N | 0.475 | 0.303 | 0.176091768786 | gnomAD-4.0.0 | 6.57358E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| M/R | 29197 |
Fn3-100 |
61 | None | 0.6913 | None | 0.106 | N | 0.529 | 0.317 | 0.626322489162 | gnomAD-4.0.0 | 1.59104E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85783E-06 | 0 | 0 |
| M/T | 29197 |
Fn3-100 |
61 | None | 0.4905 | None | None | N | 0.327 | 0.324 | 0.60311569301 | gnomAD-4.0.0 | 1.59104E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| F/L | 29297 |
Fn3-101 |
61 | rs755953829 |
0.8543 | -1.207 | 0.011 | N | 0.217 | 0.24 | 0.28058544554 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | I | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 29297 |
Fn3-101 |
61 | rs755953829 |
0.8543 | -1.207 | 0.011 | N | 0.217 | 0.24 | 0.28058544554 | gnomAD-4.0.0 | 3.18195E-06 | None | None | None | None | I | None | 0 | 4.57247E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/Y | 29297 |
Fn3-101 |
61 | rs373621460 |
0.1571 | -0.414 | 0.103 | N | 0.375 | 0.151 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| F/Y | 29297 |
Fn3-101 |
61 | rs373621460 |
0.1571 | -0.414 | 0.103 | N | 0.375 | 0.151 | None | gnomAD-4.0.0 | 1.59098E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85771E-06 | 0 | 0 |
| F/L | 29395 |
Fn3-102 |
61 | rs55940667 |
0.9275 | -0.97 | 0.008 | N | 0.287 | 0.219 | 0.226586394389 | gnomAD-2.1.1 | 1.39264E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.90604E-03 | None | 6.54E-05 | None | 0 | 0 | 0 |
| F/L | 29395 |
Fn3-102 |
61 | rs55940667 |
0.9275 | -0.97 | 0.008 | N | 0.287 | 0.219 | 0.226586394389 | gnomAD-3.1.2 | 9.86E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 2.69749E-03 | None | 0 | 0 | 0 | 2.06954E-04 | 0 |
| F/L | 29395 |
Fn3-102 |
61 | rs55940667 |
0.9275 | -0.97 | 0.008 | N | 0.287 | 0.219 | 0.226586394389 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 2E-03 | 0 | None | None | None | 0 | None |
| F/L | 29395 |
Fn3-102 |
61 | rs55940667 |
0.9275 | -0.97 | 0.008 | N | 0.287 | 0.219 | 0.226586394389 | gnomAD-4.0.0 | 3.65591E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.0492E-03 | None | 0 | 0 | 0 | 4.39174E-05 | 1.28057E-04 |
| I/L | 29593 |
Fn3-103 |
61 | rs1412856815 |
0.0982 | -0.091 | None | N | 0.159 | 0.06 | 0.210429274316 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| I/L | 29593 |
Fn3-103 |
61 | rs1412856815 |
0.0982 | -0.091 | None | N | 0.159 | 0.06 | 0.210429274316 | gnomAD-4.0.0 | 1.36834E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79885E-06 | 0 | 0 |
| I/T | 29593 |
Fn3-103 |
61 | None | 0.2612 | None | 0.062 | N | 0.485 | 0.304 | 0.566408210792 | gnomAD-4.0.0 | 3.18212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85781E-06 | 1.43271E-05 | 0 |
| Q/H | 29693 |
Fn3-104 |
61 | rs778478943 |
0.2912 | -0.64 | 0.002 | N | 0.365 | 0.125 | 0.0806252709748 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Q/H | 29693 |
Fn3-104 |
61 | rs778478943 |
0.2912 | -0.64 | 0.002 | N | 0.365 | 0.125 | 0.0806252709748 | gnomAD-4.0.0 | 4.77395E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57383E-06 | 0 | 0 |
| I/M | 30088 |
Fn3-107 |
59 | rs1238844529 |
0.0541 | None | 0.927 | N | 0.458 | 0.136 | 0.351830644314 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/M | 30088 |
Fn3-107 |
59 | rs1238844529 |
0.0541 | None | 0.927 | N | 0.458 | 0.136 | 0.351830644314 | gnomAD-4.0.0 | 6.57212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46994E-05 | 0 | 0 |
| I/T | 30088 |
Fn3-107 |
59 | None | 0.1187 | None | 0.425 | N | 0.419 | 0.226 | 0.456647468687 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| F/L | 30780 |
Fn3-112 |
62 | rs1698389479 |
0.7787 | None | 0.09 | N | 0.421 | 0.171 | 0.325263233342 | gnomAD-4.0.0 | 1.36834E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99421E-07 | 0 | 1.6564E-05 |
| F/I | 31075 |
Fn3-114 |
60 | rs956327300 |
0.1037 | -0.818 | None | N | 0.113 | 0.079 | 0.286848849266 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 1.17924E-03 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/I | 31075 |
Fn3-114 |
60 | rs956327300 |
0.1037 | -0.818 | None | N | 0.113 | 0.079 | 0.286848849266 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/I | 31075 |
Fn3-114 |
60 | rs956327300 |
0.1037 | -0.818 | None | N | 0.113 | 0.079 | 0.286848849266 | gnomAD-4.0.0 | 6.57237E-06 | None | None | None | None | N | None | 0 | 6.55222E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 31075 |
Fn3-114 |
60 | rs956327300 |
0.199 | -0.82 | None | N | 0.101 | 0.072 | 0.433157607263 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
| F/L | 31075 |
Fn3-114 |
60 | rs956327300 |
0.199 | -0.82 | None | N | 0.101 | 0.072 | 0.433157607263 | gnomAD-4.0.0 | 1.02628E-05 | None | None | None | None | N | None | 2.98721E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.16929E-05 | 0 | 1.6564E-05 |
| F/C | 31171 |
Fn3-115 |
59 | rs759179376 |
0.1646 | -1.212 | 0.946 | N | 0.596 | 0.31 | 0.606262950116 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| F/C | 31171 |
Fn3-115 |
59 | rs759179376 |
0.1646 | -1.212 | 0.946 | N | 0.596 | 0.31 | 0.606262950116 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/C | 31171 |
Fn3-115 |
59 | rs759179376 |
0.1646 | -1.212 | 0.946 | N | 0.596 | 0.31 | 0.606262950116 | gnomAD-4.0.0 | 1.85902E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.5428E-06 | 0 | 0 |
| F/L | 31171 |
Fn3-115 |
59 | None | 0.6612 | None | None | N | 0.177 | 0.177 | 0.181679512989 | gnomAD-4.0.0 | 3.18218E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 2.85806E-06 | 0 | 0 |
| I/S | 31368 |
Fn3-116 |
61 | None | 0.891 | None | 0.999 | N | 0.649 | 0.472 | 0.723900465636 | gnomAD-4.0.0 | 2.40068E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62504E-06 | 0 | 0 |
| Y/C | 31468 |
Fn3-117 |
61 | None | 0.1517 | None | 0.993 | N | 0.686 | 0.367 | 0.514866526686 | gnomAD-4.0.0 | 4.10523E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 5.20291E-04 | 2.69843E-06 | 0 | 0 |
| F/L | 31569 |
Fn3-118 |
64 | None | 0.9944 | None | 0.999 | N | 0.589 | 0.455 | 0.36036328697 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 31767 |
Fn3-119 |
60 | rs1431446089 |
0.0456 | -1.294 | None | N | 0.396 | 0.233 | 0.345859378078 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| Y/C | 31767 |
Fn3-119 |
60 | rs1431446089 |
0.0456 | -1.294 | None | N | 0.396 | 0.233 | 0.345859378078 | gnomAD-4.0.0 | 4.77354E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57456E-06 | 0 | 0 |
| L/M | 31868 |
Fn3-120 |
62 | None | 0.1203 | None | 0.996 | N | 0.797 | 0.299 | 0.509053020717 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/Q | 31868 |
Fn3-120 |
62 | rs1559138758 |
0.4305 | None | 0.996 | N | 0.817 | 0.516 | 0.78423951252 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
| L/Q | 31868 |
Fn3-120 |
62 | rs1559138758 |
0.4305 | None | 0.996 | N | 0.817 | 0.516 | 0.78423951252 | gnomAD-4.0.0 | 1.59163E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77285E-05 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 31970 |
Fn3-121 |
62 | None | 0.8993 | None | 0.978 | N | 0.498 | 0.405 | 0.317084106153 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/H | 32164 |
Fn3-122 |
60 | rs1374040247 |
0.2494 | -1.343 | 0.99 | N | 0.545 | 0.491 | 0.390531646278 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| Y/H | 32164 |
Fn3-122 |
60 | rs1374040247 |
0.2494 | -1.343 | 0.99 | N | 0.545 | 0.491 | 0.390531646278 | gnomAD-4.0.0 | 3.18287E-06 | None | None | None | None | N | None | 0 | 2.28697E-05 | None | 0 | 0 | None | 0 | 0 | 2.85837E-06 | 0 | 0 |
| H/N | 32262 |
Fn3-123 |
61 | rs1376767409 |
0.2251 | -2.122 | 0.961 | N | 0.466 | 0.318 | 0.297718772494 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| H/N | 32262 |
Fn3-123 |
61 | rs1376767409 |
0.2251 | -2.122 | 0.961 | N | 0.466 | 0.318 | 0.297718772494 | gnomAD-4.0.0 | 2.05265E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69843E-06 | 0 | 0 |
| H/Y | 32262 |
Fn3-123 |
61 | None | 0.0855 | None | 0.012 | N | 0.243 | 0.273 | 0.180583059064 | gnomAD-4.0.0 | 6.84217E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65656E-05 |
| F/I | 32459 |
Fn3-124 |
61 | rs56009327 |
0.6227 | None | 0.982 | N | 0.442 | 0.467 | 0.443285836454 | gnomAD-4.0.0 | 1.8475E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.42869E-05 | 0 | 0 |
| F/V | 32459 |
Fn3-124 |
61 | None | 0.5826 | None | 0.939 | N | 0.482 | 0.386 | 0.550885202691 | gnomAD-4.0.0 | 6.84258E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99514E-07 | 0 | 0 |
| Y/C | 32559 |
Fn3-125 |
61 | None | 0.3177 | None | 1.0 | N | 0.776 | 0.488 | 0.574195325796 | gnomAD-4.0.0 | 1.59428E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77994E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 32660 |
Fn3-126 |
61 | rs781416687 |
0.9319 | -1.105 | 1.0 | N | 0.749 | 0.504 | 0.512766428439 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/H | 32660 |
Fn3-126 |
61 | rs781416687 |
0.9319 | -1.105 | 1.0 | N | 0.749 | 0.504 | 0.512766428439 | gnomAD-4.0.0 | 6.58137E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47115E-05 | 0 | 0 |
| L/P | 32855 |
Fn3-127 |
61 | rs772942895 |
0.975 | -0.907 | 1.0 | N | 0.883 | 0.683 | 0.849913666397 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65399E-04 |
| L/P | 32855 |
Fn3-127 |
61 | rs772942895 |
0.975 | -0.907 | 1.0 | N | 0.883 | 0.683 | 0.849913666397 | gnomAD-4.0.0 | 6.15782E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59794E-06 | 4.63736E-05 | 1.65651E-05 |
| Y/C | 32957 |
Fn3-128 |
62 | rs545990990 |
0.498 | -1.484 | 1.0 | N | 0.791 | 0.434 | 0.594452868026 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 32957 |
Fn3-128 |
62 | rs545990990 |
0.498 | -1.484 | 1.0 | N | 0.791 | 0.434 | 0.594452868026 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| Y/C | 32957 |
Fn3-128 |
62 | rs545990990 |
0.498 | -1.484 | 1.0 | N | 0.791 | 0.434 | 0.594452868026 | gnomAD-4.0.0 | 6.56814E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93424E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 32957 |
Fn3-128 |
62 | rs1267513093 |
0.7271 | -1.49 | 1.0 | N | 0.751 | 0.536 | 0.499281839539 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| Y/H | 32957 |
Fn3-128 |
62 | rs1267513093 |
0.7271 | -1.49 | 1.0 | N | 0.751 | 0.536 | 0.499281839539 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/H | 32957 |
Fn3-128 |
62 | rs1267513093 |
0.7271 | -1.49 | 1.0 | N | 0.751 | 0.536 | 0.499281839539 | gnomAD-4.0.0 | 6.57341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4702E-05 | 0 | 0 |
| Y/N | 32957 |
Fn3-128 |
62 | None | 0.8885 | None | 1.0 | N | 0.795 | 0.613 | 0.827634584912 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 33351 |
Fn3-130 |
62 | None | 0.7296 | None | 0.999 | N | 0.726 | 0.425 | 0.662473173981 | gnomAD-4.0.0 | 1.59303E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86067E-06 | 0 | 0 |
| F/S | 33452 |
Fn3-131 |
61 | rs1450640139 |
0.7307 | -0.959 | 0.549 | N | 0.548 | 0.29 | 0.63141776442 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| F/S | 33452 |
Fn3-131 |
61 | rs1450640139 |
0.7307 | -0.959 | 0.549 | N | 0.548 | 0.29 | 0.63141776442 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/S | 33452 |
Fn3-131 |
61 | rs1450640139 |
0.7307 | -0.959 | 0.549 | N | 0.548 | 0.29 | 0.63141776442 | gnomAD-4.0.0 | 6.57022E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46994E-05 | 0 | 0 |
| Y/C | 33747 |
Fn3-132 |
59 | None | 0.3766 | None | 1.0 | N | 0.672 | 0.447 | 0.55025283692 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/H | 33747 |
Fn3-132 |
59 | rs1310463317 |
0.6811 | -1.088 | 0.998 | D | 0.505 | 0.466 | 0.387529464389 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/H | 33747 |
Fn3-132 |
59 | rs1310463317 |
0.6811 | -1.088 | 0.998 | D | 0.505 | 0.466 | 0.387529464389 | gnomAD-4.0.0 | 1.59108E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.