Structural position:

  • Domain Type: Fn3
  • Aligned Position: 99
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
K/R 15723 Fn3-1 67 rs2057715789 0.0952 None 0.997 N 0.379 0.204 0.314716216878 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/R 15723 Fn3-1 67 rs2057715789 0.0952 None 0.997 N 0.379 0.204 0.314716216878 gnomAD-4.0.0 2.03042E-06 None None None None N None 0 0 None 0 0 None 0 0 2.4102E-06 0 0
E/K 15825 Fn3-2 68 None 0.5939 None 0.999 D 0.685 0.321 0.471539375507 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/R 15926 Fn3-3 68 None 0.0972 None 0.025 N 0.32 0.093 0.366466682447 gnomAD-4.0.0 1.20188E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31421E-06 0 0
Q/E 16121 Fn3-4 67 rs779364355 0.0794 -0.178 0.021 N 0.101 0.152 0.200317383148 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 1.68577E-04 None 0 None 0 0 0
Q/E 16121 Fn3-4 67 rs779364355 0.0794 -0.178 0.021 N 0.101 0.152 0.200317383148 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 1.95008E-04 None 0 0 0 0 0
Q/E 16121 Fn3-4 67 rs779364355 0.0794 -0.178 0.021 N 0.101 0.152 0.200317383148 gnomAD-4.0.0 1.79758E-05 None None None None N None 0 0 None 0 3.1678E-04 None 0 0 0 0 2.85063E-05
Q/H 16121 Fn3-4 67 None 0.2373 None 0.996 N 0.407 0.303 0.328752806141 gnomAD-4.0.0 1.59477E-06 None None None None N None 0 0 None 0 2.78458E-05 None 0 0 0 0 0
E/D 16221 Fn3-5 67 rs2057034517 0.2971 None 0.994 D 0.536 0.263 0.322786055943 gnomAD-4.0.0 1.6324E-06 None None None None N None 0 0 None 0 0 None 0 0 2.92767E-06 0 0
E/K 16221 Fn3-5 67 None 0.1589 None 0.994 N 0.615 0.314 0.491455083755 gnomAD-4.0.0 1.38346E-06 None None None None N None 6.01685E-05 0 None 0 0 None 0 0 0 0 0
P/R 16417 Fn3-6 67 rs1387631926 0.3558 -0.593 0.852 D 0.475 0.49 0.593114555169 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/R 16417 Fn3-6 67 rs1387631926 0.3558 -0.593 0.852 D 0.475 0.49 0.593114555169 gnomAD-4.0.0 1.59407E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43361E-05 0
P/S 16417 Fn3-6 67 None 0.1841 None 0.852 D 0.335 0.41 0.344017737713 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
N/D 16517 Fn3-7 68 rs1052305609 0.4774 -0.21 0.98 N 0.417 0.279 0.34854441366 gnomAD-2.1.1 4.09E-06 None None None None N None 0 2.94E-05 None 0 0 None 0 None 0 0 0
N/D 16517 Fn3-7 68 rs1052305609 0.4774 -0.21 0.98 N 0.417 0.279 0.34854441366 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/D 16517 Fn3-7 68 rs1052305609 0.4774 -0.21 0.98 N 0.417 0.279 0.34854441366 gnomAD-4.0.0 2.57504E-06 None None None None N None 0 1.70596E-05 None 0 0 None 0 0 2.40134E-06 0 0
E/K 16617 Fn3-8 67 None 0.5053 None 0.998 D 0.556 0.308 0.383921772103 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/D 16717 Fn3-9 67 rs369623681 0.2738 -0.52 0.434 D 0.206 0.157 0.227260227426 gnomAD-2.1.1 1.08E-05 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 1.57E-05 0
E/D 16717 Fn3-9 67 rs369623681 0.2738 -0.52 0.434 D 0.206 0.157 0.227260227426 gnomAD-3.1.2 1.97E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 2.94E-05 0 0
E/D 16717 Fn3-9 67 rs369623681 0.2738 -0.52 0.434 D 0.206 0.157 0.227260227426 gnomAD-4.0.0 2.17067E-05 None None None None N None 1.33679E-05 0 None 0 0 None 0 0 2.54409E-05 4.3929E-05 0
E/K 16818 Fn3-10 68 rs397517600 0.7033 -0.118 1.0 D 0.693 0.417 0.426551566703 gnomAD-2.1.1 2.57904E-04 None None None None N None 0 8.5E-05 None 4.74806E-03 0 None 0 None 0 1.17762E-04 7.04027E-04
E/K 16818 Fn3-10 68 rs397517600 0.7033 -0.118 1.0 D 0.693 0.417 0.426551566703 gnomAD-3.1.2 1.24993E-04 None None None None N None 0 0 0 4.03226E-03 0 None 0 0 4.42E-05 0 9.56023E-04
E/K 16818 Fn3-10 68 rs397517600 0.7033 -0.118 1.0 D 0.693 0.417 0.426551566703 gnomAD-4.0.0 1.22768E-04 None None None None N None 0 6.67445E-05 None 4.32725E-03 0 None 0 1.64799E-04 3.39192E-05 0 4.00564E-04
P/A 16920 Fn3-11 69 rs377289817 0.1096 -1.099 1.0 D 0.727 0.447 None gnomAD-2.1.1 2.44079E-04 None None None None N None 2.40225E-03 2.83302E-04 None 0 0 None 0 None 0 0 0
P/A 16920 Fn3-11 69 rs377289817 0.1096 -1.099 1.0 D 0.727 0.447 None gnomAD-3.1.2 5.85711E-04 None None None None N None 2.02791E-03 1.96773E-04 0 0 0 None 0 0 0 0 9.56023E-04
P/A 16920 Fn3-11 69 rs377289817 0.1096 -1.099 1.0 D 0.727 0.447 None 1000 genomes 5.99042E-04 None None None None N None 2.3E-03 0 None None 0 0 None None None 0 None
P/A 16920 Fn3-11 69 rs377289817 0.1096 -1.099 1.0 D 0.727 0.447 None gnomAD-4.0.0 1.00438E-04 None None None None N None 1.84098E-03 2.83532E-04 None 0 0 None 0 0 0 0 1.12126E-04
P/L 17113 Fn3-12 67 rs763635220 0.2941 None 0.998 D 0.746 0.54 0.639464360942 gnomAD-4.0.0 1.5928E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86151E-06 0 0
P/Q 17113 Fn3-12 67 rs763635220 0.3547 None 0.962 N 0.383 0.457 0.399304321381 gnomAD-4.0.0 3.18561E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72302E-06 0 0
P/S 17113 Fn3-12 67 rs768641489 0.2957 -0.821 0.998 N 0.729 0.549 0.418221603839 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 1.78E-05 0
P/S 17113 Fn3-12 67 rs768641489 0.2957 -0.821 0.998 N 0.729 0.549 0.418221603839 gnomAD-4.0.0 2.22991E-05 None None None None N None 0 4.57519E-05 None 0 0 None 3.76492E-05 0 1.14458E-05 4.29947E-05 9.0854E-05
E/D 17214 Fn3-13 68 rs372443762 0.3927 -0.397 0.996 N 0.524 0.297 0.330331372229 gnomAD-2.1.1 2.86E-05 None None None None N None 2.89855E-04 0 None 0 0 None 0 None 0 0 1.40371E-04
E/D 17214 Fn3-13 68 rs372443762 0.3927 -0.397 0.996 N 0.524 0.297 0.330331372229 gnomAD-3.1.2 7.24E-05 None None None None N None 2.41581E-04 6.57E-05 0 0 0 None 0 0 0 0 0
E/D 17214 Fn3-13 68 rs372443762 0.3927 -0.397 0.996 N 0.524 0.297 0.330331372229 gnomAD-4.0.0 6.8453E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99847E-07 0 0
E/K 17214 Fn3-13 68 rs769926361 0.173 0.304 0.992 N 0.599 0.306 0.485705203746 gnomAD-4.0.0 3.42257E-06 None None None None N None 0 0 None 0 0 None 0 0 0 5.80033E-05 0
E/G 17536 Fn3-15 67 rs776023005 0.6605 -0.945 1.0 N 0.577 0.518 0.475506082792 gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.98E-06 0
E/G 17536 Fn3-15 67 rs776023005 0.6605 -0.945 1.0 N 0.577 0.518 0.475506082792 gnomAD-4.0.0 1.59565E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86451E-06 0 0
E/D 17636 Fn3-16 68 rs748175453 0.398 -0.417 0.999 N 0.6 0.287 0.40722173914 gnomAD-2.1.1 8.22E-05 None None None None N None 0 0 None 0 1.18863E-03 None 0 None 0 0 0
E/D 17636 Fn3-16 68 rs748175453 0.398 -0.417 0.999 N 0.6 0.287 0.40722173914 gnomAD-3.1.2 4.61E-05 None None None None N None 0 6.56E-05 0 0 1.16686E-03 None 0 0 0 0 0
E/D 17636 Fn3-16 68 rs748175453 0.398 -0.417 0.999 N 0.6 0.287 0.40722173914 gnomAD-4.0.0 1.98384E-05 None None None None N None 0 1.66783E-05 None 0 6.70961E-04 None 0 0 0 0 1.60169E-05
E/K 17829 Fn3-17 66 rs1460605461 0.7796 -0.709 0.998 N 0.517 0.336 0.413113201963 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
E/K 17829 Fn3-17 66 rs1460605461 0.7796 -0.709 0.998 N 0.517 0.336 0.413113201963 gnomAD-4.0.0 1.59338E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86208E-06 0 0
E/V 17829 Fn3-17 66 rs764618019 0.7114 -0.38 0.999 N 0.616 0.394 0.530803083455 gnomAD-2.1.1 7.16E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.57E-05 0
E/V 17829 Fn3-17 66 rs764618019 0.7114 -0.38 0.999 N 0.616 0.394 0.530803083455 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/V 17829 Fn3-17 66 rs764618019 0.7114 -0.38 0.999 N 0.616 0.394 0.530803083455 gnomAD-4.0.0 2.48033E-06 None None None None N None 0 0 None 0 0 None 0 0 3.392E-06 0 0
E/G 17929 Fn3-18 68 None 0.457 None 0.999 N 0.617 0.541 0.472023113445 gnomAD-4.0.0 1.59432E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86462E-06 0 0
E/K 17929 Fn3-18 68 rs201052994 0.5178 -0.245 0.998 D 0.641 0.354 0.338110398507 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
E/K 17929 Fn3-18 68 rs201052994 0.5178 -0.245 0.998 D 0.641 0.354 0.338110398507 gnomAD-3.1.2 1.98E-05 None None None None N None 0 0 0 0 0 None 0 0 4.42E-05 0 0
E/K 17929 Fn3-18 68 rs201052994 0.5178 -0.245 0.998 D 0.641 0.354 0.338110398507 gnomAD-4.0.0 1.0544E-05 None None None None N None 0 0 None 0 0 None 0 0 1.44203E-05 0 0
P/L 18133 Fn3-19 69 None 0.2398 None 0.669 N 0.413 0.435 0.577797438266 gnomAD-4.0.0 2.08359E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.78673E-05
P/S 18133 Fn3-19 69 rs532354607 0.1875 None 0.454 N 0.346 0.27 0.301789629655 gnomAD-4.0.0 2.10634E-06 None None None None N None 0 0 None 0 0 None 0 0 3.66666E-06 0 0
E/Q 18238 Fn3-20 73 None 0.2619 None 0.999 N 0.676 0.416 0.411133732114 gnomAD-4.0.0 1.59345E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43402E-05 0
E/G 18651 Fn3-23 73 rs876658067 0.2812 -1.164 0.014 N 0.279 0.268 0.331365685468 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
E/G 18651 Fn3-23 73 rs876658067 0.2812 -1.164 0.014 N 0.279 0.268 0.331365685468 gnomAD-4.0.0 8.214E-06 None None None None N None 0 0 None 0 0 None 0 0 7.19837E-06 0 6.62888E-05
E/K 18651 Fn3-23 73 None 0.2692 None 0.822 N 0.574 0.304 0.370240404367 gnomAD-4.0.0 1.59289E-06 None None None None N None 5.66829E-05 0 None 0 0 None 0 0 0 0 0
E/D 18851 Fn3-24 68 None 0.2488 None 0.963 N 0.529 0.251 0.301455362545 gnomAD-4.0.0 1.75616E-06 None None None None N None 0 0 None 0 0 None 1.94977E-05 0 0 0 0
E/Q 18851 Fn3-24 68 rs1347369638 0.1638 None 0.989 N 0.653 0.283 0.254244900254 gnomAD-4.0.0 7.12769E-07 None None None None N None 3.20718E-05 0 None 0 0 None 0 0 0 0 0
E/D 19055 Fn3-26 68 rs1263660973 0.2064 -0.271 0.998 N 0.545 0.27 0.344017737713 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
E/D 19055 Fn3-26 68 rs1263660973 0.2064 -0.271 0.998 N 0.545 0.27 0.344017737713 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
E/D 19055 Fn3-26 68 rs1263660973 0.2064 -0.271 0.998 N 0.545 0.27 0.344017737713 gnomAD-4.0.0 6.84367E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99616E-07 0 0
E/Q 19055 Fn3-26 68 None 0.1641 None 1.0 N 0.669 0.321 0.346315397577 gnomAD-4.0.0 1.59217E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85982E-06 0 0
Q/P 19250 Fn3-27 68 None 0.0757 None 0.106 N 0.393 0.194 0.165133752707 gnomAD-4.0.0 6.93904E-06 None None None None N None 0 0 None 0 0 None 0 0 9.08471E-06 0 0
E/D 19351 Fn3-28 68 None 0.4458 None 0.006 N 0.096 0.161 0.255777322467 gnomAD-4.0.0 3.18562E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.87051E-05 0
E/Q 19546 Fn3-29 68 rs201840554 0.2461 -0.224 1.0 N 0.673 0.354 None gnomAD-2.1.1 9.91836E-04 None None None None N None 1.0508E-02 3.12181E-04 None 0 0 None 0 None 0 4.7E-05 8.44832E-04
E/Q 19546 Fn3-29 68 rs201840554 0.2461 -0.224 1.0 N 0.673 0.354 None gnomAD-3.1.2 2.93355E-03 None None None None N None 1.04313E-02 3.93494E-04 0 0 0 None 0 0 8.83E-05 0 9.5511E-04
E/Q 19546 Fn3-29 68 rs201840554 0.2461 -0.224 1.0 N 0.673 0.354 None 1000 genomes 2.19649E-03 None None None None N None 8.3E-03 0 None None 0 0 None None None 0 None
E/Q 19546 Fn3-29 68 rs201840554 0.2461 -0.224 1.0 N 0.673 0.354 None gnomAD-4.0.0 5.47979E-04 None None None None N None 1.08272E-02 3.83794E-04 None 0 0 None 0 3.30469E-04 9.32537E-06 3.29468E-05 5.28372E-04
E/Q 19646 Fn3-30 68 None 0.2721 None 0.489 N 0.235 0.266 0.247872288689 gnomAD-4.0.0 1.59197E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85945E-06 0 0
D/G 19749 Fn3-31 70 rs1414991035 0.1532 -0.83 0.896 N 0.393 0.294 0.338834610459 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
D/G 19749 Fn3-31 70 rs1414991035 0.1532 -0.83 0.896 N 0.393 0.294 0.338834610459 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94175E-04 None 0 0 0 0 0
D/G 19749 Fn3-31 70 rs1414991035 0.1532 -0.83 0.896 N 0.393 0.294 0.338834610459 gnomAD-4.0.0 2.56316E-06 None None None None N None 0 0 None 0 4.85625E-05 None 0 0 0 0 0
D/N 19749 Fn3-31 70 rs2050531286 0.0979 None 0.103 N 0.216 0.234 0.241078983079 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
D/N 19749 Fn3-31 70 rs2050531286 0.0979 None 0.103 N 0.216 0.234 0.241078983079 gnomAD-4.0.0 6.57566E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07039E-04 0
E/K 19943 Fn3-32 67 rs751863629 0.2535 -0.187 0.999 N 0.702 0.418 0.472344434578 gnomAD-2.1.1 2.42E-05 None None None None N None 0 1.74561E-04 None 0 0 None 0 None 0 0 0
E/K 19943 Fn3-32 67 rs751863629 0.2535 -0.187 0.999 N 0.702 0.418 0.472344434578 gnomAD-4.0.0 1.75228E-05 None None None None N None 0 2.51935E-04 None 0 0 None 0 0 0 0 0
Q/H 20042 Fn3-33 66 None 0.2869 None 0.006 N 0.189 0.136 0.321951552304 gnomAD-4.0.0 1.59198E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43316E-05 0
K/R 20238 Fn3-34 68 None 0.0927 None 0.121 N 0.274 0.14 0.310147130316 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 20439 Fn3-36 69 rs778185086 0.4394 -0.179 0.999 N 0.669 0.393 0.526181570707 gnomAD-2.1.1 4.12E-06 None None None None N None 0 0 None 0 0 None 3.45E-05 None 0 0 0
E/K 20439 Fn3-36 69 rs778185086 0.4394 -0.179 0.999 N 0.669 0.393 0.526181570707 gnomAD-4.0.0 1.60469E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.46327E-05 0
E/G 20735 Fn3-38 68 rs767027188 0.8082 -1.191 1.0 N 0.584 0.558 0.469660041277 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.62E-05 None 0 None 0 0 0
E/G 20735 Fn3-38 68 rs767027188 0.8082 -1.191 1.0 N 0.584 0.558 0.469660041277 gnomAD-4.0.0 1.59219E-06 None None None None N None 0 0 None 0 2.78334E-05 None 0 0 0 0 0
P/L 21030 Fn3-40 68 rs886042482 0.2154 None 1.0 N 0.761 0.513 0.827809084627 gnomAD-4.0.0 6.87713E-07 None None None None N None 0 0 None 0 0 None 0 0 9.01938E-07 0 0
P/Q 21030 Fn3-40 68 rs886042482 0.2422 -0.819 1.0 N 0.777 0.469 0.662738656811 gnomAD-2.1.1 1.24E-05 None None None None N None 0 8.96E-05 None 0 0 None 0 None 0 0 0
P/Q 21030 Fn3-40 68 rs886042482 0.2422 -0.819 1.0 N 0.777 0.469 0.662738656811 gnomAD-4.0.0 2.06314E-06 None None None None N None 0 6.86593E-05 None 0 0 None 0 0 0 0 0
P/R 21030 Fn3-40 68 None 0.3021 None 1.0 N 0.773 0.532 0.751018391696 gnomAD-4.0.0 1.37543E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80388E-06 0 0
P/L 21332 Fn3-42 67 None 0.236 None 0.942 N 0.637 0.553 0.622959606287 gnomAD-4.0.0 1.59227E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86049E-06 0 0
P/S 21332 Fn3-42 67 None 0.2191 None 0.126 N 0.293 0.437 0.270447802918 gnomAD-4.0.0 1.3688E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99682E-07 0 1.65733E-05
P/T 21332 Fn3-42 67 rs879031561 0.1788 -0.88 0.698 N 0.491 0.511 None gnomAD-2.1.1 1.21E-05 None None None None N None 1.93849E-04 0 None 0 0 None 0 None 0 0 0
P/T 21332 Fn3-42 67 rs879031561 0.1788 -0.88 0.698 N 0.491 0.511 None gnomAD-3.1.2 3.95E-05 None None None None N None 1.44921E-04 0 0 0 0 None 0 0 0 0 0
P/T 21332 Fn3-42 67 rs879031561 0.1788 -0.88 0.698 N 0.491 0.511 None gnomAD-4.0.0 1.11587E-05 None None None None N None 1.60351E-04 0 None 0 0 None 0 0 0 1.09806E-05 8.00974E-05
P/L 21626 Fn3-44 68 None 0.1611 None 0.961 N 0.547 0.514 0.611689863146 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/T 21626 Fn3-44 68 rs2048562251 0.1046 None 0.248 N 0.262 0.327 0.335661160332 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
P/T 21626 Fn3-44 68 rs2048562251 0.1046 None 0.248 N 0.262 0.327 0.335661160332 gnomAD-4.0.0 6.57739E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07125E-04 0
E/K 21826 Fn3-46 70 rs763824247 0.3448 -0.65 0.999 N 0.683 0.325 0.460526725402 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
E/K 21826 Fn3-46 70 rs763824247 0.3448 -0.65 0.999 N 0.683 0.325 0.460526725402 gnomAD-4.0.0 3.18899E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72505E-06 0 0
E/K 22122 Fn3-48 68 rs764747244 0.4438 0.522 0.919 N 0.563 0.295 0.37568098594 gnomAD-2.1.1 8.05E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
E/K 22122 Fn3-48 68 rs764747244 0.4438 0.522 0.919 N 0.563 0.295 0.37568098594 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
E/K 22122 Fn3-48 68 rs764747244 0.4438 0.522 0.919 N 0.563 0.295 0.37568098594 gnomAD-4.0.0 1.0538E-05 None None None None N None 0 5.00334E-05 None 0 2.23294E-05 None 0 0 1.01737E-05 0 1.60174E-05
E/Q 22122 Fn3-48 68 rs764747244 0.3411 None 0.414 N 0.303 0.217 0.343334270461 gnomAD-4.0.0 6.84386E-07 None None None None N None 0 0 None 0 0 None 0 1.73671E-04 0 0 0
E/K 22224 Fn3-49 69 None 0.2588 None 0.978 N 0.535 0.321 0.467669411796 gnomAD-4.0.0 1.59364E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.03049E-05
E/G 22420 Fn3-50 67 rs1356121178 0.3913 -0.747 0.704 N 0.394 0.324 0.354822389136 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
E/G 22420 Fn3-50 67 rs1356121178 0.3913 -0.747 0.704 N 0.394 0.324 0.354822389136 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
E/K 22420 Fn3-50 67 rs530426755 0.3691 0.514 0.92 N 0.434 0.293 0.264081493735 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94099E-04 None 0 0 0 0 0
E/K 22420 Fn3-50 67 rs530426755 0.3691 0.514 0.92 N 0.434 0.293 0.264081493735 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
E/K 22420 Fn3-50 67 rs530426755 0.3691 0.514 0.92 N 0.434 0.293 0.264081493735 gnomAD-4.0.0 6.57099E-06 None None None None N None 0 0 None 0 1.94553E-04 None 0 0 0 0 0
E/Q 23206 Fn3-56 68 rs1244129033 0.2429 0.27 0.997 N 0.726 0.342 0.367803931526 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
E/Q 23206 Fn3-56 68 rs1244129033 0.2429 0.27 0.997 N 0.726 0.342 0.367803931526 gnomAD-4.0.0 2.05282E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69867E-06 0 0
E/K 23501 Fn3-58 67 rs1709809170 0.4001 None 0.997 N 0.71 0.361 0.48087575253 gnomAD-4.0.0 4.77544E-06 None None None None N None 0 2.28655E-05 None 0 0 None 0 0 0 2.86615E-05 0
T/A 23793 Fn3-60 68 None 0.0795 None 0.349 N 0.401 0.131 0.151104730317 gnomAD-4.0.0 1.36947E-06 None None None None N None 0 0 None 0 0 None 0 0 8.9997E-07 0 1.65826E-05
T/S 23793 Fn3-60 68 rs1709465876 0.1349 None 0.722 N 0.403 0.151 0.195762928549 gnomAD-4.0.0 1.36947E-06 None None None None N None 5.97872E-05 0 None 0 0 None 0 0 0 0 0
D/E 23893 Fn3-61 68 rs777818650 0.2003 None 0.067 N 0.225 0.118 0.112648838833 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
D/E 23893 Fn3-61 68 rs777818650 0.2003 None 0.067 N 0.225 0.118 0.112648838833 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/E 23893 Fn3-61 68 rs777818650 0.2003 None 0.067 N 0.225 0.118 0.112648838833 gnomAD-4.0.0 1.05362E-05 None None None None N None 0 0 None 0 0 None 0 0 1.35632E-05 0 1.60123E-05
D/N 23893 Fn3-61 68 rs753690633 0.1515 -0.029 0.988 N 0.732 0.363 0.240491677333 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.56E-05 0
D/N 23893 Fn3-61 68 rs753690633 0.1515 -0.029 0.988 N 0.732 0.363 0.240491677333 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
D/N 23893 Fn3-61 68 rs753690633 0.1515 -0.029 0.988 N 0.732 0.363 0.240491677333 gnomAD-4.0.0 1.54942E-05 None None None None N None 0 0 None 0 0 None 0 0 2.11929E-05 0 0
D/V 23893 Fn3-61 68 rs1449843654 0.3607 0.092 0.994 N 0.686 0.507 0.544037764837 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
D/V 23893 Fn3-61 68 rs1449843654 0.3607 0.092 0.994 N 0.686 0.507 0.544037764837 gnomAD-4.0.0 8.21141E-06 None None None None N None 0 0 None 0 0 None 0 0 1.07948E-05 0 0
E/G 23991 Fn3-62 68 None 0.4366 None 1.0 N 0.646 0.602 0.516381326315 gnomAD-4.0.0 1.59171E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8591E-06 0 0
K/R 24189 Fn3-63 68 None 0.081 None 0.977 N 0.651 0.282 0.457922657367 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
E/D 24391 Fn3-65 69 None 0.2686 None 0.999 N 0.571 0.294 0.414798848334 gnomAD-4.0.0 6.84461E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99635E-07 0 0
E/G 24391 Fn3-65 69 None 0.2216 None 1.0 N 0.591 0.528 0.532503582573 gnomAD-4.0.0 1.36891E-06 None None None None N None 0 0 None 0 2.53126E-05 None 0 0 0 0 1.65766E-05
E/K 24391 Fn3-65 69 rs1479035090 0.1945 0.05 0.999 N 0.671 0.348 0.423836183345 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 4.65E-05 0 0
E/K 24391 Fn3-65 69 rs1479035090 0.1945 0.05 0.999 N 0.671 0.348 0.423836183345 gnomAD-4.0.0 6.84461E-07 None None None None N None 0 0 None 0 0 None 1.87364E-05 0 0 0 0
E/Q 24391 Fn3-65 69 None 0.1653 None 1.0 N 0.648 0.353 0.371903410333 gnomAD-4.0.0 2.05338E-06 None None None None N None 0 0 None 0 0 None 0 0 2.6989E-06 0 0
Q/R 24681 Fn3-67 66 rs537071956 0.1642 0.108 0.201 N 0.459 0.178 0.203808441222 gnomAD-2.1.1 4.08444E-04 None None None None N None 0 0 None 0 5.12529E-03 None 4.90838E-04 None 0 0 0
Q/R 24681 Fn3-67 66 rs537071956 0.1642 0.108 0.201 N 0.459 0.178 0.203808441222 gnomAD-3.1.2 1.77517E-04 None None None None N None 0 0 0 0 4.84496E-03 None 0 0 1.47E-05 2.06954E-04 0
Q/R 24681 Fn3-67 66 rs537071956 0.1642 0.108 0.201 N 0.459 0.178 0.203808441222 1000 genomes 9.98403E-04 None None None None N None 0 0 None None 4E-03 0 None None None 1E-03 None
Q/R 24681 Fn3-67 66 rs537071956 0.1642 0.108 0.201 N 0.459 0.178 0.203808441222 gnomAD-4.0.0 1.15295E-04 None None None None N None 0 0 None 0 3.15606E-03 None 0 0 1.69558E-06 3.40472E-04 1.92141E-04
T/A 24875 Fn3-68 68 rs770565202 0.132 -0.651 0.919 N 0.453 0.214 0.276898752692 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.68E-05 0
T/A 24875 Fn3-68 68 rs770565202 0.132 -0.651 0.919 N 0.453 0.214 0.276898752692 gnomAD-4.0.0 7.96194E-06 None None None None N None 0 0 None 0 0 None 0 0 1.42976E-05 0 0
T/S 24875 Fn3-68 68 rs536979672 0.2138 -0.574 0.958 N 0.485 0.223 0.305086939656 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 8.95E-06 0
T/S 24875 Fn3-68 68 rs536979672 0.2138 -0.574 0.958 N 0.485 0.223 0.305086939656 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/S 24875 Fn3-68 68 rs536979672 0.2138 -0.574 0.958 N 0.485 0.223 0.305086939656 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
T/S 24875 Fn3-68 68 rs536979672 0.2138 -0.574 0.958 N 0.485 0.223 0.305086939656 gnomAD-4.0.0 2.56352E-06 None None None None N None 1.68833E-05 0 None 0 0 None 0 0 0 1.34041E-05 0
E/G 24975 Fn3-69 68 rs548753396 0.3602 -0.95 1.0 N 0.596 0.426 0.586756053714 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06954E-04 0
E/G 24975 Fn3-69 68 rs548753396 0.3602 -0.95 1.0 N 0.596 0.426 0.586756053714 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
E/G 24975 Fn3-69 68 rs548753396 0.3602 -0.95 1.0 N 0.596 0.426 0.586756053714 gnomAD-4.0.0 6.57065E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07125E-04 0
E/G 25271 Fn3-71 68 rs1163400034 0.2438 -0.789 0.324 N 0.453 0.325 0.372087925617 gnomAD-2.1.1 7.17E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.57E-05 0
E/G 25271 Fn3-71 68 rs1163400034 0.2438 -0.789 0.324 N 0.453 0.325 0.372087925617 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/G 25271 Fn3-71 68 rs1163400034 0.2438 -0.789 0.324 N 0.453 0.325 0.372087925617 gnomAD-4.0.0 1.02553E-05 None None None None N None 0 0 None 0 0 None 0 0 1.91524E-05 0 0
E/A 25371 Fn3-72 68 None 0.2762 None 0.999 N 0.632 0.551 0.415820034956 gnomAD-4.0.0 6.84443E-07 None None None None N None 0 2.23724E-05 None 0 0 None 0 0 0 0 0
E/K 25371 Fn3-72 68 rs755460020 0.3241 -0.148 0.999 N 0.703 0.362 0.427368086475 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.6E-05 None 0 None 0 0 0
E/K 25371 Fn3-72 68 rs755460020 0.3241 -0.148 0.999 N 0.703 0.362 0.427368086475 gnomAD-4.0.0 3.18516E-06 None None None None N None 0 0 None 0 5.55895E-05 None 0 0 0 0 0
E/Q 25371 Fn3-72 68 None 0.2319 None 1.0 N 0.681 0.381 0.371344866733 gnomAD-4.0.0 1.59258E-06 None None None None N None 0 0 None 0 2.77948E-05 None 0 0 0 0 0
E/G 25473 Fn3-73 69 None 0.2264 None 0.988 N 0.68 0.482 0.458191732957 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
E/G 25667 Fn3-74 67 rs777038781 0.6353 -0.949 1.0 N 0.607 0.555 0.656895726345 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
E/G 25667 Fn3-74 67 rs777038781 0.6353 -0.949 1.0 N 0.607 0.555 0.656895726345 gnomAD-4.0.0 3.18409E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71994E-06 0 0
Q/K 25763 Fn3-75 66 None 0.114 None 0.09 N 0.112 0.132 0.158396225186 gnomAD-4.0.0 1.5929E-06 None None None None N None 0 0 None 0 0 None 1.89415E-05 0 0 0 0
Q/P 25763 Fn3-75 66 None 0.0928 None 0.997 N 0.418 0.424 0.230578612272 gnomAD-4.0.0 2.73845E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69941E-06 0 1.65733E-05
Q/R 25763 Fn3-75 66 None 0.1341 None 0.852 N 0.463 0.239 0.193865811164 gnomAD-4.0.0 6.84584E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99756E-07 0 0
T/I 25957 Fn3-76 68 rs372165943 0.2775 -0.149 0.97 N 0.463 0.409 None gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
T/I 25957 Fn3-76 68 rs372165943 0.2775 -0.149 0.97 N 0.463 0.409 None gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
T/I 25957 Fn3-76 68 rs372165943 0.2775 -0.149 0.97 N 0.463 0.409 None gnomAD-4.0.0 3.84461E-06 None None None None N None 5.07717E-05 0 None 0 0 None 0 0 0 0 0
E/K 26155 Fn3-78 68 rs778395291 0.4783 0.129 0.999 N 0.705 0.356 0.436993770938 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
E/K 26155 Fn3-78 68 rs778395291 0.4783 0.129 0.999 N 0.705 0.356 0.436993770938 gnomAD-4.0.0 1.59479E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43534E-05 0
E/D 26453 Fn3-80 68 rs1299909025 0.3389 -0.516 0.999 N 0.552 0.316 0.301455362545 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
E/D 26453 Fn3-80 68 rs1299909025 0.3389 -0.516 0.999 N 0.552 0.316 0.301455362545 gnomAD-4.0.0 1.59214E-06 None None None None N None 0 0 None 0 2.77608E-05 None 0 0 0 0 0
E/K 26453 Fn3-80 68 None 0.3112 None 0.999 N 0.666 0.385 0.483224754729 gnomAD-4.0.0 1.59227E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85889E-06 0 0
E/V 26453 Fn3-80 68 None 0.3992 None 1.0 N 0.669 0.513 0.652849316004 gnomAD-4.0.0 1.59213E-06 None None None None N None 5.65867E-05 0 None 0 0 None 0 0 0 0 0
E/K 26749 Fn3-82 67 None 0.4864 None 0.997 N 0.703 0.439 0.403469152278 gnomAD-4.0.0 1.36854E-06 None None None None N None 2.98864E-05 2.23634E-05 None 0 0 None 0 0 0 0 0
E/K 27139 Fn3-85 68 rs763198311 0.4693 -0.172 0.998 N 0.654 0.427 0.583897100485 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
E/K 27139 Fn3-85 68 rs763198311 0.4693 -0.172 0.998 N 0.654 0.427 0.583897100485 gnomAD-4.0.0 2.05336E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.31959E-05 1.65766E-05
P/S 27436 Fn3-87 68 None 0.1299 None 0.521 D 0.376 0.336 0.269558022972 gnomAD-4.0.0 3.18268E-06 None None None None N None 0 0 None 0 5.5497E-05 None 0 0 0 0 0
E/K 27536 Fn3-88 68 rs745974517 0.2295 0.062 0.989 N 0.58 0.339 0.383590876969 gnomAD-2.1.1 3.62E-05 None None None None N None 1.29182E-04 0 None 0 2.22941E-04 None 3.27E-05 None 4.64E-05 8.88E-06 0
E/K 27536 Fn3-88 68 rs745974517 0.2295 0.062 0.989 N 0.58 0.339 0.383590876969 gnomAD-4.0.0 1.09474E-05 None None None None N None 5.97693E-05 0 None 0 1.00806E-04 None 1.87259E-05 1.7343E-04 3.59789E-06 2.31868E-05 3.31345E-05
E/V 27832 Fn3-90 67 rs746250521 0.3749 -0.16 0.704 N 0.481 0.371 0.504418060211 gnomAD-2.1.1 4.21E-06 None None None None N None 0 0 None 0 5.76E-05 None 0 None 0 0 0
E/V 27832 Fn3-90 67 rs746250521 0.3749 -0.16 0.704 N 0.481 0.371 0.504418060211 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.9305E-04 None 0 0 0 0 0
E/V 27832 Fn3-90 67 rs746250521 0.3749 -0.16 0.704 N 0.481 0.371 0.504418060211 gnomAD-4.0.0 6.57203E-06 None None None None N None 0 0 None 0 1.9305E-04 None 0 0 0 0 0
A/S 27928 Fn3-91 66 rs1703988873 0.0838 None 0.042 N 0.395 0.101 0.12205267543 gnomAD-4.0.0 7.99859E-06 None None None None N None 0 0 None 0 1.38819E-04 None 0 0 0 0 0
A/V 27928 Fn3-91 66 None 0.0952 None None N 0.111 0.131 0.186928172975 gnomAD-4.0.0 2.74201E-06 None None None None N None 0 0 None 0 0 None 0 0 3.60112E-06 0 0
T/I 28121 Fn3-92 67 None 0.2342 None 0.939 N 0.431 0.3 0.32980341726 gnomAD-4.0.0 6.843E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99518E-07 0 0
T/K 28121 Fn3-92 67 rs397517726 0.1421 -0.3 0.521 N 0.338 0.229 0.269111216191 gnomAD-2.1.1 2.15E-05 None None None None N None 0 1.41611E-04 None 0 0 None 0 None 0 0 1.40845E-04
T/K 28121 Fn3-92 67 rs397517726 0.1421 -0.3 0.521 N 0.338 0.229 0.269111216191 gnomAD-3.1.2 4.6E-05 None None None None N None 2.41E-05 2.61986E-04 0 0 0 None 0 0 0 0 9.56938E-04
T/K 28121 Fn3-92 67 rs397517726 0.1421 -0.3 0.521 N 0.338 0.229 0.269111216191 gnomAD-4.0.0 1.05359E-05 None None None None N None 1.33483E-05 1.83394E-04 None 0 0 None 0 0 8.4764E-07 0 6.40451E-05
T/R 28121 Fn3-92 67 rs397517726 0.1201 0.045 0.684 N 0.433 0.291 0.33110744837 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
T/R 28121 Fn3-92 67 rs397517726 0.1201 0.045 0.684 N 0.433 0.291 0.33110744837 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/R 28121 Fn3-92 67 rs397517726 0.1201 0.045 0.684 N 0.433 0.291 0.33110744837 gnomAD-4.0.0 1.23942E-06 None None None None N None 2.66532E-05 0 None 0 0 None 0 0 0 0 0
E/G 28221 Fn3-93 68 None 0.4859 None 0.892 N 0.438 0.44 0.42886291518 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 28221 Fn3-93 68 rs1309034017 0.4088 0.146 0.805 N 0.521 0.308 0.346315397577 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
E/K 28221 Fn3-93 68 rs1309034017 0.4088 0.146 0.805 N 0.521 0.308 0.346315397577 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
E/K 28221 Fn3-93 68 rs1309034017 0.4088 0.146 0.805 N 0.521 0.308 0.346315397577 gnomAD-4.0.0 6.57099E-06 None None None None N None 2.41196E-05 0 None 0 0 None 0 0 0 0 0
E/A 28319 Fn3-94 68 rs903892310 0.3658 -0.684 0.958 N 0.645 0.507 0.393623145366 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
E/A 28319 Fn3-94 68 rs903892310 0.3658 -0.684 0.958 N 0.645 0.507 0.393623145366 gnomAD-4.0.0 6.36685E-06 None None None None N None 0 9.14746E-05 None 0 0 None 0 0 0 0 0
E/D 28319 Fn3-94 68 None 0.6527 None 0.067 N 0.199 0.166 0.191931220699 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 28319 Fn3-94 68 None 0.5085 None 0.958 N 0.635 0.401 0.384919354899 gnomAD-4.0.0 1.59175E-06 None None None None N None 0 0 None 0 0 None 1.88865E-05 0 0 0 0
T/A 28717 Fn3-97 67 rs757567360 0.0572 -0.506 None N 0.045 0.037 0.0762999501168 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 1.30745E-04 None 0 0 0
T/A 28717 Fn3-97 67 rs757567360 0.0572 -0.506 None N 0.045 0.037 0.0762999501168 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
T/A 28717 Fn3-97 67 rs757567360 0.0572 -0.506 None N 0.045 0.037 0.0762999501168 gnomAD-4.0.0 7.43644E-06 None None None None N None 0 0 None 0 0 None 0 0 8.47587E-07 9.88121E-05 3.20215E-05
E/A 28911 Fn3-98 67 rs370232500 0.2779 None 0.995 N 0.649 0.509 0.423480098753 gnomAD-4.0.0 1.59211E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02554E-05
E/G 28911 Fn3-98 67 None 0.4954 None 1.0 N 0.603 0.518 0.504541157375 gnomAD-4.0.0 1.59211E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86082E-06 0 0
E/K 28911 Fn3-98 67 None 0.5042 None 0.997 N 0.705 0.333 0.407082143382 gnomAD-4.0.0 2.40069E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62506E-06 0 0
T/A 29204 Fn3-100 68 None 0.0636 None 0.477 N 0.427 0.188 0.21737058555 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/I 29204 Fn3-100 68 rs72648228 0.147 -0.316 0.928 N 0.45 0.274 0.309530620856 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.56E-05 None 0 None 0 0 0
T/I 29204 Fn3-100 68 rs72648228 0.147 -0.316 0.928 N 0.45 0.274 0.309530620856 gnomAD-4.0.0 6.84163E-07 None None None None N None 0 0 None 0 2.51889E-05 None 0 0 0 0 0
T/K 29204 Fn3-100 68 None 0.1148 None 0.006 N 0.267 0.146 0.213573922156 gnomAD-4.0.0 6.84163E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99421E-07 0 0
T/P 29204 Fn3-100 68 rs765145227 0.0817 -0.444 0.928 N 0.449 0.298 0.20549828249 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
T/P 29204 Fn3-100 68 rs765145227 0.0817 -0.444 0.928 N 0.449 0.298 0.20549828249 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/P 29204 Fn3-100 68 rs765145227 0.0817 -0.444 0.928 N 0.449 0.298 0.20549828249 gnomAD-4.0.0 6.56883E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46981E-05 0 0
T/R 29204 Fn3-100 68 rs72648228 0.1052 -0.301 0.761 N 0.427 0.104 None gnomAD-2.1.1 1.96155E-04 None None None None N None 2.23141E-03 2.83E-05 None 0 0 None 0 None 0 0 0
T/R 29204 Fn3-100 68 rs72648228 0.1052 -0.301 0.761 N 0.427 0.104 None gnomAD-3.1.2 5.12517E-04 None None None None N None 1.7852E-03 1.96309E-04 0 0 0 None 0 0 0 0 4.78469E-04
T/R 29204 Fn3-100 68 rs72648228 0.1052 -0.301 0.761 N 0.427 0.104 None 1000 genomes 1.39776E-03 None None None None N None 5.3E-03 0 None None 0 0 None None None 0 None
T/R 29204 Fn3-100 68 rs72648228 0.1052 -0.301 0.761 N 0.427 0.104 None gnomAD-4.0.0 1.05951E-04 None None None None N None 2.0785E-03 9.99633E-05 None 0 0 None 0 0 0 0 1.44041E-04
A/P 29304 Fn3-101 68 rs571668367 0.1727 -0.297 0.999 N 0.709 0.243 0.191931220699 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/P 29304 Fn3-101 68 rs571668367 0.1727 -0.297 0.999 N 0.709 0.243 0.191931220699 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
A/P 29304 Fn3-101 68 rs571668367 0.1727 -0.297 0.999 N 0.709 0.243 0.191931220699 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
A/P 29304 Fn3-101 68 rs571668367 0.1727 -0.297 0.999 N 0.709 0.243 0.191931220699 gnomAD-4.0.0 1.23919E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.09789E-05 1.60036E-05
A/T 29304 Fn3-101 68 rs571668367 0.1699 -0.712 0.992 N 0.655 0.287 0.264547087235 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
A/T 29304 Fn3-101 68 rs571668367 0.1699 -0.712 0.992 N 0.655 0.287 0.264547087235 gnomAD-4.0.0 2.05247E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69825E-06 0 0
A/V 29304 Fn3-101 68 None 0.3085 None 0.998 N 0.676 0.391 0.461408135625 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
Q/E 29402 Fn3-102 68 None 0.0851 None 0.953 N 0.463 0.219 0.185906805712 gnomAD-4.0.0 1.5913E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
K/I 29600 Fn3-103 68 rs548209283 0.5651 0.527 0.999 N 0.653 0.368 0.561867705733 gnomAD-2.1.1 2.41E-05 None None None None N None 0 0 None 0 0 None 1.96066E-04 None 0 0 0
K/I 29600 Fn3-103 68 rs548209283 0.5651 0.527 0.999 N 0.653 0.368 0.561867705733 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 0 4.1425E-04 0
K/I 29600 Fn3-103 68 rs548209283 0.5651 0.527 0.999 N 0.653 0.368 0.561867705733 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
K/I 29600 Fn3-103 68 rs548209283 0.5651 0.527 0.999 N 0.653 0.368 0.561867705733 gnomAD-4.0.0 1.15267E-05 None None None None N None 0 0 None 0 0 None 0 2.25225E-04 0 1.0721E-04 0
E/K 29700 Fn3-104 68 rs1301227457 0.3148 0.21 0.999 N 0.691 0.365 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
E/K 29700 Fn3-104 68 rs1301227457 0.3148 0.21 0.999 N 0.691 0.365 None gnomAD-4.0.0 1.59198E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02407E-05
E/V 29700 Fn3-104 68 rs763490789 0.4111 -0.096 1.0 N 0.643 0.588 0.690242091961 gnomAD-4.0.0 2.053E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.47802E-05 0
P/H 29802 Fn3-105 69 rs769366983 0.3104 -0.597 0.071 N 0.315 0.365 0.435262743402 gnomAD-2.1.1 1.61E-05 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 1.78E-05 0
P/H 29802 Fn3-105 69 rs769366983 0.3104 -0.597 0.071 N 0.315 0.365 0.435262743402 gnomAD-4.0.0 7.52613E-06 None None None None N None 0 4.47227E-05 None 0 0 None 0 0 5.39675E-06 0 4.96952E-05
P/L 29802 Fn3-105 69 rs769366983 0.1777 None 0.89 N 0.543 0.431 0.627983267216 gnomAD-4.0.0 6.84194E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99459E-07 0 0
P/R 29802 Fn3-105 69 None 0.3341 None 0.942 N 0.551 0.459 0.511390160789 gnomAD-4.0.0 6.84194E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15939E-05 0
P/S 29802 Fn3-105 69 rs1301048848 0.1684 -0.789 0.698 N 0.437 0.323 0.299427821978 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
P/S 29802 Fn3-105 69 rs1301048848 0.1684 -0.789 0.698 N 0.437 0.323 0.299427821978 gnomAD-4.0.0 2.05256E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69835E-06 0 0
P/T 29802 Fn3-105 69 None 0.1049 None 0.058 N 0.249 0.281 0.409800938858 gnomAD-4.0.0 6.84187E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9945E-07 0 0
E/V 29999 Fn3-106 67 rs1249458719 0.3949 None 0.961 N 0.411 0.295 0.592282861509 gnomAD-4.0.0 1.5913E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85802E-06 0 0
E/G 30095 Fn3-107 66 rs766497887 0.3584 -1.194 1.0 N 0.589 0.545 0.587690973971 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
E/G 30095 Fn3-107 66 rs766497887 0.3584 -1.194 1.0 N 0.589 0.545 0.587690973971 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
E/G 30095 Fn3-107 66 rs766497887 0.3584 -1.194 1.0 N 0.589 0.545 0.587690973971 gnomAD-4.0.0 5.12357E-06 None None None None N None 0 3.38949E-05 None 0 0 None 0 0 4.78535E-06 0 0
K/R 30291 Fn3-108 68 rs1575514675 0.1003 None 0.999 N 0.687 0.347 0.292787519742 gnomAD-4.0.0 1.59207E-06 None None None None N None 0 0 None 4.77236E-05 0 None 0 0 0 0 0
E/D 30391 Fn3-109 68 rs199505541 0.5187 -0.454 0.999 N 0.583 0.37 0.396494342077 gnomAD-2.1.1 3.4656E-04 None None None None N None 4.13E-05 8.49E-05 None 7.64615E-03 0 None 0 None 0 9.39E-05 2.81373E-04
E/D 30391 Fn3-109 68 rs199505541 0.5187 -0.454 0.999 N 0.583 0.37 0.396494342077 gnomAD-3.1.2 2.29933E-04 None None None None N None 2.41E-05 0 0 8.07848E-03 0 None 0 0 5.88E-05 0 9.5511E-04
E/D 30391 Fn3-109 68 rs199505541 0.5187 -0.454 0.999 N 0.583 0.37 0.396494342077 gnomAD-4.0.0 2.13793E-04 None None None None N None 2.66966E-05 5.00017E-05 None 8.51581E-03 0 None 0 0 4.32283E-05 0 5.92417E-04
E/Q 30391 Fn3-109 68 rs758395481 0.4724 -0.043 1.0 N 0.682 0.33 0.42989457901 gnomAD-2.1.1 8.05E-06 None None None None N None 6.46E-05 2.9E-05 None 0 0 None 0 None 0 0 0
E/Q 30391 Fn3-109 68 rs758395481 0.4724 -0.043 1.0 N 0.682 0.33 0.42989457901 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
E/Q 30391 Fn3-109 68 rs758395481 0.4724 -0.043 1.0 N 0.682 0.33 0.42989457901 gnomAD-4.0.0 1.85907E-06 None None None None N None 1.33451E-05 1.66678E-05 None 0 0 None 0 0 8.47617E-07 0 0
P/L 30488 Fn3-110 67 rs868503876 0.1433 None 0.896 N 0.56 0.539 0.664074601257 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
N/I 30686 Fn3-111 68 None 0.1283 None 0.029 N 0.481 0.069 0.211220785272 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/E 30888 Fn3-113 68 None 0.1893 None 0.004 N 0.239 0.301 0.184867976434 gnomAD-4.0.0 6.8418E-07 None None None None N None 2.98793E-05 0 None 0 0 None 0 0 0 0 0
A/V 30888 Fn3-113 68 rs1393497190 0.107 -0.438 0.549 N 0.401 0.272 0.258779203287 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
A/V 30888 Fn3-113 68 rs1393497190 0.107 -0.438 0.549 N 0.401 0.272 0.258779203287 gnomAD-4.0.0 2.05254E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99441E-07 0 3.31301E-05
E/D 31082 Fn3-114 67 None 0.3069 None 0.959 N 0.447 0.329 0.500488203797 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
E/K 31082 Fn3-114 67 rs199663613 0.2913 0.405 0.992 N 0.448 0.344 None gnomAD-2.1.1 6.44E-05 None None None None N None 5.78991E-04 2.83E-05 None 0 0 None 3.27E-05 None 0 1.57E-05 0
E/K 31082 Fn3-114 67 rs199663613 0.2913 0.405 0.992 N 0.448 0.344 None gnomAD-3.1.2 1.64296E-04 None None None None N None 5.78983E-04 6.55E-05 0 0 0 None 0 0 0 0 0
E/K 31082 Fn3-114 67 rs199663613 0.2913 0.405 0.992 N 0.448 0.344 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
E/K 31082 Fn3-114 67 rs199663613 0.2913 0.405 0.992 N 0.448 0.344 None gnomAD-4.0.0 4.21347E-05 None None None None N None 6.6624E-04 1.66633E-05 None 0 0 None 0 0 8.47585E-06 3.29388E-05 6.40143E-05
K/N 31375 Fn3-116 68 None 0.7849 None 1.0 N 0.659 0.293 0.235664433957 gnomAD-4.0.0 3.18424E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86689E-05 0
E/Q 31475 Fn3-117 68 rs1171182062 0.5326 0.206 1.0 N 0.661 0.381 0.294918367191 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
E/Q 31475 Fn3-117 68 rs1171182062 0.5326 0.206 1.0 N 0.661 0.381 0.294918367191 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/Q 31475 Fn3-117 68 rs1171182062 0.5326 0.206 1.0 N 0.661 0.381 0.294918367191 gnomAD-4.0.0 6.57177E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46972E-05 0 0
E/D 31576 Fn3-118 71 rs1363584144 0.4541 -0.391 0.999 N 0.603 0.308 0.280181792013 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
E/D 31576 Fn3-118 71 rs1363584144 0.4541 -0.391 0.999 N 0.603 0.308 0.280181792013 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
E/D 31576 Fn3-118 71 rs1363584144 0.4541 -0.391 0.999 N 0.603 0.308 0.280181792013 gnomAD-4.0.0 1.31425E-05 None None None None N None 0 0 None 0 0 None 0 0 2.94014E-05 0 0
K/E 31774 Fn3-119 67 rs762265902 0.1923 0.029 0.999 N 0.675 0.402 None gnomAD-2.1.1 5.36E-05 None None None None N None 4.13E-05 0 None 0 0 None 0 None 0 1.09443E-04 0
K/E 31774 Fn3-119 67 rs762265902 0.1923 0.029 0.999 N 0.675 0.402 None gnomAD-3.1.2 7.23E-05 None None None None N None 2.41E-05 0 0 0 1.9253E-04 None 0 0 1.32295E-04 0 0
K/E 31774 Fn3-119 67 rs762265902 0.1923 0.029 0.999 N 0.675 0.402 None gnomAD-4.0.0 1.07814E-04 None None None None N None 3.99765E-05 0 None 3.37838E-05 2.22846E-05 None 0 0 1.40703E-04 0 4.80169E-05
E/K 31875 Fn3-120 69 rs371534086 0.4155 None 0.999 N 0.695 0.433 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
E/K 31875 Fn3-120 69 rs371534086 0.4155 None 0.999 N 0.695 0.433 None gnomAD-4.0.0 1.85935E-06 None None None None N None 2.67008E-05 0 None 0 0 None 0 0 0 0 1.60128E-05
M/I 31977 Fn3-121 69 rs1575423808 0.1247 None None N 0.049 0.103 0.158396225186 gnomAD-4.0.0 1.59137E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02425E-05
M/T 31977 Fn3-121 69 rs1481950216 0.0793 -1.091 None N 0.082 0.071 0.403752378121 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 9.96E-05 5.58E-05 None 0 None 0 0 0
M/T 31977 Fn3-121 69 rs1481950216 0.0793 -1.091 None N 0.082 0.071 0.403752378121 gnomAD-4.0.0 4.78959E-06 None None None None N None 0 0 None 3.82673E-05 2.51991E-05 None 0 0 4.49751E-06 0 0
E/K 32171 Fn3-122 67 rs778618339 0.5276 0.048 0.984 N 0.607 0.326 0.345175991111 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
E/K 32171 Fn3-122 67 rs778618339 0.5276 0.048 0.984 N 0.607 0.326 0.345175991111 gnomAD-4.0.0 1.59141E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85829E-06 0 0
E/D 32269 Fn3-123 68 rs876658095 0.3571 None 0.999 N 0.591 0.373 0.312608672186 gnomAD-4.0.0 6.36663E-06 None None None None N None 0 0 None 0 0 None 0 0 8.57814E-06 0 3.02499E-05
E/G 32269 Fn3-123 68 None 0.3247 None 1.0 N 0.601 0.548 0.630756395648 gnomAD-4.0.0 1.59167E-06 None None None None N None 0 0 None 0 2.77393E-05 None 0 0 0 0 0
E/K 32466 Fn3-124 68 rs55915651 0.471 0.783 1.0 N 0.678 0.434 0.483224754729 gnomAD-2.1.1 8.23E-05 None None None None N None 0 8.5E-05 None 0 6.18365E-04 None 3.27E-05 None 0 4.7E-05 1.40647E-04
E/K 32466 Fn3-124 68 rs55915651 0.471 0.783 1.0 N 0.678 0.434 0.483224754729 gnomAD-3.1.2 3.95E-05 None None None None N None 0 0 0 0 5.8117E-04 None 9.43E-05 0 2.94E-05 0 0
E/K 32466 Fn3-124 68 rs55915651 0.471 0.783 1.0 N 0.678 0.434 0.483224754729 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
E/K 32466 Fn3-124 68 rs55915651 0.471 0.783 1.0 N 0.678 0.434 0.483224754729 gnomAD-4.0.0 4.02855E-05 None None None None N None 0 5.00117E-05 None 0 4.2441E-04 None 6.25117E-05 0 3.22123E-05 1.09825E-05 0
E/Q 32466 Fn3-124 68 None 0.3645 None 1.0 N 0.661 0.385 0.356072328145 gnomAD-4.0.0 6.84307E-07 None None None None N None 2.98864E-05 0 None 0 0 None 0 0 0 0 0
E/D 32566 Fn3-125 68 None 0.4509 None 0.999 N 0.573 0.304 0.452072420954 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 32566 Fn3-125 68 rs1258453837 0.3824 0.196 0.999 N 0.681 0.395 0.426436156839 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 0 9.19118E-04
E/K 32566 Fn3-125 68 rs1258453837 0.3824 0.196 0.999 N 0.681 0.395 0.426436156839 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/K 32566 Fn3-125 68 rs1258453837 0.3824 0.196 0.999 N 0.681 0.395 0.426436156839 gnomAD-4.0.0 3.86381E-06 None None None None N None 0 0 None 0 0 None 1.57545E-05 0 4.8091E-06 0 0
E/G 32862 Fn3-127 68 rs754522958 0.4476 -1.271 1.0 N 0.669 0.551 0.683498201844 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
E/G 32862 Fn3-127 68 rs754522958 0.4476 -1.271 1.0 N 0.669 0.551 0.683498201844 gnomAD-4.0.0 1.59116E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
E/K 32862 Fn3-127 68 rs1693326100 0.583 None 0.999 N 0.677 0.383 0.486135451721 gnomAD-4.0.0 3.42093E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49728E-06 0 0
E/V 32862 Fn3-127 68 rs754522958 0.6913 -0.115 1.0 N 0.679 0.554 0.711382389189 gnomAD-2.1.1 1.2E-05 None None None None N None 0 8.69E-05 None 0 0 None 0 None 0 0 0
E/V 32862 Fn3-127 68 rs754522958 0.6913 -0.115 1.0 N 0.679 0.554 0.711382389189 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.54E-05 0 0 0 None 0 0 0 0 0
E/V 32862 Fn3-127 68 rs754522958 0.6913 -0.115 1.0 N 0.679 0.554 0.711382389189 gnomAD-4.0.0 5.12399E-06 None None None None N None 0 6.77782E-05 None 0 0 None 0 0 0 0 0
P/A 32964 Fn3-128 69 rs750948702 0.1021 None 0.996 D 0.591 0.482 0.415820034956 gnomAD-4.0.0 1.16318E-05 None None None None N None 0 0 None 0 0 None 0 0 1.52916E-05 0 0
P/S 32964 Fn3-128 69 rs750948702 0.2021 -1.161 0.998 D 0.676 0.521 0.445614145163 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
P/S 32964 Fn3-128 69 rs750948702 0.2021 -1.161 0.998 D 0.676 0.521 0.445614145163 gnomAD-4.0.0 2.7369E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59802E-06 0 0
E/A 33358 Fn3-130 69 None 0.3618 None 0.999 N 0.66 0.517 0.368743488249 gnomAD-4.0.0 1.36894E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79929E-06 0 0
G/E 33754 Fn3-132 66 rs760939553 0.9757 -1.235 1.0 N 0.825 0.523 0.293147016451 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 1.11297E-04 None 0 None 0 0 0
G/E 33754 Fn3-132 66 rs760939553 0.9757 -1.235 1.0 N 0.825 0.523 0.293147016451 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92456E-04 None 0 0 0 0 0
G/E 33754 Fn3-132 66 rs760939553 0.9757 -1.235 1.0 N 0.825 0.523 0.293147016451 gnomAD-4.0.0 1.859E-06 None None None None N None 0 0 None 0 6.68241E-05 None 0 0 0 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.