Structural position:

  • Domain Type: Ig
  • Aligned Position: 1
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
P/L 6 Ig-1 1 rs201490999 0.942 -0.477 1.0 D 0.885 0.556 0.94644319945 gnomAD-2.1.1 1.2E-05 None None None -1.449(TCAP) N None 6.16E-05 0 None 0 0 None 0 None 0 1.76E-05 0
P/L 6 Ig-1 1 rs201490999 0.942 -0.477 1.0 D 0.885 0.556 0.94644319945 gnomAD-3.1.2 1.31E-05 None None None -1.449(TCAP) N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 6 Ig-1 1 rs201490999 0.942 -0.477 1.0 D 0.885 0.556 0.94644319945 gnomAD-4.0.0 3.53224E-05 None None None -1.449(TCAP) N None 4.00598E-05 1.66728E-05 None 0 0 None 0 0 4.40718E-05 0 1.60092E-05
P/S 104 Ig-2 1 rs752692701 0.8423 -2.306 1.0 D 0.909 0.762 0.763886952847 gnomAD-2.1.1 8.09E-06 None None None -0.724(TCAP) N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
P/S 104 Ig-2 1 rs752692701 0.8423 -2.306 1.0 D 0.909 0.762 0.763886952847 gnomAD-4.0.0 8.013E-06 None None None -0.724(TCAP) N None 0 0 None 0 0 None 0 0 1.43814E-05 0 0
P/L 943 Ig-3 1 rs577379388 0.9454 -0.732 1.0 D 0.79 0.865 0.871095129822 gnomAD-2.1.1 3.98E-06 None None None None N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
P/L 943 Ig-3 1 rs577379388 0.9454 -0.732 1.0 D 0.79 0.865 0.871095129822 gnomAD-3.1.2 6.59E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/L 943 Ig-3 1 rs577379388 0.9454 -0.732 1.0 D 0.79 0.865 0.871095129822 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
P/L 943 Ig-3 1 rs577379388 0.9454 -0.732 1.0 D 0.79 0.865 0.871095129822 gnomAD-4.0.0 2.03049E-06 None None None None N None 3.49626E-05 0 None 0 0 None 0 0 0 0 0
S/L 1291 Ig-5 1 rs192742099 0.2587 -0.438 0.012 N 0.357 0.278 None gnomAD-2.1.1 4E-06 None None None None N None 0 0 None 0 5.46E-05 None 0 None 0 0 0
S/L 1291 Ig-5 1 rs192742099 0.2587 -0.438 0.012 N 0.357 0.278 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92308E-04 None 0 0 0 0 0
S/L 1291 Ig-5 1 rs192742099 0.2587 -0.438 0.012 N 0.357 0.278 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
S/L 1291 Ig-5 1 rs192742099 0.2587 -0.438 0.012 N 0.357 0.278 None gnomAD-4.0.0 6.56927E-06 None None None None N None 0 0 None 0 1.92753E-04 None 0 0 0 0 0
P/A 1457 Ig-6 1 None 0.9002 None 1.0 D 0.827 0.709 0.816975189348 gnomAD-4.0.0 1.59072E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/L 1556 Ig-7 1 rs569025335 0.9856 -0.654 1.0 D 0.89 0.744 None gnomAD-2.1.1 7.1E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.56E-05 0
P/L 1556 Ig-7 1 rs569025335 0.9856 -0.654 1.0 D 0.89 0.744 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07727E-04 0
P/L 1556 Ig-7 1 rs569025335 0.9856 -0.654 1.0 D 0.89 0.744 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
P/L 1556 Ig-7 1 rs569025335 0.9856 -0.654 1.0 D 0.89 0.744 None gnomAD-4.0.0 9.91446E-06 None None None None N None 0 3.33433E-05 None 0 0 None 0 0 1.10175E-05 1.0981E-05 0
P/Q 1556 Ig-7 1 None 0.9987 -1.363 1.0 D 0.9 0.777 0.717363470281 gnomAD-2.1.1 7.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 1.64258E-04
P/Q 1556 Ig-7 1 None 0.9987 -1.363 1.0 D 0.9 0.777 0.717363470281 gnomAD-4.0.0 2.73681E-06 None None None None N None 0 0 None 0 0 None 1.87596E-05 0 2.69804E-06 0 0
P/R 1556 Ig-7 1 rs569025335 0.998 None 1.0 D 0.898 0.886 0.782170906113 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
P/R 1556 Ig-7 1 rs569025335 0.998 None 1.0 D 0.898 0.886 0.782170906113 gnomAD-4.0.0 1.2394E-06 None None None None N None 0 3.33545E-05 None 0 0 None 0 0 0 0 0
P/L 1703 Ig-8 1 None 0.9858 None 1.0 D 0.841 0.792 0.926848611622 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/T 1703 Ig-8 1 rs898070344 0.9891 None 1.0 D 0.828 0.817 0.862666556756 gnomAD-4.0.0 3.18127E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71295E-06 0 0
P/A 1841 Ig-9 1 rs2092223128 0.661 None 1.0 D 0.82 0.754 0.53832913131 gnomAD-4.0.0 1.59142E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/S 1841 Ig-9 1 None 0.9741 None 1.0 D 0.882 0.758 0.571137827458 gnomAD-4.0.0 1.59142E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85662E-06 0 0
P/T 1841 Ig-9 1 None 0.9489 None 1.0 D 0.878 0.793 0.614346839077 gnomAD-4.0.0 1.59142E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85662E-06 0 0
P/S 2078 Ig-10 1 rs777863327 0.9975 -2.02 1.0 D 0.882 0.779 0.796722845579 gnomAD-2.1.1 7.99E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 8.88E-06 0
P/S 2078 Ig-10 1 rs777863327 0.9975 -2.02 1.0 D 0.882 0.779 0.796722845579 gnomAD-4.0.0 1.27247E-05 None None None None N None 0 0 None 0 0 None 0 0 1.99958E-05 1.43271E-05 0
I/M 2174 Ig-11 1 rs1414401674 0.1268 -1.184 0.713 N 0.525 0.13 0.304108284078 gnomAD-2.1.1 7.98E-06 None None None None N None 0 2.89E-05 None 0 0 None 3.27E-05 None 0 0 0
I/M 2174 Ig-11 1 rs1414401674 0.1268 -1.184 0.713 N 0.525 0.13 0.304108284078 gnomAD-4.0.0 1.36834E-06 None None None None N None 0 2.23614E-05 None 0 0 None 0 0 0 1.15969E-05 0
I/V 2174 Ig-11 1 rs1171508892 0.0861 -1.425 0.001 N 0.309 0.089 0.245660935333 gnomAD-2.1.1 3.99E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
I/V 2174 Ig-11 1 rs1171508892 0.0861 -1.425 0.001 N 0.309 0.089 0.245660935333 gnomAD-4.0.0 3.18193E-06 None None None None N None 0 2.28645E-05 None 0 0 None 0 0 0 1.43279E-05 0
V/A 2267 Ig-12 1 None 0.1284 None 0.165 N 0.371 0.271 0.519514513453 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/F 2356 Ig-13 1 None 0.2527 None 0.549 D 0.267 0.51 0.659558603232 gnomAD-4.0.0 1.59064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85665E-06 0 0
I/L 2356 Ig-13 1 rs1561261813 0.127 -0.252 0.016 N 0.192 0.343 0.5073929853 gnomAD-2.1.1 4E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
I/M 2356 Ig-13 1 None 0.1025 None 0.045 D 0.169 0.243 0.52127940124 gnomAD-4.0.0 6.84097E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15934E-05 0
I/S 2356 Ig-13 1 rs2091912353 0.3794 None 0.549 D 0.313 0.617 0.821640738486 gnomAD-4.0.0 4.77204E-06 None None None None N None 0 0 None 0 0 None 0 4.82625E-04 0 0 3.02133E-05
I/T 2356 Ig-13 1 None 0.1603 None 0.549 D 0.291 0.509 0.755904203069 gnomAD-4.0.0 1.59068E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85669E-06 0 0
V/G 2445 Ig-14 1 None 0.6079 None 0.999 D 0.585 0.658 0.838309375149 gnomAD-4.0.0 3.60349E-06 None None None None I None 0 0 None 0 0 None 0 0 3.94021E-06 0 0
I/M 2533 Ig-15 1 None 0.2376 None 0.994 D 0.377 0.351 0.696815536761 gnomAD-4.0.0 1.59087E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43287E-05 0
I/N 2533 Ig-15 1 rs1247030843 0.7553 -0.292 0.998 D 0.511 0.593 0.890540186608 gnomAD-2.1.1 4.01E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
I/N 2533 Ig-15 1 rs1247030843 0.7553 -0.292 0.998 D 0.511 0.593 0.890540186608 gnomAD-4.0.0 1.59088E-06 None None None None N None 0 2.28728E-05 None 0 0 None 0 0 0 0 0
I/V 2533 Ig-15 1 rs372407708 0.137 -0.368 0.044 N 0.159 0.084 None gnomAD-2.1.1 2.14E-05 None None None None N None 2.47975E-04 0 None 0 0 None 0 None 0 0 0
I/V 2533 Ig-15 1 rs372407708 0.137 -0.368 0.044 N 0.159 0.084 None gnomAD-3.1.2 6.57E-05 None None None None N None 2.41289E-04 0 0 0 0 None 0 0 0 0 0
I/V 2533 Ig-15 1 rs372407708 0.137 -0.368 0.044 N 0.159 0.084 None gnomAD-4.0.0 1.11524E-05 None None None None N None 2.39866E-04 0 None 0 0 None 0 0 0 0 0
A/D 2621 Ig-16 1 rs753441258 0.7329 0.255 1.0 N 0.757 0.472 0.762034995844 gnomAD-2.1.1 6.37E-05 None None None None N None 0 4.04952E-04 None 0 0 None 0 None 0 0 3.26477E-04
A/D 2621 Ig-16 1 rs753441258 0.7329 0.255 1.0 N 0.757 0.472 0.762034995844 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
A/D 2621 Ig-16 1 rs753441258 0.7329 0.255 1.0 N 0.757 0.472 0.762034995844 gnomAD-4.0.0 9.91497E-06 None None None None N None 0 2.50083E-04 None 0 0 None 0 0 0 0 1.60077E-05
A/V 2621 Ig-16 1 rs753441258 0.4067 -0.105 1.0 D 0.666 0.361 0.640935244609 gnomAD-2.1.1 1.59E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.53E-05 0
A/V 2621 Ig-16 1 rs753441258 0.4067 -0.105 1.0 D 0.666 0.361 0.640935244609 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/V 2621 Ig-16 1 rs753441258 0.4067 -0.105 1.0 D 0.666 0.361 0.640935244609 gnomAD-4.0.0 8.6756E-06 None None None None N None 0 1.66722E-05 None 0 0 None 0 0 1.10188E-05 0 0
V/I 2707 Ig-17 1 rs376758159 0.1104 -0.008 0.997 D 0.501 0.448 None gnomAD-2.1.1 1.79E-05 None None None None N None 4.01E-05 0 None 0 0 None 0 None 1.32252E-04 7.77E-06 0
V/I 2707 Ig-17 1 rs376758159 0.1104 -0.008 0.997 D 0.501 0.448 None gnomAD-3.1.2 1.97E-05 None None None None N None 2.41E-05 0 0 0 0 None 9.42E-05 0 1.47E-05 0 0
V/I 2707 Ig-17 1 rs376758159 0.1104 -0.008 0.997 D 0.501 0.448 None gnomAD-4.0.0 9.00518E-06 None None None None N None 1.69233E-05 0 None 0 0 None 6.62208E-05 0 2.39202E-06 0 2.8456E-05
L/V 2882 Ig-19 1 None 0.1034 None 0.046 N 0.28 0.071 0.482500522706 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
I/V 2969 Ig-20 1 rs764394936 0.0814 -1.665 0.02 N 0.232 0.167 0.560529172091 gnomAD-2.1.1 9.97E-05 None None None None N None 0 6.94806E-04 None 0 0 None 0 None 0 8.83E-06 0
I/V 2969 Ig-20 1 rs764394936 0.0814 -1.665 0.02 N 0.232 0.167 0.560529172091 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.96412E-04 0 0 0 None 0 0 0 0 0
I/V 2969 Ig-20 1 rs764394936 0.0814 -1.665 0.02 N 0.232 0.167 0.560529172091 gnomAD-4.0.0 4.35647E-05 None None None None N None 0 5.25424E-04 None 0 0 None 0 0 7.17563E-06 0 0
I/L 3058 Ig-21 1 None 0.4437 None 0.993 N 0.385 0.243 0.28722502521 gnomAD-4.0.0 1.36822E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79861E-06 0 0
I/M 3058 Ig-21 1 rs1442547576 0.4594 -0.364 1.0 N 0.595 0.235 0.267755039894 gnomAD-2.1.1 3.99E-06 None None None None N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
I/M 3058 Ig-21 1 rs1442547576 0.4594 -0.364 1.0 N 0.595 0.235 0.267755039894 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/M 3058 Ig-21 1 rs1442547576 0.4594 -0.364 1.0 N 0.595 0.235 0.267755039894 gnomAD-4.0.0 6.56953E-06 None None None None N None 2.41231E-05 0 None 0 0 None 0 0 0 0 0
I/R 3058 Ig-21 1 None 0.9582 None 1.0 N 0.678 0.505 0.630135089153 gnomAD-4.0.0 1.59075E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
I/T 3058 Ig-21 1 rs373657576 0.7252 -0.524 1.0 N 0.546 0.476 0.473853734676 gnomAD-2.1.1 1.2E-05 None None None None N None 0 2.9E-05 None 0 1.09302E-04 None 0 None 0 0 0
I/T 3058 Ig-21 1 rs373657576 0.7252 -0.524 1.0 N 0.546 0.476 0.473853734676 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.9216E-04 None 0 0 0 0 0
I/T 3058 Ig-21 1 rs373657576 0.7252 -0.524 1.0 N 0.546 0.476 0.473853734676 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
I/T 3058 Ig-21 1 rs373657576 0.7252 -0.524 1.0 N 0.546 0.476 0.473853734676 gnomAD-4.0.0 2.561E-06 None None None None N None 0 1.69417E-05 None 0 2.42777E-05 None 0 0 0 0 0
I/V 3058 Ig-21 1 rs759240786 0.1585 -0.366 0.993 N 0.373 0.261 0.335910606209 gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 0 None 9.24E-05 8.84E-06 0
I/V 3058 Ig-21 1 rs759240786 0.1585 -0.366 0.993 N 0.373 0.261 0.335910606209 gnomAD-4.0.0 3.42056E-06 None None None None N None 0 0 None 0 0 None 5.61714E-05 0 8.99306E-07 0 1.65585E-05
V/I 3147 Ig-22 1 rs150283731 0.1016 -0.099 0.02 N 0.213 0.073 None gnomAD-2.1.1 3.98E-06 None None None None N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
P/L 3239 Ig-23 1 None 0.8789 None 1.0 D 0.887 0.796 0.877189934791 gnomAD-4.0.0 1.59277E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85771E-06 0 0
P/S 3239 Ig-23 1 rs1394280644 0.9395 -1.898 1.0 D 0.885 0.825 0.726327625402 gnomAD-2.1.1 4E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
P/S 3239 Ig-23 1 rs1394280644 0.9395 -1.898 1.0 D 0.885 0.825 0.726327625402 gnomAD-4.0.0 1.59279E-06 None None None None N None 0 2.28697E-05 None 0 0 None 0 0 0 0 0
P/L 3345 Ig-24 1 None 0.7644 None 1.0 D 0.905 0.83 0.913529028722 gnomAD-4.0.0 6.84103E-07 None None None None N None 0 0 None 0 2.52207E-05 None 0 0 0 0 0
P/R 3345 Ig-24 1 None 0.9806 None 1.0 D 0.91 0.854 0.853786399945 gnomAD-4.0.0 6.84103E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99319E-07 0 0
P/A 3660 Ig-26 1 None 0.2777 None None None None 0.226 None gnomAD-4.0.0 6.84229E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99457E-07 0 0
P/S 3660 Ig-26 1 rs375986676 0.545 -2.34 None None None 0.227 None gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
P/S 3660 Ig-26 1 rs375986676 0.545 -2.34 None None None 0.227 None gnomAD-4.0.0 3.42115E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49728E-06 0 0
P/S 3820 Ig-27 1 None 0.6741 None 1.0 D 0.802 0.586 None gnomAD-4.0.0 1.59188E-06 None None None None N None 0 2.28791E-05 None 0 0 None 0 0 0 0 0
P/S 3938 Ig-28 1 rs866702787 0.8685 None 1.0 D 0.921 0.646 None gnomAD-4.0.0 9.60257E-06 None None None None N None 0 0 None 0 0 None 0 0 9.18751E-06 6.07533E-05 0
P/L 4606 Ig-29 1 None 0.3665 None 1.0 D 0.911 0.624 None gnomAD-4.0.0 6.84201E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15934E-05 0
P/R 4606 Ig-29 1 rs762079270 0.7168 0.336 1.0 D 0.913 0.596 None gnomAD-2.1.1 1.21E-05 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 1.78E-05 0
P/R 4606 Ig-29 1 rs762079270 0.7168 0.336 1.0 D 0.913 0.596 None gnomAD-3.1.2 1.32E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 1.47E-05 0 0
P/R 4606 Ig-29 1 rs762079270 0.7168 0.336 1.0 D 0.913 0.596 None gnomAD-4.0.0 1.98317E-05 None None None None N None 2.67173E-05 0 None 0 0 None 0 0 2.45802E-05 0 1.60108E-05
P/A 4795 Ig-31 1 rs2081388960 0.6614 None 0.992 D 0.819 0.704 0.695824657773 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/A 4795 Ig-31 1 rs2081388960 0.6614 None 0.992 D 0.819 0.704 0.695824657773 gnomAD-4.0.0 6.57246E-06 None None None None N None 2.41301E-05 0 None 0 0 None 0 0 0 0 0
P/T 4795 Ig-31 1 None 0.9375 None 0.998 D 0.879 0.696 0.839827065042 gnomAD-4.0.0 7.00594E-07 None None None None N None 0 0 None 0 0 None 0 0 9.12825E-07 0 0
P/A 4888 Ig-32 1 rs376799249 0.6676 -1.59 1.0 D 0.838 0.685 0.112648838833 gnomAD-2.1.1 5.72E-05 None None None None N None 0 0 None 0 0 None 0 None 4E-05 1.09524E-04 1.40726E-04
P/A 4888 Ig-32 1 rs376799249 0.6676 -1.59 1.0 D 0.838 0.685 0.112648838833 gnomAD-3.1.2 5.26E-05 None None None None N None 4.83E-05 0 0 0 0 None 9.43E-05 0 7.35E-05 0 0
P/A 4888 Ig-32 1 rs376799249 0.6676 -1.59 1.0 D 0.838 0.685 0.112648838833 gnomAD-4.0.0 1.38821E-04 None None None None N None 2.66951E-05 0 None 0 0 None 6.25332E-05 0 1.80538E-04 0 8.00769E-05
P/R 4888 Ig-32 1 None 0.9489 None 1.0 D 0.877 0.683 0.215109475489 gnomAD-4.0.0 1.59147E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8582E-06 0 0
P/S 4888 Ig-32 1 None 0.9173 None 1.0 D 0.881 0.706 0.112648838833 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92678E-04 None 0 0 0 0 0
P/S 4888 Ig-32 1 None 0.9173 None 1.0 D 0.881 0.706 0.112648838833 gnomAD-4.0.0 6.57246E-06 None None None None N None 0 0 None 0 1.92678E-04 None 0 0 0 0 0
P/S 4981 Ig-33 1 rs1305431573 0.9531 None 1.0 D 0.792 0.752 0.657814710005 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 4981 Ig-33 1 rs1305431573 0.9531 None 1.0 D 0.792 0.752 0.657814710005 gnomAD-4.0.0 6.57246E-06 None None None None N None 2.41336E-05 0 None 0 0 None 0 0 0 0 0
P/A 5075 Ig-34 1 rs748837287 0.8272 -1.366 1.0 D 0.833 0.849 0.748558836882 gnomAD-2.1.1 4.77E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.01E-05 0
P/A 5075 Ig-34 1 rs748837287 0.8272 -1.366 1.0 D 0.833 0.849 0.748558836882 gnomAD-4.0.0 5.17204E-06 None None None None N None 0 0 None 0 0 None 1.9516E-05 0 6.11714E-06 0 0
P/L 5075 Ig-34 1 rs1553929816 0.9244 None 1.0 D 0.897 0.87 0.928938614015 gnomAD-4.0.0 7.07426E-07 None None None None N None 0 0 None 0 0 None 0 0 9.18285E-07 0 0
P/S 5075 Ig-34 1 None 0.9852 None 1.0 D 0.896 0.86 0.763806045514 gnomAD-4.0.0 1.72401E-06 None None None None N None 0 0 None 0 0 None 0 0 3.05857E-06 0 0
A/S 5261 Ig-36 1 None 0.3661 None 1.0 D 0.606 0.262 0.234412748748 gnomAD-4.0.0 6.86129E-07 None None None None N None 0 0 None 0 0 None 0 0 9.01677E-07 0 0
A/T 5261 Ig-36 1 rs1460264002 0.7075 -1.387 1.0 D 0.714 0.299 0.267299060538 gnomAD-2.1.1 7.2E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.58E-05 0
A/T 5261 Ig-36 1 rs1460264002 0.7075 -1.387 1.0 D 0.714 0.299 0.267299060538 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 4.41E-05 0 0
A/T 5261 Ig-36 1 rs1460264002 0.7075 -1.387 1.0 D 0.714 0.299 0.267299060538 gnomAD-4.0.0 3.72759E-06 None None None None N None 0 0 None 0 0 None 0 0 5.09739E-06 0 0
P/S 5357 Ig-37 1 rs1467703602 0.9828 -1.864 1.0 D 0.882 0.613 0.698733648705 gnomAD-2.1.1 4.26E-06 None None None None N None 0 0 None 0 5.63E-05 None 0 None 0 0 0
P/A 5450 Ig-38 1 rs763896243 0.3589 -1.491 0.998 D 0.804 0.626 0.699586999277 gnomAD-2.1.1 4.41E-06 None None None None N None 0 0 None 0 0 None 3.91E-05 None 0 0 0
P/A 5450 Ig-38 1 rs763896243 0.3589 -1.491 0.998 D 0.804 0.626 0.699586999277 gnomAD-4.0.0 1.39204E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.43659E-05 0
P/S 5450 Ig-38 1 None 0.8575 None 1.0 D 0.889 0.627 0.705942088615 gnomAD-4.0.0 6.96022E-07 None None None None N None 0 0 None 0 0 None 0 0 9.09149E-07 0 0
A/T 5543 Ig-39 1 rs1460498518 0.3578 -1.394 0.98 N 0.507 0.266 0.173771789658 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14863E-04 0 None 0 0 None 0 None 0 0 0
A/T 5543 Ig-39 1 rs1460498518 0.3578 -1.394 0.98 N 0.507 0.266 0.173771789658 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 5543 Ig-39 1 rs1460498518 0.3578 -1.394 0.98 N 0.507 0.266 0.173771789658 gnomAD-4.0.0 6.57445E-06 None None None None N None 2.41429E-05 0 None 0 0 None 0 0 0 0 0
P/A 5637 Ig-40 1 None 0.6468 None 1.0 D 0.833 0.501 0.673546118213 gnomAD-4.0.0 2.40064E-05 None None None None N None 0 0 None 0 0 None 0 0 2.625E-05 0 0
P/L 5637 Ig-40 1 rs749185334 0.8606 -0.24 1.0 D 0.871 0.522 0.838246210828 gnomAD-2.1.1 4.08E-06 None None None None N None 0 0 None 0 0 None 3.36E-05 None 0 0 0
P/L 5637 Ig-40 1 rs749185334 0.8606 -0.24 1.0 D 0.871 0.522 0.838246210828 gnomAD-4.0.0 2.75277E-06 None None None None N None 3.00625E-05 0 None 0 0 None 0 0 9.04431E-07 1.16885E-05 1.66678E-05
P/A 5730 Ig-41 1 None 0.7019 None 0.998 D 0.817 0.655 0.626855883447 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.93199E-04 None 0 0 0 0 0
P/A 5730 Ig-41 1 None 0.7019 None 0.998 D 0.817 0.655 0.626855883447 gnomAD-4.0.0 6.57557E-06 None None None None N None 0 0 None 0 1.93199E-04 None 0 0 0 0 0
P/L 5730 Ig-41 1 rs779187099 0.9016 -0.32 0.64 D 0.773 0.629 0.837822526163 gnomAD-2.1.1 4.21E-06 None None None None N None 6.52E-05 0 None 0 0 None 0 None 0 0 0
P/L 5730 Ig-41 1 rs779187099 0.9016 -0.32 0.64 D 0.773 0.629 0.837822526163 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/L 5730 Ig-41 1 rs779187099 0.9016 -0.32 0.64 D 0.773 0.629 0.837822526163 gnomAD-4.0.0 2.50317E-06 None None None None N None 4.0428E-05 0 None 0 0 None 0 1.6728E-04 0 0 0
P/A 5919 Ig-43 1 rs780414866 0.9288 -1.353 1.0 D 0.821 0.766 0.669649519912 gnomAD-2.1.1 1.24E-05 None None None None N None 0 8.85E-05 None 0 0 None 0 None 0 0 0
P/A 5919 Ig-43 1 rs780414866 0.9288 -1.353 1.0 D 0.821 0.766 0.669649519912 gnomAD-4.0.0 4.86145E-06 None None None None N None 0 6.96153E-05 None 0 0 None 0 0 0 0 0
P/L 5919 Ig-43 1 rs1275881697 0.9839 None 1.0 D 0.886 0.755 0.90829014345 gnomAD-4.0.0 3.24051E-06 None None None None N None 1.1542E-04 0 None 0 0 None 0 0 0 0 0
P/S 5919 Ig-43 1 rs780414866 0.9934 -1.648 1.0 D 0.885 0.78 0.67526397899 gnomAD-2.1.1 8.28E-06 None None None None N None 0 0 None 0 0 None 6.88E-05 None 0 0 0
P/S 5919 Ig-43 1 rs780414866 0.9934 -1.648 1.0 D 0.885 0.78 0.67526397899 gnomAD-4.0.0 3.24097E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.92406E-05 0
P/L 6012 Ig-44 1 None 0.8927 None 1.0 D 0.896 0.743 0.812414231654 gnomAD-4.0.0 1.38655E-06 None None None None N None 0 0 None 0 0 None 0 1.75747E-04 9.07146E-07 0 0
P/S 6012 Ig-44 1 None 0.959 None 1.0 D 0.883 0.754 0.658736925141 gnomAD-4.0.0 2.81545E-06 None None None None N None 0 0 None 0 0 None 0 0 3.65532E-06 0 0
P/T 6012 Ig-44 1 None 0.954 None 1.0 D 0.882 0.75 0.695824657773 gnomAD-4.0.0 7.03863E-07 None None None None N None 3.18634E-05 0 None 0 0 None 0 0 0 0 0
P/L 6105 Ig-45 1 None 0.6664 None 1.0 D 0.897 0.769 0.948956264298 gnomAD-4.0.0 1.59812E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86615E-06 0 0
P/A 6199 Ig-46 1 None 0.6681 None 0.996 D 0.811 0.635 0.675111477399 gnomAD-4.0.0 1.59492E-06 None None None None N None 0 0 None 0 2.775E-05 None 0 0 0 0 0
P/L 6199 Ig-46 1 rs758776829 0.8501 0.257 0.999 D 0.875 0.612 0.907606656126 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 6292 Ig-47 1 rs1180688317 0.9298 -1.925 0.987 D 0.834 0.765 0.633965432156 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
P/S 6292 Ig-47 1 rs1180688317 0.9298 -1.925 0.987 D 0.834 0.765 0.633965432156 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 6292 Ig-47 1 rs1180688317 0.9298 -1.925 0.987 D 0.834 0.765 0.633965432156 gnomAD-4.0.0 6.57436E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47059E-05 0 0
A/T 6385 Ig-48 1 rs1032273558 0.7946 -1.302 0.989 N 0.587 0.251 0.268660756437 gnomAD-2.1.1 4.09E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9E-06 0
A/T 6385 Ig-48 1 rs1032273558 0.7946 -1.302 0.989 N 0.587 0.251 0.268660756437 gnomAD-4.0.0 3.45984E-06 None None None None N None 0 0 None 0 0 None 0 0 4.54745E-06 0 0
A/V 6385 Ig-48 1 rs1560764364 0.7675 None 0.989 N 0.588 0.329 0.33835085245 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 6481 Ig-49 1 rs73038342 0.9699 -1.909 0.414 D 0.701 0.746 0.483670899158 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 6481 Ig-49 1 rs73038342 0.9699 -1.909 0.414 D 0.701 0.746 0.483670899158 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
P/T 6481 Ig-49 1 rs73038342 0.9661 -1.744 0.976 D 0.875 0.82 0.792433632955 gnomAD-2.1.1 8.18E-05 None None None None N None 0 0 None 0 0 None 6.52978E-04 None 0 9.49E-06 0
P/T 6481 Ig-49 1 rs73038342 0.9661 -1.744 0.976 D 0.875 0.82 0.792433632955 gnomAD-3.1.2 5.92E-05 None None None None N None 0 0 0 0 0 None 0 0 0 1.86567E-03 0
P/T 6481 Ig-49 1 rs73038342 0.9661 -1.744 0.976 D 0.875 0.82 0.792433632955 gnomAD-4.0.0 8.62227E-05 None None None None N None 0 0 None 0 0 None 0 1.67001E-04 2.89598E-05 1.13895E-03 3.23206E-05
P/Q 6574 Ig-50 1 None 0.9746 None 1.0 D 0.892 0.653 0.83602636732 gnomAD-4.0.0 1.67444E-06 None None None None N None 0 0 None 0 0 None 0 0 2.97115E-06 0 0
P/L 6667 Ig-51 1 rs2079519176 0.8709 None 1.0 D 0.902 0.657 0.91084523756 gnomAD-4.0.0 6.94337E-07 None None None None N None 0 0 None 0 2.53872E-05 None 0 0 0 0 0
P/Q 6667 Ig-51 1 None 0.9894 None 1.0 D 0.892 0.651 0.817946318196 gnomAD-4.0.0 6.94337E-07 None None None None N None 0 0 None 0 0 None 0 0 9.07711E-07 0 0
P/R 6667 Ig-51 1 None 0.991 None 1.0 D 0.905 0.661 0.863231483024 gnomAD-4.0.0 6.94337E-07 None None None None N None 0 0 None 0 0 None 0 0 9.07711E-07 0 0
P/S 6667 Ig-51 1 rs771421787 0.9387 -1.733 1.0 D 0.9 0.668 0.669504143626 gnomAD-2.1.1 8.68E-06 None None None None N None 0 0 None 0 0 None 7.65E-05 None 0 0 0
P/T 6667 Ig-51 1 rs771421787 0.9256 None 1.0 D 0.901 0.695 0.825518248999 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
P/T 6667 Ig-51 1 rs771421787 0.9256 None 1.0 D 0.901 0.695 0.825518248999 gnomAD-4.0.0 6.57419E-06 None None None None N None 0 6.55652E-05 None 0 0 None 0 0 0 0 0
P/H 6761 Ig-52 1 None 0.9969 None 1.0 D 0.823 0.851 0.926979556658 gnomAD-4.0.0 7.38886E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.48012E-05 0
P/L 6761 Ig-52 1 None 0.905 None 1.0 D 0.854 0.837 0.946790031181 gnomAD-4.0.0 7.38886E-07 None None None None N None 0 0 None 0 0 None 0 0 9.44275E-07 0 0
P/S 6761 Ig-52 1 None 0.9755 None 1.0 D 0.873 0.834 0.807443498692 gnomAD-4.0.0 6.63649E-06 None None None None N None 0 0 None 0 0 None 0 0 8.48327E-06 0 0
P/T 6761 Ig-52 1 None 0.9599 None 1.0 D 0.868 0.83 0.910513559645 gnomAD-4.0.0 7.37388E-07 None None None None N None 0 3.56328E-05 None 0 0 None 0 0 0 0 0
A/P 6948 Ig-54 1 None 0.6101 None 1.0 N 0.85 0.389 0.223146558224 gnomAD-4.0.0 6.99022E-07 None None None None N None 0 0 None 0 0 None 1.90534E-05 0 0 0 0
A/S 6948 Ig-54 1 None 0.4048 None 0.997 N 0.6 0.28 0.218112801441 gnomAD-4.0.0 6.99023E-07 None None None None N None 0 0 None 0 2.55689E-05 None 0 0 0 0 0
A/T 6948 Ig-54 1 rs147210608 0.7171 -1.098 0.977 N 0.441 0.288 None gnomAD-2.1.1 4.57E-05 None None None None N None 0 1.23854E-04 None 0 0 None 1.13054E-04 None 4.17E-05 3.29E-05 0
A/T 6948 Ig-54 1 rs147210608 0.7171 -1.098 0.977 N 0.441 0.288 None gnomAD-3.1.2 3.95E-05 None None None None N None 2.42E-05 6.55E-05 0 0 0 None 9.44E-05 0 4.41E-05 0 0
A/T 6948 Ig-54 1 rs147210608 0.7171 -1.098 0.977 N 0.441 0.288 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
A/T 6948 Ig-54 1 rs147210608 0.7171 -1.098 0.977 N 0.441 0.288 None gnomAD-4.0.0 2.46414E-05 None None None None N None 1.35377E-05 7.06739E-05 None 0 0 None 6.34115E-05 0 2.15163E-05 3.44598E-05 3.28407E-05
P/S 7044 Ig-55 1 rs773899102 0.9519 -1.631 0.322 D 0.675 0.754 0.477685322099 gnomAD-2.1.1 8.13E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.8E-05 0
P/S 7044 Ig-55 1 rs773899102 0.9519 -1.631 0.322 D 0.675 0.754 0.477685322099 gnomAD-4.0.0 6.85243E-06 None None None None N None 0 0 None 0 0 None 0 0 9.00607E-06 0 0
P/H 7137 Ig-56 1 None 0.9856 None 1.0 D 0.858 0.655 0.766497784903 gnomAD-4.0.0 7.00313E-07 None None None None N None 0 0 None 0 0 None 0 0 9.10692E-07 0 0
P/L 7137 Ig-56 1 rs886043853 0.6924 None 1.0 D 0.882 0.659 0.827666919745 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/L 7137 Ig-56 1 rs886043853 0.6924 None 1.0 D 0.882 0.659 0.827666919745 gnomAD-4.0.0 3.16453E-06 None None None None N None 1.3614E-05 0 None 0 0 None 0 0 1.71517E-06 2.38203E-05 0
P/R 7137 Ig-56 1 rs886043853 0.9779 -0.987 1.0 D 0.881 0.649 0.766497784903 gnomAD-2.1.1 4.63E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.9E-06 0
P/R 7137 Ig-56 1 rs886043853 0.9779 -0.987 1.0 D 0.881 0.649 0.766497784903 gnomAD-4.0.0 2.80125E-06 None None None None N None 0 0 None 0 0 None 0 0 3.64277E-06 0 0
A/S 7230 Ig-57 1 rs1458297684 0.3461 None 0.994 N 0.527 0.355 0.335164054921 gnomAD-4.0.0 6.00161E-06 None None None None I None 0 0 None 0 0 None 0 0 6.56251E-06 0 0
A/V 7230 Ig-57 1 rs761223583 0.3868 -0.2 0.733 N 0.251 0.386 0.473931330248 gnomAD-2.1.1 5.29E-05 None None None None I None 0 2.63204E-04 None 0 0 None 0 None 0 3.61E-05 0
A/V 7230 Ig-57 1 rs761223583 0.3868 -0.2 0.733 N 0.251 0.386 0.473931330248 gnomAD-3.1.2 1.97E-05 None None None None I None 2.41E-05 6.55E-05 0 0 0 None 0 0 1.47E-05 0 0
A/V 7230 Ig-57 1 rs761223583 0.3868 -0.2 0.733 N 0.251 0.386 0.473931330248 gnomAD-4.0.0 2.73078E-05 None None None None I None 1.3379E-05 1.84088E-04 None 0 0 None 0 0 2.71518E-05 0 0
P/L 7419 Ig-59 1 None 0.8761 None 0.998 D 0.873 0.73 0.945451758466 gnomAD-4.0.0 1.59608E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86752E-06 0 0
P/S 7419 Ig-59 1 rs1486377872 0.9692 -1.619 0.992 D 0.842 0.801 0.775873742492 gnomAD-2.1.1 8.09E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
P/S 7419 Ig-59 1 rs1486377872 0.9692 -1.619 0.992 D 0.842 0.801 0.775873742492 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 7419 Ig-59 1 rs1486377872 0.9692 -1.619 0.992 D 0.842 0.801 0.775873742492 gnomAD-4.0.0 6.20417E-06 None None None None N None 0 0 None 0 0 None 0 0 8.48427E-06 0 0
P/R 7515 Ig-60 1 None 0.9861 None 1.0 D 0.889 0.577 0.895621291542 gnomAD-4.0.0 2.40065E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
P/S 7608 Ig-61 1 None 0.9743 None 1.0 D 0.871 0.704 0.695117004628 gnomAD-4.0.0 1.64723E-06 None None None None N None 0 0 None 0 0 None 1.93949E-05 0 0 0 0
P/S 7702 Ig-62 1 None 0.9908 None 1.0 D 0.876 0.801 0.709197088356 gnomAD-4.0.0 7.00126E-07 None None None None N None 3.16496E-05 0 None 0 0 None 0 0 0 0 0
P/L 7795 Ig-63 1 None 0.9372 None 1.0 D 0.884 0.717 0.898999087379 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/S 7795 Ig-63 1 rs1164633288 0.9768 -2.287 1.0 D 0.888 0.799 0.699004069071 gnomAD-2.1.1 4.07E-06 None None None None N None 0 2.92E-05 None 0 0 None 0 None 0 0 0
P/S 7795 Ig-63 1 rs1164633288 0.9768 -2.287 1.0 D 0.888 0.799 0.699004069071 gnomAD-4.0.0 3.21027E-06 None None None None N None 0 2.30574E-05 None 0 0 None 0 0 2.88719E-06 0 0
A/E 7889 Ig-64 1 None 0.9867 None 0.978 N 0.708 0.449 0.417208245017 gnomAD-4.0.0 2.06755E-06 None None None None N None 0 0 None 0 0 None 0 0 2.713E-06 0 0
A/S 7889 Ig-64 1 rs777855676 0.4192 -1.364 0.928 N 0.585 0.241 0.253726318573 gnomAD-2.1.1 4.15E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.17E-06 0
A/S 7889 Ig-64 1 rs777855676 0.4192 -1.364 0.928 N 0.585 0.241 0.253726318573 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/S 7889 Ig-64 1 rs777855676 0.4192 -1.364 0.928 N 0.585 0.241 0.253726318573 gnomAD-4.0.0 3.11945E-06 None None None None N None 0 0 None 0 0 None 0 0 4.26003E-06 0 0
A/T 7889 Ig-64 1 rs777855676 0.8153 -1.325 0.928 N 0.668 0.291 0.285316908763 gnomAD-2.1.1 6.64E-05 None None None None N None 0 0 None 0 0 None 5.52219E-04 None 0 0 0
A/T 7889 Ig-64 1 rs777855676 0.8153 -1.325 0.928 N 0.668 0.291 0.285316908763 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07555E-04 0
A/T 7889 Ig-64 1 rs777855676 0.8153 -1.325 0.928 N 0.668 0.291 0.285316908763 gnomAD-4.0.0 4.05528E-05 None None None None N None 0 0 None 0 0 None 0 0 8.52006E-07 7.14924E-04 0
A/V 7889 Ig-64 1 None 0.8077 None 0.928 N 0.623 0.408 0.37762505005 gnomAD-4.0.0 6.89185E-07 None None None None N None 0 0 None 0 0 None 0 0 9.04332E-07 0 0
P/A 7985 Ig-65 1 None 0.666 None 1.0 D 0.839 0.678 0.642681104822 gnomAD-4.0.0 1.59403E-06 None None None None N None 0 2.28843E-05 None 0 0 None 0 0 0 0 0
P/L 7985 Ig-65 1 rs746422101 0.8948 -0.166 1.0 D 0.893 0.625 0.9156675434 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/L 7985 Ig-65 1 rs746422101 0.8948 -0.166 1.0 D 0.893 0.625 0.9156675434 gnomAD-4.0.0 2.05414E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70038E-06 0 0
P/L 8078 Ig-66 1 rs1419971092 0.8384 None 1.0 D 0.898 0.783 0.921701612673 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.93199E-04 None 0 0 0 0 0
P/Q 8078 Ig-66 1 None 0.9911 None 1.0 D 0.884 0.781 0.861147461873 gnomAD-4.0.0 1.62111E-06 None None None None N None 0 0 None 0 0 None 0 0 2.90591E-06 0 0
P/R 8078 Ig-66 1 rs1419971092 0.9901 None 1.0 D 0.894 0.773 0.882996757023 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.93199E-04 None 0 0 0 0 0
P/R 8078 Ig-66 1 rs1419971092 0.9901 None 1.0 D 0.894 0.773 0.882996757023 gnomAD-4.0.0 6.57704E-06 None None None None N None 0 0 None 0 1.93199E-04 None 0 0 0 0 0
P/S 8078 Ig-66 1 rs750589456 0.9564 None 1.0 D 0.897 0.768 0.715476549107 gnomAD-4.0.0 1.37894E-06 None None None None N None 0 0 None 0 2.54207E-05 None 0 0 0 1.1805E-05 0
P/T 8078 Ig-66 1 rs750589456 0.9398 -1.488 1.0 D 0.896 0.783 0.858583215259 gnomAD-2.1.1 4.3E-06 None None None None N None 0 0 None 0 5.94E-05 None 0 None 0 0 0
P/T 8078 Ig-66 1 rs750589456 0.9398 -1.488 1.0 D 0.896 0.783 0.858583215259 gnomAD-4.0.0 2.0684E-06 None None None None N None 0 0 None 0 7.62621E-05 None 0 0 0 0 0
A/V 8171 Ig-67 1 rs755340155 0.7317 -0.275 0.998 N 0.649 0.395 None gnomAD-2.1.1 7.17E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
A/V 8171 Ig-67 1 rs755340155 0.7317 -0.275 0.998 N 0.649 0.395 None gnomAD-3.1.2 1.97E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
A/V 8171 Ig-67 1 rs755340155 0.7317 -0.275 0.998 N 0.649 0.395 None gnomAD-4.0.0 4.05981E-06 None None None None N None 5.24256E-05 0 None 0 0 None 0 0 0 0 3.40275E-05
P/A 8264 Ig-68 1 None 0.7427 None 1.0 D 0.818 0.638 0.74833783201 gnomAD-4.0.0 1.63066E-06 None None None None N None 0 0 None 4.84496E-05 0 None 0 0 0 0 0
P/L 8264 Ig-68 1 rs1235369035 0.9327 0.033 1.0 D 0.865 0.647 0.905832655978 gnomAD-2.1.1 8.38E-06 None None None None N None 0 0 None 0 0 None 3.42E-05 None 0 9.02E-06 0
P/L 8264 Ig-68 1 rs1235369035 0.9327 0.033 1.0 D 0.865 0.647 0.905832655978 gnomAD-4.0.0 4.14748E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70866E-06 2.34775E-05 1.66706E-05
P/L 8456 Ig-70 1 rs1308450887 0.9212 None 0.992 D 0.757 0.733 0.834275830499 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 8456 Ig-70 1 rs1308450887 0.9212 None 0.992 D 0.757 0.733 0.834275830499 gnomAD-4.0.0 6.57099E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47011E-05 0 0
P/R 8456 Ig-70 1 None 0.9911 None 0.631 D 0.674 0.693 0.663271509172 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/T 8456 Ig-70 1 None 0.9586 None 0.936 D 0.689 0.69 0.676758004843 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/H 8549 Ig-71 1 rs774351461 0.9961 -1.608 1.0 D 0.879 0.83 0.877040243179 gnomAD-2.1.1 5.34E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.13999E-04 1.62813E-04
P/H 8549 Ig-71 1 rs774351461 0.9961 -1.608 1.0 D 0.879 0.83 0.877040243179 gnomAD-3.1.2 2.63E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 4.41E-05 0 0
P/H 8549 Ig-71 1 rs774351461 0.9961 -1.608 1.0 D 0.879 0.83 0.877040243179 gnomAD-4.0.0 8.6227E-05 None None None None N None 5.40205E-05 1.83043E-05 None 0 0 None 0 0 1.07783E-04 0 9.82157E-05
P/L 8549 Ig-71 1 None 0.8838 None 1.0 D 0.911 0.852 0.917192438884 gnomAD-4.0.0 1.40334E-06 None None None None N None 0 0 None 0 0 None 3.9142E-05 0 0 0 0
P/S 8549 Ig-71 1 rs536374359 0.9564 -1.616 1.0 D 0.907 0.853 0.686436817987 gnomAD-2.1.1 3.66E-05 None None None None N None 0 0 None 0 4.97937E-04 None 0 None 0 0 0
P/S 8549 Ig-71 1 rs536374359 0.9564 -1.616 1.0 D 0.907 0.853 0.686436817987 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 5.78258E-04 None 0 0 0 0 4.78011E-04
P/S 8549 Ig-71 1 rs536374359 0.9564 -1.616 1.0 D 0.907 0.853 0.686436817987 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
P/S 8549 Ig-71 1 rs536374359 0.9564 -1.616 1.0 D 0.907 0.853 0.686436817987 gnomAD-4.0.0 2.34722E-05 None None None None N None 0 0 None 0 8.28424E-04 None 0 0 0 0 1.63736E-05
P/H 8643 Ig-72 1 rs746681999 0.9954 None 1.0 D 0.846 0.791 0.844449701782 gnomAD-4.0.0 6.90654E-07 None None None None N None 0 0 None 0 0 None 0 0 9.04084E-07 0 0
P/R 8643 Ig-72 1 rs746681999 0.9909 -0.852 1.0 D 0.872 0.779 0.844449701782 gnomAD-2.1.1 4.21E-06 None None None None N None 0 0 None 0 0 None 0 None 4.75E-05 0 0
P/R 8643 Ig-72 1 rs746681999 0.9909 -0.852 1.0 D 0.872 0.779 0.844449701782 gnomAD-4.0.0 1.72663E-05 None None None None N None 0 0 None 0 0 None 1.88416E-05 0 2.1698E-05 0 0
P/S 8643 Ig-72 1 rs754532440 0.9714 -1.842 1.0 D 0.895 0.779 0.658399546983 gnomAD-2.1.1 8.42E-06 None None None None N None 0 0 None 0 0 None 7.18E-05 None 0 0 0
P/S 8643 Ig-72 1 rs754532440 0.9714 -1.842 1.0 D 0.895 0.779 0.658399546983 gnomAD-4.0.0 1.79559E-05 None None None None N None 0 0 None 0 5.05382E-05 None 0 5.50257E-04 1.80813E-06 2.03082E-04 3.35255E-05
P/L 8736 Ig-73 1 rs1444367941 0.5805 None 1.0 D 0.879 0.68 0.920603051264 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 8736 Ig-73 1 rs777166872 0.8325 None 1.0 D 0.893 0.732 0.723536994813 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07727E-04 0
P/S 8736 Ig-73 1 rs777166872 0.8325 None 1.0 D 0.893 0.732 0.723536994813 gnomAD-4.0.0 1.2548E-06 None None None None N None 0 0 None 0 0 None 0 0 8.55835E-07 1.13253E-05 0
P/T 8736 Ig-73 1 rs777166872 0.7676 -2.077 1.0 D 0.888 0.719 0.859303954879 gnomAD-2.1.1 1.26E-05 None None None None N None 0 0 None 0 0 None 3.59E-05 None 0 9.13E-06 1.74216E-04
P/T 8736 Ig-73 1 rs777166872 0.7676 -2.077 1.0 D 0.888 0.719 0.859303954879 gnomAD-4.0.0 2.77438E-06 None None None None N None 0 0 None 0 0 None 0 0 9.08726E-07 2.39567E-05 1.6822E-05
A/E 8830 Ig-74 1 None 0.9763 None 1.0 N 0.809 0.34 0.42828666871 gnomAD-4.0.0 6.86803E-07 None None None None N None 0 0 None 0 2.5222E-05 None 0 0 0 0 0
A/T 8830 Ig-74 1 rs1358888602 0.5377 -1.391 1.0 N 0.722 0.285 0.244539031024 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 6.42674E-04 None 0 None 0 0 0
A/T 8830 Ig-74 1 rs1358888602 0.5377 -1.391 1.0 N 0.722 0.285 0.244539031024 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92678E-04 None 0 0 0 0 0
A/T 8830 Ig-74 1 rs1358888602 0.5377 -1.391 1.0 N 0.722 0.285 0.244539031024 gnomAD-4.0.0 6.57315E-06 None None None None N None 0 0 None 0 1.92678E-04 None 0 0 0 0 0
A/V 8830 Ig-74 1 rs976129365 0.5725 -0.557 1.0 N 0.673 0.332 0.391930172978 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
A/V 8830 Ig-74 1 rs976129365 0.5725 -0.557 1.0 N 0.673 0.332 0.391930172978 gnomAD-4.0.0 6.86803E-07 None None None None N None 3.02407E-05 0 None 0 0 None 0 0 0 0 0
P/L 9019 Ig-76 1 None 0.7558 None 0.998 D 0.885 0.76 0.907006725545 gnomAD-4.0.0 1.37006E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80058E-06 0 0
P/R 9019 Ig-76 1 None 0.9842 None 0.999 D 0.905 0.815 0.85697642895 gnomAD-4.0.0 6.85028E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00289E-07 0 0
P/S 9019 Ig-76 1 rs2076880929 0.9402 None 0.995 D 0.847 0.824 0.645952563013 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 9019 Ig-76 1 rs2076880929 0.9402 None 0.995 D 0.847 0.824 0.645952563013 gnomAD-4.0.0 2.56768E-06 None None None None N None 3.38467E-05 0 None 0 0 None 0 0 0 0 0
P/L 9205 Ig-78 1 rs758238716 0.8673 0.051 1.0 D 0.884 0.774 0.914536145376 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 9.44E-05 0 0 0 0
P/L 9205 Ig-78 1 rs758238716 0.8673 0.051 1.0 D 0.884 0.774 0.914536145376 gnomAD-4.0.0 2.4805E-06 None None None None N None 0 0 None 0 0 None 3.12764E-05 0 1.69626E-06 0 0
P/S 9205 Ig-78 1 rs1216622524 0.946 None 1.0 D 0.895 0.801 0.689703077716 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 9205 Ig-78 1 rs1216622524 0.946 None 1.0 D 0.895 0.801 0.689703077716 gnomAD-4.0.0 1.24025E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69629E-06 0 0
P/T 9205 Ig-78 1 rs1216622524 0.9255 None 1.0 D 0.891 0.821 0.829472311377 gnomAD-4.0.0 6.84692E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.6575E-05
P/L 9301 Ig-79 1 rs372056758 0.8309 -0.092 1.0 D 0.892 0.815 None gnomAD-2.1.1 4.1E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.01E-06 0
P/L 9301 Ig-79 1 rs372056758 0.8309 -0.092 1.0 D 0.892 0.815 None gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 9397 Ig-80 1 rs1359908699 0.7946 -0.167 1.0 None 0.887 0.572 0.830294410965 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
P/L 9397 Ig-80 1 rs1359908699 0.7946 -0.167 1.0 None 0.887 0.572 0.830294410965 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 9397 Ig-80 1 rs1359908699 0.7946 -0.167 1.0 None 0.887 0.572 0.830294410965 gnomAD-4.0.0 6.5735E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46994E-05 0 0
P/S 9397 Ig-80 1 rs1446166655 0.9195 -2.147 1.0 None 0.907 0.558 0.68224456972 gnomAD-2.1.1 3.18E-05 None None None None N None 0 1.17924E-03 None 0 0 None 0 None 0 0 0
P/S 9397 Ig-80 1 rs1446166655 0.9195 -2.147 1.0 None 0.907 0.558 0.68224456972 gnomAD-4.0.0 1.593E-06 None None None None N None 0 2.28707E-05 None 0 0 None 0 0 0 0 0
P/R 9493 Ig-81 1 None 0.9944 None 1.0 None 0.916 0.813 0.718972263718 gnomAD-4.0.0 4.79011E-06 None None None None N None 0 0 None 0 0 None 0 0 8.60259E-06 0 0
P/S 9493 Ig-81 1 None 0.9795 None 1.0 None 0.953 0.733 0.666594129058 gnomAD-4.0.0 1.59664E-06 None None None None N None 0 0 None 4.77054E-05 0 None 0 0 0 0 0
P/T 9493 Ig-81 1 rs778959524 0.9681 0.148 1.0 None 0.951 0.723 0.691255109571 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
P/T 9493 Ig-81 1 rs778959524 0.9681 0.148 1.0 None 0.951 0.723 0.691255109571 gnomAD-4.0.0 3.1933E-06 None None None None N None 0 0 None 0 0 None 0 2.41663E-04 0 0 3.03067E-05
P/R 9590 Ig-82 1 rs867410935 0.9849 -0.706 1.0 None 0.875 0.609 0.618865024872 gnomAD-2.1.1 4.16E-06 None None None None N None 0 3.06E-05 None 0 0 None 0 None 0 0 0
P/R 9590 Ig-82 1 rs867410935 0.9849 -0.706 1.0 None 0.875 0.609 0.618865024872 gnomAD-4.0.0 1.6461E-06 None None None None N None 0 2.37903E-05 None 0 0 None 0 0 0 0 0
L/V 9698 Ig-83 1 None 0.376 None 0.939 None 0.546 0.173 0.573031010871 gnomAD-4.0.0 3.18886E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72528E-06 0 0
V/A 9900 Ig-84 1 None 0.9606 None 0.892 None 0.506 0.431 0.672779776643 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/I 9900 Ig-84 1 rs2075588711 0.1084 None 0.025 None 0.269 0.124 0.422040124859 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 9900 Ig-84 1 rs2075588711 0.1084 None 0.025 None 0.269 0.124 0.422040124859 gnomAD-4.0.0 6.44375E-06 None None None None I None 6.78702E-05 0 None 0 0 None 0 0 0 0 2.85649E-05
P/T 9989 Ig-85 1 rs1553877891 0.5462 None 0.98 None 0.525 0.646 0.780941640523 gnomAD-4.0.0 8.21707E-06 None None None None N None 0 0 None 0 2.51991E-05 None 0 1.7343E-04 9.00135E-06 0 0
V/L 13780 Ig-88 1 None 0.5204 None 0.994 N 0.475 0.288 0.388174495139 gnomAD-4.0.0 1.72771E-06 None None None None N None 0 0 None 5.38329E-05 0 None 0 0 0 0 0
V/A 13965 Ig-90 1 None 0.5101 None 0.029 N 0.115 0.128 0.411665641125 gnomAD-4.0.0 1.36897E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99693E-07 1.15996E-05 0
V/F 13965 Ig-90 1 rs1311645939 0.9284 -1.166 0.974 D 0.444 0.274 0.686837661534 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.91E-05 None 0 0 None 0 None 0 0 0
V/F 13965 Ig-90 1 rs1311645939 0.9284 -1.166 0.974 D 0.444 0.274 0.686837661534 gnomAD-4.0.0 1.59282E-06 None None None None N None 0 2.28749E-05 None 0 0 None 0 0 0 0 0
V/G 13965 Ig-90 1 rs878854306 0.789 -1.752 0.728 D 0.375 0.29 0.715243340896 gnomAD-2.1.1 1.21E-05 None None None None N None 0 8.72E-05 None 0 0 None 0 None 0 0 0
V/G 13965 Ig-90 1 rs878854306 0.789 -1.752 0.728 D 0.375 0.29 0.715243340896 gnomAD-4.0.0 5.5791E-06 None None None None N None 0 1.5005E-04 None 0 0 None 0 0 0 0 0
L/F 14054 Ig-91 1 rs1221996833 0.6664 None 0.989 N 0.456 0.312 0.520373764981 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/F 14054 Ig-91 1 rs1221996833 0.6664 None 0.989 N 0.456 0.312 0.520373764981 gnomAD-4.0.0 6.5786E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47124E-05 0 0
L/P 14054 Ig-91 1 None 0.7324 None 0.998 N 0.633 0.476 0.795030053833 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
L/R 14054 Ig-91 1 None 0.7738 None 0.994 N 0.585 0.468 0.822958799421 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 14319 Ig-94 1 None 0.9236 None 0.976 D 0.524 0.48 0.763395407181 gnomAD-4.0.0 1.36924E-06 None None None None I None 0 0 None 0 0 None 0 0 8.9976E-07 1.16255E-05 0
L/I 14408 Ig-95 1 rs767777694 0.1573 -0.59 0.122 D 0.229 0.386 0.397691132334 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
L/P 14497 Ig-96 1 None 0.7924 None 1.0 D 0.773 0.611 0.872922419221 gnomAD-4.0.0 1.67021E-06 None None None None N None 0 0 None 0 2.82294E-05 None 0 0 0 0 0
P/A 14586 Ig-97 1 rs2059766641 0.1769 None 0.98 D 0.635 0.56 0.564208378351 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/A 14586 Ig-97 1 rs2059766641 0.1769 None 0.98 D 0.635 0.56 0.564208378351 gnomAD-4.0.0 5.17106E-06 None None None None N None 0 0 None 0 0 None 0 0 9.62015E-06 0 0
P/T 14586 Ig-97 1 None 0.2427 None 0.98 D 0.69 0.561 0.761402108219 gnomAD-4.0.0 1.60865E-06 None None None None N None 0 0 None 0 0 None 1.97714E-05 0 0 0 0
I/T 14675 Ig-98 1 None 0.9342 None 0.999 D 0.629 0.433 0.577140404891 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 1.01626E-03 None 0 0 None 0 0 0 0 0
I/V 14675 Ig-98 1 rs1384628153 0.2323 None 0.985 N 0.32 0.192 0.427368086475 gnomAD-4.0.0 2.0558E-06 None None None None N None 0 0 None 3.83818E-05 0 None 0 0 1.80004E-06 0 0
G/D 14765 Ig-99 1 rs772788193 0.516 -0.264 0.999 N 0.581 0.434 0.453588565359 gnomAD-2.1.1 1.21E-05 None None None None I None 0 8.72E-05 None 0 0 None 0 None 0 0 0
G/D 14765 Ig-99 1 rs772788193 0.516 -0.264 0.999 N 0.581 0.434 0.453588565359 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/D 14765 Ig-99 1 rs772788193 0.516 -0.264 0.999 N 0.581 0.434 0.453588565359 gnomAD-4.0.0 5.13011E-06 None None None None I None 1.69291E-05 1.69601E-05 None 0 0 None 0 0 4.79187E-06 0 0
G/S 14765 Ig-99 1 None 0.1198 None 0.905 N 0.52 0.204 0.343560092441 gnomAD-4.0.0 1.5935E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.0292E-05
G/V 14765 Ig-99 1 rs772788193 0.313 -0.175 0.999 N 0.702 0.467 0.63538471256 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
G/V 14765 Ig-99 1 rs772788193 0.313 -0.175 0.999 N 0.702 0.467 0.63538471256 gnomAD-4.0.0 1.59337E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86225E-06 0 0
V/A 14853 Ig-100 1 rs1478720233 0.4474 -1.669 0.543 N 0.37 0.218 0.359763055319 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 5.61E-05 None 0 None 0 0 0
V/F 14853 Ig-100 1 rs753457792 0.8 None 0.999 N 0.715 0.355 0.62907203384 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/F 14853 Ig-100 1 rs753457792 0.8 None 0.999 N 0.715 0.355 0.62907203384 gnomAD-4.0.0 6.58172E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47245E-05 0 0
V/G 14853 Ig-100 1 None 0.7873 None 0.997 N 0.634 0.377 0.64568061723 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
V/I 14853 Ig-100 1 rs753457792 0.1555 -0.662 0.987 N 0.582 0.24 0.336155897331 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
V/M 14942 Ig-101 1 rs786205391 0.3506 None 0.998 D 0.672 0.324 0.661726622693 gnomAD-4.0.0 6.90904E-07 None None None None N None 0 0 None 0 0 None 0 0 9.05525E-07 0 0
A/G 15031 Ig-102 1 rs780981695 0.2446 -1.052 0.994 D 0.507 0.627 0.664964341062 gnomAD-4.0.0 6.85521E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.16469E-05 0
A/P 15031 Ig-102 1 rs2058306842 0.2 None 0.999 N 0.586 0.335 0.540153309661 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07297E-04 0
A/P 15031 Ig-102 1 rs2058306842 0.2 None 0.999 N 0.586 0.335 0.540153309661 gnomAD-4.0.0 6.58614E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07297E-04 0
A/V 15031 Ig-102 1 None 0.1745 None 0.733 D 0.341 0.463 0.552575064031 gnomAD-4.0.0 2.74208E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70098E-06 0 1.6608E-05
A/T 15120 Ig-103 1 rs773442807 0.4352 -0.925 0.999 D 0.689 0.378 0.394384168047 gnomAD-2.1.1 8.15E-06 None None None None N None 0 5.91E-05 None 0 0 None 0 None 0 0 0
A/T 15120 Ig-103 1 rs773442807 0.4352 -0.925 0.999 D 0.689 0.378 0.394384168047 gnomAD-4.0.0 3.19856E-06 None None None None N None 0 4.63628E-05 None 0 0 None 0 0 0 0 0
L/F 15208 Ig-104 1 rs1339878633 0.8491 -1.626 0.999 D 0.774 0.398 0.74166409102 gnomAD-2.1.1 4.1E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.68862E-04
L/F 15208 Ig-104 1 rs1339878633 0.8491 -1.626 0.999 D 0.774 0.398 0.74166409102 gnomAD-4.0.0 2.74473E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70143E-06 0 1.66262E-05
L/F 15302 Ig-105 1 rs1229771826 0.456 None 1.0 D 0.649 0.416 0.735594876934 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/F 15302 Ig-105 1 rs1229771826 0.456 None 1.0 D 0.649 0.416 0.735594876934 gnomAD-4.0.0 1.24573E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69868E-06 0 0
T/I 15391 Ig-106 1 rs775807236 0.3746 -0.019 0.993 D 0.571 0.558 0.593515057505 gnomAD-2.1.1 4.11E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.07E-06 0
T/I 15391 Ig-106 1 rs775807236 0.3746 -0.019 0.993 D 0.571 0.558 0.593515057505 gnomAD-4.0.0 6.19711E-06 None None None None N None 0 0 None 0 0 None 0 7.01016E-04 2.71169E-06 0 3.33778E-05
T/R 15391 Ig-106 1 None 0.5701 None 0.997 D 0.547 0.553 0.65667953858 gnomAD-4.0.0 1.37714E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80779E-06 0 0
V/L 15480 Ig-107 1 rs777031546 0.4693 -0.041 0.489 N 0.575 0.345 0.535537035517 gnomAD-2.1.1 8.29E-06 None None None None N None 1.30736E-04 0 None 0 0 None 0 None 0 0 0
V/L 15480 Ig-107 1 rs777031546 0.4693 -0.041 0.489 N 0.575 0.345 0.535537035517 gnomAD-4.0.0 1.60893E-06 None None None None N None 5.83567E-05 0 None 0 0 None 0 0 0 0 0
P/Q 15568 Ig-108 1 None 0.9866 None 1.0 D 0.88 0.673 0.598035270499 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 15568 Ig-108 1 rs561728671 0.9383 -2.131 1.0 D 0.89 0.667 0.569173210356 gnomAD-2.1.1 3.26E-05 None None None None N None 0 8.81E-05 None 0 0 None 0 None 0 4.5E-05 0
P/S 15568 Ig-108 1 rs561728671 0.9383 -2.131 1.0 D 0.89 0.667 0.569173210356 gnomAD-3.1.2 1.32E-05 None None None None N None 0 1.3132E-04 0 0 0 None 0 0 0 0 0
P/S 15568 Ig-108 1 rs561728671 0.9383 -2.131 1.0 D 0.89 0.667 0.569173210356 gnomAD-4.0.0 4.22716E-05 None None None None N None 0 1.50946E-04 None 0 0 None 0 0 4.83776E-05 0 3.21802E-05
P/A 16955 Ig-111 1 None 0.7409 None 1.0 D 0.834 0.766 0.662692292153 gnomAD-4.0.0 6.85007E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99973E-07 0 0
P/T 16955 Ig-111 1 rs757101775 0.9571 -1.855 1.0 D 0.893 0.77 0.694831530802 gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 3.3E-05 None 0 0 0
P/T 16955 Ig-111 1 rs757101775 0.9571 -1.855 1.0 D 0.893 0.77 0.694831530802 gnomAD-4.0.0 1.37001E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99973E-07 1.16271E-05 0
V/I 17251 Ig-112 1 rs1304051107 0.1331 -0.788 0.016 N 0.301 0.068 0.416833835346 gnomAD-2.1.1 4.13E-06 None None None None I None 0 2.93E-05 None 0 0 None 0 None 0 0 0
V/I 17251 Ig-112 1 rs1304051107 0.1331 -0.788 0.016 N 0.301 0.068 0.416833835346 gnomAD-4.0.0 2.06186E-06 None None None None I None 0 4.51182E-05 None 0 0 None 0 0 9.02377E-07 0 0
S/C 17677 Ig-113 1 None 0.2482 None 1.0 D 0.532 0.393 0.633926072375 gnomAD-4.0.0 1.59294E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43308E-05 0
R/C 17968 Ig-114 1 rs776785175 0.289 -0.356 0.999 N 0.215 0.354 0.670247443365 gnomAD-2.1.1 2.22E-05 None None None None I None 0 6.52E-05 None 0 0 None 3.86E-05 None 0 1.93E-05 0
R/C 17968 Ig-114 1 rs776785175 0.289 -0.356 0.999 N 0.215 0.354 0.670247443365 gnomAD-4.0.0 9.05292E-06 None None None None I None 3.08471E-05 4.84379E-05 None 0 0 None 0 0 8.1839E-06 1.21862E-05 0
R/H 17968 Ig-114 1 rs200100660 0.1479 -0.713 0.998 N 0.207 0.29 None gnomAD-2.1.1 8.76E-05 None None None None I None 2.73112E-04 0 None 0 0 None 0 None 5E-05 1.43442E-04 0
R/H 17968 Ig-114 1 rs200100660 0.1479 -0.713 0.998 N 0.207 0.29 None gnomAD-3.1.2 9.22E-05 None None None None I None 1.9348E-04 0 0 0 0 None 0 0 8.83E-05 0 0
R/H 17968 Ig-114 1 rs200100660 0.1479 -0.713 0.998 N 0.207 0.29 None gnomAD-4.0.0 1.1059E-04 None None None None I None 1.75771E-04 0 None 0 9.03669E-05 None 3.20205E-05 5.01672E-04 1.29995E-04 0 3.25415E-05
R/S 17968 Ig-114 1 rs776785175 0.6175 None 0.911 N 0.315 0.223 0.396794106654 gnomAD-3.1.2 6.59E-06 None None None None I None 0 0 0 0 0 None 0 3.16456E-03 0 0 0
R/S 17968 Ig-114 1 rs776785175 0.6175 None 0.911 N 0.315 0.223 0.396794106654 gnomAD-4.0.0 6.58033E-06 None None None None I None 0 0 None 0 0 None 0 3.40136E-03 0 0 0
I/T 18382 Ig-115 1 None 0.1517 None 0.801 N 0.465 0.356 0.664688822591 gnomAD-4.0.0 6.87451E-07 None None None None I None 0 0 None 0 0 None 0 0 9.02032E-07 0 0
I/V 18382 Ig-115 1 rs1233345100 0.0895 -0.59 0.005 N 0.188 0.064 0.346544149963 gnomAD-2.1.1 8.24E-06 None None None None I None 0 0 None 0 5.68E-05 None 0 None 0 9.05E-06 0
I/V 18382 Ig-115 1 rs1233345100 0.0895 -0.59 0.005 N 0.188 0.064 0.346544149963 gnomAD-4.0.0 3.43698E-06 None None None None I None 0 0 None 0 5.0674E-05 None 0 0 9.02017E-07 1.17805E-05 1.66456E-05
I/V 18688 Ig-116 1 None 0.0961 None 0.993 N 0.218 0.291 0.417716871343 gnomAD-4.0.0 2.09355E-06 None None None None N None 0 0 None 0 0 None 0 0 2.72843E-06 0 0
D/E 19095 Ig-117 1 None 0.9737 None 1.0 N 0.501 0.315 0.431035450679 gnomAD-4.0.0 6.84479E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9964E-07 0 0
D/V 19095 Ig-117 1 None 0.9922 None 1.0 N 0.763 0.615 0.713510005162 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/N 19391 Ig-118 1 rs377633051 0.2094 -0.117 0.447 N 0.239 0.219 None gnomAD-2.1.1 4.66E-05 None None None None I None 4.54884E-04 5.69E-05 None 0 0 None 0 None 0 0 0
D/N 19391 Ig-118 1 rs377633051 0.2094 -0.117 0.447 N 0.239 0.219 None gnomAD-3.1.2 9.21E-05 None None None None I None 3.37985E-04 0 0 0 0 None 0 0 0 0 0
D/N 19391 Ig-118 1 rs377633051 0.2094 -0.117 0.447 N 0.239 0.219 None gnomAD-4.0.0 1.55E-05 None None None None I None 2.40481E-04 3.34079E-05 None 3.37906E-05 0 None 0 0 3.39105E-06 0 0
D/Y 19391 Ig-118 1 None 0.4921 None 0.996 N 0.578 0.381 0.726185039024 gnomAD-4.0.0 6.84507E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99614E-07 0 0
A/D 19790 Ig-119 1 None 0.8032 None 1.0 N 0.707 0.436 0.669824099912 gnomAD-4.0.0 6.8448E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9968E-07 0 0
A/V 19790 Ig-119 1 rs1410710532 0.3556 -0.576 0.984 N 0.572 0.382 0.539879176108 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
A/V 19790 Ig-119 1 rs1410710532 0.3556 -0.576 0.984 N 0.572 0.382 0.539879176108 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
A/V 19790 Ig-119 1 rs1410710532 0.3556 -0.576 0.984 N 0.572 0.382 0.539879176108 gnomAD-4.0.0 1.8599E-06 None None None None N None 0 0 None 0 0 None 0 0 8.4782E-07 2.19679E-05 0
L/V 20080 Ig-120 1 rs1559592788 0.1658 None 0.003 N 0.211 0.111 0.209622950755 gnomAD-2.1.1 4.44E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.42E-06 0
L/V 20080 Ig-120 1 rs1559592788 0.1658 None 0.003 N 0.211 0.111 0.209622950755 gnomAD-4.0.0 2.78783E-06 None None None None N None 0 0 None 0 0 None 0 0 2.71797E-06 1.23907E-05 0
D/N 20479 Ig-121 1 rs773754692 0.7201 0.342 0.999 N 0.685 0.403 0.188950314367 gnomAD-2.1.1 4.69E-06 None None None None N None 0 0 None 0 5.79E-05 None 0 None 0 0 0
D/N 20479 Ig-121 1 rs773754692 0.7201 0.342 0.999 N 0.685 0.403 0.188950314367 gnomAD-4.0.0 1.7074E-06 None None None None N None 0 0 None 0 2.803E-05 None 0 0 0 0 0
P/L 20769 Ig-122 1 rs772498581 0.9914 None 1.0 D 0.796 0.623 0.872428163933 gnomAD-4.0.0 6.84347E-07 None None None None N None 2.989E-05 0 None 0 0 None 0 0 0 0 0
P/Q 20769 Ig-122 1 None 0.9992 -1.364 1.0 D 0.792 0.648 0.725290542326 gnomAD-2.1.1 1.07E-05 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 7.83E-06 0
P/Q 20769 Ig-122 1 None 0.9992 -1.364 1.0 D 0.792 0.648 0.725290542326 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/Q 20769 Ig-122 1 None 0.9992 -1.364 1.0 D 0.792 0.648 0.725290542326 gnomAD-4.0.0 1.85963E-06 None None None None N None 2.67158E-05 0 None 0 0 None 0 0 8.47722E-07 0 0
P/T 20769 Ig-122 1 None 0.9951 None 1.0 D 0.775 0.612 0.704159939526 gnomAD-4.0.0 7.20193E-06 None None None None N None 0 0 None 0 0 None 0 0 7.87501E-06 0 0
D/E 21177 Ig-123 1 rs879247635 0.8259 None 0.993 N 0.503 0.324 0.402326594622 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
D/E 21177 Ig-123 1 rs879247635 0.8259 None 0.993 N 0.503 0.324 0.402326594622 gnomAD-4.0.0 6.57661E-06 None None None None N None 2.41243E-05 0 None 0 0 None 0 0 0 0 0
S/I 21866 Ig-125 1 None 0.5517 None 0.939 N 0.41 0.327 0.73638873623 gnomAD-4.0.0 6.87581E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.66423E-05
S/N 21866 Ig-125 1 rs2048167359 0.1504 None 0.521 N 0.286 0.108 0.222439326576 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/N 21866 Ig-125 1 rs2048167359 0.1504 None 0.521 N 0.286 0.108 0.222439326576 gnomAD-4.0.0 3.73501E-06 None None None None N None 0 0 None 0 0 None 0 0 5.10437E-06 0 0
A/E 22265 Ig-126 1 rs750836266 0.5792 -0.341 1.0 N 0.614 0.468 0.487912462561 gnomAD-2.1.1 4.1E-06 None None None None I None 0 0 None 0 5.68E-05 None 0 None 0 0 0
A/E 22265 Ig-126 1 rs750836266 0.5792 -0.341 1.0 N 0.614 0.468 0.487912462561 gnomAD-4.0.0 2.05737E-06 None None None None I None 0 0 None 0 2.53447E-05 None 0 0 1.80066E-06 0 0
A/V 22265 Ig-126 1 rs750836266 0.1947 -0.036 1.0 D 0.599 0.378 0.423119698836 gnomAD-2.1.1 1.76336E-04 None None None None I None 0 0 None 0 0 None 1.38955E-03 None 0 1.81E-05 0
A/V 22265 Ig-126 1 rs750836266 0.1947 -0.036 1.0 D 0.599 0.378 0.423119698836 gnomAD-3.1.2 3.29E-05 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 8.28844E-04 0
A/V 22265 Ig-126 1 rs750836266 0.1947 -0.036 1.0 D 0.599 0.378 0.423119698836 gnomAD-4.0.0 8.07281E-05 None None None None I None 1.33547E-05 1.68073E-05 None 0 0 None 0 1.65563E-04 9.33252E-06 1.25533E-03 4.8151E-05
P/T 22950 Ig-128 1 rs770007899 0.1308 -0.921 0.491 N 0.377 0.226 0.307966526162 gnomAD-2.1.1 2.1E-05 None None None None N None 0 0 None 0 2.82358E-04 None 0 None 0 0 0
P/T 22950 Ig-128 1 rs770007899 0.1308 -0.921 0.491 N 0.377 0.226 0.307966526162 gnomAD-4.0.0 4.17234E-06 None None None None N None 0 0 None 0 1.53178E-04 None 0 0 0 0 0
G/D 23637 Ig-130 1 rs772116474 0.3304 None 0.014 N 0.258 0.268 0.1749357433 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
G/S 23637 Ig-130 1 rs1243986262 0.1367 -0.398 0.153 N 0.191 0.143 0.152612264143 gnomAD-2.1.1 4.05E-06 None None None None I None 0 2.91E-05 None 0 0 None 0 None 0 0 0
G/S 23637 Ig-130 1 rs1243986262 0.1367 -0.398 0.153 N 0.191 0.143 0.152612264143 gnomAD-4.0.0 1.36925E-06 None None None None I None 0 2.24054E-05 None 0 0 None 0 0 8.99722E-07 0 0
D/N 24431 Ig-132 1 rs757317072 0.5803 0.264 0.999 N 0.639 0.43 0.408036853922 gnomAD-2.1.1 3.63E-05 None None None None I None 0 0 None 0 5.04145E-04 None 0 None 0 0 0
D/N 24431 Ig-132 1 rs757317072 0.5803 0.264 0.999 N 0.639 0.43 0.408036853922 gnomAD-4.0.0 9.55219E-06 None None None None I None 0 0 None 0 1.11198E-04 None 0 0 5.71899E-06 0 0
D/V 24431 Ig-132 1 rs754343858 0.8694 0.309 1.0 D 0.671 0.4 0.78964934489 gnomAD-2.1.1 1.07E-05 None None None None I None 0 2.83E-05 None 0 0 None 0 None 0 7.84E-06 1.40726E-04
D/V 24431 Ig-132 1 rs754343858 0.8694 0.309 1.0 D 0.671 0.4 0.78964934489 gnomAD-3.1.2 3.95E-05 None None None None I None 2.41E-05 2.62123E-04 0 0 0 None 0 0 1.47E-05 0 0
D/V 24431 Ig-132 1 rs754343858 0.8694 0.309 1.0 D 0.671 0.4 0.78964934489 gnomAD-4.0.0 1.15356E-05 None None None None I None 1.69188E-05 8.47745E-05 None 0 0 None 0 0 4.78829E-06 0 2.84511E-05
I/T 25111 Ig-134 1 rs879132850 0.8987 None 0.892 N 0.616 0.607 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 25111 Ig-134 1 rs879132850 0.8987 None 0.892 N 0.616 0.607 None gnomAD-4.0.0 2.56315E-06 None None None None I None 0 0 None 0 0 None 0 0 4.78806E-06 0 0
L/P 25514 Ig-135 1 rs1553601755 0.1543 None 0.003 N 0.381 0.212 0.604659335069 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/P 25514 Ig-135 1 rs1553601755 0.1543 None 0.003 N 0.381 0.212 0.604659335069 gnomAD-4.0.0 6.57687E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4708E-05 0 0
L/V 25514 Ig-135 1 None 0.0837 None 0.001 N 0.203 0.038 0.141422826196 gnomAD-4.0.0 1.59377E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86134E-06 0 0
P/T 25798 Ig-136 1 rs1246528312 0.943 -1.691 0.999 D 0.734 0.584 0.653491938199 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.67168E-04
P/T 25798 Ig-136 1 rs1246528312 0.943 -1.691 0.999 D 0.734 0.584 0.653491938199 gnomAD-4.0.0 1.59289E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02608E-05
I/L 26193 Ig-137 1 rs727505241 0.2199 -0.165 0.003 N 0.12 0.168 0.405150804464 gnomAD-2.1.1 8.16E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.8E-05 0
I/L 26193 Ig-137 1 rs727505241 0.2199 -0.165 0.003 N 0.12 0.168 0.405150804464 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/L 26193 Ig-137 1 rs727505241 0.2199 -0.165 0.003 N 0.12 0.168 0.405150804464 gnomAD-4.0.0 9.94007E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3586E-05 0 0
L/I 26594 Ig-138 1 rs759737599 0.0861 -0.004 0.067 N 0.212 0.112 0.269558022972 gnomAD-2.1.1 5.63E-05 None None None None N None 0 3.76702E-04 None 0 0 None 0 None 0 0 1.65618E-04
L/I 26594 Ig-138 1 rs759737599 0.0861 -0.004 0.067 N 0.212 0.112 0.269558022972 gnomAD-4.0.0 2.06916E-05 None None None None N None 0 2.97265E-04 None 0 0 None 0 0 0 0 0
P/S 26880 Ig-139 1 None 0.9713 None 1.0 D 0.767 0.805 0.662503200617 gnomAD-4.0.0 1.59212E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85964E-06 0 0
E/K 27676 Ig-141 1 rs1424922146 0.6744 None 0.958 N 0.563 0.439 0.374434639691 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
E/K 27676 Ig-141 1 rs1424922146 0.6744 None 0.958 N 0.563 0.439 0.374434639691 gnomAD-4.0.0 6.57307E-06 None None None None N None 0 6.5548E-05 None 0 0 None 0 0 0 0 0
E/Q 27676 Ig-141 1 rs1424922146 0.3872 None 0.994 N 0.643 0.247 0.416833835346 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
E/V 27676 Ig-141 1 rs1282696852 0.3836 None 0.994 N 0.745 0.575 0.469165163779 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
E/V 27676 Ig-141 1 rs1282696852 0.3836 None 0.994 N 0.745 0.575 0.469165163779 gnomAD-4.0.0 6.57523E-06 None None None None N None 0 6.55652E-05 None 0 0 None 0 0 0 0 0
P/A 27963 Ig-142 1 None 0.6488 None 1.0 D 0.708 0.589 0.699206367509 gnomAD-4.0.0 1.59311E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86007E-06 0 0
M/I 28358 Ig-143 1 rs973736756 0.4603 None None N 0.069 0.122 0.432493127443 gnomAD-4.0.0 1.36835E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79889E-06 0 0
M/K 28358 Ig-143 1 None 0.2714 0.896 None N 0.137 0.332 0.542675667512 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.56E-05 None 0 None 0 0 0
M/L 28358 Ig-143 1 rs368069666 0.1485 0.425 0.01 N 0.2 0.137 0.591025817267 gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.91E-05 0
M/L 28358 Ig-143 1 rs368069666 0.1485 0.425 0.01 N 0.2 0.137 0.591025817267 gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 0 0 None 0 0 4.41E-05 0 0
M/L 28358 Ig-143 1 rs368069666 0.1485 0.425 0.01 N 0.2 0.137 0.591025817267 gnomAD-4.0.0 2.85046E-05 None None None None I None 0 0 None 0 0 None 0 0 3.81413E-05 0 1.60102E-05
M/R 28358 Ig-143 1 rs766947305 0.2864 None 0.112 N 0.313 0.263 0.548571244948 gnomAD-4.0.0 1.36836E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.31868E-05 0
M/T 28358 Ig-143 1 rs766947305 0.2994 0.655 0.001 N 0.134 0.261 0.67367363106 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
M/T 28358 Ig-143 1 rs766947305 0.2994 0.655 0.001 N 0.134 0.261 0.67367363106 gnomAD-4.0.0 2.05254E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69835E-06 0 0
D/A 28755 Ig-144 1 rs1702996133 0.1976 None 0.379 N 0.41 0.225 0.371531589858 gnomAD-4.0.0 1.36965E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79899E-06 0 0
D/V 28755 Ig-144 1 None 0.1646 None 0.379 N 0.448 0.29 0.496165130923 gnomAD-4.0.0 4.10895E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39696E-06 0 0
D/A 29045 Ig-145 1 rs1364010226 0.2618 0.108 0.989 N 0.421 0.296 0.401327265625 gnomAD-2.1.1 3.18E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
D/A 29045 Ig-145 1 rs1364010226 0.2618 0.108 0.989 N 0.421 0.296 0.401327265625 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/A 29045 Ig-145 1 rs1364010226 0.2618 0.108 0.989 N 0.421 0.296 0.401327265625 gnomAD-4.0.0 6.56892E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46977E-05 0 0
D/G 29045 Ig-145 1 rs1364010226 0.4529 -0.217 0.978 N 0.469 0.264 0.325263233342 gnomAD-2.1.1 4.16E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.1E-06 0
D/G 29045 Ig-145 1 rs1364010226 0.4529 -0.217 0.978 N 0.469 0.264 0.325263233342 gnomAD-4.0.0 1.60851E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86942E-06 0 0
D/H 29045 Ig-145 1 rs775369442 0.3684 0.131 0.997 N 0.477 0.296 0.366848117066 gnomAD-2.1.1 8.33E-06 None None None None I None 0 0 None 0 0 None 7.16E-05 None 0 0 0
D/H 29045 Ig-145 1 rs775369442 0.3684 0.131 0.997 N 0.477 0.296 0.366848117066 gnomAD-4.0.0 4.82995E-06 None None None None I None 0 0 None 0 0 None 0 0 0 4.46681E-05 0
I/K 30927 Ig-150 1 rs531432790 0.7402 -0.978 0.999 N 0.635 0.564 0.836495694078 gnomAD-2.1.1 6.31765E-04 None None None None N None 0 2.9E-05 None 0 0 None 4.73825E-03 None 0 7.1E-05 4.96853E-04
I/K 30927 Ig-150 1 rs531432790 0.7402 -0.978 0.999 N 0.635 0.564 0.836495694078 gnomAD-3.1.2 1.97166E-04 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 6.00663E-03 0
I/K 30927 Ig-150 1 rs531432790 0.7402 -0.978 0.999 N 0.635 0.564 0.836495694078 1000 genomes 7.98722E-04 None None None None N None 0 0 None None 0 0 None None None 4.1E-03 None
I/K 30927 Ig-150 1 rs531432790 0.7402 -0.978 0.999 N 0.635 0.564 0.836495694078 gnomAD-4.0.0 3.22298E-04 None None None None N None 1.3328E-05 4.99917E-05 None 0 0 None 0 0 2.88181E-05 5.05039E-03 3.52113E-04
I/L 30927 Ig-150 1 rs1416836304 0.1323 None 0.104 N 0.209 0.16 0.188950314367 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/L 30927 Ig-150 1 rs1416836304 0.1323 None 0.104 N 0.209 0.16 0.188950314367 gnomAD-4.0.0 6.57091E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46977E-05 0 0
I/M 30927 Ig-150 1 None 0.1214 None 0.997 N 0.451 0.306 0.202086224978 gnomAD-4.0.0 4.77716E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71615E-06 0 3.02425E-05
I/T 30927 Ig-150 1 None 0.1972 None 0.998 N 0.457 0.476 0.674404827817 gnomAD-4.0.0 6.15957E-06 None None None None N None 5.9755E-05 0 None 0 0 None 0 0 1.79889E-06 5.79656E-05 0
I/V 30927 Ig-150 1 rs1416836304 0.1053 -1.067 0.889 N 0.279 0.176 0.395143324098 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 1.11532E-04 None 0 None 0 0 0
I/V 30927 Ig-150 1 rs1416836304 0.1053 -1.067 0.889 N 0.279 0.176 0.395143324098 gnomAD-4.0.0 3.18457E-06 None None None None N None 0 0 None 0 5.54877E-05 None 0 0 0 0 0
T/A 31218 Ig-151 1 None 0.0702 None 0.041 N 0.189 0.225 0.139678290688 gnomAD-4.0.0 1.5917E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43291E-05 0
A/V 32017 Ig-153 1 rs1192866113 0.2515 -0.264 0.22 N 0.351 0.213 0.446111551642 gnomAD-2.1.1 6.37E-05 None None None None N None 0 0 None 0 0 None 0 None 5.75374E-04 0 0
A/V 32017 Ig-153 1 rs1192866113 0.2515 -0.264 0.22 N 0.351 0.213 0.446111551642 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 1.88395E-04 0 0 0 0
A/V 32017 Ig-153 1 rs1192866113 0.2515 -0.264 0.22 N 0.351 0.213 0.446111551642 gnomAD-4.0.0 1.31489E-05 None None None None N None 0 0 None 0 0 None 1.88395E-04 0 0 0 0
D/A 32307 Ig-154 1 None 0.4096 None 0.201 D 0.581 0.279 0.451786746415 gnomAD-4.0.0 2.06866E-06 None None None None I None 0 0 None 0 7.60456E-05 None 0 0 0 0 0
D/G 32307 Ig-154 1 rs942897847 0.6272 -0.007 0.334 D 0.625 0.268 0.287603790349 gnomAD-2.1.1 1.82E-05 None None None None I None 2.07452E-04 0 None 0 0 None 0 None 0 0 0
D/G 32307 Ig-154 1 rs942897847 0.6272 -0.007 0.334 D 0.625 0.268 0.287603790349 gnomAD-3.1.2 3.29E-05 None None None None I None 1.20604E-04 0 0 0 0 None 0 0 0 0 0
D/G 32307 Ig-154 1 rs942897847 0.6272 -0.007 0.334 D 0.625 0.268 0.287603790349 gnomAD-4.0.0 6.24064E-06 None None None None I None 1.20556E-04 0 None 0 0 None 0 0 0 0 1.61415E-05
D/N 32307 Ig-154 1 rs1474585549 0.1594 0.345 0.081 D 0.326 0.242 0.27855597813 gnomAD-2.1.1 1.24E-05 None None None None I None 0 0 None 0 0 None 3.48E-05 None 0 1.82E-05 0
D/N 32307 Ig-154 1 rs1474585549 0.1594 0.345 0.081 D 0.326 0.242 0.27855597813 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/N 32307 Ig-154 1 rs1474585549 0.1594 0.345 0.081 D 0.326 0.242 0.27855597813 gnomAD-4.0.0 1.12479E-05 None None None None I None 0 1.69394E-05 None 0 2.24185E-05 None 0 0 5.97895E-06 7.81424E-05 3.23394E-05
E/K 32708 Ig-155 1 rs1428233034 0.1035 0.255 0.064 N 0.171 0.227 0.268211541103 gnomAD-2.1.1 1.61E-05 None None None None N None 0 8.7E-05 None 0 0 None 0 None 0 0 1.66168E-04
E/K 32708 Ig-155 1 rs1428233034 0.1035 0.255 0.064 N 0.171 0.227 0.268211541103 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
E/K 32708 Ig-155 1 rs1428233034 0.1035 0.255 0.064 N 0.171 0.227 0.268211541103 gnomAD-4.0.0 4.33876E-06 None None None None N None 0 1.00043E-04 None 0 0 None 0 0 8.47745E-07 0 0
P/L 33101 Ig-156 1 None 0.9265 None 1.0 D 0.813 0.651 0.916515394442 gnomAD-4.0.0 1.60306E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.44238E-05 0
P/T 33496 Ig-158 1 rs1691443829 0.9758 None 1.0 D 0.898 0.724 0.763848737128 gnomAD-4.0.0 1.59184E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85881E-06 0 0
P/L 33596 Ig-159 1 None 0.8676 None 0.997 D 0.787 0.686 0.88102178314 gnomAD-4.0.0 6.95303E-07 None None None None N None 0 2.40073E-05 None 0 0 None 0 0 0 0 0
P/L 34137 Ig-160 1 None 0.5562 None 0.104 N 0.404 0.236 0.516827169674 gnomAD-4.0.0 1.59096E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/S 34258 Ig-161 1 rs752360286 0.9676 -2.446 0.885 D 0.785 0.454 0.31411915649 gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
P/S 34258 Ig-161 1 rs752360286 0.9676 -2.446 0.885 D 0.785 0.454 0.31411915649 gnomAD-4.0.0 1.02624E-05 None None None None N None 0 0 None 0 0 None 0 0 1.34911E-05 0 0
P/T 34258 Ig-161 1 rs752360286 0.9509 -1.899 0.982 N 0.79 0.454 0.346315397577 gnomAD-2.1.1 4.42E-05 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 8.85E-05 0
P/T 34258 Ig-161 1 rs752360286 0.9509 -1.899 0.982 N 0.79 0.454 0.346315397577 gnomAD-3.1.2 4.6E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 7.35E-05 0 0
P/T 34258 Ig-161 1 rs752360286 0.9509 -1.899 0.982 N 0.79 0.454 0.346315397577 gnomAD-4.0.0 3.90374E-05 None None None None N None 2.66987E-05 6.66644E-05 None 0 0 None 0 1.64366E-04 4.32251E-05 1.09779E-05 6.40369E-05
P/L 34363 Ig-162 1 rs1457631231 0.9924 None 0.235 D 0.743 0.732 0.856139998468 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 34363 Ig-162 1 rs1457631231 0.9924 None 0.235 D 0.743 0.732 0.856139998468 gnomAD-4.0.0 6.57333E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47007E-05 0 0
P/R 34363 Ig-162 1 rs1457631231 0.9984 -0.798 0.997 D 0.875 0.778 0.893338283714 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/R 34363 Ig-162 1 rs1457631231 0.9984 -0.798 0.997 D 0.875 0.778 0.893338283714 gnomAD-4.0.0 1.59134E-06 None None None None N None 0 2.28666E-05 None 0 0 None 0 0 0 0 0
P/S 34363 Ig-162 1 rs771573240 0.9956 -2.062 0.997 D 0.883 0.749 0.725343530507 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
P/S 34363 Ig-162 1 rs771573240 0.9956 -2.062 0.997 D 0.883 0.749 0.725343530507 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 34363 Ig-162 1 rs771573240 0.9956 -2.062 0.997 D 0.883 0.749 0.725343530507 gnomAD-4.0.0 4.95735E-06 None None None None N None 0 0 None 0 0 None 0 0 6.78056E-06 0 0
P/T 34363 Ig-162 1 None 0.9943 None 0.997 D 0.875 0.749 0.858169626448 gnomAD-4.0.0 6.84178E-07 None None None None N None 2.98739E-05 0 None 0 0 None 0 0 0 0 0
P/T 34942 Ig-163 1 None 0.9882 None 1.0 D 0.908 0.801 0.707650254962 gnomAD-4.0.0 1.59089E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
A/G 35129 Ig-164 1 rs1688988300 0.4653 None 0.998 N 0.64 0.354 0.528712057427 gnomAD-4.0.0 2.73655E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59759E-06 0 0
P/R 35420 Ig-166 1 rs367732354 0.9433 -0.896 0.44 D 0.726 0.735 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/R 35420 Ig-166 1 rs367732354 0.9433 -0.896 0.44 D 0.726 0.735 None gnomAD-4.0.0 6.57402E-06 None None None None N None 2.41488E-05 0 None 0 0 None 0 0 0 0 0
P/S 35420 Ig-166 1 rs567191587 0.8034 -2.182 0.611 D 0.651 0.651 0.518147779662 gnomAD-2.1.1 3.21E-05 None None None None N None 0 0 None 0 4.60782E-04 None 0 None 0 0 0
P/S 35420 Ig-166 1 rs567191587 0.8034 -2.182 0.611 D 0.651 0.651 0.518147779662 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 5.78258E-04 None 0 0 0 0 0
P/S 35420 Ig-166 1 rs567191587 0.8034 -2.182 0.611 D 0.651 0.651 0.518147779662 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
P/S 35420 Ig-166 1 rs567191587 0.8034 -2.182 0.611 D 0.651 0.651 0.518147779662 gnomAD-4.0.0 4.95683E-06 None None None None N None 0 0 None 0 1.78301E-04 None 0 0 0 0 0
A/D 35607 Ig-167 1 None 0.4015 None 0.322 N 0.305 0.205 0.346315397577 gnomAD-4.0.0 6.8414E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99395E-07 0 0
A/V 35607 Ig-167 1 rs377337528 0.1801 -0.06 0.001 N 0.138 0.085 None gnomAD-2.1.1 1.21232E-04 None None None None I None 1.65289E-04 2.83E-05 None 0 0 None 0 None 0 2.26117E-04 0
A/V 35607 Ig-167 1 rs377337528 0.1801 -0.06 0.001 N 0.138 0.085 None gnomAD-3.1.2 9.2E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 1.61712E-04 0 0
A/V 35607 Ig-167 1 rs377337528 0.1801 -0.06 0.001 N 0.138 0.085 None gnomAD-4.0.0 1.69162E-04 None None None None I None 8.01068E-05 1.66656E-05 None 0 0 None 0 0 2.22056E-04 0 6.40389E-05
P/A 35702 Ig-168 1 rs551126367 0.6028 -1.204 1.0 D 0.821 0.878 0.651230687639 gnomAD-2.1.1 7.19E-06 None None None None N None 8.33E-05 0 None 0 0 None 0 None 0 0 0
P/A 35702 Ig-168 1 rs551126367 0.6028 -1.204 1.0 D 0.821 0.878 0.651230687639 gnomAD-3.1.2 2.63E-05 None None None None N None 9.65E-05 0 0 0 0 None 0 0 0 0 0
P/A 35702 Ig-168 1 rs551126367 0.6028 -1.204 1.0 D 0.821 0.878 0.651230687639 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
P/A 35702 Ig-168 1 rs551126367 0.6028 -1.204 1.0 D 0.821 0.878 0.651230687639 gnomAD-4.0.0 2.62643E-05 None None None None N None 9.62418E-05 0 None 0 0 None 0 0 0 0 0
P/L 35702 Ig-168 1 rs772957495 0.8433 -0.382 1.0 D 0.869 0.86 None gnomAD-2.1.1 1.43818E-04 None None None None N None 4.16E-05 0 None 0 0 None 0 None 0 2.98925E-04 1.41323E-04
P/L 35702 Ig-168 1 rs772957495 0.8433 -0.382 1.0 D 0.869 0.86 None gnomAD-3.1.2 6.57E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47003E-04 0 0
P/L 35702 Ig-168 1 rs772957495 0.8433 -0.382 1.0 D 0.869 0.86 None gnomAD-4.0.0 2.03995E-04 None None None None N None 1.33515E-05 0 None 0 0 None 0 0 2.75572E-04 0 4.80523E-05
P/T 35702 Ig-168 1 rs551126367 0.8808 -1.529 1.0 D 0.875 0.905 0.814869350715 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 3.29E-05 None 0 0 0
P/T 35702 Ig-168 1 rs551126367 0.8808 -1.529 1.0 D 0.875 0.905 0.814869350715 gnomAD-4.0.0 2.05388E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.48473E-05 0
P/L 35897 Ig-169 1 rs1558956138 0.9381 None 1.0 D 0.901 0.698 0.745084277401 gnomAD-4.0.0 1.64727E-06 None None None -0.723(OBSL1) -1.155(OBSCN) N None 6.0154E-05 0 None 0 0 None 0 0 0 0 0
P/S 35897 Ig-169 1 rs1270719592 0.948 None 1.0 D 0.905 0.718 0.721568202884 gnomAD-4.0.0 3.29856E-06 None None None -0.94(OBSL1) -1.055(OBSCN) N None 0 0 None 0 5.59409E-05 None 0 0 0 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.