SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G/S | 53 | Ig-1 | 48 | rs150902810 | 0.1122 | -1.021 | 1.0 | N | 0.729 | 0.392 | None | gnomAD-2.1.1 | 3.18E-05 | None | None | None | 0.231(TCAP) | N | None | 6.15E-05 | 5.78E-05 | None | 0 | 5.45E-05 | None | 0 | None | 0 | 3.52E-05 | 0 |
G/S | 53 | Ig-1 | 48 | rs150902810 | 0.1122 | -1.021 | 1.0 | N | 0.729 | 0.392 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | 0.231(TCAP) | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
G/S | 53 | Ig-1 | 48 | rs150902810 | 0.1122 | -1.021 | 1.0 | N | 0.729 | 0.392 | None | 1000 genomes | 1.99681E-04 | None | None | None | 0.231(TCAP) | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
G/S | 53 | Ig-1 | 48 | rs150902810 | 0.1122 | -1.021 | 1.0 | N | 0.729 | 0.392 | None | gnomAD-4.0.0 | 7.43445E-06 | None | None | None | 0.231(TCAP) | N | None | 1.3328E-05 | 3.33222E-05 | None | 0 | 0 | None | 0 | 0 | 2.54236E-06 | 3.29395E-05 | 4.79969E-05 |
G/V | 53 | Ig-1 | 48 | None | 0.4069 | None | 1.0 | N | 0.804 | 0.486 | 0.443999229985 | gnomAD-4.0.0 | 3.42034E-06 | None | None | None | -0.001(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59717E-06 | 0 | 1.65579E-05 |
D/N | 149 | Ig-2 | 46 | rs1465558432 | 0.5779 | -0.606 | 0.999 | N | 0.655 | 0.356 | 0.289098819767 | gnomAD-2.1.1 | 1.19E-05 | None | None | None | -1.562(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.64E-05 | 0 |
D/N | 149 | Ig-2 | 46 | rs1465558432 | 0.5779 | -0.606 | 0.999 | N | 0.655 | 0.356 | 0.289098819767 | gnomAD-4.0.0 | 5.47248E-06 | None | None | None | -1.562(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19436E-06 | 0 | 0 |
D/N | 988 | Ig-3 | 46 | None | 0.8775 | None | 1.0 | N | 0.641 | 0.349 | 0.324161360171 | gnomAD-4.0.0 | 1.36815E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7986E-06 | 0 | 0 |
R/G | 1127 | Ig-4 | 46 | None | 0.9816 | None | 1.0 | N | 0.716 | 0.601 | 0.53837629882 | gnomAD-4.0.0 | 5.47276E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19463E-06 | 0 | 0 |
R/S | 1336 | Ig-5 | 46 | rs1449428038 | 0.8549 | -0.685 | 0.896 | N | 0.465 | 0.34 | 0.250579442822 | gnomAD-2.1.1 | 4E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
R/S | 1336 | Ig-5 | 46 | rs1449428038 | 0.8549 | -0.685 | 0.896 | N | 0.465 | 0.34 | 0.250579442822 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
T/I | 1502 | Ig-6 | 46 | None | 0.4494 | None | 0.999 | N | 0.702 | 0.582 | 0.534093007224 | gnomAD-4.0.0 | 1.36835E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79873E-06 | 0 | 0 |
T/N | 1502 | Ig-6 | 46 | rs2092362672 | 0.1952 | None | 0.999 | N | 0.689 | 0.391 | 0.463243292966 | gnomAD-4.0.0 | 1.36835E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79873E-06 | 0 | 0 |
K/N | 1603 | Ig-7 | 48 | rs764249850 | 0.2026 | -0.496 | None | N | 0.095 | 0.099 | 0.166414681773 | gnomAD-2.1.1 | 7.96E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.08873E-04 | None | 0 | None | 0 | 0 | 0 |
K/N | 1603 | Ig-7 | 48 | rs764249850 | 0.2026 | -0.496 | None | N | 0.095 | 0.099 | 0.166414681773 | gnomAD-4.0.0 | 1.5907E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77346E-05 | None | 0 | 0 | 0 | 0 | 0 |
K/Q | 1603 | Ig-7 | 48 | rs754087999 | 0.0977 | -0.399 | 0.055 | N | 0.211 | 0.194 | 0.251116650651 | gnomAD-2.1.1 | 2.39E-05 | None | None | None | None | N | None | 0 | 1.15647E-04 | None | 0 | 0 | None | 0 | None | 0 | 1.76E-05 | 0 |
K/Q | 1603 | Ig-7 | 48 | rs754087999 | 0.0977 | -0.399 | 0.055 | N | 0.211 | 0.194 | 0.251116650651 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
K/Q | 1603 | Ig-7 | 48 | rs754087999 | 0.0977 | -0.399 | 0.055 | N | 0.211 | 0.194 | 0.251116650651 | gnomAD-4.0.0 | 1.67287E-05 | None | None | None | None | N | None | 0 | 4.99967E-05 | None | 0 | 0 | None | 0 | 0 | 1.94916E-05 | 1.09784E-05 | 0 |
K/T | 1603 | Ig-7 | 48 | None | 0.155 | None | 0.055 | N | 0.327 | 0.251 | 0.280181792013 | gnomAD-4.0.0 | 1.59069E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85678E-06 | 0 | 0 |
R/S | 1750 | Ig-8 | 48 | rs924534786 | 0.9804 | None | 1.0 | D | 0.751 | 0.526 | 0.604474940213 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 1750 | Ig-8 | 48 | rs924534786 | 0.9804 | None | 1.0 | D | 0.751 | 0.526 | 0.604474940213 | gnomAD-4.0.0 | 6.5703E-06 | None | None | None | None | I | None | 2.41243E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 2123 | Ig-10 | 46 | rs530807674 | 0.6478 | -0.264 | 1.0 | D | 0.689 | 0.768 | 0.704837425536 | gnomAD-2.1.1 | 1.42E-05 | None | None | None | None | N | None | 4.01E-05 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 0 | 1.38812E-04 |
R/L | 2123 | Ig-10 | 46 | rs530807674 | 0.6478 | -0.264 | 1.0 | D | 0.689 | 0.768 | 0.704837425536 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 6.22148E-04 | 0 |
R/L | 2123 | Ig-10 | 46 | rs530807674 | 0.6478 | -0.264 | 1.0 | D | 0.689 | 0.768 | 0.704837425536 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
R/L | 2123 | Ig-10 | 46 | rs530807674 | 0.6478 | -0.264 | 1.0 | D | 0.689 | 0.768 | 0.704837425536 | gnomAD-4.0.0 | 8.67428E-06 | None | None | None | None | N | None | 1.33298E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.31764E-04 | 1.59985E-05 |
R/Q | 2123 | Ig-10 | 46 | rs530807674 | 0.187 | -0.626 | 1.0 | D | 0.693 | 0.611 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.84593E-04 | 0 | None | 0 | 0 | None | 9.8E-05 | None | 0 | 1.76E-05 | 0 |
R/Q | 2123 | Ig-10 | 46 | rs530807674 | 0.187 | -0.626 | 1.0 | D | 0.693 | 0.611 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 1.93125E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 2123 | Ig-10 | 46 | rs530807674 | 0.187 | -0.626 | 1.0 | D | 0.693 | 0.611 | None | gnomAD-4.0.0 | 2.2307E-05 | None | None | None | None | N | None | 2.80381E-04 | 0 | None | 0 | 6.69225E-05 | None | 0 | 0 | 8.47462E-06 | 2.19597E-05 | 0 |
R/W | 2123 | Ig-10 | 46 | rs777316854 | 0.6434 | -0.586 | 1.0 | D | 0.7 | 0.756 | 0.663099739152 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 6.15E-05 | 2.9E-05 | None | 0 | 5.46E-05 | None | 3.27E-05 | None | 0 | 3.52E-05 | 0 |
R/W | 2123 | Ig-10 | 46 | rs777316854 | 0.6434 | -0.586 | 1.0 | D | 0.7 | 0.756 | 0.663099739152 | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 9.66E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/W | 2123 | Ig-10 | 46 | rs777316854 | 0.6434 | -0.586 | 1.0 | D | 0.7 | 0.756 | 0.663099739152 | gnomAD-4.0.0 | 1.17732E-05 | None | None | None | None | N | None | 6.67735E-05 | 1.66778E-05 | None | 0 | 2.23035E-05 | None | 0 | 0 | 7.62711E-06 | 2.19602E-05 | 1.60046E-05 |
K/Q | 2219 | Ig-11 | 46 | rs1292302676 | 0.459 | -0.618 | 1.0 | D | 0.712 | 0.453 | 0.371718192555 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
K/Q | 2219 | Ig-11 | 46 | rs1292302676 | 0.459 | -0.618 | 1.0 | D | 0.712 | 0.453 | 0.371718192555 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/Q | 2219 | Ig-11 | 46 | rs1292302676 | 0.459 | -0.618 | 1.0 | D | 0.712 | 0.453 | 0.371718192555 | gnomAD-4.0.0 | 3.84199E-06 | None | None | None | None | N | None | 3.38192E-05 | 1.69463E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/R | 2219 | Ig-11 | 46 | rs1482793298 | 0.1443 | -0.407 | 0.999 | N | 0.54 | 0.341 | 0.340510301474 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
K/R | 2219 | Ig-11 | 46 | rs1482793298 | 0.1443 | -0.407 | 0.999 | N | 0.54 | 0.341 | 0.340510301474 | gnomAD-4.0.0 | 1.59078E-06 | None | None | None | None | N | None | 0 | 2.28655E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/N | 2311 | Ig-12 | 45 | None | 0.8041 | None | 1.0 | N | 0.699 | 0.246 | 0.0986583533028 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
R/G | 2400 | Ig-13 | 45 | rs765593704 | 0.6766 | -0.979 | 1.0 | D | 0.619 | 0.645 | 0.678023017383 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
R/G | 2400 | Ig-13 | 45 | rs765593704 | 0.6766 | -0.979 | 1.0 | D | 0.619 | 0.645 | 0.678023017383 | gnomAD-4.0.0 | 3.1811E-06 | None | None | None | None | N | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 0 | 0 | 2.85662E-06 | 0 | 0 |
R/K | 2400 | Ig-13 | 45 | None | 0.2019 | None | 0.997 | D | 0.476 | 0.55 | 0.698733648705 | gnomAD-4.0.0 | 3.18109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86549E-05 | 0 |
R/S | 2400 | Ig-13 | 45 | None | 0.8473 | None | 1.0 | D | 0.633 | 0.581 | 0.483521307902 | gnomAD-4.0.0 | 1.59056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85662E-06 | 0 | 0 |
R/C | 2490 | Ig-14 | 46 | rs200131545 | 0.5237 | -0.117 | 1.0 | D | 0.636 | 0.462 | 0.524271286562 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.82E-06 | 1.63239E-04 |
R/C | 2490 | Ig-14 | 46 | rs200131545 | 0.5237 | -0.117 | 1.0 | D | 0.636 | 0.462 | 0.524271286562 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 2490 | Ig-14 | 46 | rs200131545 | 0.5237 | -0.117 | 1.0 | D | 0.636 | 0.462 | 0.524271286562 | gnomAD-4.0.0 | 9.91432E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.27125E-05 | 0 | 1.60041E-05 |
R/H | 2490 | Ig-14 | 46 | rs148920986 | 0.2485 | -1.239 | 1.0 | N | 0.554 | 0.383 | None | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 4.01E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 3.88E-05 | 1.38543E-04 |
R/H | 2490 | Ig-14 | 46 | rs148920986 | 0.2485 | -1.239 | 1.0 | N | 0.554 | 0.383 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 7.35E-05 | 0 | 0 |
R/H | 2490 | Ig-14 | 46 | rs148920986 | 0.2485 | -1.239 | 1.0 | N | 0.554 | 0.383 | None | gnomAD-4.0.0 | 1.7348E-05 | None | None | None | None | N | None | 1.33298E-05 | 1.66683E-05 | None | 0 | 2.22955E-05 | None | 0 | 0 | 1.94921E-05 | 0 | 3.1998E-05 |
R/L | 2490 | Ig-14 | 46 | rs148920986 | 0.7206 | 0.378 | 0.996 | D | 0.473 | 0.5 | None | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 1.23062E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/L | 2490 | Ig-14 | 46 | rs148920986 | 0.7206 | 0.378 | 0.996 | D | 0.473 | 0.5 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/L | 2490 | Ig-14 | 46 | rs148920986 | 0.7206 | 0.378 | 0.996 | D | 0.473 | 0.5 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
R/L | 2490 | Ig-14 | 46 | rs148920986 | 0.7206 | 0.378 | 0.996 | D | 0.473 | 0.5 | None | gnomAD-4.0.0 | 4.95657E-06 | None | None | None | None | N | None | 7.99787E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.1998E-05 |
R/P | 2490 | Ig-14 | 46 | None | 0.9786 | None | 1.0 | D | 0.553 | 0.597 | 0.449283877778 | gnomAD-4.0.0 | 2.05233E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69796E-06 | 0 | 0 |
K/Q | 2577 | Ig-15 | 45 | None | 0.3281 | None | 1.0 | D | 0.703 | 0.305 | 0.236890367714 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
K/R | 2577 | Ig-15 | 45 | rs1312348465 | 0.1149 | -0.358 | 0.999 | N | 0.525 | 0.257 | 0.288727942641 | gnomAD-2.1.1 | 7.99E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
K/R | 2577 | Ig-15 | 45 | rs1312348465 | 0.1149 | -0.358 | 0.999 | N | 0.525 | 0.257 | 0.288727942641 | gnomAD-4.0.0 | 9.54651E-06 | None | None | None | None | N | None | 0 | 1.14432E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02316E-05 |
K/N | 2752 | Ig-17 | 46 | rs1253422827 | 0.6078 | -0.913 | 1.0 | D | 0.7 | 0.484 | 0.40417439687 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
K/N | 2752 | Ig-17 | 46 | rs1253422827 | 0.6078 | -0.913 | 1.0 | D | 0.7 | 0.484 | 0.40417439687 | gnomAD-4.0.0 | 3.18098E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
K/N | 3013 | Ig-20 | 45 | None | 0.8125 | None | 0.117 | N | 0.317 | 0.073 | 0.0762999501168 | gnomAD-4.0.0 | 6.84088E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99295E-07 | 0 | 0 |
R/G | 3102 | Ig-21 | 45 | None | 0.5863 | None | 0.996 | D | 0.435 | 0.624 | 0.690363523209 | gnomAD-4.0.0 | 1.59055E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02151E-05 |
R/K | 3102 | Ig-21 | 45 | None | 0.2325 | None | 0.991 | N | 0.399 | 0.357 | 0.394384168047 | gnomAD-4.0.0 | 1.59056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85651E-06 | 0 | 0 |
R/P | 3193 | Ig-22 | 47 | None | 0.9332 | None | 1.0 | D | 0.664 | 0.718 | 0.671041724158 | gnomAD-4.0.0 | 6.84089E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99311E-07 | 0 | 0 |
R/Q | 3193 | Ig-22 | 47 | rs1034071730 | 0.3149 | -0.164 | 1.0 | D | 0.684 | 0.551 | 0.467585353272 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.63239E-04 |
R/Q | 3193 | Ig-22 | 47 | rs1034071730 | 0.3149 | -0.164 | 1.0 | D | 0.684 | 0.551 | 0.467585353272 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/Q | 3193 | Ig-22 | 47 | rs1034071730 | 0.3149 | -0.164 | 1.0 | D | 0.684 | 0.551 | 0.467585353272 | gnomAD-4.0.0 | 1.98273E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22886E-05 | None | 0 | 0 | 2.37289E-05 | 0 | 4.80138E-05 |
K/R | 3284 | Ig-23 | 46 | rs147903846 | 0.2944 | -0.122 | 0.999 | N | 0.523 | 0.204 | None | gnomAD-2.1.1 | 5.67E-05 | None | None | None | None | N | None | 4.01E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.08699E-04 | 0 |
K/R | 3284 | Ig-23 | 46 | rs147903846 | 0.2944 | -0.122 | 0.999 | N | 0.523 | 0.204 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 8.82E-05 | 0 | 4.78011E-04 |
K/R | 3284 | Ig-23 | 46 | rs147903846 | 0.2944 | -0.122 | 0.999 | N | 0.523 | 0.204 | None | gnomAD-4.0.0 | 9.04528E-05 | None | None | None | None | N | None | 1.33255E-05 | 0 | None | 0 | 0 | None | 0 | 3.30142E-04 | 1.13562E-04 | 0 | 1.43982E-04 |
D/E | 3510 | Ig-25 | 46 | None | 0.261 | None | None | None | None | 0.033 | None | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
D/Y | 3510 | Ig-25 | 46 | rs770135769 | 0.4051 | 0.71 | None | None | None | 0.24 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
D/Y | 3510 | Ig-25 | 46 | rs770135769 | 0.4051 | 0.71 | None | None | None | 0.24 | None | gnomAD-4.0.0 | 2.56212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39287E-06 | 1.33998E-05 | 0 |
R/K | 3705 | Ig-26 | 46 | rs2086934731 | 0.1528 | None | None | None | None | 0.074 | None | gnomAD-4.0.0 | 6.84195E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99442E-07 | 0 | 0 |
R/T | 3705 | Ig-26 | 46 | None | 0.2953 | None | None | None | None | 0.151 | None | gnomAD-4.0.0 | 6.84195E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
K/E | 4649 | Ig-29 | 44 | rs1060500392 | 0.1405 | None | None | N | 0.047 | 0.107 | 0.136095386433 | gnomAD-4.0.0 | 6.84606E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09924E-06 | 0 | 1.65772E-05 |
K/N | 4649 | Ig-29 | 44 | rs1574063706 | 0.2082 | None | 0.001 | N | 0.072 | 0.147 | 0.117506650769 | gnomAD-4.0.0 | 1.36939E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00019E-07 | 0 | 1.65815E-05 |
K/M | 4745 | Ig-30 | 46 | None | 0.8198 | None | 1.0 | N | 0.703 | 0.399 | 0.252162846088 | gnomAD-4.0.0 | 1.59166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85847E-06 | 0 | 0 |
K/N | 4745 | Ig-30 | 46 | rs756868442 | 0.8814 | None | 1.0 | N | 0.728 | 0.237 | 0.154104182512 | gnomAD-4.0.0 | 6.8428E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99489E-07 | 0 | 0 |
K/R | 4745 | Ig-30 | 46 | rs778762576 | 0.121 | -0.18 | 0.999 | N | 0.522 | 0.244 | 0.188950314367 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
K/R | 4745 | Ig-30 | 46 | rs778762576 | 0.121 | -0.18 | 0.999 | N | 0.522 | 0.244 | 0.188950314367 | gnomAD-4.0.0 | 1.59166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78071E-05 | None | 0 | 0 | 0 | 0 | 0 |
N/H | 4840 | Ig-31 | 46 | rs199997460 | 0.0795 | -1.133 | None | N | 0.174 | 0.042 | None | gnomAD-2.1.1 | 7.85E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 7.99E-05 | 1.48204E-04 | 0 |
N/H | 4840 | Ig-31 | 46 | rs199997460 | 0.0795 | -1.133 | None | N | 0.174 | 0.042 | None | gnomAD-3.1.2 | 7.89E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 1.88324E-04 | 0 | 1.32298E-04 | 0 | 0 |
N/H | 4840 | Ig-31 | 46 | rs199997460 | 0.0795 | -1.133 | None | N | 0.174 | 0.042 | None | gnomAD-4.0.0 | 1.25175E-04 | None | None | None | None | N | None | 0 | 1.66722E-05 | None | 0 | 0 | None | 1.24961E-04 | 0 | 1.59347E-04 | 0 | 8.00615E-05 |
N/K | 4840 | Ig-31 | 46 | rs1162232624 | 0.1481 | None | None | N | 0.18 | 0.097 | 0.0551355673512 | gnomAD-4.0.0 | 1.59111E-06 | None | None | None | None | N | None | 5.65291E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
N/T | 4840 | Ig-31 | 46 | rs779078589 | 0.0986 | -0.687 | None | N | 0.16 | 0.062 | 0.104622674875 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 8.49E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.40331E-04 |
N/T | 4840 | Ig-31 | 46 | rs779078589 | 0.0986 | -0.687 | None | N | 0.16 | 0.062 | 0.104622674875 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
N/T | 4840 | Ig-31 | 46 | rs779078589 | 0.0986 | -0.687 | None | N | 0.16 | 0.062 | 0.104622674875 | gnomAD-4.0.0 | 2.56203E-06 | None | None | None | None | N | None | 0 | 1.69509E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84398E-05 |
D/Y | 4933 | Ig-32 | 46 | rs984284016 | 0.2106 | 0.115 | 1.0 | N | 0.718 | 0.365 | 0.439445477881 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
D/Y | 4933 | Ig-32 | 46 | rs984284016 | 0.2106 | 0.115 | 1.0 | N | 0.718 | 0.365 | 0.439445477881 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
D/Y | 4933 | Ig-32 | 46 | rs984284016 | 0.2106 | 0.115 | 1.0 | N | 0.718 | 0.365 | 0.439445477881 | gnomAD-4.0.0 | 6.57056E-06 | None | None | None | None | N | None | 2.41173E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
T/I | 5027 | Ig-33 | 47 | rs778591734 | 0.1732 | -0.224 | 0.996 | N | 0.381 | 0.287 | 0.329020015101 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.56E-05 | 0 |
T/K | 5027 | Ig-33 | 47 | None | 0.1088 | None | 0.061 | N | 0.187 | 0.219 | 0.1749357433 | gnomAD-4.0.0 | 1.36849E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52118E-05 | None | 0 | 0 | 0 | 0 | 1.65673E-05 |
K/N | 5213 | Ig-35 | 46 | rs2080952653 | 0.1461 | None | 0.005 | N | 0.087 | 0.065 | 0.0666544352282 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/N | 5213 | Ig-35 | 46 | rs2080952653 | 0.1461 | None | 0.005 | N | 0.087 | 0.065 | 0.0666544352282 | gnomAD-4.0.0 | 6.57445E-06 | None | None | None | None | N | None | 2.41429E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/T | 5402 | Ig-37 | 46 | rs886042411 | 0.1382 | -0.706 | 0.024 | N | 0.317 | 0.241 | 0.272205846399 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
R/T | 5402 | Ig-37 | 46 | rs886042411 | 0.1382 | -0.706 | 0.024 | N | 0.317 | 0.241 | 0.272205846399 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
R/T | 5402 | Ig-37 | 46 | rs886042411 | 0.1382 | -0.706 | 0.024 | N | 0.317 | 0.241 | 0.272205846399 | gnomAD-4.0.0 | 7.43721E-06 | None | None | None | None | N | None | 1.33479E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32395E-06 | 0 | 0 |
S/G | 5495 | Ig-38 | 46 | None | 0.0738 | None | 0.012 | N | 0.293 | 0.1 | 0.112648838833 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
S/N | 5495 | Ig-38 | 46 | rs1183828555 | 0.0617 | 0.122 | None | N | 0.265 | 0.038 | 0.0401082797425 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
S/N | 5495 | Ig-38 | 46 | rs1183828555 | 0.0617 | 0.122 | None | N | 0.265 | 0.038 | 0.0401082797425 | gnomAD-4.0.0 | 1.36851E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.799E-06 | 0 | 0 |
S/T | 5495 | Ig-38 | 46 | rs1183828555 | 0.0789 | -0.013 | None | N | 0.105 | 0.047 | 0.0482279557977 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
N/S | 5775 | Ig-41 | 46 | rs1347227022 | 0.0793 | -0.294 | 0.549 | N | 0.373 | 0.144 | 0.126345400529 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.87687E-04 | 0 | 0 |
N/S | 5775 | Ig-41 | 46 | rs1347227022 | 0.0793 | -0.294 | 0.549 | N | 0.373 | 0.144 | 0.126345400529 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.42E-05 | 0 | 0 | 0 | 0 |
N/S | 5775 | Ig-41 | 46 | rs1347227022 | 0.0793 | -0.294 | 0.549 | N | 0.373 | 0.144 | 0.126345400529 | gnomAD-4.0.0 | 5.1246E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.27569E-05 | 0 | 0 | 0 | 0 |
N/T | 5775 | Ig-41 | 46 | None | 0.1113 | None | 0.712 | N | 0.388 | 0.149 | 0.186928172975 | gnomAD-4.0.0 | 4.77395E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71647E-06 | 1.43279E-05 | 0 |
K/E | 6244 | Ig-46 | 46 | None | 0.6127 | None | 0.996 | N | 0.418 | 0.29 | 0.277317399466 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
K/N | 6244 | Ig-46 | 46 | None | 0.6365 | None | 0.884 | N | 0.257 | 0.179 | 0.0297737177859 | gnomAD-4.0.0 | 1.5916E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77316E-05 | None | 0 | 0 | 0 | 0 | 0 |
K/R | 6244 | Ig-46 | 46 | rs1448766260 | 0.1138 | -0.378 | 0.998 | N | 0.501 | 0.186 | 0.17258766438 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
K/R | 6244 | Ig-46 | 46 | rs1448766260 | 0.1138 | -0.378 | 0.998 | N | 0.501 | 0.186 | 0.17258766438 | gnomAD-4.0.0 | 1.5916E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0248E-05 |
N/S | 6337 | Ig-47 | 46 | None | 0.0841 | None | 0.065 | N | 0.122 | 0.105 | 0.0884992946249 | gnomAD-4.0.0 | 1.59328E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43484E-05 | 0 |
Y/C | 6430 | Ig-48 | 46 | rs781726929 | 0.3032 | -0.198 | 0.997 | N | 0.363 | 0.423 | 0.430808444494 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23989E-04 | None | 0 | None | 0 | 0 | 0 |
Y/C | 6430 | Ig-48 | 46 | rs781726929 | 0.3032 | -0.198 | 0.997 | N | 0.363 | 0.423 | 0.430808444494 | gnomAD-4.0.0 | 2.7377E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.04898E-05 | None | 0 | 0 | 1.79923E-06 | 0 | 0 |
K/E | 6619 | Ig-50 | 46 | rs1060500450 | 0.1078 | 0.559 | 0.052 | N | 0.279 | 0.17 | 0.20549828249 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
K/E | 6619 | Ig-50 | 46 | rs1060500450 | 0.1078 | 0.559 | 0.052 | N | 0.279 | 0.17 | 0.20549828249 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
K/E | 6619 | Ig-50 | 46 | rs1060500450 | 0.1078 | 0.559 | 0.052 | N | 0.279 | 0.17 | 0.20549828249 | gnomAD-4.0.0 | 1.1536E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.15532E-05 | 0 | 0 |
K/T | 6619 | Ig-50 | 46 | rs368720026 | 0.1028 | -0.275 | None | N | 0.109 | 0.105 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65728E-04 |
K/T | 6619 | Ig-50 | 46 | rs368720026 | 0.1028 | -0.275 | None | N | 0.109 | 0.105 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 1.93087E-04 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/T | 6619 | Ig-50 | 46 | rs368720026 | 0.1028 | -0.275 | None | N | 0.109 | 0.105 | None | gnomAD-4.0.0 | 1.79463E-05 | None | None | None | None | N | None | 1.69279E-04 | 5.08613E-05 | None | 0 | 0 | None | 0 | 0 | 2.39479E-06 | 0 | 0 |
K/N | 6713 | Ig-51 | 47 | rs375668907 | 0.4283 | -0.346 | 0.099 | N | 0.159 | 0.08 | 0.0611884634855 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
K/N | 6713 | Ig-51 | 47 | rs375668907 | 0.4283 | -0.346 | 0.099 | N | 0.159 | 0.08 | 0.0611884634855 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
K/N | 6713 | Ig-51 | 47 | rs375668907 | 0.4283 | -0.346 | 0.099 | N | 0.159 | 0.08 | 0.0611884634855 | gnomAD-4.0.0 | 1.5498E-05 | None | None | None | None | N | None | 0 | 3.33723E-05 | None | 0 | 2.23085E-05 | None | 0 | 0 | 1.78049E-05 | 0 | 1.60159E-05 |
K/T | 6713 | Ig-51 | 47 | rs1410340266 | 0.1998 | -0.607 | 0.712 | N | 0.409 | 0.336 | 0.257292322809 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
K/T | 6713 | Ig-51 | 47 | rs1410340266 | 0.1998 | -0.607 | 0.712 | N | 0.409 | 0.336 | 0.257292322809 | gnomAD-4.0.0 | 3.18491E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86056E-06 | 0 | 3.0259E-05 |
K/N | 6806 | Ig-52 | 46 | rs768932465 | 0.8154 | -0.628 | 0.957 | N | 0.213 | 0.272 | 0.237489013734 | gnomAD-2.1.1 | 1.00171E-04 | None | None | None | None | N | None | 0 | 2.8393E-04 | None | 0 | 0 | None | 0 | None | 0 | 1.40887E-04 | 0 |
K/N | 6806 | Ig-52 | 46 | rs768932465 | 0.8154 | -0.628 | 0.957 | N | 0.213 | 0.272 | 0.237489013734 | gnomAD-3.1.2 | 8.54E-05 | None | None | None | None | N | None | 2.41E-05 | 1.96644E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.32306E-04 | 0 | 0 |
K/N | 6806 | Ig-52 | 46 | rs768932465 | 0.8154 | -0.628 | 0.957 | N | 0.213 | 0.272 | 0.237489013734 | gnomAD-4.0.0 | 9.91814E-05 | None | None | None | None | N | None | 1.33308E-05 | 3.00411E-04 | None | 0 | 0 | None | 0 | 1.6518E-04 | 1.1361E-04 | 1.09851E-05 | 8.00871E-05 |
K/T | 6806 | Ig-52 | 46 | None | 0.6898 | None | 0.995 | N | 0.465 | 0.485 | 0.575946966538 | gnomAD-4.0.0 | 1.59285E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41546E-04 | 0 | 0 | 0 |
N/K | 6900 | Ig-53 | 47 | None | 0.495 | None | 0.998 | N | 0.564 | 0.197 | 0.0920862733494 | gnomAD-4.0.0 | 3.42199E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49822E-06 | 0 | 0 |
N/S | 6900 | Ig-53 | 47 | rs1389235832 | 0.1683 | None | 0.998 | N | 0.383 | 0.217 | 0.117506650769 | gnomAD-4.0.0 | 1.59226E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86015E-06 | 0 | 0 |
R/G | 7182 | Ig-56 | 46 | None | 0.0759 | None | 0.008 | N | 0.206 | 0.056 | 0.223146558224 | gnomAD-4.0.0 | 6.84392E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9962E-07 | 0 | 0 |
R/Q | 7182 | Ig-56 | 46 | rs200447686 | 0.0703 | 0.088 | None | N | 0.115 | 0.068 | None | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | N | None | 1.2409E-04 | 5.67E-05 | None | 0 | 1.02796E-04 | None | 0 | None | 0 | 5.47E-05 | 1.40805E-04 |
R/Q | 7182 | Ig-56 | 46 | rs200447686 | 0.0703 | 0.088 | None | N | 0.115 | 0.068 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 1.20703E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 4.79386E-04 |
R/Q | 7182 | Ig-56 | 46 | rs200447686 | 0.0703 | 0.088 | None | N | 0.115 | 0.068 | None | gnomAD-4.0.0 | 7.00453E-05 | None | None | None | None | N | None | 1.20205E-04 | 1.1676E-04 | None | 0 | 4.4615E-05 | None | 0 | 4.93259E-04 | 7.37552E-05 | 0 | 8.01077E-05 |
R/W | 7182 | Ig-56 | 46 | rs727504736 | 0.1064 | -0.319 | 0.941 | N | 0.322 | 0.14 | None | gnomAD-2.1.1 | 9.26E-05 | None | None | None | None | N | None | 6.47E-05 | 5.23073E-04 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 2.67E-05 | 0 |
R/W | 7182 | Ig-56 | 46 | rs727504736 | 0.1064 | -0.319 | 0.941 | N | 0.322 | 0.14 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.41E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
R/W | 7182 | Ig-56 | 46 | rs727504736 | 0.1064 | -0.319 | 0.941 | N | 0.322 | 0.14 | None | gnomAD-4.0.0 | 4.27725E-05 | None | None | None | None | N | None | 2.67151E-05 | 4.17056E-04 | None | 0 | 2.23085E-05 | None | 0 | 0 | 3.30631E-05 | 0 | 3.2039E-05 |
E/A | 7368 | Ig-58 | 46 | rs1420368632 | 0.089 | -0.715 | 0.454 | N | 0.292 | 0.078 | 0.18995819373 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
E/A | 7368 | Ig-58 | 46 | rs1420368632 | 0.089 | -0.715 | 0.454 | N | 0.292 | 0.078 | 0.18995819373 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
E/A | 7368 | Ig-58 | 46 | rs1420368632 | 0.089 | -0.715 | 0.454 | N | 0.292 | 0.078 | 0.18995819373 | gnomAD-4.0.0 | 8.6782E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18687E-05 | 0 | 0 |
E/Q | 7368 | Ig-58 | 46 | None | 0.1129 | None | 0.801 | N | 0.381 | 0.162 | 0.132336055621 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
N/D | 7464 | Ig-59 | 46 | rs879082137 | 0.2652 | None | 0.805 | N | 0.437 | 0.161 | 0.233785782151 | gnomAD-4.0.0 | 1.36869E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79925E-05 | 0 | 0 |
N/D | 7560 | Ig-60 | 46 | None | 0.5236 | None | 0.943 | N | 0.403 | 0.218 | 0.173771789658 | gnomAD-4.0.0 | 1.59173E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85941E-06 | 0 | 0 |
N/D | 7841 | Ig-63 | 47 | rs753072306 | 0.1438 | 0.068 | 0.256 | N | 0.423 | 0.11 | 0.166414681773 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
N/Y | 7841 | Ig-63 | 47 | rs753072306 | 0.1853 | -0.666 | 0.997 | N | 0.491 | 0.436 | 0.228597637076 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.58643E-04 | None | 0 | None | 0 | 0 | 0 |
N/Y | 7841 | Ig-63 | 47 | rs753072306 | 0.1853 | -0.666 | 0.997 | N | 0.491 | 0.436 | 0.228597637076 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92456E-04 | None | 0 | 0 | 0 | 0 | 0 |
N/Y | 7841 | Ig-63 | 47 | rs753072306 | 0.1853 | -0.666 | 0.997 | N | 0.491 | 0.436 | 0.228597637076 | gnomAD-4.0.0 | 7.43641E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.45043E-04 | None | 0 | 0 | 0 | 0 | 1.60123E-05 |
S/L | 8123 | Ig-66 | 46 | rs879096365 | 0.0866 | -0.219 | 0.062 | N | 0.349 | 0.104 | None | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
S/L | 8123 | Ig-66 | 46 | rs879096365 | 0.0866 | -0.219 | 0.062 | N | 0.349 | 0.104 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
S/L | 8123 | Ig-66 | 46 | rs879096365 | 0.0866 | -0.219 | 0.062 | N | 0.349 | 0.104 | None | gnomAD-4.0.0 | 9.2958E-06 | None | None | None | None | N | None | 5.3416E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32398E-06 | 0 | 0 |
S/P | 8123 | Ig-66 | 46 | rs1407865752 | 0.1521 | -0.286 | 0.317 | N | 0.43 | 0.102 | 0.0920862733494 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
S/P | 8123 | Ig-66 | 46 | rs1407865752 | 0.1521 | -0.286 | 0.317 | N | 0.43 | 0.102 | 0.0920862733494 | gnomAD-4.0.0 | 1.5913E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77408E-05 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 8216 | Ig-67 | 46 | rs561781856 | 0.0687 | -0.458 | None | N | 0.073 | 0.094 | 0.0611884634855 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 8216 | Ig-67 | 46 | rs561781856 | 0.0687 | -0.458 | None | N | 0.073 | 0.094 | 0.0611884634855 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
R/K | 8216 | Ig-67 | 46 | rs561781856 | 0.0687 | -0.458 | None | N | 0.073 | 0.094 | 0.0611884634855 | gnomAD-4.0.0 | 2.56192E-06 | None | None | None | None | N | None | 0 | 3.38857E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 8216 | Ig-67 | 46 | None | 0.14 | None | None | N | 0.149 | 0.131 | 0.0297737177859 | gnomAD-4.0.0 | 6.84222E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99486E-07 | 0 | 0 |
A/E | 8309 | Ig-68 | 46 | rs186598275 | 0.256 | -0.496 | 0.965 | N | 0.345 | 0.26 | 0.445007932271 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
A/E | 8309 | Ig-68 | 46 | rs186598275 | 0.256 | -0.496 | 0.965 | N | 0.345 | 0.26 | 0.445007932271 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 0 | 0 | 0 |
A/E | 8309 | Ig-68 | 46 | rs186598275 | 0.256 | -0.496 | 0.965 | N | 0.345 | 0.26 | 0.445007932271 | gnomAD-4.0.0 | 6.5678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93424E-04 | None | 0 | 0 | 0 | 0 | 0 |
A/V | 8309 | Ig-68 | 46 | rs186598275 | 0.1359 | -0.202 | 0.965 | N | 0.323 | 0.259 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
A/V | 8309 | Ig-68 | 46 | rs186598275 | 0.1359 | -0.202 | 0.965 | N | 0.323 | 0.259 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
A/V | 8309 | Ig-68 | 46 | rs186598275 | 0.1359 | -0.202 | 0.965 | N | 0.323 | 0.259 | None | gnomAD-4.0.0 | 6.5678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4705E-05 | 0 | 0 |
N/K | 8405 | Ig-69 | 46 | rs371923232 | 0.4957 | -0.094 | 0.649 | N | 0.205 | 0.141 | 0.168933306366 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
N/K | 8405 | Ig-69 | 46 | rs371923232 | 0.4957 | -0.094 | 0.649 | N | 0.205 | 0.141 | 0.168933306366 | gnomAD-4.0.0 | 1.11566E-05 | None | None | None | None | N | None | 1.33483E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35637E-05 | 0 | 1.60154E-05 |
N/K | 8501 | Ig-70 | 46 | rs758559820 | 0.8055 | 0.453 | 0.388 | N | 0.178 | 0.087 | 0.115124310173 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 1.65782E-04 |
N/K | 8501 | Ig-70 | 46 | rs758559820 | 0.8055 | 0.453 | 0.388 | N | 0.178 | 0.087 | 0.115124310173 | gnomAD-4.0.0 | 5.47423E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 8.11557E-05 | 1.657E-05 |
K/N | 8595 | Ig-71 | 47 | None | 0.496 | None | 0.019 | N | 0.073 | 0.06 | 0.0806252709748 | gnomAD-4.0.0 | 1.59172E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85914E-06 | 0 | 0 |
K/Q | 8595 | Ig-71 | 47 | None | 0.2158 | None | 0.006 | N | 0.189 | 0.184 | 0.104622674875 | gnomAD-4.0.0 | 1.36859E-06 | None | None | None | None | N | None | 0 | 4.47507E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/R | 8595 | Ig-71 | 47 | rs774140425 | 0.0849 | -0.301 | 0.241 | N | 0.285 | 0.09 | 0.119812018005 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 1.16117E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
K/R | 8595 | Ig-71 | 47 | rs774140425 | 0.0849 | -0.301 | 0.241 | N | 0.285 | 0.09 | 0.119812018005 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/R | 8595 | Ig-71 | 47 | rs774140425 | 0.0849 | -0.301 | 0.241 | N | 0.285 | 0.09 | 0.119812018005 | gnomAD-4.0.0 | 1.66584E-05 | None | None | None | None | N | None | 0 | 1.01764E-04 | None | 0 | 0 | None | 0 | 0 | 7.18119E-06 | 0 | 1.13824E-04 |
N/S | 8782 | Ig-73 | 47 | rs727504895 | 0.0864 | None | 0.03 | N | 0.115 | 0.094 | 0.0846915920261 | gnomAD-4.0.0 | 1.36848E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51915E-05 | None | 0 | 0 | 8.99501E-07 | 0 | 0 |
N/Y | 8782 | Ig-73 | 47 | rs1017848590 | 0.2031 | None | 1.0 | N | 0.52 | 0.35 | 0.39724302092 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
N/Y | 8782 | Ig-73 | 47 | rs1017848590 | 0.2031 | None | 1.0 | N | 0.52 | 0.35 | 0.39724302092 | gnomAD-4.0.0 | 9.29567E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.1867E-05 | 0 | 1.60118E-05 |
K/I | 8875 | Ig-74 | 46 | rs1472784946 | 0.5713 | None | 1.0 | N | 0.641 | 0.454 | 0.496036935653 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
K/I | 8875 | Ig-74 | 46 | rs1472784946 | 0.5713 | None | 1.0 | N | 0.641 | 0.454 | 0.496036935653 | gnomAD-4.0.0 | 1.31463E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94048E-05 | 0 | 0 |
K/E | 8971 | Ig-75 | 46 | rs373877046 | 0.5852 | 0.218 | 0.92 | N | 0.364 | 0.257 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
K/E | 8971 | Ig-75 | 46 | rs373877046 | 0.5852 | 0.218 | 0.92 | N | 0.364 | 0.257 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
K/E | 8971 | Ig-75 | 46 | rs373877046 | 0.5852 | 0.218 | 0.92 | N | 0.364 | 0.257 | None | gnomAD-4.0.0 | 1.98335E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.71257E-05 | 0 | 0 |
K/N | 8971 | Ig-75 | 46 | None | 0.7184 | None | 0.061 | N | 0.126 | 0.123 | 0.0611884634855 | gnomAD-4.0.0 | 2.73724E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59811E-06 | 0 | 0 |
R/G | 9635 | Ig-82 | 46 | rs397517531 | 0.1689 | None | 0.024 | None | 0.287 | 0.199 | 0.310458034454 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
R/G | 9635 | Ig-82 | 46 | rs397517531 | 0.1689 | None | 0.024 | None | 0.287 | 0.199 | 0.310458034454 | gnomAD-4.0.0 | 3.42088E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79882E-06 | 2.31884E-05 | 1.65645E-05 |
R/C | 9744 | Ig-83 | 47 | rs375266859 | 0.9563 | -0.896 | 1.0 | None | 0.711 | 0.414 | None | gnomAD-2.1.1 | 5.35E-05 | None | None | None | None | N | None | 0 | 0 | None | 1.93162E-04 | 0 | None | 3.27E-05 | None | 0 | 9.34E-05 | 0 |
R/C | 9744 | Ig-83 | 47 | rs375266859 | 0.9563 | -0.896 | 1.0 | None | 0.711 | 0.414 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88351E-04 | 0 | None | 0 | 0 | 8.82E-05 | 2.07814E-04 | 0 |
R/C | 9744 | Ig-83 | 47 | rs375266859 | 0.9563 | -0.896 | 1.0 | None | 0.711 | 0.414 | None | gnomAD-4.0.0 | 4.27588E-05 | None | None | None | None | N | None | 0 | 3.33456E-05 | None | 1.35153E-04 | 0 | None | 0 | 0 | 5.17018E-05 | 1.09808E-05 | 1.60092E-05 |
R/G | 9744 | Ig-83 | 47 | rs375266859 | 0.9663 | None | 1.0 | None | 0.675 | 0.531 | 0.418964662724 | gnomAD-4.0.0 | 6.84162E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99425E-07 | 0 | 0 |
R/H | 9744 | Ig-83 | 47 | rs760305440 | 0.7704 | -1.388 | 1.0 | None | 0.675 | 0.502 | None | gnomAD-2.1.1 | 1.78E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.12E-05 | 0 |
R/H | 9744 | Ig-83 | 47 | rs760305440 | 0.7704 | -1.388 | 1.0 | None | 0.675 | 0.502 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 4.83E-05 | 1.30993E-04 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
R/H | 9744 | Ig-83 | 47 | rs760305440 | 0.7704 | -1.388 | 1.0 | None | 0.675 | 0.502 | None | Arimura (2009) Lopes (2013) | None | HCM | het | None | None | N | Increases binding of TTN to CARP (Co-IP assay); alters subcellular localisation of CARP (Myc-tag) | None | None | None | None | None | None | None | None | None | None | None |
R/H | 9744 | Ig-83 | 47 | rs760305440 | 0.7704 | -1.388 | 1.0 | None | 0.675 | 0.502 | None | gnomAD-4.0.0 | 5.26723E-05 | None | None | None | None | N | None | 2.67044E-05 | 5.00067E-05 | None | 0 | 2.22787E-05 | None | 0 | 1.64366E-04 | 6.10253E-05 | 2.19573E-05 | 6.40451E-05 |
K/N | 9946 | Ig-84 | 47 | rs1181662412 | 0.7959 | -0.464 | 0.993 | None | 0.686 | 0.287 | 0.119812018005 | gnomAD-2.1.1 | 8.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.126E-04 | None | 0 | None | 0 | 0 | 0 |
K/N | 9946 | Ig-84 | 47 | rs1181662412 | 0.7959 | -0.464 | 0.993 | None | 0.686 | 0.287 | 0.119812018005 | gnomAD-4.0.0 | 1.59444E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77331E-05 | None | 0 | 0 | 0 | 0 | 0 |
K/T | 9946 | Ig-84 | 47 | rs1268571982 | 0.5363 | -0.684 | 0.993 | None | 0.684 | 0.414 | 0.330589388543 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.63E-05 | None | 0 | None | 0 | 0 | 0 |
K/N | 13731 | Ig-87 | 48 | rs559968058 | 0.9709 | -0.473 | 1.0 | N | 0.703 | 0.265 | 0.184867976434 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
K/N | 13731 | Ig-87 | 48 | rs559968058 | 0.9709 | -0.473 | 1.0 | N | 0.703 | 0.265 | 0.184867976434 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
K/N | 13731 | Ig-87 | 48 | rs559968058 | 0.9709 | -0.473 | 1.0 | N | 0.703 | 0.265 | 0.184867976434 | gnomAD-4.0.0 | 6.57644E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47106E-05 | 0 | 0 |
R/G | 13825 | Ig-88 | 46 | None | 0.3002 | None | 0.058 | N | 0.345 | 0.105 | 0.0884992946249 | gnomAD-4.0.0 | 4.10659E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39793E-06 | 0 | 0 |
R/L | 13825 | Ig-88 | 46 | rs727504774 | 0.2845 | 0.088 | 0.058 | N | 0.395 | 0.064 | 0.0884992946249 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.65E-05 | 8.9E-06 | 0 |
R/L | 13825 | Ig-88 | 46 | rs727504774 | 0.2845 | 0.088 | 0.058 | N | 0.395 | 0.064 | 0.0884992946249 | gnomAD-4.0.0 | 6.84428E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99648E-07 | 0 | 0 |
R/Q | 13825 | Ig-88 | 46 | rs727504774 | 0.1159 | -0.209 | 0.142 | N | 0.272 | 0.057 | 0.0611884634855 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 1.65399E-04 | 5.66E-05 | None | 0 | 5.18E-05 | None | 0 | None | 0 | 0 | 0 |
R/Q | 13825 | Ig-88 | 46 | rs727504774 | 0.1159 | -0.209 | 0.142 | N | 0.272 | 0.057 | 0.0611884634855 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 7.25E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/Q | 13825 | Ig-88 | 46 | rs727504774 | 0.1159 | -0.209 | 0.142 | N | 0.272 | 0.057 | 0.0611884634855 | gnomAD-4.0.0 | 2.60376E-05 | None | None | None | None | N | None | 9.35254E-05 | 3.33667E-05 | None | 0 | 2.23754E-05 | None | 0 | 1.64582E-04 | 2.54339E-05 | 0 | 1.60154E-05 |
K/Q | 13920 | Ig-89 | 45 | None | 0.5278 | None | 0.999 | D | 0.724 | 0.355 | 0.215109475489 | gnomAD-4.0.0 | 6.93226E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.08102E-07 | 0 | 0 |
K/R | 13920 | Ig-89 | 45 | rs751156425 | 0.1391 | 0.016 | 0.997 | N | 0.637 | 0.194 | 0.219573609325 | gnomAD-2.1.1 | 9.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 7.25E-05 | None | 0 | 0 | 0 |
K/R | 13920 | Ig-89 | 45 | rs751156425 | 0.1391 | 0.016 | 0.997 | N | 0.637 | 0.194 | 0.219573609325 | gnomAD-4.0.0 | 3.281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.96824E-05 | 0 |
T/K | 14186 | Ig-92 | 45 | rs369771893 | 0.2961 | -0.619 | 1.0 | N | 0.653 | 0.427 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
T/K | 14186 | Ig-92 | 45 | rs369771893 | 0.2961 | -0.619 | 1.0 | N | 0.653 | 0.427 | None | gnomAD-4.0.0 | 2.47945E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39104E-06 | 0 | 0 |
T/P | 14186 | Ig-92 | 45 | rs1187615662 | 0.4122 | -0.348 | 1.0 | N | 0.625 | 0.486 | 0.32471235697 | gnomAD-4.0.0 | 1.59192E-06 | None | None | None | None | N | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
T/R | 14186 | Ig-92 | 45 | None | 0.2714 | None | 1.0 | N | 0.626 | 0.417 | 0.324436698001 | gnomAD-4.0.0 | 6.84335E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99616E-07 | 0 | 0 |
K/N | 14274 | Ig-93 | 44 | rs2060064294 | 0.5391 | None | 0.001 | N | 0.129 | 0.033 | 0.0401082797425 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
K/N | 14274 | Ig-93 | 44 | rs2060064294 | 0.5391 | None | 0.001 | N | 0.129 | 0.033 | 0.0401082797425 | gnomAD-4.0.0 | 6.57384E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4708E-05 | 0 | 0 |
D/N | 14363 | Ig-94 | 45 | rs745979661 | 0.0843 | -0.212 | 0.015 | N | 0.213 | 0.094 | 0.104622674875 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
D/N | 14363 | Ig-94 | 45 | rs745979661 | 0.0843 | -0.212 | 0.015 | N | 0.213 | 0.094 | 0.104622674875 | gnomAD-4.0.0 | 1.5943E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78567E-05 | None | 0 | 0 | 0 | 0 | 0 |
D/Y | 14363 | Ig-94 | 45 | rs745979661 | 0.1955 | -0.444 | 0.994 | D | 0.674 | 0.254 | 0.418344901717 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
D/Y | 14363 | Ig-94 | 45 | rs745979661 | 0.1955 | -0.444 | 0.994 | D | 0.674 | 0.254 | 0.418344901717 | gnomAD-4.0.0 | 1.5943E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02975E-05 |
R/G | 14452 | Ig-95 | 45 | rs367791276 | 0.1635 | -1.537 | 0.024 | D | 0.255 | 0.51 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/G | 14452 | Ig-95 | 45 | rs367791276 | 0.1635 | -1.537 | 0.024 | D | 0.255 | 0.51 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/G | 14452 | Ig-95 | 45 | rs367791276 | 0.1635 | -1.537 | 0.024 | D | 0.255 | 0.51 | None | gnomAD-4.0.0 | 6.57514E-06 | None | None | None | None | N | None | 2.41301E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/I | 14452 | Ig-95 | 45 | rs528741819 | 0.1906 | -0.188 | 0.171 | D | 0.471 | 0.451 | 0.356690202451 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 2.41E-05 | 4.59016E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/I | 14452 | Ig-95 | 45 | rs528741819 | 0.1906 | -0.188 | 0.171 | D | 0.471 | 0.451 | 0.356690202451 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
R/I | 14452 | Ig-95 | 45 | rs528741819 | 0.1906 | -0.188 | 0.171 | D | 0.471 | 0.451 | 0.356690202451 | gnomAD-4.0.0 | 8.67692E-06 | None | None | None | None | N | None | 1.33308E-05 | 1.83388E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.20195E-05 |
R/K | 14452 | Ig-95 | 45 | None | 0.0665 | None | None | N | 0.066 | 0.255 | 0.128392430309 | gnomAD-4.0.0 | 6.84321E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99612E-07 | 0 | 0 |
R/S | 14452 | Ig-95 | 45 | rs374231453 | 0.3011 | -1.176 | 0.012 | D | 0.283 | 0.248 | 0.290962096972 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
R/S | 14452 | Ig-95 | 45 | rs374231453 | 0.3011 | -1.176 | 0.012 | D | 0.283 | 0.248 | 0.290962096972 | gnomAD-4.0.0 | 6.84312E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99603E-07 | 0 | 0 |
S/L | 14541 | Ig-96 | 45 | rs768180052 | 0.0774 | -0.282 | None | N | 0.154 | 0.284 | 0.149567049428 | gnomAD-2.1.1 | 8.25E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.37E-05 | None | 0 | 9.11E-06 | 0 |
S/L | 14541 | Ig-96 | 45 | rs768180052 | 0.0774 | -0.282 | None | N | 0.154 | 0.284 | 0.149567049428 | gnomAD-4.0.0 | 5.4887E-06 | None | None | None | None | N | None | 0 | 4.52202E-05 | None | 0 | 0 | None | 0 | 0 | 3.60387E-06 | 2.33907E-05 | 0 |
K/E | 14808 | Ig-99 | 44 | None | 0.1632 | None | 0.09 | N | 0.263 | 0.194 | 0.18995819373 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
K/N | 14808 | Ig-99 | 44 | rs762657962 | 0.2719 | 0.043 | 0.324 | N | 0.297 | 0.105 | 0.117506650769 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
K/N | 14808 | Ig-99 | 44 | rs762657962 | 0.2719 | 0.043 | 0.324 | N | 0.297 | 0.105 | 0.117506650769 | gnomAD-4.0.0 | 1.59544E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86466E-06 | 0 | 0 |
K/T | 14808 | Ig-99 | 44 | rs374419129 | 0.1135 | -0.31 | 0.001 | N | 0.191 | 0.126 | None | gnomAD-2.1.1 | 4.3E-05 | None | None | None | None | N | None | 1.6559E-04 | 1.99022E-04 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
K/T | 14808 | Ig-99 | 44 | rs374419129 | 0.1135 | -0.31 | 0.001 | N | 0.191 | 0.126 | None | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 2.17181E-04 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.79386E-04 |
K/T | 14808 | Ig-99 | 44 | rs374419129 | 0.1135 | -0.31 | 0.001 | N | 0.191 | 0.126 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 8E-04 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
K/T | 14808 | Ig-99 | 44 | rs374419129 | 0.1135 | -0.31 | 0.001 | N | 0.191 | 0.126 | None | gnomAD-4.0.0 | 4.89972E-05 | None | None | None | None | N | None | 6.26934E-04 | 1.16787E-04 | None | 0 | 0 | None | 0 | 3.30688E-04 | 5.08886E-06 | 1.09982E-05 | 2.56451E-04 |
R/C | 15346 | Ig-105 | 45 | rs767343871 | 0.4547 | -0.064 | 1.0 | D | 0.71 | 0.407 | 0.685456958132 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 5.17E-05 | None | 1.30813E-04 | None | 0 | 0 | 0 |
R/C | 15346 | Ig-105 | 45 | rs767343871 | 0.4547 | -0.064 | 1.0 | D | 0.71 | 0.407 | 0.685456958132 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07987E-04 | 0 |
R/C | 15346 | Ig-105 | 45 | rs767343871 | 0.4547 | -0.064 | 1.0 | D | 0.71 | 0.407 | 0.685456958132 | gnomAD-4.0.0 | 1.05446E-05 | None | None | None | None | N | None | 2.67451E-05 | 1.67084E-05 | None | 3.38455E-05 | 2.23634E-05 | None | 0 | 0 | 1.6964E-06 | 1.09878E-04 | 0 |
R/H | 15346 | Ig-105 | 45 | rs367996763 | 0.2062 | -0.959 | 1.0 | D | 0.749 | 0.453 | None | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 1.94099E-04 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
R/H | 15346 | Ig-105 | 45 | rs367996763 | 0.2062 | -0.959 | 1.0 | D | 0.749 | 0.453 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 9.66E-05 | 0 | 0 | 0 | 1.94932E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/H | 15346 | Ig-105 | 45 | rs367996763 | 0.2062 | -0.959 | 1.0 | D | 0.749 | 0.453 | None | gnomAD-4.0.0 | 1.36455E-05 | None | None | None | None | N | None | 1.06969E-04 | 5.0122E-05 | None | 0 | 2.23684E-05 | None | 0 | 0 | 7.63377E-06 | 1.09859E-05 | 0 |
K/E | 15524 | Ig-107 | 45 | rs548285460 | 0.829 | None | 0.999 | D | 0.483 | 0.707 | 0.529861178392 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 16008 | Ig-109 | 41 | rs771224957 | 0.2988 | -0.376 | 1.0 | D | 0.671 | 0.376 | 0.223146558224 | gnomAD-2.1.1 | 4.85E-05 | None | None | None | None | N | None | 0 | 1.45307E-04 | None | 0 | 1.68558E-04 | None | 0 | None | 0 | 2.69E-05 | 1.66389E-04 |
R/Q | 16008 | Ig-109 | 41 | rs771224957 | 0.2988 | -0.376 | 1.0 | D | 0.671 | 0.376 | 0.223146558224 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/Q | 16008 | Ig-109 | 41 | rs771224957 | 0.2988 | -0.376 | 1.0 | D | 0.671 | 0.376 | 0.223146558224 | gnomAD-4.0.0 | 2.4806E-05 | None | None | None | None | N | None | 4.01112E-05 | 1.33592E-04 | None | 0 | 2.23724E-05 | None | 1.5626E-05 | 0 | 2.20495E-05 | 0 | 1.60287E-05 |
R/W | 16008 | Ig-109 | 41 | rs374233884 | 0.6005 | -0.518 | 1.0 | D | 0.667 | 0.432 | 0.465891899173 | gnomAD-2.1.1 | 4.85E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 2.61472E-04 | None | 4.64E-05 | 1.79E-05 | 0 |
R/W | 16008 | Ig-109 | 41 | rs374233884 | 0.6005 | -0.518 | 1.0 | D | 0.667 | 0.432 | 0.465891899173 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
R/W | 16008 | Ig-109 | 41 | rs374233884 | 0.6005 | -0.518 | 1.0 | D | 0.667 | 0.432 | 0.465891899173 | gnomAD-4.0.0 | 2.72881E-05 | None | None | None | None | N | None | 1.33761E-05 | 0 | None | 0 | 2.23804E-05 | None | 0 | 0 | 1.61134E-05 | 2.52597E-04 | 0 |
R/I | 16304 | Ig-110 | 43 | None | 0.8662 | None | 1.0 | D | 0.717 | 0.434 | 0.567858160113 | gnomAD-4.0.0 | 2.0542E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7998E-06 | 0 | 1.65887E-05 |
R/G | 17000 | Ig-111 | 46 | rs1488377419 | 0.495 | None | 0.81 | D | 0.295 | 0.267 | 0.404453528171 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/G | 17000 | Ig-111 | 46 | rs1488377419 | 0.495 | None | 0.81 | D | 0.295 | 0.267 | 0.404453528171 | gnomAD-4.0.0 | 6.5799E-06 | None | None | None | None | N | None | 2.41278E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 17000 | Ig-111 | 46 | rs767481574 | 0.2365 | -0.399 | 0.897 | N | 0.271 | 0.195 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.81025E-04 | None | 0 | None | 0 | 0 | 0 |
R/K | 17000 | Ig-111 | 46 | rs767481574 | 0.2365 | -0.399 | 0.897 | N | 0.271 | 0.195 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.95236E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 17000 | Ig-111 | 46 | rs767481574 | 0.2365 | -0.399 | 0.897 | N | 0.271 | 0.195 | None | gnomAD-4.0.0 | 5.14654E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.83593E-03 | None | 0 | 0 | 8.48001E-07 | 0 | 0 |
R/S | 17000 | Ig-111 | 46 | None | 0.7145 | None | 0.681 | N | 0.289 | 0.175 | 0.231231049324 | gnomAD-4.0.0 | 1.5932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86202E-06 | 0 | 0 |
R/T | 17000 | Ig-111 | 46 | rs767481574 | 0.4357 | -0.499 | 0.81 | D | 0.307 | 0.451 | 0.453307948783 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
R/T | 17000 | Ig-111 | 46 | rs767481574 | 0.4357 | -0.499 | 0.81 | D | 0.307 | 0.451 | 0.453307948783 | gnomAD-4.0.0 | 2.73829E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59936E-06 | 0 | 0 |
R/C | 17321 | Ig-112 | 71 | rs752764827 | 0.8719 | -1.605 | 1.0 | N | 0.872 | 0.421 | None | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.7E-05 | 0 |
R/C | 17321 | Ig-112 | 71 | rs752764827 | 0.8719 | -1.605 | 1.0 | N | 0.872 | 0.421 | None | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
R/C | 17321 | Ig-112 | 71 | rs752764827 | 0.8719 | -1.605 | 1.0 | N | 0.872 | 0.421 | None | gnomAD-4.0.0 | 3.59848E-05 | None | None | None | None | N | None | 2.67537E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49589E-05 | 0 | 4.81093E-05 |
R/H | 17321 | Ig-112 | 71 | rs530304166 | 0.6481 | -2.067 | 1.0 | N | 0.809 | 0.384 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 1.78E-05 | 0 |
R/H | 17321 | Ig-112 | 71 | rs530304166 | 0.6481 | -2.067 | 1.0 | N | 0.809 | 0.384 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/H | 17321 | Ig-112 | 71 | rs530304166 | 0.6481 | -2.067 | 1.0 | N | 0.809 | 0.384 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
R/H | 17321 | Ig-112 | 71 | rs530304166 | 0.6481 | -2.067 | 1.0 | N | 0.809 | 0.384 | None | gnomAD-4.0.0 | 2.10923E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.24316E-05 | None | 0 | 0 | 2.71449E-05 | 1.09994E-05 | 0 |
R/S | 17321 | Ig-112 | 71 | rs752764827 | 0.9837 | -1.086 | 1.0 | N | 0.793 | 0.452 | 0.345405024496 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
R/S | 17321 | Ig-112 | 71 | rs752764827 | 0.9837 | -1.086 | 1.0 | N | 0.793 | 0.452 | 0.345405024496 | gnomAD-4.0.0 | 6.84965E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00131E-07 | 0 | 0 |
R/C | 17717 | Ig-113 | 41 | rs369001587 | 0.298 | -0.718 | 1.0 | N | 0.604 | 0.371 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 8.91E-06 | 0 |
R/C | 17717 | Ig-113 | 41 | rs369001587 | 0.298 | -0.718 | 1.0 | N | 0.604 | 0.371 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 17717 | Ig-113 | 41 | rs369001587 | 0.298 | -0.718 | 1.0 | N | 0.604 | 0.371 | None | gnomAD-4.0.0 | 7.43944E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.68765E-05 | 0 | 3.39165E-06 | 4.39242E-05 | 1.60215E-05 |
R/H | 17717 | Ig-113 | 41 | rs757018821 | 0.1691 | -1.571 | 0.997 | N | 0.406 | 0.334 | 0.262175524916 | gnomAD-2.1.1 | 5.72E-05 | None | None | None | None | N | None | 2.48242E-04 | 1.13116E-04 | None | 0 | 0 | None | 1.30719E-04 | None | 0 | 1.57E-05 | 0 |
R/H | 17717 | Ig-113 | 41 | rs757018821 | 0.1691 | -1.571 | 0.997 | N | 0.406 | 0.334 | 0.262175524916 | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 2.17402E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
R/H | 17717 | Ig-113 | 41 | rs757018821 | 0.1691 | -1.571 | 0.997 | N | 0.406 | 0.334 | 0.262175524916 | gnomAD-4.0.0 | 2.54175E-05 | None | None | None | None | N | None | 2.00476E-04 | 5.003E-05 | None | 0 | 2.23095E-05 | None | 0 | 0 | 4.23954E-06 | 1.53725E-04 | 4.806E-05 |
R/P | 17717 | Ig-113 | 41 | rs757018821 | 0.9573 | -0.22 | 0.994 | N | 0.477 | 0.383 | 0.406120066682 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.02659E-04 | None | 0 | None | 0 | 0 | 0 |
R/P | 17717 | Ig-113 | 41 | rs757018821 | 0.9573 | -0.22 | 0.994 | N | 0.477 | 0.383 | 0.406120066682 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94704E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/P | 17717 | Ig-113 | 41 | rs757018821 | 0.9573 | -0.22 | 0.994 | N | 0.477 | 0.383 | 0.406120066682 | gnomAD-4.0.0 | 1.23988E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.4619E-05 | None | 0 | 0 | 0 | 0 | 0 |
A/S | 18013 | Ig-114 | 46 | rs531242797 | 0.0741 | -0.733 | 0.005 | N | 0.142 | 0.046 | 0.15556083564 | gnomAD-2.1.1 | 1.09207E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 8.82757E-04 | None | 0 | 0 | 0 |
A/S | 18013 | Ig-114 | 46 | rs531242797 | 0.0741 | -0.733 | 0.005 | N | 0.142 | 0.046 | 0.15556083564 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 8.29531E-04 | 0 |
A/S | 18013 | Ig-114 | 46 | rs531242797 | 0.0741 | -0.733 | 0.005 | N | 0.142 | 0.046 | 0.15556083564 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
A/S | 18013 | Ig-114 | 46 | rs531242797 | 0.0741 | -0.733 | 0.005 | N | 0.142 | 0.046 | 0.15556083564 | gnomAD-4.0.0 | 4.4027E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 7.69045E-04 | 1.602E-05 |
A/T | 18013 | Ig-114 | 46 | rs531242797 | 0.0599 | -0.701 | None | N | 0.078 | 0.071 | 0.178374595973 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
A/T | 18013 | Ig-114 | 46 | rs531242797 | 0.0599 | -0.701 | None | N | 0.078 | 0.071 | 0.178374595973 | gnomAD-4.0.0 | 6.84636E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9987E-07 | 0 | 0 |
H/Y | 18737 | Ig-116 | 50 | None | 0.1854 | None | 0.999 | N | 0.581 | 0.431 | 0.278968121808 | gnomAD-4.0.0 | 1.59293E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43456E-05 | 0 |
R/C | 19432 | Ig-118 | 42 | rs1345945391 | 0.1348 | -0.037 | 0.022 | N | 0.257 | 0.275 | 0.216624796971 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.87853E-04 | 0 | 0 |
R/C | 19432 | Ig-118 | 42 | rs1345945391 | 0.1348 | -0.037 | 0.022 | N | 0.257 | 0.275 | 0.216624796971 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.43E-05 | 0 | 0 | 0 | 0 |
R/C | 19432 | Ig-118 | 42 | rs1345945391 | 0.1348 | -0.037 | 0.022 | N | 0.257 | 0.275 | 0.216624796971 | gnomAD-4.0.0 | 3.71919E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.5626E-05 | 0 | 3.39093E-06 | 0 | 1.60169E-05 |
R/H | 19432 | Ig-118 | 42 | rs745631866 | 0.0919 | -1.09 | 0.956 | N | 0.259 | 0.308 | None | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 8.71E-05 | None | 0 | 5.61E-05 | None | 9.8E-05 | None | 0 | 0 | 0 |
R/H | 19432 | Ig-118 | 42 | rs745631866 | 0.0919 | -1.09 | 0.956 | N | 0.259 | 0.308 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94099E-04 | None | 0 | 0 | 1.47E-05 | 0 | 4.78927E-04 |
R/H | 19432 | Ig-118 | 42 | rs745631866 | 0.0919 | -1.09 | 0.956 | N | 0.259 | 0.308 | None | gnomAD-4.0.0 | 1.48771E-05 | None | None | None | None | N | None | 1.33604E-05 | 8.34251E-05 | None | 0 | 1.11772E-04 | None | 0 | 0 | 5.08644E-06 | 4.39203E-05 | 4.80492E-05 |
R/I | 19832 | Ig-119 | 43 | rs1405596883 | 0.117 | None | 0.029 | N | 0.493 | 0.141 | 0.365509141856 | gnomAD-4.0.0 | 3.18366E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88253E-05 | 0 | 2.8594E-06 | 0 | 0 |
R/K | 19832 | Ig-119 | 43 | rs1405596883 | 0.075 | -0.781 | 0.005 | N | 0.16 | 0.085 | 0.112648838833 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
R/K | 19832 | Ig-119 | 43 | rs1405596883 | 0.075 | -0.781 | 0.005 | N | 0.16 | 0.085 | 0.112648838833 | gnomAD-4.0.0 | 1.59183E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8594E-06 | 0 | 0 |
R/K | 20522 | Ig-121 | 44 | rs1204056923 | 0.2767 | None | 0.863 | N | 0.381 | 0.198 | 0.27479166964 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/K | 20522 | Ig-121 | 44 | rs1204056923 | 0.2767 | None | 0.863 | N | 0.381 | 0.198 | 0.27479166964 | gnomAD-4.0.0 | 5.07532E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.02495E-06 | 0 | 0 |
R/S | 20522 | Ig-121 | 44 | rs576946726 | 0.8211 | -0.999 | 0.939 | N | 0.398 | 0.319 | 0.151104730317 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.05994E-04 | None | 0 | None | 0 | 0 | 0 |
R/S | 20522 | Ig-121 | 44 | rs576946726 | 0.8211 | -0.999 | 0.939 | N | 0.398 | 0.319 | 0.151104730317 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94175E-04 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 20522 | Ig-121 | 44 | rs576946726 | 0.8211 | -0.999 | 0.939 | N | 0.398 | 0.319 | 0.151104730317 | gnomAD-4.0.0 | 2.48004E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.93416E-05 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 20817 | Ig-122 | 49 | None | 0.3518 | None | 0.997 | N | 0.537 | 0.401 | 0.387850303812 | gnomAD-4.0.0 | 1.59198E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
R/S | 20817 | Ig-122 | 49 | rs372984487 | 0.8625 | None | 1.0 | N | 0.725 | 0.346 | 0.241078983079 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 20817 | Ig-122 | 49 | rs372984487 | 0.8625 | None | 1.0 | N | 0.725 | 0.346 | 0.241078983079 | gnomAD-4.0.0 | 6.8434E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99572E-07 | 0 | 0 |
R/W | 20817 | Ig-122 | 49 | None | 0.4618 | None | 1.0 | D | 0.721 | 0.613 | 0.603771522108 | gnomAD-4.0.0 | 4.79027E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29689E-06 | 0 | 0 |
H/L | 21512 | Ig-124 | 44 | rs774754081 | 0.2311 | 0.435 | 0.081 | N | 0.331 | 0.151 | None | gnomAD-2.1.1 | 1.79E-05 | None | None | None | None | N | None | 2.06868E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
H/L | 21512 | Ig-124 | 44 | rs774754081 | 0.2311 | 0.435 | 0.081 | N | 0.331 | 0.151 | None | gnomAD-3.1.2 | 6.57E-05 | None | None | None | None | N | None | 2.41255E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
H/L | 21512 | Ig-124 | 44 | rs774754081 | 0.2311 | 0.435 | 0.081 | N | 0.331 | 0.151 | None | gnomAD-4.0.0 | 1.17773E-05 | None | None | None | None | N | None | 2.00272E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39128E-06 | 0 | 0 |
G/C | 21909 | Ig-125 | 44 | rs878898044 | 0.3163 | -0.352 | 0.98 | N | 0.638 | 0.425 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
G/C | 21909 | Ig-125 | 44 | rs878898044 | 0.3163 | -0.352 | 0.98 | N | 0.638 | 0.425 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
G/C | 21909 | Ig-125 | 44 | rs878898044 | 0.3163 | -0.352 | 0.98 | N | 0.638 | 0.425 | None | gnomAD-4.0.0 | 1.86184E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54546E-06 | 0 | 0 |
R/G | 22596 | Ig-127 | 37 | rs761026013 | 0.8057 | -0.818 | 1.0 | N | 0.659 | 0.525 | 0.471620082127 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
R/G | 22596 | Ig-127 | 37 | rs761026013 | 0.8057 | -0.818 | 1.0 | N | 0.659 | 0.525 | 0.471620082127 | gnomAD-4.0.0 | 4.7905E-06 | None | None | None | None | N | None | 0 | 2.23634E-05 | None | 0 | 0 | None | 0 | 0 | 5.39788E-06 | 0 | 0 |
R/T | 22596 | Ig-127 | 37 | rs1197078573 | 0.8158 | -0.227 | 1.0 | N | 0.703 | 0.479 | 0.482500522706 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/T | 22596 | Ig-127 | 37 | rs1197078573 | 0.8158 | -0.227 | 1.0 | N | 0.703 | 0.479 | 0.482500522706 | gnomAD-4.0.0 | 3.18399E-06 | None | None | None | None | N | None | 0 | 4.57352E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
I/T | 22993 | Ig-128 | 44 | rs2046666627 | 0.1241 | None | 0.001 | N | 0.195 | 0.058 | 0.407767136052 | gnomAD-3.1.2 | 6.6E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.08681E-04 | 0 |
I/T | 22993 | Ig-128 | 44 | rs2046666627 | 0.1241 | None | 0.001 | N | 0.195 | 0.058 | 0.407767136052 | gnomAD-4.0.0 | 6.5977E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.08681E-04 | 0 |
I/V | 22993 | Ig-128 | 44 | rs752579029 | 0.0715 | -0.796 | 0.001 | N | 0.109 | 0.047 | 0.339555952218 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
I/V | 22993 | Ig-128 | 44 | rs752579029 | 0.0715 | -0.796 | 0.001 | N | 0.109 | 0.047 | 0.339555952218 | gnomAD-4.0.0 | 1.59204E-06 | None | None | None | None | N | None | 0 | 2.28697E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 23679 | Ig-130 | 43 | rs200144345 | 0.3616 | -0.723 | 0.997 | N | 0.466 | 0.224 | None | gnomAD-2.1.1 | 5.22477E-04 | None | None | None | None | N | None | 4.14E-05 | 2.84E-05 | None | 3.00388E-03 | 0 | None | 6.87308E-04 | None | 4.01E-05 | 6.73E-04 | 7.05617E-04 |
R/K | 23679 | Ig-130 | 43 | rs200144345 | 0.3616 | -0.723 | 0.997 | N | 0.466 | 0.224 | None | gnomAD-3.1.2 | 4.07686E-04 | None | None | None | None | N | None | 7.24E-05 | 3.92927E-04 | 0 | 2.59366E-03 | 0 | None | 0 | 3.16456E-03 | 5.73648E-04 | 6.21633E-04 | 4.78469E-04 |
R/K | 23679 | Ig-130 | 43 | rs200144345 | 0.3616 | -0.723 | 0.997 | N | 0.466 | 0.224 | None | gnomAD-4.0.0 | 5.92587E-04 | None | None | None | None | N | None | 6.66542E-05 | 1.33369E-04 | None | 2.83937E-03 | 0 | None | 6.25215E-05 | 1.32144E-03 | 6.26505E-04 | 6.91897E-04 | 7.206E-04 |
R/T | 24761 | Ig-133 | 46 | rs1708301817 | 0.9257 | None | 1.0 | N | 0.694 | 0.463 | 0.622825188919 | gnomAD-4.0.0 | 2.0529E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.82819E-05 | 0 | None | 0 | 0 | 1.79916E-06 | 0 | 0 |
R/L | 25157 | Ig-134 | 47 | None | 0.3406 | None | 0.722 | N | 0.433 | 0.305 | 0.405700215632 | gnomAD-4.0.0 | 6.84339E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99588E-07 | 0 | 0 |
R/Q | 25157 | Ig-134 | 47 | rs779410073 | 0.161 | -0.079 | 0.742 | N | 0.454 | 0.249 | 0.107399877778 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.33E-05 | 0 |
R/Q | 25157 | Ig-134 | 47 | rs779410073 | 0.161 | -0.079 | 0.742 | N | 0.454 | 0.249 | 0.107399877778 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 25157 | Ig-134 | 47 | rs779410073 | 0.161 | -0.079 | 0.742 | N | 0.454 | 0.249 | 0.107399877778 | gnomAD-4.0.0 | 8.67763E-06 | None | None | None | None | N | None | 1.33536E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.10206E-05 | 0 | 0 |
R/G | 25843 | Ig-136 | 46 | rs773999364 | 0.8917 | -1.579 | 0.892 | N | 0.475 | 0.252 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/G | 25843 | Ig-136 | 46 | rs773999364 | 0.8917 | -1.579 | 0.892 | N | 0.475 | 0.252 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/G | 25843 | Ig-136 | 46 | rs773999364 | 0.8917 | -1.579 | 0.892 | N | 0.475 | 0.252 | None | gnomAD-4.0.0 | 2.47933E-06 | None | None | None | None | N | None | 4.00598E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47777E-07 | 0 | 0 |
R/K | 25843 | Ig-136 | 46 | rs1706876007 | 0.4733 | None | 0.025 | N | 0.203 | 0.255 | 0.26169431596 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/K | 25843 | Ig-136 | 46 | rs1706876007 | 0.4733 | None | 0.025 | N | 0.203 | 0.255 | 0.26169431596 | gnomAD-4.0.0 | 1.85959E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54336E-06 | 0 | 0 |
R/S | 25843 | Ig-136 | 46 | rs2154167135 | 0.9447 | None | 0.892 | N | 0.483 | 0.256 | 0.332133492242 | gnomAD-4.0.0 | 1.59196E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4332E-05 | 0 |
R/T | 25843 | Ig-136 | 46 | None | 0.8984 | None | 0.967 | N | 0.478 | 0.434 | 0.426436156839 | gnomAD-4.0.0 | 1.16339E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52936E-05 | 0 | 0 |
R/G | 26925 | Ig-139 | 46 | rs373948797 | 0.9421 | -1.139 | 0.892 | N | 0.391 | 0.347 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
R/G | 26925 | Ig-139 | 46 | rs373948797 | 0.9421 | -1.139 | 0.892 | N | 0.391 | 0.347 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/G | 26925 | Ig-139 | 46 | rs373948797 | 0.9421 | -1.139 | 0.892 | N | 0.391 | 0.347 | None | gnomAD-4.0.0 | 6.5735E-06 | None | None | None | None | N | None | 2.41231E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 26925 | Ig-139 | 46 | rs748215561 | 0.5417 | -0.448 | 0.773 | N | 0.47 | 0.255 | 0.202949470691 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.45E-05 | 0 |
R/K | 26925 | Ig-139 | 46 | rs748215561 | 0.5417 | -0.448 | 0.773 | N | 0.47 | 0.255 | 0.202949470691 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
R/K | 26925 | Ig-139 | 46 | rs748215561 | 0.5417 | -0.448 | 0.773 | N | 0.47 | 0.255 | 0.202949470691 | gnomAD-4.0.0 | 1.79736E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.45831E-05 | 0 | 0 |
R/K | 28008 | Ig-142 | 46 | None | 0.3955 | None | 0.997 | N | 0.461 | 0.372 | 0.239305524855 | gnomAD-4.0.0 | 1.59261E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85982E-06 | 0 | 0 |
R/T | 28403 | Ig-143 | 46 | rs750869245 | 0.2732 | -0.656 | 0.001 | N | 0.264 | 0.236 | 0.42324137094 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 1.74004E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/T | 28403 | Ig-143 | 46 | rs750869245 | 0.2732 | -0.656 | 0.001 | N | 0.264 | 0.236 | 0.42324137094 | gnomAD-4.0.0 | 1.1139E-05 | None | None | None | None | N | None | 0 | 1.60066E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 29090 | Ig-145 | 46 | None | 0.5 | None | 0.997 | N | 0.473 | 0.283 | 0.379881503574 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 29090 | Ig-145 | 46 | rs1335648809 | 0.9426 | None | 1.0 | N | 0.737 | 0.428 | 0.308278614506 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/S | 29090 | Ig-145 | 46 | rs1335648809 | 0.9426 | None | 1.0 | N | 0.737 | 0.428 | 0.308278614506 | gnomAD-4.0.0 | 1.36833E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79886E-06 | 0 | 0 |
L/M | 29486 | Ig-146 | 43 | None | 0.0893 | None | 0.984 | N | 0.481 | 0.176 | 0.452264262256 | gnomAD-4.0.0 | 1.59158E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85829E-06 | 0 | 0 |
L/P | 29486 | Ig-146 | 43 | rs1376620284 | 0.4612 | -0.731 | 0.984 | N | 0.595 | 0.268 | 0.628357094819 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66279E-04 |
L/P | 29486 | Ig-146 | 43 | rs1376620284 | 0.4612 | -0.731 | 0.984 | N | 0.595 | 0.268 | 0.628357094819 | gnomAD-4.0.0 | 1.59156E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02517E-05 |
R/G | 29885 | Ig-147 | 44 | rs368173790 | 0.4257 | -1.712 | 0.645 | N | 0.497 | 0.267 | 0.350964488264 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
R/G | 29885 | Ig-147 | 44 | rs368173790 | 0.4257 | -1.712 | 0.645 | N | 0.497 | 0.267 | 0.350964488264 | gnomAD-4.0.0 | 1.59301E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85798E-06 | 0 | 0 |
F/C | 30177 | Ig-148 | 46 | rs772875882 | 0.0794 | -0.168 | 0.258 | N | 0.353 | 0.051 | 0.195762928549 | gnomAD-2.1.1 | 4.28E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.67E-05 | None | 0 | None | 0 | 0 | 0 |
F/C | 30177 | Ig-148 | 46 | rs772875882 | 0.0794 | -0.168 | 0.258 | N | 0.353 | 0.051 | 0.195762928549 | gnomAD-4.0.0 | 8.2216E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.39821E-04 | None | 0 | 0 | 0 | 0 | 0 |
F/L | 30177 | Ig-148 | 46 | rs748918212 | 0.3195 | -0.646 | None | N | 0.093 | 0.048 | 0.126345400529 | gnomAD-2.1.1 | 1.28E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.8E-05 | 0 |
F/L | 30177 | Ig-148 | 46 | rs748918212 | 0.3195 | -0.646 | None | N | 0.093 | 0.048 | 0.126345400529 | gnomAD-4.0.0 | 5.55105E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.61615E-05 | None | 3.80243E-05 | 0 | 2.72532E-06 | 0 | 0 |
R/Q | 31261 | Ig-151 | 44 | rs755974993 | 0.3105 | -0.4 | 1.0 | N | 0.667 | 0.371 | 0.246773566709 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
R/Q | 31261 | Ig-151 | 44 | rs755974993 | 0.3105 | -0.4 | 1.0 | N | 0.667 | 0.371 | 0.246773566709 | gnomAD-4.0.0 | 4.78932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39657E-06 | 1.15934E-05 | 0 |
K/E | 31661 | Ig-152 | 41 | rs1268995899 | 0.5798 | 0.295 | 0.999 | N | 0.566 | 0.372 | 0.215869574891 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
K/E | 31661 | Ig-152 | 41 | rs1268995899 | 0.5798 | 0.295 | 0.999 | N | 0.566 | 0.372 | 0.215869574891 | gnomAD-4.0.0 | 1.36841E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99476E-07 | 1.15934E-05 | 0 |
K/N | 31661 | Ig-152 | 41 | None | 0.6502 | None | 1.0 | N | 0.657 | 0.253 | 0.137902524267 | gnomAD-4.0.0 | 6.84208E-07 | None | None | None | None | N | None | 0 | 0 | None | 3.82673E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/Q | 32058 | Ig-153 | 42 | rs374063064 | 0.2908 | -0.08 | 1.0 | N | 0.733 | 0.331 | None | gnomAD-2.1.1 | 8.92E-05 | None | None | None | None | I | None | 1.24008E-04 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.5605E-04 | 1.40252E-04 |
R/Q | 32058 | Ig-153 | 42 | rs374063064 | 0.2908 | -0.08 | 1.0 | N | 0.733 | 0.331 | None | gnomAD-3.1.2 | 1.31539E-04 | None | None | None | None | I | None | 1.20744E-04 | 1.31165E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.91165E-04 | 0 | 0 |
R/Q | 32058 | Ig-153 | 42 | rs374063064 | 0.2908 | -0.08 | 1.0 | N | 0.733 | 0.331 | None | gnomAD-4.0.0 | 1.71673E-04 | None | None | None | None | I | None | 1.46925E-04 | 6.67E-05 | None | 3.37838E-05 | 6.68628E-05 | None | 0 | 0 | 2.09372E-04 | 1.09806E-05 | 1.60149E-04 |
R/W | 32058 | Ig-153 | 42 | rs201463708 | 0.5913 | -0.628 | 1.0 | D | 0.731 | 0.442 | None | gnomAD-2.1.1 | 3.21E-05 | None | None | None | None | I | None | 1.6533E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.12E-05 | 1.40252E-04 |
R/W | 32058 | Ig-153 | 42 | rs201463708 | 0.5913 | -0.628 | 1.0 | D | 0.731 | 0.442 | None | gnomAD-3.1.2 | 7.24E-05 | None | None | None | None | I | None | 1.93424E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
R/W | 32058 | Ig-153 | 42 | rs201463708 | 0.5913 | -0.628 | 1.0 | D | 0.731 | 0.442 | None | gnomAD-4.0.0 | 2.23124E-05 | None | None | None | None | I | None | 1.4702E-04 | 0 | None | 0 | 0 | None | 3.12471E-05 | 0 | 1.61057E-05 | 0 | 6.40553E-05 |
R/C | 32352 | Ig-154 | 46 | rs753874904 | 0.6432 | -1.143 | 1.0 | N | 0.749 | 0.474 | 0.69617267371 | gnomAD-2.1.1 | 3.63E-05 | None | None | None | None | N | None | 0 | 2.60854E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
R/C | 32352 | Ig-154 | 46 | rs753874904 | 0.6432 | -1.143 | 1.0 | N | 0.749 | 0.474 | 0.69617267371 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 32352 | Ig-154 | 46 | rs753874904 | 0.6432 | -1.143 | 1.0 | N | 0.749 | 0.474 | 0.69617267371 | gnomAD-4.0.0 | 2.16904E-05 | None | None | None | None | N | None | 0 | 2.33396E-04 | None | 0 | 0 | None | 0 | 0 | 1.69524E-05 | 1.09789E-05 | 0 |
R/G | 32352 | Ig-154 | 46 | rs753874904 | 0.6262 | -1.653 | 1.0 | N | 0.679 | 0.441 | 0.588775385127 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
R/G | 32352 | Ig-154 | 46 | rs753874904 | 0.6262 | -1.653 | 1.0 | N | 0.679 | 0.441 | 0.588775385127 | gnomAD-4.0.0 | 1.36843E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.03829E-05 | None | 0 | 0 | 0 | 0 | 0 |
R/H | 32352 | Ig-154 | 46 | rs575939045 | 0.2573 | -1.619 | 1.0 | N | 0.751 | 0.37 | None | gnomAD-2.1.1 | 7.51E-05 | None | None | None | None | N | None | 0 | 1.13173E-04 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.09878E-04 | 2.81057E-04 |
R/H | 32352 | Ig-154 | 46 | rs575939045 | 0.2573 | -1.619 | 1.0 | N | 0.751 | 0.37 | None | gnomAD-3.1.2 | 1.1177E-04 | None | None | None | None | N | None | 4.83E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.05852E-04 | 0 | 0 |
R/H | 32352 | Ig-154 | 46 | rs575939045 | 0.2573 | -1.619 | 1.0 | N | 0.751 | 0.37 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
R/H | 32352 | Ig-154 | 46 | rs575939045 | 0.2573 | -1.619 | 1.0 | N | 0.751 | 0.37 | None | gnomAD-4.0.0 | 1.50579E-04 | None | None | None | None | N | None | 2.6666E-05 | 4.99983E-05 | None | 0 | 0 | None | 1.5624E-05 | 0 | 1.95802E-04 | 1.09794E-05 | 8.0023E-05 |
R/L | 32352 | Ig-154 | 46 | rs575939045 | 0.6151 | None | 1.0 | N | 0.679 | 0.423 | 0.575080649919 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
R/L | 32352 | Ig-154 | 46 | rs575939045 | 0.6151 | None | 1.0 | N | 0.679 | 0.423 | 0.575080649919 | gnomAD-4.0.0 | 6.57471E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
R/S | 32352 | Ig-154 | 46 | None | 0.8525 | None | 1.0 | N | 0.707 | 0.418 | 0.385906861911 | gnomAD-4.0.0 | 6.84216E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65656E-05 |
R/C | 32748 | Ig-155 | 41 | rs72648272 | 0.3663 | -0.058 | 1.0 | N | 0.717 | 0.354 | None | gnomAD-2.1.1 | 3.97485E-03 | None | None | None | None | N | None | 2.47995E-04 | 5.09338E-04 | None | 1.16032E-03 | 0 | None | 2.74492E-03 | None | 8.83505E-03 | 5.86876E-03 | 2.94448E-03 |
R/C | 32748 | Ig-155 | 41 | rs72648272 | 0.3663 | -0.058 | 1.0 | N | 0.717 | 0.354 | None | gnomAD-3.1.2 | 3.6019E-03 | None | None | None | None | N | None | 5.06806E-04 | 1.17894E-03 | 1.09649E-03 | 1.15274E-03 | 0 | None | 1.05581E-02 | 0 | 5.55637E-03 | 2.69821E-03 | 4.78011E-04 |
R/C | 32748 | Ig-155 | 41 | rs72648272 | 0.3663 | -0.058 | 1.0 | N | 0.717 | 0.354 | None | 1000 genomes | 1.39776E-03 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 2E-03 | None | None | None | 4.1E-03 | None |
R/C | 32748 | Ig-155 | 41 | rs72648272 | 0.3663 | -0.058 | 1.0 | N | 0.717 | 0.354 | None | gnomAD-4.0.0 | 3.45949E-03 | None | None | None | None | N | None | 4.26496E-04 | 7.66616E-04 | None | 8.78319E-04 | 2.22856E-05 | None | 8.96791E-03 | 1.65017E-03 | 3.82105E-03 | 2.22901E-03 | 2.91284E-03 |
R/H | 32748 | Ig-155 | 41 | rs397517775 | 0.1694 | -0.632 | 1.0 | N | 0.706 | 0.338 | None | gnomAD-2.1.1 | 6.42E-05 | None | None | None | None | N | None | 8.26E-05 | 0 | None | 0 | 1.53815E-04 | None | 3.27E-05 | None | 0 | 9.36E-05 | 0 |
R/H | 32748 | Ig-155 | 41 | rs397517775 | 0.1694 | -0.632 | 1.0 | N | 0.706 | 0.338 | None | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 1.92827E-04 | None | 0 | 0 | 1.02896E-04 | 2.07125E-04 | 0 |
R/H | 32748 | Ig-155 | 41 | rs397517775 | 0.1694 | -0.632 | 1.0 | N | 0.706 | 0.338 | None | gnomAD-4.0.0 | 6.19649E-05 | None | None | None | None | N | None | 3.99883E-05 | 0 | None | 0 | 6.68628E-05 | None | 0 | 0 | 7.45902E-05 | 3.29374E-05 | 4.80169E-05 |
H/Q | 33641 | Ig-159 | 46 | rs1691127745 | 0.224 | None | 0.042 | N | 0.131 | 0.132 | 0.107399877778 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
H/R | 33641 | Ig-159 | 46 | rs759457802 | 0.1774 | -0.984 | 0.608 | N | 0.244 | 0.202 | 0.0954503805726 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.66908E-04 | None | 0 | None | 0 | 0 | 0 |
H/R | 33641 | Ig-159 | 46 | rs759457802 | 0.1774 | -0.984 | 0.608 | N | 0.244 | 0.202 | 0.0954503805726 | gnomAD-4.0.0 | 3.18251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.54508E-05 | None | 0 | 0 | 0 | 0 | 0 |
H/Y | 33641 | Ig-159 | 46 | rs1357251504 | 0.1491 | 0.759 | 0.024 | N | 0.109 | 0.145 | 0.167679373172 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
H/Y | 33641 | Ig-159 | 46 | rs1357251504 | 0.1491 | 0.759 | 0.024 | N | 0.109 | 0.145 | 0.167679373172 | gnomAD-4.0.0 | 1.59131E-06 | None | None | None | None | N | None | 0 | 2.28634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
K/T | 34182 | Ig-160 | 46 | rs1348175807 | 0.6517 | -0.736 | 1.0 | N | 0.695 | 0.48 | 0.326074293725 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
K/T | 34182 | Ig-160 | 46 | rs1348175807 | 0.6517 | -0.736 | 1.0 | N | 0.695 | 0.48 | 0.326074293725 | gnomAD-4.0.0 | 4.77303E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57319E-06 | 0 | 0 |
N/D | 34408 | Ig-162 | 46 | None | 0.1928 | None | 0.024 | N | 0.268 | 0.153 | 0.202086224978 | gnomAD-4.0.0 | 1.59158E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.891E-05 | 0 | 0 | 0 | 0 |
N/I | 34408 | Ig-162 | 46 | None | 0.5203 | None | 0.171 | N | 0.411 | 0.197 | 0.430579932962 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
N/K | 34408 | Ig-162 | 46 | None | 0.3128 | None | None | N | 0.124 | 0.097 | 0.137902524267 | gnomAD-4.0.0 | 1.59182E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85773E-06 | 0 | 0 |
R/C | 35174 | Ig-164 | 46 | rs778207634 | 0.1466 | -0.859 | 0.997 | D | 0.583 | 0.52 | 0.720114801303 | gnomAD-2.1.1 | 4.82E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 5.00779E-04 | None | 3.27E-05 | None | 0 | 8.86E-06 | 0 |
R/C | 35174 | Ig-164 | 46 | rs778207634 | 0.1466 | -0.859 | 0.997 | D | 0.583 | 0.52 | 0.720114801303 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.15473E-03 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
R/C | 35174 | Ig-164 | 46 | rs778207634 | 0.1466 | -0.859 | 0.997 | D | 0.583 | 0.52 | 0.720114801303 | gnomAD-4.0.0 | 4.70925E-05 | None | None | None | None | N | None | 0 | 1.6665E-05 | None | 0 | 1.31415E-03 | None | 0 | 1.64366E-04 | 8.4754E-06 | 5.48932E-05 | 0 |
R/H | 35174 | Ig-164 | 46 | rs756575734 | 0.0913 | -1.479 | 0.028 | N | 0.229 | 0.154 | None | gnomAD-2.1.1 | 2.85E-05 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 4.67E-05 | 0 |
R/H | 35174 | Ig-164 | 46 | rs756575734 | 0.0913 | -1.479 | 0.028 | N | 0.229 | 0.154 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 2.07641E-04 | 0 |
R/H | 35174 | Ig-164 | 46 | rs756575734 | 0.0913 | -1.479 | 0.028 | N | 0.229 | 0.154 | None | gnomAD-4.0.0 | 7.3738E-05 | None | None | None | None | N | None | 6.67575E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.64489E-05 | 1.09801E-05 | 1.76113E-04 |
H/N | 35331 | Ig-165 | 46 | rs753993485 | 0.2381 | -0.579 | 0.99 | N | 0.427 | 0.446 | 0.363158594168 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
H/N | 35331 | Ig-165 | 46 | rs753993485 | 0.2381 | -0.579 | 0.99 | N | 0.427 | 0.446 | 0.363158594168 | gnomAD-4.0.0 | 1.59091E-06 | None | None | None | None | N | None | 0 | 2.28645E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
H/Y | 35331 | Ig-165 | 46 | None | 0.211 | None | 0.997 | D | 0.442 | 0.404 | 0.40417439687 | gnomAD-4.0.0 | 1.59091E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
K/T | 35465 | Ig-166 | 46 | rs1408549737 | 0.235 | None | 0.999 | N | 0.713 | 0.369 | 0.272639205421 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
K/T | 35465 | Ig-166 | 46 | rs1408549737 | 0.235 | None | 0.999 | N | 0.713 | 0.369 | 0.272639205421 | gnomAD-4.0.0 | 2.59457E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.81299E-06 | 0 | 0 |
N/D | 35747 | Ig-168 | 46 | None | 0.135 | None | 0.117 | N | 0.358 | 0.094 | 0.0482279557977 | gnomAD-4.0.0 | 1.59264E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85883E-06 | 0 | 0 |
N/H | 35747 | Ig-168 | 46 | None | 0.1074 | None | None | N | 0.143 | 0.098 | 0.0401082797425 | gnomAD-4.0.0 | 1.59264E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85883E-06 | 0 | 0 |
N/S | 35747 | Ig-168 | 46 | rs903505453 | 0.0758 | None | 0.027 | N | 0.355 | 0.181 | 0.0762999501168 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
N/S | 35747 | Ig-168 | 46 | rs903505453 | 0.0758 | None | 0.027 | N | 0.355 | 0.181 | 0.0762999501168 | gnomAD-4.0.0 | 3.09948E-06 | None | None | None | None | N | None | 1.33511E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39064E-06 | 0 | 0 |
N/Y | 35747 | Ig-168 | 46 | rs1687478590 | 0.2055 | None | 0.188 | N | 0.363 | 0.054 | 0.234412748748 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
N/Y | 35747 | Ig-168 | 46 | rs1687478590 | 0.2055 | None | 0.188 | N | 0.363 | 0.054 | 0.234412748748 | gnomAD-4.0.0 | 6.57039E-06 | None | None | None | None | N | None | 2.41173E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
R/K | 35944 | Ig-169 | 48 | None | 0.3309 | None | 0.997 | N | 0.448 | 0.372 | 0.231231049324 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | -0.358(OBSL1) -0.122(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.