Structural position:
- Domain Type: Ig
- Aligned Position: 121
- Secondary Structure Element: e
- Secondary Structure Region: β-strand D
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V/L | 54 |
Ig-1 |
49 | None | 0.354 | None | 0.094 | N | 0.469 | 0.26 | 0.378322506985 | gnomAD-4.0.0 | 4.10442E-06 | None | None | None | -1.127(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39576E-06 | 0 | 0 |
| V/M | 54 |
Ig-1 |
49 | rs139517732 |
0.2615 | -0.932 | 0.662 | N | 0.517 | 0.39 | None | gnomAD-2.1.1 | 4.25E-05 | None | None | None | -1.137(TCAP) | N | None | 0 | 2.82E-05 | None | 0 | 5.52597E-04 | None | 0 | None | 0 | 0 | 0 |
| V/M | 54 |
Ig-1 |
49 | rs139517732 |
0.2615 | -0.932 | 0.662 | N | 0.517 | 0.39 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | -1.137(TCAP) | N | None | 0 | 6.54E-05 | 0 | 0 | 9.63391E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 54 |
Ig-1 |
49 | rs139517732 |
0.2615 | -0.932 | 0.662 | N | 0.517 | 0.39 | None | 1000 genomes | 5.99042E-04 | None | None | None | -1.137(TCAP) | N | None | 0 | 0 | None | None | 3E-03 | 0 | None | None | None | 0 | None |
| V/M | 54 |
Ig-1 |
49 | rs139517732 |
0.2615 | -0.932 | 0.662 | N | 0.517 | 0.39 | None |
Itoh-Satoh (2002)
Kumar (2016)
| None |
DCM
|
het | None | -1.137(TCAP) | N | Genetic analysis of JP DCM families, unknown penetrance; decreases binding of TTN to TCAP (Y2H assay); Variant prioritisation; filtering with pathogenicity/stability tools; MD analysis of binding of TTN to TCAP | None | None | None | None | None | None | None | None | None | None | None |
| V/M | 54 |
Ig-1 |
49 | rs139517732 |
0.2615 | -0.932 | 0.662 | N | 0.517 | 0.39 | None | gnomAD-4.0.0 | 3.71722E-05 | None | None | None | -1.137(TCAP) | N | None | 1.33284E-05 | 3.33178E-05 | None | 0 | 1.11458E-03 | None | 0 | 1.65017E-04 | 3.38981E-06 | 0 | 3.19969E-05 |
| F/L | 150 |
Ig-2 |
47 | None | 0.9937 | None | 0.999 | N | 0.504 | 0.544 | 0.273938319068 | gnomAD-4.0.0 | 5.47247E-06 | None | None | None | -1.434(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19435E-06 | 0 | 0 |
| F/L | 989 |
Ig-3 |
47 | rs376548316 |
0.9985 | -1.534 | 0.999 | N | 0.5 | 0.546 | 0.570056085782 | gnomAD-2.1.1 | 5.58E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.1488E-04 | 1.63452E-04 |
| F/L | 989 |
Ig-3 |
47 | rs376548316 |
0.9985 | -1.534 | 0.999 | N | 0.5 | 0.546 | 0.570056085782 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 989 |
Ig-3 |
47 | rs376548316 |
0.9985 | -1.534 | 0.999 | N | 0.5 | 0.546 | 0.570056085782 | gnomAD-4.0.0 | 6.84075E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99303E-07 | 0 | 0 |
| Y/C | 1128 |
Ig-4 |
47 | None | 0.568 | None | 1.0 | D | 0.816 | 0.756 | 0.772762111909 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85732E-06 | 0 | 0 |
| Y/H | 1128 |
Ig-4 |
47 | None | 0.4895 | None | 1.0 | N | 0.715 | 0.682 | 0.519024713989 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 1337 |
Ig-5 |
47 | None | 0.8691 | None | 0.059 | N | 0.384 | 0.411 | 0.336400405673 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| H/R | 1503 |
Ig-6 |
47 | None | 0.3763 | None | 1.0 | N | 0.653 | 0.714 | 0.468085328875 | gnomAD-4.0.0 | 2.05249E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79871E-06 | 1.15939E-05 | 0 |
| I/V | 1604 |
Ig-7 |
49 | rs1382643483 |
0.1804 | -1.584 | 0.219 | N | 0.164 | 0.185 | 0.541015953236 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 1604 |
Ig-7 |
49 | rs1382643483 |
0.1804 | -1.584 | 0.219 | N | 0.164 | 0.185 | 0.541015953236 | gnomAD-4.0.0 | 1.59075E-06 | None | None | None | None | N | None | 0 | 2.28634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 1751 |
Ig-8 |
49 | rs1234295408 |
0.7546 | None | 0.64 | N | 0.357 | 0.263 | 0.462374447365 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 1751 |
Ig-8 |
49 | rs1234295408 |
0.7546 | None | 0.64 | N | 0.357 | 0.263 | 0.462374447365 | gnomAD-4.0.0 | 6.57082E-06 | None | None | None | None | N | None | 2.41313E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 2220 |
Ig-11 |
47 | None | 0.3939 | None | 0.032 | D | 0.424 | 0.5 | 0.483082108137 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| Y/H | 2220 |
Ig-11 |
47 | rs1235706679 |
0.5105 | -1.848 | 0.99 | D | 0.671 | 0.575 | 0.527199525852 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/H | 2220 |
Ig-11 |
47 | rs1235706679 |
0.5105 | -1.848 | 0.99 | D | 0.671 | 0.575 | 0.527199525852 | gnomAD-4.0.0 | 4.10473E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49662E-06 | 1.15931E-05 | 0 |
| Y/C | 2312 |
Ig-12 |
46 | None | 0.4034 | None | 0.999 | N | 0.752 | 0.756 | 0.7168682315 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 2312 |
Ig-12 |
46 | None | 0.4442 | None | 0.046 | N | 0.351 | 0.428 | 0.335164054921 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| V/F | 2401 |
Ig-13 |
46 | rs762102248 |
0.1823 | -1.498 | 0.864 | N | 0.768 | 0.4 | 0.671487266448 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/F | 2401 |
Ig-13 |
46 | rs762102248 |
0.1823 | -1.498 | 0.864 | N | 0.768 | 0.4 | 0.671487266448 | gnomAD-4.0.0 | 3.18112E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
| V/I | 2401 |
Ig-13 |
46 | rs762102248 |
0.0772 | -0.76 | 0.006 | N | 0.244 | 0.067 | 0.344945010812 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| V/I | 2401 |
Ig-13 |
46 | rs762102248 |
0.0772 | -0.76 | 0.006 | N | 0.244 | 0.067 | 0.344945010812 | gnomAD-4.0.0 | 4.77168E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.56991E-06 | 0 | 0 |
| V/I | 2491 |
Ig-14 |
47 | rs976008348 |
0.0715 | None | 0.37 | N | 0.224 | 0.143 | 0.370051654043 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 2491 |
Ig-14 |
47 | rs976008348 |
0.0715 | None | 0.37 | N | 0.224 | 0.143 | 0.370051654043 | gnomAD-4.0.0 | 6.57315E-06 | None | None | None | None | N | None | 0 | 6.55308E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/D | 2578 |
Ig-15 |
46 | None | 0.9102 | None | 0.999 | D | 0.82 | 0.813 | 0.770770840146 | gnomAD-4.0.0 | 6.84179E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99345E-07 | 0 | 0 |
| Y/H | 2578 |
Ig-15 |
46 | rs754592016 |
0.4796 | -2.031 | 0.999 | N | 0.703 | 0.585 | 0.407632638399 | gnomAD-2.1.1 | 2.8E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.19E-05 | 0 |
| Y/H | 2578 |
Ig-15 |
46 | rs754592016 |
0.4796 | -2.031 | 0.999 | N | 0.703 | 0.585 | 0.407632638399 | gnomAD-4.0.0 | 8.21015E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.07921E-05 | 0 | 0 |
| I/M | 2665 |
Ig-16 |
45 | rs751461803 |
0.0981 | -1.074 | 0.171 | D | 0.473 | 0.207 | 0.408444019923 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.8E-06 | 0 |
| I/M | 2665 |
Ig-16 |
45 | rs751461803 |
0.0981 | -1.074 | 0.171 | D | 0.473 | 0.207 | 0.408444019923 | gnomAD-4.0.0 | 1.5906E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85656E-06 | 0 | 0 |
| Y/C | 2753 |
Ig-17 |
47 | rs2091310789 |
0.3481 | None | 1.0 | D | 0.798 | 0.585 | 0.701639087021 | gnomAD-4.0.0 | 1.5905E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85652E-06 | 0 | 0 |
| H/R | 2840 |
Ig-18 |
46 | None | 0.3581 | None | 0.784 | N | 0.477 | 0.373 | 0.253726318573 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/S | 2927 |
Ig-19 |
46 | rs2091198989 |
0.9625 | None | 1.0 | D | 0.77 | 0.683 | 0.838527088331 | gnomAD-4.0.0 | 3.18094E-06 | None | None | None | None | N | None | 0 | 4.57247E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 3103 |
Ig-21 |
46 | rs2090782630 |
0.0943 | None | None | N | 0.178 | 0.11 | 0.411001663086 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 3103 |
Ig-21 |
46 | rs2090782630 |
0.0943 | None | None | N | 0.178 | 0.11 | 0.411001663086 | gnomAD-4.0.0 | 6.57099E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46998E-05 | 0 | 0 |
| H/D | 3194 |
Ig-22 |
48 | rs1420659953 |
0.6957 | -2.253 | 0.523 | N | 0.645 | 0.329 | 0.253205268125 | gnomAD-4.0.0 | 6.84082E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| H/R | 3194 |
Ig-22 |
48 | None | 0.4943 | None | 0.523 | N | 0.649 | 0.328 | 0.332133492242 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| H/Y | 3194 |
Ig-22 |
48 | rs1420659953 |
0.1053 | None | 0.001 | N | 0.175 | 0.103 | 0.139678290688 | gnomAD-4.0.0 | 1.36816E-06 | None | None | None | None | N | None | 5.97407E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/W | 3285 |
Ig-23 |
47 | None | 0.855 | None | 0.997 | N | 0.672 | 0.539 | 0.656562442728 | gnomAD-4.0.0 | 6.84071E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| V/A | 3511 |
Ig-25 |
47 | None | 0.2535 | None | None | None | None | 0.233 | None | gnomAD-4.0.0 | 1.59114E-06 | None | None | None | None | I | None | 5.65291E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 3706 |
Ig-26 |
47 | rs748468365 |
0.7251 | -1.589 | None | None | None | 0.124 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 1.93723E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/P | 3706 |
Ig-26 |
47 | rs748468365 |
0.7251 | -1.589 | None | None | None | 0.124 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 3706 |
Ig-26 |
47 | rs748468365 |
0.7251 | -1.589 | None | None | None | 0.124 | None | gnomAD-4.0.0 | 6.19671E-06 | None | None | None | None | N | None | 1.06778E-04 | 0 | None | 0 | 0 | None | 1.56216E-05 | 0 | 0 | 0 | 1.60097E-05 |
| Y/H | 3866 |
Ig-27 |
47 | rs777421661 |
0.2866 | -1.949 | 0.002 | N | 0.296 | 0.175 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11458E-04 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 3866 |
Ig-27 |
47 | rs777421661 |
0.2866 | -1.949 | 0.002 | N | 0.296 | 0.175 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92604E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 3866 |
Ig-27 |
47 | rs777421661 |
0.2866 | -1.949 | 0.002 | N | 0.296 | 0.175 | None | gnomAD-4.0.0 | 1.85889E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.68717E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/F | 3984 |
Ig-28 |
47 | rs776443623 |
0.1996 | -0.505 | None | N | 0.187 | 0.131 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Y/F | 3984 |
Ig-28 |
47 | rs776443623 |
0.1996 | -0.505 | None | N | 0.187 | 0.131 | None | gnomAD-4.0.0 | 1.59114E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85789E-06 | 0 | 0 |
| Y/H | 3984 |
Ig-28 |
47 | rs1263949163 |
0.222 | -1.667 | None | N | 0.285 | 0.122 | None | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.41849E-04 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 3984 |
Ig-28 |
47 | rs1263949163 |
0.222 | -1.667 | None | N | 0.285 | 0.122 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92456E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 3984 |
Ig-28 |
47 | rs1263949163 |
0.222 | -1.667 | None | N | 0.285 | 0.122 | None | gnomAD-4.0.0 | 2.56182E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.42389E-05 | None | 0 | 0 | 0 | 1.33998E-05 | 0 |
| F/L | 4650 |
Ig-29 |
45 | rs2082065436 |
0.9101 | None | 0.9 | D | 0.494 | 0.424 | None | gnomAD-4.0.0 | 1.59378E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86359E-06 | 0 | 0 |
| W/R | 4841 |
Ig-31 |
47 | rs2081362230 |
0.0526 | None | None | N | 0.363 | 0.24 | 0.0762999501168 | gnomAD-4.0.0 | 1.36836E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79889E-06 | 0 | 0 |
| Y/C | 4934 |
Ig-32 |
47 | None | 0.082 | None | None | N | 0.321 | 0.396 | 0.434384183301 | gnomAD-4.0.0 | 2.05274E-06 | None | None | None | None | N | None | 2.98739E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79892E-06 | 0 | 0 |
| Y/D | 4934 |
Ig-32 |
47 | rs2081313340 |
0.4212 | None | 0.317 | D | 0.593 | 0.448 | 0.651643192601 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/D | 4934 |
Ig-32 |
47 | rs2081313340 |
0.4212 | None | 0.317 | D | 0.593 | 0.448 | 0.651643192601 | gnomAD-4.0.0 | 6.57134E-06 | None | None | None | None | N | None | 2.41231E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 4934 |
Ig-32 |
47 | None | 0.1402 | None | None | N | 0.287 | 0.23 | 0.273938319068 | gnomAD-4.0.0 | 1.59148E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85819E-06 | 0 | 0 |
| Y/H | 5121 |
Ig-34 |
47 | rs2081084380 |
0.6524 | None | 1.0 | N | 0.727 | 0.461 | 0.508696012846 | gnomAD-4.0.0 | 3.18298E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71729E-06 | 0 | 0 |
| I/V | 5214 |
Ig-35 |
47 | None | 0.0722 | None | 0.001 | N | 0.195 | 0.078 | 0.386721274199 | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88232E-05 | 0 | 0 | 0 | 0 |
| Y/D | 5307 |
Ig-36 |
47 | rs1349650603 |
0.8652 | -3.215 | 0.901 | D | 0.699 | 0.594 | 0.738898308675 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| Y/D | 5307 |
Ig-36 |
47 | rs1349650603 |
0.8652 | -3.215 | 0.901 | D | 0.699 | 0.594 | 0.738898308675 | gnomAD-4.0.0 | 1.59123E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8582E-06 | 0 | 0 |
| Y/F | 5403 |
Ig-37 |
47 | None | 0.1262 | None | 0.003 | N | 0.175 | 0.231 | 0.333154297509 | gnomAD-4.0.0 | 1.59173E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| C/Y | 5496 |
Ig-38 |
47 | rs373848201 |
0.2443 | -1.371 | 0.116 | N | 0.439 | 0.279 | None | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 1.29316E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 5496 |
Ig-38 |
47 | rs373848201 |
0.2443 | -1.371 | 0.116 | N | 0.439 | 0.279 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 5496 |
Ig-38 |
47 | rs373848201 |
0.2443 | -1.371 | 0.116 | N | 0.439 | 0.279 | None | gnomAD-4.0.0 | 2.56283E-06 | None | None | None | None | N | None | 3.38375E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 5683 |
Ig-40 |
47 | rs72648942 |
0.231 | -1.57 | 0.035 | N | 0.449 | 0.421 | None | gnomAD-2.1.1 | 5.44899E-03 | None | None | None | None | N | None | 1.36431E-03 | 1.75339E-03 | None | 1.02574E-02 | 1.0247E-04 | None | 5.58824E-03 | None | 3.67647E-03 | 7.97448E-03 | 5.61798E-03 |
| Y/C | 5683 |
Ig-40 |
47 | rs72648942 |
0.231 | -1.57 | 0.035 | N | 0.449 | 0.421 | None | gnomAD-3.1.2 | 4.69132E-03 | None | None | None | None | N | None | 1.30265E-03 | 3.27397E-03 | 0 | 8.06916E-03 | 1.9253E-04 | None | 4.98871E-03 | 3.16456E-03 | 7.46707E-03 | 3.51676E-03 | 9.57854E-04 |
| Y/C | 5683 |
Ig-40 |
47 | rs72648942 |
0.231 | -1.57 | 0.035 | N | 0.449 | 0.421 | None | 1000 genomes | 1.99681E-03 | None | None | None | None | N | None | 8E-04 | 7.2E-03 | None | None | 0 | 2E-03 | None | None | None | 2E-03 | None |
| Y/C | 5683 |
Ig-40 |
47 | rs72648942 |
0.231 | -1.57 | 0.035 | N | 0.449 | 0.421 | None | gnomAD-4.0.0 | 6.7162E-03 | None | None | None | None | N | None | 1.29254E-03 | 2.39952E-03 | None | 9.42631E-03 | 6.68539E-05 | None | 4.13894E-03 | 2.80436E-03 | 7.72101E-03 | 6.23573E-03 | 5.71456E-03 |
| Y/D | 5683 |
Ig-40 |
47 | rs371062603 |
0.8445 | -3.134 | 0.884 | D | 0.643 | 0.56 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/D | 5683 |
Ig-40 |
47 | rs371062603 |
0.8445 | -3.134 | 0.884 | D | 0.643 | 0.56 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/D | 5683 |
Ig-40 |
47 | rs371062603 |
0.8445 | -3.134 | 0.884 | D | 0.643 | 0.56 | None | gnomAD-4.0.0 | 1.31451E-05 | None | None | None | None | N | None | 4.82765E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 5776 |
Ig-41 |
47 | rs928844023 |
0.1078 | None | 0.655 | D | 0.593 | 0.146 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/M | 5776 |
Ig-41 |
47 | rs928844023 |
0.1078 | None | 0.655 | D | 0.593 | 0.146 | None | gnomAD-4.0.0 | 3.84352E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.17879E-06 | 0 | 0 |
| I/T | 5776 |
Ig-41 |
47 | None | 0.1377 | None | 0.007 | N | 0.367 | 0.275 | 0.642082960585 | gnomAD-4.0.0 | 1.36843E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79893E-06 | 0 | 0 |
| I/V | 5776 |
Ig-41 |
47 | rs767553328 |
0.0719 | -1.541 | 0.001 | N | 0.121 | 0.117 | 0.401612077098 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.88E-06 | 0 |
| I/V | 5776 |
Ig-41 |
47 | rs767553328 |
0.0719 | -1.541 | 0.001 | N | 0.121 | 0.117 | 0.401612077098 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.9305E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 5776 |
Ig-41 |
47 | rs767553328 |
0.0719 | -1.541 | 0.001 | N | 0.121 | 0.117 | 0.401612077098 | gnomAD-4.0.0 | 4.95763E-06 | None | None | None | None | N | None | 1.33518E-05 | 0 | None | 0 | 2.22886E-05 | None | 0 | 0 | 2.54282E-06 | 2.19578E-05 | 1.60138E-05 |
| Y/H | 5965 |
Ig-43 |
47 | rs752226947 |
0.2635 | -1.383 | None | N | 0.131 | 0.117 | 0.26547132957 | gnomAD-2.1.1 | 5.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.09728E-04 | 0 |
| Y/H | 5965 |
Ig-43 |
47 | rs752226947 |
0.2635 | -1.383 | None | N | 0.131 | 0.117 | 0.26547132957 | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.32341E-04 | 0 | 0 |
| Y/H | 5965 |
Ig-43 |
47 | rs752226947 |
0.2635 | -1.383 | None | N | 0.131 | 0.117 | 0.26547132957 | gnomAD-4.0.0 | 2.60307E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.13644E-05 | 0 | 8.00743E-05 |
| R/C | 6058 |
Ig-44 |
47 | rs189127014 |
0.1121 | -1.729 | 0.079 | N | 0.367 | 0.273 | None | gnomAD-2.1.1 | 1.71635E-04 | None | None | None | None | N | None | 1.48908E-03 | 1.41812E-04 | None | 0 | 1.54512E-04 | None | 3.27E-05 | None | 0 | 2.35E-05 | 0 |
| R/C | 6058 |
Ig-44 |
47 | rs189127014 |
0.1121 | -1.729 | 0.079 | N | 0.367 | 0.273 | None | gnomAD-3.1.2 | 4.73653E-04 | None | None | None | None | N | None | 1.4978E-03 | 3.93546E-04 | 0 | 0 | 1.93498E-04 | None | 0 | 0 | 0 | 2.07727E-04 | 9.56023E-04 |
| R/C | 6058 |
Ig-44 |
47 | rs189127014 |
0.1121 | -1.729 | 0.079 | N | 0.367 | 0.273 | None | gnomAD-4.0.0 | 9.91744E-05 | None | None | None | None | N | None | 1.57384E-03 | 2.50292E-04 | None | 0 | 8.93296E-05 | None | 0 | 1.65071E-04 | 5.08639E-06 | 3.29533E-05 | 2.08167E-04 |
| R/H | 6058 |
Ig-44 |
47 | rs376012117 |
0.1114 | -2.305 | 0.169 | N | 0.262 | 0.193 | 0.21737058555 | gnomAD-2.1.1 | 6.08E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.15E-05 | None | 0 | None | 5.20208E-04 | 2.35E-05 | 0 |
| R/H | 6058 |
Ig-44 |
47 | rs376012117 |
0.1114 | -2.305 | 0.169 | N | 0.262 | 0.193 | 0.21737058555 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 3.77216E-04 | 0 | 1.47E-05 | 0 | 0 |
| R/H | 6058 |
Ig-44 |
47 | rs376012117 |
0.1114 | -2.305 | 0.169 | N | 0.262 | 0.193 | 0.21737058555 | gnomAD-4.0.0 | 3.59504E-05 | None | None | None | None | N | None | 1.33337E-05 | 1.66828E-05 | None | 0 | 4.46588E-05 | None | 4.84587E-04 | 0 | 1.61071E-05 | 1.09842E-05 | 4.80415E-05 |
| R/L | 6058 |
Ig-44 |
47 | rs376012117 |
0.1836 | -0.754 | 0.967 | N | 0.541 | 0.301 | 0.602001837285 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.9E-06 | 0 |
| R/L | 6058 |
Ig-44 |
47 | rs376012117 |
0.1836 | -0.754 | 0.967 | N | 0.541 | 0.301 | 0.602001837285 | gnomAD-4.0.0 | 2.05315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79918E-06 | 1.15988E-05 | 0 |
| H/L | 6152 |
Ig-45 |
48 | rs2080071193 |
0.106 | None | 0.062 | N | 0.573 | 0.251 | 0.482209950775 | gnomAD-4.0.0 | 3.18298E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.54877E-05 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 6152 |
Ig-45 |
48 | None | 0.0927 | None | 0.117 | N | 0.553 | 0.28 | 0.270889551736 | gnomAD-4.0.0 | 1.59149E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| C/F | 6620 |
Ig-50 |
47 | None | 0.2311 | None | 0.565 | N | 0.7 | 0.295 | 0.774720988625 | gnomAD-4.0.0 | 6.84404E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99711E-07 | 0 | 0 |
| C/R | 6620 |
Ig-50 |
47 | rs1470771648 |
0.6738 | None | 0.949 | N | 0.801 | 0.581 | 0.841100326879 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 6620 |
Ig-50 |
47 | rs1470771648 |
0.6738 | None | 0.949 | N | 0.801 | 0.581 | 0.841100326879 | gnomAD-4.0.0 | 6.5735E-06 | None | None | None | None | N | None | 2.41289E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 6620 |
Ig-50 |
47 | rs935626596 |
0.215 | -1.366 | 0.003 | N | 0.453 | 0.285 | 0.592799456133 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.66945E-04 | None | 0 | None | 0 | 8.88E-06 | 0 |
| C/Y | 6620 |
Ig-50 |
47 | rs935626596 |
0.215 | -1.366 | 0.003 | N | 0.453 | 0.285 | 0.592799456133 | gnomAD-4.0.0 | 6.15963E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52016E-05 | None | 0 | 0 | 5.39827E-06 | 2.31954E-05 | 0 |
| Y/C | 6714 |
Ig-51 |
48 | rs774722320 |
0.1997 | -1.631 | 0.003 | N | 0.423 | 0.44 | 0.493695379898 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Y/C | 6714 |
Ig-51 |
48 | rs774722320 |
0.1997 | -1.631 | 0.003 | N | 0.423 | 0.44 | 0.493695379898 | gnomAD-4.0.0 | 2.05329E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6991E-06 | 0 | 0 |
| Y/H | 6807 |
Ig-52 |
47 | None | 0.6192 | None | 0.535 | D | 0.37 | 0.261 | 0.39694197178 | gnomAD-4.0.0 | 1.36897E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79943E-06 | 0 | 0 |
| I/M | 6901 |
Ig-53 |
48 | rs1402912841 |
0.0945 | None | 0.427 | N | 0.601 | 0.302 | 0.480497669815 | gnomAD-4.0.0 | 6.8441E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16015E-05 | 0 |
| I/T | 6901 |
Ig-53 |
48 | rs770055282 |
0.0947 | -2.714 | None | N | 0.306 | 0.395 | 0.573784085325 | gnomAD-2.1.1 | 5.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.92542E-04 | None | 0 | 0 | 1.65893E-04 |
| I/T | 6901 |
Ig-53 |
48 | rs770055282 |
0.0947 | -2.714 | None | N | 0.306 | 0.395 | 0.573784085325 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| I/T | 6901 |
Ig-53 |
48 | rs770055282 |
0.0947 | -2.714 | None | N | 0.306 | 0.395 | 0.573784085325 | gnomAD-4.0.0 | 2.6034E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.64528E-04 | 8.47785E-07 | 4.06424E-04 | 4.8043E-05 |
| I/V | 6901 |
Ig-53 |
48 | None | 0.0748 | None | None | N | 0.169 | 0.139 | 0.559541123154 | gnomAD-4.0.0 | 1.59219E-06 | None | None | None | None | N | None | 0 | 2.28749E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 7090 |
Ig-55 |
47 | rs1560711168 |
0.2081 | None | 0.999 | N | 0.697 | 0.561 | 0.754557078919 | gnomAD-4.0.0 | 1.59189E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| Y/N | 7090 |
Ig-55 |
47 | None | 0.2865 | None | 0.896 | D | 0.573 | 0.534 | 0.76754552583 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/G | 7183 |
Ig-56 |
47 | None | 0.2757 | None | 0.98 | N | 0.688 | 0.502 | 0.802337023659 | gnomAD-4.0.0 | 1.59216E-06 | None | None | None | None | N | None | 5.66123E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 7183 |
Ig-56 |
47 | rs1295622488 |
0.5768 | -1.253 | 0.997 | N | 0.755 | 0.562 | 0.744421343069 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/R | 7183 |
Ig-56 |
47 | rs1295622488 |
0.5768 | -1.253 | 0.997 | N | 0.755 | 0.562 | 0.744421343069 | gnomAD-4.0.0 | 3.18433E-06 | None | None | None | None | N | None | 0 | 4.57687E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 7183 |
Ig-56 |
47 | rs189951108 |
0.278 | -1.528 | 0.999 | N | 0.699 | 0.335 | None | gnomAD-2.1.1 | 3.86076E-04 | None | None | None | None | N | None | 1.65481E-04 | 4.82242E-04 | None | 0 | 0 | None | 1.96412E-04 | None | 4E-05 | 6.02052E-04 | 4.22654E-04 |
| C/Y | 7183 |
Ig-56 |
47 | rs189951108 |
0.278 | -1.528 | 0.999 | N | 0.699 | 0.335 | None | gnomAD-3.1.2 | 4.73342E-04 | None | None | None | None | N | None | 1.20668E-04 | 3.93236E-04 | 0 | 0 | 0 | None | 0 | 0 | 8.82405E-04 | 0 | 4.77555E-04 |
| C/Y | 7183 |
Ig-56 |
47 | rs189951108 |
0.278 | -1.528 | 0.999 | N | 0.699 | 0.335 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 4E-03 | None | None | None | 0 | None |
| C/Y | 7183 |
Ig-56 |
47 | rs189951108 |
0.278 | -1.528 | 0.999 | N | 0.699 | 0.335 | None | gnomAD-4.0.0 | 7.21462E-04 | None | None | None | None | N | None | 1.06655E-04 | 5.50367E-04 | None | 0 | 0 | None | 0 | 0 | 9.03708E-04 | 3.51486E-04 | 4.00333E-04 |
| C/G | 7276 |
Ig-57 |
47 | None | 0.351 | None | 0.491 | N | 0.583 | 0.381 | 0.649436034143 | gnomAD-4.0.0 | 6.84332E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52118E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 7276 |
Ig-57 |
47 | rs1362677027 |
0.4489 | None | 0.285 | N | 0.514 | 0.289 | 0.651006993216 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/S | 7276 |
Ig-57 |
47 | rs1362677027 |
0.4489 | None | 0.285 | N | 0.514 | 0.289 | 0.651006993216 | gnomAD-4.0.0 | 2.47934E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39091E-06 | 0 | 0 |
| C/Y | 7276 |
Ig-57 |
47 | None | 0.2379 | None | 0.005 | N | 0.371 | 0.29 | 0.503186968135 | gnomAD-4.0.0 | 5.47471E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19656E-06 | 0 | 0 |
| Y/C | 7561 |
Ig-60 |
47 | rs786205544 |
0.5628 | None | 1.0 | N | 0.792 | 0.505 | 0.754199488981 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 7561 |
Ig-60 |
47 | rs786205544 |
0.5628 | None | 1.0 | N | 0.792 | 0.505 | 0.754199488981 | gnomAD-4.0.0 | 2.47909E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54315E-06 | 0 | 1.60143E-05 |
| Y/H | 7561 |
Ig-60 |
47 | None | 0.7279 | None | 0.999 | N | 0.711 | 0.472 | 0.598713980857 | gnomAD-4.0.0 | 1.71075E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.24897E-05 | 0 | 0 |
| Y/F | 7655 |
Ig-61 |
48 | rs775036090 |
0.1452 | -1.06 | 0.801 | N | 0.51 | 0.206 | 0.505765104075 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/F | 7655 |
Ig-61 |
48 | rs775036090 |
0.1452 | -1.06 | 0.801 | N | 0.51 | 0.206 | 0.505765104075 | gnomAD-4.0.0 | 1.59245E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86118E-06 | 0 | 0 |
| Y/N | 7655 |
Ig-61 |
48 | None | 0.3706 | None | 0.934 | N | 0.559 | 0.553 | 0.701728203507 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| H/Y | 7935 |
Ig-64 |
47 | None | 0.0648 | None | 0.002 | N | 0.178 | 0.186 | 0.233150807113 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 8031 |
Ig-65 |
47 | rs2077976693 |
0.0594 | None | None | N | 0.34 | 0.234 | 0.414798848334 | gnomAD-4.0.0 | 1.3684E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51902E-05 | None | 0 | 0 | 8.9948E-07 | 0 | 0 |
| C/R | 8124 |
Ig-66 |
47 | rs1577966478 |
0.3004 | None | 0.999 | N | 0.735 | 0.604 | 0.854177468779 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 0 | 0 | 0 |
| C/Y | 8124 |
Ig-66 |
47 | rs754319631 |
0.251 | -1.527 | 0.4 | N | 0.429 | 0.317 | 0.651574910104 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| C/Y | 8124 |
Ig-66 |
47 | rs754319631 |
0.251 | -1.527 | 0.4 | N | 0.429 | 0.317 | 0.651574910104 | gnomAD-4.0.0 | 7.52636E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.89431E-06 | 0 | 0 |
| C/R | 8217 |
Ig-67 |
47 | None | 0.5901 | None | 0.016 | N | 0.485 | 0.382 | 0.719995979321 | gnomAD-4.0.0 | 1.59134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85842E-06 | 0 | 0 |
| Y/C | 8310 |
Ig-68 |
47 | rs879064808 |
0.1078 | -1.504 | 0.27 | N | 0.421 | 0.371 | 0.507987536778 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Y/C | 8310 |
Ig-68 |
47 | rs879064808 |
0.1078 | -1.504 | 0.27 | N | 0.421 | 0.371 | 0.507987536778 | gnomAD-4.0.0 | 3.42137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79903E-06 | 3.4781E-05 | 0 |
| Y/H | 8310 |
Ig-68 |
47 | None | 0.3683 | None | 0.046 | D | 0.313 | 0.319 | 0.370608029945 | gnomAD-4.0.0 | 6.84287E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99525E-07 | 0 | 0 |
| Y/N | 8310 |
Ig-68 |
47 | rs397517511 |
0.4197 | -2.546 | 0.987 | N | 0.628 | 0.513 | 0.837140343473 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.66963E-04 | None | 0 | None | 0 | 0 | 0 |
| Y/N | 8310 |
Ig-68 |
47 | rs397517511 |
0.4197 | -2.546 | 0.987 | N | 0.628 | 0.513 | 0.837140343473 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.85505E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 8310 |
Ig-68 |
47 | rs397517511 |
0.4197 | -2.546 | 0.987 | N | 0.628 | 0.513 | 0.837140343473 | gnomAD-4.0.0 | 4.33831E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11403E-04 | None | 0 | 0 | 0 | 0 | 3.20236E-05 |
| L/M | 8406 |
Ig-69 |
47 | rs1183682062 |
0.1059 | -1.009 | 0.01 | N | 0.237 | 0.091 | 0.302793454619 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| L/M | 8406 |
Ig-69 |
47 | rs1183682062 |
0.1059 | -1.009 | 0.01 | N | 0.237 | 0.091 | 0.302793454619 | gnomAD-4.0.0 | 1.5921E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85959E-06 | 0 | 0 |
| Y/C | 8689 |
Ig-72 |
47 | None | 0.3987 | None | 1.0 | D | 0.755 | 0.578 | 0.762425462539 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/K | 8783 |
Ig-73 |
48 | rs1226202295 |
0.3093 | None | 0.001 | N | 0.623 | 0.395 | 0.774775221225 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/K | 8783 |
Ig-73 |
48 | rs1226202295 |
0.3093 | None | 0.001 | N | 0.623 | 0.395 | 0.774775221225 | gnomAD-4.0.0 | 6.57082E-06 | None | None | None | None | N | None | 2.41231E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 8783 |
Ig-73 |
48 | None | 0.0971 | None | None | D | 0.165 | 0.075 | 0.301789629655 | gnomAD-4.0.0 | 6.84237E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99501E-07 | 0 | 0 |
| I/M | 8783 |
Ig-73 |
48 | rs767996372 |
0.0964 | -0.883 | 0.039 | N | 0.612 | 0.23 | 0.429552544315 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| I/M | 8783 |
Ig-73 |
48 | rs767996372 |
0.0964 | -0.883 | 0.039 | N | 0.612 | 0.23 | 0.429552544315 | gnomAD-4.0.0 | 6.15819E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19602E-06 | 0 | 1.65662E-05 |
| I/T | 8783 |
Ig-73 |
48 | rs1226202295 |
0.1427 | -2.256 | 0.014 | N | 0.586 | 0.252 | 0.646043907412 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| I/T | 8783 |
Ig-73 |
48 | rs1226202295 |
0.1427 | -2.256 | 0.014 | N | 0.586 | 0.252 | 0.646043907412 | gnomAD-4.0.0 | 1.36848E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51915E-05 | None | 0 | 0 | 8.99497E-07 | 0 | 0 |
| I/V | 8783 |
Ig-73 |
48 | rs2077150875 |
0.073 | None | None | N | 0.187 | 0.118 | 0.36076525451 | gnomAD-4.0.0 | 4.78966E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.598E-06 | 2.31873E-05 | 1.65673E-05 |
| Y/C | 8876 |
Ig-74 |
47 | rs1307074594 |
0.2152 | -1.904 | 1.0 | N | 0.747 | 0.524 | 0.643332317526 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| Y/C | 8972 |
Ig-75 |
47 | None | 0.3555 | None | 1.0 | N | 0.749 | 0.484 | 0.727831686896 | gnomAD-4.0.0 | 3.18357E-06 | None | None | None | None | N | None | 0 | 4.57708E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 8972 |
Ig-75 |
47 | None | 0.4442 | None | 0.265 | N | 0.394 | 0.305 | 0.353125101423 | gnomAD-4.0.0 | 1.59181E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85884E-06 | 0 | 0 |
| C/G | 9065 |
Ig-76 |
47 | rs201229221 |
0.297 | -2.414 | 0.035 | D | 0.445 | 0.386 | 0.751370582459 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| C/R | 9065 |
Ig-76 |
47 | rs201229221 |
0.5217 | -1.327 | 0.988 | D | 0.724 | 0.57 | None | gnomAD-2.1.1 | 4.29E-05 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.82E-05 | 0 |
| C/R | 9065 |
Ig-76 |
47 | rs201229221 |
0.5217 | -1.327 | 0.988 | D | 0.724 | 0.57 | None | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.17609E-04 | 0 | 0 |
| C/R | 9065 |
Ig-76 |
47 | rs201229221 |
0.5217 | -1.327 | 0.988 | D | 0.724 | 0.57 | None | gnomAD-4.0.0 | 1.62979E-04 | None | None | None | None | N | None | 6.67307E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.02578E-04 | 0 | 3.04214E-04 |
| C/S | 9065 |
Ig-76 |
47 | None | 0.4157 | None | 0.31 | N | 0.445 | 0.369 | 0.603850281814 | gnomAD-4.0.0 | 6.8422E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52016E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 9158 |
Ig-77 |
47 | None | 0.437 | None | 0.784 | D | 0.583 | 0.281 | 0.745366178539 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85798E-06 | 0 | 0 |
| C/Y | 9158 |
Ig-77 |
47 | None | 0.2606 | None | 0.01 | N | 0.433 | 0.221 | 0.633466640759 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| Y/C | 9251 |
Ig-78 |
47 | rs2076738638 |
0.055 | None | None | N | 0.201 | 0.174 | 0.382592752248 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.78927E-04 |
| Y/C | 9251 |
Ig-78 |
47 | rs2076738638 |
0.055 | None | None | N | 0.201 | 0.174 | 0.382592752248 | gnomAD-4.0.0 | 3.0447E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.2049E-06 | 0 | 6.80596E-05 |
| V/A | 9347 |
Ig-79 |
47 | None | 0.2539 | None | 0.012 | None | 0.491 | 0.196 | 0.438383285633 | gnomAD-4.0.0 | 1.5911E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76644E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 9347 |
Ig-79 |
47 | rs1382932532 |
0.1234 | -0.298 | 0.004 | None | 0.37 | 0.075 | 0.18995819373 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| V/L | 9347 |
Ig-79 |
47 | rs1382932532 |
0.1234 | -0.298 | 0.004 | None | 0.37 | 0.075 | 0.18995819373 | gnomAD-4.0.0 | 1.59109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85812E-06 | 0 | 0 |
| C/W | 9540 |
Ig-81 |
48 | None | 0.405 | None | 0.927 | None | 0.597 | 0.418 | 0.730682531328 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 9540 |
Ig-81 |
48 | rs1427971848 |
0.1767 | None | 0.001 | None | 0.415 | 0.23 | 0.475034548194 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| C/R | 9636 |
Ig-82 |
47 | rs2076080616 |
0.708 | None | 0.988 | None | 0.687 | 0.429 | 0.772638994673 | gnomAD-4.0.0 | 1.36836E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.82702E-05 | 0 | None | 0 | 0 | 0 | 0 | 1.65645E-05 |
| C/Y | 9636 |
Ig-82 |
47 | rs1434739895 |
0.3502 | -1.558 | 0.134 | None | 0.462 | 0.267 | 0.462111473445 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| C/Y | 9636 |
Ig-82 |
47 | rs1434739895 |
0.3502 | -1.558 | 0.134 | None | 0.462 | 0.267 | 0.462111473445 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 9636 |
Ig-82 |
47 | rs1434739895 |
0.3502 | -1.558 | 0.134 | None | 0.462 | 0.267 | 0.462111473445 | gnomAD-4.0.0 | 6.57013E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46981E-05 | 0 | 0 |
| V/I | 9745 |
Ig-83 |
48 | rs879159098 |
0.0579 | None | None | None | 0.147 | 0.14 | 0.167679373172 | gnomAD-4.0.0 | 1.36833E-06 | None | None | None | None | N | None | 0 | 2.23604E-05 | None | 0 | 0 | None | 0 | 0 | 8.99426E-07 | 0 | 0 |
| F/C | 9947 |
Ig-84 |
48 | None | 0.6937 | None | 0.915 | None | 0.551 | 0.416 | 0.608671624233 | gnomAD-4.0.0 | 6.8478E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51965E-05 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 9947 |
Ig-84 |
48 | None | 0.8785 | None | 0.117 | None | 0.533 | 0.392 | 0.509109621728 | gnomAD-4.0.0 | 6.8478E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00017E-07 | 0 | 0 |
| H/D | 10034 |
Ig-85 |
46 | None | 0.7212 | None | 0.007 | None | 0.453 | 0.216 | 0.0716867268079 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| Y/C | 10123 |
Ig-86 |
46 | None | 0.9523 | None | 1.0 | None | 0.839 | 0.757 | 0.77875509527 | gnomAD-4.0.0 | 1.59086E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| H/N | 13732 |
Ig-87 |
49 | None | 0.5187 | None | 0.999 | N | 0.476 | 0.407 | 0.340032825777 | gnomAD-4.0.0 | 1.5919E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88274E-05 | 0 | 0 | 0 | 0 |
| I/N | 13826 |
Ig-88 |
47 | rs1252440805 |
0.6295 | None | 0.772 | N | 0.741 | 0.138 | 0.389439708392 | gnomAD-4.0.0 | 6.84415E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9964E-07 | 0 | 0 |
| I/T | 13826 |
Ig-88 |
47 | rs1252440805 |
0.3334 | -3.055 | 0.003 | N | 0.427 | 0.149 | 0.354396617058 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 9.29E-05 | 0 | 0 |
| I/V | 13826 |
Ig-88 |
47 | None | 0.091 | None | 0.001 | N | 0.171 | 0.082 | 0.170165803431 | gnomAD-4.0.0 | 1.59242E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86005E-06 | 0 | 0 |
| T/A | 13921 |
Ig-89 |
46 | None | 0.2779 | None | 0.817 | N | 0.474 | 0.152 | 0.101711395817 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 13921 |
Ig-89 |
46 | None | 0.3099 | None | 0.126 | N | 0.398 | 0.189 | 0.186928172975 | gnomAD-4.0.0 | 6.93129E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.08001E-07 | 0 | 0 |
| F/C | 14098 |
Ig-91 |
45 | rs761607459 |
0.4693 | -2.355 | 0.999 | N | 0.547 | 0.55 | 0.791778486281 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| F/C | 14098 |
Ig-91 |
45 | rs761607459 |
0.4693 | -2.355 | 0.999 | N | 0.547 | 0.55 | 0.791778486281 | gnomAD-4.0.0 | 3.18461E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77731E-05 | None | 0 | 0 | 0 | 1.43332E-05 | 0 |
| F/L | 14098 |
Ig-91 |
45 | rs764819276 |
0.9515 | -1.713 | 0.826 | N | 0.518 | 0.392 | 0.276898752692 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| F/L | 14098 |
Ig-91 |
45 | rs764819276 |
0.9515 | -1.713 | 0.826 | N | 0.518 | 0.392 | 0.276898752692 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| F/L | 14098 |
Ig-91 |
45 | rs764819276 |
0.9515 | -1.713 | 0.826 | N | 0.518 | 0.392 | 0.276898752692 | gnomAD-4.0.0 | 4.33918E-06 | None | None | None | None | N | None | 0 | 1.66767E-05 | None | 0 | 0 | None | 0 | 0 | 5.08696E-06 | 0 | 0 |
| F/S | 14098 |
Ig-91 |
45 | None | 0.7835 | None | 0.959 | N | 0.545 | 0.478 | 0.787347168989 | gnomAD-4.0.0 | 4.77692E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.58025E-06 | 0 | 0 |
| V/G | 14187 |
Ig-92 |
46 | rs755713534 |
0.6146 | -2.242 | 0.997 | D | 0.685 | 0.572 | 0.854271221731 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/G | 14187 |
Ig-92 |
46 | rs755713534 |
0.6146 | -2.242 | 0.997 | D | 0.685 | 0.572 | 0.854271221731 | gnomAD-4.0.0 | 1.59195E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| V/I | 14187 |
Ig-92 |
46 | None | 0.0979 | None | 0.987 | N | 0.495 | 0.262 | 0.676633843901 | gnomAD-4.0.0 | 1.36868E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79924E-06 | 0 | 0 |
| C/G | 14364 |
Ig-94 |
46 | rs1454558974 |
0.5255 | -2.241 | 0.971 | N | 0.76 | 0.261 | 0.679282971961 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/G | 14364 |
Ig-94 |
46 | rs1454558974 |
0.5255 | -2.241 | 0.971 | N | 0.76 | 0.261 | 0.679282971961 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/G | 14364 |
Ig-94 |
46 | rs1454558974 |
0.5255 | -2.241 | 0.971 | N | 0.76 | 0.261 | 0.679282971961 | gnomAD-4.0.0 | 6.57367E-06 | None | None | None | None | N | None | 2.41231E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 14364 |
Ig-94 |
46 | None | 0.7186 | None | 0.991 | N | 0.771 | 0.296 | 0.686119149826 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 14364 |
Ig-94 |
46 | rs1462387608 |
0.5909 | -1.46 | 0.991 | N | 0.672 | 0.337 | 0.523961927912 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 14364 |
Ig-94 |
46 | rs1462387608 |
0.5909 | -1.46 | 0.991 | N | 0.672 | 0.337 | 0.523961927912 | gnomAD-4.0.0 | 1.59364E-06 | None | None | None | None | N | None | 0 | 2.28843E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 14453 |
Ig-95 |
46 | rs777429220 |
0.1901 | -2.057 | 0.612 | D | 0.614 | 0.326 | 0.422283790207 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| F/C | 14453 |
Ig-95 |
46 | rs777429220 |
0.1901 | -2.057 | 0.612 | D | 0.614 | 0.326 | 0.422283790207 | gnomAD-4.0.0 | 3.18369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86574E-05 | 0 |
| F/L | 14453 |
Ig-95 |
46 | rs878966051 |
0.371 | None | None | N | 0.188 | 0.193 | 0.37262878642 | gnomAD-4.0.0 | 1.59184E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85964E-06 | 0 | 0 |
| V/L | 14542 |
Ig-96 |
46 | None | 0.2884 | None | 0.09 | D | 0.493 | 0.165 | 0.407767136052 | gnomAD-4.0.0 | 1.60164E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.804E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 14631 |
Ig-97 |
46 | None | 0.0856 | None | 0.012 | N | 0.521 | 0.082 | 0.306695030598 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/V | 14631 |
Ig-97 |
46 | rs1237863283 |
0.078 | None | None | N | 0.181 | 0.183 | 0.0920862733494 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/V | 14631 |
Ig-97 |
46 | rs1237863283 |
0.078 | None | None | N | 0.181 | 0.183 | 0.0920862733494 | gnomAD-4.0.0 | 1.23982E-06 | None | None | None | None | N | None | 1.33561E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47759E-07 | 0 | 0 |
| C/F | 14720 |
Ig-98 |
46 | rs752834664 |
0.4332 | -1.288 | 0.994 | N | 0.849 | 0.404 | 0.402614778071 | gnomAD-2.1.1 | 1.7E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.68E-05 | 0 |
| C/F | 14720 |
Ig-98 |
46 | rs752834664 |
0.4332 | -1.288 | 0.994 | N | 0.849 | 0.404 | 0.402614778071 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/F | 14720 |
Ig-98 |
46 | rs752834664 |
0.4332 | -1.288 | 0.994 | N | 0.849 | 0.404 | 0.402614778071 | gnomAD-4.0.0 | 1.93823E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.29545E-05 | 1.14927E-05 | 4.84152E-05 |
| V/L | 14809 |
Ig-99 |
45 | rs775225695 |
0.3335 | -0.424 | 0.898 | N | 0.485 | 0.138 | 0.566443977814 | gnomAD-2.1.1 | 5.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.61E-05 | None | 0 | 0 | 0 |
| V/L | 14809 |
Ig-99 |
45 | rs775225695 |
0.3335 | -0.424 | 0.898 | N | 0.485 | 0.138 | 0.566443977814 | gnomAD-3.1.2 | 6.6E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07641E-04 | 0 |
| V/L | 14809 |
Ig-99 |
45 | rs775225695 |
0.3335 | -0.424 | 0.898 | N | 0.485 | 0.138 | 0.566443977814 | gnomAD-4.0.0 | 6.46488E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.27662E-04 | 0 |
| V/M | 14809 |
Ig-99 |
45 | rs775225695 |
0.2308 | None | 0.993 | D | 0.747 | 0.374 | 0.628821965753 | gnomAD-3.1.2 | 6.6E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/M | 14809 |
Ig-99 |
45 | rs775225695 |
0.2308 | None | 0.993 | D | 0.747 | 0.374 | 0.628821965753 | gnomAD-4.0.0 | 6.46488E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.9245E-06 | 0 | 3.35132E-05 |
| Y/C | 14898 |
Ig-100 |
46 | None | 0.4159 | None | 1.0 | D | 0.826 | 0.656 | 0.657572108434 | gnomAD-4.0.0 | 1.59355E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86252E-06 | 0 | 0 |
| Y/H | 14898 |
Ig-100 |
46 | rs752146866 |
0.4115 | -2.107 | 1.0 | N | 0.728 | 0.489 | 0.436993770938 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Y/H | 14898 |
Ig-100 |
46 | rs752146866 |
0.4115 | -2.107 | 1.0 | N | 0.728 | 0.489 | 0.436993770938 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| Y/C | 14987 |
Ig-101 |
46 | None | 0.3938 | None | 1.0 | D | 0.782 | 0.607 | 0.662894048667 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| Y/H | 15076 |
Ig-102 |
46 | None | 0.3528 | None | 0.916 | N | 0.621 | 0.425 | 0.443797312901 | gnomAD-4.0.0 | 1.36932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79984E-06 | 0 | 0 |
| Y/C | 15165 |
Ig-103 |
46 | None | 0.4757 | None | 1.0 | D | 0.8 | 0.535 | 0.630178222335 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| V/A | 15347 |
Ig-105 |
46 | None | 0.471 | None | 0.104 | N | 0.611 | 0.276 | 0.676464442291 | gnomAD-4.0.0 | 2.05422E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.48004E-05 | 0 |
| V/G | 15347 |
Ig-105 |
46 | rs375367475 |
0.5301 | -2.695 | 0.667 | N | 0.748 | 0.491 | None | gnomAD-2.1.1 | 6.45E-05 | None | None | None | None | N | None | 7.4491E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/G | 15347 |
Ig-105 |
46 | rs375367475 |
0.5301 | -2.695 | 0.667 | N | 0.748 | 0.491 | None | gnomAD-3.1.2 | 2.30427E-04 | None | None | None | None | N | None | 8.21296E-04 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/G | 15347 |
Ig-105 |
46 | rs375367475 |
0.5301 | -2.695 | 0.667 | N | 0.748 | 0.491 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| V/G | 15347 |
Ig-105 |
46 | rs375367475 |
0.5301 | -2.695 | 0.667 | N | 0.748 | 0.491 | None | gnomAD-4.0.0 | 3.41103E-05 | None | None | None | None | N | None | 6.94166E-04 | 1.67006E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.20461E-05 |
| V/I | 15347 |
Ig-105 |
46 | None | 0.0716 | None | None | N | 0.166 | 0.111 | 0.278968121808 | gnomAD-4.0.0 | 1.36948E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00022E-07 | 0 | 1.65843E-05 |
| Y/C | 15436 |
Ig-106 |
46 | None | 0.6438 | None | 1.0 | D | 0.793 | 0.696 | 0.603487413129 | gnomAD-4.0.0 | 1.60326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.46417E-05 | 0 |
| Y/H | 15436 |
Ig-106 |
46 | rs748548136 |
0.6748 | -1.625 | 1.0 | D | 0.734 | 0.556 | 0.441844919209 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 6.5E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/H | 15436 |
Ig-106 |
46 | rs748548136 |
0.6748 | -1.625 | 1.0 | D | 0.734 | 0.556 | 0.441844919209 | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 4.83E-05 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/H | 15436 |
Ig-106 |
46 | rs748548136 |
0.6748 | -1.625 | 1.0 | D | 0.734 | 0.556 | 0.441844919209 | gnomAD-4.0.0 | 5.59456E-06 | None | None | None | None | N | None | 1.07173E-04 | 1.68731E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 15436 |
Ig-106 |
46 | rs748548136 |
0.7633 | -2.744 | 1.0 | D | 0.825 | 0.673 | 0.718952573792 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 0 | 2.96E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Y/N | 15436 |
Ig-106 |
46 | rs748548136 |
0.7633 | -2.744 | 1.0 | D | 0.825 | 0.673 | 0.718952573792 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 15436 |
Ig-106 |
46 | rs748548136 |
0.7633 | -2.744 | 1.0 | D | 0.825 | 0.673 | 0.718952573792 | gnomAD-4.0.0 | 3.10809E-06 | None | None | None | None | N | None | 0 | 5.06192E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.21213E-05 |
| H/R | 15525 |
Ig-107 |
46 | rs1313832139 |
0.5486 | None | 0.773 | N | 0.501 | 0.295 | 0.28798054836 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.95084E-04 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 15525 |
Ig-107 |
46 | rs1313832139 |
0.5486 | None | 0.773 | N | 0.501 | 0.295 | 0.28798054836 | gnomAD-4.0.0 | 2.03062E-06 | None | None | None | None | N | None | 1.74899E-05 | 0 | None | 0 | 1.14207E-04 | None | 0 | 0 | 0 | 0 | 0 |
| H/Y | 15525 |
Ig-107 |
46 | rs1413462312 |
0.0918 | 1.009 | 0.001 | N | 0.136 | 0.229 | 0.176091768786 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65948E-04 |
| H/Y | 15525 |
Ig-107 |
46 | rs1413462312 |
0.0918 | 1.009 | 0.001 | N | 0.136 | 0.229 | 0.176091768786 | gnomAD-4.0.0 | 1.5938E-06 | None | None | None | None | N | None | 0 | 2.28802E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 17001 |
Ig-111 |
47 | None | 0.1592 | None | 0.655 | N | 0.527 | 0.084 | 0.344483371355 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/F | 17718 |
Ig-113 |
42 | rs757223139 |
0.3551 | -1.367 | 0.968 | N | 0.732 | 0.372 | 0.71530076483 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| V/F | 17718 |
Ig-113 |
42 | rs757223139 |
0.3551 | -1.367 | 0.968 | N | 0.732 | 0.372 | 0.71530076483 | gnomAD-4.0.0 | 1.59229E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77331E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/G | 17718 |
Ig-113 |
42 | None | 0.4098 | None | 0.811 | D | 0.702 | 0.437 | 0.781884890362 | gnomAD-4.0.0 | 2.05322E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69919E-06 | 0 | 0 |
| V/I | 17718 |
Ig-113 |
42 | rs757223139 |
0.1038 | -0.586 | 0.64 | N | 0.579 | 0.238 | 0.491523185611 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/I | 17718 |
Ig-113 |
42 | rs757223139 |
0.1038 | -0.586 | 0.64 | N | 0.579 | 0.238 | 0.491523185611 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 17718 |
Ig-113 |
42 | rs757223139 |
0.1038 | -0.586 | 0.64 | N | 0.579 | 0.238 | 0.491523185611 | gnomAD-4.0.0 | 6.57929E-06 | None | None | None | None | N | None | 0 | 6.55566E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/G | 18738 |
Ig-116 |
51 | rs777956655 |
0.5378 | -1.767 | 0.928 | N | 0.721 | 0.631 | None | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| V/G | 18738 |
Ig-116 |
51 | rs777956655 |
0.5378 | -1.767 | 0.928 | N | 0.721 | 0.631 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| V/G | 18738 |
Ig-116 |
51 | rs777956655 |
0.5378 | -1.767 | 0.928 | N | 0.721 | 0.631 | None | gnomAD-4.0.0 | 8.97572E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.67667E-05 | 0 | 0 |
| T/A | 19433 |
Ig-118 |
43 | None | 0.1348 | None | 0.78 | N | 0.554 | 0.139 | 0.338834610459 | gnomAD-4.0.0 | 2.05301E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69869E-06 | 0 | 0 |
| I/L | 19833 |
Ig-119 |
44 | rs2050442222 |
0.2581 | None | 0.104 | D | 0.237 | 0.214 | 0.32082282376 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94099E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 19833 |
Ig-119 |
44 | rs2050442222 |
0.2581 | None | 0.104 | D | 0.237 | 0.214 | 0.32082282376 | gnomAD-4.0.0 | 2.56307E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.85625E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 19833 |
Ig-119 |
44 | None | 0.6403 | None | 0.999 | N | 0.724 | 0.554 | 0.904533080692 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.17284E-04 | 0 | 0 | 0 |
| V/G | 20523 |
Ig-121 |
45 | rs1461050183 |
0.2927 | None | 0.968 | N | 0.738 | 0.482 | 0.666713593321 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/G | 20523 |
Ig-121 |
45 | rs1461050183 |
0.2927 | None | 0.968 | N | 0.738 | 0.482 | 0.666713593321 | gnomAD-4.0.0 | 7.43992E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01743E-05 | 0 | 0 |
| V/M | 20523 |
Ig-121 |
45 | rs2049899591 |
0.1724 | None | 0.984 | N | 0.605 | 0.246 | 0.497021753114 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 20523 |
Ig-121 |
45 | rs2049899591 |
0.1724 | None | 0.984 | N | 0.605 | 0.246 | 0.497021753114 | gnomAD-4.0.0 | 6.57687E-06 | None | None | None | None | N | None | 2.41383E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 21910 |
Ig-125 |
45 | rs749668988 |
0.1214 | None | None | N | 0.093 | 0.126 | 0.608671624233 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/R | 21910 |
Ig-125 |
45 | None | 0.2786 | None | 0.002 | N | 0.345 | 0.427 | 0.73443042151 | gnomAD-4.0.0 | 6.85237E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65953E-05 |
| I/T | 21910 |
Ig-125 |
45 | rs146941600 |
0.3273 | -2.579 | 0.007 | N | 0.237 | 0.169 | None | gnomAD-2.1.1 | 1.91954E-04 | None | None | None | None | N | None | 8.36E-05 | 8.59E-05 | None | 0 | 2.16564E-03 | None | 6.59E-05 | None | 0 | 0 | 7.12454E-04 |
| I/T | 21910 |
Ig-125 |
45 | rs146941600 |
0.3273 | -2.579 | 0.007 | N | 0.237 | 0.169 | None | gnomAD-3.1.2 | 2.82872E-04 | None | None | None | None | N | None | 4.83E-05 | 1.63827E-03 | 0 | 0 | 1.93874E-03 | None | 0 | 0 | 1.47E-05 | 0 | 2.39693E-03 |
| I/T | 21910 |
Ig-125 |
45 | rs146941600 |
0.3273 | -2.579 | 0.007 | N | 0.237 | 0.169 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 2E-03 | 0 | None | None | None | 0 | None |
| I/T | 21910 |
Ig-125 |
45 | rs146941600 |
0.3273 | -2.579 | 0.007 | N | 0.237 | 0.169 | None | gnomAD-4.0.0 | 1.50173E-04 | None | None | None | None | N | None | 4.00224E-05 | 4.68353E-04 | None | 0 | 1.12349E-03 | None | 0 | 0 | 6.78774E-06 | 1.10069E-05 | 2.43722E-03 |
| I/V | 21910 |
Ig-125 |
45 | rs749668988 |
0.088 | -1.471 | 0.001 | N | 0.149 | 0.091 | 0.436671004673 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.07E-06 | 0 |
| L/P | 22308 |
Ig-126 |
44 | None | 0.8894 | None | 1.0 | N | 0.825 | 0.725 | 0.718142918398 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 22994 |
Ig-128 |
45 | rs183056142 |
0.0846 | 0.118 | None | N | 0.274 | 0.11 | None | gnomAD-2.1.1 | 5E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 6.18876E-04 | None | 0 | None | 0 | 0 | 1.40489E-04 |
| T/I | 22994 |
Ig-128 |
45 | rs183056142 |
0.0846 | 0.118 | None | N | 0.274 | 0.11 | None | gnomAD-3.1.2 | 1.25447E-04 | None | None | None | None | N | None | 0 | 6.61E-05 | 0 | 0 | 3.50058E-03 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 22994 |
Ig-128 |
45 | rs183056142 |
0.0846 | 0.118 | None | N | 0.274 | 0.11 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| T/I | 22994 |
Ig-128 |
45 | rs183056142 |
0.0846 | 0.118 | None | N | 0.274 | 0.11 | None | gnomAD-4.0.0 | 2.73443E-04 | None | None | None | None | N | None | 0 | 3.34158E-05 | None | 0 | 9.72502E-03 | None | 0 | 0 | 0 | 0 | 6.40512E-05 |
| A/G | 23389 |
Ig-129 |
45 | rs1194442496 |
0.2101 | None | 0.067 | N | 0.369 | 0.216 | 0.216624796971 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/G | 23389 |
Ig-129 |
45 | rs1194442496 |
0.2101 | None | 0.067 | N | 0.369 | 0.216 | 0.216624796971 | gnomAD-4.0.0 | 1.31543E-05 | None | None | None | None | N | None | 2.41394E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47093E-05 | 0 | 0 |
| A/T | 23389 |
Ig-129 |
45 | rs1709937178 |
0.4853 | None | 0.994 | N | 0.667 | 0.291 | 0.333651784274 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 24076 |
Ig-131 |
48 | rs202098308 |
0.0934 | -1.677 | 0.64 | N | 0.596 | 0.114 | None | gnomAD-2.1.1 | 7.17E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.00497E-04 | 1.17531E-04 | 0 |
| L/V | 24076 |
Ig-131 |
48 | rs202098308 |
0.0934 | -1.677 | 0.64 | N | 0.596 | 0.114 | None | gnomAD-3.1.2 | 6.57E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47085E-04 | 0 | 0 |
| L/V | 24076 |
Ig-131 |
48 | rs202098308 |
0.0934 | -1.677 | 0.64 | N | 0.596 | 0.114 | None | gnomAD-4.0.0 | 4.90226E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.876E-04 | 0 | 5.51612E-05 | 0 | 3.20698E-05 |
| L/S | 25158 |
Ig-134 |
48 | None | 0.3568 | None | 0.967 | N | 0.679 | 0.525 | 0.783148497913 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 7.32654E-05 |
| I/F | 25844 |
Ig-136 |
47 | rs1216073181 |
0.2674 | None | None | N | 0.218 | 0.256 | 0.187945064343 | gnomAD-4.0.0 | 1.59197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85977E-06 | 0 | 0 |
| I/V | 25844 |
Ig-136 |
47 | rs1216073181 |
0.0696 | -1.611 | None | N | 0.115 | 0.217 | 0.203808441222 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
| I/V | 25844 |
Ig-136 |
47 | rs1216073181 |
0.0696 | -1.611 | None | N | 0.115 | 0.217 | 0.203808441222 | gnomAD-4.0.0 | 1.59197E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02535E-05 |
| C/Y | 26240 |
Ig-137 |
48 | rs1575695077 |
0.2401 | None | None | N | 0.273 | 0.093 | 0.220303561663 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 26240 |
Ig-137 |
48 | rs1575695077 |
0.2401 | None | None | N | 0.273 | 0.093 | 0.220303561663 | gnomAD-4.0.0 | 3.11452E-06 | None | None | None | None | N | None | 0 | 3.41227E-05 | None | 0 | 0 | None | 0 | 0 | 2.54993E-06 | 0 | 0 |
| V/L | 26926 |
Ig-139 |
47 | rs769499232 |
0.1802 | -0.912 | None | N | 0.163 | 0.143 | 0.239901079897 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.89842E-04 | None | 0 | None | 0 | 0 | 0 |
| V/L | 26926 |
Ig-139 |
47 | rs769499232 |
0.1802 | -0.912 | None | N | 0.163 | 0.143 | 0.239901079897 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.86698E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 26926 |
Ig-139 |
47 | rs769499232 |
0.1802 | -0.912 | None | N | 0.163 | 0.143 | 0.239901079897 | gnomAD-4.0.0 | 8.05718E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.8979E-04 | None | 0 | 0 | 0 | 0 | 0 |
| M/T | 27323 |
Ig-140 |
46 | rs1176526187 |
0.1815 | -1.718 | 0.994 | N | 0.691 | 0.485 | 0.724833077695 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| M/T | 27323 |
Ig-140 |
46 | rs1176526187 |
0.1815 | -1.718 | 0.994 | N | 0.691 | 0.485 | 0.724833077695 | gnomAD-4.0.0 | 3.18262E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
| V/A | 28009 |
Ig-142 |
47 | rs1337839201 |
0.5508 | -1.793 | 0.999 | N | 0.539 | 0.477 | 0.69600953434 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 28009 |
Ig-142 |
47 | rs1337839201 |
0.5508 | -1.793 | 0.999 | N | 0.539 | 0.477 | 0.69600953434 | gnomAD-4.0.0 | 1.85981E-06 | None | None | None | None | N | None | 1.33583E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09856E-05 | 1.60185E-05 |
| V/D | 28009 |
Ig-142 |
47 | None | 0.909 | -1.397 | 1.0 | N | 0.81 | 0.671 | 0.890010646008 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.64E-05 | None | 0 | None | 0 | 0 | 0 |
| V/D | 28009 |
Ig-142 |
47 | None | 0.909 | -1.397 | 1.0 | N | 0.81 | 0.671 | 0.890010646008 | gnomAD-4.0.0 | 1.36892E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52832E-05 | None | 0 | 0 | 8.99643E-07 | 0 | 0 |
| V/F | 28009 |
Ig-142 |
47 | rs770470074 |
0.2747 | -1.411 | 1.0 | D | 0.786 | 0.441 | 0.85955502653 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| V/F | 28009 |
Ig-142 |
47 | rs770470074 |
0.2747 | -1.411 | 1.0 | D | 0.786 | 0.441 | 0.85955502653 | gnomAD-4.0.0 | 6.84472E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16034E-05 | 0 |
| V/G | 28009 |
Ig-142 |
47 | rs1337839201 |
0.5724 | None | 1.0 | D | 0.78 | 0.66 | 0.920757238843 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/G | 28009 |
Ig-142 |
47 | rs1337839201 |
0.5724 | None | 1.0 | D | 0.78 | 0.66 | 0.920757238843 | gnomAD-4.0.0 | 6.57626E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47046E-05 | 0 | 0 |
| V/I | 28009 |
Ig-142 |
47 | None | 0.0766 | None | 0.997 | N | 0.551 | 0.297 | 0.595871345579 | gnomAD-4.0.0 | 6.84472E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99628E-07 | 0 | 0 |
| T/I | 28404 |
Ig-143 |
47 | rs368218177 |
0.1255 | 0.18 | None | N | 0.265 | 0.092 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 28404 |
Ig-143 |
47 | rs368218177 |
0.1255 | 0.18 | None | N | 0.265 | 0.092 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 28404 |
Ig-143 |
47 | rs368218177 |
0.1255 | 0.18 | None | N | 0.265 | 0.092 | None | gnomAD-4.0.0 | 2.02998E-06 | None | None | None | None | N | None | 1.74789E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20493E-06 | 0 | 0 |
| F/S | 29091 |
Ig-145 |
47 | None | 0.8325 | None | 1.0 | D | 0.791 | 0.619 | 0.78271780837 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| V/A | 29487 |
Ig-146 |
44 | rs2154153415 |
0.3362 | None | 0.165 | N | 0.589 | 0.256 | 0.680330652673 | gnomAD-4.0.0 | 2.73706E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.57691E-05 | None | 0 | 0 | 8.99468E-07 | 0 | 0 |
| V/L | 29487 |
Ig-146 |
44 | rs200899806 |
0.165 | -0.738 | None | N | 0.157 | 0.1 | 0.32082282376 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 29487 |
Ig-146 |
44 | rs200899806 |
0.165 | -0.738 | None | N | 0.157 | 0.1 | 0.32082282376 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/L | 29487 |
Ig-146 |
44 | rs200899806 |
0.165 | -0.738 | None | N | 0.157 | 0.1 | 0.32082282376 | gnomAD-4.0.0 | 6.84272E-07 | None | None | None | None | N | None | 0 | 2.23664E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 29487 |
Ig-146 |
44 | None | 0.1773 | -0.776 | 0.457 | N | 0.653 | 0.092 | None | gnomAD-2.1.1 | 6.93754E-04 | None | None | None | None | N | None | 4.13E-05 | 1.13276E-03 | None | 8.13323E-03 | 0 | None | 0 | None | 0 | 4.3839E-04 | 1.82944E-03 |
| V/M | 29487 |
Ig-146 |
44 | None | 0.1773 | -0.776 | 0.457 | N | 0.653 | 0.092 | None | gnomAD-3.1.2 | 9.00522E-04 | None | None | None | None | N | None | 4.83E-05 | 4.45551E-03 | 0 | 1.15274E-02 | 0 | None | 0 | 0 | 3.82173E-04 | 0 | 4.78469E-04 |
| V/M | 29487 |
Ig-146 |
44 | None | 0.1773 | -0.776 | 0.457 | N | 0.653 | 0.092 | None | gnomAD-4.0.0 | 6.04261E-04 | None | None | None | None | N | None | 4.00481E-05 | 1.90089E-03 | None | 8.34459E-03 | 0 | None | 0 | 0 | 4.62796E-04 | 0 | 1.0409E-03 |
| V/L | 30178 |
Ig-148 |
47 | None | 0.1661 | None | 0.001 | N | 0.175 | 0.161 | 0.389750110748 | gnomAD-4.0.0 | 1.64371E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94822E-06 | 0 | 0 |
| M/I | 30573 |
Ig-149 |
42 | rs756674702 |
0.1344 | -1.515 | None | N | 0.083 | 0.082 | 0.364141725642 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| M/I | 30573 |
Ig-149 |
42 | rs756674702 |
0.1344 | -1.515 | None | N | 0.083 | 0.082 | 0.364141725642 | gnomAD-4.0.0 | 1.59126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85838E-06 | 0 | 0 |
| V/E | 31262 |
Ig-151 |
45 | None | 0.7306 | None | 0.484 | D | 0.68 | 0.571 | 0.784914850903 | gnomAD-4.0.0 | 3.18217E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71556E-06 | 0 | 0 |
| V/G | 31262 |
Ig-151 |
45 | None | 0.509 | None | 0.317 | N | 0.696 | 0.525 | 0.767050086336 | gnomAD-4.0.0 | 1.59108E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88253E-05 | 0 | 0 | 0 | 0 |
| V/D | 31662 |
Ig-152 |
42 | rs1164809267 |
0.7339 | -1.643 | 0.484 | N | 0.707 | 0.655 | 0.79693206861 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| V/D | 31662 |
Ig-152 |
42 | rs1164809267 |
0.7339 | -1.643 | 0.484 | N | 0.707 | 0.655 | 0.79693206861 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/D | 31662 |
Ig-152 |
42 | rs1164809267 |
0.7339 | -1.643 | 0.484 | N | 0.707 | 0.655 | 0.79693206861 | gnomAD-4.0.0 | 2.56243E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78638E-06 | 0 | 0 |
| V/L | 31662 |
Ig-152 |
42 | None | 0.1684 | None | 0.004 | N | 0.383 | 0.061 | 0.515938915144 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/E | 32059 |
Ig-153 |
43 | rs769741768 |
0.9689 | -0.674 | 0.984 | D | 0.607 | 0.376 | 0.603512723014 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| A/E | 32059 |
Ig-153 |
43 | rs769741768 |
0.9689 | -0.674 | 0.984 | D | 0.607 | 0.376 | 0.603512723014 | gnomAD-4.0.0 | 4.77427E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71742E-06 | 0 | 3.02517E-05 |
| V/I | 32353 |
Ig-154 |
47 | rs1250490166 |
0.0777 | -0.724 | 0.003 | N | 0.217 | 0.053 | 0.313210971179 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| V/I | 32353 |
Ig-154 |
47 | rs1250490166 |
0.0777 | -0.724 | 0.003 | N | 0.217 | 0.053 | 0.313210971179 | gnomAD-4.0.0 | 1.36841E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51915E-05 | None | 0 | 0 | 8.99473E-07 | 0 | 0 |
| A/T | 32749 |
Ig-155 |
42 | rs1693506739 |
0.4656 | None | 1.0 | N | 0.704 | 0.317 | 0.542675667512 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/F | 33243 |
Ig-157 |
41 | None | 0.2134 | None | 0.851 | N | 0.631 | 0.18 | 0.557129077062 | gnomAD-4.0.0 | 1.59163E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85876E-06 | 0 | 0 |
| Y/H | 33543 |
Ig-158 |
48 | None | 0.5219 | None | 0.994 | D | 0.528 | 0.451 | 0.488477830397 | gnomAD-4.0.0 | 1.5917E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85896E-06 | 0 | 0 |
| Y/D | 33642 |
Ig-159 |
47 | rs774270109 |
0.9369 | -3.443 | 1.0 | N | 0.776 | 0.622 | 0.813587418085 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Y/D | 33642 |
Ig-159 |
47 | rs774270109 |
0.9369 | -3.443 | 1.0 | N | 0.776 | 0.622 | 0.813587418085 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| Y/D | 33642 |
Ig-159 |
47 | rs774270109 |
0.9369 | -3.443 | 1.0 | N | 0.776 | 0.622 | 0.813587418085 | gnomAD-4.0.0 | 3.09845E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23808E-06 | 0 | 0 |
| Y/C | 34307 |
Ig-161 |
50 | None | 0.7123 | None | 1.0 | D | 0.871 | 0.626 | 0.781510581047 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 34307 |
Ig-161 |
50 | rs769306235 |
0.8301 | -2.769 | 1.0 | D | 0.884 | 0.658 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.66E-05 | 0 |
| Y/N | 34307 |
Ig-161 |
50 | rs769306235 |
0.8301 | -2.769 | 1.0 | D | 0.884 | 0.658 | None | gnomAD-4.0.0 | 1.84726E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.33846E-05 | 0 | 1.65645E-05 |
| I/T | 34409 |
Ig-162 |
47 | rs879013405 |
0.1742 | -2.204 | 0.324 | N | 0.509 | 0.335 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 34409 |
Ig-162 |
47 | rs879013405 |
0.1742 | -2.204 | 0.324 | N | 0.509 | 0.335 | None | gnomAD-4.0.0 | 2.05287E-06 | None | None | None | None | N | None | 0 | 2.23614E-05 | None | 0 | 0 | None | 0 | 0 | 8.99418E-07 | 1.15931E-05 | 0 |
| I/L | 34988 |
Ig-163 |
47 | rs1420224634 |
0.2694 | -0.94 | 0.675 | N | 0.326 | 0.191 | 0.580864329964 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| I/L | 34988 |
Ig-163 |
47 | rs1420224634 |
0.2694 | -0.94 | 0.675 | N | 0.326 | 0.191 | 0.580864329964 | gnomAD-4.0.0 | 6.84143E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51889E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/N | 34988 |
Ig-163 |
47 | None | 0.8841 | None | 0.988 | N | 0.589 | 0.511 | 0.818383550975 | gnomAD-4.0.0 | 4.77271E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.31716E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 34988 |
Ig-163 |
47 | None | 0.193 | None | 0.675 | N | 0.336 | 0.168 | 0.567643136482 | gnomAD-4.0.0 | 2.05243E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69821E-06 | 0 | 0 |
| H/Q | 35175 |
Ig-164 |
47 | rs1215297501 |
0.2838 | None | 0.938 | N | 0.587 | 0.225 | 0.241078983079 | gnomAD-4.0.0 | 3.18173E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71497E-06 | 0 | 0 |
| H/Y | 35175 |
Ig-164 |
47 | None | 0.1024 | None | 0.001 | N | 0.156 | 0.099 | 0.188950314367 | gnomAD-4.0.0 | 1.59087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02334E-05 |
| V/A | 35748 |
Ig-168 |
47 | None | 0.2562 | None | 0.024 | N | 0.463 | 0.318 | 0.515149029962 | gnomAD-4.0.0 | 1.59286E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43968E-05 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.