Structural position:

  • Domain Type: Ig
  • Aligned Position: 134
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
D/G 157 Ig-2 54 None 0.4191 None 0.059 N 0.583 0.308 0.253205268125 gnomAD-4.0.0 1.20032E-06 None None None -0.431(TCAP) N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/N 157 Ig-2 54 rs1471570172 0.1867 -0.526 0.003 N 0.229 0.165 0.229924730088 gnomAD-2.1.1 3.98E-06 None None None -1.322(TCAP) N None 0 0 None 0 0 None 0 None 0 8.79E-06 0
D/N 157 Ig-2 54 rs1471570172 0.1867 -0.526 0.003 N 0.229 0.165 0.229924730088 gnomAD-3.1.2 6.57E-06 None None None -1.322(TCAP) N None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
D/N 157 Ig-2 54 rs1471570172 0.1867 -0.526 0.003 N 0.229 0.165 0.229924730088 gnomAD-4.0.0 4.33674E-06 None None None -1.322(TCAP) N None 0 0 None 0 0 None 0 0 4.23725E-06 2.19606E-05 0
G/E 996 Ig-3 54 None 0.5477 None 0.235 D 0.504 0.472 0.638114607455 gnomAD-4.0.0 6.36215E-06 None None None None N None 0 0 None 0 0 None 0 0 1.14264E-05 0 0
G/R 996 Ig-3 54 None 0.537 None 0.993 D 0.768 0.468 0.814224319965 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/A 1137 Ig-4 56 None 0.6724 None 1.0 D 0.699 0.515 0.3571064206 gnomAD-4.0.0 1.36825E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79867E-06 0 0
G/D 1137 Ig-4 56 rs864309575 0.9531 None 1.0 N 0.829 0.616 0.378498632473 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/D 1137 Ig-4 56 rs864309575 0.9531 None 1.0 N 0.829 0.616 0.378498632473 gnomAD-4.0.0 3.71741E-06 None None None None N None 0 0 None 0 0 None 0 0 5.08493E-06 0 0
G/R 1137 Ig-4 56 rs72647870 0.9197 -0.95 1.0 D 0.805 0.71 None gnomAD-2.1.1 2.24058E-03 None None None None N None 2.80381E-04 6.77469E-04 None 1.73678E-03 0 None 3.27E-05 None 3.90283E-03 3.63752E-03 2.21976E-03
G/R 1137 Ig-4 56 rs72647870 0.9197 -0.95 1.0 D 0.805 0.71 None gnomAD-3.1.2 2.294E-03 None None None None N None 3.61987E-04 9.8219E-04 0 3.4622E-03 0 None 3.86865E-03 3.16456E-03 3.85147E-03 0 1.43678E-03
G/R 1137 Ig-4 56 rs72647870 0.9197 -0.95 1.0 D 0.805 0.71 None 1000 genomes 9.98403E-04 None None None None N None 0 0 None None 0 5E-03 None None None 0 None
G/R 1137 Ig-4 56 rs72647870 0.9197 -0.95 1.0 D 0.805 0.71 None gnomAD-4.0.0 3.01681E-03 None None None None N None 3.86481E-04 7.4985E-04 None 1.8924E-03 0 None 4.10938E-03 1.65017E-04 3.63666E-03 2.19597E-05 2.91209E-03
G/S 1137 Ig-4 56 rs72647870 0.5349 -1.622 1.0 N 0.745 0.565 0.353125101423 gnomAD-2.1.1 2.39E-05 None None None None N None 0 0 None 0 1.09051E-04 None 3.27E-05 None 0 2.64E-05 0
G/S 1137 Ig-4 56 rs72647870 0.5349 -1.622 1.0 N 0.745 0.565 0.353125101423 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/S 1137 Ig-4 56 rs72647870 0.5349 -1.622 1.0 N 0.745 0.565 0.353125101423 gnomAD-4.0.0 2.41658E-05 None None None None N None 1.33486E-05 0 None 0 4.45911E-05 None 0 0 2.88148E-05 2.19587E-05 0
G/D 1345 Ig-5 55 rs36021856 0.9329 -1.349 1.0 D 0.827 0.679 None gnomAD-2.1.1 1.12591E-02 None None None None N None 1.00208E-03 1.63888E-03 None 8.70575E-04 0 None 7.1886E-04 None 6.99139E-02 9.38605E-03 1.39121E-02
G/D 1345 Ig-5 55 rs36021856 0.9329 -1.349 1.0 D 0.827 0.679 None gnomAD-3.1.2 1.01921E-02 None None None None N None 1.20633E-03 4.38424E-03 0 2.88184E-04 0 None 7.59207E-02 0 8.93644E-03 6.21375E-04 8.60421E-03
G/D 1345 Ig-5 55 rs36021856 0.9329 -1.349 1.0 D 0.827 0.679 None 1000 genomes 3.79393E-03 None None None None N None 0 4.3E-03 None None 0 1.59E-02 None None None 0 None
G/D 1345 Ig-5 55 rs36021856 0.9329 -1.349 1.0 D 0.827 0.679 None gnomAD-4.0.0 8.28819E-03 None None None None N None 1.0661E-03 2.21608E-03 None 7.76922E-04 0 None 6.74607E-02 9.89772E-04 6.99693E-03 5.81932E-04 8.15948E-03
G/A 1511 Ig-6 55 rs751606948 0.8427 -0.87 1.0 D 0.697 0.521 0.456830177556 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
G/A 1511 Ig-6 55 rs751606948 0.8427 -0.87 1.0 D 0.697 0.521 0.456830177556 gnomAD-4.0.0 1.36835E-06 None None None None N None 0 0 None 0 0 None 0 1.7337E-04 0 0 1.6564E-05
G/D 1511 Ig-6 55 rs751606948 0.9571 -1.557 1.0 D 0.86 0.644 0.490701487448 gnomAD-2.1.1 1.42E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.11E-05 0
G/D 1511 Ig-6 55 rs751606948 0.9571 -1.557 1.0 D 0.86 0.644 0.490701487448 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.88E-05 0 0
G/D 1511 Ig-6 55 rs751606948 0.9571 -1.557 1.0 D 0.86 0.644 0.490701487448 gnomAD-4.0.0 4.46159E-05 None None None None N None 0 0 None 0 0 None 0 0 5.2545E-05 0 1.60092E-04
G/S 1511 Ig-6 55 rs1045727624 0.6744 None 1.0 D 0.769 0.533 0.458013479912 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/A 1758 Ig-8 56 None 0.945 None 1.0 D 0.694 0.797 0.505151966591 gnomAD-4.0.0 2.05246E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.47794E-05 0
G/A 1893 Ig-9 53 None 0.7913 None 1.0 D 0.554 0.539 0.330069100803 gnomAD-4.0.0 1.36815E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79863E-06 0 0
G/D 1893 Ig-9 53 None 0.9263 None 1.0 N 0.592 0.613 0.344710718752 gnomAD-4.0.0 2.05223E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69794E-06 0 0
G/S 1893 Ig-9 53 rs1380250256 0.4931 -0.397 1.0 D 0.621 0.619 0.328222422547 gnomAD-2.1.1 3.98E-06 None None None None I None 0 2.89E-05 None 0 0 None 0 None 0 0 0
G/S 1893 Ig-9 53 rs1380250256 0.4931 -0.397 1.0 D 0.621 0.619 0.328222422547 gnomAD-4.0.0 1.36815E-06 None None None None I None 0 2.23594E-05 None 0 0 None 0 0 8.99311E-07 0 0
N/H 2132 Ig-10 55 None 0.1763 None 0.121 N 0.347 0.193 0.224531998449 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 3.66327E-05
Q/R 2408 Ig-13 53 rs777244038 0.2156 -0.115 0.549 N 0.416 0.134 0.208000267992 gnomAD-2.1.1 5.18E-05 None None None None N None 0 0 None 0 0 None 4.24642E-04 None 0 0 0
Q/R 2408 Ig-13 53 rs777244038 0.2156 -0.115 0.549 N 0.416 0.134 0.208000267992 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06868E-04 0
Q/R 2408 Ig-13 53 rs777244038 0.2156 -0.115 0.549 N 0.416 0.134 0.208000267992 gnomAD-4.0.0 3.09798E-05 None None None None N None 0 0 None 0 0 None 0 0 0 5.48896E-04 0
T/A 2498 Ig-14 54 rs943280773 0.0992 -1.129 0.002 N 0.163 0.199 0.16115917748 gnomAD-2.1.1 3.98E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
T/A 2498 Ig-14 54 rs943280773 0.0992 -1.129 0.002 N 0.163 0.199 0.16115917748 gnomAD-4.0.0 4.77205E-06 None None None None N None 5.65355E-05 2.28707E-05 None 0 0 None 0 0 2.85672E-06 0 0
T/I 2498 Ig-14 54 rs1160698032 0.3083 -0.143 0.934 D 0.467 0.461 0.600369781234 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 5.45E-05 None 0 None 0 0 0
T/I 2498 Ig-14 54 rs1160698032 0.3083 -0.143 0.934 D 0.467 0.461 0.600369781234 gnomAD-4.0.0 6.84105E-07 None None None None N None 0 0 None 0 2.52067E-05 None 0 0 0 0 0
T/P 2498 Ig-14 54 None 0.1627 None 0.966 D 0.469 0.438 0.519133540473 gnomAD-4.0.0 3.18137E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71344E-06 0 0
T/S 2498 Ig-14 54 None 0.1084 None 0.136 N 0.192 0.168 0.227934060464 gnomAD-4.0.0 1.36821E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79864E-06 0 0
K/N 2585 Ig-15 53 rs2091789577 0.346 None 0.982 N 0.661 0.296 0.27479166964 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
K/N 2585 Ig-15 53 rs2091789577 0.346 None 0.982 N 0.661 0.296 0.27479166964 gnomAD-4.0.0 6.57177E-06 None None None None N None 0 6.54622E-05 None 0 0 None 0 0 0 0 0
H/D 2672 Ig-16 52 rs1257617585 0.1394 -0.131 0.007 N 0.389 0.177 0.168933306366 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.8E-06 0
H/D 2672 Ig-16 52 rs1257617585 0.1394 -0.131 0.007 N 0.389 0.177 0.168933306366 gnomAD-4.0.0 1.59058E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8566E-06 0 0
T/I 2760 Ig-17 54 None 0.2601 None 0.096 D 0.438 0.142 0.412715890961 gnomAD-4.0.0 1.36814E-06 None None None None N None 2.98686E-05 0 None 0 0 None 0 0 8.99295E-07 0 0
K/E 2847 Ig-18 53 rs794729582 0.9617 -0.117 0.996 N 0.641 0.441 0.477219869099 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 5.44E-05 None 0 None 0 0 0
K/E 2847 Ig-18 53 rs794729582 0.9617 -0.117 0.996 N 0.641 0.441 0.477219869099 gnomAD-4.0.0 2.73624E-06 None None None None N None 0 0 None 0 2.51915E-05 None 0 0 2.69788E-06 0 0
K/R 2934 Ig-19 53 rs2091195170 0.1935 None 0.64 N 0.229 0.341 0.273070737957 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 6.17284E-04 0 0 0
L/F 3021 Ig-20 53 None 0.1382 None 0.991 N 0.678 0.197 0.571034400148 gnomAD-4.0.0 1.5906E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
Y/D 3110 Ig-21 53 rs2090779143 0.7511 None 0.966 N 0.561 0.531 0.720176921917 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
Y/D 3110 Ig-21 53 rs2090779143 0.7511 None 0.966 N 0.561 0.531 0.720176921917 gnomAD-4.0.0 2.56156E-06 None None None None N None 3.38398E-05 0 None 0 0 None 0 0 0 0 0
R/K 3201 Ig-22 55 rs2090450408 0.3852 None 0.061 N 0.171 0.208 0.348983352498 gnomAD-4.0.0 1.59054E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.0217E-05
R/S 3201 Ig-22 55 rs1349281831 0.9719 -0.743 0.92 D 0.428 0.353 0.451692371253 gnomAD-2.1.1 3.98E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
R/S 3201 Ig-22 55 rs1349281831 0.9719 -0.743 0.92 D 0.428 0.353 0.451692371253 gnomAD-4.0.0 1.59055E-06 None None None None N None 0 2.28645E-05 None 0 0 None 0 0 0 0 0
Q/K 3292 Ig-23 54 None 0.109 None 0.826 N 0.314 0.307 0.281780670237 gnomAD-4.0.0 1.59053E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
Q/R 3292 Ig-23 54 rs794729586 0.1314 0.042 0.92 N 0.258 0.335 None gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.82E-06 0
Q/R 3292 Ig-23 54 rs794729586 0.1314 0.042 0.92 N 0.258 0.335 None gnomAD-4.0.0 4.77161E-06 None None None None N None 0 0 None 0 0 None 0 0 8.56952E-06 0 0
D/A 3397 Ig-24 53 rs759238193 0.5261 -0.732 0.998 D 0.701 0.752 0.683586615836 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
D/A 3397 Ig-24 53 rs759238193 0.5261 -0.732 0.998 D 0.701 0.752 0.683586615836 gnomAD-4.0.0 1.59074E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8569E-06 0 0
D/E 3397 Ig-24 53 rs773862320 0.3381 -0.48 0.619 N 0.314 0.426 0.307966526162 gnomAD-2.1.1 7.97E-06 None None None None N None 0 0 None 0 0 None 6.53E-05 None 0 0 0
D/E 3397 Ig-24 53 rs773862320 0.3381 -0.48 0.619 N 0.314 0.426 0.307966526162 gnomAD-4.0.0 6.15703E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.9562E-05 4.96787E-05
G/D 3520 Ig-25 56 None 0.6134 None None None None 0.219 None gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/S 3520 Ig-25 56 rs375297413 0.3098 None None None None 0.194 None gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
N/H 3713 Ig-26 54 rs2086928931 0.1224 None None None None 0.136 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/H 3713 Ig-26 54 rs2086928931 0.1224 None None None None 0.136 None gnomAD-4.0.0 6.57056E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4699E-05 0 0
D/H 3873 Ig-27 54 rs1435923406 0.1693 None 0.317 N 0.543 0.143 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/H 3873 Ig-27 54 rs1435923406 0.1693 None 0.317 N 0.543 0.143 None gnomAD-4.0.0 6.57186E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46994E-05 0 0
G/S 3992 Ig-28 55 rs774085575 0.1937 -1.386 1.0 D 0.775 0.454 None gnomAD-2.1.1 2.14E-05 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 3.13E-05 1.40568E-04
G/S 3992 Ig-28 55 rs774085575 0.1937 -1.386 1.0 D 0.775 0.454 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 3.16456E-03 0 0 0
G/S 3992 Ig-28 55 rs774085575 0.1937 -1.386 1.0 D 0.775 0.454 None gnomAD-4.0.0 1.7972E-05 None None None None N None 0 0 None 0 0 None 0 1.64366E-04 2.03418E-05 4.39136E-05 0
N/H 4657 Ig-29 52 rs200204761 0.1325 -1.102 0.602 D 0.474 0.22 None gnomAD-2.1.1 2.47713E-03 None None None None N None 1.6544E-04 3.12767E-04 None 1.07737E-03 0 None 1.78018E-02 None 1.21007E-04 8.2393E-04 2.26372E-03
N/H 4657 Ig-29 52 rs200204761 0.1325 -1.102 0.602 D 0.474 0.22 None gnomAD-3.1.2 9.00025E-04 None None None None N None 9.65E-05 3.92722E-04 2.19298E-03 2.88184E-04 0 None 4.70278E-04 0 6.46735E-04 1.55151E-02 0
N/H 4657 Ig-29 52 rs200204761 0.1325 -1.102 0.602 D 0.474 0.22 None 1000 genomes 2.99521E-03 None None None None N None 0 0 None None 0 0 None None None 1.53E-02 None
N/H 4657 Ig-29 52 rs200204761 0.1325 -1.102 0.602 D 0.474 0.22 None gnomAD-4.0.0 1.52586E-03 None None None None N None 1.06695E-04 3.50631E-04 None 8.4786E-04 0 None 9.38879E-05 5.291E-03 6.24379E-04 1.69715E-02 1.38028E-03
N/K 4657 Ig-29 52 None 0.2583 None None N 0.094 0.144 None gnomAD-4.0.0 1.60093E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8806E-06 0 0
N/T 4657 Ig-29 52 None 0.1976 None 0.081 N 0.295 0.249 None gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Y/C 4753 Ig-30 54 rs752678561 0.2537 0.06 0.978 N 0.472 0.345 0.528461186488 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
Y/C 4753 Ig-30 54 rs752678561 0.2537 0.06 0.978 N 0.472 0.345 0.528461186488 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
Y/C 4753 Ig-30 54 rs752678561 0.2537 0.06 0.978 N 0.472 0.345 0.528461186488 gnomAD-4.0.0 2.47889E-06 None None None None N None 0 0 None 0 0 None 1.56226E-05 0 1.69522E-06 1.09789E-05 0
Y/F 4753 Ig-30 54 None 0.134 None 0.001 N 0.2 0.267 0.27855597813 gnomAD-4.0.0 1.36851E-06 None None None None N None 0 0 None 0 2.52398E-05 None 0 0 0 0 1.65689E-05
K/T 4941 Ig-32 54 None 0.3885 None 1.0 D 0.724 0.467 0.499281839539 gnomAD-4.0.0 1.36856E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.31884E-05 0
S/C 5035 Ig-33 55 None 0.2051 None 0.997 D 0.485 0.454 0.502443086328 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
S/F 5035 Ig-33 55 rs2081161682 0.2934 None 0.876 D 0.546 0.291 0.601095518603 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
S/F 5035 Ig-33 55 rs2081161682 0.2934 None 0.876 D 0.546 0.291 0.601095518603 gnomAD-4.0.0 6.57229E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07125E-04 0
S/T 5035 Ig-33 55 None 0.1124 None 0.801 N 0.425 0.214 0.279370189704 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/F 5128 Ig-34 54 rs750710170 0.1373 -0.773 0.484 N 0.539 0.442 0.716185225888 gnomAD-2.1.1 2.01E-05 None None None None N None 0 1.15962E-04 None 0 5.57E-05 None 0 None 0 0 0
S/F 5128 Ig-34 54 rs750710170 0.1373 -0.773 0.484 N 0.539 0.442 0.716185225888 gnomAD-3.1.2 1.31E-05 None None None None N None 0 1.30993E-04 0 0 0 None 0 0 0 0 0
S/F 5128 Ig-34 54 rs750710170 0.1373 -0.773 0.484 N 0.539 0.442 0.716185225888 gnomAD-4.0.0 8.96925E-06 None None None None N None 0 1.18648E-04 None 0 0 None 0 0 0 0 0
G/A 5221 Ig-35 54 rs771186700 0.1446 -0.182 0.939 D 0.574 0.378 0.470237251169 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/A 5221 Ig-35 54 rs771186700 0.1446 -0.182 0.939 D 0.574 0.378 0.470237251169 gnomAD-4.0.0 6.8419E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15934E-05 0
G/D 5221 Ig-35 54 None 0.1873 -0.252 0.885 D 0.65 0.388 0.523806315272 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
G/D 5221 Ig-35 54 None 0.1873 -0.252 0.885 D 0.65 0.388 0.523806315272 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/D 5221 Ig-35 54 None 0.1873 -0.252 0.885 D 0.65 0.388 0.523806315272 gnomAD-4.0.0 1.23935E-05 None None None None N None 0 0 None 0 0 None 0 0 1.69521E-05 0 0
G/V 5221 Ig-35 54 rs771186700 0.3569 -0.069 0.885 D 0.681 0.424 0.717421235427 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
G/V 5221 Ig-35 54 rs771186700 0.3569 -0.069 0.885 D 0.681 0.424 0.717421235427 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/V 5221 Ig-35 54 rs771186700 0.3569 -0.069 0.885 D 0.681 0.424 0.717421235427 gnomAD-4.0.0 1.79706E-05 None None None None N None 0 0 None 0 0 None 0 0 2.45805E-05 0 0
N/D 5314 Ig-36 54 rs371044267 0.2286 0.053 0.98 N 0.559 0.34 None gnomAD-2.1.1 1.28718E-04 None None None None N None 0 9.27751E-04 None 0 0 None 0 None 0 0 0
N/D 5314 Ig-36 54 rs371044267 0.2286 0.053 0.98 N 0.559 0.34 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.96438E-04 0 0 0 None 0 0 0 0 0
N/D 5314 Ig-36 54 rs371044267 0.2286 0.053 0.98 N 0.559 0.34 None gnomAD-4.0.0 4.35539E-05 None None None None N None 0 5.76252E-04 None 0 0 None 0 0 0 0 0
N/S 5314 Ig-36 54 None 0.1246 None 0.659 N 0.305 0.237 0.271763555656 gnomAD-4.0.0 3.42106E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59787E-06 0 1.65673E-05
G/C 5410 Ig-37 54 None 0.5969 None 1.0 D 0.707 0.505 0.786423769647 gnomAD-4.0.0 6.84302E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99496E-07 0 0
S/F 5597 Ig-39 55 rs754116386 0.2281 -0.846 0.988 D 0.535 0.385 None gnomAD-2.1.1 2.5E-05 None None None None N None 0 2.83E-05 None 0 0 None 0 None 0 4.69E-05 0
S/F 5597 Ig-39 55 rs754116386 0.2281 -0.846 0.988 D 0.535 0.385 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/F 5597 Ig-39 55 rs754116386 0.2281 -0.846 0.988 D 0.535 0.385 None gnomAD-4.0.0 2.47882E-05 None None None None N None 0 5.0005E-05 None 0 0 None 0 0 3.13618E-05 0 0
S/P 5597 Ig-39 55 rs757304144 0.4107 -0.521 0.998 N 0.437 0.44 0.489174143269 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
H/Y 5690 Ig-40 54 None 0.081 None 0.013 N 0.254 0.14 0.144782658237 gnomAD-4.0.0 1.3684E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79895E-06 0 0
N/I 5783 Ig-41 54 None 0.6599 None 0.998 N 0.775 0.564 0.671502058982 gnomAD-4.0.0 6.84202E-07 None None None None N None 0 0 None 0 0 None 1.87259E-05 0 0 0 0
N/S 5783 Ig-41 54 None 0.1072 None 0.961 D 0.553 0.26 0.330589388543 gnomAD-4.0.0 2.05261E-06 None None None None N None 2.98846E-05 0 None 0 0 None 0 0 1.79892E-06 0 0
T/A 5876 Ig-42 54 rs1376088246 0.0765 None 0.09 N 0.413 0.154 0.263140351381 gnomAD-4.0.0 1.36851E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79906E-06 0 0
N/S 5972 Ig-43 54 rs1447713863 0.1836 None 0.999 N 0.637 0.289 0.374255764437 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 5972 Ig-43 54 rs1447713863 0.1836 None 0.999 N 0.637 0.289 0.374255764437 gnomAD-4.0.0 3.04486E-06 None None None None N None 0 0 None 0 0 None 0 0 3.61475E-06 0 0
T/A 6065 Ig-44 54 None 0.0797 None 0.76 N 0.531 0.089 0.231231049324 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/N 6065 Ig-44 54 None 0.1045 None 0.322 N 0.272 0.206 0.332646915603 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/A 6159 Ig-45 55 rs1214856110 0.1979 -0.261 0.64 N 0.56 0.449 0.467074840246 gnomAD-2.1.1 3.19E-05 None None None None N None 0 1.17924E-03 None 0 0 None 0 None 0 0 0
G/A 6159 Ig-45 55 rs1214856110 0.1979 -0.261 0.64 N 0.56 0.449 0.467074840246 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
G/A 6159 Ig-45 55 rs1214856110 0.1979 -0.261 0.64 N 0.56 0.449 0.467074840246 gnomAD-4.0.0 6.57367E-06 None None None None N None 0 6.5505E-05 None 0 0 None 0 0 0 0 0
G/D 6159 Ig-45 55 None 0.1722 None 0.811 N 0.631 0.405 0.510346895759 gnomAD-4.0.0 1.43226E-05 None None None None N None 0 0 None 0 2.49653E-04 None 0 0 0 0 0
S/C 6345 Ig-47 54 None 0.1166 None 0.56 N 0.424 0.293 0.433047596574 gnomAD-4.0.0 6.84564E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99687E-07 0 0
S/G 6345 Ig-47 54 rs1447554517 0.0579 -0.565 0.005 N 0.264 0.084 0.117506650769 gnomAD-2.1.1 4.05E-06 None None None None N None 0 2.92E-05 None 0 0 None 0 None 0 0 0
S/G 6345 Ig-47 54 rs1447554517 0.0579 -0.565 0.005 N 0.264 0.084 0.117506650769 gnomAD-4.0.0 1.36913E-06 None None None None N None 0 2.24155E-05 None 0 0 None 0 0 0 0 1.65793E-05
S/R 6345 Ig-47 54 None 0.2004 None None N 0.206 0.11 0.115124310173 gnomAD-4.0.0 1.59315E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86053E-06 0 0
S/L 6627 Ig-50 54 rs773143754 0.1038 -0.162 0.037 N 0.307 0.259 None gnomAD-2.1.1 1.43E-05 None None None None N None 0 5.66E-05 None 0 1.02491E-04 None 0 None 0 0 0
S/L 6627 Ig-50 54 rs773143754 0.1038 -0.162 0.037 N 0.307 0.259 None gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.93424E-04 None 0 0 0 0 0
S/L 6627 Ig-50 54 rs773143754 0.1038 -0.162 0.037 N 0.307 0.259 None gnomAD-4.0.0 9.919E-06 None None None None N None 0 1.66761E-05 None 0 2.22975E-05 None 0 0 2.54363E-06 8.7885E-05 4.80507E-05
S/L 6721 Ig-51 55 None 0.1472 None 0.027 N 0.43 0.377 0.6450407448 gnomAD-4.0.0 6.84445E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9973E-07 0 0
F/L 6814 Ig-52 54 rs1371961339 0.6308 -0.74 0.048 N 0.199 0.175 0.406945738958 gnomAD-4.0.0 1.59269E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86058E-06 0 0
F/V 6814 Ig-52 54 rs1371961339 0.1881 None 0.143 N 0.407 0.14 0.554437859526 gnomAD-4.0.0 1.59269E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86058E-06 0 0
N/S 6908 Ig-53 55 rs755380607 0.1702 -0.623 0.999 N 0.653 0.24 None gnomAD-2.1.1 8.05E-06 None None None None N None 1.294E-04 0 None 0 0 None 0 None 0 0 0
N/S 6908 Ig-53 55 rs755380607 0.1702 -0.623 0.999 N 0.653 0.24 None gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
N/S 6908 Ig-53 55 rs755380607 0.1702 -0.623 0.999 N 0.653 0.24 None gnomAD-4.0.0 1.85964E-06 None None None None N None 2.67044E-05 0 None 0 0 None 0 0 8.47794E-07 0 0
N/T 6908 Ig-53 55 None 0.3051 None 0.999 N 0.71 0.447 0.562131562789 gnomAD-4.0.0 1.36889E-06 None None None None N None 2.99115E-05 0 None 0 0 None 0 0 0 0 1.65717E-05
K/R 7001 Ig-54 54 rs200594798 0.0827 -0.198 0.642 N 0.336 0.108 None gnomAD-2.1.1 2.46363E-04 None None None None N None 2.77043E-03 5.66E-05 None 0 0 None 0 None 0 0 0
K/R 7001 Ig-54 54 rs200594798 0.0827 -0.198 0.642 N 0.336 0.108 None gnomAD-3.1.2 6.44152E-04 None None None None N None 2.31649E-03 1.31044E-04 0 0 0 None 0 0 0 0 0
K/R 7001 Ig-54 54 rs200594798 0.0827 -0.198 0.642 N 0.336 0.108 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
K/R 7001 Ig-54 54 rs200594798 0.0827 -0.198 0.642 N 0.336 0.108 None gnomAD-4.0.0 1.33867E-04 None None None None N None 2.69312E-03 1.16709E-04 None 0 0 None 0 0 8.47744E-07 0 9.60707E-05
N/K 7097 Ig-55 54 rs773211607 0.4887 0.003 0.822 N 0.581 0.29 0.139678290688 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
N/K 7097 Ig-55 54 rs773211607 0.4887 0.003 0.822 N 0.581 0.29 0.139678290688 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
N/K 7097 Ig-55 54 rs773211607 0.4887 0.003 0.822 N 0.581 0.29 0.139678290688 gnomAD-4.0.0 2.47909E-06 None None None None N None 0 1.66744E-05 None 0 2.22896E-05 None 0 0 0 0 3.20287E-05
N/S 7376 Ig-58 54 rs765538868 0.1093 -0.588 0.96 N 0.489 0.211 0.206339911435 gnomAD-2.1.1 1.21E-05 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 1.78E-05 0
N/S 7376 Ig-58 54 rs765538868 0.1093 -0.588 0.96 N 0.489 0.211 0.206339911435 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/S 7376 Ig-58 54 rs765538868 0.1093 -0.588 0.96 N 0.489 0.211 0.206339911435 gnomAD-4.0.0 2.56393E-06 None None None None N None 1.69182E-05 0 None 0 0 None 0 0 2.39451E-06 0 0
N/D 7472 Ig-59 54 rs1174856533 0.2248 None 0.979 N 0.579 0.32 0.362758974969 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/D 7472 Ig-59 54 rs1174856533 0.2248 None 0.979 N 0.579 0.32 0.362758974969 gnomAD-4.0.0 2.56343E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78835E-06 0 0
S/A 7662 Ig-61 55 None 0.1079 None 0.498 N 0.507 0.269 0.328222422547 gnomAD-4.0.0 1.59238E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4334E-05 0
F/S 7755 Ig-62 54 None 0.1398 None 0.002 N 0.247 0.302 0.441017621159 gnomAD-4.0.0 6.84277E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99549E-07 0 0
F/Y 7755 Ig-62 54 None 0.1009 None 0.51 N 0.358 0.112 0.423360453849 gnomAD-4.0.0 6.84277E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99549E-07 0 0
K/E 7942 Ig-64 54 rs780339774 0.1591 0.605 0.005 D 0.196 0.115 0.260249123532 gnomAD-2.1.1 4.02E-05 None None None None N None 0 0 None 0 0 None 3.26797E-04 None 0 0 0
K/E 7942 Ig-64 54 rs780339774 0.1591 0.605 0.005 D 0.196 0.115 0.260249123532 gnomAD-4.0.0 2.18951E-05 None None None None N None 0 0 None 0 0 None 0 0 0 3.70989E-04 0
K/E 8224 Ig-67 54 rs1373569910 0.2036 0.238 0.016 N 0.15 0.169 0.268211541103 gnomAD-4.0.0 1.59135E-06 None None None None N None 0 2.28676E-05 None 0 0 None 0 0 0 0 0
N/I 8317 Ig-68 54 rs1278554973 0.8024 0.219 1.0 N 0.769 0.509 0.746569793032 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
N/I 8317 Ig-68 54 rs1278554973 0.8024 0.219 1.0 N 0.769 0.509 0.746569793032 gnomAD-4.0.0 4.10542E-06 None None None None N None 2.989E-05 0 None 0 0 None 0 0 4.49755E-06 0 0
N/K 8317 Ig-68 54 rs370154022 0.518 0.091 0.999 N 0.59 0.374 0.0716867268079 gnomAD-2.1.1 1.61E-05 None None None None N None 2.58331E-04 0 None 0 0 None 0 None 0 0 0
N/K 8317 Ig-68 54 rs370154022 0.518 0.091 0.999 N 0.59 0.374 0.0716867268079 gnomAD-3.1.2 7.89E-05 None None None None N None 2.89645E-04 0 0 0 0 None 0 0 0 0 0
N/K 8317 Ig-68 54 rs370154022 0.518 0.091 0.999 N 0.59 0.374 0.0716867268079 gnomAD-4.0.0 1.11553E-05 None None None None N None 2.13658E-04 0 None 0 0 None 0 0 1.69532E-06 0 0
N/K 8413 Ig-69 54 rs772142595 0.4901 0.066 0.006 N 0.197 0.131 0.158396225186 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 6.56E-05 None 0 0 0
N/K 8413 Ig-69 54 rs772142595 0.4901 0.066 0.006 N 0.197 0.131 0.158396225186 gnomAD-4.0.0 3.1847E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.8687E-05 0
N/Y 8413 Ig-69 54 rs971543383 0.3736 None 0.762 D 0.722 0.411 0.70240400353 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/Y 8413 Ig-69 54 rs971543383 0.3736 None 0.762 D 0.722 0.411 0.70240400353 gnomAD-4.0.0 2.56372E-06 None None None None N None 1.69216E-05 0 None 0 0 None 0 0 0 0 2.84706E-05
N/D 8509 Ig-70 54 None 0.2001 None 0.198 N 0.325 0.243 0.253726318573 gnomAD-4.0.0 1.59167E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85915E-06 0 0
S/L 8603 Ig-71 55 rs781354478 0.0996 0.144 0.934 D 0.581 0.372 0.684870435166 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.66E-05 0
S/L 8603 Ig-71 55 rs781354478 0.0996 0.144 0.934 D 0.581 0.372 0.684870435166 gnomAD-3.1.2 1.32E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 2.07814E-04 0
S/L 8603 Ig-71 55 rs781354478 0.0996 0.144 0.934 D 0.581 0.372 0.684870435166 gnomAD-4.0.0 6.81796E-06 None None None None N None 1.33622E-05 0 None 0 2.22955E-05 None 0 0 4.23852E-06 4.3928E-05 0
S/P 8603 Ig-71 55 rs748398405 0.6667 -0.758 0.826 N 0.611 0.378 0.352693368174 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
S/P 8603 Ig-71 55 rs748398405 0.6667 -0.758 0.826 N 0.611 0.378 0.352693368174 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
S/P 8603 Ig-71 55 rs748398405 0.6667 -0.758 0.826 N 0.611 0.378 0.352693368174 gnomAD-4.0.0 6.57324E-06 None None None None N None 2.4122E-05 0 None 0 0 None 0 0 0 0 0
S/W 8603 Ig-71 55 None 0.3874 None 0.998 D 0.706 0.487 0.797057192974 gnomAD-4.0.0 6.84275E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99549E-07 0 0
N/D 8790 Ig-73 55 rs772728050 0.1199 0.276 0.048 D 0.394 0.173 0.211220785272 gnomAD-2.1.1 2.15E-05 None None None None N None 0 0 None 0 3.07377E-04 None 0 None 0 0 0
N/D 8790 Ig-73 55 rs772728050 0.1199 0.276 0.048 D 0.394 0.173 0.211220785272 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92604E-04 None 0 0 0 0 0
N/D 8790 Ig-73 55 rs772728050 0.1199 0.276 0.048 D 0.394 0.173 0.211220785272 gnomAD-4.0.0 2.47876E-06 None None None None N None 0 0 None 0 8.91107E-05 None 0 0 0 0 0
N/H 8979 Ig-75 54 rs376982715 0.182 -0.998 0.999 N 0.681 0.287 None gnomAD-2.1.1 1.35664E-04 None None None None N None 4.14E-05 5.67E-05 None 0 0 None 0 None 0 2.73181E-04 0
N/H 8979 Ig-75 54 rs376982715 0.182 -0.998 0.999 N 0.681 0.287 None gnomAD-3.1.2 1.7744E-04 None None None None N None 4.82E-05 1.96618E-04 0 0 0 None 0 0 3.08705E-04 0 4.78011E-04
N/H 8979 Ig-75 54 rs376982715 0.182 -0.998 0.999 N 0.681 0.287 None gnomAD-4.0.0 3.3091E-04 None None None None N None 2.66482E-05 1.33387E-04 None 0 0 None 0 0 4.35684E-04 0 1.60056E-04
N/S 8979 Ig-75 54 rs749174522 0.1242 -0.627 0.978 N 0.541 0.259 0.241078983079 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
N/S 8979 Ig-75 54 rs749174522 0.1242 -0.627 0.978 N 0.541 0.259 0.241078983079 gnomAD-4.0.0 1.36852E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99504E-07 0 1.65667E-05
K/N 9165 Ig-77 54 None 0.1922 None 0.001 N 0.145 0.086 0.0611884634855 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
N/K 9258 Ig-78 54 rs749135942 0.4573 0.216 0.379 N 0.271 0.123 0.165133752707 gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 0 None 9.28E-05 8.86E-06 0
N/K 9258 Ig-78 54 rs749135942 0.4573 0.216 0.379 N 0.271 0.123 0.165133752707 gnomAD-4.0.0 2.73685E-06 None None None None N None 0 0 None 0 0 None 5.6184E-05 0 0 0 1.65673E-05
N/T 9258 Ig-78 54 None 0.3205 None 0.549 N 0.283 0.226 0.376216005999 gnomAD-4.0.0 1.36843E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79896E-06 0 0
N/S 9354 Ig-79 54 None 0.1042 None 0.716 None 0.545 0.322 0.225902525712 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/K 9450 Ig-80 54 None 0.4782 None 0.896 None 0.592 0.332 0.28297238246 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/S 9450 Ig-80 54 None 0.2477 None 0.811 None 0.535 0.24 0.276065633971 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 6.17284E-04 0 0 0
N/T 9450 Ig-80 54 rs2076533329 0.3806 None 0.103 None 0.289 0.205 0.275641507738 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
N/T 9450 Ig-80 54 rs2076533329 0.3806 None 0.103 None 0.289 0.205 0.275641507738 gnomAD-4.0.0 6.57186E-06 None None None None N None 0 6.54622E-05 None 0 0 None 0 0 0 0 0
N/K 9547 Ig-81 55 rs727505185 0.7345 -0.031 0.992 None 0.604 0.26 0.168933306366 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.85E-06 0
N/K 9547 Ig-81 55 rs727505185 0.7345 -0.031 0.992 None 0.604 0.26 0.168933306366 gnomAD-4.0.0 1.59109E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85802E-06 0 0
G/A 9643 Ig-82 54 rs1190523795 0.3969 -0.518 0.201 None 0.609 0.25 0.227260227426 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
G/A 9643 Ig-82 54 rs1190523795 0.3969 -0.518 0.201 None 0.609 0.25 0.227260227426 gnomAD-4.0.0 4.78933E-06 None None None None N None 0 2.23744E-05 None 0 0 None 0 0 5.39657E-06 0 0
D/E 9752 Ig-83 55 None 0.1968 None 0.835 None 0.383 0.146 0.185906805712 gnomAD-4.0.0 6.84157E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99418E-07 0 0
D/N 9752 Ig-83 55 rs1420103092 0.1292 0.183 0.996 None 0.483 0.317 None gnomAD-2.1.1 6.37E-05 None None None None I None 1.14758E-04 0 None 0 0 None 0 None 0 6.48E-05 0
D/N 9752 Ig-83 55 rs1420103092 0.1292 0.183 0.996 None 0.483 0.317 None gnomAD-3.1.2 3.29E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 2.94E-05 0 0
D/N 9752 Ig-83 55 rs1420103092 0.1292 0.183 0.996 None 0.483 0.317 None gnomAD-4.0.0 1.61111E-05 None None None None I None 4.00449E-05 1.66706E-05 None 0 4.45593E-05 None 0 0 1.52562E-05 2.19568E-05 0
D/Y 9752 Ig-83 55 None 0.4192 None 0.999 None 0.648 0.384 0.459906663326 gnomAD-4.0.0 6.84159E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.15934E-05 0
K/E 10041 Ig-85 53 None 0.6872 None 0.939 None 0.585 0.238 0.290590437066 gnomAD-4.0.0 1.59087E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85752E-06 0 0
K/T 10041 Ig-85 53 None 0.5557 None 0.17 None 0.385 0.213 0.294206760003 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/H 10130 Ig-86 53 rs373355159 0.4315 -1.265 1.0 None 0.656 0.332 None gnomAD-2.1.1 1.99525E-04 None None None None N None 4.13E-05 5.65E-05 None 0 0 None 9.8E-05 None 4E-05 3.65901E-04 2.79955E-04
R/H 10130 Ig-86 53 rs373355159 0.4315 -1.265 1.0 None 0.656 0.332 None gnomAD-3.1.2 1.90634E-04 None None None None N None 7.24E-05 0 0 0 0 None 0 0 3.67485E-04 0 4.78469E-04
R/H 10130 Ig-86 53 rs373355159 0.4315 -1.265 1.0 None 0.656 0.332 None gnomAD-4.0.0 3.12305E-04 None None None None N None 6.67485E-05 4.99983E-05 None 0 0 None 9.37793E-05 0 3.94107E-04 6.58747E-05 3.04195E-04
K/N 13739 Ig-87 56 rs2060461606 0.9537 None 1.0 N 0.743 0.316 0.330331372229 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/N 13739 Ig-87 56 rs2060461606 0.9537 None 1.0 N 0.743 0.316 0.330331372229 gnomAD-4.0.0 6.57488E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47089E-05 0 0
K/R 13739 Ig-87 56 None 0.2752 None 0.999 N 0.633 0.258 0.518641613453 gnomAD-4.0.0 1.59193E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85956E-06 0 0
L/F 13833 Ig-88 54 rs1288508073 0.281 None 0.999 N 0.667 0.151 0.550210968228 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/F 13833 Ig-88 54 rs1288508073 0.281 None 0.999 N 0.667 0.151 0.550210968228 gnomAD-4.0.0 2.03017E-06 None None None None N None 0 0 None 0 0 None 0 0 2.40999E-06 0 0
L/M 13833 Ig-88 54 None 0.1859 None 0.957 N 0.293 0.096 0.334659703779 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/R 14017 Ig-90 53 rs1161979802 0.5935 None 0.034 N 0.511 0.194 0.233785782151 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/R 14017 Ig-90 53 rs1161979802 0.5935 None 0.034 N 0.511 0.194 0.233785782151 gnomAD-4.0.0 2.57034E-06 None None None None N None 1.69607E-05 0 None 0 0 None 0 0 2.39741E-06 0 0
K/N 14105 Ig-91 52 None 0.7531 None 0.606 N 0.273 0.214 0.272205846399 gnomAD-4.0.0 6.84438E-07 None None None None N None 0 0 None 0 2.52461E-05 None 0 0 0 0 0
L/V 14282 Ig-93 52 None 0.1103 None 0.891 N 0.309 0.099 0.403040389579 gnomAD-4.0.0 3.1844E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86558E-05 0
K/M 14371 Ig-94 53 rs757765087 0.5756 0.152 0.8 N 0.404 0.211 0.243972157842 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
K/M 14371 Ig-94 53 rs757765087 0.5756 0.152 0.8 N 0.404 0.211 0.243972157842 gnomAD-4.0.0 1.59299E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43349E-05 0
T/I 14460 Ig-95 53 rs1452796827 0.2544 0.166 0.996 N 0.441 0.317 0.444907495582 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
T/I 14460 Ig-95 53 rs1452796827 0.2544 0.166 0.996 N 0.441 0.317 0.444907495582 gnomAD-4.0.0 5.47451E-06 None None None None N None 0 0 None 0 0 None 0 0 7.19673E-06 0 0
K/R 14549 Ig-96 53 rs775953090 0.1099 -0.49 0.032 N 0.259 0.139 0.44770609447 gnomAD-2.1.1 4.16E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.19E-06 0
K/R 14549 Ig-96 53 rs775953090 0.1099 -0.49 0.032 N 0.259 0.139 0.44770609447 gnomAD-4.0.0 1.37305E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80272E-06 0 0
K/T 14549 Ig-96 53 rs775953090 0.4548 -0.635 0.942 D 0.616 0.291 None gnomAD-2.1.1 4.16E-06 None None None None N None 6.85E-05 0 None 0 0 None 0 None 0 0 0
K/T 14549 Ig-96 53 rs775953090 0.4548 -0.635 0.942 D 0.616 0.291 None gnomAD-4.0.0 1.37305E-06 None None None None N None 5.99018E-05 0 None 0 0 None 0 0 0 0 0
K/R 14638 Ig-97 53 rs878896650 0.0967 None 0.014 N 0.265 0.106 0.181679512989 gnomAD-4.0.0 4.10636E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39758E-06 0 0
R/G 14905 Ig-100 53 None 0.3569 None 0.549 N 0.499 0.274 0.455448229734 gnomAD-4.0.0 1.5934E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4332E-05 0
R/K 14905 Ig-100 53 None 0.124 None 0.004 N 0.141 0.135 0.266843984389 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/S 14905 Ig-100 53 rs1279690538 0.6084 None 0.379 N 0.399 0.27 0.262175524916 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/S 14905 Ig-100 53 rs1279690538 0.6084 None 0.379 N 0.399 0.27 0.262175524916 gnomAD-4.0.0 6.58527E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47249E-05 0 0
A/V 14994 Ig-101 53 None 0.144 None 0.005 N 0.155 0.106 0.428169733428 gnomAD-4.0.0 2.05514E-06 None None None None N None 0 0 None 0 2.53704E-05 None 0 0 1.80031E-06 0 0
R/P 15083 Ig-102 53 rs191551032 0.5367 None 0.999 N 0.725 0.334 0.565391359567 gnomAD-4.0.0 3.4234E-06 None None None None N None 2.99276E-05 0 None 0 0 None 0 0 3.59971E-06 0 0
R/Q 15083 Ig-102 53 rs191551032 0.1191 -0.383 0.998 N 0.658 0.23 None gnomAD-2.1.1 4.84E-05 None None None None N None 1.29316E-04 2.91E-05 None 0 1.12435E-04 None 1.63452E-04 None 0 8.93E-06 1.66445E-04
R/Q 15083 Ig-102 53 rs191551032 0.1191 -0.383 0.998 N 0.658 0.23 None gnomAD-3.1.2 6.59E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
R/Q 15083 Ig-102 53 rs191551032 0.1191 -0.383 0.998 N 0.658 0.23 None gnomAD-4.0.0 2.29483E-05 None None None None N None 5.34845E-05 5.01354E-05 None 0 2.23944E-05 None 0 0 1.61143E-05 9.88424E-05 1.60287E-05
R/W 15083 Ig-102 53 rs199834143 0.2422 -0.464 1.0 D 0.739 0.493 None gnomAD-2.1.1 7.52E-05 None None None None N None 8.27E-05 1.1352E-04 None 0 5.18E-05 None 3.27E-05 None 0 9.42E-05 1.40924E-04
R/W 15083 Ig-102 53 rs199834143 0.2422 -0.464 1.0 D 0.739 0.493 None gnomAD-3.1.2 9.23E-05 None None None None N None 9.68E-05 1.97291E-04 0 0 0 None 0 0 8.84E-05 2.07211E-04 0
R/W 15083 Ig-102 53 rs199834143 0.2422 -0.464 1.0 D 0.739 0.493 None gnomAD-4.0.0 1.01719E-04 None None None None N None 6.68861E-05 1.17006E-04 None 0 4.47708E-05 None 0 0 1.15343E-04 5.49101E-05 1.44254E-04
K/E 15172 Ig-103 53 rs766651994 0.3388 0.383 0.999 N 0.715 0.416 0.353336612579 gnomAD-2.1.1 1.08E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.35E-05 0
K/E 15172 Ig-103 53 rs766651994 0.3388 0.383 0.999 N 0.715 0.416 0.353336612579 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.95E-05 0 0
K/E 15172 Ig-103 53 rs766651994 0.3388 0.383 0.999 N 0.715 0.416 0.353336612579 gnomAD-4.0.0 1.05432E-05 None None None None N None 0 0 None 0 0 None 0 0 1.44162E-05 0 0
L/P 15260 Ig-104 53 rs552053581 0.7027 -1.001 0.966 N 0.575 0.373 0.771099386941 gnomAD-2.1.1 4.88581E-04 None None None None N None 0 2.9E-05 None 0 0 None 3.85823E-03 None 0 0 3.32447E-04
L/P 15260 Ig-104 53 rs552053581 0.7027 -1.001 0.966 N 0.575 0.373 0.771099386941 gnomAD-3.1.2 1.05485E-04 None None None None N None 2.42E-05 1.97213E-04 0 0 0 None 0 0 0 2.49584E-03 0
L/P 15260 Ig-104 53 rs552053581 0.7027 -1.001 0.966 N 0.575 0.373 0.771099386941 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
L/P 15260 Ig-104 53 rs552053581 0.7027 -1.001 0.966 N 0.575 0.373 0.771099386941 gnomAD-4.0.0 2.41241E-04 None None None None N None 1.33618E-05 6.67802E-05 None 0 0 None 0 0 1.69621E-06 3.94393E-03 3.68602E-04
L/V 15260 Ig-104 53 rs758419306 0.1304 -1.036 0.012 N 0.17 0.128 0.457650129517 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
L/V 15260 Ig-104 53 rs758419306 0.1304 -1.036 0.012 N 0.17 0.128 0.457650129517 gnomAD-3.1.2 1.32E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 1.47E-05 0 0
L/V 15260 Ig-104 53 rs758419306 0.1304 -1.036 0.012 N 0.17 0.128 0.457650129517 gnomAD-4.0.0 4.06173E-06 None None None None N None 1.75131E-05 0 None 0 0 None 0 0 3.61549E-06 0 0
Y/C 15354 Ig-105 53 rs886038861 0.2044 -0.551 0.993 N 0.464 0.381 0.601175442443 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
Y/C 15354 Ig-105 53 rs886038861 0.2044 -0.551 0.993 N 0.464 0.381 0.601175442443 gnomAD-4.0.0 1.3695E-05 None None None None N None 5.99089E-05 0 None 0 0 None 0 0 1.62004E-05 0 0
Y/H 15354 Ig-105 53 rs1324351583 0.301 -0.719 0.975 N 0.404 0.287 0.412328234245 gnomAD-2.1.1 4.04E-06 None None None None N None 0 2.91E-05 None 0 0 None 0 None 0 0 0
Y/H 15354 Ig-105 53 rs1324351583 0.301 -0.719 0.975 N 0.404 0.287 0.412328234245 gnomAD-4.0.0 1.09562E-05 None None None None N None 0 0 None 0 0 None 0 0 1.26005E-05 0 3.31697E-05
E/K 15618 Ig-108 51 None 0.139 None 0.324 N 0.422 0.242 0.326881540566 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
A/T 16016 Ig-109 49 None 0.0967 None 0.046 N 0.147 0.112 0.271763555656 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
K/N 16312 Ig-110 51 None 0.3992 None None N 0.137 0.115 0.0551355673512 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
I/V 17008 Ig-111 54 None 0.0712 None None N 0.128 0.046 0.344945010812 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/V 17330 Ig-112 80 None 0.6441 None 0.999 N 0.793 0.455 0.543120768234 gnomAD-4.0.0 1.37218E-06 None None None None N None 0 2.25723E-05 None 0 0 None 0 0 9.01024E-07 0 0
T/I 17725 Ig-113 49 None 0.2345 None 0.927 N 0.447 0.278 0.437207349437 gnomAD-4.0.0 1.59231E-06 None None None None N None 0 2.28686E-05 None 0 0 None 0 0 0 0 0
N/K 18440 Ig-115 59 rs911563094 0.2375 None 0.101 N 0.261 0.076 0.159798565429 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/K 18440 Ig-115 59 rs911563094 0.2375 None 0.101 N 0.261 0.076 0.159798565429 gnomAD-4.0.0 2.4939E-06 None None None None N None 1.3464E-05 0 None 0 0 None 0 0 2.54973E-06 0 0
N/S 18440 Ig-115 59 rs747117847 0.0983 -0.682 0.047 N 0.209 0.103 0.184867976434 gnomAD-2.1.1 4.2E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.17E-06 0
D/N 18745 Ig-116 58 rs1376102250 0.0911 None 0.999 N 0.706 0.337 0.319970858106 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 2.07211E-04 0
D/N 18745 Ig-116 58 rs1376102250 0.0911 None 0.999 N 0.706 0.337 0.319970858106 gnomAD-4.0.0 1.31563E-05 None None None None I None 0 0 None 0 0 None 0 0 1.47093E-05 2.07211E-04 0
A/V 19440 Ig-118 50 rs781642072 0.103 -0.613 0.001 N 0.269 0.153 0.353336612579 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
A/V 19440 Ig-118 50 rs781642072 0.103 -0.613 0.001 N 0.269 0.153 0.353336612579 gnomAD-4.0.0 1.59185E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85909E-06 0 0
V/A 19838 Ig-119 49 None 0.1624 None 0.061 N 0.107 0.119 0.344483371355 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
V/F 19838 Ig-119 49 rs767665016 0.1993 -0.715 0.996 N 0.253 0.327 0.717896021573 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
V/F 19838 Ig-119 49 rs767665016 0.1993 -0.715 0.996 N 0.253 0.327 0.717896021573 gnomAD-4.0.0 6.84322E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99586E-07 0 0
V/L 19838 Ig-119 49 rs767665016 0.2475 -0.182 0.826 N 0.291 0.219 0.31501682445 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.65893E-04
V/L 19838 Ig-119 49 rs767665016 0.2475 -0.182 0.826 N 0.291 0.219 0.31501682445 gnomAD-4.0.0 4.10593E-06 None None None None N None 0 0 None 0 0 None 1.87301E-05 0 4.49793E-06 0 0
F/C 20132 Ig-120 53 None 0.2326 None 0.915 N 0.521 0.284 0.704619230643 gnomAD-4.0.0 1.59223E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86028E-06 0 0
F/L 20132 Ig-120 53 rs1304980579 0.7821 -0.425 0.027 N 0.409 0.152 0.441844919209 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
F/L 20132 Ig-120 53 rs1304980579 0.7821 -0.425 0.027 N 0.409 0.152 0.441844919209 gnomAD-4.0.0 1.59225E-06 None None None None N None 0 0 None 0 2.77331E-05 None 0 0 0 0 0
P/S 20530 Ig-121 52 rs755700079 0.4136 -1.0 1.0 N 0.737 0.411 0.406394481233 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/S 20530 Ig-121 52 rs755700079 0.4136 -1.0 1.0 N 0.737 0.411 0.406394481233 gnomAD-4.0.0 4.791E-06 None None None None N None 2.99061E-05 0 None 0 0 None 0 0 5.39801E-06 0 0
P/T 20530 Ig-121 52 rs755700079 0.3741 -0.911 1.0 N 0.723 0.411 0.43923137753 gnomAD-2.1.1 2.15E-05 None None None None N None 4.14E-05 0 None 0 0 None 0 None 0 3.92E-05 0
P/T 20530 Ig-121 52 rs755700079 0.3741 -0.911 1.0 N 0.723 0.411 0.43923137753 gnomAD-3.1.2 3.29E-05 None None None None N None 9.66E-05 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 20530 Ig-121 52 rs755700079 0.3741 -0.911 1.0 N 0.723 0.411 0.43923137753 gnomAD-4.0.0 7.0671E-05 None None None None N None 6.67967E-05 0 None 0 0 None 0 0 9.07172E-05 0 3.20328E-05
D/N 20825 Ig-122 57 None 0.1189 None 0.83 N 0.735 0.216 0.44349138644 gnomAD-4.0.0 6.84326E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65695E-05
T/A 21227 Ig-123 51 rs752958666 0.179 -0.327 0.999 N 0.586 0.442 None gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
T/A 21227 Ig-123 51 rs752958666 0.179 -0.327 0.999 N 0.586 0.442 None gnomAD-3.1.2 1.32E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 1.47E-05 0 0
T/A 21227 Ig-123 51 rs752958666 0.179 -0.327 0.999 N 0.586 0.442 None gnomAD-4.0.0 4.34069E-06 None None None None N None 1.33629E-05 0 None 0 0 None 0 0 3.39152E-06 0 3.20482E-05
T/P 21227 Ig-123 51 None 0.4034 None 1.0 N 0.702 0.521 0.633985563651 gnomAD-4.0.0 6.84621E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99722E-07 0 0
T/S 21227 Ig-123 51 rs752958666 0.1555 None 0.999 N 0.619 0.36 0.472741223727 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/S 21227 Ig-123 51 rs752958666 0.1555 None 0.999 N 0.619 0.36 0.472741223727 gnomAD-4.0.0 6.57964E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4715E-05 0 0
F/L 22315 Ig-126 51 rs746811214 0.8357 None 0.166 N 0.308 0.222 0.323886383625 gnomAD-4.0.0 2.05329E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69902E-06 0 0
F/V 22315 Ig-126 51 rs746811214 0.2441 -0.263 0.491 N 0.415 0.232 0.49118058892 gnomAD-2.1.1 2.01E-05 None None None None N None 0 0 None 4.97711E-04 0 None 0 None 0 0 0
F/V 22315 Ig-126 51 rs746811214 0.2441 -0.263 0.491 N 0.415 0.232 0.49118058892 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 8.65052E-04 0 None 0 0 0 0 0
F/V 22315 Ig-126 51 rs746811214 0.2441 -0.263 0.491 N 0.415 0.232 0.49118058892 gnomAD-4.0.0 1.11583E-05 None None None None N None 0 0 None 5.07065E-04 0 None 0 0 8.47814E-07 0 3.2039E-05
T/I 23001 Ig-128 52 rs1215862556 0.2327 -0.402 1.0 N 0.766 0.457 0.584891512018 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
T/I 23001 Ig-128 52 rs1215862556 0.2327 -0.402 1.0 N 0.766 0.457 0.584891512018 gnomAD-4.0.0 2.7374E-06 None None None None N None 2.98972E-05 4.47287E-05 None 0 2.52449E-05 None 0 0 0 0 0
F/L 24083 Ig-131 55 None 0.8207 None 0.989 N 0.593 0.418 0.463243292966 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 1.94099E-04 0 None 0 0 1.3125E-06 0 0
F/V 24083 Ig-131 55 rs759548192 0.2297 -0.235 0.989 N 0.639 0.45 0.705680399256 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 6.56E-05 None 0 0 1.66611E-04
F/V 24083 Ig-131 55 rs759548192 0.2297 -0.235 0.989 N 0.639 0.45 0.705680399256 gnomAD-4.0.0 4.79262E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86952E-05 3.0349E-05
S/C 24480 Ig-132 50 rs775608256 0.268 -0.325 1.0 D 0.665 0.525 0.72625753649 gnomAD-2.1.1 2.01E-05 None None None None N None 0 0 None 0 2.7908E-04 None 0 None 0 0 0
S/C 24480 Ig-132 50 rs775608256 0.268 -0.325 1.0 D 0.665 0.525 0.72625753649 gnomAD-4.0.0 3.42166E-06 None None None None N None 0 0 None 0 1.26078E-04 None 0 0 0 0 0
N/D 24769 Ig-133 54 rs372787601 0.1431 0.165 0.042 N 0.281 0.188 None gnomAD-2.1.1 8.05E-05 None None None None N None 0 2.9E-05 None 0 0 None 3.27E-05 None 0 1.51426E-04 1.66168E-04
N/D 24769 Ig-133 54 rs372787601 0.1431 0.165 0.042 N 0.281 0.188 None gnomAD-3.1.2 5.92E-05 None None None None N None 0 6.55E-05 0 0 0 None 0 0 8.83E-05 2.07039E-04 4.77555E-04
N/D 24769 Ig-133 54 rs372787601 0.1431 0.165 0.042 N 0.281 0.188 None gnomAD-4.0.0 6.13541E-05 None None None None N None 3.99861E-05 1.66667E-05 None 0 0 None 0 9.91736E-04 6.5275E-05 3.29395E-05 1.44065E-04
N/S 24769 Ig-133 54 rs1032887625 0.0899 -0.3 0.001 N 0.138 0.114 0.187945064343 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
N/S 24769 Ig-133 54 rs1032887625 0.0899 -0.3 0.001 N 0.138 0.114 0.187945064343 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 24769 Ig-133 54 rs1032887625 0.0899 -0.3 0.001 N 0.138 0.114 0.187945064343 gnomAD-4.0.0 2.47915E-06 None None None None N None 0 0 None 0 0 None 0 0 3.39092E-06 0 0
F/L 25165 Ig-134 55 rs879163890 0.7166 -0.366 0.025 N 0.295 0.228 0.261217442401 gnomAD-2.1.1 1.07E-05 None None None None N None 1.24028E-04 0 None 0 0 None 0 None 0 0 0
F/L 25165 Ig-134 55 rs879163890 0.7166 -0.366 0.025 N 0.295 0.228 0.261217442401 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
F/L 25165 Ig-134 55 rs879163890 0.7166 -0.366 0.025 N 0.295 0.228 0.261217442401 gnomAD-4.0.0 3.84489E-06 None None None None N None 5.07786E-05 0 None 0 0 None 0 0 0 0 0
S/G 25562 Ig-135 49 rs1400963847 0.1965 -0.718 0.822 N 0.405 0.295 0.275641507738 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
S/G 25562 Ig-135 49 rs1400963847 0.1965 -0.718 0.822 N 0.405 0.295 0.275641507738 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
S/G 25562 Ig-135 49 rs1400963847 0.1965 -0.718 0.822 N 0.405 0.295 0.275641507738 gnomAD-4.0.0 6.57454E-06 None None None None N None 2.41255E-05 0 None 0 0 None 0 0 0 0 0
N/T 26644 Ig-138 51 None 0.1378 None 0.815 N 0.397 0.212 0.338834610459 gnomAD-4.0.0 1.59151E-06 None None None None N None 0 0 None 0 2.77423E-05 None 0 0 0 0 0
T/I 26933 Ig-139 54 None 0.1567 None 0.984 N 0.559 0.424 0.456462010053 gnomAD-4.0.0 1.59156E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
T/N 26933 Ig-139 54 rs1418023891 0.0988 None 0.896 N 0.526 0.253 0.322230723748 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/N 26933 Ig-139 54 rs1418023891 0.0988 None 0.896 N 0.526 0.253 0.322230723748 gnomAD-4.0.0 6.57566E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47037E-05 0 0
T/P 26933 Ig-139 54 None 0.3023 None 0.984 N 0.561 0.389 0.456830177556 gnomAD-4.0.0 3.18317E-06 None None None None N None 0 0 None 0 5.54662E-05 None 0 0 0 0 0
Q/E 27330 Ig-140 53 rs1205501595 0.07 0.075 0.005 N 0.116 0.166 0.273070737957 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
Q/E 27330 Ig-140 53 rs1205501595 0.07 0.075 0.005 N 0.116 0.166 0.273070737957 gnomAD-4.0.0 1.5913E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
T/I 28016 Ig-142 54 rs748757133 0.1708 0.037 0.983 N 0.639 0.277 0.55046033382 gnomAD-2.1.1 1.44E-05 None None None None N None 0 0 None 0 2.0749E-04 None 0 None 0 0 0
T/I 28016 Ig-142 54 rs748757133 0.1708 0.037 0.983 N 0.639 0.277 0.55046033382 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 3.861E-04 None 0 0 0 0 0
T/I 28016 Ig-142 54 rs748757133 0.1708 0.037 0.983 N 0.639 0.277 0.55046033382 gnomAD-4.0.0 3.09951E-06 None None None None N None 0 0 None 0 1.11777E-04 None 0 0 0 0 0
T/N 28016 Ig-142 54 None 0.088 None 0.967 N 0.567 0.261 0.393316636838 gnomAD-4.0.0 6.84457E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99638E-07 0 0
N/D 28411 Ig-143 54 None 0.103 None 0.014 N 0.343 0.091 0.0482279557977 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/S 28411 Ig-143 54 rs1254349060 0.0688 -0.503 None N 0.105 0.092 0.0138822411134 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/S 28411 Ig-143 54 rs1254349060 0.0688 -0.503 None N 0.105 0.092 0.0138822411134 gnomAD-4.0.0 6.56996E-06 None None None None N None 2.41161E-05 0 None 0 0 None 0 0 0 0 0
S/C 28806 Ig-144 52 rs1060500445 0.0913 -0.708 0.001 N 0.303 0.163 0.256283259241 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78011E-04
S/C 28806 Ig-144 52 rs1060500445 0.0913 -0.708 0.001 N 0.303 0.163 0.256283259241 gnomAD-4.0.0 6.57272E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 4.78011E-04
S/F 28806 Ig-144 52 rs1060500445 0.1376 None 0.484 N 0.533 0.147 0.444505407614 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
E/D 29098 Ig-145 54 rs755499990 0.0957 -0.207 0.011 N 0.178 0.054 0.187945064343 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
E/D 29098 Ig-145 54 rs755499990 0.0957 -0.207 0.011 N 0.178 0.054 0.187945064343 gnomAD-4.0.0 1.59102E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02352E-05
E/K 29098 Ig-145 54 rs369063299 0.1418 0.478 0.961 N 0.578 0.378 None gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
E/K 29098 Ig-145 54 rs369063299 0.1418 0.478 0.961 N 0.578 0.378 None gnomAD-4.0.0 4.10502E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39656E-06 0 0
E/Q 29098 Ig-145 54 rs369063299 0.1396 -0.04 0.98 D 0.535 0.231 0.361958692863 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
E/Q 29098 Ig-145 54 rs369063299 0.1396 -0.04 0.98 D 0.535 0.231 0.361958692863 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
E/Q 29098 Ig-145 54 rs369063299 0.1396 -0.04 0.98 D 0.535 0.231 0.361958692863 gnomAD-4.0.0 1.23929E-06 None None None None N None 2.6688E-05 0 None 0 0 None 0 0 0 0 0
D/E 29494 Ig-146 51 None 0.1436 None 0.003 N 0.173 0.141 0.241664281697 gnomAD-4.0.0 6.84269E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15939E-05 0
S/A 29893 Ig-147 52 rs1382237741 0.1135 None 0.052 N 0.254 0.123 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/A 29893 Ig-147 52 rs1382237741 0.1135 None 0.052 N 0.254 0.123 None gnomAD-4.0.0 3.09866E-06 None None None None N None 0 0 None 0 0 None 0 0 3.39032E-06 0 1.60102E-05
G/R 30580 Ig-149 49 rs1296437798 0.8419 -0.417 1.0 N 0.642 0.499 0.723635906084 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 0 0
G/R 30580 Ig-149 49 rs1296437798 0.8419 -0.417 1.0 N 0.642 0.499 0.723635906084 gnomAD-4.0.0 1.59126E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02389E-05
D/G 31269 Ig-151 52 None 0.1457 None 0.822 N 0.579 0.38 0.277730125212 gnomAD-4.0.0 1.59112E-06 None None None None N None 0 0 None 0 2.77423E-05 None 0 0 0 0 0
D/V 31269 Ig-151 52 rs368404585 0.2037 0.231 0.942 N 0.737 0.503 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
D/V 31269 Ig-151 52 rs368404585 0.2037 0.231 0.942 N 0.737 0.503 None gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
D/V 31269 Ig-151 52 rs368404585 0.2037 0.231 0.942 N 0.737 0.503 None gnomAD-4.0.0 1.31416E-05 None None None None N None 0 0 None 0 0 None 0 0 2.93997E-05 0 0
K/Q 31669 Ig-152 49 None 0.149 None 0.988 N 0.525 0.334 0.304760801415 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
S/N 32066 Ig-153 50 rs1438404917 0.18 0.057 0.37 N 0.259 0.124 0.238096912614 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
S/N 32066 Ig-153 50 rs1438404917 0.18 0.057 0.37 N 0.259 0.124 0.238096912614 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/N 32066 Ig-153 50 rs1438404917 0.18 0.057 0.37 N 0.259 0.124 0.238096912614 gnomAD-4.0.0 3.09874E-06 None None None None N None 0 0 None 0 0 None 0 0 4.2383E-06 0 0
S/R 32066 Ig-153 50 rs747323263 0.7544 -0.038 0.997 N 0.684 0.416 0.42886291518 gnomAD-2.1.1 7.13E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.56E-05 0
S/R 32066 Ig-153 50 rs747323263 0.7544 -0.038 0.997 N 0.684 0.416 0.42886291518 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.88E-05 0 0
S/R 32066 Ig-153 50 rs747323263 0.7544 -0.038 0.997 N 0.684 0.416 0.42886291518 gnomAD-4.0.0 6.81722E-06 None None None None N None 0 0 None 0 0 None 0 0 9.32421E-06 0 0
K/E 32360 Ig-154 54 None 0.1605 None 0.996 N 0.625 0.44 0.376921832658 gnomAD-4.0.0 6.842E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99467E-07 0 0
K/Q 32360 Ig-154 54 rs751750046 0.132 0.313 0.999 N 0.716 0.331 0.277730125212 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
K/Q 32360 Ig-154 54 rs751750046 0.132 0.313 0.999 N 0.716 0.331 0.277730125212 gnomAD-4.0.0 2.0526E-06 None None None None N None 0 0 None 0 0 None 0 3.46861E-04 8.99467E-07 0 0
T/I 32756 Ig-155 49 rs199805060 0.18 0.077 0.966 N 0.404 0.272 None gnomAD-2.1.1 4.53225E-04 None None None None N None 4.79497E-03 1.98098E-04 None 0 0 None 9.8E-05 None 0 7.81E-06 0
T/I 32756 Ig-155 49 rs199805060 0.18 0.077 0.966 N 0.404 0.272 None gnomAD-3.1.2 1.34741E-03 None None None None N None 4.7295E-03 4.58655E-04 0 0 0 None 0 0 2.94E-05 0 0
T/I 32756 Ig-155 49 rs199805060 0.18 0.077 0.966 N 0.404 0.272 None 1000 genomes 9.98403E-04 None None None None N None 3.8E-03 0 None None 0 0 None None None 0 None
T/I 32756 Ig-155 49 rs199805060 0.18 0.077 0.966 N 0.404 0.272 None gnomAD-4.0.0 2.44759E-04 None None None None N None 4.59779E-03 2.66676E-04 None 0 0 None 0 0 3.39048E-06 5.48908E-05 4.00115E-04
T/P 32756 Ig-155 49 None 0.3827 None 0.891 N 0.413 0.263 0.38225645794 gnomAD-4.0.0 4.80129E-06 None None None None N None 0 0 None 0 0 None 0 0 5.25001E-06 0 0
R/C 33154 Ig-156 54 rs143556947 0.5929 -0.652 1.0 N 0.711 0.486 None gnomAD-2.1.1 3.21E-05 None None None None N None 1.65385E-04 0 None 0 0 None 0 None 4E-05 3.12E-05 0
R/C 33154 Ig-156 54 rs143556947 0.5929 -0.652 1.0 N 0.711 0.486 None gnomAD-3.1.2 9.21E-05 None None None None N None 1.93171E-04 6.55E-05 0 0 0 None 0 0 7.35E-05 0 0
R/C 33154 Ig-156 54 rs143556947 0.5929 -0.652 1.0 N 0.711 0.486 None 1000 genomes 5.99042E-04 None None None None N None 0 0 None None 0 3E-03 None None None 0 None
R/C 33154 Ig-156 54 rs143556947 0.5929 -0.652 1.0 N 0.711 0.486 None gnomAD-4.0.0 2.23089E-05 None None None None N None 1.73347E-04 1.667E-05 None 0 2.22846E-05 None 1.56323E-05 0 1.52573E-05 1.09803E-05 1.60051E-05
R/G 33154 Ig-156 54 rs143556947 0.7605 -1.266 1.0 N 0.691 0.422 0.673759014288 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
R/G 33154 Ig-156 54 rs143556947 0.7605 -1.266 1.0 N 0.691 0.422 0.673759014288 gnomAD-4.0.0 4.10532E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39684E-06 0 0
R/H 33154 Ig-156 54 rs753958605 0.328 -1.4 1.0 N 0.737 0.378 0.384252928164 gnomAD-2.1.1 2.01E-05 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 3.54E-05 0
R/H 33154 Ig-156 54 rs753958605 0.328 -1.4 1.0 N 0.737 0.378 0.384252928164 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/H 33154 Ig-156 54 rs753958605 0.328 -1.4 1.0 N 0.737 0.378 0.384252928164 gnomAD-4.0.0 6.19728E-06 None None None None N None 0 0 None 0 0 None 0 0 7.62862E-06 0 1.60123E-05
H/R 33250 Ig-157 48 rs1395830573 0.2281 -1.039 0.465 N 0.319 0.178 0.225215365344 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.6E-05 None 0 None 0 0 0
H/R 33250 Ig-157 48 rs1395830573 0.2281 -1.039 0.465 N 0.319 0.178 0.225215365344 gnomAD-4.0.0 3.18457E-06 None None None None N None 0 0 None 0 2.77701E-05 None 0 0 0 1.4339E-05 0
G/E 34190 Ig-160 54 rs1690354224 0.6154 None 1.0 N 0.815 0.564 0.735684033563 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
G/E 34190 Ig-160 54 rs1690354224 0.6154 None 1.0 N 0.815 0.564 0.735684033563 gnomAD-4.0.0 3.84243E-06 None None None None N None 0 3.38926E-05 None 0 0 None 0 0 0 0 2.84349E-05
G/A 34314 Ig-161 57 None 0.7512 None 0.991 N 0.674 0.406 0.115124310173 gnomAD-4.0.0 1.59101E-06 None None None None N None 0 0 None 0 2.77269E-05 None 0 0 0 0 0
G/R 34314 Ig-161 57 rs772007737 0.9576 -0.702 0.999 N 0.843 0.434 0.386395597597 gnomAD-2.1.1 8.04E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 4.65E-05 0 0
G/V 34314 Ig-161 57 None 0.915 None 0.999 N 0.835 0.463 0.466230903105 gnomAD-4.0.0 1.59101E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02352E-05
D/A 34417 Ig-162 55 rs1171155874 0.896 -0.554 1.0 N 0.737 0.589 0.490771696789 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
D/A 34417 Ig-162 55 rs1171155874 0.896 -0.554 1.0 N 0.737 0.589 0.490771696789 gnomAD-4.0.0 1.59179E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85768E-06 0 0
D/N 34417 Ig-162 55 rs1394761197 0.6621 -0.97 1.0 N 0.699 0.431 0.383760037723 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.56E-05 None 0 None 0 0 0
D/Y 34417 Ig-162 55 rs1394761197 0.9012 0.051 1.0 N 0.722 0.62 None gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
D/Y 34417 Ig-162 55 rs1394761197 0.9012 0.051 1.0 N 0.722 0.62 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/Y 34417 Ig-162 55 rs1394761197 0.9012 0.051 1.0 N 0.722 0.62 None gnomAD-4.0.0 3.84465E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17786E-06 0 0
Y/C 35182 Ig-164 54 rs878913505 0.8195 None 1.0 N 0.694 0.582 None gnomAD-4.0.0 2.73654E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59756E-06 0 0
Y/H 35182 Ig-164 54 rs886042549 0.8209 None 0.999 D 0.643 0.562 0.481988042695 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
G/A 35340 Ig-165 55 rs1688680351 0.503 None 0.992 N 0.64 0.3 0.194818534648 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/A 35340 Ig-165 55 rs1688680351 0.503 None 0.992 N 0.64 0.3 0.194818534648 gnomAD-4.0.0 1.23925E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69506E-06 0 0
G/D 35340 Ig-165 55 None 0.5859 None 0.467 N 0.502 0.326 0.170165803431 gnomAD-4.0.0 1.36827E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79879E-06 0 0
G/S 35340 Ig-165 55 rs373610666 0.2552 -0.836 0.998 N 0.778 0.303 0.199424873507 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
G/S 35340 Ig-165 55 rs373610666 0.2552 -0.836 0.998 N 0.778 0.303 0.199424873507 gnomAD-4.0.0 2.0524E-06 None None None None N None 0 0 None 0 0 None 0 3.46741E-04 8.99391E-07 0 0
G/R 35473 Ig-166 54 rs768859424 0.2363 -0.662 0.487 N 0.825 0.39 0.582009938455 gnomAD-2.1.1 8.12E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
G/R 35473 Ig-166 54 rs768859424 0.2363 -0.662 0.487 N 0.825 0.39 0.582009938455 gnomAD-3.1.2 1.97E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 2.94E-05 0 0
G/R 35473 Ig-166 54 rs768859424 0.2363 -0.662 0.487 N 0.825 0.39 0.582009938455 gnomAD-4.0.0 1.97174E-05 None None None None N None 2.41371E-05 0 None 0 0 None 0 0 2.94023E-05 0 0
S/N 35658 Ig-167 52 rs772898540 0.1104 -0.032 0.001 N 0.135 0.059 0.0954503805726 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
S/N 35658 Ig-167 52 rs772898540 0.1104 -0.032 0.001 N 0.135 0.059 0.0954503805726 gnomAD-4.0.0 2.05438E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70073E-06 0 0
N/D 35755 Ig-168 54 None 0.1793 None 0.324 N 0.363 0.23 0.194818534648 gnomAD-4.0.0 1.59103E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02371E-05
N/K 35755 Ig-168 54 rs1687468983 0.427 None 0.193 N 0.343 0.153 0.0138822411134 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/K 35755 Ig-168 54 rs1687468983 0.427 None 0.193 N 0.343 0.153 0.0138822411134 gnomAD-4.0.0 6.56978E-06 None None None None N None 2.41243E-05 0 None 0 0 None 0 0 0 0 0
N/S 35755 Ig-168 54 None 0.1245 None 0.001 N 0.141 0.145 0.134241683229 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.