Structural position:

  • Domain Type: Ig
  • Aligned Position: 14
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand A'

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
V/M 16 Ig-1 11 rs756212082 0.1888 -0.29 1.0 N 0.631 0.334 None gnomAD-2.1.1 2.12E-05 None None None 0.059(TCAP) N None 0 0 None 0 0 None 3.27E-05 None 0 3.1E-05 1.38696E-04
V/M 16 Ig-1 11 rs756212082 0.1888 -0.29 1.0 N 0.631 0.334 None gnomAD-3.1.2 1.97E-05 None None None 0.059(TCAP) N None 0 0 0 0 0 None 0 0 4.41E-05 0 0
V/M 16 Ig-1 11 rs756212082 0.1888 -0.29 1.0 N 0.631 0.334 None gnomAD-4.0.0 2.04472E-05 None None None 0.059(TCAP) N None 0 0 None 0 0 None 0 0 2.54245E-05 1.09818E-05 3.20154E-05
T/I 114 Ig-2 11 rs750606005 0.3821 None 1.0 N 0.7 0.51 0.65257939742 gnomAD-3.1.2 6.57E-06 None None None -0.162(TCAP) N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/I 114 Ig-2 11 rs750606005 0.3821 None 1.0 N 0.7 0.51 0.65257939742 gnomAD-4.0.0 6.57073E-06 None None None -0.162(TCAP) N None 0 0 None 0 0 None 0 0 1.46985E-05 0 0
T/N 114 Ig-2 11 rs750606005 0.3382 -0.382 0.996 D 0.679 0.351 0.578813787709 gnomAD-2.1.1 1.07E-05 None None None -0.392(TCAP) N None 0 0 None 0 1.00311E-04 None 0 None 0 7.82E-06 0
T/N 114 Ig-2 11 rs750606005 0.3382 -0.382 0.996 D 0.679 0.351 0.578813787709 gnomAD-3.1.2 6.57E-06 None None None -0.392(TCAP) N None 0 0 0 0 1.92678E-04 None 0 0 0 0 0
T/N 114 Ig-2 11 rs750606005 0.3382 -0.382 0.996 D 0.679 0.351 0.578813787709 gnomAD-4.0.0 2.56822E-06 None None None -0.392(TCAP) N None 0 0 None 0 4.8506E-05 None 0 0 0 0 0
T/A 953 Ig-3 11 None 0.2353 None 0.977 N 0.421 0.432 0.317958651998 gnomAD-4.0.0 2.05228E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69796E-06 0 0
T/P 953 Ig-3 11 None 0.6571 None 0.999 N 0.615 0.662 0.592512737887 gnomAD-4.0.0 1.77864E-05 None None None None N None 0 0 None 0 0 None 0 0 2.33823E-05 0 0
T/S 953 Ig-3 11 rs72647865 0.2897 -0.223 0.989 N 0.453 0.357 0.294918367191 gnomAD-2.1.1 4E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
T/S 953 Ig-3 11 rs72647865 0.2897 -0.223 0.989 N 0.453 0.357 0.294918367191 gnomAD-4.0.0 6.84097E-06 None None None None N None 0 0 None 0 0 None 1.8721E-05 0 6.29527E-06 1.15931E-05 1.6559E-05
R/G 1301 Ig-5 11 None 0.8514 None 0.939 N 0.543 0.471 0.5452609689 gnomAD-4.0.0 1.59113E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85739E-06 0 0
R/K 1301 Ig-5 11 None 0.2842 None 0.76 N 0.583 0.247 0.260249123532 gnomAD-4.0.0 1.20069E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31292E-06 0 0
N/D 1566 Ig-7 11 None 0.2397 None 0.425 N 0.261 0.291 0.302793454619 gnomAD-4.0.0 1.59081E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85682E-06 0 0
R/K 1713 Ig-8 11 rs890589931 0.2506 None 0.997 N 0.569 0.375 0.311387274539 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/K 1713 Ig-8 11 rs890589931 0.2506 None 0.997 N 0.569 0.375 0.311387274539 gnomAD-4.0.0 1.92076E-05 None None None None I None 0 0 None 0 0 None 0 0 2.54233E-05 0 1.60046E-05
R/T 1851 Ig-9 11 None 0.4059 None 1.0 N 0.711 0.516 0.453772157364 gnomAD-4.0.0 9.60257E-06 None None None None N None 0 0 None 0 0 None 0 0 1.05E-05 0 0
V/A 2184 Ig-11 11 None 0.1106 None None N 0.069 0.136 0.302793454619 gnomAD-4.0.0 1.59088E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
E/Q 2277 Ig-12 11 rs373469418 0.2205 -0.157 1.0 N 0.607 0.403 None gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.65E-05 0
E/Q 2277 Ig-12 11 rs373469418 0.2205 -0.157 1.0 N 0.607 0.403 None gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
E/Q 2277 Ig-12 11 rs373469418 0.2205 -0.157 1.0 N 0.607 0.403 None gnomAD-4.0.0 2.04532E-05 None None None None N None 0 0 None 0 0 None 0 0 2.71199E-05 0 1.60046E-05
N/D 2455 Ig-14 11 None 0.0982 None None N 0.183 0.142 0.215109475489 gnomAD-4.0.0 1.36822E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79864E-06 0 0
N/H 2455 Ig-14 11 rs1561255734 0.0689 None None N 0.183 0.134 0.20549828249 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
N/H 2455 Ig-14 11 rs1561255734 0.0689 None None N 0.183 0.134 0.20549828249 gnomAD-4.0.0 6.84111E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99321E-07 0 0
N/S 2455 Ig-14 11 rs2091854692 0.0696 None None N 0.157 0.072 0.101711395817 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
N/S 2455 Ig-14 11 rs2091854692 0.0696 None None N 0.157 0.072 0.101711395817 gnomAD-4.0.0 3.84202E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17576E-06 0 0
T/I 2543 Ig-15 11 rs765136135 0.1576 -0.061 0.852 N 0.339 0.405 0.468420198123 gnomAD-2.1.1 1.07E-05 None None None None N None 1.22289E-04 0 None 0 0 None 0 None 0 0 0
T/I 2543 Ig-15 11 rs765136135 0.1576 -0.061 0.852 N 0.339 0.405 0.468420198123 gnomAD-3.1.2 3.94E-05 None None None None N None 1.20761E-04 6.55E-05 0 0 0 None 0 0 0 0 0
T/I 2543 Ig-15 11 rs765136135 0.1576 -0.061 0.852 N 0.339 0.405 0.468420198123 gnomAD-4.0.0 6.19647E-06 None None None None N None 1.20196E-04 1.66739E-05 None 0 0 None 0 0 0 0 0
T/N 2543 Ig-15 11 None 0.1287 None 0.976 D 0.356 0.313 0.461495907335 gnomAD-4.0.0 3.42066E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49659E-06 0 0
T/S 2543 Ig-15 11 rs765136135 0.12 -0.649 0.31 N 0.171 0.238 0.277317399466 gnomAD-2.1.1 2.84E-05 None None None None N None 3.26105E-04 0 None 0 0 None 0 None 0 0 0
T/S 2543 Ig-15 11 rs765136135 0.12 -0.649 0.31 N 0.171 0.238 0.277317399466 gnomAD-3.1.2 8.55E-05 None None None None N None 3.13979E-04 0 0 0 0 None 0 0 0 0 0
T/S 2543 Ig-15 11 rs765136135 0.12 -0.649 0.31 N 0.171 0.238 0.277317399466 gnomAD-4.0.0 4.77248E-06 None None None None N None 0 2.28707E-05 None 0 0 None 0 0 5.71337E-06 0 0
T/S 2630 Ig-16 10 rs2091468969 0.1828 None 0.374 N 0.319 0.211 0.251116650651 gnomAD-4.0.0 1.59105E-06 None None None None N None 0 0 None 0 0 None 0 2.41429E-04 0 0 0
T/A 2717 Ig-17 11 rs1478991790 0.2092 None 0.999 D 0.548 0.475 0.352693368174 gnomAD-4.0.0 1.59148E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85657E-06 0 0
T/K 2717 Ig-17 11 rs781565875 0.5258 -0.216 1.0 D 0.693 0.486 0.566666267248 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.81E-06 0
E/K 2892 Ig-19 11 rs763393324 0.1184 0.367 0.742 N 0.575 0.122 0.345175991111 gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.65E-05 0
E/K 2892 Ig-19 11 rs763393324 0.1184 0.367 0.742 N 0.575 0.122 0.345175991111 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/K 2892 Ig-19 11 rs763393324 0.1184 0.367 0.742 N 0.575 0.122 0.345175991111 gnomAD-4.0.0 1.30129E-05 None None None None N None 0 0 None 0 0 None 0 0 1.69493E-05 0 1.60041E-05
E/Q 2892 Ig-19 11 rs763393324 0.1126 -0.045 0.008 N 0.228 0.107 0.252681307341 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.63559E-04
E/Q 2892 Ig-19 11 rs763393324 0.1126 -0.045 0.008 N 0.228 0.107 0.252681307341 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
E/Q 2892 Ig-19 11 rs763393324 0.1126 -0.045 0.008 N 0.228 0.107 0.252681307341 gnomAD-4.0.0 1.23933E-06 None None None None N None 1.33601E-05 0 None 0 0 None 0 0 8.47463E-07 0 0
N/S 2979 Ig-20 11 rs765890815 0.114 0.183 0.996 N 0.418 0.364 0.290590437066 gnomAD-2.1.1 7.97E-06 None None None None N None 0 0 None 0 0 None 6.53E-05 None 0 0 0
N/S 2979 Ig-20 11 rs765890815 0.114 0.183 0.996 N 0.418 0.364 0.290590437066 gnomAD-4.0.0 3.18176E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86549E-05 0
K/N 3068 Ig-21 11 rs772683836 0.8234 0.002 1.0 N 0.737 0.291 0.225902525712 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
K/N 3068 Ig-21 11 rs772683836 0.8234 0.002 1.0 N 0.737 0.291 0.225902525712 gnomAD-4.0.0 6.84102E-07 None None None None N None 0 2.23664E-05 None 0 0 None 0 0 0 0 0
Q/R 3157 Ig-22 11 None 0.138 None 0.801 N 0.342 0.213 0.265929055128 gnomAD-4.0.0 2.05251E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79862E-06 1.15934E-05 0
T/A 3249 Ig-23 11 rs2090055572 0.0889 None 0.122 N 0.119 0.18 0.223146558224 gnomAD-4.0.0 2.73689E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59744E-06 0 0
V/F 3355 Ig-24 11 None 0.1547 None 0.317 N 0.345 0.13 0.490352026379 gnomAD-4.0.0 6.8409E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99321E-07 0 0
V/I 3355 Ig-24 11 None 0.0798 None None N 0.121 0.081 0.162503812791 gnomAD-4.0.0 6.8409E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99321E-07 0 0
V/L 3355 Ig-24 11 None 0.1719 None None N 0.093 0.085 0.132336055621 gnomAD-4.0.0 6.8409E-07 None None None None N None 0 2.23614E-05 None 0 0 None 0 0 0 0 0
R/K 3475 Ig-25 11 None 0.1458 None None None None 0.151 None gnomAD-4.0.0 1.59276E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86154E-06 0 0
T/P 3670 Ig-26 11 rs794729589 0.1803 None None None None 0.09 None gnomAD-4.0.0 7.52639E-06 None None None None I None 0 0 None 0 0 None 0 0 9.89406E-06 0 0
T/S 3670 Ig-26 11 rs794729589 0.1222 -0.019 None None None 0.125 None gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
T/S 3670 Ig-26 11 rs794729589 0.1222 -0.019 None None None 0.125 None gnomAD-4.0.0 6.84217E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65651E-05
R/C 3948 Ig-28 11 rs397517827 0.0748 -0.08 0.964 D 0.347 0.215 None gnomAD-2.1.1 2.05215E-04 None None None None I None 1.29199E-04 2.9E-05 None 0 7.2367E-04 None 1.04575E-03 None 0 2.67E-05 0
R/C 3948 Ig-28 11 rs397517827 0.0748 -0.08 0.964 D 0.347 0.215 None gnomAD-3.1.2 1.18314E-04 None None None None I None 2.41E-05 0 0 0 9.65624E-04 None 0 0 1.47E-05 2.27838E-03 0
R/C 3948 Ig-28 11 rs397517827 0.0748 -0.08 0.964 D 0.347 0.215 None gnomAD-4.0.0 1.31981E-04 None None None None I None 5.33063E-05 0 None 0 4.45812E-04 None 0 1.64962E-04 3.89887E-05 1.4713E-03 1.28053E-04
R/G 3948 Ig-28 11 None 0.1452 None 0.13 D 0.444 0.175 None gnomAD-4.0.0 6.84175E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99429E-07 0 0
R/H 3948 Ig-28 11 rs775618077 0.0633 -0.537 None N 0.209 0.067 None gnomAD-2.1.1 3.93E-05 None None None None I None 0 2.83E-05 None 0 0 None 0 None 1.99888E-04 3.13E-05 1.4041E-04
R/H 3948 Ig-28 11 rs775618077 0.0633 -0.537 None N 0.209 0.067 None gnomAD-3.1.2 2.63E-05 None None None None I None 0 1.31044E-04 0 0 0 None 9.44E-05 0 1.47E-05 0 0
R/H 3948 Ig-28 11 rs775618077 0.0633 -0.537 None N 0.209 0.067 None gnomAD-4.0.0 1.98304E-05 None None None None I None 0 8.33583E-05 None 0 2.22826E-05 None 1.40647E-04 0 1.35614E-05 0 1.60128E-05
R/L 3948 Ig-28 11 rs775618077 0.1186 None None N 0.253 0.091 None gnomAD-4.0.0 4.10505E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39659E-06 0 0
V/I 4616 Ig-29 11 rs1008595479 0.0605 None None N 0.082 0.118 None gnomAD-4.0.0 1.59114E-06 None None None None N None 0 2.28655E-05 None 0 0 None 0 0 0 0 0
V/L 4616 Ig-29 11 rs1008595479 0.1057 -0.117 0.002 N 0.14 0.112 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
V/L 4616 Ig-29 11 rs1008595479 0.1057 -0.117 0.002 N 0.14 0.112 None gnomAD-4.0.0 1.59114E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85801E-06 0 0
T/I 4805 Ig-31 11 rs2081384846 0.3245 None 0.997 N 0.527 0.373 0.458554320643 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/I 4805 Ig-31 11 rs2081384846 0.3245 None 0.997 N 0.527 0.373 0.458554320643 gnomAD-4.0.0 6.57047E-06 None None None None I None 2.41208E-05 0 None 0 0 None 0 0 0 0 0
T/K 4805 Ig-31 11 None 0.3617 None 0.576 N 0.281 0.252 0.377274123778 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/P 4805 Ig-31 11 rs1176268416 0.2611 -0.105 0.997 N 0.527 0.4 0.414150184683 gnomAD-2.1.1 8.15E-06 None None None None I None 0 5.86E-05 None 0 0 None 0 None 0 0 0
T/P 4805 Ig-31 11 rs1176268416 0.2611 -0.105 0.997 N 0.527 0.4 0.414150184683 gnomAD-4.0.0 3.202E-06 None None None None I None 0 4.6032E-05 None 0 0 None 0 0 0 0 0
Q/L 4898 Ig-32 11 None 0.1421 None 0.425 N 0.29 0.255 0.505028829284 gnomAD-4.0.0 1.59143E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85814E-06 0 0
Q/R 4898 Ig-32 11 rs763540495 0.1232 0.602 0.006 N 0.169 0.162 0.18274738541 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
Q/R 4898 Ig-32 11 rs763540495 0.1232 0.602 0.006 N 0.169 0.162 0.18274738541 gnomAD-4.0.0 1.59143E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
D/G 5085 Ig-34 11 None 0.2272 None 0.324 N 0.346 0.293 0.253205268125 gnomAD-4.0.0 1.3937E-06 None None None None I None 0 0 None 0 0 None 0 0 1.82085E-06 0 0
D/N 5085 Ig-34 11 rs374299783 0.1001 0.406 0.324 N 0.342 0.108 None gnomAD-2.1.1 8.76E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.9E-05 0
D/N 5085 Ig-34 11 rs374299783 0.1001 0.406 0.324 N 0.342 0.108 None gnomAD-3.1.2 4.6E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 8.82E-05 0 0
D/N 5085 Ig-34 11 rs374299783 0.1001 0.406 0.324 N 0.342 0.108 None gnomAD-4.0.0 5.29193E-05 None None None None I None 1.35168E-05 0 None 0 0 None 0 0 6.94455E-05 0 3.26115E-05
Q/R 5271 Ig-36 11 rs1578198392 0.1132 None 0.642 N 0.346 0.222 0.223146558224 gnomAD-4.0.0 1.20036E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31255E-06 0 0
D/A 5367 Ig-37 11 rs751854907 0.127 0.061 0.001 N 0.315 0.217 0.288727942641 gnomAD-2.1.1 4.08E-06 None None None None I None 0 2.95E-05 None 0 0 None 0 None 0 0 0
D/A 5367 Ig-37 11 rs751854907 0.127 0.061 0.001 N 0.315 0.217 0.288727942641 gnomAD-4.0.0 1.37336E-06 None None None None I None 0 2.25611E-05 None 0 0 None 0 0 9.02037E-07 0 0
D/G 5367 Ig-37 11 rs751854907 0.1506 -0.129 0.124 N 0.461 0.226 0.193865811164 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
D/G 5367 Ig-37 11 rs751854907 0.1506 -0.129 0.124 N 0.461 0.226 0.193865811164 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
D/G 5367 Ig-37 11 rs751854907 0.1506 -0.129 0.124 N 0.461 0.226 0.193865811164 gnomAD-4.0.0 3.10859E-06 None None None None I None 0 0 None 0 0 None 0 0 4.24939E-06 0 0
D/N 5367 Ig-37 11 None 0.0785 None 0.002 N 0.254 0.202 0.211220785272 gnomAD-4.0.0 1.60627E-06 None None None None I None 0 0 None 0 0 None 0 0 2.88722E-06 0 0
D/Y 5367 Ig-37 11 rs1438312782 0.1681 0.297 0.667 N 0.643 0.345 0.640272089493 gnomAD-2.1.1 4.1E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.03E-06 0
D/Y 5367 Ig-37 11 rs1438312782 0.1681 0.297 0.667 N 0.643 0.345 0.640272089493 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
D/Y 5367 Ig-37 11 rs1438312782 0.1681 0.297 0.667 N 0.643 0.345 0.640272089493 gnomAD-4.0.0 3.87239E-06 None None None None I None 0 0 None 0 0 None 0 0 7.23966E-06 0 0
D/G 5460 Ig-38 11 None 0.1858 None 0.477 N 0.497 0.314 0.289474373501 gnomAD-4.0.0 1.62005E-06 None None None None I None 0 0 None 0 0 None 0 0 2.9025E-06 0 0
D/N 5460 Ig-38 11 rs771075704 0.1031 -0.023 0.864 N 0.513 0.289 0.331619326243 gnomAD-2.1.1 4.2E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.19E-06 0
D/N 5460 Ig-38 11 rs771075704 0.1031 -0.023 0.864 N 0.513 0.289 0.331619326243 gnomAD-4.0.0 1.62156E-06 None None None None I None 0 0 None 0 0 None 0 0 2.905E-06 0 0
S/T 5740 Ig-41 11 rs779492952 0.0766 0.281 0.134 N 0.092 0.185 0.144782658237 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.98E-06 0
S/T 5740 Ig-41 11 rs779492952 0.0766 0.281 0.134 N 0.092 0.185 0.144782658237 gnomAD-4.0.0 6.39799E-06 None None None None I None 0 0 None 0 0 None 0 0 1.14952E-05 0 0
D/G 5833 Ig-42 11 rs1340894070 0.387 -0.295 0.91 D 0.512 0.269 0.299086750705 gnomAD-2.1.1 8.04E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
D/G 5833 Ig-42 11 rs1340894070 0.387 -0.295 0.91 D 0.512 0.269 0.299086750705 gnomAD-3.1.2 8.55E-05 None None None None N None 0 8.51677E-04 0 0 0 None 0 0 0 0 0
D/G 5833 Ig-42 11 rs1340894070 0.387 -0.295 0.91 D 0.512 0.269 0.299086750705 gnomAD-4.0.0 1.92212E-05 None None None None N None 0 2.5428E-04 None 0 0 None 0 0 0 0 0
D/N 5929 Ig-43 11 None 0.1782 None 0.989 N 0.464 0.28 0.32306181527 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
D/N 6022 Ig-44 11 rs767465221 0.1177 0.173 0.046 N 0.131 0.166 0.215109475489 gnomAD-2.1.1 4.14E-06 None None None None N None 0 0 None 0 0 None 0 None 4.69E-05 0 0
D/N 6022 Ig-44 11 rs767465221 0.1177 0.173 0.046 N 0.131 0.166 0.215109475489 gnomAD-4.0.0 1.60502E-06 None None None None N None 0 0 None 0 0 None 1.88736E-05 0 0 0 0
L/F 6115 Ig-45 11 rs771329302 0.0921 None 0.317 N 0.61 0.129 0.460795861206 gnomAD-4.0.0 2.73784E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59839E-06 0 0
E/K 6209 Ig-46 11 rs751253663 0.2981 0.711 0.998 N 0.583 0.404 0.527356302626 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
E/K 6209 Ig-46 11 rs751253663 0.2981 0.711 0.998 N 0.583 0.404 0.527356302626 gnomAD-4.0.0 1.59212E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43328E-05 0
E/Q 6209 Ig-46 11 rs751253663 0.2127 0.25 0.999 D 0.675 0.355 0.419713421852 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
E/Q 6209 Ig-46 11 rs751253663 0.2127 0.25 0.999 D 0.675 0.355 0.419713421852 gnomAD-4.0.0 1.59212E-06 None None None None N None 0 2.28749E-05 None 0 0 None 0 0 0 0 0
T/I 6302 Ig-47 11 None 0.1517 None 0.473 D 0.287 0.124 0.404034981753 gnomAD-4.0.0 6.90047E-07 None None None None N None 0 0 None 0 0 None 0 0 9.04143E-07 0 0
T/N 6302 Ig-47 11 rs766831279 0.1425 -0.027 0.642 N 0.18 0.13 0.380052290102 gnomAD-2.1.1 1.13E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.46E-05 0
T/N 6302 Ig-47 11 rs766831279 0.1425 -0.027 0.642 N 0.18 0.13 0.380052290102 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
T/N 6302 Ig-47 11 rs766831279 0.1425 -0.027 0.642 N 0.18 0.13 0.380052290102 gnomAD-4.0.0 3.12243E-06 None None None None N None 0 3.42654E-05 None 0 0 None 0 0 2.5553E-06 0 0
D/G 6395 Ig-48 11 None 0.3291 None 0.27 N 0.323 0.172 0.225902525712 gnomAD-4.0.0 6.87558E-07 None None None None N None 0 0 None 0 0 None 0 0 9.04225E-07 0 0
D/G 6491 Ig-49 11 rs747741123 0.2243 -0.229 0.722 N 0.422 0.315 0.287603790349 gnomAD-2.1.1 8.39E-06 None None None None N None 0 3.03E-05 None 0 0 None 3.49E-05 None 0 0 0
D/G 6491 Ig-49 11 rs747741123 0.2243 -0.229 0.722 N 0.422 0.315 0.287603790349 gnomAD-4.0.0 2.06356E-06 None None None None N None 0 2.30319E-05 None 0 0 None 0 0 0 1.18164E-05 1.66706E-05
D/N 6491 Ig-49 11 rs2079733131 0.1356 None 0.722 N 0.484 0.254 0.21279746466 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07297E-04 0
D/N 6491 Ig-49 11 rs2079733131 0.1356 None 0.722 N 0.484 0.254 0.21279746466 gnomAD-4.0.0 6.5754E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07297E-04 0
D/Y 6491 Ig-49 11 None 0.3742 None 0.983 N 0.555 0.349 0.632792546795 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Q/K 6584 Ig-50 11 rs908969278 0.102 None 0.002 N 0.151 0.106 None gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
E/Q 6771 Ig-52 11 rs750614578 0.1752 0.023 0.385 N 0.472 0.257 0.272639205421 gnomAD-2.1.1 8.75E-06 None None None None N None 0 0 None 1.11185E-04 0 None 0 None 0 9.46E-06 0
E/Q 6771 Ig-52 11 rs750614578 0.1752 0.023 0.385 N 0.472 0.257 0.272639205421 gnomAD-4.0.0 2.81713E-06 None None None None N None 0 0 None 1.20715E-04 0 None 0 0 9.18771E-07 0 0
T/A 6958 Ig-54 11 None 0.072 None 0.139 N 0.185 0.108 0.215869574891 gnomAD-4.0.0 1.60919E-06 None None None None I None 0 0 None 0 0 None 0 0 2.90225E-06 0 0
T/M 6958 Ig-54 11 rs371824963 0.0735 0.112 0.282 N 0.163 0.183 None gnomAD-2.1.1 2.44E-05 None None None None I None 0 0 None 0 1.11794E-04 None 3.32E-05 None 0 2.69E-05 0
T/M 6958 Ig-54 11 rs371824963 0.0735 0.112 0.282 N 0.163 0.183 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/M 6958 Ig-54 11 rs371824963 0.0735 0.112 0.282 N 0.163 0.183 None gnomAD-4.0.0 1.05806E-05 None None None None I None 0 0 None 0 4.47688E-05 None 0 1.65453E-04 1.02167E-05 1.10263E-05 1.60932E-05
E/K 7147 Ig-56 11 None 0.2092 None 0.549 D 0.457 0.295 0.360565625551 gnomAD-4.0.0 3.23355E-06 None None None None I None 0 0 None 0 0 None 0 0 2.89457E-06 0 3.0673E-05
S/F 7240 Ig-57 11 None 0.1256 None 0.096 D 0.399 0.211 0.420939154896 gnomAD-4.0.0 1.59228E-06 None None None None N None 0 2.28781E-05 None 0 0 None 0 0 0 0 0
E/G 7333 Ig-58 11 None 0.1609 None 0.997 N 0.486 0.487 None gnomAD-4.0.0 1.59401E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86248E-06 0 0
E/Q 7333 Ig-58 11 None 0.1024 None 0.999 N 0.479 0.288 0.312608672186 gnomAD-4.0.0 1.59407E-06 None None None None I None 0 0 None 0 2.78056E-05 None 0 0 0 0 0
D/E 7525 Ig-60 11 rs200061856 0.1608 0.148 0.003 N 0.123 0.079 0.220303561663 gnomAD-2.1.1 6.58E-05 None None None None N None 0 2.94E-05 None 0 0 None 6.91E-05 None 0 1.17749E-04 0
D/E 7525 Ig-60 11 rs200061856 0.1608 0.148 0.003 N 0.123 0.079 0.220303561663 gnomAD-3.1.2 4.6E-05 None None None None N None 0 0 1.09649E-03 0 0 None 0 0 8.82E-05 0 0
D/E 7525 Ig-60 11 rs200061856 0.1608 0.148 0.003 N 0.123 0.079 0.220303561663 gnomAD-4.0.0 3.29919E-05 None None None None N None 0 1.67904E-05 None 0 0 None 0 0 3.91229E-05 2.23324E-05 4.82765E-05
D/H 7525 Ig-60 11 None 0.3317 None 0.995 N 0.523 0.345 0.463586170655 gnomAD-4.0.0 2.06407E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70908E-06 0 0
G/R 7712 Ig-62 11 None 0.3439 None 0.801 N 0.434 0.252 0.540518506614 gnomAD-4.0.0 2.06262E-06 None None None None I None 0 0 None 0 2.52551E-05 None 0 0 0 1.18304E-05 1.66617E-05
S/A 7805 Ig-63 11 rs369062299 0.0835 -0.573 None D 0.085 0.172 None gnomAD-2.1.1 4.04E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
S/A 7805 Ig-63 11 rs369062299 0.0835 -0.573 None D 0.085 0.172 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
S/A 7805 Ig-63 11 rs369062299 0.0835 -0.573 None D 0.085 0.172 None gnomAD-4.0.0 2.0299E-06 None None None None N None 3.49455E-05 0 None 0 0 None 0 0 0 0 0
E/G 8088 Ig-66 11 None 0.2786 None 0.669 N 0.492 0.393 0.501371821861 gnomAD-4.0.0 6.85347E-07 None None None None I None 0 0 None 0 0 None 0 0 9.004E-07 0 0
S/G 8181 Ig-67 11 rs753248001 0.1545 -0.461 0.09 D 0.231 0.24 0.227260227426 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
S/G 8181 Ig-67 11 rs753248001 0.1545 -0.461 0.09 D 0.231 0.24 0.227260227426 gnomAD-4.0.0 5.47604E-06 None None None None N None 0 0 None 0 2.52042E-05 None 0 0 1.79961E-06 4.64102E-05 1.65761E-05
S/I 8181 Ig-67 11 rs2077848883 0.1935 None 0.627 D 0.395 0.262 0.550759897685 gnomAD-4.0.0 6.84507E-07 None None None None N None 2.99043E-05 0 None 0 0 None 0 0 0 0 0
S/R 8181 Ig-67 11 rs753248001 0.5153 0.067 0.003 N 0.182 0.178 0.201204373187 gnomAD-2.1.1 8.06E-06 None None None None N None 0 5.81E-05 None 0 0 None 0 None 0 0 0
S/R 8181 Ig-67 11 rs753248001 0.5153 0.067 0.003 N 0.182 0.178 0.201204373187 gnomAD-4.0.0 1.36901E-06 None None None None N None 0 4.47467E-05 None 0 0 None 0 0 0 0 0
E/K 8274 Ig-68 11 rs72648981 0.1874 0.792 0.967 N 0.604 0.248 None gnomAD-2.1.1 2.30508E-03 None None None None I None 4.97471E-04 7.95635E-04 None 1.16822E-03 0 None 0 None 4.02228E-03 3.75627E-03 2.9855E-03
E/K 8274 Ig-68 11 rs72648981 0.1874 0.792 0.967 N 0.604 0.248 None gnomAD-3.1.2 2.32668E-03 None None None None I None 6.75774E-04 1.17878E-03 0 5.76701E-04 0 None 3.9548E-03 0 3.82241E-03 0 1.91022E-03
E/K 8274 Ig-68 11 rs72648981 0.1874 0.792 0.967 N 0.604 0.248 None 1000 genomes 5.99042E-04 None None None None I None 0 0 None None 0 3E-03 None None None 0 None
E/K 8274 Ig-68 11 rs72648981 0.1874 0.792 0.967 N 0.604 0.248 None gnomAD-4.0.0 2.97975E-03 None None None None I None 5.33988E-04 8.52016E-04 None 8.12623E-04 0 None 3.21302E-03 0 3.69014E-03 0 2.16485E-03
H/Q 8370 Ig-69 11 None 0.0713 None None N 0.085 0.166 0.0297737177859 gnomAD-4.0.0 3.42986E-06 None None None None N None 0 0 None 3.84645E-05 0 None 1.88296E-05 0 2.70256E-06 0 0
H/R 8370 Ig-69 11 rs1439210373 0.0661 -0.303 0.007 N 0.212 0.13 0.185906805712 gnomAD-2.1.1 4.09E-06 None None None None N None 0 2.94E-05 None 0 0 None 0 None 0 0 0
H/R 8370 Ig-69 11 rs1439210373 0.0661 -0.303 0.007 N 0.212 0.13 0.185906805712 gnomAD-4.0.0 5.48595E-06 None None None None N None 0 2.25652E-05 None 0 0 None 0 0 6.30456E-06 0 0
D/E 8466 Ig-70 11 rs72648986 0.1665 -0.092 0.001 N 0.111 0.11 0.148003135375 gnomAD-2.1.1 1.10534E-02 None None None None N None 7.56824E-02 4.8409E-03 None 6.58404E-03 1.0248E-04 None 2.19823E-02 None 4E-05 2.30022E-03 7.73994E-03
D/E 8466 Ig-70 11 rs72648986 0.1665 -0.092 0.001 N 0.111 0.11 0.148003135375 gnomAD-3.1.2 2.39604E-02 None None None None N None 7.56903E-02 1.12595E-02 0 7.20046E-03 0 None 0 9.49367E-03 2.07274E-03 2.40664E-02 2.53104E-02
D/E 8466 Ig-70 11 rs72648986 0.1665 -0.092 0.001 N 0.111 0.11 0.148003135375 1000 genomes 2.8754E-02 None None None None N None 8.09E-02 1.01E-02 None None 0 3E-03 None None None 2.76E-02 None
D/E 8466 Ig-70 11 rs72648986 0.1665 -0.092 0.001 N 0.111 0.11 0.148003135375 gnomAD-4.0.0 6.60199E-03 None None None None N None 7.56533E-02 6.89862E-03 None 7.67151E-03 1.78269E-04 None 6.24824E-05 8.25628E-03 1.45907E-03 2.13269E-02 9.81428E-03
D/G 8466 Ig-70 11 rs773229351 0.1775 -0.429 0.053 N 0.327 0.127 0.233150807113 gnomAD-2.1.1 7.15E-06 None None None None N None 4.13E-05 0 None 0 0 None 0 None 0 7.82E-06 0
D/G 8466 Ig-70 11 rs773229351 0.1775 -0.429 0.053 N 0.327 0.127 0.233150807113 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
D/G 8466 Ig-70 11 rs773229351 0.1775 -0.429 0.053 N 0.327 0.127 0.233150807113 gnomAD-4.0.0 5.12636E-06 None None None None N None 3.38295E-05 0 None 0 0 None 0 0 4.789E-06 0 0
D/H 8466 Ig-70 11 rs372994306 0.2571 0.256 0.783 N 0.347 0.183 None gnomAD-2.1.1 2.82E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.23E-05 0
D/H 8466 Ig-70 11 rs372994306 0.2571 0.256 0.783 N 0.347 0.183 None gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
D/H 8466 Ig-70 11 rs372994306 0.2571 0.256 0.783 N 0.347 0.183 None gnomAD-4.0.0 2.29344E-05 None None None None N None 1.33529E-05 0 None 0 0 None 0 0 2.96744E-05 0 1.60159E-05
R/K 8559 Ig-71 11 rs745818225 0.0881 0.088 None N 0.193 0.261 0.382925413656 gnomAD-2.1.1 4.72E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.09E-05 0
R/K 8559 Ig-71 11 rs745818225 0.0881 0.088 None N 0.193 0.261 0.382925413656 gnomAD-4.0.0 2.08309E-06 None None None None I None 0 0 None 0 0 None 0 0 2.72746E-06 0 0
E/D 8653 Ig-72 11 rs879235743 0.1578 -0.246 0.345 N 0.487 0.101 0.277730125212 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
E/D 8653 Ig-72 11 rs879235743 0.1578 -0.246 0.345 N 0.487 0.101 0.277730125212 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/D 8653 Ig-72 11 rs879235743 0.1578 -0.246 0.345 N 0.487 0.101 0.277730125212 gnomAD-4.0.0 2.56592E-06 None None None None I None 0 0 None 0 0 None 0 0 4.79035E-06 0 0
E/G 8653 Ig-72 11 None 0.1669 None 0.979 N 0.499 0.504 0.570754586423 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
E/K 8653 Ig-72 11 None 0.1266 None 0.791 D 0.499 0.275 0.396494342077 gnomAD-4.0.0 1.60023E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86885E-06 0 0
E/Q 8653 Ig-72 11 rs566740788 0.1091 0.151 0.144 D 0.294 0.129 0.272639205421 gnomAD-2.1.1 4.06E-06 None None None None I None 6.48E-05 0 None 0 0 None 0 None 0 0 0
E/Q 8653 Ig-72 11 rs566740788 0.1091 0.151 0.144 D 0.294 0.129 0.272639205421 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
E/Q 8653 Ig-72 11 rs566740788 0.1091 0.151 0.144 D 0.294 0.129 0.272639205421 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
E/Q 8653 Ig-72 11 rs566740788 0.1091 0.151 0.144 D 0.294 0.129 0.272639205421 gnomAD-4.0.0 2.57369E-06 None None None None I None 3.39305E-05 0 None 0 0 None 0 0 0 0 0
S/P 8746 Ig-73 11 None 0.1759 None 0.956 N 0.396 0.414 0.362758974969 gnomAD-4.0.0 1.59661E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43724E-05 0
K/Q 8840 Ig-74 11 None 0.0861 None 0.001 N 0.195 0.108 0.0482279557977 gnomAD-4.0.0 1.59287E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86056E-06 0 0
K/T 8840 Ig-74 11 rs2077106214 0.0611 None None N 0.103 0.118 0.0716867268079 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
K/T 8840 Ig-74 11 rs2077106214 0.0611 None None N 0.103 0.118 0.0716867268079 gnomAD-4.0.0 6.57013E-06 None None None None N None 2.41185E-05 0 None 0 0 None 0 0 0 0 0
D/G 9029 Ig-76 11 rs1336740450 0.1823 -0.051 0.669 N 0.343 0.337 0.265010934533 gnomAD-2.1.1 6.37E-05 None None None None N None 2.29621E-04 0 None 0 0 None 0 None 0 0 0
D/G 9029 Ig-76 11 rs1336740450 0.1823 -0.051 0.669 N 0.343 0.337 0.265010934533 gnomAD-3.1.2 1.97E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 2.07211E-04 0
D/G 9029 Ig-76 11 rs1336740450 0.1823 -0.051 0.669 N 0.343 0.337 0.265010934533 gnomAD-4.0.0 4.05966E-06 None None None None N None 5.24054E-05 0 None 0 0 None 0 0 0 4.69792E-05 0
S/G 9122 Ig-77 11 rs2076813561 0.1043 None 0.454 N 0.311 0.286 0.225902525712 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
K/N 9215 Ig-78 11 rs768260006 0.1827 None 0.642 N 0.212 0.153 0.17948927462 gnomAD-4.0.0 2.05274E-06 None None None None I None 5.9755E-05 0 None 0 0 None 0 0 8.99523E-07 0 0
K/T 9215 Ig-78 11 None 0.0746 None 0.642 N 0.292 0.237 0.314417295294 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
E/G 9504 Ig-81 12 None 0.4076 None 0.998 None 0.598 0.46 0.544082543865 gnomAD-4.0.0 1.59189E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43295E-05 0
T/I 9600 Ig-82 11 None 0.1797 None 0.901 None 0.499 0.338 0.527356302626 gnomAD-4.0.0 1.59213E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86041E-06 0 0
R/G 9708 Ig-83 11 rs1274452311 0.5855 None 0.642 None 0.468 0.256 0.466059976078 gnomAD-4.0.0 3.42508E-06 None None None None I None 0 0 None 0 0 None 0 0 4.50058E-06 0 0
R/K 9708 Ig-83 11 None 0.1267 None 0.002 None 0.226 0.153 0.311387274539 gnomAD-4.0.0 6.84982E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65854E-05
R/T 9708 Ig-83 11 rs969965309 0.3326 0.136 0.023 None 0.298 0.223 0.286848849266 gnomAD-2.1.1 4.07E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.01E-06 0
R/T 9708 Ig-83 11 rs969965309 0.3326 0.136 0.023 None 0.298 0.223 0.286848849266 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/T 9708 Ig-83 11 rs969965309 0.3326 0.136 0.023 None 0.298 0.223 0.286848849266 gnomAD-4.0.0 2.48124E-06 None None None None I None 0 0 None 0 0 None 0 0 3.39264E-06 0 0
T/R 9910 Ig-84 11 None 0.6063 None 0.959 None 0.394 0.347 0.480198768302 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/A 9999 Ig-85 11 rs776483588 0.1083 -0.416 0.001 None 0.09 0.078 0.154104182512 gnomAD-2.1.1 4.01E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
T/A 9999 Ig-85 11 rs776483588 0.1083 -0.416 0.001 None 0.09 0.078 0.154104182512 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
T/A 9999 Ig-85 11 rs776483588 0.1083 -0.416 0.001 None 0.09 0.078 0.154104182512 gnomAD-4.0.0 3.84321E-06 None None None None N None 5.07237E-05 0 None 0 0 None 0 0 0 0 0
V/A 10088 Ig-86 11 None 0.8302 None 0.953 None 0.493 0.205 0.65701131685 gnomAD-4.0.0 6.84142E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99399E-06 0 0
V/M 10088 Ig-86 11 rs771073631 0.6646 -0.274 1.0 None 0.522 0.287 0.621334715683 gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 4.64E-05 0 0
V/M 10088 Ig-86 11 rs771073631 0.6646 -0.274 1.0 None 0.522 0.287 0.621334715683 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 9.44E-05 0 0 0 0
V/M 10088 Ig-86 11 rs771073631 0.6646 -0.274 1.0 None 0.522 0.287 0.621334715683 gnomAD-4.0.0 1.11538E-05 None None None None N None 0 0 None 0 0 None 4.68794E-05 0 8.47551E-06 3.29395E-05 3.20184E-05
I/S 13693 Ig-87 10 None 0.4746 None 0.001 N 0.367 0.258 0.619501705969 gnomAD-4.0.0 1.59222E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85989E-06 0 0
I/V 13693 Ig-87 10 None 0.0671 None None N 0.11 0.116 0.170165803431 gnomAD-4.0.0 6.36894E-06 None None None None I None 0 0 None 0 0 None 0 0 1.14395E-05 0 0
T/I 13791 Ig-88 12 rs2154230629 0.4616 None 0.994 N 0.449 0.366 0.250039746154 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
T/I 13791 Ig-88 12 rs2154230629 0.4616 None 0.994 N 0.449 0.366 0.250039746154 gnomAD-4.0.0 6.57376E-06 None None None None N None 0 6.54965E-05 None 0 0 None 0 0 0 0 0
H/Q 13884 Ig-89 9 rs1361052408 0.8367 0.195 0.988 N 0.517 0.204 0.177238962908 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
H/Q 13884 Ig-89 9 rs1361052408 0.8367 0.195 0.988 N 0.517 0.204 0.177238962908 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
H/Q 13884 Ig-89 9 rs1361052408 0.8367 0.195 0.988 N 0.517 0.204 0.177238962908 gnomAD-4.0.0 2.49721E-06 None None None None N None 0 0 None 0 0 None 0 0 3.40783E-06 0 0
H/R 13884 Ig-89 9 rs1432673437 0.7552 -0.02 0.92 N 0.509 0.268 0.17948927462 gnomAD-2.1.1 4.34E-06 None None None None N None 0 0 None 0 0 None 3.54E-05 None 0 0 0
H/R 13884 Ig-89 9 rs1432673437 0.7552 -0.02 0.92 N 0.509 0.268 0.17948927462 gnomAD-4.0.0 6.89733E-06 None None None None N None 0 0 None 0 0 None 0 0 7.23444E-06 1.18649E-05 1.66722E-05
H/Y 13884 Ig-89 9 None 0.4676 None 0.993 N 0.515 0.416 0.198526703765 gnomAD-4.0.0 1.62177E-06 None None None None N None 0 0 None 0 0 None 1.91476E-05 0 0 0 0
T/I 13975 Ig-90 11 rs1417052657 0.3504 0.088 0.966 N 0.524 0.226 0.244539031024 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
T/I 13975 Ig-90 11 rs1417052657 0.3504 0.088 0.966 N 0.524 0.226 0.244539031024 gnomAD-4.0.0 1.31572E-05 None None None None N None 4.82952E-05 0 None 0 0 None 0 0 0 0 0
T/N 13975 Ig-90 11 rs1417052657 0.3081 -0.517 0.799 N 0.457 0.15 0.197625483188 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
T/N 13975 Ig-90 11 rs1417052657 0.3081 -0.517 0.799 N 0.457 0.15 0.197625483188 gnomAD-4.0.0 1.36884E-06 None None None None N None 0 2.23674E-05 None 0 0 None 0 0 0 1.15964E-05 0
T/S 13975 Ig-90 11 None 0.2557 None 0.622 N 0.503 0.114 0.126345400529 gnomAD-4.0.0 1.36884E-06 None None None None N None 5.98122E-05 0 None 0 0 None 0 0 0 0 0
T/A 14064 Ig-91 11 rs769719800 0.1558 -0.553 0.911 N 0.443 0.199 0.32306181527 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
T/A 14064 Ig-91 11 rs769719800 0.1558 -0.553 0.911 N 0.443 0.199 0.32306181527 gnomAD-3.1.2 1.32E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
T/A 14064 Ig-91 11 rs769719800 0.1558 -0.553 0.911 N 0.443 0.199 0.32306181527 gnomAD-4.0.0 7.43842E-06 None None None None N None 2.67201E-05 0 None 0 0 None 0 0 7.63008E-06 0 1.60179E-05
T/A 14152 Ig-92 11 rs1472786496 0.1278 -0.093 0.999 D 0.48 0.453 0.438170831126 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
T/A 14152 Ig-92 11 rs1472786496 0.1278 -0.093 0.999 D 0.48 0.453 0.438170831126 gnomAD-4.0.0 1.5927E-06 None None None None N None 5.66701E-05 0 None 0 0 None 0 0 0 0 0
T/A 14596 Ig-97 11 rs770795900 0.1044 -0.142 0.058 N 0.217 0.23 0.19670166235 gnomAD-2.1.1 4.08E-06 None None None None N None 0 0 None 0 0 None 3.3E-05 None 0 0 0
T/A 14596 Ig-97 11 rs770795900 0.1044 -0.142 0.058 N 0.217 0.23 0.19670166235 gnomAD-4.0.0 4.79126E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.87489E-05 3.03251E-05
T/I 14596 Ig-97 11 None 0.1943 None 0.942 D 0.433 0.417 0.573751148353 gnomAD-4.0.0 2.40068E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62504E-06 0 0
T/S 14596 Ig-97 11 None 0.1566 None 0.014 N 0.27 0.168 0.221734844693 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31252E-06 0 0
E/K 14685 Ig-98 11 rs1473069344 0.776 0.47 0.997 N 0.74 0.385 0.227260227426 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
E/K 14685 Ig-98 11 rs1473069344 0.776 0.47 0.997 N 0.74 0.385 0.227260227426 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 3.87747E-04 None 0 0 0 0 0
E/K 14685 Ig-98 11 rs1473069344 0.776 0.47 0.997 N 0.74 0.385 0.227260227426 gnomAD-4.0.0 1.79467E-05 None None None None N None 0 0 None 0 2.6777E-04 None 0 0 7.18353E-06 0 0
T/A 14774 Ig-99 10 rs748139496 0.1308 -0.01 0.999 N 0.516 0.327 0.355034743287 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
T/A 14774 Ig-99 10 rs748139496 0.1308 -0.01 0.999 N 0.516 0.327 0.355034743287 gnomAD-4.0.0 3.18608E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86664E-05 0
T/I 14774 Ig-99 10 rs930837832 0.2535 0.074 1.0 D 0.638 0.479 0.642532236133 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
T/I 14774 Ig-99 10 rs930837832 0.2535 0.074 1.0 D 0.638 0.479 0.642532236133 gnomAD-4.0.0 1.5931E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86174E-06 0 0
T/K 14863 Ig-100 11 None 0.3381 None 0.967 N 0.583 0.443 0.415564226483 gnomAD-4.0.0 2.73913E-06 None None None None N None 0 0 None 0 0 None 0 0 2.7001E-06 1.1599E-05 0
T/M 14863 Ig-100 11 rs759406486 0.1172 0.085 1.0 D 0.602 0.567 None gnomAD-2.1.1 5.02E-05 None None None None N None 4.15E-05 0 None 0 0 None 2.6154E-04 None 0 3.93E-05 0
T/M 14863 Ig-100 11 rs759406486 0.1172 0.085 1.0 D 0.602 0.567 None gnomAD-3.1.2 6.58E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 1.32509E-04 0 0
T/M 14863 Ig-100 11 rs759406486 0.1172 0.085 1.0 D 0.602 0.567 None gnomAD-4.0.0 4.9002E-05 None None None None N None 4.01198E-05 0 None 0 2.23824E-05 None 0 0 4.1561E-05 2.63626E-04 3.20646E-05
T/R 14863 Ig-100 11 rs759406486 0.2859 0.133 0.99 N 0.635 0.471 0.500363902356 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
T/R 14863 Ig-100 11 rs759406486 0.2859 0.133 0.99 N 0.635 0.471 0.500363902356 gnomAD-4.0.0 9.58697E-06 None None None None N None 0 0 None 0 0 None 0 0 1.17004E-05 0 1.65876E-05
E/G 15041 Ig-102 11 None 0.2714 None 0.946 D 0.645 0.53 0.476676017676 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
E/K 15130 Ig-103 11 rs772087689 0.6623 0.815 0.999 N 0.657 0.4 0.472582640538 gnomAD-2.1.1 2.03E-05 None None None None I None 0 0 None 0 0 None 0 None 2.33231E-04 0 0
E/K 15130 Ig-103 11 rs772087689 0.6623 0.815 0.999 N 0.657 0.4 0.472582640538 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 9.44E-05 0 1.47E-05 0 0
E/K 15130 Ig-103 11 rs772087689 0.6623 0.815 0.999 N 0.657 0.4 0.472582640538 gnomAD-4.0.0 1.66972E-05 None None None None I None 0 0 None 0 0 None 1.41492E-04 0 9.59049E-06 0 0
E/V 15130 Ig-103 11 rs1473655528 0.5318 0.408 1.0 N 0.653 0.499 0.500742145641 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 6.59631E-04 None 0 None 0 0 0
E/V 15130 Ig-103 11 rs1473655528 0.5318 0.408 1.0 N 0.653 0.499 0.500742145641 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 1.9516E-04 None 0 0 0 0 0
E/V 15130 Ig-103 11 rs1473655528 0.5318 0.408 1.0 N 0.653 0.499 0.500742145641 gnomAD-4.0.0 6.58146E-06 None None None None I None 0 0 None 0 1.9516E-04 None 0 0 0 0 0
R/Q 15218 Ig-104 11 rs548035065 0.0986 0.087 0.002 N 0.217 0.092 0.165133752707 gnomAD-2.1.1 8.09E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 8.96E-06 0
R/Q 15218 Ig-104 11 rs548035065 0.0986 0.087 0.002 N 0.217 0.092 0.165133752707 gnomAD-3.1.2 1.98E-05 None None None None N None 4.83E-05 6.57E-05 0 0 0 None 0 0 0 0 0
R/Q 15218 Ig-104 11 rs548035065 0.0986 0.087 0.002 N 0.217 0.092 0.165133752707 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
R/Q 15218 Ig-104 11 rs548035065 0.0986 0.087 0.002 N 0.217 0.092 0.165133752707 gnomAD-4.0.0 7.44314E-06 None None None None N None 2.67123E-05 1.67185E-05 None 0 0 None 0 1.65508E-04 3.39238E-06 2.19833E-05 3.20677E-05
R/W 15218 Ig-104 11 rs371621174 0.1831 -0.489 0.964 N 0.331 0.322 None gnomAD-2.1.1 4.05E-05 None None None None N None 6.48E-05 2.92E-05 None 0 0 None 3.28E-05 None 9.3E-05 3.58E-05 1.67336E-04
R/W 15218 Ig-104 11 rs371621174 0.1831 -0.489 0.964 N 0.331 0.322 None gnomAD-3.1.2 4.61E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 7.37E-05 0 4.78927E-04
R/W 15218 Ig-104 11 rs371621174 0.1831 -0.489 0.964 N 0.331 0.322 None gnomAD-4.0.0 4.5905E-05 None None None None N None 4.01456E-05 3.3456E-05 None 3.38364E-05 0 None 1.56377E-05 0 5.08867E-05 1.09931E-05 9.62371E-05
E/K 15312 Ig-105 11 None 0.3908 None 0.978 N 0.508 0.447 0.416581338634 gnomAD-4.0.0 1.59785E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86878E-06 0 0
E/Q 15312 Ig-105 11 rs748340315 0.29 0.024 0.989 N 0.484 0.294 0.409124616982 gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 3.3E-05 None 0 0 0
E/Q 15312 Ig-105 11 rs748340315 0.29 0.024 0.989 N 0.484 0.294 0.409124616982 gnomAD-4.0.0 3.19569E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.87737E-05 0
T/I 15401 Ig-106 11 None 0.3997 None 1.0 D 0.67 0.482 0.512707719942 gnomAD-4.0.0 1.6578E-06 None None None None N None 0 0 None 0 0 None 1.92057E-05 0 0 0 0
T/R 15401 Ig-106 11 rs2058077890 0.3897 None 1.0 N 0.657 0.421 0.553063759574 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06782E-04 0
T/R 15401 Ig-106 11 rs2058077890 0.3897 None 1.0 N 0.657 0.421 0.553063759574 gnomAD-4.0.0 2.64855E-06 None None None None N None 0 0 None 0 2.4481E-05 None 0 0 0 1.43098E-05 0
L/I 15490 Ig-107 11 None 0.0926 None 0.669 N 0.336 0.158 0.366466682447 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
V/A 15578 Ig-108 11 None 0.2441 None 0.999 N 0.496 0.431 0.656528602549 gnomAD-4.0.0 1.59845E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86668E-06 0 0
E/K 15973 Ig-109 6 rs375099780 0.6378 0.713 0.998 N 0.557 0.338 None gnomAD-2.1.1 2.15E-05 None None None None I None 2.48303E-04 0 None 0 0 None 0 None 0 0 0
E/K 15973 Ig-109 6 rs375099780 0.6378 0.713 0.998 N 0.557 0.338 None gnomAD-3.1.2 2.63E-05 None None None None I None 9.67E-05 0 0 0 0 None 0 0 0 0 0
E/K 15973 Ig-109 6 rs375099780 0.6378 0.713 0.998 N 0.557 0.338 None gnomAD-4.0.0 5.58146E-06 None None None None I None 1.20376E-04 0 None 0 0 None 0 0 0 0 0
I/M 16965 Ig-111 11 None 0.1303 None 0.317 N 0.369 0.045 0.510172456258 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Q/K 17683 Ig-113 7 None 0.1257 None 0.811 N 0.323 0.248 0.211220785272 gnomAD-4.0.0 3.18579E-06 None None None None I None 0 0 None 0 2.77932E-05 None 0 0 0 0 3.02865E-05
K/N 17977 Ig-114 10 None 0.6592 None 0.912 N 0.351 0.255 0.239305524855 gnomAD-4.0.0 1.60552E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87974E-06 0 0
K/Q 17977 Ig-114 10 None 0.209 None 0.947 N 0.385 0.254 0.263140351381 gnomAD-4.0.0 6.86935E-07 None None None None N None 0 0 None 0 0 None 0 0 9.01656E-07 0 0
V/L 18389 Ig-115 8 None 0.1477 None None N 0.131 0.168 0.115124310173 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
E/K 18695 Ig-116 8 rs752314096 0.683 0.13 0.998 N 0.566 0.473 0.499921029546 gnomAD-2.1.1 1.28E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.77E-05 0
E/K 18695 Ig-116 8 rs752314096 0.683 0.13 0.998 N 0.566 0.473 0.499921029546 gnomAD-3.1.2 1.97E-05 None None None None N None 2.41E-05 6.56E-05 0 0 0 None 0 0 1.47E-05 0 0
E/K 18695 Ig-116 8 rs752314096 0.683 0.13 0.998 N 0.566 0.473 0.499921029546 gnomAD-4.0.0 1.37649E-05 None None None None N None 1.35406E-05 3.50619E-05 None 0 0 None 0 0 1.61882E-05 0 0
V/A 19103 Ig-117 9 None 0.3232 None 0.998 N 0.496 0.402 0.722099309044 gnomAD-4.0.0 4.80129E-06 None None None None I None 0 0 None 0 0 None 0 0 5.25001E-06 0 0
V/I 19103 Ig-117 9 None 0.0848 None 0.767 D 0.307 0.262 0.547212138244 gnomAD-4.0.0 4.10669E-06 None None None None I None 0 0 None 0 0 None 0 0 5.3978E-06 0 0
T/M 19397 Ig-118 7 rs373527448 0.0931 -0.062 0.005 N 0.191 0.066 None gnomAD-2.1.1 8.23E-05 None None None None I None 4.13E-05 4.82352E-04 None 0 0 None 0 None 0 1.57E-05 4.22297E-04
T/M 19397 Ig-118 7 rs373527448 0.0931 -0.062 0.005 N 0.191 0.066 None gnomAD-3.1.2 1.381E-04 None None None None I None 1.20639E-04 7.86473E-04 0 0 0 None 0 0 4.41E-05 0 4.79846E-04
T/M 19397 Ig-118 7 rs373527448 0.0931 -0.062 0.005 N 0.191 0.066 None 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
T/M 19397 Ig-118 7 rs373527448 0.0931 -0.062 0.005 N 0.191 0.066 None gnomAD-4.0.0 3.96696E-05 None None None None I None 7.99701E-05 6.33883E-04 None 0 2.23814E-05 None 0 0 1.2716E-05 1.0981E-05 4.80354E-05
T/P 19397 Ig-118 7 None 0.2885 None 0.266 N 0.387 0.328 0.52463718601 gnomAD-4.0.0 2.0417E-05 None None None None I None 0 0 None 0 0 None 0 0 2.1012E-05 6.07755E-05 0
H/Y 19797 Ig-119 8 rs2050464910 0.1198 None 0.001 N 0.125 0.094 0.18995819373 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
H/Y 19797 Ig-119 8 rs2050464910 0.1198 None 0.001 N 0.125 0.094 0.18995819373 gnomAD-4.0.0 6.57592E-06 None None None None I None 2.41324E-05 0 None 0 0 None 0 0 0 0 0
V/A 20089 Ig-120 10 rs886039085 0.3586 -0.497 0.91 N 0.469 0.217 0.557597400255 gnomAD-2.1.1 1.76E-05 None None None None I None 0 6.82E-05 None 0 0 None 0 None 0 9.39E-06 1.81951E-04
V/A 20089 Ig-120 10 rs886039085 0.3586 -0.497 0.91 N 0.469 0.217 0.557597400255 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.56E-05 0 0 0 None 0 0 0 0 0
V/A 20089 Ig-120 10 rs886039085 0.3586 -0.497 0.91 N 0.469 0.217 0.557597400255 gnomAD-4.0.0 2.32634E-05 None None None None I None 0 7.31957E-05 None 0 0 None 0 1.67448E-04 2.47478E-05 0 4.87916E-05
V/M 20089 Ig-120 10 rs2050176457 0.2373 None 0.994 D 0.488 0.275 None gnomAD-4.0.0 1.65421E-06 None None None None I None 0 0 None 0 0 None 0 0 2.92694E-06 0 0
I/T 21185 Ig-123 9 rs794729473 0.0585 None None N 0.093 0.126 0.132336055621 gnomAD-4.0.0 2.40065E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 6.07533E-05 0
I/V 21185 Ig-123 9 rs1329536424 0.0652 None None N 0.086 0.11 0.46614307118 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 21185 Ig-123 9 rs1329536424 0.0652 None None N 0.086 0.11 0.46614307118 gnomAD-4.0.0 6.57601E-06 None None None None I None 2.41266E-05 0 None 0 0 None 0 0 0 0 0
T/N 21874 Ig-125 9 rs758979983 0.2464 -0.068 0.999 N 0.584 0.264 0.484837542351 gnomAD-2.1.1 4.07E-06 None None None None I None 0 0 None 0 0 None 0 None 4.67E-05 0 0
T/N 21874 Ig-125 9 rs758979983 0.2464 -0.068 0.999 N 0.584 0.264 0.484837542351 gnomAD-4.0.0 1.59899E-06 None None None None I None 0 0 None 0 0 None 1.8858E-05 0 0 0 0
T/P 21874 Ig-125 9 None 0.2085 None 0.999 N 0.639 0.463 0.516437024119 gnomAD-4.0.0 6.85687E-07 None None None None I None 0 0 None 0 2.53601E-05 None 0 0 0 0 0
T/S 21874 Ig-125 9 rs780643085 0.2302 -0.164 0.989 N 0.459 0.186 0.249502417897 gnomAD-2.1.1 1.63E-05 None None None None I None 0 0 None 0 0 None 1.31518E-04 None 0 0 0
T/S 21874 Ig-125 9 rs780643085 0.2302 -0.164 0.989 N 0.459 0.186 0.249502417897 gnomAD-4.0.0 4.79981E-06 None None None None I None 0 0 None 0 0 None 0 0 0 8.15148E-05 0
I/M 22272 Ig-126 8 rs1460711951 0.1628 None 0.97 N 0.43 0.176 0.542808479177 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/M 22272 Ig-126 8 rs1460711951 0.1628 None 0.97 N 0.43 0.176 0.542808479177 gnomAD-4.0.0 2.03001E-06 None None None None I None 0 0 None 0 0 None 0 0 2.40997E-06 0 0
I/T 22272 Ig-126 8 rs773998250 0.2261 -0.664 0.822 N 0.358 0.304 0.638501922959 gnomAD-2.1.1 2.03E-05 None None None None I None 0 2.92E-05 None 0 0 None 0 None 0 3.59E-05 0
I/T 22272 Ig-126 8 rs773998250 0.2261 -0.664 0.822 N 0.358 0.304 0.638501922959 gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 0 0 None 0 0 4.41E-05 0 0
I/T 22272 Ig-126 8 rs773998250 0.2261 -0.664 0.822 N 0.358 0.304 0.638501922959 gnomAD-4.0.0 1.48854E-05 None None None None I None 0 1.67012E-05 None 0 0 None 0 0 1.69607E-05 0 4.80939E-05
L/F 22561 Ig-127 2 rs876658076 0.1521 None 0.966 N 0.353 0.164 0.281381271821 gnomAD-4.0.0 1.38023E-06 None None None None I None 0 0 None 0 0 None 0 0 1.80786E-06 0 0
V/F 23355 Ig-129 11 rs1249051519 0.3796 None 0.983 N 0.537 0.536 None gnomAD-4.0.0 4.10584E-06 None None None None I None 0 0 None 0 0 None 0 0 5.3975E-06 0 0
V/I 23355 Ig-129 11 rs1249051519 0.0827 -0.113 0.873 N 0.449 0.268 0.676505548274 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 9.95E-05 0 None 0 None 0 0 0
V/I 23355 Ig-129 11 rs1249051519 0.0827 -0.113 0.873 N 0.449 0.268 0.676505548274 gnomAD-4.0.0 6.84306E-07 None None None None I None 0 0 None 3.82731E-05 0 None 0 0 0 0 0
V/L 23355 Ig-129 11 None 0.306 None 0.773 N 0.431 0.326 0.68224456972 gnomAD-4.0.0 6.84306E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99583E-07 0 0
I/S 23644 Ig-130 8 None 0.5127 None 0.884 N 0.387 0.455 0.750485479121 gnomAD-4.0.0 1.59348E-06 None None None None N None 0 0 None 0 0 None 1.88445E-05 0 0 0 0
I/L 24040 Ig-131 12 None 0.0809 None 0.002 N 0.224 0.115 0.405012372841 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 24040 Ig-131 12 None 0.105 None None N 0.163 0.126 0.270889551736 gnomAD-4.0.0 1.36874E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79916E-06 0 0
T/I 24439 Ig-132 9 rs750110781 0.1207 0.297 0.006 N 0.255 0.118 None gnomAD-2.1.1 8.06E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 8.92E-06 0
T/I 24439 Ig-132 9 rs750110781 0.1207 0.297 0.006 N 0.255 0.118 None gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/I 24439 Ig-132 9 rs750110781 0.1207 0.297 0.006 N 0.255 0.118 None gnomAD-4.0.0 5.12694E-06 None None None None I None 5.07683E-05 0 None 0 0 None 0 0 2.3942E-06 0 0
T/A 24726 Ig-133 11 rs1559408209 0.1085 None 0.267 N 0.207 0.253 0.366659145958 gnomAD-2.1.1 4.03E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
T/A 24726 Ig-133 11 rs1559408209 0.1085 None 0.267 N 0.207 0.253 0.366659145958 gnomAD-4.0.0 4.1065E-06 None None None None N None 2.98989E-05 0 None 0 0 None 0 0 4.49798E-06 0 0
T/I 24726 Ig-133 11 rs975263285 0.3448 None 0.966 N 0.382 0.355 0.556105722742 gnomAD-4.0.0 9.58161E-06 None None None None N None 0 0 None 0 0 None 0 0 1.25942E-05 0 0
T/S 24726 Ig-133 11 None 0.0967 None 0.007 N 0.097 0.218 0.292423486923 gnomAD-4.0.0 6.84417E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99596E-07 0 0
V/M 25122 Ig-134 12 rs376821762 0.1317 -0.321 0.999 N 0.532 0.296 None gnomAD-2.1.1 5.64E-05 None None None None N None 0 8.69E-05 None 9.96E-05 0 None 3.27E-05 None 0 8.02E-05 0
V/M 25122 Ig-134 12 rs376821762 0.1317 -0.321 0.999 N 0.532 0.296 None gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
V/M 25122 Ig-134 12 rs376821762 0.1317 -0.321 0.999 N 0.532 0.296 None gnomAD-4.0.0 8.61509E-05 None None None None N None 0 6.66889E-05 None 3.37883E-05 0 None 0 0 1.11899E-04 1.09796E-05 1.60143E-05
S/R 25808 Ig-136 11 rs1415635107 0.8802 None 0.056 D 0.291 0.328 0.295974979623 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/R 25808 Ig-136 11 rs1415635107 0.8802 None 0.056 D 0.291 0.328 0.295974979623 gnomAD-4.0.0 6.57419E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47042E-05 0 0
S/T 25808 Ig-136 11 None 0.0973 None 0.892 N 0.389 0.273 0.282575091529 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/M 26204 Ig-137 12 None 0.1794 None 0.994 N 0.516 0.372 0.613122972663 gnomAD-4.0.0 2.74056E-06 None None None None I None 0 0 None 0 0 None 0 0 3.60023E-06 0 0
V/A 26603 Ig-138 10 rs376882944 0.2099 -0.474 0.006 D 0.206 0.211 None gnomAD-2.1.1 3.19E-05 None None None None I None 1.14811E-04 0 None 0 0 None 0 None 0 0 0
V/A 26603 Ig-138 10 rs376882944 0.2099 -0.474 0.006 D 0.206 0.211 None gnomAD-3.1.2 1.32E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/A 26603 Ig-138 10 rs376882944 0.2099 -0.474 0.006 D 0.206 0.211 None gnomAD-4.0.0 3.04521E-06 None None None None I None 5.24421E-05 0 None 0 0 None 0 0 0 0 0
V/F 26603 Ig-138 10 rs914913478 0.2116 -0.539 0.627 N 0.447 0.227 0.60543932511 gnomAD-2.1.1 7.14E-06 None None None None I None 0 0 None 0 0 None 0 None 0 7.81E-06 1.40449E-04
V/F 26603 Ig-138 10 rs914913478 0.2116 -0.539 0.627 N 0.447 0.227 0.60543932511 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
V/F 26603 Ig-138 10 rs914913478 0.2116 -0.539 0.627 N 0.447 0.227 0.60543932511 gnomAD-4.0.0 2.47912E-06 None None None None I None 0 0 None 0 0 None 0 0 3.39067E-06 0 0
S/N 26890 Ig-139 11 rs766880487 0.1654 0.155 None N 0.164 0.125 0.162503812791 gnomAD-2.1.1 1.07E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.35E-05 0
S/N 26890 Ig-139 11 rs766880487 0.1654 0.155 None N 0.164 0.125 0.162503812791 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
S/N 26890 Ig-139 11 rs766880487 0.1654 0.155 None N 0.164 0.125 0.162503812791 gnomAD-4.0.0 7.43908E-06 None None None None I None 0 0 None 0 0 None 0 0 1.01732E-05 0 0
V/A 27286 Ig-140 9 rs1704824668 0.2142 None 0.055 N 0.59 0.265 0.529813890454 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/A 27286 Ig-140 9 rs1704824668 0.2142 None 0.055 N 0.59 0.265 0.529813890454 gnomAD-4.0.0 3.04491E-06 None None None None I None 0 0 None 0 0 None 0 0 3.61484E-06 0 0
V/I 27286 Ig-140 9 rs372784067 0.075 0.018 0.002 N 0.167 0.081 None gnomAD-2.1.1 2.82E-05 None None None None I None 1.93849E-04 2.9E-05 None 0 0 None 9.8E-05 None 0 0 0
V/I 27286 Ig-140 9 rs372784067 0.075 0.018 0.002 N 0.167 0.081 None gnomAD-3.1.2 1.05168E-04 None None None None I None 3.86007E-04 0 0 0 0 None 0 0 0 0 0
V/I 27286 Ig-140 9 rs372784067 0.075 0.018 0.002 N 0.167 0.081 None gnomAD-4.0.0 2.60347E-05 None None None None I None 3.73752E-04 3.33389E-05 None 0 0 None 0 0 4.23807E-06 6.58747E-05 1.60113E-05
V/I 27686 Ig-141 11 rs56309296 0.0716 0.062 None N 0.161 0.155 None gnomAD-2.1.1 5.99809E-03 None None None None I None 6.42107E-02 2.45971E-03 None 0 0 None 2.28758E-04 None 0 1.79522E-04 1.54278E-03
V/I 27686 Ig-141 11 rs56309296 0.0716 0.062 None N 0.161 0.155 None gnomAD-3.1.2 1.80159E-02 None None None None I None 6.32306E-02 5.05051E-03 0 0 0 None 0 3.16456E-03 2.49919E-04 6.21375E-04 1.14613E-02
V/I 27686 Ig-141 11 rs56309296 0.0716 0.062 None N 0.161 0.155 None 1000 genomes 1.61741E-02 None None None None I None 5.67E-02 8.6E-03 None None 0 0 None None None 0 None
V/I 27686 Ig-141 11 rs56309296 0.0716 0.062 None N 0.161 0.155 None gnomAD-4.0.0 3.41703E-03 None None None None I None 6.51455E-02 3.41735E-03 None 0 0 None 0 1.81578E-03 8.56137E-05 2.30567E-04 4.65779E-03
N/K 27973 Ig-142 11 None 0.5332 None None N 0.163 0.148 0.0297737177859 gnomAD-4.0.0 6.8475E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9979E-07 0 0
N/S 27973 Ig-142 11 None 0.0634 None None N 0.111 0.072 0.0954503805726 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 28368 Ig-143 11 None 0.2053 None 0.055 N 0.529 0.271 0.582764979894 gnomAD-4.0.0 1.59107E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85799E-06 0 0
V/F 28368 Ig-143 11 rs879238395 0.1967 -0.919 0.497 D 0.647 0.456 None gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
V/F 28368 Ig-143 11 rs879238395 0.1967 -0.919 0.497 D 0.647 0.456 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/F 28368 Ig-143 11 rs879238395 0.1967 -0.919 0.497 D 0.647 0.456 None gnomAD-4.0.0 4.33777E-06 None None None None I None 0 0 None 0 0 None 0 0 5.93319E-06 0 0
V/I 28368 Ig-143 11 None 0.085 None 0.001 N 0.208 0.117 0.568106843281 gnomAD-4.0.0 6.84179E-07 None None None None I None 0 0 None 0 0 None 0 1.7337E-04 0 0 0
I/F 28765 Ig-144 11 rs1216320411 0.2463 -0.643 0.627 N 0.346 0.29 0.576245406411 gnomAD-2.1.1 4.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
I/F 28765 Ig-144 11 rs1216320411 0.2463 -0.643 0.627 N 0.346 0.29 0.576245406411 gnomAD-4.0.0 1.59823E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.0259E-05
I/T 28765 Ig-144 11 rs1553561335 0.1414 None 0.006 N 0.247 0.177 0.546736107678 gnomAD-4.0.0 6.16952E-06 None None None None I None 0 0 None 0 0 None 0 0 8.09597E-06 0 0
T/A 30142 Ig-148 11 None 0.0682 None None N 0.111 0.105 0.247322355667 gnomAD-4.0.0 2.05658E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.32083E-05 1.66052E-05
T/I 30142 Ig-148 11 rs754759596 0.1596 None 0.055 N 0.35 0.124 0.401327265625 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/I 30142 Ig-148 11 rs754759596 0.1596 None 0.055 N 0.35 0.124 0.401327265625 gnomAD-4.0.0 6.57125E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46972E-05 0 0
T/N 30142 Ig-148 11 None 0.1218 None 0.029 N 0.197 0.08 0.377274123778 gnomAD-4.0.0 6.85568E-07 None None None None I None 0 0 None 0 0 None 0 0 9.01349E-07 0 0
T/S 30142 Ig-148 11 rs754759596 0.1024 -0.098 None N 0.119 0.11 0.230578612272 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.28E-05 None 0 0 0
T/S 30142 Ig-148 11 rs754759596 0.1024 -0.098 None N 0.119 0.11 0.230578612272 gnomAD-4.0.0 6.85568E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.16047E-05 0
I/N 30537 Ig-149 6 None 0.1044 None None N 0.209 0.274 0.232513804876 gnomAD-4.0.0 6.84354E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99604E-07 0 0
I/S 30537 Ig-149 6 rs758126299 0.1247 -0.924 0.012 N 0.26 0.183 0.232513804876 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
I/S 30537 Ig-149 6 rs758126299 0.1247 -0.924 0.012 N 0.26 0.183 0.232513804876 gnomAD-4.0.0 2.73742E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59842E-06 0 0
V/I 30936 Ig-150 10 rs200476500 0.0588 -0.126 None N 0.143 0.115 None gnomAD-2.1.1 7.25E-05 None None None None I None 0 0 None 0 0 None 0 None 0 1.59889E-04 0
V/I 30936 Ig-150 10 rs200476500 0.0588 -0.126 None N 0.143 0.115 None gnomAD-3.1.2 7.23E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 1.3231E-04 0 0
V/I 30936 Ig-150 10 rs200476500 0.0588 -0.126 None N 0.143 0.115 None gnomAD-4.0.0 1.80439E-04 None None None None I None 4.00502E-05 0 None 0 0 None 0 0 2.41565E-04 0 4.80384E-05
T/I 31626 Ig-152 6 rs542160074 0.1796 0.334 0.991 N 0.558 0.405 0.648841342166 gnomAD-2.1.1 1.62E-05 None None None None I None 0 0 None 0 0 None 1.30762E-04 None 0 0 0
T/I 31626 Ig-152 6 rs542160074 0.1796 0.334 0.991 N 0.558 0.405 0.648841342166 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
T/I 31626 Ig-152 6 rs542160074 0.1796 0.334 0.991 N 0.558 0.405 0.648841342166 gnomAD-4.0.0 7.68819E-06 None None None None I None 0 0 None 0 0 None 0 0 0 8.04203E-05 0
T/N 31626 Ig-152 6 rs542160074 0.1985 -0.017 0.982 N 0.536 0.28 0.564208378351 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.95E-06 0
T/N 31626 Ig-152 6 rs542160074 0.1985 -0.017 0.982 N 0.536 0.28 0.564208378351 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/N 31626 Ig-152 6 rs542160074 0.1985 -0.017 0.982 N 0.536 0.28 0.564208378351 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 1E-03 None None None 0 None
T/N 31626 Ig-152 6 rs542160074 0.1985 -0.017 0.982 N 0.536 0.28 0.564208378351 gnomAD-4.0.0 6.56737E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47024E-05 0 0
T/I 32025 Ig-153 9 rs1259754105 0.1119 None None N 0.194 0.1 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/I 32025 Ig-153 9 rs1259754105 0.1119 None None N 0.194 0.1 None gnomAD-4.0.0 3.84548E-06 None None None None N None 3.38387E-05 0 None 0 0 None 0 0 0 1.34073E-05 0
H/D 32317 Ig-154 11 rs779019939 0.6962 -0.415 0.852 N 0.343 0.207 0.256283259241 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.96E-06 0
H/D 32317 Ig-154 11 rs779019939 0.6962 -0.415 0.852 N 0.343 0.207 0.256283259241 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
H/D 32317 Ig-154 11 rs779019939 0.6962 -0.415 0.852 N 0.343 0.207 0.256283259241 gnomAD-4.0.0 3.84689E-06 None None None None I None 0 0 None 0 0 None 0 0 7.18976E-06 0 0
H/Y 32317 Ig-154 11 None 0.1524 None 0.134 N 0.244 0.16 0.239901079897 gnomAD-4.0.0 1.5931E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43345E-05 0
F/L 32715 Ig-155 8 rs1693570743 0.5103 None None N 0.11 0.081 0.374970422459 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
F/L 32715 Ig-155 8 rs1693570743 0.5103 None None N 0.11 0.081 0.374970422459 gnomAD-4.0.0 6.5703E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47007E-05 0 0
F/S 32715 Ig-155 8 None 0.1615 None None N 0.209 0.244 0.420447328233 gnomAD-4.0.0 1.59133E-06 None None None None N None 0 2.28655E-05 None 0 0 None 0 0 0 0 0
F/V 32715 Ig-155 8 None 0.0897 None None N 0.131 0.1 0.466740653422 gnomAD-4.0.0 9.57915E-06 None None None None N None 0 0 None 0 0 None 0 0 1.25929E-05 0 0
R/S 34952 Ig-163 11 rs765379292 0.8781 0.005 1.0 N 0.733 0.318 0.383590876969 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 5.56E-05 None 0 None 0 0 0
R/S 34952 Ig-163 11 rs765379292 0.8781 0.005 1.0 N 0.733 0.318 0.383590876969 gnomAD-4.0.0 3.18178E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85755E-06 0 3.02334E-05
R/T 34952 Ig-163 11 None 0.7034 None 1.0 N 0.729 0.492 0.621830897814 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 3.66327E-05
T/I 35139 Ig-164 11 rs200782068 0.1771 0.061 1.0 N 0.694 0.403 None gnomAD-2.1.1 4.28E-05 None None None None N None 0 2.83E-05 None 0 0 None 3.27E-05 None 4E-05 6.24E-05 1.40174E-04
T/I 35139 Ig-164 11 rs200782068 0.1771 0.061 1.0 N 0.694 0.403 None gnomAD-3.1.2 7.89E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 1.47003E-04 0 0
T/I 35139 Ig-164 11 rs200782068 0.1771 0.061 1.0 N 0.694 0.403 None gnomAD-4.0.0 4.58525E-05 None None None None N None 2.66987E-05 1.6665E-05 None 0 0 None 1.56206E-05 1.15056E-03 4.15294E-05 1.31744E-04 3.20174E-05
T/N 35139 Ig-164 11 None 0.164 None 1.0 N 0.685 0.317 0.503683571763 gnomAD-4.0.0 6.84135E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99392E-07 0 0
A/V 35296 Ig-165 11 None 0.1675 None 0.626 N 0.422 0.218 0.12205267543 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/A 35430 Ig-166 11 rs1225799039 0.0905 -0.495 0.271 D 0.403 0.076 0.181679512989 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
T/A 35430 Ig-166 11 rs1225799039 0.0905 -0.495 0.271 D 0.403 0.076 0.181679512989 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/A 35430 Ig-166 11 rs1225799039 0.0905 -0.495 0.271 D 0.403 0.076 0.181679512989 gnomAD-4.0.0 6.57099E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46985E-05 0 0
T/I 35430 Ig-166 11 None 0.1762 None 0.474 D 0.417 0.176 0.39709148275 gnomAD-4.0.0 1.59099E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85762E-06 0 0
T/S 35430 Ig-166 11 None 0.1253 None 0.01 N 0.099 0.056 0.184867976434 gnomAD-4.0.0 1.59099E-06 None None None None N None 0 0 None 0 2.77285E-05 None 0 0 0 0 0
N/H 35712 Ig-168 11 rs727504949 0.193 -0.97 1.0 N 0.667 0.353 0.310147130316 gnomAD-2.1.1 8.65E-05 None None None None N None 0 2.86E-05 None 0 1.19443E-03 None 0 None 0 0 0
N/H 35712 Ig-168 11 rs727504949 0.193 -0.97 1.0 N 0.667 0.353 0.310147130316 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 5.76923E-04 None 0 0 0 0 0
N/H 35712 Ig-168 11 rs727504949 0.193 -0.97 1.0 N 0.667 0.353 0.310147130316 gnomAD-4.0.0 1.61224E-05 None None None None N None 0 1.67179E-05 None 0 5.34974E-04 None 0 0 0 0 1.60215E-05
N/S 35712 Ig-168 11 None 0.1571 None 0.999 N 0.526 0.335 0.233150807113 gnomAD-4.0.0 6.84747E-07 None None None None N None 2.98811E-05 0 None 0 0 None 0 0 0 0 0
S/I 35907 Ig-169 11 rs773833357 0.2757 0.881 0.967 N 0.664 0.346 0.623070239186 gnomAD-2.1.1 1.22E-05 None None None -0.659(OBSL1) 0.03(OBSCN) N None 0 0 None 0 0 None 9.91E-05 None 0 0 0
S/I 35907 Ig-169 11 rs773833357 0.2757 0.881 0.967 N 0.664 0.346 0.623070239186 gnomAD-4.0.0 8.02409E-06 None None None -0.659(OBSL1) 0.03(OBSCN) N None 0 0 None 0 0 None 0 0 0 7.2015E-05 0
S/R 35907 Ig-169 11 rs977991321 0.7419 -0.37 0.967 N 0.649 0.306 0.426904299391 gnomAD-2.1.1 7.2E-06 None None None -1.399(OBSL1) -0.013(OBSCN) N None 0 0 None 0 0 None 0 None 0 1.58E-05 0
S/R 35907 Ig-169 11 rs977991321 0.7419 -0.37 0.967 N 0.649 0.306 0.426904299391 gnomAD-3.1.2 6.57E-06 None None None -1.399(OBSL1) -0.013(OBSCN) N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/R 35907 Ig-169 11 rs977991321 0.7419 -0.37 0.967 N 0.649 0.306 0.426904299391 gnomAD-4.0.0 9.32589E-06 None None None -1.399(OBSL1) -0.013(OBSCN) N None 0 0 None 0 0 None 0 0 1.19055E-05 0 1.60658E-05

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.