Structural position:
- Domain Type: Ig
- Aligned Position: 140
- Secondary Structure Element: e
- Secondary Structure Region: β-strand E
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| I/N | 67 |
Ig-1 |
62 | rs952685437 |
0.9778 | None | 1.0 | D | 0.911 | 0.879 | 0.924420087009 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | -0.616(TCAP) | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/N | 67 |
Ig-1 |
62 | rs952685437 |
0.9778 | None | 1.0 | D | 0.911 | 0.879 | 0.924420087009 | gnomAD-4.0.0 | 1.31546E-05 | None | None | None | -0.616(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94126E-05 | 0 | 0 |
| I/S | 163 |
Ig-2 |
60 | None | 0.9931 | None | 1.0 | D | 0.9 | 0.88 | 0.928496042275 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | -0.418(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 163 |
Ig-2 |
60 | rs2094004196 |
0.437 | None | 0.987 | D | 0.383 | 0.533 | 0.785477007334 | gnomAD-4.0.0 | 1.36812E-06 | None | None | None | -0.577(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31863E-05 | 0 |
| I/L | 1002 |
Ig-3 |
60 | rs879153744 |
0.7188 | -1.043 | 0.993 | D | 0.404 | 0.505 | None | gnomAD-2.1.1 | 1.59E-05 | None | None | None | None | N | None | 1.23047E-04 | 5.78E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/L | 1002 |
Ig-3 |
60 | rs879153744 |
0.7188 | -1.043 | 0.993 | D | 0.404 | 0.505 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 9.66E-05 | 1.30873E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 1002 |
Ig-3 |
60 | rs879153744 |
0.7188 | -1.043 | 0.993 | D | 0.404 | 0.505 | None | gnomAD-4.0.0 | 8.05466E-06 | None | None | None | None | N | None | 1.20154E-04 | 6.66622E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 1002 |
Ig-3 |
60 | None | 0.6286 | None | 0.993 | D | 0.373 | 0.506 | 0.764733137972 | gnomAD-4.0.0 | 1.36816E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.74406E-05 | 0 | 0 | 0 | 0 |
| I/L | 1143 |
Ig-4 |
62 | rs1466464278 |
0.5834 | -1.184 | 0.993 | D | 0.422 | 0.562 | 0.703432857381 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| I/L | 1143 |
Ig-4 |
62 | rs1466464278 |
0.5834 | -1.184 | 0.993 | D | 0.422 | 0.562 | 0.703432857381 | gnomAD-4.0.0 | 1.59077E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8568E-06 | 0 | 0 |
| I/M | 1517 |
Ig-6 |
61 | rs1438474327 |
0.3972 | -1.373 | 0.997 | D | 0.697 | 0.62 | 0.701978191309 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| I/M | 1517 |
Ig-6 |
61 | rs1438474327 |
0.3972 | -1.373 | 0.997 | D | 0.697 | 0.62 | 0.701978191309 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/M | 1517 |
Ig-6 |
61 | rs1438474327 |
0.3972 | -1.373 | 0.997 | D | 0.697 | 0.62 | 0.701978191309 | gnomAD-4.0.0 | 2.02973E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40978E-06 | 0 | 0 |
| I/T | 1899 |
Ig-9 |
59 | None | 0.9621 | None | 1.0 | D | 0.823 | 0.798 | 0.880129815424 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 1899 |
Ig-9 |
59 | rs878986033 |
0.182 | -1.644 | 0.993 | D | 0.405 | 0.421 | 0.779112364068 | gnomAD-2.1.1 | 1.59E-05 | None | None | None | None | N | None | 1.84593E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.63239E-04 |
| I/V | 1899 |
Ig-9 |
59 | rs878986033 |
0.182 | -1.644 | 0.993 | D | 0.405 | 0.421 | 0.779112364068 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 1899 |
Ig-9 |
59 | rs878986033 |
0.182 | -1.644 | 0.993 | D | 0.405 | 0.421 | 0.779112364068 | gnomAD-4.0.0 | 4.33691E-06 | None | None | None | None | N | None | 8.00726E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60036E-05 |
| I/M | 2138 |
Ig-10 |
61 | rs368391123 |
0.2252 | None | 1.0 | D | 0.76 | 0.612 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 2138 |
Ig-10 |
61 | rs368391123 |
0.2252 | None | 1.0 | D | 0.76 | 0.612 | None | gnomAD-4.0.0 | 3.04488E-06 | None | None | None | None | N | None | 5.24292E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 2138 |
Ig-10 |
61 | rs2092116298 |
0.1467 | None | 0.993 | D | 0.393 | 0.598 | 0.773490639186 | gnomAD-4.0.0 | 1.59068E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| I/T | 2233 |
Ig-11 |
60 | rs1364650008 |
0.8065 | -2.655 | 0.012 | D | 0.522 | 0.495 | 0.746771168191 | gnomAD-2.1.1 | 7.96E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 0 | 0 |
| I/T | 2233 |
Ig-11 |
60 | rs1364650008 |
0.8065 | -2.655 | 0.012 | D | 0.522 | 0.495 | 0.746771168191 | gnomAD-4.0.0 | 4.7726E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.29849E-05 | 0 |
| I/V | 2233 |
Ig-11 |
60 | rs1574638831 |
0.0676 | None | None | N | 0.257 | 0.273 | 0.308278614506 | gnomAD-4.0.0 | 2.05239E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99339E-07 | 0 | 3.31181E-05 |
| V/G | 2325 |
Ig-12 |
59 | None | 0.9608 | None | 0.997 | N | 0.877 | 0.727 | 0.920123548367 | gnomAD-4.0.0 | 1.59058E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85672E-06 | 0 | 0 |
| V/I | 2325 |
Ig-12 |
59 | None | 0.074 | None | 0.046 | N | 0.281 | 0.159 | 0.292423486923 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/L | 2414 |
Ig-13 |
59 | rs754815454 |
0.1974 | -1.128 | 0.001 | D | 0.298 | 0.327 | 0.422160833541 | gnomAD-2.1.1 | 7.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| I/L | 2414 |
Ig-13 |
59 | rs754815454 |
0.1974 | -1.128 | 0.001 | D | 0.298 | 0.327 | 0.422160833541 | gnomAD-4.0.0 | 1.36816E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79861E-06 | 0 | 0 |
| I/V | 2414 |
Ig-13 |
59 | None | 0.1081 | None | 0.002 | D | 0.283 | 0.262 | 0.555277862696 | gnomAD-4.0.0 | 4.10447E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39584E-06 | 0 | 0 |
| V/I | 2591 |
Ig-15 |
59 | None | 0.0881 | None | 0.003 | N | 0.235 | 0.073 | 0.229924730088 | gnomAD-4.0.0 | 1.36848E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79884E-06 | 0 | 0 |
| I/T | 2678 |
Ig-16 |
58 | rs1312609443 |
0.6124 | None | 0.961 | D | 0.785 | 0.779 | 0.840607677293 | gnomAD-4.0.0 | 1.59059E-06 | None | None | None | None | N | None | 5.65163E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 2678 |
Ig-16 |
58 | None | 0.1216 | None | 0.248 | D | 0.307 | 0.464 | 0.738248460819 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/F | 2766 |
Ig-17 |
60 | rs1414224093 |
0.6238 | -1.739 | 0.901 | D | 0.727 | 0.685 | 0.594255065555 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.45E-05 | None | 0 | None | 0 | 0 | 0 |
| I/F | 2766 |
Ig-17 |
60 | rs1414224093 |
0.6238 | -1.739 | 0.901 | D | 0.727 | 0.685 | 0.594255065555 | gnomAD-4.0.0 | 1.5905E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77346E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 2766 |
Ig-17 |
60 | rs755389555 |
0.9538 | -3.105 | 0.722 | D | 0.711 | 0.648 | 0.817529497908 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| I/T | 2766 |
Ig-17 |
60 | rs755389555 |
0.9538 | -3.105 | 0.722 | D | 0.711 | 0.648 | 0.817529497908 | gnomAD-4.0.0 | 1.59051E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85651E-06 | 0 | 0 |
| L/V | 2853 |
Ig-18 |
59 | rs1379690495 |
0.197 | -1.968 | 0.37 | N | 0.335 | 0.174 | 0.385578977469 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| L/V | 2853 |
Ig-18 |
59 | rs1379690495 |
0.197 | -1.968 | 0.37 | N | 0.335 | 0.174 | 0.385578977469 | gnomAD-4.0.0 | 1.59047E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| I/S | 2940 |
Ig-19 |
59 | None | 0.9925 | None | 1.0 | D | 0.837 | 0.898 | 0.914331358099 | gnomAD-4.0.0 | 1.59048E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| I/V | 2940 |
Ig-19 |
59 | rs939966359 |
0.1987 | None | 0.993 | D | 0.385 | 0.458 | 0.767465642132 | gnomAD-4.0.0 | 1.59048E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85652E-06 | 0 | 0 |
| I/M | 3116 |
Ig-21 |
59 | rs760230943 |
0.3079 | -1.193 | 1.0 | D | 0.761 | 0.638 | 0.674575032278 | gnomAD-2.1.1 | 5.58E-05 | None | None | None | None | N | None | 0 | 4.05069E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/M | 3116 |
Ig-21 |
59 | rs760230943 |
0.3079 | -1.193 | 1.0 | D | 0.761 | 0.638 | 0.674575032278 | gnomAD-4.0.0 | 2.06774E-05 | None | None | None | None | N | None | 0 | 2.97252E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/F | 3207 |
Ig-22 |
61 | None | 0.6401 | None | 1.0 | D | 0.815 | 0.802 | 0.728460520122 | gnomAD-4.0.0 | 1.59053E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88168E-05 | 0 | 0 | 0 | 0 |
| I/M | 3207 |
Ig-22 |
61 | rs750160721 |
0.5946 | -1.405 | 1.0 | D | 0.759 | 0.568 | 0.657556492978 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| I/M | 3207 |
Ig-22 |
61 | rs750160721 |
0.5946 | -1.405 | 1.0 | D | 0.759 | 0.568 | 0.657556492978 | gnomAD-4.0.0 | 3.18107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71311E-06 | 0 | 0 |
| I/T | 3207 |
Ig-22 |
61 | None | 0.9845 | None | 1.0 | D | 0.819 | 0.882 | 0.839964794171 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 3403 |
Ig-24 |
59 | None | 0.1156 | None | 0.001 | D | 0.248 | 0.268 | 0.485634191555 | gnomAD-4.0.0 | 3.18144E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41313E-04 | 0 | 0 | 3.02206E-05 |
| I/K | 3526 |
Ig-25 |
62 | rs727503677 |
0.8913 | -2.578 | None | None | None | 0.603 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/K | 3526 |
Ig-25 |
62 | rs727503677 |
0.8913 | -2.578 | None | None | None | 0.603 | None | gnomAD-4.0.0 | 6.84224E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15947E-05 | 0 |
| I/T | 3526 |
Ig-25 |
62 | rs727503677 |
0.6812 | None | None | None | None | 0.548 | None | gnomAD-4.0.0 | 2.7369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59801E-06 | 0 | 0 |
| I/V | 3526 |
Ig-25 |
62 | None | 0.1968 | None | None | None | None | 0.293 | None | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| I/L | 3719 |
Ig-26 |
60 | rs758911977 |
0.2286 | None | None | None | None | 0.266 | None | gnomAD-4.0.0 | 6.84188E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51978E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 3719 |
Ig-26 |
60 | rs758911977 |
0.125 | -1.369 | None | None | None | 0.258 | None | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 1.23987E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 3719 |
Ig-26 |
60 | rs758911977 |
0.125 | -1.369 | None | None | None | 0.258 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 3719 |
Ig-26 |
60 | rs758911977 |
0.125 | -1.369 | None | None | None | 0.258 | None | gnomAD-4.0.0 | 1.85897E-06 | None | None | None | None | N | None | 4.00342E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 3879 |
Ig-27 |
60 | rs765448965 |
0.1966 | -1.617 | 0.58 | D | 0.337 | 0.446 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| I/V | 3879 |
Ig-27 |
60 | rs765448965 |
0.1966 | -1.617 | 0.58 | D | 0.337 | 0.446 | None | gnomAD-4.0.0 | 3.42096E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51991E-05 | None | 0 | 0 | 3.5978E-06 | 0 | 0 |
| I/T | 4759 |
Ig-30 |
60 | None | 0.9923 | None | 0.896 | N | 0.765 | 0.78 | 0.799649619666 | gnomAD-4.0.0 | 1.59142E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85834E-06 | 0 | 0 |
| L/F | 4854 |
Ig-31 |
60 | rs1196213888 |
0.1717 | -1.755 | 0.942 | D | 0.731 | 0.489 | 0.651212884413 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/F | 4854 |
Ig-31 |
60 | rs1196213888 |
0.1717 | -1.755 | 0.942 | D | 0.731 | 0.489 | 0.651212884413 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 1.30959E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| L/F | 4854 |
Ig-31 |
60 | rs1196213888 |
0.1717 | -1.755 | 0.942 | D | 0.731 | 0.489 | 0.651212884413 |
Roncarati (2013)
| None |
DCM
|
het; co-inherited with LMNA mutant p.K219T | None | None | N | WES prioritisation in single DCM family; co-segregates with severe phenotype when inherited alongside LMNA variant K219T (n = 5, 5 severe phenotype (total 16)) | None | None | None | None | None | None | None | None | None | None | None |
| L/F | 4854 |
Ig-31 |
60 | rs1196213888 |
0.1717 | -1.755 | 0.942 | D | 0.731 | 0.489 | 0.651212884413 | gnomAD-4.0.0 | 7.68582E-06 | None | None | None | None | N | None | 1.69107E-05 | 5.08423E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 1.34005E-05 | 2.84349E-05 |
| I/T | 4947 |
Ig-32 |
60 | None | 0.934 | None | 1.0 | D | 0.823 | 0.833 | 0.860303665231 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| I/S | 5041 |
Ig-33 |
61 | rs752780850 |
0.8877 | -2.887 | 0.667 | D | 0.859 | 0.752 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| I/S | 5041 |
Ig-33 |
61 | rs752780850 |
0.8877 | -2.887 | 0.667 | D | 0.859 | 0.752 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/S | 5041 |
Ig-33 |
61 | rs752780850 |
0.8877 | -2.887 | 0.667 | D | 0.859 | 0.752 | None | gnomAD-4.0.0 | 8.96728E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.67514E-05 | 0 | 0 |
| I/V | 5041 |
Ig-33 |
61 | rs760814989 |
0.1126 | -1.51 | 0.001 | D | 0.268 | 0.252 | 0.565612946506 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.05086E-04 | None | 0 | None | 0 | 0 | 0 |
| I/V | 5041 |
Ig-33 |
61 | rs760814989 |
0.1126 | -1.51 | 0.001 | D | 0.268 | 0.252 | 0.565612946506 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92678E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 5041 |
Ig-33 |
61 | rs760814989 |
0.1126 | -1.51 | 0.001 | D | 0.268 | 0.252 | 0.565612946506 | gnomAD-4.0.0 | 4.95745E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.33708E-04 | None | 0 | 0 | 8.47614E-07 | 0 | 1.60113E-05 |
| I/T | 5134 |
Ig-34 |
60 | rs1362573029 |
0.9269 | -2.54 | 0.722 | D | 0.732 | 0.752 | 0.820698191142 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| I/T | 5134 |
Ig-34 |
60 | rs1362573029 |
0.9269 | -2.54 | 0.722 | D | 0.732 | 0.752 | 0.820698191142 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/T | 5134 |
Ig-34 |
60 | rs1362573029 |
0.9269 | -2.54 | 0.722 | D | 0.732 | 0.752 | 0.820698191142 | gnomAD-4.0.0 | 6.57082E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46959E-05 | 0 | 0 |
| I/F | 5227 |
Ig-35 |
60 | None | 0.1921 | None | 0.998 | D | 0.753 | 0.637 | 0.79036882002 | gnomAD-4.0.0 | 1.59116E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 5227 |
Ig-35 |
60 | rs2080946599 |
0.1582 | None | 0.333 | D | 0.261 | 0.304 | 0.64021514727 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 5227 |
Ig-35 |
60 | rs2080946599 |
0.1582 | None | 0.333 | D | 0.261 | 0.304 | 0.64021514727 | gnomAD-4.0.0 | 6.57117E-06 | None | None | None | None | N | None | 2.41231E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 5416 |
Ig-37 |
60 | None | 0.1244 | None | 0.994 | D | 0.677 | 0.645 | 0.756989136078 | gnomAD-4.0.0 | 2.05298E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69854E-06 | 0 | 0 |
| I/V | 5416 |
Ig-37 |
60 | rs1283439535 |
0.1223 | -1.753 | 0.4 | D | 0.287 | 0.497 | 0.717175623165 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/V | 5416 |
Ig-37 |
60 | rs1283439535 |
0.1223 | -1.753 | 0.4 | D | 0.287 | 0.497 | 0.717175623165 | gnomAD-4.0.0 | 2.73729E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99509E-07 | 2.31873E-05 | 1.65706E-05 |
| L/R | 5603 |
Ig-39 |
61 | rs956272919 |
0.5395 | -1.64 | 0.995 | N | 0.85 | 0.676 | 0.860091853005 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/R | 5603 |
Ig-39 |
61 | rs956272919 |
0.5395 | -1.64 | 0.995 | N | 0.85 | 0.676 | 0.860091853005 | gnomAD-4.0.0 | 6.81678E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32406E-06 | 0 | 0 |
| I/F | 5696 |
Ig-40 |
60 | None | 0.3326 | None | 0.497 | D | 0.689 | 0.526 | 0.433047596574 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/F | 5789 |
Ig-41 |
60 | None | 0.1541 | None | 0.175 | N | 0.665 | 0.264 | 0.530948259028 | gnomAD-4.0.0 | 3.18241E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71631E-06 | 0 | 0 |
| L/V | 5789 |
Ig-41 |
60 | rs778228033 |
0.0896 | -1.413 | None | N | 0.317 | 0.134 | 0.468586609112 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/V | 5789 |
Ig-41 |
60 | rs778228033 |
0.0896 | -1.413 | None | N | 0.317 | 0.134 | 0.468586609112 | gnomAD-4.0.0 | 1.59121E-06 | None | None | None | None | N | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 5882 |
Ig-42 |
60 | rs763665430 |
0.9278 | -3.363 | 0.939 | D | 0.753 | 0.793 | 0.831353130882 | gnomAD-2.1.1 | 6.42E-05 | None | None | None | None | N | None | 0 | 5.0954E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 5882 |
Ig-42 |
60 | rs763665430 |
0.9278 | -3.363 | 0.939 | D | 0.753 | 0.793 | 0.831353130882 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.31079E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 5882 |
Ig-42 |
60 | rs763665430 |
0.9278 | -3.363 | 0.939 | D | 0.753 | 0.793 | 0.831353130882 | gnomAD-4.0.0 | 2.69097E-05 | None | None | None | None | N | None | 0 | 3.55993E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/R | 6071 |
Ig-44 |
60 | None | 0.8589 | None | 0.928 | D | 0.884 | 0.735 | 0.863873001299 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/F | 6165 |
Ig-45 |
61 | None | 0.1669 | None | 0.901 | D | 0.723 | 0.681 | 0.631006925375 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85853E-06 | 0 | 0 |
| I/T | 6165 |
Ig-45 |
61 | None | 0.6472 | None | 0.722 | D | 0.705 | 0.683 | 0.833457243385 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 6165 |
Ig-45 |
61 | rs886055296 |
0.0965 | None | 0.001 | D | 0.28 | 0.257 | 0.630592674211 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85853E-06 | 0 | 0 |
| I/K | 6258 |
Ig-46 |
60 | rs746617599 |
0.968 | -2.194 | 0.939 | D | 0.82 | 0.832 | 0.926597058261 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| I/M | 6444 |
Ig-48 |
60 | None | 0.2138 | None | 0.968 | D | 0.697 | 0.763 | 0.672494282746 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/A | 6540 |
Ig-49 |
60 | rs1045155829 |
0.526 | None | None | N | 0.333 | 0.366 | 0.492475246742 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.50964E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 6540 |
Ig-49 |
60 | rs1157784163 |
0.0837 | -0.48 | None | N | 0.273 | 0.133 | 0.165133752707 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| V/I | 6540 |
Ig-49 |
60 | rs1157784163 |
0.0837 | -0.48 | None | N | 0.273 | 0.133 | 0.165133752707 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/I | 6540 |
Ig-49 |
60 | rs1157784163 |
0.0837 | -0.48 | None | N | 0.273 | 0.133 | 0.165133752707 | gnomAD-4.0.0 | 1.24006E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69581E-06 | 0 | 0 |
| M/L | 6727 |
Ig-51 |
61 | None | 0.1461 | None | None | N | 0.261 | 0.226 | 0.437100570223 | gnomAD-4.0.0 | 1.36888E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79943E-06 | 0 | 0 |
| F/L | 6914 |
Ig-53 |
61 | rs397517495 |
0.6126 | -1.394 | None | N | 0.317 | 0.129 | 0.311079019809 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| F/L | 6914 |
Ig-53 |
61 | rs397517495 |
0.6126 | -1.394 | None | N | 0.317 | 0.129 | 0.311079019809 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| F/L | 6914 |
Ig-53 |
61 | rs397517495 |
0.6126 | -1.394 | None | N | 0.317 | 0.129 | 0.311079019809 | gnomAD-4.0.0 | 1.36396E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.8653E-05 | 0 | 0 |
| I/F | 7007 |
Ig-54 |
60 | rs114626713 |
0.2578 | -1.91 | 1.0 | N | 0.803 | 0.586 | None | gnomAD-2.1.1 | 1.52088E-03 | None | None | None | None | N | None | 1.67866E-02 | 4.24785E-04 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 2.34E-05 | 1.40568E-04 |
| I/F | 7007 |
Ig-54 |
60 | rs114626713 |
0.2578 | -1.91 | 1.0 | N | 0.803 | 0.586 | None | gnomAD-3.1.2 | 4.51493E-03 | None | None | None | None | N | None | 1.61376E-02 | 5.89468E-04 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 3.34288E-03 |
| I/F | 7007 |
Ig-54 |
60 | rs114626713 |
0.2578 | -1.91 | 1.0 | N | 0.803 | 0.586 | None | 1000 genomes | 3.99361E-03 | None | None | None | None | N | None | 1.51E-02 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/F | 7007 |
Ig-54 |
60 | rs114626713 |
0.2578 | -1.91 | 1.0 | N | 0.803 | 0.586 | None | gnomAD-4.0.0 | 8.13706E-04 | None | None | None | None | N | None | 1.60082E-02 | 4.8343E-04 | None | 0 | 0 | None | 0 | 3.3036E-04 | 5.93404E-06 | 3.2941E-05 | 1.13666E-03 |
| I/T | 7007 |
Ig-54 |
60 | rs773611280 |
0.9715 | -3.553 | 1.0 | D | 0.813 | 0.828 | 0.856322546766 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.12E-05 | 0 |
| I/T | 7007 |
Ig-54 |
60 | rs773611280 |
0.9715 | -3.553 | 1.0 | D | 0.813 | 0.828 | 0.856322546766 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| I/T | 7007 |
Ig-54 |
60 | rs773611280 |
0.9715 | -3.553 | 1.0 | D | 0.813 | 0.828 | 0.856322546766 | gnomAD-4.0.0 | 2.60315E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.47567E-05 | 0 | 1.60149E-05 |
| L/M | 7103 |
Ig-55 |
60 | rs1235519093 |
0.138 | -1.765 | 0.454 | N | 0.43 | 0.111 | 0.421184727016 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| L/M | 7103 |
Ig-55 |
60 | rs1235519093 |
0.138 | -1.765 | 0.454 | N | 0.43 | 0.111 | 0.421184727016 | gnomAD-4.0.0 | 2.73728E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.5984E-06 | 0 | 0 |
| L/V | 7103 |
Ig-55 |
60 | None | 0.0897 | None | 0.005 | N | 0.309 | 0.078 | 0.190952846119 | gnomAD-4.0.0 | 6.84319E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99601E-07 | 0 | 0 |
| I/M | 7289 |
Ig-57 |
60 | None | 0.2185 | None | 0.81 | D | 0.642 | 0.616 | 0.709904841857 | gnomAD-4.0.0 | 6.84322E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99564E-07 | 0 | 0 |
| I/M | 7478 |
Ig-59 |
60 | None | 0.2348 | None | 0.935 | D | 0.703 | 0.641 | 0.68019974778 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| I/N | 7478 |
Ig-59 |
60 | None | 0.9321 | None | 1.0 | D | 0.892 | 0.768 | 0.918946889605 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/S | 7478 |
Ig-59 |
60 | rs912873564 |
0.9635 | None | 0.999 | D | 0.842 | 0.752 | 0.928535201343 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 7478 |
Ig-59 |
60 | rs912873564 |
0.9635 | None | 0.999 | D | 0.842 | 0.752 | 0.928535201343 | gnomAD-4.0.0 | 6.57644E-06 | None | None | None | None | N | None | 2.41453E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 7478 |
Ig-59 |
60 | rs1191020503 |
0.2508 | -2.125 | 0.425 | D | 0.352 | 0.401 | 0.702337487306 | gnomAD-2.1.1 | 9.56E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.94477E-04 | 0 |
| I/V | 7478 |
Ig-59 |
60 | rs1191020503 |
0.2508 | -2.125 | 0.425 | D | 0.352 | 0.401 | 0.702337487306 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| I/V | 7478 |
Ig-59 |
60 | rs1191020503 |
0.2508 | -2.125 | 0.425 | D | 0.352 | 0.401 | 0.702337487306 | gnomAD-4.0.0 | 6.19901E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47797E-06 | 0 | 0 |
| I/V | 7574 |
Ig-60 |
60 | rs1017841481 |
0.1259 | -1.727 | 0.011 | D | 0.248 | 0.345 | 0.558422169324 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 7574 |
Ig-60 |
60 | rs1017841481 |
0.1259 | -1.727 | 0.011 | D | 0.248 | 0.345 | 0.558422169324 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.23E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 7574 |
Ig-60 |
60 | rs1017841481 |
0.1259 | -1.727 | 0.011 | D | 0.248 | 0.345 | 0.558422169324 | gnomAD-4.0.0 | 4.05965E-06 | None | None | None | None | N | None | 6.98666E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 7761 |
Ig-62 |
60 | None | 0.9817 | None | 0.973 | D | 0.725 | 0.882 | 0.846497674913 | gnomAD-4.0.0 | 1.68046E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.83751E-05 | 0 | 0 |
| L/V | 7855 |
Ig-63 |
61 | rs1364646771 |
0.1172 | -1.444 | 0.001 | N | 0.279 | 0.096 | 0.260249123532 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 1.17924E-03 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/V | 7855 |
Ig-63 |
61 | rs1364646771 |
0.1172 | -1.444 | 0.001 | N | 0.279 | 0.096 | 0.260249123532 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 7855 |
Ig-63 |
61 | rs1364646771 |
0.1172 | -1.444 | 0.001 | N | 0.279 | 0.096 | 0.260249123532 | gnomAD-4.0.0 | 2.56253E-06 | None | None | None | None | N | None | 0 | 1.69503E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84527E-05 |
| I/V | 8230 |
Ig-67 |
60 | None | 0.1589 | None | 0.002 | D | 0.291 | 0.383 | 0.631027719221 | gnomAD-4.0.0 | 1.5913E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88253E-05 | 0 | 0 | 0 | 0 |
| M/I | 8609 |
Ig-71 |
61 | rs1407524421 |
0.3643 | None | None | N | 0.279 | 0.222 | 0.221019684889 | gnomAD-4.0.0 | 2.05282E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69863E-06 | 0 | 0 |
| M/V | 8609 |
Ig-71 |
61 | rs1369418506 |
0.2005 | None | None | N | 0.273 | 0.11 | 0.377274123778 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9305E-04 | None | 0 | 0 | 0 | 0 | 0 |
| M/V | 8609 |
Ig-71 |
61 | rs1369418506 |
0.2005 | None | None | N | 0.273 | 0.11 | 0.377274123778 | gnomAD-4.0.0 | 6.57445E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.9305E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 8702 |
Ig-72 |
60 | rs1560608555 |
0.1122 | None | 0.011 | D | 0.265 | 0.349 | 0.643072836008 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| I/V | 8702 |
Ig-72 |
60 | rs1560608555 |
0.1122 | None | 0.011 | D | 0.265 | 0.349 | 0.643072836008 | gnomAD-4.0.0 | 3.18287E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71772E-06 | 0 | 0 |
| F/C | 8796 |
Ig-73 |
61 | None | 0.2614 | None | 0.929 | N | 0.787 | 0.554 | 0.71030341735 | gnomAD-4.0.0 | 3.42113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49748E-06 | 0 | 0 |
| F/L | 8796 |
Ig-73 |
61 | rs1193918191 |
0.4696 | -0.784 | None | N | 0.3 | 0.135 | 0.213573922156 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| F/L | 8796 |
Ig-73 |
61 | rs1193918191 |
0.4696 | -0.784 | None | N | 0.3 | 0.135 | 0.213573922156 | gnomAD-4.0.0 | 1.59133E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8585E-06 | 0 | 0 |
| I/V | 8889 |
Ig-74 |
60 | rs879115210 |
0.1358 | None | 0.122 | D | 0.269 | 0.406 | None | gnomAD-4.0.0 | 3.60103E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.93759E-06 | 0 | 0 |
| L/F | 9078 |
Ig-76 |
60 | None | 0.2329 | None | 0.993 | N | 0.799 | 0.43 | 0.476832112026 | gnomAD-4.0.0 | 6.84223E-07 | None | None | None | None | N | None | 0 | 2.23684E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 9264 |
Ig-78 |
60 | None | 0.6586 | None | 0.999 | N | 0.839 | 0.665 | 0.8456673461 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/S | 9360 |
Ig-79 |
60 | rs745880964 |
0.9014 | -3.646 | 1.0 | None | 0.883 | 0.887 | 0.936186774989 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 1.13122E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/S | 9360 |
Ig-79 |
60 | rs745880964 |
0.9014 | -3.646 | 1.0 | None | 0.883 | 0.887 | 0.936186774989 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 9360 |
Ig-79 |
60 | rs745880964 |
0.9014 | -3.646 | 1.0 | None | 0.883 | 0.887 | 0.936186774989 | gnomAD-4.0.0 | 6.40467E-06 | None | None | None | None | N | None | 0 | 8.47285E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 9360 |
Ig-79 |
60 | rs2076598524 |
0.1502 | None | 0.993 | None | 0.389 | 0.473 | 0.771852621965 | gnomAD-4.0.0 | 6.84185E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99457E-06 | 0 | 0 |
| V/A | 9456 |
Ig-80 |
60 | rs1185144865 |
0.679 | -2.721 | 0.01 | None | 0.45 | 0.373 | 0.591201240261 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
| V/A | 9456 |
Ig-80 |
60 | rs1185144865 |
0.679 | -2.721 | 0.01 | None | 0.45 | 0.373 | 0.591201240261 | gnomAD-4.0.0 | 1.59117E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77254E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/F | 9456 |
Ig-80 |
60 | rs772549192 |
0.3632 | -1.738 | 0.055 | None | 0.661 | 0.247 | 0.607789150232 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| V/F | 9456 |
Ig-80 |
60 | rs772549192 |
0.3632 | -1.738 | 0.055 | None | 0.661 | 0.247 | 0.607789150232 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| V/I | 9553 |
Ig-81 |
61 | rs763879363 |
0.0766 | None | None | None | 0.256 | 0.064 | 0.202949470691 | gnomAD-4.0.0 | 2.7367E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59778E-06 | 0 | 0 |
| I/S | 9758 |
Ig-83 |
61 | None | 0.9961 | None | 1.0 | None | 0.872 | 0.835 | 0.871492119684 | gnomAD-4.0.0 | 2.05247E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69826E-06 | 0 | 0 |
| I/V | 9758 |
Ig-83 |
61 | None | 0.4705 | None | 0.993 | None | 0.399 | 0.469 | 0.708901879958 | gnomAD-4.0.0 | 1.59097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 0 | 0 | 0 |
| V/I | 9960 |
Ig-84 |
61 | None | 0.0823 | None | None | None | 0.245 | 0.055 | 0.247322355667 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| I/T | 10047 |
Ig-85 |
59 | rs1468010768 |
0.9484 | None | 1.0 | None | 0.827 | 0.804 | 0.865251336291 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| I/M | 13745 |
Ig-87 |
62 | None | 0.6339 | None | 1.0 | D | 0.748 | 0.573 | 0.666729369348 | gnomAD-4.0.0 | 6.84346E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15947E-05 | 0 |
| I/V | 13745 |
Ig-87 |
62 | rs770466417 |
0.2797 | -1.607 | 0.993 | D | 0.392 | 0.479 | 0.801257991606 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63452E-04 | None | 0 | 0 | 0 |
| I/V | 13745 |
Ig-87 |
62 | rs770466417 |
0.2797 | -1.607 | 0.993 | D | 0.392 | 0.479 | 0.801257991606 | gnomAD-4.0.0 | 1.02651E-05 | None | None | None | None | N | None | 2.98882E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99598E-07 | 1.50732E-04 | 0 |
| I/M | 13839 |
Ig-88 |
60 | None | 0.4357 | None | 0.968 | N | 0.734 | 0.27 | 0.370240404367 | gnomAD-4.0.0 | 1.36883E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79932E-06 | 0 | 0 |
| I/N | 13839 |
Ig-88 |
60 | None | 0.9857 | None | 0.995 | D | 0.831 | 0.5 | 0.546780063783 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| I/V | 13839 |
Ig-88 |
60 | rs1433829695 |
0.1366 | -1.537 | 0.026 | N | 0.25 | 0.147 | 0.263140351381 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| I/V | 13839 |
Ig-88 |
60 | rs1433829695 |
0.1366 | -1.537 | 0.026 | N | 0.25 | 0.147 | 0.263140351381 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 13839 |
Ig-88 |
60 | rs1433829695 |
0.1366 | -1.537 | 0.026 | N | 0.25 | 0.147 | 0.263140351381 | gnomAD-4.0.0 | 3.71927E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23893E-06 | 0 | 1.60143E-05 |
| M/R | 14200 |
Ig-92 |
59 | None | 0.8246 | None | 0.106 | N | 0.719 | 0.529 | 0.635165634531 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/L | 14555 |
Ig-96 |
59 | rs1452980014 |
0.8584 | -0.643 | 0.002 | N | 0.309 | 0.215 | 0.459463830659 | gnomAD-2.1.1 | 4.2E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.72771E-04 |
| L/S | 14733 |
Ig-98 |
59 | None | 0.9841 | None | 0.999 | D | 0.879 | 0.526 | 0.730100223331 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/R | 14822 |
Ig-99 |
58 | rs1235710023 |
0.8163 | -1.253 | 0.999 | D | 0.82 | 0.692 | 0.85728530589 | gnomAD-2.1.1 | 4.26E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.23E-06 | 0 |
| L/R | 14822 |
Ig-99 |
58 | rs1235710023 |
0.8163 | -1.253 | 0.999 | D | 0.82 | 0.692 | 0.85728530589 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/R | 14822 |
Ig-99 |
58 | rs1235710023 |
0.8163 | -1.253 | 0.999 | D | 0.82 | 0.692 | 0.85728530589 | gnomAD-4.0.0 | 3.92008E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.28116E-06 | 0 | 0 |
| I/K | 14911 |
Ig-100 |
59 | rs754905274 |
0.9847 | -2.611 | 0.999 | D | 0.821 | 0.837 | 0.939999114054 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/K | 14911 |
Ig-100 |
59 | rs754905274 |
0.9847 | -2.611 | 0.999 | D | 0.821 | 0.837 | 0.939999114054 | gnomAD-4.0.0 | 1.59342E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4332E-05 | 0 |
| I/M | 14911 |
Ig-100 |
59 | rs751425454 |
0.4391 | -1.48 | 0.998 | D | 0.665 | 0.612 | 0.73347288092 | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.61489E-04 | None | 0 | 0 | 0 |
| I/M | 14911 |
Ig-100 |
59 | rs751425454 |
0.4391 | -1.48 | 0.998 | D | 0.665 | 0.612 | 0.73347288092 | gnomAD-4.0.0 | 1.43767E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.43523E-04 | 0 |
| I/T | 14911 |
Ig-100 |
59 | rs754905274 |
0.9686 | -3.419 | 0.989 | D | 0.724 | 0.722 | 0.876608931427 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 14911 |
Ig-100 |
59 | rs754905274 |
0.9686 | -3.419 | 0.989 | D | 0.724 | 0.722 | 0.876608931427 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 14911 |
Ig-100 |
59 | rs754905274 |
0.9686 | -3.419 | 0.989 | D | 0.724 | 0.722 | 0.876608931427 | gnomAD-4.0.0 | 6.57921E-06 | None | None | None | None | N | None | 2.41348E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 15000 |
Ig-101 |
59 | rs886055275 |
0.9625 | None | 0.722 | D | 0.684 | 0.727 | 0.807264362512 | gnomAD-4.0.0 | 1.59515E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03269E-05 |
| I/V | 15000 |
Ig-101 |
59 | rs775264673 |
0.1615 | -1.719 | 0.001 | D | 0.289 | 0.192 | 0.534719010399 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 15000 |
Ig-101 |
59 | rs775264673 |
0.1615 | -1.719 | 0.001 | D | 0.289 | 0.192 | 0.534719010399 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 15000 |
Ig-101 |
59 | rs775264673 |
0.1615 | -1.719 | 0.001 | D | 0.289 | 0.192 | 0.534719010399 | gnomAD-4.0.0 | 6.57981E-06 | None | None | None | None | N | None | 2.41371E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 15089 |
Ig-102 |
59 | None | 0.9604 | None | 0.989 | D | 0.757 | 0.747 | 0.901871528509 | gnomAD-4.0.0 | 1.59375E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43332E-05 | 0 |
| I/N | 15266 |
Ig-104 |
59 | rs1214768698 |
0.967 | -3.058 | 0.681 | D | 0.861 | 0.751 | 0.805582790611 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| I/N | 15266 |
Ig-104 |
59 | rs1214768698 |
0.967 | -3.058 | 0.681 | D | 0.861 | 0.751 | 0.805582790611 | gnomAD-4.0.0 | 1.59328E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77747E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 15360 |
Ig-105 |
59 | rs746352388 |
0.3937 | -1.467 | 0.998 | D | 0.685 | 0.614 | 0.666064869456 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| I/M | 15360 |
Ig-105 |
59 | rs746352388 |
0.3937 | -1.467 | 0.998 | D | 0.685 | 0.614 | 0.666064869456 | gnomAD-4.0.0 | 3.18877E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72849E-06 | 0 | 0 |
| I/T | 15360 |
Ig-105 |
59 | rs1465320800 |
0.9687 | -3.013 | 0.989 | D | 0.755 | 0.76 | 0.844994757482 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.14E-05 | 0 |
| I/T | 15360 |
Ig-105 |
59 | rs1465320800 |
0.9687 | -3.013 | 0.989 | D | 0.755 | 0.76 | 0.844994757482 | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| I/T | 15360 |
Ig-105 |
59 | rs1465320800 |
0.9687 | -3.013 | 0.989 | D | 0.755 | 0.76 | 0.844994757482 | gnomAD-4.0.0 | 1.92282E-05 | None | None | None | None | N | None | 1.33711E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54473E-05 | 0 | 0 |
| I/V | 15360 |
Ig-105 |
59 | rs758542642 |
0.1462 | -1.454 | 0.333 | D | 0.263 | 0.425 | 0.717905595574 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 15360 |
Ig-105 |
59 | rs758542642 |
0.1462 | -1.454 | 0.333 | D | 0.263 | 0.425 | 0.717905595574 | gnomAD-4.0.0 | 1.59436E-06 | None | None | None | None | N | None | 0 | 2.29085E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 16318 |
Ig-110 |
57 | rs962564634 |
0.3612 | None | 0.889 | D | 0.415 | 0.489 | 0.721054117171 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| I/L | 16318 |
Ig-110 |
57 | rs962564634 |
0.3612 | None | 0.889 | D | 0.415 | 0.489 | 0.721054117171 | gnomAD-4.0.0 | 1.31709E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94594E-05 | 0 | 0 |
| I/T | 16318 |
Ig-110 |
57 | rs72677243 |
0.9089 | -2.811 | 0.989 | D | 0.753 | 0.748 | None | gnomAD-2.1.1 | 1.17164E-03 | None | None | None | None | N | None | 1.24131E-04 | 1.10726E-03 | None | 1.02693E-02 | 5.2E-05 | None | 4.25142E-04 | None | 8.01E-05 | 1.19961E-03 | 1.41084E-03 |
| I/T | 16318 |
Ig-110 |
57 | rs72677243 |
0.9089 | -2.811 | 0.989 | D | 0.753 | 0.748 | None | gnomAD-3.1.2 | 9.55242E-04 | None | None | None | None | N | None | 2.41663E-04 | 7.8854E-04 | 0 | 1.09763E-02 | 0 | None | 0 | 9.49367E-03 | 1.10463E-03 | 4.16667E-04 | 2.39693E-03 |
| I/T | 16318 |
Ig-110 |
57 | rs72677243 |
0.9089 | -2.811 | 0.989 | D | 0.753 | 0.748 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 8E-04 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/T | 16318 |
Ig-110 |
57 | rs72677243 |
0.9089 | -2.811 | 0.989 | D | 0.753 | 0.748 | None | gnomAD-4.0.0 | 1.02707E-03 | None | None | None | None | N | None | 2.40327E-04 | 1.08579E-03 | None | 9.70907E-03 | 0 | None | 4.69087E-05 | 1.65344E-03 | 9.66821E-04 | 5.82341E-04 | 1.28201E-03 |
| I/V | 16318 |
Ig-110 |
57 | rs962564634 |
0.0992 | -1.651 | 0.333 | D | 0.235 | 0.358 | 0.678242657409 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/V | 16318 |
Ig-110 |
57 | rs962564634 |
0.0992 | -1.651 | 0.333 | D | 0.235 | 0.358 | 0.678242657409 | gnomAD-4.0.0 | 3.42363E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79979E-06 | 3.47987E-05 | 0 |
| V/A | 17336 |
Ig-112 |
86 | rs1315720730 |
0.8524 | -1.922 | 0.052 | N | 0.598 | 0.531 | 0.493156425868 | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.47E-05 | None | 0 | 0 | 0 |
| V/A | 17336 |
Ig-112 |
86 | rs1315720730 |
0.8524 | -1.922 | 0.052 | N | 0.598 | 0.531 | 0.493156425868 | gnomAD-4.0.0 | 1.6174E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.47033E-05 | 0 |
| V/I | 17336 |
Ig-112 |
86 | rs567781604 |
0.0685 | -0.844 | 0.001 | N | 0.215 | 0.101 | 0.177238962908 | gnomAD-2.1.1 | 4.78E-05 | None | None | None | None | N | None | 4.16E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.62E-05 | 0 |
| V/I | 17336 |
Ig-112 |
86 | rs567781604 |
0.0685 | -0.844 | 0.001 | N | 0.215 | 0.101 | 0.177238962908 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 2.07383E-04 | 4.78469E-04 |
| V/I | 17336 |
Ig-112 |
86 | rs567781604 |
0.0685 | -0.844 | 0.001 | N | 0.215 | 0.101 | 0.177238962908 | gnomAD-4.0.0 | 5.0526E-05 | None | None | None | None | N | None | 2.68861E-05 | 3.39732E-05 | None | 0 | 0 | None | 6.29247E-05 | 0 | 5.70352E-05 | 1.12075E-05 | 8.06894E-05 |
| I/N | 17731 |
Ig-113 |
55 | rs72646809 |
0.9607 | -2.899 | 1.0 | D | 0.901 | 0.846 | 0.93495532163 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/N | 17731 |
Ig-113 |
55 | rs72646809 |
0.9607 | -2.899 | 1.0 | D | 0.901 | 0.846 | 0.93495532163 | gnomAD-4.0.0 | 1.36878E-06 | None | None | None | None | N | None | 5.98193E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 17731 |
Ig-113 |
55 | rs72646809 |
0.9513 | -3.166 | 1.0 | D | 0.834 | 0.801 | None | gnomAD-2.1.1 | 1.37245E-02 | None | None | None | None | N | None | 2.19117E-03 | 6.84389E-03 | None | 3.00483E-02 | 5.13E-05 | None | 9.41238E-03 | None | 4.10105E-02 | 1.4082E-02 | 1.69896E-02 |
| I/T | 17731 |
Ig-113 |
55 | rs72646809 |
0.9513 | -3.166 | 1.0 | D | 0.834 | 0.801 | None | gnomAD-3.1.2 | 1.10997E-02 | None | None | None | None | N | None | 2.51014E-03 | 4.72007E-03 | 3.28947E-03 | 3.60438E-02 | 0 | None | 4.71165E-02 | 2.21519E-02 | 1.1924E-02 | 8.27472E-03 | 1.24283E-02 |
| I/T | 17731 |
Ig-113 |
55 | rs72646809 |
0.9513 | -3.166 | 1.0 | D | 0.834 | 0.801 | None | 1000 genomes | 4.59265E-03 | None | None | None | None | N | None | 0 | 2.9E-03 | None | None | 0 | 1.79E-02 | None | None | None | 3.1E-03 | None |
| I/T | 17731 |
Ig-113 |
55 | rs72646809 |
0.9513 | -3.166 | 1.0 | D | 0.834 | 0.801 | None | gnomAD-4.0.0 | 1.1447E-02 | None | None | None | None | N | None | 2.21369E-03 | 6.61777E-03 | None | 3.08634E-02 | 2.23204E-05 | None | 3.96176E-02 | 1.33796E-02 | 1.0875E-02 | 9.00386E-03 | 1.15944E-02 |
| I/V | 17731 |
Ig-113 |
55 | None | 0.1641 | None | 0.993 | D | 0.397 | 0.455 | 0.77874929467 | gnomAD-4.0.0 | 1.59225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86062E-06 | 0 | 0 |
| I/T | 18032 |
Ig-114 |
65 | None | 0.9339 | None | 0.896 | D | 0.81 | 0.844 | 0.818036558674 | gnomAD-4.0.0 | 1.59341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02828E-05 |
| I/V | 18032 |
Ig-114 |
65 | rs1227589199 |
0.1524 | -1.488 | 0.437 | D | 0.421 | 0.522 | 0.528860544761 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 18032 |
Ig-114 |
65 | rs1227589199 |
0.1524 | -1.488 | 0.437 | D | 0.421 | 0.522 | 0.528860544761 | gnomAD-4.0.0 | 3.1867E-06 | None | None | None | None | N | None | 0 | 4.57498E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/F | 18751 |
Ig-116 |
64 | None | 0.4372 | None | 0.998 | D | 0.721 | 0.836 | 0.816700955439 | gnomAD-4.0.0 | 2.05369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73792E-04 | 0 | 2.32213E-05 | 0 |
| I/M | 19150 |
Ig-117 |
56 | rs2052065992 |
0.3549 | None | 1.0 | D | 0.754 | 0.694 | 0.750852903986 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/M | 19150 |
Ig-117 |
56 | rs2052065992 |
0.3549 | None | 1.0 | D | 0.754 | 0.694 | 0.750852903986 | gnomAD-4.0.0 | 6.57739E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47115E-05 | 0 | 0 |
| I/T | 19150 |
Ig-117 |
56 | rs1553659483 |
0.9841 | None | 1.0 | D | 0.804 | 0.781 | 0.845731052345 | gnomAD-4.0.0 | 3.18484E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71997E-06 | 0 | 0 |
| K/E | 19446 |
Ig-118 |
56 | None | 0.527 | None | 0.425 | N | 0.477 | 0.204 | 0.39709148275 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 19446 |
Ig-118 |
56 | rs536286313 |
0.5583 | -1.036 | 0.01 | N | 0.271 | 0.137 | 0.162503812791 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/N | 19446 |
Ig-118 |
56 | rs536286313 |
0.5583 | -1.036 | 0.01 | N | 0.271 | 0.137 | 0.162503812791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 19446 |
Ig-118 |
56 | rs536286313 |
0.5583 | -1.036 | 0.01 | N | 0.271 | 0.137 | 0.162503812791 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| K/N | 19446 |
Ig-118 |
56 | rs536286313 |
0.5583 | -1.036 | 0.01 | N | 0.271 | 0.137 | 0.162503812791 | gnomAD-4.0.0 | 6.57022E-06 | None | None | None | None | N | None | 2.40616E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/N | 20138 |
Ig-120 |
59 | rs762525368 |
0.962 | -3.117 | 0.997 | D | 0.885 | 0.748 | 0.931505991749 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| I/N | 20138 |
Ig-120 |
59 | rs762525368 |
0.962 | -3.117 | 0.997 | D | 0.885 | 0.748 | 0.931505991749 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/N | 20138 |
Ig-120 |
59 | rs762525368 |
0.962 | -3.117 | 0.997 | D | 0.885 | 0.748 | 0.931505991749 | gnomAD-4.0.0 | 3.40949E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.57833E-05 | 0 | 1.60143E-05 |
| I/T | 20138 |
Ig-120 |
59 | rs762525368 |
0.9596 | None | 0.991 | D | 0.772 | 0.79 | 0.89323557897 | gnomAD-4.0.0 | 6.84393E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51953E-05 | None | 0 | 0 | 0 | 0 | 0 |
| L/R | 20831 |
Ig-122 |
63 | None | 0.8256 | None | 1.0 | N | 0.893 | 0.622 | 0.71338130811 | gnomAD-4.0.0 | 1.59183E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43291E-05 | 0 |
| I/M | 21233 |
Ig-123 |
57 | None | 0.4145 | None | 1.0 | D | 0.783 | 0.651 | 0.704424639576 | gnomAD-4.0.0 | 6.84706E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99751E-07 | 0 | 0 |
| I/T | 21233 |
Ig-123 |
57 | None | 0.9595 | None | 1.0 | D | 0.823 | 0.782 | 0.873723102753 | gnomAD-4.0.0 | 6.84678E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99743E-07 | 0 | 0 |
| I/T | 21526 |
Ig-124 |
58 | rs776476433 |
0.9448 | -3.335 | 0.324 | D | 0.703 | 0.679 | 0.826635456628 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.7E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 21526 |
Ig-124 |
58 | rs776476433 |
0.9448 | -3.335 | 0.324 | D | 0.703 | 0.679 | 0.826635456628 | gnomAD-4.0.0 | 3.42188E-06 | None | None | None | None | N | None | 0 | 6.70871E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 2.3197E-05 | 0 |
| I/V | 21526 |
Ig-124 |
58 | rs1160431016 |
0.1653 | -1.857 | 0.001 | D | 0.259 | 0.325 | 0.643445338908 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.97E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 21526 |
Ig-124 |
58 | rs1160431016 |
0.1653 | -1.857 | 0.001 | D | 0.259 | 0.325 | 0.643445338908 | gnomAD-4.0.0 | 1.59227E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76963E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 22610 |
Ig-127 |
51 | None | 0.3751 | None | 0.994 | N | 0.667 | 0.348 | 0.68758794608 | gnomAD-4.0.0 | 3.18377E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71922E-06 | 0 | 0 |
| I/T | 23007 |
Ig-128 |
58 | rs1366649624 |
0.6856 | -2.786 | 0.124 | D | 0.702 | 0.732 | 0.78812575404 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 23007 |
Ig-128 |
58 | rs1366649624 |
0.6856 | -2.786 | 0.124 | D | 0.702 | 0.732 | 0.78812575404 | gnomAD-4.0.0 | 1.5921E-06 | None | None | None | None | N | None | 0 | 2.28707E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 23007 |
Ig-128 |
58 | rs750858964 |
0.0727 | -1.597 | None | D | 0.276 | 0.327 | 0.321393169273 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| I/V | 23007 |
Ig-128 |
58 | rs750858964 |
0.0727 | -1.597 | None | D | 0.276 | 0.327 | 0.321393169273 | gnomAD-4.0.0 | 3.18417E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41313E-04 | 2.85971E-06 | 0 | 0 |
| I/T | 23402 |
Ig-129 |
58 | None | 0.9358 | None | 0.014 | D | 0.554 | 0.708 | 0.790246465493 | gnomAD-4.0.0 | 2.73739E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59868E-06 | 0 | 0 |
| I/M | 23693 |
Ig-130 |
57 | None | 0.205 | None | 0.998 | D | 0.691 | 0.574 | 0.73377832567 | gnomAD-4.0.0 | 2.05308E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69875E-06 | 0 | 0 |
| N/K | 24089 |
Ig-131 |
61 | None | 0.6802 | None | 0.684 | N | 0.668 | 0.201 | 0.212008924253 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| N/Y | 24089 |
Ig-131 |
61 | rs1709123437 |
0.2429 | None | 0.979 | N | 0.85 | 0.367 | 0.546607571196 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/Y | 24089 |
Ig-131 |
61 | rs1709123437 |
0.2429 | None | 0.979 | N | 0.85 | 0.367 | 0.546607571196 | gnomAD-4.0.0 | 2.57093E-06 | None | None | None | None | N | None | 3.38822E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 24775 |
Ig-133 |
60 | rs766089174 |
0.1227 | -1.623 | 0.103 | D | 0.3 | 0.464 | 0.639007618878 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| I/V | 24775 |
Ig-133 |
60 | rs766089174 |
0.1227 | -1.623 | 0.103 | D | 0.3 | 0.464 | 0.639007618878 | gnomAD-4.0.0 | 9.58031E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25941E-05 | 0 | 0 |
| V/I | 25171 |
Ig-134 |
61 | None | 0.0788 | None | 0.025 | N | 0.332 | 0.061 | 0.162503812791 | gnomAD-4.0.0 | 1.59191E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85925E-06 | 0 | 0 |
| L/P | 25568 |
Ig-135 |
55 | None | 0.9815 | None | 0.994 | N | 0.855 | 0.778 | 0.87689326119 | gnomAD-4.0.0 | 1.36885E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79927E-06 | 0 | 0 |
| I/N | 25857 |
Ig-136 |
60 | rs781755787 |
0.9598 | -2.663 | 0.997 | D | 0.867 | 0.794 | 0.935398395153 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11495E-04 | None | 0 | None | 0 | 0 | 0 |
| I/N | 25857 |
Ig-136 |
60 | rs781755787 |
0.9598 | -2.663 | 0.997 | D | 0.867 | 0.794 | 0.935398395153 | gnomAD-4.0.0 | 1.36867E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.04185E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 25857 |
Ig-136 |
60 | None | 0.9394 | None | 0.991 | D | 0.771 | 0.797 | 0.870264459797 | gnomAD-4.0.0 | 6.84333E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.1595E-05 | 0 |
| I/V | 25857 |
Ig-136 |
60 | rs878865219 |
0.1095 | None | 0.58 | D | 0.4 | 0.466 | None | gnomAD-4.0.0 | 4.10596E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39764E-06 | 0 | 0 |
| I/V | 26650 |
Ig-138 |
57 | None | 0.0998 | None | 0.333 | D | 0.237 | 0.459 | 0.514472708086 | gnomAD-4.0.0 | 3.42128E-06 | None | None | None | None | N | None | 2.989E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6986E-06 | 1.15937E-05 | 0 |
| I/N | 26939 |
Ig-139 |
60 | rs1705331466 |
0.9643 | None | 0.975 | D | 0.853 | 0.827 | 0.921599369569 | gnomAD-4.0.0 | 1.36853E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.03931E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 26939 |
Ig-139 |
60 | rs1705331466 |
0.9541 | None | 0.645 | D | 0.763 | 0.825 | 0.839350010842 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/T | 26939 |
Ig-139 |
60 | rs1705331466 |
0.9541 | None | 0.645 | D | 0.763 | 0.825 | 0.839350010842 | gnomAD-4.0.0 | 3.71873E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08619E-06 | 0 | 0 |
| I/F | 27733 |
Ig-141 |
58 | rs1393748586 |
0.6127 | -1.622 | 0.998 | D | 0.713 | 0.76 | 0.835424349326 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65782E-04 |
| I/F | 27733 |
Ig-141 |
58 | rs1393748586 |
0.6127 | -1.622 | 0.998 | D | 0.713 | 0.76 | 0.835424349326 | gnomAD-4.0.0 | 1.59169E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02517E-05 |
| I/L | 27733 |
Ig-141 |
58 | None | 0.195 | None | 0.889 | D | 0.479 | 0.606 | 0.760994400293 | gnomAD-4.0.0 | 1.59169E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02517E-05 |
| I/T | 27733 |
Ig-141 |
58 | rs759928014 |
0.4989 | -1.753 | 0.989 | D | 0.757 | 0.807 | 0.891955713682 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | I | None | 0 | 5.81E-05 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 8.9E-06 | 0 |
| I/T | 27733 |
Ig-141 |
58 | rs759928014 |
0.4989 | -1.753 | 0.989 | D | 0.757 | 0.807 | 0.891955713682 | gnomAD-4.0.0 | 3.48986E-05 | None | None | None | None | I | None | 0 | 6.71081E-05 | None | 0 | 0 | None | 0 | 0 | 4.04775E-05 | 3.4781E-05 | 0 |
| V/A | 28417 |
Ig-143 |
60 | None | 0.6636 | None | 0.892 | D | 0.612 | 0.608 | 0.729265719692 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 6.07533E-05 | 0 |
| I/T | 28812 |
Ig-144 |
58 | rs727504959 |
0.4998 | -1.291 | 0.124 | D | 0.795 | 0.755 | 0.757070926547 | gnomAD-2.1.1 | 1.65E-05 | None | None | None | None | N | None | 0 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 4.8E-05 | 1.82E-05 | 0 |
| I/T | 28812 |
Ig-144 |
58 | rs727504959 |
0.4998 | -1.291 | 0.124 | D | 0.795 | 0.755 | 0.757070926547 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| I/T | 28812 |
Ig-144 |
58 | rs727504959 |
0.4998 | -1.291 | 0.124 | D | 0.795 | 0.755 | 0.757070926547 | gnomAD-4.0.0 | 1.80386E-05 | None | None | None | None | N | None | 0 | 1.67785E-05 | None | 0 | 0 | None | 7.86015E-05 | 0 | 1.69967E-05 | 0 | 4.82191E-05 |
| I/V | 28812 |
Ig-144 |
58 | rs201918596 |
0.0609 | -0.993 | 0.001 | D | 0.357 | 0.229 | None | gnomAD-2.1.1 | 2.37328E-04 | None | None | None | None | N | None | 2.60999E-03 | 2.86E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.44051E-04 |
| I/V | 28812 |
Ig-144 |
58 | rs201918596 |
0.0609 | -0.993 | 0.001 | D | 0.357 | 0.229 | None | gnomAD-3.1.2 | 6.899E-04 | None | None | None | None | N | None | 2.48492E-03 | 1.30941E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 28812 |
Ig-144 |
58 | rs201918596 |
0.0609 | -0.993 | 0.001 | D | 0.357 | 0.229 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 3.8E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/V | 28812 |
Ig-144 |
58 | rs201918596 |
0.0609 | -0.993 | 0.001 | D | 0.357 | 0.229 | None | gnomAD-4.0.0 | 1.27505E-04 | None | None | None | None | N | None | 2.62996E-03 | 5.03389E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 8.03626E-05 |
| I/L | 29500 |
Ig-146 |
57 | rs761934380 |
0.1752 | -0.954 | 0.005 | D | 0.299 | 0.374 | 0.585808247695 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.30745E-04 | None | 0 | 0 | 0 |
| I/L | 29500 |
Ig-146 |
57 | rs761934380 |
0.1752 | -0.954 | 0.005 | D | 0.299 | 0.374 | 0.585808247695 | gnomAD-4.0.0 | 7.52669E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9946E-07 | 9.27472E-05 | 3.31334E-05 |
| I/M | 29500 |
Ig-146 |
57 | None | 0.2036 | None | 0.976 | D | 0.697 | 0.749 | 0.716492818265 | gnomAD-4.0.0 | 6.84265E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99493E-07 | 0 | 0 |
| I/T | 30191 |
Ig-148 |
60 | None | 0.9332 | None | 0.961 | D | 0.717 | 0.762 | 0.856007427658 | gnomAD-4.0.0 | 2.06318E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.8033E-06 | 1.18751E-05 | 0 |
| I/V | 30191 |
Ig-148 |
60 | rs746824077 |
0.1176 | -1.605 | 0.122 | D | 0.286 | 0.382 | 0.541512316009 | gnomAD-2.1.1 | 1.11E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 7.22E-05 | None | 0 | 8E-06 | 0 |
| I/V | 30191 |
Ig-148 |
60 | rs746824077 |
0.1176 | -1.605 | 0.122 | D | 0.286 | 0.382 | 0.541512316009 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 30191 |
Ig-148 |
60 | rs746824077 |
0.1176 | -1.605 | 0.122 | D | 0.286 | 0.382 | 0.541512316009 | gnomAD-4.0.0 | 3.11628E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.50011E-07 | 4.51101E-05 | 0 |
| V/A | 31275 |
Ig-151 |
58 | None | 0.6051 | None | 0.002 | N | 0.375 | 0.397 | 0.506734346222 | gnomAD-4.0.0 | 1.59111E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88246E-05 | 0 | 0 | 0 | 0 |
| V/I | 31275 |
Ig-151 |
58 | rs1287511397 |
0.097 | -0.659 | 0.002 | N | 0.343 | 0.058 | 0.165133752707 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| V/I | 31275 |
Ig-151 |
58 | rs1287511397 |
0.097 | -0.659 | 0.002 | N | 0.343 | 0.058 | 0.165133752707 | gnomAD-4.0.0 | 1.59114E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85789E-06 | 0 | 0 |
| V/L | 31275 |
Ig-151 |
58 | None | 0.3308 | None | 0.034 | N | 0.611 | 0.103 | 0.256793551483 | gnomAD-4.0.0 | 1.59114E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85789E-06 | 0 | 0 |
| I/T | 31675 |
Ig-152 |
55 | None | 0.9378 | None | 0.939 | D | 0.749 | 0.853 | 0.837465136938 | gnomAD-4.0.0 | 1.59123E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85832E-06 | 0 | 0 |
| V/G | 32072 |
Ig-153 |
56 | None | 0.8627 | None | 0.971 | D | 0.87 | 0.696 | 0.932966899989 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 32072 |
Ig-153 |
56 | rs1375176606 |
0.3166 | -0.612 | 0.247 | N | 0.523 | 0.237 | 0.365317461125 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 32072 |
Ig-153 |
56 | rs1375176606 |
0.3166 | -0.612 | 0.247 | N | 0.523 | 0.237 | 0.365317461125 | gnomAD-4.0.0 | 1.59139E-06 | None | None | None | None | N | None | 5.65867E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 32366 |
Ig-154 |
60 | rs1695213145 |
0.9447 | None | 0.991 | D | 0.828 | 0.885 | 0.938880340865 | gnomAD-4.0.0 | 1.59121E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85824E-06 | 0 | 0 |
| I/V | 32366 |
Ig-154 |
60 | rs1304811622 |
0.1056 | -1.848 | 0.02 | D | 0.259 | 0.354 | 0.538792235971 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| I/M | 32762 |
Ig-155 |
55 | rs794729550 |
0.2813 | None | 1.0 | D | 0.763 | 0.57 | 0.730747000282 | gnomAD-4.0.0 | 5.47355E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5194E-05 | None | 0 | 0 | 0 | 0 | 1.15955E-04 |
| I/N | 32762 |
Ig-155 |
55 | None | 0.9472 | None | 1.0 | D | 0.879 | 0.773 | 0.933577829633 | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8582E-06 | 0 | 0 |
| V/I | 33160 |
Ig-156 |
60 | rs794729553 |
0.0776 | None | 0.023 | N | 0.272 | 0.077 | 0.286081765059 | gnomAD-4.0.0 | 2.73691E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59789E-06 | 0 | 0 |
| V/L | 33160 |
Ig-156 |
60 | None | 0.3428 | None | 0.175 | N | 0.549 | 0.138 | 0.538283067721 | gnomAD-4.0.0 | 2.73691E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59789E-06 | 0 | 0 |
| M/I | 33256 |
Ig-157 |
54 | rs752102823 |
0.2287 | -1.18 | None | N | 0.271 | 0.117 | 0.282575091529 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 1.45994E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/I | 33256 |
Ig-157 |
54 | rs752102823 |
0.2287 | -1.18 | None | N | 0.271 | 0.117 | 0.282575091529 | gnomAD-4.0.0 | 7.96686E-06 | None | None | None | None | N | None | 0 | 1.14574E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/L | 33256 |
Ig-157 |
54 | rs755612464 |
0.1505 | -1.181 | None | N | 0.257 | 0.264 | 0.34854441366 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 6.51E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/L | 33256 |
Ig-157 |
54 | rs755612464 |
0.1505 | -1.181 | None | N | 0.257 | 0.264 | 0.34854441366 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/L | 33256 |
Ig-157 |
54 | rs755612464 |
0.1505 | -1.181 | None | N | 0.257 | 0.264 | 0.34854441366 | gnomAD-4.0.0 | 6.57004E-06 | None | None | None | None | N | None | 2.41243E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 33557 |
Ig-158 |
62 | rs771784438 |
0.4832 | -1.837 | 0.233 | D | 0.413 | 0.468 | 0.594650670498 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| I/T | 33557 |
Ig-158 |
62 | rs1007331943 |
0.9624 | -3.35 | 0.997 | D | 0.722 | 0.794 | 0.862868373484 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| I/T | 33557 |
Ig-158 |
62 | rs1007331943 |
0.9624 | -3.35 | 0.997 | D | 0.722 | 0.794 | 0.862868373484 | gnomAD-4.0.0 | 1.99117E-05 | None | None | None | None | N | None | 2.99796E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.52657E-05 | 0 | 0 |
| F/L | 33655 |
Ig-159 |
60 | rs984242810 |
0.9866 | None | 1.0 | N | 0.627 | 0.558 | 0.600342123009 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 33655 |
Ig-159 |
60 | rs984242810 |
0.9866 | None | 1.0 | N | 0.627 | 0.558 | 0.600342123009 | gnomAD-4.0.0 | 3.71809E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08562E-06 | 0 | 0 |
| F/Y | 33655 |
Ig-159 |
60 | rs1032594285 |
0.8483 | -1.878 | 1.0 | D | 0.612 | 0.493 | 0.602748970639 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| F/Y | 33655 |
Ig-159 |
60 | rs1032594285 |
0.8483 | -1.878 | 1.0 | D | 0.612 | 0.493 | 0.602748970639 | gnomAD-4.0.0 | 1.59131E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77254E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 34196 |
Ig-160 |
60 | rs1185169765 |
0.0778 | None | None | N | 0.255 | 0.099 | 0.110078149338 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 34196 |
Ig-160 |
60 | rs1185169765 |
0.0778 | None | None | N | 0.255 | 0.099 | 0.110078149338 | gnomAD-4.0.0 | 2.47856E-06 | None | None | None | None | N | None | 1.33479E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54264E-06 | 0 | 0 |
| I/S | 34423 |
Ig-162 |
61 | rs756074712 |
0.9914 | -3.597 | 0.997 | D | 0.848 | 0.903 | 0.881115435736 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63388E-04 | None | 0 | 0 | 0 |
| I/S | 34423 |
Ig-162 |
61 | rs756074712 |
0.9914 | -3.597 | 0.997 | D | 0.848 | 0.903 | 0.881115435736 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| I/S | 34423 |
Ig-162 |
61 | rs756074712 |
0.9914 | -3.597 | 0.997 | D | 0.848 | 0.903 | 0.881115435736 | gnomAD-4.0.0 | 9.29617E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.64676E-04 | 0 |
| I/V | 34423 |
Ig-162 |
61 | rs777746298 |
0.2718 | -1.681 | 0.198 | D | 0.249 | 0.416 | 0.540606920606 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.68E-05 | 1.77E-05 | 0 |
| I/V | 34423 |
Ig-162 |
61 | rs777746298 |
0.2718 | -1.681 | 0.198 | D | 0.249 | 0.416 | 0.540606920606 | gnomAD-4.0.0 | 1.11413E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.78372E-05 | 0 | 1.14305E-05 | 0 | 3.02407E-05 |
| I/L | 35188 |
Ig-164 |
60 | rs727504491 |
0.2506 | -0.702 | 0.983 | D | 0.421 | 0.677 | 0.718028692739 | gnomAD-2.1.1 | 2.49E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.67E-05 | 1.40056E-04 |
| I/L | 35188 |
Ig-164 |
60 | rs727504491 |
0.2506 | -0.702 | 0.983 | D | 0.421 | 0.677 | 0.718028692739 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 4.41E-05 | 0 | 0 |
| I/L | 35188 |
Ig-164 |
60 | rs727504491 |
0.2506 | -0.702 | 0.983 | D | 0.421 | 0.677 | 0.718028692739 | gnomAD-4.0.0 | 2.54028E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.64962E-03 | 2.37312E-05 | 1.09791E-05 | 3.20061E-05 |
| I/M | 35188 |
Ig-164 |
60 | None | 0.2059 | None | 0.999 | D | 0.769 | 0.507 | 0.633405343067 | gnomAD-4.0.0 | 1.59089E-06 | None | None | None | None | N | None | 5.65291E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 35188 |
Ig-164 |
60 | rs764963502 |
0.9389 | -2.724 | 0.999 | D | 0.838 | 0.853 | 0.866247393669 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/T | 35188 |
Ig-164 |
60 | rs764963502 |
0.9389 | -2.724 | 0.999 | D | 0.838 | 0.853 | 0.866247393669 | gnomAD-4.0.0 | 3.18176E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
| I/M | 35346 |
Ig-165 |
61 | rs1688672739 |
0.2274 | None | 0.999 | D | 0.678 | 0.563 | 0.713815690768 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 35346 |
Ig-165 |
61 | rs1688672739 |
0.2274 | None | 0.999 | D | 0.678 | 0.563 | 0.713815690768 | gnomAD-4.0.0 | 6.5703E-06 | None | None | None | None | N | None | 2.41266E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/F | 35664 |
Ig-167 |
58 | rs781108499 |
0.5243 | -1.529 | 1.0 | N | 0.802 | 0.724 | 0.681819901562 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 1E-04 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/F | 35664 |
Ig-167 |
58 | rs781108499 |
0.5243 | -1.529 | 1.0 | N | 0.802 | 0.724 | 0.681819901562 | gnomAD-4.0.0 | 6.84571E-07 | None | None | None | None | N | None | 0 | 0 | None | 3.83259E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 35664 |
Ig-167 |
58 | rs1060500501 |
0.9605 | -3.224 | 1.0 | N | 0.856 | 0.79 | 0.917674651404 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| I/S | 35664 |
Ig-167 |
58 | rs1060500501 |
0.9605 | -3.224 | 1.0 | N | 0.856 | 0.79 | 0.917674651404 | gnomAD-4.0.0 | 6.84664E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99951E-07 | 0 | 0 |
| I/T | 35664 |
Ig-167 |
58 | None | 0.9627 | None | 1.0 | N | 0.812 | 0.724 | 0.81977039619 | gnomAD-4.0.0 | 6.84664E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65788E-05 |
| I/V | 35664 |
Ig-167 |
58 | rs781108499 |
0.1382 | -1.161 | 0.993 | N | 0.397 | 0.466 | 0.763021800361 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| I/V | 35664 |
Ig-167 |
58 | rs781108499 |
0.1382 | -1.161 | 0.993 | N | 0.397 | 0.466 | 0.763021800361 | gnomAD-4.0.0 | 1.71143E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.04236E-05 | None | 0 | 0 | 1.79977E-05 | 0 | 4.97315E-05 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.