Structural position:

  • Domain Type: Ig
  • Aligned Position: 144
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
V/A 70 Ig-1 65 None 0.4927 None 0.11 N 0.314 0.441 0.531389887418 gnomAD-4.0.0 1.20036E-06 None None None -0.843(TCAP) N None 0 0 None 0 0 None 0 0 1.31255E-06 0 0
V/M 70 Ig-1 65 rs772248060 0.5696 -1.227 1.0 D 0.755 0.647 0.717771820488 gnomAD-2.1.1 4.77E-05 None None None -1.404(TCAP) N None 6.15E-05 0 None 0 0 None 2.28639E-04 None 0 3.52E-05 0
V/M 70 Ig-1 65 rs772248060 0.5696 -1.227 1.0 D 0.755 0.647 0.717771820488 gnomAD-3.1.2 4.6E-05 None None None -1.404(TCAP) N None 2.41E-05 0 0 0 0 None 0 0 8.82E-05 0 0
V/M 70 Ig-1 65 rs772248060 0.5696 -1.227 1.0 D 0.755 0.647 0.717771820488 gnomAD-4.0.0 2.41631E-05 None None None -1.404(TCAP) N None 2.66909E-05 0 None 0 0 None 0 0 2.11862E-05 1.09789E-04 3.20072E-05
A/G 1005 Ig-3 63 None 0.7655 None 1.0 D 0.579 0.441 0.574230370252 gnomAD-4.0.0 6.84088E-07 None None None None N None 0 0 None 0 2.52003E-05 None 0 0 0 0 0
A/T 1005 Ig-3 63 None 0.7093 None 1.0 N 0.726 0.416 0.485634191555 gnomAD-4.0.0 3.18122E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8567E-06 0 3.02224E-05
A/V 1005 Ig-3 63 rs1357635150 0.8332 -0.745 1.0 N 0.641 0.437 0.560453403006 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 9.94E-05 0 None 0 None 0 0 0
A/V 1005 Ig-3 63 rs1357635150 0.8332 -0.745 1.0 N 0.641 0.437 0.560453403006 gnomAD-4.0.0 1.36818E-06 None None None None N None 0 0 None 3.82614E-05 0 None 0 0 8.99313E-07 0 0
T/A 1146 Ig-4 65 None 0.2117 None 0.51 N 0.518 0.306 0.233785782151 gnomAD-4.0.0 1.59077E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8568E-06 0 0
V/A 1354 Ig-5 64 None 0.7138 None 0.977 N 0.514 0.506 0.613554143916 gnomAD-4.0.0 1.59079E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
V/F 1354 Ig-5 64 None 0.9284 None 0.993 D 0.743 0.616 0.864902878786 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
V/I 1354 Ig-5 64 rs752889135 0.1262 -0.905 0.898 N 0.507 0.241 0.533904276971 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.84E-06 0
A/T 1520 Ig-6 64 rs1060500440 0.1481 -1.512 0.032 N 0.379 0.184 0.294918367191 gnomAD-2.1.1 3.99E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
A/T 1520 Ig-6 64 rs1060500440 0.1481 -1.512 0.032 N 0.379 0.184 0.294918367191 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 1520 Ig-6 64 rs1060500440 0.1481 -1.512 0.032 N 0.379 0.184 0.294918367191 gnomAD-4.0.0 9.91505E-06 None None None None N None 1.33508E-05 1.66722E-05 None 0 0 None 0 0 1.18652E-05 0 0
A/V 1520 Ig-6 64 None 0.2327 None 0.032 N 0.383 0.212 0.286848849266 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.93751E-06 0 0
T/A 1620 Ig-7 65 None 0.0837 None 0.001 N 0.222 0.104 0.159798565429 gnomAD-4.0.0 1.59077E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85665E-06 0 0
I/F 2236 Ig-11 63 rs1328042181 0.6083 -1.476 0.942 N 0.677 0.475 0.48763082235 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
I/F 2236 Ig-11 63 rs1328042181 0.6083 -1.476 0.942 N 0.677 0.475 0.48763082235 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/F 2236 Ig-11 63 rs1328042181 0.6083 -1.476 0.942 N 0.677 0.475 0.48763082235 gnomAD-4.0.0 6.57237E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4702E-05 0 0
I/S 2236 Ig-11 63 None 0.7155 None 0.942 N 0.679 0.604 0.887779923866 gnomAD-4.0.0 6.84131E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99339E-07 0 0
I/T 2236 Ig-11 63 rs1189735228 0.313 -2.704 0.822 N 0.651 0.513 0.720646288817 gnomAD-2.1.1 7.96E-06 None None None None N None 0 0 None 0 5.45E-05 None 3.27E-05 None 0 0 0
I/T 2236 Ig-11 63 rs1189735228 0.313 -2.704 0.822 N 0.651 0.513 0.720646288817 gnomAD-4.0.0 2.73652E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79868E-06 2.31868E-05 0
I/V 2236 Ig-11 63 rs1328042181 0.0817 None 0.006 N 0.235 0.142 0.302459207581 gnomAD-4.0.0 3.18224E-06 None None None None N None 0 0 None 0 2.77593E-05 None 0 0 0 1.43279E-05 0
V/A 2328 Ig-12 62 rs997288701 0.5634 None 0.977 N 0.523 0.484 0.67495869481 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/A 2328 Ig-12 62 rs997288701 0.5634 None 0.977 N 0.523 0.484 0.67495869481 gnomAD-4.0.0 6.57307E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47016E-05 0 0
V/I 2328 Ig-12 62 rs2091939887 0.0988 None 0.117 D 0.325 0.303 0.478828542108 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 2328 Ig-12 62 rs2091939887 0.0988 None 0.117 D 0.325 0.303 0.478828542108 gnomAD-4.0.0 1.85875E-06 None None None None N None 1.33476E-05 0 None 0 0 None 0 0 0 1.09791E-05 1.60036E-05
M/I 2417 Ig-13 62 rs765426928 0.5354 -0.206 0.039 N 0.327 0.223 0.391930172978 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
M/I 2417 Ig-13 62 rs765426928 0.5354 -0.206 0.039 N 0.327 0.223 0.391930172978 gnomAD-4.0.0 1.59057E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
M/T 2417 Ig-13 62 rs758233166 0.3005 -0.974 0.159 N 0.411 0.333 0.67336208464 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.84E-06 0
T/I 2507 Ig-14 63 rs1280887940 0.509 None 0.999 N 0.772 0.478 0.5632085275 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
M/T 2594 Ig-15 62 rs764016233 0.3525 -1.758 0.01 N 0.37 0.355 0.623315389809 gnomAD-2.1.1 7.99E-06 None None None None N None 0 5.81E-05 None 0 0 None 0 None 0 0 0
M/T 2594 Ig-15 62 rs764016233 0.3525 -1.758 0.01 N 0.37 0.355 0.623315389809 gnomAD-4.0.0 2.05273E-06 None None None None N None 0 4.47768E-05 None 0 0 None 0 0 8.99415E-07 0 0
M/V 2594 Ig-15 62 rs913684550 0.1446 None 0.028 N 0.19 0.226 0.497741790239 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
M/V 2594 Ig-15 62 rs913684550 0.1446 None 0.028 N 0.19 0.226 0.497741790239 gnomAD-4.0.0 3.09849E-06 None None None None N None 0 0 None 0 0 None 0 0 4.23773E-06 0 0
T/A 2681 Ig-16 61 rs1412458944 0.0701 -1.333 None N 0.301 0.058 0.104622674875 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
T/A 2681 Ig-16 61 rs1412458944 0.0701 -1.333 None N 0.301 0.058 0.104622674875 gnomAD-4.0.0 1.59064E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
T/N 2681 Ig-16 61 rs1298500274 0.5725 -1.77 0.331 D 0.643 0.295 0.355658859761 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
T/N 2681 Ig-16 61 rs1298500274 0.5725 -1.77 0.331 D 0.643 0.295 0.355658859761 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/N 2681 Ig-16 61 rs1298500274 0.5725 -1.77 0.331 D 0.643 0.295 0.355658859761 gnomAD-4.0.0 6.57272E-06 None None None None N None 2.41371E-05 0 None 0 0 None 0 0 0 0 0
C/G 2769 Ig-17 63 rs1313199971 0.6567 -1.053 0.98 D 0.642 0.671 0.849388039696 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
C/G 2769 Ig-17 63 rs1313199971 0.6567 -1.053 0.98 D 0.642 0.671 0.849388039696 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
C/G 2769 Ig-17 63 rs1313199971 0.6567 -1.053 0.98 D 0.642 0.671 0.849388039696 gnomAD-4.0.0 3.71733E-06 None None None None N None 0 0 None 0 0 None 0 0 5.08465E-06 0 0
C/R 2769 Ig-17 63 None 0.9884 None 0.997 D 0.711 0.685 0.848577320525 gnomAD-4.0.0 6.84068E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99292E-07 0 0
I/V 2856 Ig-18 62 rs1387078141 0.092 -1.867 0.002 N 0.162 0.159 0.42748209135 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
I/V 2856 Ig-18 62 rs1387078141 0.092 -1.867 0.002 N 0.162 0.159 0.42748209135 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 2856 Ig-18 62 rs1387078141 0.092 -1.867 0.002 N 0.162 0.159 0.42748209135 gnomAD-4.0.0 5.12232E-06 None None None None N None 0 0 None 0 0 None 0 0 9.56672E-06 0 0
T/I 2943 Ig-19 62 rs1316613829 0.474 None 1.0 N 0.792 0.537 0.55355060856 gnomAD-4.0.0 1.5905E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
V/I 3030 Ig-20 62 rs895908518 0.2331 -0.906 0.997 D 0.518 0.388 0.767850428655 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.8E-06 0
V/I 3030 Ig-20 62 rs895908518 0.2331 -0.906 0.997 D 0.518 0.388 0.767850428655 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 3030 Ig-20 62 rs895908518 0.2331 -0.906 0.997 D 0.518 0.388 0.767850428655 gnomAD-4.0.0 2.47831E-06 None None None None N None 0 0 None 0 0 None 0 0 3.38977E-06 0 0
T/A 3119 Ig-21 62 None 0.1134 None 0.003 N 0.225 0.164 0.124217242631 gnomAD-4.0.0 6.84078E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15931E-05 0
T/I 3119 Ig-21 62 rs1444407818 0.455 -0.346 0.309 N 0.516 0.227 0.273503213844 gnomAD-2.1.1 7.08E-06 None None None None N None 0 2.82E-05 None 0 0 None 0 None 0 7.76E-06 0
T/I 3119 Ig-21 62 rs1444407818 0.455 -0.346 0.309 N 0.516 0.227 0.273503213844 gnomAD-4.0.0 1.59054E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85651E-06 0 0
T/S 3119 Ig-21 62 rs775164752 0.3983 -1.723 0.028 N 0.264 0.16 0.158396225186 gnomAD-2.1.1 7.97E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.76E-05 0
T/S 3119 Ig-21 62 rs775164752 0.3983 -1.723 0.028 N 0.264 0.16 0.158396225186 gnomAD-4.0.0 4.78854E-06 None None None None N None 0 0 None 0 0 None 0 0 6.29507E-06 0 0
A/D 3301 Ig-23 63 rs776187090 0.9782 -2.863 0.549 D 0.593 0.517 0.530803083455 gnomAD-2.1.1 7.97E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.76E-05 0
A/D 3301 Ig-23 63 rs776187090 0.9782 -2.863 0.549 D 0.593 0.517 0.530803083455 gnomAD-4.0.0 2.73632E-06 None None None None N None 0 0 None 0 0 None 0 1.73732E-04 2.6979E-06 0 0
A/T 3301 Ig-23 63 rs1317267651 0.1444 -1.903 0.007 N 0.158 0.297 0.241664281697 gnomAD-2.1.1 7.97E-06 None None None None N None 0 0 None 0 0 None 6.53E-05 None 0 0 0
A/T 3301 Ig-23 63 rs1317267651 0.1444 -1.903 0.007 N 0.158 0.297 0.241664281697 gnomAD-4.0.0 3.18107E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86549E-05 0
A/V 3301 Ig-23 63 None 0.258 None 0.007 N 0.186 0.283 0.252162846088 gnomAD-4.0.0 6.8408E-07 None None None None N None 0 0 None 0 0 None 0 0 8.993E-07 0 0
A/V 3529 Ig-25 65 None 0.3725 None None None None 0.269 None gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/A 3882 Ig-27 63 rs2082491063 0.1071 None None N 0.088 0.093 None gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/A 3882 Ig-27 63 rs2082491063 0.1071 None None N 0.088 0.093 None gnomAD-4.0.0 6.57333E-06 None None None None I None 2.41383E-05 0 None 0 0 None 0 0 0 0 0
P/R 4001 Ig-28 64 rs1292211761 0.911 -1.309 0.863 N 0.669 0.254 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/R 4001 Ig-28 64 rs1292211761 0.911 -1.309 0.863 N 0.669 0.254 None gnomAD-4.0.0 4.77625E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.29812E-05 0
P/T 4001 Ig-28 64 rs1320141997 0.413 -2.336 0.27 N 0.485 0.16 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/T 4001 Ig-28 64 rs1320141997 0.413 -2.336 0.27 N 0.485 0.16 None gnomAD-4.0.0 1.592E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
V/I 4666 Ig-29 61 rs1361124171 0.1032 -1.021 0.565 D 0.545 0.19 None gnomAD-2.1.1 4.24E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.3E-06 0
V/I 4666 Ig-29 61 rs1361124171 0.1032 -1.021 0.565 D 0.545 0.19 None gnomAD-4.0.0 1.04332E-05 None None None None N None 0 2.292E-05 None 0 0 None 0 0 1.1851E-05 0 1.68674E-05
V/L 4666 Ig-29 61 None 0.4107 None 0.349 D 0.549 0.209 None gnomAD-4.0.0 1.3911E-06 None None None None N None 0 0 None 0 0 None 0 0 1.82322E-06 0 0
T/I 4762 Ig-30 63 rs2081863914 0.7429 None 0.934 N 0.55 0.346 0.453679287548 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/P 4762 Ig-30 63 rs1439059332 0.261 None 0.002 N 0.248 0.349 0.28297238246 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/P 4762 Ig-30 63 rs1439059332 0.261 None 0.002 N 0.248 0.349 0.28297238246 gnomAD-4.0.0 1.85937E-06 None None None None I None 0 0 None 0 0 None 0 0 2.54289E-06 0 0
L/F 4857 Ig-31 63 None 0.5299 None 0.999 N 0.782 0.368 0.707450365078 gnomAD-4.0.0 2.05257E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69833E-06 0 0
L/I 4857 Ig-31 63 None 0.1159 None 0.992 N 0.562 0.269 0.555908562551 gnomAD-4.0.0 1.36838E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79889E-06 0 0
L/R 4857 Ig-31 63 rs1267218460 0.787 -1.496 1.0 N 0.782 0.744 0.858254026184 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
L/R 4857 Ig-31 63 rs1267218460 0.787 -1.496 1.0 N 0.782 0.744 0.858254026184 gnomAD-4.0.0 3.18227E-06 None None None None N None 0 0 None 0 0 None 0 2.41313E-04 2.85794E-06 0 0
V/L 5044 Ig-33 64 None 0.3071 None 0.002 N 0.146 0.236 0.418964662724 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
F/L 5137 Ig-34 63 rs1417172594 0.9116 -1.89 0.999 N 0.5 0.437 0.376921832658 gnomAD-2.1.1 8.05E-06 None None None None N None 1.29216E-04 0 None 0 0 None 0 None 0 0 0
F/L 5137 Ig-34 63 rs1417172594 0.9116 -1.89 0.999 N 0.5 0.437 0.376921832658 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
F/L 5137 Ig-34 63 rs1417172594 0.9116 -1.89 0.999 N 0.5 0.437 0.376921832658 gnomAD-4.0.0 2.56245E-06 None None None None N None 3.38318E-05 0 None 0 0 None 0 0 0 0 0
V/I 5230 Ig-35 63 rs369294144 0.0797 -0.849 0.117 N 0.337 0.157 None gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
V/I 5230 Ig-35 63 rs369294144 0.0797 -0.849 0.117 N 0.337 0.157 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 5230 Ig-35 63 rs369294144 0.0797 -0.849 0.117 N 0.337 0.157 None gnomAD-4.0.0 2.47869E-06 None None None None N None 2.66944E-05 0 None 0 0 None 0 0 0 0 3.20246E-05
A/G 5323 Ig-36 63 None 0.473 None 0.046 D 0.295 0.458 0.462461958149 gnomAD-4.0.0 1.59137E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85832E-06 0 0
A/T 5323 Ig-36 63 rs745667963 0.1736 -1.293 0.322 N 0.353 0.227 None gnomAD-2.1.1 8.05E-06 None None None None N None 1.29199E-04 0 None 0 0 None 0 None 0 0 0
A/T 5323 Ig-36 63 rs745667963 0.1736 -1.293 0.322 N 0.353 0.227 None gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
A/T 5323 Ig-36 63 rs745667963 0.1736 -1.293 0.322 N 0.353 0.227 None gnomAD-4.0.0 3.84332E-06 None None None None N None 5.0734E-05 0 None 0 0 None 0 0 0 0 0
V/A 5419 Ig-37 63 rs1352050140 0.1606 -2.386 0.334 N 0.501 0.302 0.587751488883 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/A 5419 Ig-37 63 rs1352050140 0.1606 -2.386 0.334 N 0.501 0.302 0.587751488883 gnomAD-4.0.0 1.59198E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85873E-06 0 0
V/I 5419 Ig-37 63 None 0.0905 None 0.004 N 0.243 0.126 0.452928561435 gnomAD-4.0.0 2.053E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79902E-06 1.15945E-05 0
V/I 5512 Ig-38 63 None 0.1176 None 0.962 N 0.497 0.364 0.645824608598 gnomAD-4.0.0 1.59154E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
V/A 5606 Ig-39 64 rs1356962832 0.1049 -1.875 0.027 N 0.427 0.23 0.393316636838 gnomAD-4.0.0 2.73687E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59795E-06 0 0
V/F 5606 Ig-39 64 None 0.2364 None 0.317 D 0.624 0.212 0.557519804684 gnomAD-4.0.0 1.59131E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85843E-06 0 0
F/S 5699 Ig-40 63 rs929174376 0.6895 None 0.997 N 0.646 0.545 0.883764784581 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
F/S 5699 Ig-40 63 rs929174376 0.6895 None 0.997 N 0.646 0.545 0.883764784581 gnomAD-4.0.0 6.57419E-06 None None None None N None 0 6.55222E-05 None 0 0 None 0 0 0 0 0
I/M 5792 Ig-41 63 rs1041967765 0.1373 -1.341 0.966 N 0.568 0.366 0.158396225186 gnomAD-2.1.1 8.04E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 8.88E-06 0
I/M 5792 Ig-41 63 rs1041967765 0.1373 -1.341 0.966 N 0.568 0.366 0.158396225186 gnomAD-4.0.0 6.36478E-06 None None None None N None 0 4.57289E-05 None 0 0 None 0 0 5.71644E-06 0 0
I/T 5792 Ig-41 63 rs1225094303 0.2581 -2.196 0.051 N 0.331 0.344 0.181679512989 gnomAD-2.1.1 8.04E-06 None None None None N None 0 5.79E-05 None 0 0 None 0 None 0 0 0
I/T 5792 Ig-41 63 rs1225094303 0.2581 -2.196 0.051 N 0.331 0.344 0.181679512989 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
I/T 5792 Ig-41 63 rs1225094303 0.2581 -2.196 0.051 N 0.331 0.344 0.181679512989 gnomAD-4.0.0 6.40544E-06 None None None None N None 0 5.08457E-05 None 0 0 None 0 0 4.78586E-06 0 0
A/T 6074 Ig-44 63 None 0.0932 None 0.031 N 0.397 0.171 0.326881540566 gnomAD-4.0.0 1.36873E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7991E-06 0 0
A/T 6168 Ig-45 64 rs764768881 0.0978 -1.37 0.006 N 0.255 0.191 0.280181792013 gnomAD-2.1.1 1.79E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.91E-05 0
A/T 6168 Ig-45 64 rs764768881 0.0978 -1.37 0.006 N 0.255 0.191 0.280181792013 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 6168 Ig-45 64 rs764768881 0.0978 -1.37 0.006 N 0.255 0.191 0.280181792013 gnomAD-4.0.0 2.16901E-05 None None None None N None 1.33504E-05 0 None 0 0 None 0 0 2.88197E-05 0 0
C/R 6261 Ig-46 63 rs1438614038 0.9237 None 1.0 N 0.783 0.657 0.853965696696 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
C/R 6261 Ig-46 63 rs1438614038 0.9237 None 1.0 N 0.783 0.657 0.853965696696 gnomAD-4.0.0 3.84435E-06 None None None None N None 3.38421E-05 0 None 0 0 None 0 0 0 0 2.84511E-05
C/Y 6261 Ig-46 63 rs1060500581 0.6594 -1.305 1.0 N 0.772 0.44 0.799932464155 gnomAD-2.1.1 8.07E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
C/Y 6261 Ig-46 63 rs1060500581 0.6594 -1.305 1.0 N 0.772 0.44 0.799932464155 gnomAD-4.0.0 4.77515E-06 None None None None N None 0 4.57457E-05 None 0 0 None 0 0 2.85925E-06 0 0
V/M 6354 Ig-47 63 rs754383943 0.3432 -1.602 0.998 D 0.564 0.495 0.668719517119 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/M 6354 Ig-47 63 rs754383943 0.3432 -1.602 0.998 D 0.564 0.495 0.668719517119 gnomAD-4.0.0 6.57358E-06 None None None None N None 2.41348E-05 0 None 0 0 None 0 0 0 0 0
V/A 6447 Ig-48 63 rs1270776568 0.2677 None 0.116 N 0.162 0.22 0.52127940124 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/A 6447 Ig-48 63 rs1270776568 0.2677 None 0.116 N 0.162 0.22 0.52127940124 gnomAD-4.0.0 1.31482E-05 None None None None N None 4.82789E-05 0 None 0 0 None 0 0 0 0 0
L/M 6543 Ig-49 63 rs1578117153 0.2644 -2.103 1.0 D 0.771 0.409 0.624477516964 gnomAD-4.0.0 1.59379E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02902E-05
V/A 6636 Ig-50 63 rs1258812731 0.3178 -2.191 1.0 D 0.531 0.499 0.729420930906 gnomAD-2.1.1 1.61E-05 None None None None N None 0 1.1605E-04 None 0 0 None 0 None 0 0 0
V/A 6636 Ig-50 63 rs1258812731 0.3178 -2.191 1.0 D 0.531 0.499 0.729420930906 gnomAD-4.0.0 4.77824E-06 None None None None N None 0 6.86091E-05 None 0 0 None 0 0 0 0 0
V/E 6823 Ig-52 63 None 0.9109 None 0.991 D 0.601 0.601 0.791347535812 gnomAD-4.0.0 6.8443E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.16001E-05 0
V/G 6823 Ig-52 63 rs529417675 0.5924 -2.075 0.967 D 0.63 0.572 0.789912218454 gnomAD-2.1.1 2.01E-05 None None None None N None 0 0 None 0 0 None 1.63527E-04 None 0 0 0
V/G 6823 Ig-52 63 rs529417675 0.5924 -2.075 0.967 D 0.63 0.572 0.789912218454 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06954E-04 0
V/G 6823 Ig-52 63 rs529417675 0.5924 -2.075 0.967 D 0.63 0.572 0.789912218454 1000 genomes 3.99361E-04 None None None None N None 0 0 None None 0 0 None None None 2E-03 None
V/G 6823 Ig-52 63 rs529417675 0.5924 -2.075 0.967 D 0.63 0.572 0.789912218454 gnomAD-4.0.0 1.17767E-05 None None None None N None 0 0 None 0 0 None 0 0 3.39126E-06 1.53789E-04 1.60133E-05
V/M 6823 Ig-52 63 None 0.2195 None 0.88 D 0.585 0.429 0.54173910141 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 7010 Ig-54 63 rs2078969051 0.1066 None None N 0.157 0.167 0.412064437402 gnomAD-4.0.0 1.59182E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43295E-05 0
V/F 7010 Ig-54 63 None 0.6612 None 0.175 N 0.652 0.278 0.540518506614 gnomAD-4.0.0 6.84316E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99582E-07 0 0
V/I 7010 Ig-54 63 rs564660466 0.1263 -0.989 0.001 N 0.243 0.065 0.183819452728 gnomAD-2.1.1 4.42E-05 None None None None N None 0 0 None 0 4.45881E-04 None 0 None 0 2.66E-05 0
V/I 7010 Ig-54 63 rs564660466 0.1263 -0.989 0.001 N 0.243 0.065 0.183819452728 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 1.92901E-04 None 9.41E-05 0 0 0 0
V/I 7010 Ig-54 63 rs564660466 0.1263 -0.989 0.001 N 0.243 0.065 0.183819452728 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
V/I 7010 Ig-54 63 rs564660466 0.1263 -0.989 0.001 N 0.243 0.065 0.183819452728 gnomAD-4.0.0 1.23948E-05 None None None None N None 0 0 None 0 2.22946E-04 None 1.56201E-05 0 7.6296E-06 0 0
I/S 7199 Ig-56 63 rs781566455 0.1827 None 0.012 N 0.545 0.242 0.633806126401 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/S 7199 Ig-56 63 rs781566455 0.1827 None 0.012 N 0.545 0.242 0.633806126401 gnomAD-4.0.0 6.57194E-06 None None None None N None 2.41278E-05 0 None 0 0 None 0 0 0 0 0
I/T 7199 Ig-56 63 rs781566455 0.0568 -2.523 None N 0.447 0.214 0.572208630285 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.67E-05 0
I/T 7199 Ig-56 63 rs781566455 0.0568 -2.523 None N 0.447 0.214 0.572208630285 gnomAD-3.1.2 1.97E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
I/T 7199 Ig-56 63 rs781566455 0.0568 -2.523 None N 0.447 0.214 0.572208630285 gnomAD-4.0.0 4.95888E-06 None None None None N None 4.00523E-05 0 None 0 0 None 0 0 4.23865E-06 0 0
S/N 7292 Ig-57 63 None 0.3244 None 0.959 N 0.504 0.351 0.360961692134 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/L 7385 Ig-58 63 rs1273152724 0.4196 -0.783 0.944 N 0.493 0.317 0.540153309661 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/L 7385 Ig-58 63 rs1273152724 0.4196 -0.783 0.944 N 0.493 0.317 0.540153309661 gnomAD-4.0.0 1.59266E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4339E-05 0
T/I 7481 Ig-59 63 None 0.5067 None 0.898 N 0.507 0.288 0.413113201963 gnomAD-4.0.0 6.84444E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9968E-07 0 0
T/N 7481 Ig-59 63 None 0.5278 None 0.962 N 0.573 0.392 0.481616744073 gnomAD-4.0.0 1.36889E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79936E-06 0 0
A/G 7671 Ig-61 64 rs1230535310 0.2615 -1.278 0.201 D 0.471 0.405 0.336892272479 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
A/G 7671 Ig-61 64 rs1230535310 0.2615 -1.278 0.201 D 0.471 0.405 0.336892272479 gnomAD-4.0.0 9.55578E-06 None None None None N None 0 0 None 0 1.66417E-04 None 0 0 0 0 0
A/T 7671 Ig-61 64 rs1560675339 0.1286 None 0.007 N 0.172 0.213 0.203808441222 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 7671 Ig-61 64 rs1560675339 0.1286 None 0.007 N 0.172 0.213 0.203808441222 gnomAD-4.0.0 6.57151E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47033E-05 0 0
L/I 7764 Ig-62 63 None 0.1096 None 0.027 N 0.485 0.049 0.256283259241 gnomAD-4.0.0 1.59156E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43295E-05 0
L/P 7764 Ig-62 63 rs1413753534 0.8771 -2.22 0.741 N 0.654 0.42 0.824210825843 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
L/P 7764 Ig-62 63 rs1413753534 0.8771 -2.22 0.741 N 0.654 0.42 0.824210825843 gnomAD-4.0.0 1.36852E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99538E-07 0 1.65678E-05
A/T 7951 Ig-64 63 None 0.1215 None 0.001 N 0.3 0.133 0.247872288689 gnomAD-4.0.0 2.05267E-06 None None None None N None 2.98811E-05 0 None 0 0 None 0 0 1.799E-06 0 0
V/M 8140 Ig-66 63 rs377210838 0.3199 -1.18 0.978 D 0.753 0.615 None gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
V/M 8140 Ig-66 63 rs377210838 0.3199 -1.18 0.978 D 0.753 0.615 None gnomAD-4.0.0 1.36843E-06 None None None None N None 0 0 None 0 0 None 0 0 8.9948E-07 0 1.65656E-05
S/N 8233 Ig-67 63 None 0.4238 None 0.051 N 0.247 0.289 0.242825505644 gnomAD-4.0.0 6.84224E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99489E-07 0 0
V/L 8518 Ig-70 63 None 0.4798 None 0.005 N 0.41 0.156 0.334659703779 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/F 8612 Ig-71 64 rs755695660 0.446 -1.757 0.97 N 0.605 0.2 0.592743537544 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
L/F 8612 Ig-71 64 rs755695660 0.446 -1.757 0.97 N 0.605 0.2 0.592743537544 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
L/F 8612 Ig-71 64 rs755695660 0.446 -1.757 0.97 N 0.605 0.2 0.592743537544 gnomAD-4.0.0 1.85944E-06 None None None None N None 0 3.33478E-05 None 0 0 None 0 0 8.47725E-07 0 0
L/R 8612 Ig-71 64 rs1345942434 0.7792 None 0.999 N 0.618 0.5 0.829248476454 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
L/R 8612 Ig-71 64 rs1345942434 0.7792 None 0.999 N 0.618 0.5 0.829248476454 gnomAD-4.0.0 6.58155E-06 None None None None N None 2.41674E-05 0 None 0 0 None 0 0 0 0 0
V/M 8799 Ig-73 64 rs1560601919 0.1693 None 0.295 N 0.537 0.214 0.389283895039 gnomAD-4.0.0 6.15807E-06 None None None None N None 0 0 None 0 0 None 0 0 8.09545E-06 0 0
V/I 8892 Ig-74 63 rs747832107 0.1169 -0.491 0.042 D 0.447 0.119 0.342631996419 gnomAD-2.1.1 6.43E-05 None None None None N None 0 5.10204E-04 None 0 0 None 0 None 0 0 0
V/I 8892 Ig-74 63 rs747832107 0.1169 -0.491 0.042 D 0.447 0.119 0.342631996419 gnomAD-3.1.2 8.54E-05 None None None None N None 0 8.51566E-04 0 0 0 None 0 0 0 0 0
V/I 8892 Ig-74 63 rs747832107 0.1169 -0.491 0.042 D 0.447 0.119 0.342631996419 gnomAD-4.0.0 3.844E-05 None None None None N None 0 4.74737E-04 None 0 0 None 0 0 0 1.34052E-05 2.84544E-05
L/M 8988 Ig-75 63 rs2076915849 0.2632 None 0.971 D 0.573 0.284 0.583928190899 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/M 8988 Ig-75 63 rs2076915849 0.2632 None 0.971 D 0.573 0.284 0.583928190899 gnomAD-4.0.0 6.57471E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4702E-05 0 0
L/P 8988 Ig-75 63 rs2076915544 0.7108 None 0.032 N 0.486 0.447 0.714032942311 gnomAD-4.0.0 3.18277E-06 None None None None N None 0 0 None 0 5.54754E-05 None 0 0 0 0 0
S/N 9174 Ig-77 63 None 0.3011 None None N 0.209 0.197 0.207176502487 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 9267 Ig-78 63 rs755143548 0.2321 -1.575 0.116 N 0.173 0.242 0.359763055319 gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
V/A 9267 Ig-78 63 rs755143548 0.2321 -1.575 0.116 N 0.173 0.242 0.359763055319 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
V/A 9267 Ig-78 63 rs755143548 0.2321 -1.575 0.116 N 0.173 0.242 0.359763055319 gnomAD-4.0.0 1.48724E-05 None None None None N None 0 1.66694E-05 None 0 0 None 0 0 1.94952E-05 0 0
V/G 9267 Ig-78 63 None 0.5773 None 0.959 D 0.543 0.741 0.898619077821 gnomAD-4.0.0 6.8422E-07 None None None None N None 0 2.23634E-05 None 0 0 None 0 0 0 0 0
V/I 9267 Ig-78 63 rs1476692496 0.1421 None 0.906 D 0.511 0.269 0.439763647824 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 9267 Ig-78 63 rs1476692496 0.1421 None 0.906 D 0.511 0.269 0.439763647824 gnomAD-4.0.0 6.57186E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46968E-05 0 0
T/I 9363 Ig-79 63 rs1430247866 0.6563 None 0.988 None 0.6 0.303 0.463672176093 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
T/I 9363 Ig-79 63 rs1430247866 0.6563 None 0.988 None 0.6 0.303 0.463672176093 gnomAD-4.0.0 6.57168E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07039E-04 0
T/N 9363 Ig-79 63 rs1430247866 0.5393 -2.03 0.959 None 0.551 0.443 0.550503487074 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 6.41026E-04 None 0 None 0 0 0
T/N 9363 Ig-79 63 rs1430247866 0.5393 -2.03 0.959 None 0.551 0.443 0.550503487074 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92308E-04 None 0 0 0 0 0
T/N 9363 Ig-79 63 rs1430247866 0.5393 -2.03 0.959 None 0.551 0.443 0.550503487074 gnomAD-4.0.0 6.57168E-06 None None None None N None 0 0 None 0 1.92308E-04 None 0 0 0 0 0
V/A 9459 Ig-80 63 rs541910545 0.166 -2.297 0.005 None 0.164 0.186 0.450343601259 gnomAD-2.1.1 8.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 3.27E-05 None 0 0 0
V/A 9459 Ig-80 63 rs541910545 0.166 -2.297 0.005 None 0.164 0.186 0.450343601259 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/A 9459 Ig-80 63 rs541910545 0.166 -2.297 0.005 None 0.164 0.186 0.450343601259 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
V/A 9459 Ig-80 63 rs541910545 0.166 -2.297 0.005 None 0.164 0.186 0.450343601259 gnomAD-4.0.0 2.47867E-06 None None None None N None 2.6656E-05 1.66644E-05 None 0 0 None 0 0 0 1.09798E-05 0
A/G 9556 Ig-81 64 rs1060500482 0.2904 -1.461 0.669 None 0.482 0.402 0.350746614512 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
A/G 9556 Ig-81 64 rs1060500482 0.2904 -1.461 0.669 None 0.482 0.402 0.350746614512 gnomAD-4.0.0 6.84186E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99457E-07 0 0
A/T 9556 Ig-81 64 rs1381808931 0.2215 -1.512 0.669 None 0.485 0.221 0.268660756437 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.85E-06 0
A/T 9556 Ig-81 64 rs1381808931 0.2215 -1.512 0.669 None 0.485 0.221 0.268660756437 gnomAD-4.0.0 1.36836E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7989E-06 0 0
A/V 9556 Ig-81 64 rs1060500482 0.2694 -0.562 0.012 None 0.327 0.199 0.321672782286 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/V 9556 Ig-81 64 rs1060500482 0.2694 -0.562 0.012 None 0.327 0.199 0.321672782286 gnomAD-4.0.0 5.47349E-06 None None None None N None 0 0 None 0 0 None 0 0 6.2962E-06 1.15934E-05 0
V/M 9652 Ig-82 63 None 0.3392 None 0.317 None 0.549 0.252 0.468168183122 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/A 9761 Ig-83 64 rs757275707 0.1901 0.12 0.022 None 0.172 0.134 0.186928172975 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
T/A 9761 Ig-83 64 rs757275707 0.1901 0.12 0.022 None 0.172 0.134 0.186928172975 gnomAD-4.0.0 1.59097E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
T/S 9761 Ig-83 64 rs753921516 0.6346 -1.106 0.051 None 0.213 0.192 0.247872288689 gnomAD-2.1.1 8.02E-06 None None None None N None 0 0 None 0 5.56E-05 None 3.27E-05 None 0 0 0
T/S 9761 Ig-83 64 rs753921516 0.6346 -1.106 0.051 None 0.213 0.192 0.247872288689 gnomAD-4.0.0 3.18199E-06 None None None None N None 0 0 None 0 2.77285E-05 None 0 0 0 1.43279E-05 0
C/G 9963 Ig-84 64 rs771005008 0.9076 -0.607 0.994 None 0.699 0.662 0.883891755503 gnomAD-2.1.1 2.42E-05 None None None None N None 0 0 None 0 0 None 1.97252E-04 None 0 0 0
C/G 9963 Ig-84 64 rs771005008 0.9076 -0.607 0.994 None 0.699 0.662 0.883891755503 gnomAD-4.0.0 1.30036E-05 None None None None N None 0 0 None 0 0 None 0 0 0 2.20612E-04 0
A/T 13842 Ig-88 63 None 0.1518 None 0.002 N 0.184 0.098 0.0806252709748 gnomAD-4.0.0 6.8441E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99667E-07 0 0
A/V 13842 Ig-88 63 rs1231962760 0.245 -0.315 0.379 N 0.643 0.268 0.185906805712 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 9.96E-05 0 None 0 None 0 0 0
A/V 13842 Ig-88 63 rs1231962760 0.245 -0.315 0.379 N 0.643 0.268 0.185906805712 gnomAD-4.0.0 1.5924E-06 None None None None N None 0 0 None 4.76917E-05 0 None 0 0 0 0 0
A/D 13937 Ig-89 62 None 0.9927 None 0.963 N 0.771 0.256 0.566919426312 gnomAD-4.0.0 6.90088E-07 None None None None N None 0 2.33242E-05 None 0 0 None 0 0 0 0 0
A/V 13937 Ig-89 62 rs545806408 0.2796 -0.426 0.016 N 0.418 0.072 0.327686398923 gnomAD-2.1.1 4.2682E-04 None None None None N None 0 0 None 0 0 None 3.32773E-03 None 0 1.99E-05 0
A/V 13937 Ig-89 62 rs545806408 0.2796 -0.426 0.016 N 0.418 0.072 0.327686398923 gnomAD-3.1.2 1.31581E-04 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 3.94518E-03 0
A/V 13937 Ig-89 62 rs545806408 0.2796 -0.426 0.016 N 0.418 0.072 0.327686398923 1000 genomes 1.39776E-03 None None None None N None 0 0 None None 0 0 None None None 7.2E-03 None
A/V 13937 Ig-89 62 rs545806408 0.2796 -0.426 0.016 N 0.418 0.072 0.327686398923 gnomAD-4.0.0 1.69248E-04 None None None None N None 1.33504E-05 0 None 0 0 None 0 0 5.11537E-06 2.77175E-03 2.58006E-04
V/L 14026 Ig-90 62 None 0.8906 None 0.994 N 0.607 0.34 0.432493127443 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/M 14203 Ig-92 62 rs761861743 0.5812 -1.278 0.638 D 0.591 0.456 0.693830937314 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/M 14203 Ig-92 62 rs761861743 0.5812 -1.278 0.638 D 0.591 0.456 0.693830937314 gnomAD-4.0.0 1.592E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
A/V 14291 Ig-93 61 rs746486506 0.166 -0.677 0.004 N 0.183 0.141 0.288727942641 gnomAD-2.1.1 1.21E-05 None None None None N None 0 5.8E-05 None 0 0 None 3.27E-05 None 0 0 0
A/V 14291 Ig-93 61 rs746486506 0.166 -0.677 0.004 N 0.183 0.141 0.288727942641 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
A/V 14291 Ig-93 61 rs746486506 0.166 -0.677 0.004 N 0.183 0.141 0.288727942641 gnomAD-4.0.0 5.57948E-06 None None None None N None 1.33626E-05 3.33667E-05 None 0 0 None 0 0 2.54328E-06 3.29439E-05 0
C/R 14380 Ig-94 62 rs557125278 0.978 -0.965 0.999 N 0.849 0.619 0.680717446325 gnomAD-2.1.1 3.75811E-04 None None None None N None 0 0 None 0 0 None 3.30303E-03 None 0 7.84E-06 4.22654E-04
C/R 14380 Ig-94 62 rs557125278 0.978 -0.965 0.999 N 0.849 0.619 0.680717446325 gnomAD-3.1.2 1.44615E-04 None None None None N None 0 0 0 0 1.93648E-04 None 0 0 1.47E-05 4.13736E-03 0
C/R 14380 Ig-94 62 rs557125278 0.978 -0.965 0.999 N 0.849 0.619 0.680717446325 1000 genomes 1.59744E-03 None None None None N None 0 0 None None 0 0 None None None 8.2E-03 None
C/R 14380 Ig-94 62 rs557125278 0.978 -0.965 0.999 N 0.849 0.619 0.680717446325 gnomAD-4.0.0 2.07655E-04 None None None None N None 0 0 None 0 2.23454E-05 None 0 3.30579E-04 1.35657E-05 3.31657E-03 2.24179E-04
A/G 14469 Ig-95 62 None 0.4154 None 0.911 D 0.574 0.549 0.405422107966 gnomAD-4.0.0 1.59203E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85969E-06 0 0
A/T 14647 Ig-97 62 None 0.1834 None 0.009 N 0.375 0.115 0.249502417897 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 6.17284E-04 0 0 0
A/V 14647 Ig-97 62 rs1647945461 0.2011 None 0.009 N 0.377 0.227 0.249502417897 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/V 14647 Ig-97 62 rs1647945461 0.2011 None 0.009 N 0.377 0.227 0.249502417897 gnomAD-4.0.0 6.57765E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47076E-05 0 0
C/S 14736 Ig-98 62 None 0.7828 None 0.791 N 0.646 0.237 0.41859458845 gnomAD-4.0.0 1.59311E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86103E-06 0 0
V/A 14825 Ig-99 61 rs1213950767 0.6101 -1.413 0.094 N 0.493 0.251 0.482574385019 gnomAD-2.1.1 8.38E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.83E-05 0
V/A 14825 Ig-99 61 rs1213950767 0.6101 -1.413 0.094 N 0.493 0.251 0.482574385019 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78927E-04
V/A 14825 Ig-99 61 rs1213950767 0.6101 -1.413 0.094 N 0.493 0.251 0.482574385019 gnomAD-4.0.0 8.114E-06 None None None None N None 0 0 None 0 0 None 0 0 1.02125E-05 0 1.61358E-05
C/Y 14914 Ig-100 62 rs773211286 0.97 -1.242 0.89 D 0.697 0.488 0.798853050747 gnomAD-2.1.1 2.82E-05 None None None None N None 0 0 None 0 3.367E-04 None 0 None 0 8.92E-06 0
C/Y 14914 Ig-100 62 rs773211286 0.97 -1.242 0.89 D 0.697 0.488 0.798853050747 gnomAD-4.0.0 2.66997E-05 None None None None N None 0 0 None 0 9.35099E-04 None 0 0 1.79973E-06 0 0
A/S 15092 Ig-102 62 None 0.1708 None 0.549 D 0.553 0.308 0.497679007273 gnomAD-4.0.0 6.8469E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99931E-07 0 0
A/T 15092 Ig-102 62 rs760392307 0.1514 -1.654 0.729 N 0.561 0.283 None gnomAD-2.1.1 3.63E-05 None None None None N None 0 5.82E-05 None 0 0 None 3.27E-05 None 4.64E-05 3.57E-05 1.66445E-04
A/T 15092 Ig-102 62 rs760392307 0.1514 -1.654 0.729 N 0.561 0.283 None gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 2.88184E-04 0 None 0 0 4.42E-05 0 0
A/T 15092 Ig-102 62 rs760392307 0.1514 -1.654 0.729 N 0.561 0.283 None gnomAD-4.0.0 1.61254E-05 None None None None N None 0 1.67196E-05 None 3.38295E-05 0 None 1.56245E-05 0 1.52659E-05 1.09815E-05 6.41169E-05
A/V 15092 Ig-102 62 None 0.2105 None 0.001 N 0.249 0.147 0.408036853922 gnomAD-4.0.0 1.59387E-06 None None None None N None 0 0 None 0 2.78412E-05 None 0 0 0 0 0
A/P 15269 Ig-104 62 None 0.7388 None 0.949 D 0.687 0.546 0.605722390383 gnomAD-4.0.0 1.59334E-06 None None None None N None 0 0 None 0 2.77685E-05 None 0 0 0 0 0
A/V 15269 Ig-104 62 rs1576550520 0.1744 None 0.075 N 0.375 0.231 0.435152311215 gnomAD-4.0.0 1.59332E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86266E-06 0 0
C/G 15363 Ig-105 62 None 0.6198 None 0.698 D 0.695 0.467 0.831465730767 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
C/G 15452 Ig-106 62 rs2058039119 0.8765 None 1.0 D 0.759 0.625 0.888152567264 gnomAD-4.0.0 1.36991E-06 None None None None N None 5.99233E-05 0 None 0 0 None 0 0 0 0 0
C/R 15452 Ig-106 62 None 0.995 None 1.0 D 0.809 0.734 0.892143059017 gnomAD-4.0.0 6.84955E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.6592E-05
C/S 15452 Ig-106 62 rs2058039119 0.9007 None 1.0 N 0.727 0.587 0.755270211524 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
C/S 15452 Ig-106 62 rs2058039119 0.9007 None 1.0 N 0.727 0.587 0.755270211524 gnomAD-4.0.0 6.58475E-06 None None None None N None 2.41558E-05 0 None 0 0 None 0 0 0 0 0
I/M 15541 Ig-107 62 rs2057981019 0.291 None 0.998 N 0.676 0.38 0.501559347837 gnomAD-3.1.2 6.59E-06 None None None None N None 0 6.58E-05 0 0 0 None 0 0 0 0 0
I/M 15541 Ig-107 62 rs2057981019 0.291 None 0.998 N 0.676 0.38 0.501559347837 gnomAD-4.0.0 6.58536E-06 None None None None N None 0 6.57549E-05 None 0 0 None 0 0 0 0 0
A/D 15627 Ig-108 60 rs115813214 0.9493 -2.53 0.968 N 0.663 0.61 0.72038618509 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
A/D 15627 Ig-108 60 rs115813214 0.9493 -2.53 0.968 N 0.663 0.61 0.72038618509 gnomAD-4.0.0 6.84837E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65893E-05
A/P 15627 Ig-108 60 None 0.435 None 0.011 N 0.399 0.276 0.260735089382 gnomAD-4.0.0 6.84825E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00019E-07 0 0
A/S 15627 Ig-108 60 None 0.1768 None 0.811 N 0.541 0.224 0.265010934533 gnomAD-4.0.0 6.84825E-07 None None None None N None 0 0 None 0 2.52781E-05 None 0 0 0 0 0
A/T 15627 Ig-108 60 rs1576520581 0.1193 None 0.103 N 0.385 0.245 0.225215365344 gnomAD-4.0.0 6.84825E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65893E-05
A/V 15627 Ig-108 60 rs115813214 0.1849 -0.588 0.811 N 0.571 0.258 None gnomAD-2.1.1 5.66105E-04 None None None None N None 5.92132E-03 3.97886E-04 None 0 0 None 0 None 0 7.84E-06 0
A/V 15627 Ig-108 60 rs115813214 0.1849 -0.588 0.811 N 0.571 0.258 None gnomAD-3.1.2 1.44356E-03 None None None None N None 5.01089E-03 5.91483E-04 0 0 0 None 0 0 0 0 1.44231E-03
A/V 15627 Ig-108 60 rs115813214 0.1849 -0.588 0.811 N 0.571 0.258 None 1000 genomes 7.98722E-04 None None None None N None 3E-03 0 None None 0 0 None None None 0 None
A/V 15627 Ig-108 60 rs115813214 0.1849 -0.588 0.811 N 0.571 0.258 None gnomAD-4.0.0 2.65504E-04 None None None None N None 5.08021E-03 4.34434E-04 None 0 0 None 0 8.27267E-04 1.69644E-06 1.09917E-05 2.24424E-04
S/N 16025 Ig-109 58 rs727504720 0.9448 None 0.999 D 0.632 0.38 0.388010793773 gnomAD-4.0.0 1.59335E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86223E-06 0 0
S/R 16025 Ig-109 58 rs1185643168 0.9924 -0.562 1.0 D 0.739 0.598 0.460795861206 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/R 16025 Ig-109 58 rs1185643168 0.9924 -0.562 1.0 D 0.739 0.598 0.460795861206 gnomAD-4.0.0 1.59335E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43332E-05 0
S/G 17017 Ig-111 63 rs766949350 0.184 -0.74 0.001 N 0.169 0.121 0.115124310173 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
S/G 17017 Ig-111 63 rs766949350 0.184 -0.74 0.001 N 0.169 0.121 0.115124310173 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/G 17017 Ig-111 63 rs766949350 0.184 -0.74 0.001 N 0.169 0.121 0.115124310173 gnomAD-4.0.0 3.84787E-06 None None None None N None 0 0 None 0 0 None 0 0 7.18866E-06 0 0
S/R 17017 Ig-111 63 rs1246257248 0.9882 None 0.773 N 0.649 0.242 0.367803931526 gnomAD-4.0.0 6.8457E-07 None None None None N None 0 0 None 0 2.52691E-05 None 0 0 0 0 0
S/T 17339 Ig-112 89 rs765426395 0.1428 None 0.978 N 0.529 0.153 0.292062946507 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
S/Y 17339 Ig-112 89 None 0.9696 None 0.999 N 0.773 0.469 0.806415548049 gnomAD-4.0.0 1.62947E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.49504E-05 0
A/T 17734 Ig-113 58 None 0.1596 None 0.576 N 0.381 0.263 0.40032279838 gnomAD-4.0.0 1.59228E-06 None None None None N None 0 2.28666E-05 None 0 0 None 0 0 0 0 0
A/V 18035 Ig-114 68 rs182445366 0.1938 -0.464 0.009 N 0.285 0.111 None gnomAD-2.1.1 4.3E-05 None None None None N None 0 5.66E-05 None 1.94401E-04 0 None 0 None 4.01E-05 2.36E-05 5.63222E-04
A/V 18035 Ig-114 68 rs182445366 0.1938 -0.464 0.009 N 0.285 0.111 None gnomAD-3.1.2 1.57992E-04 None None None None N None 7.24E-05 9.85416E-04 0 0 0 None 0 0 5.89E-05 0 9.56023E-04
A/V 18035 Ig-114 68 rs182445366 0.1938 -0.464 0.009 N 0.285 0.111 None 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
A/V 18035 Ig-114 68 rs182445366 0.1938 -0.464 0.009 N 0.285 0.111 None gnomAD-4.0.0 4.03078E-05 None None None None N None 5.33789E-05 3.33712E-04 None 3.04486E-04 0 None 0 0 1.61138E-05 2.1978E-05 1.76203E-04
C/F 19153 Ig-117 59 None 0.9815 None 1.0 N 0.718 0.506 0.838709154919 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
A/D 19449 Ig-118 59 rs1179903616 0.9637 -1.208 0.324 D 0.487 0.464 0.647137792213 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.6E-05 None 0 None 0 0 0
A/D 19449 Ig-118 59 rs1179903616 0.9637 -1.208 0.324 D 0.487 0.464 0.647137792213 gnomAD-4.0.0 1.59179E-06 None None None None N None 0 0 None 0 2.77886E-05 None 0 0 0 0 0
A/P 19449 Ig-118 59 None 0.7192 None 0.773 N 0.551 0.52 0.346085882481 gnomAD-4.0.0 6.84305E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99551E-07 0 0
A/S 19449 Ig-118 59 rs753417375 0.1346 -1.197 0.001 N 0.175 0.139 0.16115917748 gnomAD-2.1.1 1.07E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.35E-05 0
A/S 19449 Ig-118 59 rs753417375 0.1346 -1.197 0.001 N 0.175 0.139 0.16115917748 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/S 19449 Ig-118 59 rs753417375 0.1346 -1.197 0.001 N 0.175 0.139 0.16115917748 gnomAD-4.0.0 5.5783E-06 None None None None N None 0 1.66806E-05 None 0 0 None 0 0 6.78164E-06 0 0
A/V 19449 Ig-118 59 None 0.3372 None 0.193 N 0.449 0.178 0.357724736475 gnomAD-4.0.0 1.59179E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85912E-06 0 0
C/R 20141 Ig-120 62 None 0.9831 None 1.0 N 0.795 0.677 0.885774903276 gnomAD-4.0.0 1.36884E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79938E-06 0 0
A/G 20539 Ig-121 61 None 0.4734 None 1.0 D 0.543 0.631 0.724018906263 gnomAD-4.0.0 1.5924E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02554E-05
A/T 20539 Ig-121 61 rs754756569 0.4131 -1.727 1.0 D 0.715 0.415 0.65076212359 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
A/T 20539 Ig-121 61 rs754756569 0.4131 -1.727 1.0 D 0.715 0.415 0.65076212359 gnomAD-4.0.0 3.18485E-06 None None None None N None 0 0 None 0 2.77855E-05 None 0 0 0 0 3.02554E-05
V/M 21926 Ig-125 61 rs145527033 0.6031 -0.874 1.0 N 0.735 0.549 None gnomAD-2.1.1 3.85833E-04 None None None None N None 2.99202E-03 7.15226E-04 None 0 0 None 6.59E-05 None 4.02E-05 3.95E-05 2.8393E-04
V/M 21926 Ig-125 61 rs145527033 0.6031 -0.874 1.0 N 0.735 0.549 None gnomAD-3.1.2 7.95634E-04 None None None None N None 2.60593E-03 5.89468E-04 0 0 0 None 0 0 5.88E-05 0 0
V/M 21926 Ig-125 61 rs145527033 0.6031 -0.874 1.0 N 0.735 0.549 None 1000 genomes 7.98722E-04 None None None None N None 3E-03 0 None None 0 0 None None None 0 None
V/M 21926 Ig-125 61 rs145527033 0.6031 -0.874 1.0 N 0.735 0.549 None gnomAD-4.0.0 1.8141E-04 None None None None N None 2.37555E-03 6.52851E-04 None 0 2.2483E-05 None 0 0 4.75589E-05 5.53183E-05 2.08708E-04
V/M 22324 Ig-126 60 rs2154176354 0.7086 None 0.997 N 0.707 0.554 0.70371367467 gnomAD-4.0.0 1.36885E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99688E-07 1.15958E-05 0
A/T 23010 Ig-128 61 None 0.1675 None 0.201 N 0.55 0.153 0.186928172975 gnomAD-4.0.0 1.59216E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85982E-06 0 0
A/V 23010 Ig-128 61 rs1575830557 0.2873 None 0.334 N 0.579 0.316 0.355034743287 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
C/S 23405 Ig-129 61 rs1709915221 0.5907 None 0.822 N 0.631 0.463 0.677873887768 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
C/S 23405 Ig-129 61 rs1709915221 0.5907 None 0.822 N 0.631 0.463 0.677873887768 gnomAD-4.0.0 6.57523E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47089E-05 0 0
C/R 23696 Ig-130 60 rs1709557922 0.9874 None 0.996 N 0.646 0.513 0.750170861795 gnomAD-4.0.0 1.59204E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85935E-06 0 0
C/Y 23696 Ig-130 60 None 0.9663 None 0.996 N 0.627 0.444 0.832717335692 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/T 24092 Ig-131 64 None 0.1509 None 0.939 N 0.469 0.251 0.267299060538 gnomAD-4.0.0 6.85447E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00969E-07 0 0
A/P 24778 Ig-133 63 rs761619474 0.905 -1.143 1.0 D 0.802 0.58 0.648841342166 gnomAD-4.0.0 6.84363E-07 None None None None N None 0 0 None 0 0 None 1.8747E-05 0 0 0 0
A/S 24778 Ig-133 63 None 0.1695 None 1.0 N 0.635 0.482 0.49382923527 gnomAD-4.0.0 1.36873E-06 None None None None N None 0 0 None 0 2.52092E-05 None 0 0 8.99599E-07 0 0
A/T 24778 Ig-133 63 rs761619474 0.1828 -1.481 1.0 D 0.775 0.434 None gnomAD-2.1.1 2.02E-05 None None None None N None 6.48E-05 0 None 0 0 None 6.54E-05 None 4.66E-05 8.92E-06 0
A/T 24778 Ig-133 63 rs761619474 0.1828 -1.481 1.0 D 0.775 0.434 None gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 24778 Ig-133 63 rs761619474 0.1828 -1.481 1.0 D 0.775 0.434 None gnomAD-4.0.0 1.48769E-05 None None None None N None 4.00684E-05 0 None 0 0 None 1.56367E-05 0 1.44118E-05 2.19713E-05 1.60169E-05
A/V 24778 Ig-133 63 rs1708284280 0.2689 None 1.0 N 0.715 0.414 0.505211317368 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
A/V 24778 Ig-133 63 rs1708284280 0.2689 None 1.0 N 0.715 0.414 0.505211317368 gnomAD-4.0.0 2.56345E-06 None None None None N None 0 1.6952E-05 None 0 0 None 0 0 0 0 2.84527E-05
A/V 25174 Ig-134 64 rs772038176 0.1927 -0.505 0.955 N 0.659 0.289 0.637886457206 gnomAD-2.1.1 1.07E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.35E-05 0
A/V 25174 Ig-134 64 rs772038176 0.1927 -0.505 0.955 N 0.659 0.289 0.637886457206 gnomAD-4.0.0 4.77585E-06 None None None None N None 0 0 None 0 0 None 0 0 8.57775E-06 0 0
V/I 25571 Ig-135 58 rs760782774 0.152 -0.836 0.997 N 0.492 0.342 0.721245998615 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
A/G 26256 Ig-137 64 None 0.4272 None 1.0 D 0.559 0.655 0.723355570506 gnomAD-4.0.0 6.93041E-07 None None None None N None 0 0 None 0 0 None 0 0 9.04889E-07 0 0
A/P 26256 Ig-137 64 rs765170810 0.9524 None 1.0 N 0.766 0.693 0.731461578019 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/P 26256 Ig-137 64 rs765170810 0.9524 None 1.0 N 0.766 0.693 0.731461578019 gnomAD-4.0.0 6.57402E-06 None None None None N None 2.41313E-05 0 None 0 0 None 0 0 0 0 0
A/T 26256 Ig-137 64 rs765170810 0.2149 -1.509 1.0 D 0.746 0.536 0.652354097294 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06868E-04 0
A/T 26256 Ig-137 64 rs765170810 0.2149 -1.509 1.0 D 0.746 0.536 0.652354097294 gnomAD-4.0.0 3.93976E-06 None None None None N None 0 0 None 0 2.43025E-05 None 0 0 0 2.84034E-05 0
C/Y 26653 Ig-138 60 rs752562709 0.9778 -0.91 0.99 N 0.678 0.613 0.770712332363 gnomAD-2.1.1 2.01E-05 None None None None N None 0 0 None 0 2.78676E-04 None 0 None 0 0 0
C/Y 26653 Ig-138 60 rs752562709 0.9778 -0.91 0.99 N 0.678 0.613 0.770712332363 gnomAD-4.0.0 7.95753E-06 None None None None N None 0 0 None 0 1.38696E-04 None 0 0 0 0 0
G/A 26942 Ig-139 63 rs754062150 0.0686 -0.721 None N 0.188 0.118 0.0884992946249 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
G/A 26942 Ig-139 63 rs754062150 0.0686 -0.721 None N 0.188 0.118 0.0884992946249 gnomAD-4.0.0 6.84265E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99539E-07 0 0
G/V 26942 Ig-139 63 rs754062150 0.228 -0.248 0.024 N 0.561 0.146 0.335661160332 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
G/V 26942 Ig-139 63 rs754062150 0.228 -0.248 0.024 N 0.561 0.146 0.335661160332 gnomAD-4.0.0 6.84265E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99539E-07 0 0
C/Y 27339 Ig-140 62 None 0.9588 None 0.999 N 0.789 0.417 0.764677420096 gnomAD-4.0.0 4.10525E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49748E-06 0 1.65667E-05
V/A 27736 Ig-141 61 rs1370518448 0.5539 None 0.63 N 0.526 0.362 0.698509492642 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/A 27736 Ig-141 61 rs1370518448 0.5539 None 0.63 N 0.526 0.362 0.698509492642 gnomAD-4.0.0 2.56282E-06 None None None None N None 0 0 None 4.09065E-05 0 None 0 0 2.39335E-06 0 0
V/F 27736 Ig-141 61 rs373638788 0.9612 -1.609 0.983 D 0.72 0.691 0.839994840878 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
V/F 27736 Ig-141 61 rs373638788 0.9612 -1.609 0.983 D 0.72 0.691 0.839994840878 gnomAD-4.0.0 2.73718E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59801E-06 0 0
V/I 27736 Ig-141 61 rs373638788 0.1776 -0.849 0.873 N 0.53 0.362 0.614010665196 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
V/I 27736 Ig-141 61 rs373638788 0.1776 -0.849 0.873 N 0.53 0.362 0.614010665196 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 27736 Ig-141 61 rs373638788 0.1776 -0.849 0.873 N 0.53 0.362 0.614010665196 gnomAD-4.0.0 6.19775E-06 None None None None N None 0 0 None 0 0 None 0 0 8.47634E-06 0 0
V/L 27736 Ig-141 61 None 0.7962 None 0.773 N 0.537 0.479 0.727553539088 gnomAD-4.0.0 1.36859E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.31873E-05 0
A/T 28025 Ig-142 63 rs372956981 0.1553 -1.998 1.0 D 0.681 0.409 None gnomAD-2.1.1 1.62E-05 None None None None N None 1.2987E-04 0 None 0 0 None 0 None 0 1.79E-05 0
A/T 28025 Ig-142 63 rs372956981 0.1553 -1.998 1.0 D 0.681 0.409 None gnomAD-3.1.2 1.97E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 2.94E-05 0 0
A/T 28025 Ig-142 63 rs372956981 0.1553 -1.998 1.0 D 0.681 0.409 None gnomAD-4.0.0 9.29798E-06 None None None None N None 4.00491E-05 0 None 0 0 None 0 0 9.32483E-06 1.09835E-05 0
A/V 28025 Ig-142 63 None 0.1959 None 1.0 N 0.625 0.403 0.550632123912 gnomAD-4.0.0 1.59237E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85945E-06 0 0
C/R 28420 Ig-143 63 rs773918512 0.9463 -0.496 0.988 N 0.579 0.458 0.811669667423 gnomAD-2.1.1 1.43E-05 None None None None N None 0 0 None 0 1.54575E-04 None 0 None 0 7.81E-06 0
C/R 28420 Ig-143 63 rs773918512 0.9463 -0.496 0.988 N 0.579 0.458 0.811669667423 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
C/R 28420 Ig-143 63 rs773918512 0.9463 -0.496 0.988 N 0.579 0.458 0.811669667423 gnomAD-4.0.0 5.12502E-06 None None None None N None 0 0 None 0 4.85932E-05 None 0 0 4.78563E-06 0 0
S/N 29107 Ig-145 63 None 0.7639 None 0.999 N 0.654 0.339 0.372268306217 gnomAD-4.0.0 1.36833E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99416E-07 1.15931E-05 0
A/S 29503 Ig-146 60 rs1403452380 0.1508 None 0.865 N 0.509 0.293 0.324986149311 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/S 29503 Ig-146 60 rs1403452380 0.1508 None 0.865 N 0.509 0.293 0.324986149311 gnomAD-4.0.0 6.57151E-06 None None None None N None 2.41243E-05 0 None 0 0 None 0 0 0 0 0
A/T 29503 Ig-146 60 rs1403452380 0.1141 None 0.039 N 0.311 0.194 0.275641507738 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 29503 Ig-146 60 rs1403452380 0.1141 None 0.039 N 0.311 0.194 0.275641507738 gnomAD-4.0.0 5.07471E-06 None None None None N None 0 0 None 0 0 None 0 0 6.02456E-06 0 0
A/V 29503 Ig-146 60 rs1224421468 0.2332 -0.534 0.865 N 0.575 0.287 0.536287059136 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
A/V 29503 Ig-146 60 rs1224421468 0.2332 -0.534 0.865 N 0.575 0.287 0.536287059136 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/V 29503 Ig-146 60 rs1224421468 0.2332 -0.534 0.865 N 0.575 0.287 0.536287059136 gnomAD-4.0.0 6.57263E-06 None None None None N None 2.41324E-05 0 None 0 0 None 0 0 0 0 0
A/S 30194 Ig-148 63 rs879039246 0.154 -1.707 0.001 N 0.368 0.166 0.286465849087 gnomAD-2.1.1 4.09E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9E-06 0
A/S 30194 Ig-148 63 rs879039246 0.154 -1.707 0.001 N 0.368 0.166 0.286465849087 gnomAD-4.0.0 1.6008E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86944E-06 0 0
A/V 30194 Ig-148 63 rs1198317987 0.0918 -0.491 None N 0.212 0.164 0.0716867268079 gnomAD-2.1.1 4.09E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.99E-06 0
A/V 30194 Ig-148 63 rs1198317987 0.0918 -0.491 None N 0.212 0.164 0.0716867268079 gnomAD-4.0.0 1.60004E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86847E-06 0 0
A/T 30589 Ig-149 58 rs148617456 0.1368 -1.22 1.0 N 0.733 0.416 None gnomAD-2.1.1 3.38986E-03 None None None None N None 2.0668E-04 7.63488E-04 None 1.0626E-03 1.02501E-04 None 2.17036E-02 None 4E-05 1.70981E-03 2.9453E-03
A/T 30589 Ig-149 58 rs148617456 0.1368 -1.22 1.0 N 0.733 0.416 None gnomAD-3.1.2 1.77459E-03 None None None None N None 2.41336E-04 1.83438E-03 0 8.64553E-04 0 None 0 0 1.64653E-03 2.34148E-02 1.91205E-03
A/T 30589 Ig-149 58 rs148617456 0.1368 -1.22 1.0 N 0.733 0.416 None 1000 genomes 5.99042E-03 None None None None N None 0 1.4E-03 None None 0 2E-03 None None None 2.76E-02 None
A/T 30589 Ig-149 58 rs148617456 0.1368 -1.22 1.0 N 0.733 0.416 None gnomAD-4.0.0 2.17191E-03 None None None None N None 3.19915E-04 9.83268E-04 None 8.44709E-04 1.56027E-04 None 6.24785E-05 4.12541E-03 1.05784E-03 2.11916E-02 2.92922E-03
C/R 30986 Ig-150 60 None 0.9882 None 1.0 N 0.77 0.657 0.854901379662 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
C/S 30986 Ig-150 60 rs1181542972 0.4307 -0.405 1.0 N 0.711 0.546 0.712579179446 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
C/S 30986 Ig-150 60 rs1181542972 0.4307 -0.405 1.0 N 0.711 0.546 0.712579179446 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
C/R 31678 Ig-152 58 rs2555818 0.993 None 1.0 N 0.802 0.729 0.863481631396 gnomAD-4.0.0 1.59126E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85838E-06 0 0
C/Y 31678 Ig-152 58 None 0.9946 None 1.0 N 0.803 0.529 0.794249481724 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/I 32369 Ig-154 63 rs559194338 0.8063 0.172 0.056 N 0.416 0.306 0.363356657567 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
T/I 32369 Ig-154 63 rs559194338 0.8063 0.172 0.056 N 0.416 0.306 0.363356657567 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
T/I 32369 Ig-154 63 rs559194338 0.8063 0.172 0.056 N 0.416 0.306 0.363356657567 1000 genomes 3.99361E-04 None None None None N None 1.5E-03 0 None None 0 0 None None None 0 None
T/I 32369 Ig-154 63 rs559194338 0.8063 0.172 0.056 N 0.416 0.306 0.363356657567 gnomAD-4.0.0 1.85898E-06 None None None None N None 3.99893E-05 0 None 0 0 None 0 0 0 0 0
T/N 32369 Ig-154 63 None 0.6375 None 0.994 N 0.622 0.437 0.562316820711 gnomAD-4.0.0 1.36843E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79897E-06 0 0
T/S 32369 Ig-154 63 None 0.2334 None 0.805 N 0.475 0.216 0.267299060538 gnomAD-4.0.0 1.59122E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85829E-06 0 0
A/G 32765 Ig-155 58 rs72648273 0.4162 -1.504 1.0 D 0.545 0.411 None gnomAD-2.1.1 2.97035E-03 None None None None N None 2.894E-04 1.47125E-03 None 5.12473E-03 0 None 1.07843E-03 None 4.79655E-03 4.27424E-03 2.80505E-03
A/G 32765 Ig-155 58 rs72648273 0.4162 -1.504 1.0 D 0.545 0.411 None gnomAD-3.1.2 2.47186E-03 None None None None N None 4.82835E-04 3.01402E-03 0 2.88184E-03 0 None 3.95704E-03 3.16456E-03 3.63171E-03 8.27815E-04 2.87081E-03
A/G 32765 Ig-155 58 rs72648273 0.4162 -1.504 1.0 D 0.545 0.411 None 1000 genomes 9.98403E-04 None None None None N None 0 2.9E-03 None None 0 2E-03 None None None 1E-03 None
A/G 32765 Ig-155 58 rs72648273 0.4162 -1.504 1.0 D 0.545 0.411 None gnomAD-4.0.0 2.89938E-03 None None None None N None 4.93241E-04 1.90006E-03 None 3.54706E-03 2.22896E-05 None 4.21809E-03 4.28901E-03 3.25911E-03 1.09786E-03 2.89693E-03
A/T 32765 Ig-155 58 rs971287235 0.2699 None 1.0 D 0.683 0.349 0.538514308947 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 32765 Ig-155 58 rs971287235 0.2699 None 1.0 D 0.683 0.349 0.538514308947 gnomAD-4.0.0 6.57272E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4702E-05 0 0
I/M 34199 Ig-160 63 rs749009190 0.2189 -1.193 0.968 D 0.605 0.444 0.564429724435 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 4.64E-05 0 0
I/M 34199 Ig-160 63 rs749009190 0.2189 -1.193 0.968 D 0.605 0.444 0.564429724435 gnomAD-4.0.0 3.182E-06 None None None None N None 0 0 None 0 0 None 3.76605E-05 0 0 0 0
I/V 34199 Ig-160 63 rs56347248 0.1107 -1.471 0.437 N 0.453 0.126 None gnomAD-2.1.1 3.38351E-03 None None None None N None 1.23967E-04 7.63964E-04 None 1.0626E-03 0 None 2.17334E-02 None 4E-05 1.72247E-03 2.94118E-03
I/V 34199 Ig-160 63 rs56347248 0.1107 -1.471 0.437 N 0.453 0.126 None gnomAD-3.1.2 1.72112E-03 None None None None N None 1.68789E-04 1.6357E-03 0 8.64055E-04 0 None 0 0 1.64628E-03 2.31884E-02 1.43541E-03
I/V 34199 Ig-160 63 rs56347248 0.1107 -1.471 0.437 N 0.453 0.126 None 1000 genomes 5.99042E-03 None None None None N None 0 1.4E-03 None None 0 2E-03 None None None 2.76E-02 None
I/V 34199 Ig-160 63 rs56347248 0.1107 -1.471 0.437 N 0.453 0.126 None gnomAD-4.0.0 2.16048E-03 None None None None N None 2.39783E-04 9.33022E-04 None 8.44423E-04 4.45593E-05 None 6.2498E-05 4.12405E-03 1.06368E-03 2.12336E-02 2.6886E-03
V/G 34323 Ig-161 66 rs1307866503 0.8767 None 0.995 D 0.715 0.7 0.867032782884 gnomAD-4.0.0 1.59099E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85763E-06 0 0
T/I 34426 Ig-162 64 rs375049689 0.8188 -0.079 1.0 N 0.797 0.418 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
T/P 34426 Ig-162 64 None 0.7059 None 1.0 N 0.8 0.562 0.42828666871 gnomAD-4.0.0 1.59151E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85763E-06 0 0
V/A 35191 Ig-164 63 None 0.3572 None 0.999 N 0.543 0.486 0.673800983336 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/I 35191 Ig-164 63 rs1290162863 0.1256 -0.746 0.997 D 0.523 0.369 0.685586197109 gnomAD-2.1.1 7.13E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.56E-05 0
V/I 35191 Ig-164 63 rs1290162863 0.1256 -0.746 0.997 D 0.523 0.369 0.685586197109 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 35191 Ig-164 63 rs1290162863 0.1256 -0.746 0.997 D 0.523 0.369 0.685586197109 gnomAD-4.0.0 2.35457E-05 None None None None N None 1.33504E-05 0 None 0 0 None 0 0 2.96635E-05 0 3.20174E-05
L/F 35349 Ig-165 64 rs1220665174 0.4413 None 0.999 N 0.786 0.29 0.662113396273 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/F 35349 Ig-165 64 rs1220665174 0.4413 None 0.999 N 0.786 0.29 0.662113396273 gnomAD-4.0.0 6.57151E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47007E-05 0 0
L/I 35349 Ig-165 64 rs1220665174 0.1208 None 0.984 N 0.551 0.157 0.514358602855 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
L/I 35349 Ig-165 64 rs1220665174 0.1208 None 0.984 N 0.551 0.157 0.514358602855 gnomAD-4.0.0 6.57151E-06 None None None None N None 0 6.54793E-05 None 0 0 None 0 0 0 0 0
T/A 35482 Ig-166 63 rs1423470146 0.1216 -0.134 0.114 N 0.23 0.208 0.173771789658 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.33E-05 None 0 0 0
T/A 35482 Ig-166 63 rs1423470146 0.1216 -0.134 0.114 N 0.23 0.208 0.173771789658 gnomAD-4.0.0 1.59654E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.44932E-05 0
T/S 35482 Ig-166 63 rs1423470146 0.206 None 0.664 N 0.513 0.148 0.256793551483 gnomAD-4.0.0 3.19307E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72452E-06 0 0
A/S 35764 Ig-168 63 rs879048717 0.2145 -0.854 0.998 N 0.663 0.433 0.338592109245 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
A/S 35764 Ig-168 63 rs879048717 0.2145 -0.854 0.998 N 0.663 0.433 0.338592109245 gnomAD-4.0.0 1.71041E-05 None None None None N None 0 0 None 0 0 None 0 0 2.24855E-05 0 0
V/A 35961 Ig-169 65 None 0.7078 None 0.581 N 0.515 0.403 0.652866637519 gnomAD-4.0.0 1.20032E-06 None None None -0.982(OBSL1) -0.734(OBSCN) N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/I 35961 Ig-169 65 None 0.1235 -1.202 0.024 N 0.314 0.114 None gnomAD-2.1.1 4.01E-06 None None None -1.469(OBSL1) -1.143(OBSCN) N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
V/I 35961 Ig-169 65 None 0.1235 -1.202 0.024 N 0.314 0.114 None gnomAD-3.1.2 1.97E-05 None None None -1.469(OBSL1) -1.143(OBSCN) N None 0 6.55E-05 0 0 0 None 0 0 1.47E-05 0 4.79386E-04
V/I 35961 Ig-169 65 None 0.1235 -1.202 0.024 N 0.314 0.114 None gnomAD-4.0.0 9.29492E-06 None None None -1.469(OBSL1) -1.143(OBSCN) N None 2.67023E-05 3.33367E-05 None 0 0 None 0 0 5.9329E-06 1.09794E-05 4.80323E-05
V/L 35961 Ig-169 65 rs780886524 0.7518 -1.197 0.201 D 0.489 0.344 0.503311249505 gnomAD-2.1.1 1.2E-05 None None None -1.469(OBSL1) -1.143(OBSCN) N None 0 0 None 0 0 None 0 None 0 1.77E-05 1.65235E-04
V/L 35961 Ig-169 65 rs780886524 0.7518 -1.197 0.201 D 0.489 0.344 0.503311249505 gnomAD-3.1.2 6.57E-06 None None None -1.469(OBSL1) -1.143(OBSCN) N None 0 0 0 0 0 None 9.43E-05 0 0 0 0
V/L 35961 Ig-169 65 rs780886524 0.7518 -1.197 0.201 D 0.489 0.344 0.503311249505 gnomAD-4.0.0 1.85898E-06 None None None -1.469(OBSL1) -1.143(OBSCN) N None 0 0 None 0 0 None 0 0 2.54267E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.