Structural position:
- Domain Type: Ig
- Aligned Position: 156
- Secondary Structure Element: e
- Secondary Structure Region: β-strand F
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V/A | 176 |
Ig-2 |
73 | None | 0.7365 | None | 0.999 | N | 0.731 | 0.601 | 0.732523770267 | gnomAD-4.0.0 | 1.59045E-06 | None | None | None | -0.768(TCAP) | N | None | 0 | 0 | None | 0 | 2.77239E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 176 |
Ig-2 |
73 | None | 0.1825 | None | 0.995 | N | 0.588 | 0.362 | 0.722692856958 | gnomAD-4.0.0 | 6.84061E-07 | None | None | None | -1.347(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99295E-07 | 0 | 0 |
| V/L | 176 |
Ig-2 |
73 | rs941179323 |
0.8051 | 0.026 | 0.987 | D | 0.705 | 0.537 | 0.676533949136 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | -1.347(TCAP) | N | None | 1.20668E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 176 |
Ig-2 |
73 | rs941179323 |
0.8051 | 0.026 | 0.987 | D | 0.705 | 0.537 | 0.676533949136 | gnomAD-4.0.0 | 6.84061E-07 | None | None | None | -1.347(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| I/T | 1156 |
Ig-4 |
75 | None | 0.9234 | None | 0.722 | N | 0.74 | 0.339 | 0.537170616986 | gnomAD-4.0.0 | 2.73646E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59733E-06 | 0 | 0 |
| I/V | 1156 |
Ig-4 |
75 | None | 0.082 | None | 0.003 | N | 0.303 | 0.057 | 0.229924730088 | gnomAD-4.0.0 | 1.59076E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76644E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 1364 |
Ig-5 |
74 | rs1171035485 |
0.4127 | -0.94 | 0.977 | N | 0.745 | 0.301 | 0.335414705075 | gnomAD-2.1.1 | 1.99E-05 | None | None | None | None | N | None | 0 | 1.44617E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 1364 |
Ig-5 |
74 | rs1171035485 |
0.4127 | -0.94 | 0.977 | N | 0.745 | 0.301 | 0.335414705075 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.30959E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 1364 |
Ig-5 |
74 | rs1171035485 |
0.4127 | -0.94 | 0.977 | N | 0.745 | 0.301 | 0.335414705075 | gnomAD-4.0.0 | 1.40886E-05 | None | None | None | None | N | None | 0 | 1.69474E-04 | None | 0 | 0 | None | 0 | 0 | 2.3921E-06 | 0 | 0 |
| A/V | 1630 |
Ig-7 |
75 | rs371601918 |
0.647 | 0.645 | 0.252 | N | 0.403 | 0.223 | 0.43046518545 | gnomAD-2.1.1 | 8E-06 | None | None | None | None | N | None | 6.28E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.85E-06 | 0 |
| A/V | 1630 |
Ig-7 |
75 | rs371601918 |
0.647 | 0.645 | 0.252 | N | 0.403 | 0.223 | 0.43046518545 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/V | 1630 |
Ig-7 |
75 | rs371601918 |
0.647 | 0.645 | 0.252 | N | 0.403 | 0.223 | 0.43046518545 | gnomAD-4.0.0 | 8.05554E-06 | None | None | None | None | N | None | 5.34117E-05 | 0 | None | 0 | 8.91663E-05 | None | 0 | 1.64366E-04 | 2.54242E-06 | 0 | 1.60056E-05 |
| C/F | 1777 |
Ig-8 |
75 | None | 0.9898 | None | 1.0 | D | 0.88 | 0.87 | 0.888915657287 | gnomAD-4.0.0 | 1.59922E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.00924E-05 | 0 | 0 | 0 | 0 |
| C/R | 1777 |
Ig-8 |
75 | rs2092247232 |
0.9996 | None | 1.0 | D | 0.892 | 0.908 | 0.89891181745 | gnomAD-4.0.0 | 6.85596E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99313E-07 | 0 | 0 |
| V/A | 2151 |
Ig-10 |
74 | None | 0.4958 | None | 0.999 | D | 0.775 | 0.657 | 0.776336265085 | gnomAD-4.0.0 | 1.59066E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| V/I | 2151 |
Ig-10 |
74 | rs755654942 |
0.1845 | -0.666 | 0.997 | D | 0.602 | 0.449 | 0.826952020868 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.46E-05 | None | 0 | None | 0 | 0 | 0 |
| V/I | 2151 |
Ig-10 |
74 | rs755654942 |
0.1845 | -0.666 | 0.997 | D | 0.602 | 0.449 | 0.826952020868 | gnomAD-4.0.0 | 1.59065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85651E-06 | 0 | 0 |
| C/G | 2246 |
Ig-11 |
73 | rs1484766954 |
0.9524 | None | 1.0 | D | 0.915 | 0.627 | 0.731798775535 | gnomAD-2.1.1 | 3.98E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.82E-06 | 0 |
| C/G | 2246 |
Ig-11 |
73 | rs1484766954 |
0.9524 | None | 1.0 | D | 0.915 | 0.627 | 0.731798775535 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/G | 2246 |
Ig-11 |
73 | rs1484766954 |
0.9524 | None | 1.0 | D | 0.915 | 0.627 | 0.731798775535 | gnomAD-4.0.0 | 3.84249E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.17652E-06 | 0 | 0 |
| F/S | 2604 |
Ig-15 |
72 | rs772001227 |
0.9801 | -3.122 | 0.991 | D | 0.864 | 0.615 | 0.694515167275 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| F/S | 2604 |
Ig-15 |
72 | rs772001227 |
0.9801 | -3.122 | 0.991 | D | 0.864 | 0.615 | 0.694515167275 | gnomAD-4.0.0 | 1.59108E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85709E-06 | 0 | 0 |
| Y/D | 2691 |
Ig-16 |
71 | rs1257930872 |
0.9946 | None | 0.916 | N | 0.862 | 0.456 | 0.482209950775 | gnomAD-4.0.0 | 3.18125E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71318E-06 | 0 | 0 |
| Y/H | 2691 |
Ig-16 |
71 | None | 0.9232 | None | 0.916 | N | 0.686 | 0.4 | 0.272205846399 | gnomAD-4.0.0 | 1.59062E-06 | None | None | None | None | N | None | 0 | 2.28686E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 2866 |
Ig-18 |
72 | rs147174853 |
0.3509 | -1.9 | 1.0 | N | 0.78 | 0.44 | None | gnomAD-2.1.1 | 1.59E-05 | None | None | None | None | N | None | 2.46063E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 2866 |
Ig-18 |
72 | rs147174853 |
0.3509 | -1.9 | 1.0 | N | 0.78 | 0.44 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 2866 |
Ig-18 |
72 | rs147174853 |
0.3509 | -1.9 | 1.0 | N | 0.78 | 0.44 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| A/T | 2866 |
Ig-18 |
72 | rs147174853 |
0.3509 | -1.9 | 1.0 | N | 0.78 | 0.44 | None | gnomAD-4.0.0 | 3.71718E-06 | None | None | None | None | N | None | 7.99659E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 3416 |
Ig-24 |
72 | None | 0.9427 | None | 0.826 | N | 0.671 | 0.416 | 0.543254643676 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/S | 3539 |
Ig-25 |
75 | rs750647730 |
0.9535 | -2.256 | None | None | None | 0.595 | None | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/S | 3539 |
Ig-25 |
75 | rs750647730 |
0.9535 | -2.256 | None | None | None | 0.595 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 3539 |
Ig-25 |
75 | rs750647730 |
0.9535 | -2.256 | None | None | None | 0.595 | None | gnomAD-4.0.0 | 1.24271E-06 | None | None | None | None | N | None | 1.33676E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60617E-05 |
| C/W | 3539 |
Ig-25 |
75 | None | 0.9891 | None | None | None | None | 0.53 | None | gnomAD-4.0.0 | 6.86226E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02042E-07 | 0 | 0 |
| C/Y | 3539 |
Ig-25 |
75 | None | 0.9735 | None | None | None | None | 0.52 | None | gnomAD-4.0.0 | 1.37246E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80401E-06 | 0 | 0 |
| C/R | 3732 |
Ig-26 |
73 | None | 0.9681 | None | None | None | None | 0.521 | None | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 3892 |
Ig-27 |
73 | None | 0.8622 | None | 1.0 | D | 0.835 | 0.708 | None | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85806E-06 | 0 | 0 |
| C/R | 4677 |
Ig-29 |
72 | None | 0.9829 | None | 1.0 | D | 0.92 | 0.762 | None | gnomAD-4.0.0 | 1.43192E-06 | None | None | None | None | N | None | 6.30398E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 4677 |
Ig-29 |
72 | None | 0.8771 | None | 1.0 | D | 0.817 | 0.766 | None | gnomAD-4.0.0 | 1.43192E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.85561E-06 | 0 | 0 |
| C/F | 4867 |
Ig-31 |
73 | rs2081352465 |
0.7812 | None | 1.0 | D | 0.887 | 0.676 | 0.851595499224 | gnomAD-4.0.0 | 3.18258E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71615E-06 | 0 | 0 |
| C/G | 4960 |
Ig-32 |
73 | rs879004875 |
0.5477 | -2.37 | 1.0 | D | 0.879 | 0.74 | 0.882974859256 | gnomAD-2.1.1 | 8.11E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| C/G | 4960 |
Ig-32 |
73 | rs879004875 |
0.5477 | -2.37 | 1.0 | D | 0.879 | 0.74 | 0.882974859256 | gnomAD-3.1.2 | 1.31E-05 | None | None | disulfide | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/G | 4960 |
Ig-32 |
73 | rs879004875 |
0.5477 | -2.37 | 1.0 | D | 0.879 | 0.74 | 0.882974859256 | gnomAD-4.0.0 | 7.44486E-06 | None | None | disulfide | None | N | None | 1.33883E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32712E-06 | 0 | 0 |
| C/R | 4960 |
Ig-32 |
73 | rs879004875 |
0.9839 | None | 1.0 | D | 0.904 | 0.72 | None | gnomAD-4.0.0 | 4.79572E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29878E-06 | 0 | 0 |
| C/Y | 4960 |
Ig-32 |
73 | None | 0.8897 | None | 1.0 | D | 0.907 | 0.592 | 0.877724292498 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/R | 5054 |
Ig-33 |
74 | None | 0.9971 | None | 1.0 | D | 0.899 | 0.758 | 0.856532632862 |
Rees (2021)
| None |
CFTD
|
comp het with Y24599Mfs*12 (in trans) | disulfide | None | N | Genetic analysis of TTN in 30 CM patients; comp het with truncating; Protein unfolded | None | None | None | None | None | None | None | None | None | None | None |
| C/R | 5054 |
Ig-33 |
74 | None | 0.9971 | None | 1.0 | D | 0.899 | 0.758 | 0.856532632862 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 5054 |
Ig-33 |
74 | None | 0.9928 | None | 1.0 | D | 0.897 | 0.716 | 0.79540345994 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 5147 |
Ig-34 |
73 | rs1159353292 |
0.9614 | -1.408 | 0.999 | D | 0.855 | 0.751 | 0.878624890865 | gnomAD-2.1.1 | 4.03E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| C/Y | 5147 |
Ig-34 |
73 | rs1159353292 |
0.9614 | -1.408 | 0.999 | D | 0.855 | 0.751 | 0.878624890865 | gnomAD-4.0.0 | 1.5943E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4367E-05 | 0 |
| C/G | 5240 |
Ig-35 |
73 | None | 0.8245 | None | 1.0 | D | 0.861 | 0.747 | 0.905871212908 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/F | 5429 |
Ig-37 |
73 | None | 0.9127 | None | 1.0 | D | 0.884 | 0.516 | 0.854936444189 | gnomAD-4.0.0 | 1.59259E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02663E-05 |
| C/Y | 5429 |
Ig-37 |
73 | None | 0.9885 | None | 1.0 | D | 0.897 | 0.516 | 0.810734245384 | gnomAD-4.0.0 | 1.59259E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85966E-06 | 0 | 0 |
| C/G | 5522 |
Ig-38 |
73 | rs2080729558 |
0.8107 | None | 0.98 | D | 0.853 | 0.662 | 0.868008026345 | gnomAD-4.0.0 | 1.36858E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52092E-05 | None | 0 | 0 | 8.9953E-07 | 0 | 0 |
| C/S | 5522 |
Ig-38 |
73 | None | 0.9379 | None | 0.659 | D | 0.631 | 0.578 | 0.733669960825 | gnomAD-4.0.0 | 1.36858E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79906E-06 | 0 | 0 |
| C/R | 5616 |
Ig-39 |
74 | None | 0.9911 | None | 1.0 | D | 0.897 | 0.673 | 0.873153760803 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 5616 |
Ig-39 |
74 | rs1170057251 |
0.9557 | None | 1.0 | D | 0.899 | 0.563 | 0.842083799564 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 5616 |
Ig-39 |
74 | rs1170057251 |
0.9557 | None | 1.0 | D | 0.899 | 0.563 | 0.842083799564 | gnomAD-4.0.0 | 2.02985E-06 | None | None | disulfide | None | N | None | 1.74709E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.40229E-05 |
| C/W | 6178 |
Ig-45 |
74 | rs1560777515 |
0.9819 | None | 1.0 | D | 0.866 | 0.713 | 0.846997931514 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| C/W | 6178 |
Ig-45 |
74 | rs1560777515 |
0.9819 | None | 1.0 | D | 0.866 | 0.713 | 0.846997931514 | gnomAD-4.0.0 | 1.59136E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 2.77285E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 6178 |
Ig-45 |
74 | rs760469804 |
0.9722 | -1.619 | 1.0 | D | 0.899 | 0.599 | 0.895021782458 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| C/G | 6271 |
Ig-46 |
73 | rs2079970402 |
0.8136 | None | 1.0 | D | 0.882 | 0.782 | 0.878498160798 | gnomAD-4.0.0 | 1.59192E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85964E-06 | 0 | 0 |
| C/Y | 6271 |
Ig-46 |
73 | None | 0.9609 | None | 1.0 | D | 0.909 | 0.708 | 0.817822398108 | gnomAD-4.0.0 | 1.59205E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41896E-04 | 0 | 0 | 0 |
| C/Y | 6364 |
Ig-47 |
73 | None | 0.9506 | None | 1.0 | D | 0.9 | 0.649 | 0.85943983745 | gnomAD-4.0.0 | 6.85015E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00113E-07 | 0 | 0 |
| F/I | 6457 |
Ig-48 |
73 | None | 0.6851 | None | 0.961 | N | 0.735 | 0.213 | 0.382761230579 | gnomAD-4.0.0 | 1.59309E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8608E-06 | 0 | 0 |
| F/L | 6457 |
Ig-48 |
73 | rs2079784971 |
0.9514 | None | 0.135 | N | 0.437 | 0.113 | 0.260735089382 | gnomAD-4.0.0 | 1.59322E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86103E-06 | 0 | 0 |
| F/S | 6457 |
Ig-48 |
73 | rs2079785463 |
0.9895 | None | 0.997 | N | 0.815 | 0.546 | 0.42748209135 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| C/F | 6553 |
Ig-49 |
73 | None | 0.6975 | None | 1.0 | D | 0.892 | 0.698 | 0.872414856674 | gnomAD-4.0.0 | 1.60017E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87465E-06 | 0 | 0 |
| C/G | 6553 |
Ig-49 |
73 | rs377449031 |
0.807 | None | 1.0 | D | 0.874 | 0.753 | 0.905126728963 | gnomAD-4.0.0 | 1.59863E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8717E-06 | 0 | 0 |
| C/R | 6553 |
Ig-49 |
73 | rs377449031 |
0.9881 | -1.373 | 1.0 | D | 0.903 | 0.764 | None | gnomAD-2.1.1 | 4.07E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.99E-06 | 0 |
| C/R | 6553 |
Ig-49 |
73 | rs377449031 |
0.9881 | -1.373 | 1.0 | D | 0.903 | 0.764 | None | gnomAD-4.0.0 | 1.59863E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8717E-06 | 0 | 0 |
| C/Y | 6646 |
Ig-50 |
73 | rs575692993 |
0.9236 | -1.63 | 1.0 | D | 0.914 | 0.579 | 0.810174296794 | gnomAD-2.1.1 | 1.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.03079E-04 | None | 0 | 0 | 0 |
| C/Y | 6646 |
Ig-50 |
73 | rs575692993 |
0.9236 | -1.63 | 1.0 | D | 0.914 | 0.579 | 0.810174296794 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06954E-04 | 0 |
| C/Y | 6646 |
Ig-50 |
73 | rs575692993 |
0.9236 | -1.63 | 1.0 | D | 0.914 | 0.579 | 0.810174296794 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| C/Y | 6646 |
Ig-50 |
73 | rs575692993 |
0.9236 | -1.63 | 1.0 | D | 0.914 | 0.579 | 0.810174296794 | gnomAD-4.0.0 | 3.7348E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.47417E-05 | 3.21657E-05 |
| C/R | 6740 |
Ig-51 |
74 | rs1232772786 |
0.9979 | -1.1 | 1.0 | D | 0.895 | 0.742 | 0.867609169854 | gnomAD-2.1.1 | 4.07E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.33E-05 | None | 0 | 0 | 0 |
| C/R | 6740 |
Ig-51 |
74 | rs1232772786 |
0.9979 | -1.1 | 1.0 | D | 0.895 | 0.742 | 0.867609169854 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| C/R | 6740 |
Ig-51 |
74 | rs1232772786 |
0.9979 | -1.1 | 1.0 | D | 0.895 | 0.742 | 0.867609169854 | gnomAD-4.0.0 | 2.49075E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.51193E-07 | 3.34665E-05 | 0 |
| C/Y | 6740 |
Ig-51 |
74 | rs1414995502 |
0.9944 | -1.284 | 1.0 | D | 0.893 | 0.533 | 0.811632395055 | gnomAD-2.1.1 | 3.19E-05 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| C/Y | 6740 |
Ig-51 |
74 | rs1414995502 |
0.9944 | -1.284 | 1.0 | D | 0.893 | 0.533 | 0.811632395055 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 6740 |
Ig-51 |
74 | rs1414995502 |
0.9944 | -1.284 | 1.0 | D | 0.893 | 0.533 | 0.811632395055 | gnomAD-4.0.0 | 2.58983E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.84754E-06 | 0 | 0 |
| C/R | 6833 |
Ig-52 |
73 | None | 0.9943 | None | 0.975 | D | 0.743 | 0.853 | 0.896977869265 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| C/Y | 6833 |
Ig-52 |
73 | rs2079243325 |
0.9778 | None | 1.0 | D | 0.861 | 0.684 | 0.912907702155 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 6833 |
Ig-52 |
73 | rs2079243325 |
0.9778 | None | 1.0 | D | 0.861 | 0.684 | 0.912907702155 | gnomAD-4.0.0 | 6.57237E-06 | None | None | disulfide | None | N | None | 0 | 6.55394E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 6927 |
Ig-53 |
74 | rs767021612 |
0.9954 | -1.112 | 1.0 | D | 0.907 | 0.795 | 0.865491910662 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| F/L | 7020 |
Ig-54 |
73 | None | 0.9549 | None | 0.989 | N | 0.685 | 0.289 | 0.26547132957 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| F/S | 7020 |
Ig-54 |
73 | rs1377671005 |
0.9887 | None | 0.998 | N | 0.805 | 0.432 | 0.673376435606 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 7020 |
Ig-54 |
73 | rs1377671005 |
0.9887 | None | 0.998 | N | 0.805 | 0.432 | 0.673376435606 | gnomAD-4.0.0 | 6.08958E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.13456E-04 | None | 0 | 0 | 6.02472E-06 | 0 | 0 |
| C/W | 7116 |
Ig-55 |
73 | rs750661972 |
0.9929 | -1.64 | 1.0 | D | 0.861 | 0.513 | 0.468753983522 | gnomAD-2.1.1 | 4.03E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| C/W | 7116 |
Ig-55 |
73 | rs750661972 |
0.9929 | -1.64 | 1.0 | D | 0.861 | 0.513 | 0.468753983522 | gnomAD-4.0.0 | 6.84374E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 2.52003E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 7395 |
Ig-58 |
73 | None | 0.9943 | None | 1.0 | D | 0.845 | 0.689 | 0.860195380671 | gnomAD-4.0.0 | 2.40064E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| C/Y | 7681 |
Ig-61 |
74 | rs573529663 |
0.9919 | -1.386 | 1.0 | D | 0.899 | 0.565 | 0.859650565826 | gnomAD-2.1.1 | 4.03E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| C/Y | 7681 |
Ig-61 |
74 | rs573529663 |
0.9919 | -1.386 | 1.0 | D | 0.899 | 0.565 | 0.859650565826 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 7681 |
Ig-61 |
74 | rs573529663 |
0.9919 | -1.386 | 1.0 | D | 0.899 | 0.565 | 0.859650565826 | 1000 genomes | 1.99681E-04 | None | None | disulfide | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| C/Y | 7681 |
Ig-61 |
74 | rs573529663 |
0.9919 | -1.386 | 1.0 | D | 0.899 | 0.565 | 0.859650565826 | gnomAD-4.0.0 | 2.57784E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.83286E-06 | 0 | 0 |
| C/R | 7868 |
Ig-63 |
74 | rs1158489320 |
0.9984 | None | 1.0 | D | 0.906 | 0.696 | 0.818476300364 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| C/R | 7868 |
Ig-63 |
74 | rs1158489320 |
0.9984 | None | 1.0 | D | 0.906 | 0.696 | 0.818476300364 | gnomAD-4.0.0 | 4.33878E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23025E-05 | None | 0 | 0 | 5.0863E-06 | 0 | 0 |
| F/L | 7961 |
Ig-64 |
73 | None | 0.9652 | None | 0.035 | N | 0.447 | 0.184 | 0.107399877778 | gnomAD-4.0.0 | 6.84365E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99688E-06 | 0 | 0 |
| C/G | 8336 |
Ig-68 |
73 | None | 0.9071 | None | 0.999 | D | 0.855 | 0.767 | 0.925936472269 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/S | 8336 |
Ig-68 |
73 | None | 0.9785 | None | 1.0 | D | 0.745 | 0.767 | 0.862583160585 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/Y | 8432 |
Ig-69 |
73 | None | 0.978 | None | 1.0 | D | 0.901 | 0.602 | 0.782265642558 | gnomAD-4.0.0 | 6.84526E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99713E-07 | 0 | 0 |
| C/Y | 8528 |
Ig-70 |
73 | rs1364963458 |
0.9926 | -1.678 | 1.0 | D | 0.82 | 0.582 | 0.869667680407 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| C/Y | 8528 |
Ig-70 |
73 | rs1364963458 |
0.9926 | -1.678 | 1.0 | D | 0.82 | 0.582 | 0.869667680407 | gnomAD-4.0.0 | 4.10599E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39761E-06 | 0 | 0 |
| C/Y | 8622 |
Ig-71 |
74 | None | 0.9896 | None | 1.0 | D | 0.905 | 0.639 | 0.818437442364 | gnomAD-4.0.0 | 1.59168E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85932E-06 | 0 | 0 |
| C/F | 8715 |
Ig-72 |
73 | rs183499397 |
0.8777 | -1.599 | 1.0 | D | 0.893 | 0.669 | 0.85205978809 | gnomAD-2.1.1 | 2.82E-05 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.29238E-04 | None | 0 | 0 | 0 |
| C/F | 8715 |
Ig-72 |
73 | rs183499397 |
0.8777 | -1.599 | 1.0 | D | 0.893 | 0.669 | 0.85205978809 | gnomAD-3.1.2 | 1.31E-05 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.1425E-04 | 0 |
| C/F | 8715 |
Ig-72 |
73 | rs183499397 |
0.8777 | -1.599 | 1.0 | D | 0.893 | 0.669 | 0.85205978809 | gnomAD-4.0.0 | 2.10733E-05 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.5161E-04 | 3.20266E-05 |
| C/R | 8715 |
Ig-72 |
73 | rs2077266576 |
0.9949 | None | 1.0 | D | 0.905 | 0.753 | 0.867485530764 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/R | 8715 |
Ig-72 |
73 | rs2077266576 |
0.9949 | None | 1.0 | D | 0.905 | 0.753 | 0.867485530764 | gnomAD-4.0.0 | 3.84458E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.1814E-06 | 0 | 0 |
| C/Y | 8715 |
Ig-72 |
73 | rs183499397 |
0.9695 | -1.807 | 1.0 | D | 0.907 | 0.66 | None | gnomAD-2.1.1 | 6.79E-05 | None | None | disulfide | None | N | None | 1.65399E-04 | 0 | None | 0 | 7.68206E-04 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 8715 |
Ig-72 |
73 | rs183499397 |
0.9695 | -1.807 | 1.0 | D | 0.907 | 0.66 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | disulfide | None | N | None | 1.44788E-04 | 0 | 0 | 0 | 3.86847E-04 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 8715 |
Ig-72 |
73 | rs183499397 |
0.9695 | -1.807 | 1.0 | D | 0.907 | 0.66 | None | 1000 genomes | 1.99681E-04 | None | None | disulfide | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| C/Y | 8715 |
Ig-72 |
73 | rs183499397 |
0.9695 | -1.807 | 1.0 | D | 0.907 | 0.66 | None | gnomAD-4.0.0 | 1.92125E-05 | None | None | disulfide | None | N | None | 9.33259E-05 | 1.66633E-05 | None | 0 | 5.12775E-04 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 8809 |
Ig-73 |
74 | rs753253530 |
0.9787 | -1.014 | 1.0 | D | 0.901 | 0.768 | 0.816451128208 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| C/G | 8998 |
Ig-75 |
73 | rs992449953 |
0.8829 | None | 1.0 | D | 0.875 | 0.725 | 0.836894289642 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| C/W | 9091 |
Ig-76 |
73 | rs375546576 |
0.9741 | -1.542 | 1.0 | D | 0.884 | 0.566 | 0.797395815551 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
| C/W | 9091 |
Ig-76 |
73 | rs375546576 |
0.9741 | -1.542 | 1.0 | D | 0.884 | 0.566 | 0.797395815551 | gnomAD-4.0.0 | 6.84212E-07 | None | None | None | None | N | None | 2.98793E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 9184 |
Ig-77 |
73 | rs752178779 |
0.9013 | -1.449 | 1.0 | D | 0.915 | 0.715 | 0.824375450487 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
| C/Y | 9184 |
Ig-77 |
73 | rs752178779 |
0.9013 | -1.449 | 1.0 | D | 0.915 | 0.715 | 0.824375450487 | gnomAD-4.0.0 | 1.59128E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77269E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 9277 |
Ig-78 |
73 | None | 0.9795 | None | 1.0 | D | 0.8 | 0.733 | 0.787498767372 | gnomAD-4.0.0 | 7.20193E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| C/G | 9373 |
Ig-79 |
73 | rs758050033 |
0.9192 | -2.356 | 1.0 | None | 0.875 | 0.76 | 0.875584493258 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| C/G | 9373 |
Ig-79 |
73 | rs758050033 |
0.9192 | -2.356 | 1.0 | None | 0.875 | 0.76 | 0.875584493258 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/G | 9373 |
Ig-79 |
73 | rs758050033 |
0.9192 | -2.356 | 1.0 | None | 0.875 | 0.76 | 0.875584493258 | gnomAD-4.0.0 | 4.95756E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78104E-06 | 0 | 0 |
| C/R | 9373 |
Ig-79 |
73 | rs758050033 |
0.9957 | -0.729 | 1.0 | None | 0.905 | 0.781 | 0.870106137535 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| C/R | 9373 |
Ig-79 |
73 | rs758050033 |
0.9957 | -0.729 | 1.0 | None | 0.905 | 0.781 | 0.870106137535 | gnomAD-4.0.0 | 6.84244E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15966E-05 | 0 |
| C/R | 9566 |
Ig-81 |
74 | None | 0.9958 | None | 1.0 | None | 0.869 | 0.793 | 0.861489576853 | gnomAD-4.0.0 | 6.15772E-06 | None | None | None | None | N | None | 2.98721E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19563E-06 | 0 | 0 |
| C/S | 9566 |
Ig-81 |
74 | None | 0.898 | None | 1.0 | None | 0.71 | 0.746 | 0.771572928667 | gnomAD-4.0.0 | 6.84191E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| C/R | 9662 |
Ig-82 |
73 | None | 0.9975 | None | 1.0 | None | 0.903 | 0.856 | 0.883469295186 | gnomAD-4.0.0 | 1.59122E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85801E-06 | 0 | 0 |
| Y/H | 14036 |
Ig-90 |
72 | None | 0.9892 | None | 0.999 | N | 0.794 | 0.471 | 0.337868961071 | gnomAD-4.0.0 | 3.18513E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72164E-06 | 0 | 0 |
| A/S | 14124 |
Ig-91 |
71 | rs753046446 |
0.5253 | -1.332 | 0.959 | N | 0.678 | 0.297 | 0.216624796971 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| A/S | 14124 |
Ig-91 |
71 | rs753046446 |
0.5253 | -1.332 | 0.959 | N | 0.678 | 0.297 | 0.216624796971 | gnomAD-4.0.0 | 3.19122E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72426E-06 | 0 | 0 |
| A/S | 14213 |
Ig-92 |
72 | None | 0.5465 | None | 0.581 | D | 0.675 | 0.322 | 0.208816687407 | gnomAD-4.0.0 | 1.36875E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5208E-05 | None | 0 | 0 | 8.99611E-07 | 0 | 0 |
| A/T | 14213 |
Ig-92 |
72 | rs892930093 |
0.5745 | None | 0.41 | D | 0.749 | 0.334 | 0.212008924253 | gnomAD-4.0.0 | 1.36875E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5208E-05 | None | 0 | 0 | 8.99611E-07 | 0 | 0 |
| C/S | 14301 |
Ig-93 |
71 | None | 0.9431 | None | 1.0 | D | 0.821 | 0.695 | 0.803415754643 | gnomAD-4.0.0 | 1.36882E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79923E-06 | 0 | 0 |
| C/Y | 14301 |
Ig-93 |
71 | rs777838603 |
0.9792 | -1.548 | 1.0 | D | 0.891 | 0.558 | 0.819239731598 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| F/I | 14479 |
Ig-95 |
72 | rs1184251114 |
0.7201 | -1.513 | 1.0 | D | 0.792 | 0.537 | 0.615873902259 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| F/I | 14479 |
Ig-95 |
72 | rs1184251114 |
0.7201 | -1.513 | 1.0 | D | 0.792 | 0.537 | 0.615873902259 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/I | 14479 |
Ig-95 |
72 | rs1184251114 |
0.7201 | -1.513 | 1.0 | D | 0.792 | 0.537 | 0.615873902259 | gnomAD-4.0.0 | 4.339E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08661E-06 | 0 | 1.6019E-05 |
| F/Y | 14479 |
Ig-95 |
72 | rs2059938240 |
0.6621 | None | 0.999 | D | 0.649 | 0.516 | 0.73816917926 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/Y | 14479 |
Ig-95 |
72 | rs2059938240 |
0.6621 | None | 0.999 | D | 0.649 | 0.516 | 0.73816917926 | gnomAD-4.0.0 | 2.56366E-06 | None | None | None | None | N | None | 1.6921E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.34059E-05 | 0 |
| V/G | 14568 |
Ig-96 |
72 | None | 0.7009 | None | 0.935 | D | 0.835 | 0.736 | 0.94186883414 | gnomAD-4.0.0 | 1.60354E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8773E-06 | 0 | 0 |
| V/I | 14568 |
Ig-96 |
72 | rs372384272 |
0.1348 | 0.396 | 0.025 | D | 0.392 | 0.29 | None | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 6.83E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/I | 14568 |
Ig-96 |
72 | rs372384272 |
0.1348 | 0.396 | 0.025 | D | 0.392 | 0.29 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 14568 |
Ig-96 |
72 | rs372384272 |
0.1348 | 0.396 | 0.025 | D | 0.392 | 0.29 | None | gnomAD-4.0.0 | 4.97249E-06 | None | None | None | None | N | None | 1.06866E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/G | 14657 |
Ig-97 |
72 | rs772937665 |
0.8194 | -2.247 | 1.0 | D | 0.866 | 0.734 | 0.867611819263 | gnomAD-2.1.1 | 8.06E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 1.66279E-04 |
| C/G | 14657 |
Ig-97 |
72 | rs772937665 |
0.8194 | -2.247 | 1.0 | D | 0.866 | 0.734 | 0.867611819263 | gnomAD-4.0.0 | 1.57414E-05 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.06907E-05 | 0 | 0 |
| C/S | 14657 |
Ig-97 |
72 | rs774245300 |
0.9322 | -1.985 | 1.0 | D | 0.817 | 0.724 | 0.814495342469 | gnomAD-2.1.1 | 2.86E-05 | None | None | disulfide | None | N | None | 3.30633E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/S | 14657 |
Ig-97 |
72 | rs774245300 |
0.9322 | -1.985 | 1.0 | D | 0.817 | 0.724 | 0.814495342469 | gnomAD-3.1.2 | 5.92E-05 | None | None | disulfide | None | N | None | 2.1715E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 14657 |
Ig-97 |
72 | rs774245300 |
0.9322 | -1.985 | 1.0 | D | 0.817 | 0.724 | 0.814495342469 | gnomAD-4.0.0 | 8.6783E-06 | None | None | disulfide | None | N | None | 1.73569E-04 | 0 | None | 0 | 0 | None | 0 | 1.64582E-04 | 0 | 0 | 0 |
| C/Y | 14657 |
Ig-97 |
72 | rs774245300 |
0.9638 | None | 1.0 | D | 0.887 | 0.581 | 0.840231561563 | gnomAD-4.0.0 | 6.84402E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99593E-07 | 0 | 0 |
| L/I | 14835 |
Ig-99 |
71 | None | 0.1515 | None | 0.884 | N | 0.375 | 0.093 | 0.188950314367 | gnomAD-4.0.0 | 1.3741E-06 | None | None | None | None | N | None | 3.03306E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.66384E-05 |
| L/Q | 14835 |
Ig-99 |
71 | rs1559907686 |
0.9528 | None | 1.0 | N | 0.929 | 0.44 | 0.696656391576 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 1.26711E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 14924 |
Ig-100 |
72 | None | 0.9798 | None | 1.0 | D | 0.888 | 0.573 | 0.572071643794 | gnomAD-4.0.0 | 1.59369E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8631E-06 | 0 | 0 |
| C/R | 15013 |
Ig-101 |
72 | None | 0.9947 | None | 1.0 | D | 0.893 | 0.797 | 0.730682531328 | gnomAD-4.0.0 | 6.84851E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00027E-07 | 0 | 0 |
| C/S | 15013 |
Ig-101 |
72 | rs2058346797 |
0.9522 | None | 1.0 | D | 0.818 | 0.767 | 0.772288770895 | gnomAD-3.1.2 | 6.58E-06 | None | None | disulfide | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 15013 |
Ig-101 |
72 | rs2058346797 |
0.9522 | None | 1.0 | D | 0.818 | 0.767 | 0.772288770895 | gnomAD-4.0.0 | 1.86084E-06 | None | None | disulfide | None | N | None | 1.33651E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69631E-06 | 0 | 0 |
| C/Y | 15102 |
Ig-102 |
72 | None | 0.9882 | None | 1.0 | D | 0.901 | 0.636 | 0.912014209022 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/L | 15191 |
Ig-103 |
72 | None | 0.5488 | None | 0.64 | N | 0.666 | 0.129 | 0.543691374674 | gnomAD-4.0.0 | 1.59369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02828E-05 |
| V/L | 15279 |
Ig-104 |
72 | None | 0.3661 | None | 0.437 | N | 0.48 | 0.166 | 0.380052290102 | gnomAD-4.0.0 | 6.84593E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15982E-05 | 0 |
| V/M | 15279 |
Ig-104 |
72 | rs727504197 |
0.3973 | -0.43 | 0.968 | D | 0.701 | 0.273 | 0.509820907775 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 5.66E-05 | None | 0 | 0 | None | 0 | None | 0 | 7.85E-06 | 0 |
| V/M | 15279 |
Ig-104 |
72 | rs727504197 |
0.3973 | -0.43 | 0.968 | D | 0.701 | 0.273 | 0.509820907775 | gnomAD-4.0.0 | 5.47674E-06 | None | None | None | None | N | None | 0 | 1.34264E-04 | None | 0 | 0 | None | 0 | 0 | 1.79983E-06 | 0 | 0 |
| V/D | 15373 |
Ig-105 |
72 | rs2058089139 |
0.9956 | None | 0.998 | D | 0.853 | 0.483 | 0.75824790645 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/D | 15373 |
Ig-105 |
72 | rs2058089139 |
0.9956 | None | 0.998 | D | 0.853 | 0.483 | 0.75824790645 | gnomAD-4.0.0 | 6.58302E-06 | None | None | None | None | N | None | 0 | 6.56858E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/W | 15462 |
Ig-106 |
72 | None | 0.9914 | None | 1.0 | D | 0.864 | 0.821 | 0.859364730717 | gnomAD-4.0.0 | 6.84994E-07 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0019E-07 | 0 | 0 |
| F/L | 15551 |
Ig-107 |
72 | None | 0.9318 | None | 0.015 | N | 0.37 | 0.344 | 0.411665641125 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/Y | 15551 |
Ig-107 |
72 | rs1329504399 |
0.6991 | -1.403 | 0.986 | D | 0.619 | 0.521 | 0.652270480338 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| F/Y | 15551 |
Ig-107 |
72 | rs1329504399 |
0.6991 | -1.403 | 0.986 | D | 0.619 | 0.521 | 0.652270480338 | gnomAD-4.0.0 | 1.59486E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86503E-06 | 0 | 0 |
| I/L | 15637 |
Ig-108 |
70 | rs1029825916 |
0.1817 | None | 0.025 | N | 0.408 | 0.063 | 0.158396225186 | gnomAD-4.0.0 | 2.73894E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79993E-06 | 0 | 3.31774E-05 |
| I/T | 15637 |
Ig-108 |
70 | None | 0.6254 | None | 0.124 | N | 0.715 | 0.255 | 0.515659482774 | gnomAD-4.0.0 | 1.59407E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86325E-06 | 0 | 0 |
| I/V | 15637 |
Ig-108 |
70 | None | 0.0656 | None | None | N | 0.329 | 0.053 | 0.107399877778 | gnomAD-4.0.0 | 1.36947E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79993E-06 | 0 | 0 |
| L/V | 16035 |
Ig-109 |
68 | rs371209083 |
0.1512 | -0.804 | 0.898 | N | 0.705 | 0.148 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| L/V | 16035 |
Ig-109 |
68 | rs371209083 |
0.1512 | -0.804 | 0.898 | N | 0.705 | 0.148 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| L/V | 16035 |
Ig-109 |
68 | rs371209083 |
0.1512 | -0.804 | 0.898 | N | 0.705 | 0.148 | None | gnomAD-4.0.0 | 5.13148E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.58589E-06 | 0 | 0 |
| I/T | 16331 |
Ig-110 |
70 | None | 0.9317 | None | 0.939 | D | 0.735 | 0.426 | 0.629781192331 | gnomAD-4.0.0 | 2.73913E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59963E-06 | 0 | 0 |
| I/F | 17027 |
Ig-111 |
73 | rs770809063 |
0.5164 | -1.786 | 0.001 | N | 0.423 | 0.217 | 0.197625483188 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| I/F | 17027 |
Ig-111 |
73 | rs770809063 |
0.5164 | -1.786 | 0.001 | N | 0.423 | 0.217 | 0.197625483188 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.42E-05 | 0 | 0 |
| I/F | 17027 |
Ig-111 |
73 | rs770809063 |
0.5164 | -1.786 | 0.001 | N | 0.423 | 0.217 | 0.197625483188 | gnomAD-4.0.0 | 6.41386E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.19832E-05 | 0 | 0 |
| I/M | 17349 |
Ig-112 |
99 | rs1273982598 |
0.2997 | -1.769 | 0.998 | N | 0.651 | 0.234 | 0.530509239904 | gnomAD-2.1.1 | 5.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 5.46E-05 | None | 0 | 0 | 0 |
| I/M | 17349 |
Ig-112 |
99 | rs1273982598 |
0.2997 | -1.769 | 0.998 | N | 0.651 | 0.234 | 0.530509239904 | gnomAD-4.0.0 | 1.76556E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.75199E-05 | 0 |
| I/S | 18459 |
Ig-115 |
78 | None | 0.987 | None | 1.0 | N | 0.875 | 0.562 | 0.733087090833 | gnomAD-4.0.0 | 3.19958E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.7326E-06 | 0 | 0 |
| I/N | 18764 |
Ig-116 |
77 | None | 0.9885 | None | 0.912 | N | 0.83 | 0.475 | 0.751848519796 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 18764 |
Ig-116 |
77 | None | 0.0963 | None | 0.041 | N | 0.43 | 0.075 | 0.243398259712 | gnomAD-4.0.0 | 1.60411E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88893E-05 | 0 | 0 | 0 | 0 |
| V/E | 19459 |
Ig-118 |
69 | None | 0.9923 | None | 0.998 | N | 0.862 | 0.537 | 0.776716716212 | gnomAD-4.0.0 | 1.5917E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| L/S | 19857 |
Ig-119 |
68 | rs547180437 |
0.9965 | -2.984 | 1.0 | N | 0.917 | 0.551 | 0.758188736314 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93798E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/S | 19857 |
Ig-119 |
68 | rs547180437 |
0.9965 | -2.984 | 1.0 | N | 0.917 | 0.551 | 0.758188736314 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| L/S | 19857 |
Ig-119 |
68 | rs547180437 |
0.9965 | -2.984 | 1.0 | N | 0.917 | 0.551 | 0.758188736314 | gnomAD-4.0.0 | 1.54942E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.46608E-05 | None | 0 | 0 | 1.86503E-05 | 0 | 1.60077E-05 |
| I/T | 20151 |
Ig-120 |
72 | rs746925706 |
0.9612 | -2.288 | 0.117 | N | 0.683 | 0.295 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 20151 |
Ig-120 |
72 | rs746925706 |
0.9612 | -2.288 | 0.117 | N | 0.683 | 0.295 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 20151 |
Ig-120 |
72 | rs746925706 |
0.9612 | -2.288 | 0.117 | N | 0.683 | 0.295 | None | gnomAD-4.0.0 | 6.57765E-06 | None | None | None | None | N | None | 2.41406E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/F | 20549 |
Ig-121 |
71 | rs750680415 |
0.7088 | None | 0.989 | N | 0.749 | 0.298 | 0.523133305157 | gnomAD-4.0.0 | 1.36896E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79946E-06 | 0 | 0 |
| I/M | 20549 |
Ig-121 |
71 | None | 0.4831 | None | 0.989 | N | 0.705 | 0.288 | 0.470072546239 | gnomAD-4.0.0 | 6.8445E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99683E-07 | 0 | 0 |
| I/T | 20549 |
Ig-121 |
71 | None | 0.9743 | None | 0.98 | N | 0.717 | 0.408 | 0.611003947198 | gnomAD-4.0.0 | 1.36889E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99674E-07 | 0 | 1.65717E-05 |
| I/V | 20549 |
Ig-121 |
71 | rs750680415 |
0.1429 | -1.333 | 0.689 | N | 0.399 | 0.117 | 0.371903410333 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 1.29216E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 20549 |
Ig-121 |
71 | rs750680415 |
0.1429 | -1.333 | 0.689 | N | 0.399 | 0.117 | 0.371903410333 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 20549 |
Ig-121 |
71 | rs750680415 |
0.1429 | -1.333 | 0.689 | N | 0.399 | 0.117 | 0.371903410333 | gnomAD-4.0.0 | 1.85984E-06 | None | None | None | None | N | None | 4.00588E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 20844 |
Ig-122 |
76 | rs775731244 |
0.8227 | -2.275 | 0.104 | N | 0.693 | 0.263 | 0.386882687439 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| V/A | 20844 |
Ig-122 |
76 | rs775731244 |
0.8227 | -2.275 | 0.104 | N | 0.693 | 0.263 | 0.386882687439 | gnomAD-4.0.0 | 2.73721E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.63768E-05 | 0 |
| L/F | 21246 |
Ig-123 |
70 | rs2049306666 |
0.6834 | None | 1.0 | N | 0.859 | 0.375 | 0.562428738172 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 21246 |
Ig-123 |
70 | rs2049306666 |
0.6834 | None | 1.0 | N | 0.859 | 0.375 | 0.562428738172 | gnomAD-4.0.0 | 6.57903E-06 | None | None | None | None | N | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 21246 |
Ig-123 |
70 | None | 0.2221 | None | 0.999 | N | 0.713 | 0.193 | 0.418964662724 | gnomAD-4.0.0 | 1.59435E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86208E-06 | 0 | 0 |
| L/F | 21539 |
Ig-124 |
71 | rs1060500431 |
0.6394 | None | 1.0 | N | 0.843 | 0.399 | 0.557597400255 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/F | 21539 |
Ig-124 |
71 | rs1060500431 |
0.6394 | None | 1.0 | N | 0.843 | 0.399 | 0.557597400255 | gnomAD-4.0.0 | 2.56433E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.79069E-06 | 0 | 0 |
| I/V | 21936 |
Ig-125 |
71 | None | 0.0952 | None | 0.02 | N | 0.296 | 0.096 | 0.298056030225 | gnomAD-4.0.0 | 1.70071E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.05254E-06 | 0 | 0 |
| L/S | 22334 |
Ig-126 |
70 | rs758106978 |
0.9949 | -3.128 | 1.0 | N | 0.888 | 0.539 | 0.761447629884 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.59823E-04 | None | 0 | None | 0 | 0 | 0 |
| L/S | 22334 |
Ig-126 |
70 | rs758106978 |
0.9949 | -3.128 | 1.0 | N | 0.888 | 0.539 | 0.761447629884 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/S | 22334 |
Ig-126 |
70 | rs758106978 |
0.9949 | -3.128 | 1.0 | N | 0.888 | 0.539 | 0.761447629884 | gnomAD-4.0.0 | 3.71944E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.33887E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 22334 |
Ig-126 |
70 | rs766103894 |
0.2155 | -1.142 | 0.999 | N | 0.773 | 0.247 | 0.308904156042 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| L/V | 22334 |
Ig-126 |
70 | rs766103894 |
0.2155 | -1.142 | 0.999 | N | 0.773 | 0.247 | 0.308904156042 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/V | 22334 |
Ig-126 |
70 | rs766103894 |
0.2155 | -1.142 | 0.999 | N | 0.773 | 0.247 | 0.308904156042 | gnomAD-4.0.0 | 4.3393E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93494E-06 | 0 | 0 |
| I/N | 22623 |
Ig-127 |
64 | rs765139811 |
0.9943 | -2.287 | 0.999 | N | 0.848 | 0.594 | 0.772838041564 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/N | 22623 |
Ig-127 |
64 | rs765139811 |
0.9943 | -2.287 | 0.999 | N | 0.848 | 0.594 | 0.772838041564 | gnomAD-4.0.0 | 6.84343E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15942E-05 | 0 |
| I/S | 22623 |
Ig-127 |
64 | None | 0.9904 | None | 0.998 | N | 0.824 | 0.549 | 0.70627472995 | gnomAD-4.0.0 | 6.84343E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52309E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 22623 |
Ig-127 |
64 | None | 0.9788 | None | 0.989 | N | 0.79 | 0.481 | 0.607307720492 | gnomAD-4.0.0 | 2.73737E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59847E-06 | 0 | 0 |
| I/L | 23020 |
Ig-128 |
71 | None | 0.1952 | None | 0.011 | N | 0.353 | 0.144 | 0.357929162469 | gnomAD-4.0.0 | 1.59241E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.027E-05 |
| I/N | 23020 |
Ig-128 |
71 | None | 0.9898 | None | 0.994 | N | 0.861 | 0.573 | 0.729413103106 | gnomAD-4.0.0 | 1.36884E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79925E-06 | 0 | 0 |
| I/S | 23020 |
Ig-128 |
71 | None | 0.9876 | None | 0.983 | N | 0.811 | 0.56 | 0.74021432234 | gnomAD-4.0.0 | 6.84419E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15953E-05 | 0 |
| M/L | 23415 |
Ig-129 |
71 | rs200029470 |
0.1407 | -0.621 | 0.002 | N | 0.305 | 0.177 | 0.27479166964 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| M/L | 23415 |
Ig-129 |
71 | rs200029470 |
0.1407 | -0.621 | 0.002 | N | 0.305 | 0.177 | 0.27479166964 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| M/L | 23415 |
Ig-129 |
71 | rs200029470 |
0.1407 | -0.621 | 0.002 | N | 0.305 | 0.177 | 0.27479166964 | gnomAD-4.0.0 | 1.05354E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.44115E-05 | 0 | 0 |
| M/T | 23415 |
Ig-129 |
71 | rs765861604 |
0.9334 | -1.67 | 0.912 | N | 0.628 | 0.372 | 0.637519714765 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| M/T | 23415 |
Ig-129 |
71 | rs765861604 |
0.9334 | -1.67 | 0.912 | N | 0.628 | 0.372 | 0.637519714765 | gnomAD-4.0.0 | 4.7749E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.5779E-06 | 0 | 0 |
| L/I | 23706 |
Ig-130 |
70 | rs760319001 |
0.0823 | -0.734 | 0.016 | N | 0.409 | 0.052 | 0.107399877778 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.96181E-04 | None | 0 | 0 | 0 |
| L/I | 23706 |
Ig-130 |
70 | rs760319001 |
0.0823 | -0.734 | 0.016 | N | 0.409 | 0.052 | 0.107399877778 | gnomAD-4.0.0 | 8.89672E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.50739E-04 | 0 |
| L/S | 23706 |
Ig-130 |
70 | rs1481919740 |
0.9652 | -3.466 | 0.81 | N | 0.79 | 0.424 | 0.700159432204 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| L/S | 23706 |
Ig-130 |
70 | rs1481919740 |
0.9652 | -3.466 | 0.81 | N | 0.79 | 0.424 | 0.700159432204 | gnomAD-4.0.0 | 1.59209E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| L/R | 24102 |
Ig-131 |
74 | None | 0.9915 | None | 0.997 | N | 0.891 | 0.602 | 0.766578170383 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 24102 |
Ig-131 |
74 | rs780348282 |
0.1329 | -1.198 | 0.117 | N | 0.416 | 0.132 | 0.380394304726 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| L/V | 24102 |
Ig-131 |
74 | rs780348282 |
0.1329 | -1.198 | 0.117 | N | 0.416 | 0.132 | 0.380394304726 | gnomAD-4.0.0 | 1.37012E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.32428E-05 | 0 |
| L/P | 24499 |
Ig-132 |
69 | rs769255289 |
0.9987 | None | 0.994 | N | 0.825 | 0.599 | 0.776129731606 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 25184 |
Ig-134 |
74 | None | 0.118 | None | 0.618 | N | 0.708 | 0.103 | 0.128392430309 | gnomAD-4.0.0 | 6.84375E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52678E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 25870 |
Ig-136 |
73 | rs767544449 |
0.1488 | -0.83 | 0.426 | N | 0.411 | 0.127 | 0.424313518543 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| I/T | 25870 |
Ig-136 |
73 | rs754843336 |
0.9661 | -2.836 | 0.892 | N | 0.749 | 0.394 | 0.660037784989 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| I/T | 25870 |
Ig-136 |
73 | rs754843336 |
0.9661 | -2.836 | 0.892 | N | 0.749 | 0.394 | 0.660037784989 | gnomAD-4.0.0 | 3.42176E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49813E-06 | 0 | 0 |
| L/F | 26663 |
Ig-138 |
70 | None | 0.7607 | None | 1.0 | N | 0.837 | 0.299 | 0.468253365638 | gnomAD-4.0.0 | 5.47419E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29675E-06 | 0 | 1.65695E-05 |
| V/I | 26952 |
Ig-139 |
73 | rs371362606 |
0.0687 | -0.228 | 0.001 | N | 0.33 | 0.015 | None | gnomAD-2.1.1 | 7.15E-05 | None | None | None | None | N | None | 2.48098E-04 | 8.49E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 7.06E-05 | 1.40528E-04 |
| V/I | 26952 |
Ig-139 |
73 | rs371362606 |
0.0687 | -0.228 | 0.001 | N | 0.33 | 0.015 | None | gnomAD-3.1.2 | 1.05212E-04 | None | None | None | None | N | None | 1.93115E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.17644E-04 | 0 | 0 |
| V/I | 26952 |
Ig-139 |
73 | rs371362606 |
0.0687 | -0.228 | 0.001 | N | 0.33 | 0.015 | None | gnomAD-4.0.0 | 6.94099E-05 | None | None | None | None | N | None | 2.93302E-04 | 5.00133E-05 | None | 0 | 0 | None | 0 | 0 | 6.95112E-05 | 1.09803E-05 | 6.40348E-05 |
| V/L | 26952 |
Ig-139 |
73 | rs371362606 |
0.1857 | -0.23 | None | N | 0.357 | 0.053 | 0.0482279557977 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| V/L | 26952 |
Ig-139 |
73 | rs371362606 |
0.1857 | -0.23 | None | N | 0.357 | 0.053 | 0.0482279557977 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| V/L | 26952 |
Ig-139 |
73 | rs371362606 |
0.1857 | -0.23 | None | N | 0.357 | 0.053 | 0.0482279557977 | gnomAD-4.0.0 | 1.92131E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54307E-05 | 0 | 1.60143E-05 |
| L/V | 27746 |
Ig-141 |
71 | rs1018294368 |
0.191 | -1.156 | 0.767 | N | 0.401 | 0.128 | 0.300784259202 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| L/V | 27746 |
Ig-141 |
71 | rs1018294368 |
0.191 | -1.156 | 0.767 | N | 0.401 | 0.128 | 0.300784259202 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/V | 27746 |
Ig-141 |
71 | rs1018294368 |
0.191 | -1.156 | 0.767 | N | 0.401 | 0.128 | 0.300784259202 | gnomAD-4.0.0 | 6.57479E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47033E-05 | 0 | 0 |
| L/F | 28035 |
Ig-142 |
73 | rs878854394 |
0.5211 | -1.806 | 0.901 | N | 0.745 | 0.147 | 0.298403945805 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| L/F | 28035 |
Ig-142 |
73 | rs878854394 |
0.5211 | -1.806 | 0.901 | N | 0.745 | 0.147 | 0.298403945805 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/F | 28035 |
Ig-142 |
73 | rs878854394 |
0.5211 | -1.806 | 0.901 | N | 0.745 | 0.147 | 0.298403945805 | gnomAD-4.0.0 | 4.95861E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78136E-06 | 0 | 0 |
| L/F | 28825 |
Ig-144 |
71 | None | 0.6902 | None | 0.994 | N | 0.689 | 0.319 | 0.492816438443 | gnomAD-4.0.0 | 1.59261E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43583E-05 | 0 |
| L/I | 28825 |
Ig-144 |
71 | rs1575605256 |
0.0891 | None | 0.248 | N | 0.387 | 0.05 | 0.171388866994 | gnomAD-4.0.0 | 1.59269E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43579E-05 | 0 |
| L/S | 29513 |
Ig-146 |
70 | rs1318031463 |
0.9962 | -2.76 | 0.999 | N | 0.844 | 0.521 | 0.674404827817 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| L/S | 29513 |
Ig-146 |
70 | rs1318031463 |
0.9962 | -2.76 | 0.999 | N | 0.844 | 0.521 | 0.674404827817 | gnomAD-4.0.0 | 1.59133E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85785E-06 | 0 | 0 |
| L/F | 29912 |
Ig-147 |
71 | None | 0.5418 | None | 0.942 | N | 0.714 | 0.26 | 0.389904358541 | gnomAD-4.0.0 | 1.59168E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| L/P | 29912 |
Ig-147 |
71 | rs748326514 |
0.9962 | -1.683 | 0.99 | N | 0.874 | 0.65 | 0.804452295794 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 1.15996E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 1.65893E-04 |
| L/P | 29912 |
Ig-147 |
71 | rs748326514 |
0.9962 | -1.683 | 0.99 | N | 0.874 | 0.65 | 0.804452295794 | gnomAD-4.0.0 | 9.58034E-06 | None | None | None | None | N | None | 0 | 4.47207E-05 | None | 0 | 0 | None | 0 | 0 | 8.09648E-06 | 0 | 4.97001E-05 |
| V/A | 30204 |
Ig-148 |
73 | rs1699759872 |
0.5883 | None | 0.052 | N | 0.585 | 0.239 | 0.469415673434 | gnomAD-4.0.0 | 6.84399E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99588E-07 | 0 | 0 |
| V/I | 30204 |
Ig-148 |
73 | rs898701169 |
0.0682 | None | None | N | 0.274 | 0.052 | 0.0954503805726 | gnomAD-4.0.0 | 6.84415E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16139E-05 | 0 |
| L/F | 30996 |
Ig-150 |
70 | rs1698155054 |
0.1257 | None | 0.002 | N | 0.419 | 0.152 | 0.322510055762 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/P | 30996 |
Ig-150 |
70 | rs751341499 |
0.9949 | -1.267 | 0.916 | N | 0.853 | 0.62 | None | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| L/P | 30996 |
Ig-150 |
70 | rs751341499 |
0.9949 | -1.267 | 0.916 | N | 0.853 | 0.62 | None | gnomAD-4.0.0 | 5.47345E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39668E-06 | 0 | 3.31312E-05 |
| L/S | 31688 |
Ig-152 |
68 | rs794729538 |
0.9971 | None | 1.0 | N | 0.864 | 0.552 | 0.767629022357 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| I/L | 32085 |
Ig-153 |
69 | rs761147994 |
0.1576 | -0.768 | 0.889 | N | 0.443 | 0.178 | 0.264081493735 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| I/L | 32085 |
Ig-153 |
69 | rs761147994 |
0.1576 | -0.768 | 0.889 | N | 0.443 | 0.178 | 0.264081493735 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 32085 |
Ig-153 |
69 | rs761147994 |
0.1576 | -0.768 | 0.889 | N | 0.443 | 0.178 | 0.264081493735 | gnomAD-4.0.0 | 1.05353E-05 | None | None | None | None | N | None | 1.3354E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35624E-05 | 0 | 0 |
| I/T | 32085 |
Ig-153 |
69 | None | 0.7456 | None | 0.989 | N | 0.739 | 0.412 | 0.561027722634 | gnomAD-4.0.0 | 1.59147E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85878E-06 | 0 | 0 |
| L/F | 32379 |
Ig-154 |
73 | rs1361697291 |
0.6195 | -1.724 | 1.0 | N | 0.841 | 0.387 | 0.406945738958 | gnomAD-2.1.1 | 6.37E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.29634E-04 | 0 |
| L/F | 32379 |
Ig-154 |
73 | rs1361697291 |
0.6195 | -1.724 | 1.0 | N | 0.841 | 0.387 | 0.406945738958 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/F | 32379 |
Ig-154 |
73 | rs1361697291 |
0.6195 | -1.724 | 1.0 | N | 0.841 | 0.387 | 0.406945738958 | gnomAD-4.0.0 | 6.08986E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.2296E-06 | 0 | 0 |
| L/M | 32775 |
Ig-155 |
68 | None | 0.2751 | None | 1.0 | N | 0.815 | 0.259 | 0.315903272564 | gnomAD-4.0.0 | 6.84202E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.6564E-05 |
| C/S | 33173 |
Ig-156 |
73 | rs773021609 |
0.9644 | -2.168 | 1.0 | D | 0.779 | 0.783 | 0.746301299509 | gnomAD-2.1.1 | 4.02E-06 | None | None | disulfide | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/S | 33173 |
Ig-156 |
73 | rs773021609 |
0.9644 | -2.168 | 1.0 | D | 0.779 | 0.783 | 0.746301299509 | gnomAD-3.1.2 | 5.26E-05 | None | None | disulfide | None | N | None | 1.20616E-04 | 1.96618E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 33173 |
Ig-156 |
73 | rs773021609 |
0.9644 | -2.168 | 1.0 | D | 0.779 | 0.783 | 0.746301299509 | gnomAD-4.0.0 | 1.92162E-05 | None | None | disulfide | None | N | None | 1.01475E-04 | 8.47745E-05 | None | 0 | 0 | None | 0 | 0 | 2.39296E-06 | 0 | 8.53388E-05 |
| C/Y | 33173 |
Ig-156 |
73 | rs761362832 |
0.9859 | -1.68 | 1.0 | D | 0.883 | 0.755 | 0.770587509068 | gnomAD-2.1.1 | 5.22E-05 | None | None | disulfide | None | N | None | 0 | 3.19174E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 1.65673E-04 |
| C/Y | 33173 |
Ig-156 |
73 | rs761362832 |
0.9859 | -1.68 | 1.0 | D | 0.883 | 0.755 | 0.770587509068 | gnomAD-3.1.2 | 2.63E-05 | None | None | disulfide | None | N | None | 0 | 1.96618E-04 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 33173 |
Ig-156 |
73 | rs761362832 |
0.9859 | -1.68 | 1.0 | D | 0.883 | 0.755 | 0.770587509068 | gnomAD-4.0.0 | 2.72678E-05 | None | None | disulfide | None | N | None | 0 | 3.5021E-04 | None | 0 | 0 | None | 0 | 0 | 1.78001E-05 | 0 | 3.20266E-05 |
| V/F | 33570 |
Ig-158 |
75 | rs1208247404 |
0.8744 | None | 0.059 | D | 0.601 | 0.594 | 0.72348304321 | gnomAD-4.0.0 | 1.66186E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.99045E-06 | 0 | 0 |
| V/I | 33669 |
Ig-159 |
74 | rs1331642312 |
0.1322 | None | 0.662 | N | 0.338 | 0.126 | 0.452640719197 | gnomAD-4.0.0 | 3.42106E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49732E-06 | 0 | 0 |
| C/R | 34209 |
Ig-160 |
73 | None | 0.9983 | None | 1.0 | D | 0.9 | 0.731 | 0.80271299889 | gnomAD-4.0.0 | 1.20032E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/A | 34333 |
Ig-161 |
76 | None | 0.6227 | None | 0.822 | N | 0.697 | 0.329 | 0.470566500458 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/I | 34333 |
Ig-161 |
76 | rs763815899 |
0.0851 | 0.241 | 0.014 | N | 0.319 | 0.032 | 0.126345400529 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| V/I | 34333 |
Ig-161 |
76 | rs763815899 |
0.0851 | 0.241 | 0.014 | N | 0.319 | 0.032 | 0.126345400529 | gnomAD-4.0.0 | 3.182E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77269E-05 | None | 0 | 0 | 2.85768E-06 | 0 | 0 |
| V/L | 34333 |
Ig-161 |
76 | rs763815899 |
0.5497 | 0.238 | 0.247 | N | 0.554 | 0.123 | 0.239305524855 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| V/L | 34333 |
Ig-161 |
76 | rs763815899 |
0.5497 | 0.238 | 0.247 | N | 0.554 | 0.123 | 0.239305524855 | gnomAD-4.0.0 | 1.591E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85768E-06 | 0 | 0 |
| V/A | 34436 |
Ig-162 |
74 | rs1575262566 |
0.9258 | None | 0.999 | N | 0.751 | 0.642 | 0.710200110468 | gnomAD-4.0.0 | 1.59101E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85765E-06 | 0 | 0 |
| V/I | 34436 |
Ig-162 |
74 | rs770266280 |
0.1882 | 0.035 | 0.997 | N | 0.609 | 0.327 | 0.72447223621 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| V/I | 34436 |
Ig-162 |
74 | rs770266280 |
0.1882 | 0.035 | 0.997 | N | 0.609 | 0.327 | 0.72447223621 | gnomAD-4.0.0 | 1.59105E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85768E-06 | 0 | 0 |
| A/D | 35014 |
Ig-163 |
73 | rs758356886 |
0.9972 | -2.575 | 0.995 | N | 0.801 | 0.287 | 0.485634191555 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 1.99872E-04 | 1.56E-05 | 0 |
| A/D | 35014 |
Ig-163 |
73 | rs758356886 |
0.9972 | -2.575 | 0.995 | N | 0.801 | 0.287 | 0.485634191555 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.42E-05 | 0 | 0 | 0 | 0 |
| A/D | 35014 |
Ig-163 |
73 | rs758356886 |
0.9972 | -2.575 | 0.995 | N | 0.801 | 0.287 | 0.485634191555 | gnomAD-4.0.0 | 1.11533E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.5623E-04 | 0 | 2.5426E-06 | 0 | 8.00487E-05 |
| V/A | 35201 |
Ig-164 |
73 | None | 0.5946 | None | 0.997 | N | 0.725 | 0.414 | 0.523031302909 | gnomAD-4.0.0 | 6.84141E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.7337E-04 | 0 | 0 | 0 |
| V/E | 35201 |
Ig-164 |
73 | rs1411169716 |
0.9884 | -2.987 | 0.999 | N | 0.884 | 0.653 | 0.632219009948 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| V/E | 35201 |
Ig-164 |
73 | rs1411169716 |
0.9884 | -2.987 | 0.999 | N | 0.884 | 0.653 | 0.632219009948 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/E | 35201 |
Ig-164 |
73 | rs1411169716 |
0.9884 | -2.987 | 0.999 | N | 0.884 | 0.653 | 0.632219009948 | gnomAD-4.0.0 | 1.23942E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69515E-06 | 0 | 0 |
| V/M | 35201 |
Ig-164 |
73 | rs397517797 |
0.4035 | -0.864 | 1.0 | N | 0.76 | 0.342 | 0.528308644755 | gnomAD-2.1.1 | 6.42E-05 | None | None | None | None | N | None | 0 | 3.18582E-04 | None | 0 | 1.11259E-04 | None | 6.54E-05 | None | 0 | 8.86E-06 | 0 |
| V/M | 35201 |
Ig-164 |
73 | rs397517797 |
0.4035 | -0.864 | 1.0 | N | 0.76 | 0.342 | 0.528308644755 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 35201 |
Ig-164 |
73 | rs397517797 |
0.4035 | -0.864 | 1.0 | N | 0.76 | 0.342 | 0.528308644755 | gnomAD-4.0.0 | 2.10683E-05 | None | None | None | None | N | None | 1.33504E-05 | 1.83358E-04 | None | 0 | 2.22777E-05 | None | 0 | 0 | 1.01704E-05 | 8.78291E-05 | 1.60087E-05 |
| C/R | 35359 |
Ig-165 |
74 | rs1414538562 |
0.9915 | -0.892 | 1.0 | D | 0.933 | 0.706 | 0.862525014085 | gnomAD-2.1.1 | 3.18E-05 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| C/R | 35359 |
Ig-165 |
74 | rs1414538562 |
0.9915 | -0.892 | 1.0 | D | 0.933 | 0.706 | 0.862525014085 | gnomAD-3.1.2 | 6.57E-06 | None | None | disulfide | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/R | 35359 |
Ig-165 |
74 | rs1414538562 |
0.9915 | -0.892 | 1.0 | D | 0.933 | 0.706 | 0.862525014085 | gnomAD-4.0.0 | 2.47847E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39012E-06 | 0 | 0 |
| C/W | 35359 |
Ig-165 |
74 | None | 0.9747 | None | 1.0 | D | 0.893 | 0.621 | 0.784202280294 | gnomAD-4.0.0 | 1.20037E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31256E-06 | 0 | 0 |
| C/Y | 35359 |
Ig-165 |
74 | None | 0.9623 | None | 1.0 | D | 0.926 | 0.771 | 0.811517266189 | gnomAD-4.0.0 | 1.59092E-06 | None | None | disulfide | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| C/G | 35492 |
Ig-166 |
73 | None | 0.6228 | None | 0.322 | D | 0.823 | 0.435 | 0.782552742157 | gnomAD-4.0.0 | 6.86708E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00383E-07 | 0 | 0 |
| C/R | 35492 |
Ig-166 |
73 | None | 0.9816 | None | 0.001 | D | 0.726 | 0.423 | 0.723900465636 | gnomAD-4.0.0 | 4.12025E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.4023E-06 | 0 | 0 |
| C/S | 35492 |
Ig-166 |
73 | rs1242910392 |
0.857 | -1.168 | 0.322 | D | 0.728 | 0.412 | 0.71166902715 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| C/S | 35492 |
Ig-166 |
73 | rs1242910392 |
0.857 | -1.168 | 0.322 | D | 0.728 | 0.412 | 0.71166902715 | gnomAD-4.0.0 | 6.86774E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00419E-07 | 0 | 0 |
| C/Y | 35492 |
Ig-166 |
73 | None | 0.7953 | None | 0.911 | D | 0.838 | 0.419 | 0.772592770513 | gnomAD-4.0.0 | 6.86774E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52781E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 35677 |
Ig-167 |
71 | None | 0.9869 | None | 0.997 | N | 0.862 | 0.591 | 0.801889373885 | gnomAD-4.0.0 | 3.42172E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49788E-06 | 0 | 0 |
| I/V | 35774 |
Ig-168 |
73 | rs774401824 |
0.0697 | -1.068 | None | N | 0.326 | 0.113 | 0.132336055621 | gnomAD-2.1.1 | 4.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56545E-04 | None | 0 | None | 0 | 0 | 0 |
| I/V | 35774 |
Ig-168 |
73 | rs774401824 |
0.0697 | -1.068 | None | N | 0.326 | 0.113 | 0.132336055621 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9216E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 35774 |
Ig-168 |
73 | rs774401824 |
0.0697 | -1.068 | None | N | 0.326 | 0.113 | 0.132336055621 | gnomAD-4.0.0 | 6.19629E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.00463E-04 | None | 0 | 0 | 8.47548E-07 | 0 | 0 |
| L/V | 35971 |
Ig-169 |
75 | None | 0.1825 | None | 0.999 | N | 0.709 | 0.302 | 0.430239905395 | gnomAD-4.0.0 | 1.59109E-06 | None | None | None | -1.257(OBSL1) -1.035(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85765E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.