Structural position:
- Domain Type: Ig
- Aligned Position: 159
- Secondary Structure Element: e
- Secondary Structure Region: β-strand F
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T/A | 179 |
Ig-2 |
76 | rs1453734474 |
0.1439 | -0.743 | 0.053 | N | 0.197 | 0.281 | 0.197625483188 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | 0.136(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/A | 179 |
Ig-2 |
76 | rs1453734474 |
0.1439 | -0.743 | 0.053 | N | 0.197 | 0.281 | 0.197625483188 | gnomAD-4.0.0 | 2.73623E-06 | None | None | None | 0.136(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.63725E-05 | 0 |
| V/A | 1018 |
Ig-3 |
76 | rs878967057 |
0.1937 | None | 0.001 | N | 0.089 | 0.149 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/A | 1018 |
Ig-3 |
76 | rs878967057 |
0.1937 | None | 0.001 | N | 0.089 | 0.149 | None | gnomAD-4.0.0 | 6.56927E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46977E-05 | 0 | 0 |
| R/C | 1159 |
Ig-4 |
78 | rs797046063 |
0.6319 | -0.447 | 1.0 | N | 0.745 | 0.556 | 0.7175160923 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | I | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| R/C | 1159 |
Ig-4 |
78 | rs797046063 |
0.6319 | -0.447 | 1.0 | N | 0.745 | 0.556 | 0.7175160923 | gnomAD-4.0.0 | 3.42062E-06 | None | None | None | None | I | None | 0 | 2.23624E-05 | None | 3.82702E-05 | 0 | None | 0 | 0 | 2.69799E-06 | 0 | 0 |
| R/H | 1159 |
Ig-4 |
78 | rs149883066 |
0.3787 | -1.464 | 1.0 | N | 0.637 | 0.39 | 0.380223377699 | gnomAD-2.1.1 | 2.39E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.41E-05 | 1.63345E-04 |
| R/H | 1159 |
Ig-4 |
78 | rs149883066 |
0.3787 | -1.464 | 1.0 | N | 0.637 | 0.39 | 0.380223377699 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| R/H | 1159 |
Ig-4 |
78 | rs149883066 |
0.3787 | -1.464 | 1.0 | N | 0.637 | 0.39 | 0.380223377699 | gnomAD-4.0.0 | 2.47856E-05 | None | None | None | None | I | None | 0 | 1.66678E-05 | None | 0 | 4.45871E-05 | None | 0 | 0 | 3.05103E-05 | 1.09791E-05 | 0 |
| R/L | 1159 |
Ig-4 |
78 | rs149883066 |
0.84 | 0.224 | 0.992 | N | 0.643 | 0.434 | None | gnomAD-2.1.1 | 1.59E-05 | None | None | None | None | I | None | 0 | 0 | None | 2.98033E-04 | 0 | None | 0 | None | 0 | 0 | 1.63345E-04 |
| R/L | 1159 |
Ig-4 |
78 | rs149883066 |
0.84 | 0.224 | 0.992 | N | 0.643 | 0.434 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 2.88351E-04 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/L | 1159 |
Ig-4 |
78 | rs149883066 |
0.84 | 0.224 | 0.992 | N | 0.643 | 0.434 | None | gnomAD-4.0.0 | 1.05339E-05 | None | None | None | None | I | None | 0 | 0 | None | 4.05433E-04 | 0 | None | 0 | 0 | 3.39003E-06 | 0 | 1.60046E-05 |
| R/S | 1159 |
Ig-4 |
78 | None | 0.9381 | -0.779 | 0.984 | N | 0.608 | 0.548 | 0.383590876969 | gnomAD-2.1.1 | 1.59E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.30685E-04 | None | 0 | 0 | 0 |
| R/S | 1159 |
Ig-4 |
78 | None | 0.9381 | -0.779 | 0.984 | N | 0.608 | 0.548 | 0.383590876969 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.92382E-04 | None | 0 | 0 | 0 | 0 | 0 |
| R/S | 1159 |
Ig-4 |
78 | None | 0.9381 | -0.779 | 0.984 | N | 0.608 | 0.548 | 0.383590876969 | gnomAD-4.0.0 | 6.81604E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 6.68807E-05 | None | 0 | 0 | 0 | 8.78407E-05 | 0 |
| S/N | 1367 |
Ig-5 |
77 | rs1015028448 |
0.72 | None | 0.99 | N | 0.628 | 0.247 | 0.296679040009 | gnomAD-4.0.0 | 2.05239E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69802E-06 | 0 | 0 |
| S/R | 1367 |
Ig-5 |
77 | rs1307238681 |
0.9734 | None | 0.997 | N | 0.631 | 0.435 | 0.432936702747 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 1367 |
Ig-5 |
77 | rs1307238681 |
0.9734 | None | 0.997 | N | 0.631 | 0.435 | 0.432936702747 | gnomAD-4.0.0 | 9.29453E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.27123E-05 | 0 | 0 |
| Q/H | 1533 |
Ig-6 |
77 | None | 0.4831 | None | 0.999 | N | 0.597 | 0.376 | 0.323886383625 | gnomAD-4.0.0 | 1.59105E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85709E-06 | 0 | 0 |
| Q/R | 1533 |
Ig-6 |
77 | None | 0.1767 | None | 0.98 | N | 0.597 | 0.511 | 0.224531998449 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 1633 |
Ig-7 |
78 | rs1406457857 |
0.18 | -1.053 | 0.993 | N | 0.256 | 0.278 | 0.618819884562 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| I/V | 1633 |
Ig-7 |
78 | rs1406457857 |
0.18 | -1.053 | 0.993 | N | 0.256 | 0.278 | 0.618819884562 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/V | 1633 |
Ig-7 |
78 | rs1406457857 |
0.18 | -1.053 | 0.993 | N | 0.256 | 0.278 | 0.618819884562 | gnomAD-4.0.0 | 3.84228E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.17556E-06 | 0 | 0 |
| T/I | 1780 |
Ig-8 |
78 | None | 0.4848 | None | 0.864 | N | 0.767 | 0.344 | 0.595273823551 | gnomAD-4.0.0 | 1.60137E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| E/K | 1915 |
Ig-9 |
75 | rs375388374 |
0.6349 | -0.518 | 0.994 | N | 0.62 | 0.436 | None | gnomAD-2.1.1 | 7.96E-06 | None | None | None | None | I | None | 1.23062E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 1915 |
Ig-9 |
75 | rs375388374 |
0.6349 | -0.518 | 0.994 | N | 0.62 | 0.436 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 1915 |
Ig-9 |
75 | rs375388374 |
0.6349 | -0.518 | 0.994 | N | 0.62 | 0.436 | None | gnomAD-4.0.0 | 2.56104E-06 | None | None | None | None | I | None | 3.38158E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 2154 |
Ig-10 |
77 | rs780879621 |
0.0852 | -1.009 | 0.019 | N | 0.209 | 0.044 | 0.419957187557 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/M | 2154 |
Ig-10 |
77 | rs780879621 |
0.0852 | -1.009 | 0.019 | N | 0.209 | 0.044 | 0.419957187557 | gnomAD-4.0.0 | 2.73641E-06 | None | None | None | None | N | None | 0 | 8.94614E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 2154 |
Ig-10 |
77 | rs2154345699 |
0.0614 | None | None | N | 0.089 | 0.087 | 0.276898752692 | gnomAD-4.0.0 | 2.05229E-06 | None | None | None | None | N | None | 2.98757E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79859E-06 | 0 | 0 |
| D/N | 2341 |
Ig-12 |
75 | rs781736462 |
0.0772 | 0.239 | 0.979 | N | 0.517 | 0.179 | 0.203808441222 | gnomAD-2.1.1 | 1.59E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.76E-05 | 1.63292E-04 |
| D/N | 2341 |
Ig-12 |
75 | rs781736462 |
0.0772 | 0.239 | 0.979 | N | 0.517 | 0.179 | 0.203808441222 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.30959E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| D/N | 2341 |
Ig-12 |
75 | rs781736462 |
0.0772 | 0.239 | 0.979 | N | 0.517 | 0.179 | 0.203808441222 | gnomAD-4.0.0 | 7.43525E-06 | None | None | None | None | N | None | 0 | 3.33422E-05 | None | 0 | 0 | None | 0 | 0 | 6.77978E-06 | 1.09789E-05 | 1.60036E-05 |
| D/V | 2341 |
Ig-12 |
75 | None | 0.2572 | None | 0.669 | N | 0.549 | 0.316 | 0.439445477881 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/Y | 2341 |
Ig-12 |
75 | rs781736462 |
0.1893 | 0.127 | 0.996 | N | 0.534 | 0.412 | 0.467839254973 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 2341 |
Ig-12 |
75 | rs781736462 |
0.1893 | 0.127 | 0.996 | N | 0.534 | 0.412 | 0.467839254973 | gnomAD-4.0.0 | 8.20911E-06 | None | None | None | None | N | None | 0 | 6.70961E-05 | None | 0 | 0 | None | 0 | 0 | 7.1945E-06 | 0 | 1.65579E-05 |
| P/L | 2430 |
Ig-13 |
75 | rs775687221 |
0.1968 | -0.271 | 0.993 | N | 0.609 | 0.361 | 0.750005655083 | gnomAD-2.1.1 | 7.99E-06 | None | None | None | None | I | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/L | 2430 |
Ig-13 |
75 | rs775687221 |
0.1968 | -0.271 | 0.993 | N | 0.609 | 0.361 | 0.750005655083 | gnomAD-4.0.0 | 6.36227E-06 | None | None | None | None | I | None | 0 | 6.85965E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0217E-05 |
| P/S | 2430 |
Ig-13 |
75 | rs761169279 |
0.151 | -0.754 | 0.993 | N | 0.477 | 0.425 | 0.346768085243 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| P/S | 2430 |
Ig-13 |
75 | rs761169279 |
0.151 | -0.754 | 0.993 | N | 0.477 | 0.425 | 0.346768085243 | gnomAD-4.0.0 | 1.36816E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99308E-07 | 1.15931E-05 | 0 |
| P/T | 2430 |
Ig-13 |
75 | rs761169279 |
0.1624 | -0.739 | 0.997 | N | 0.501 | 0.45 | 0.499473279415 | gnomAD-2.1.1 | 1.06E-05 | None | None | None | None | I | None | 0 | 8.47E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 2430 |
Ig-13 |
75 | rs761169279 |
0.1624 | -0.739 | 0.997 | N | 0.501 | 0.45 | 0.499473279415 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 1.30924E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 2430 |
Ig-13 |
75 | rs761169279 |
0.1624 | -0.739 | 0.997 | N | 0.501 | 0.45 | 0.499473279415 | gnomAD-4.0.0 | 2.47831E-06 | None | None | None | None | I | None | 0 | 6.66756E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 2607 |
Ig-15 |
75 | rs1214151889 |
0.768 | None | 1.0 | D | 0.811 | 0.677 | 0.667381685972 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/S | 2694 |
Ig-16 |
74 | rs1230162125 |
0.1153 | -0.395 | 1.0 | N | 0.647 | 0.353 | 0.146414634003 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| A/S | 2694 |
Ig-16 |
74 | rs1230162125 |
0.1153 | -0.395 | 1.0 | N | 0.647 | 0.353 | 0.146414634003 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| A/S | 2694 |
Ig-16 |
74 | rs1230162125 |
0.1153 | -0.395 | 1.0 | N | 0.647 | 0.353 | 0.146414634003 | gnomAD-4.0.0 | 6.57229E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| A/V | 2694 |
Ig-16 |
74 | rs754758405 |
0.4118 | -0.001 | 1.0 | N | 0.729 | 0.347 | 0.281780670237 | gnomAD-2.1.1 | 7.96E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.45E-05 | None | 3.27E-05 | None | 0 | 0 | 0 |
| A/V | 2694 |
Ig-16 |
74 | rs754758405 |
0.4118 | -0.001 | 1.0 | N | 0.729 | 0.347 | 0.281780670237 | gnomAD-4.0.0 | 3.18134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.775E-05 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| G/A | 2782 |
Ig-17 |
76 | rs2091296407 |
0.5075 | None | 1.0 | D | 0.564 | 0.558 | 0.574670332726 | gnomAD-4.0.0 | 1.36814E-06 | None | None | None | None | N | None | 0 | 4.47247E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 2782 |
Ig-17 |
76 | rs774178619 |
0.7754 | -0.454 | 1.0 | D | 0.641 | 0.713 | 0.883605920394 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| G/R | 2782 |
Ig-17 |
76 | rs774178619 |
0.7754 | -0.454 | 1.0 | D | 0.641 | 0.713 | 0.883605920394 | gnomAD-4.0.0 | 1.59055E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85649E-06 | 0 | 0 |
| G/V | 2782 |
Ig-17 |
76 | None | 0.8524 | None | 1.0 | D | 0.682 | 0.751 | 0.938928030228 | gnomAD-4.0.0 | 6.84072E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99292E-07 | 0 | 0 |
| G/V | 2956 |
Ig-19 |
75 | None | 0.9697 | None | 1.0 | D | 0.786 | 0.899 | 0.920236168323 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/E | 3132 |
Ig-21 |
75 | rs1293502713 |
0.8994 | None | 1.0 | N | 0.815 | 0.537 | 0.301789629655 | gnomAD-4.0.0 | 1.59052E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 0 | 0 | 0 |
| K/Q | 3314 |
Ig-23 |
76 | rs769286646 |
0.221 | -0.323 | 0.497 | N | 0.595 | 0.334 | 0.215869574891 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 3314 |
Ig-23 |
76 | rs769286646 |
0.221 | -0.323 | 0.497 | N | 0.595 | 0.334 | 0.215869574891 | gnomAD-4.0.0 | 1.59054E-06 | None | None | None | None | I | None | 0 | 2.28624E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 3419 |
Ig-24 |
75 | rs1266502582 |
0.1257 | -1.134 | 0.012 | D | 0.373 | 0.201 | 0.220303561663 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| S/G | 3419 |
Ig-24 |
75 | rs1266502582 |
0.1257 | -1.134 | 0.012 | D | 0.373 | 0.201 | 0.220303561663 | gnomAD-4.0.0 | 7.52528E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 8.67453E-04 | 4.49671E-06 | 0 | 1.65596E-05 |
| S/N | 3419 |
Ig-24 |
75 | rs2291310 |
0.1108 | -0.91 | None | D | 0.131 | 0.105 | None | gnomAD-2.1.1 | 8.45905E-01 | None | None | None | None | N | None | 8.44852E-01 | 5.72897E-01 | None | 9.1353E-01 | 7.69231E-01 | None | 7.88977E-01 | None | 8.91751E-01 | 9.30417E-01 | 8.75937E-01 |
| S/N | 3419 |
Ig-24 |
75 | rs2291310 |
0.1108 | -0.91 | None | D | 0.131 | 0.105 | None | gnomAD-3.1.2 | 8.73509E-01 | None | None | None | None | N | None | 8.44553E-01 | 7.19651E-01 | 9.51754E-01 | 9.18444E-01 | 7.90621E-01 | None | 8.91752E-01 | 9.49367E-01 | 9.30579E-01 | 7.90216E-01 | 8.97608E-01 |
| S/N | 3419 |
Ig-24 |
75 | rs2291310 |
0.1108 | -0.91 | None | D | 0.131 | 0.105 | None | 1000 genomes | 8.08906E-01 | None | None | None | None | N | None | 8.389E-01 | 6.7E-01 | None | None | 7.847E-01 | 9.145E-01 | None | None | None | 7.832E-01 | None |
| S/N | 3419 |
Ig-24 |
75 | rs2291310 |
0.1108 | -0.91 | None | D | 0.131 | 0.105 | None | gnomAD-4.0.0 | 9.00962E-01 | None | None | None | None | N | None | 8.45074E-01 | 6.19775E-01 | None | 9.16993E-01 | 7.91436E-01 | None | 8.89408E-01 | 9.30175E-01 | 9.31295E-01 | 7.95858E-01 | 8.97709E-01 |
| S/T | 3419 |
Ig-24 |
75 | rs2291310 |
0.1011 | None | None | N | 0.124 | 0.071 | 0.0297737177859 | gnomAD-4.0.0 | 6.84116E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| A/V | 3542 |
Ig-25 |
78 | None | 0.1036 | None | None | None | None | 0.143 | None | gnomAD-4.0.0 | 3.21352E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.78851E-06 | 0 | 0 |
| H/D | 3735 |
Ig-26 |
76 | None | 0.2035 | None | None | None | None | 0.057 | None | gnomAD-4.0.0 | 1.59136E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02389E-05 |
| H/Q | 3735 |
Ig-26 |
76 | rs1483940165 |
0.1141 | -0.289 | None | None | None | 0.083 | None | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.41026E-04 | None | 0 | None | 0 | 0 | 0 |
| H/Q | 3735 |
Ig-26 |
76 | rs1483940165 |
0.1141 | -0.289 | None | None | None | 0.083 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9216E-04 | None | 0 | 0 | 0 | 0 | 0 |
| H/Q | 3735 |
Ig-26 |
76 | rs1483940165 |
0.1141 | -0.289 | None | None | None | 0.083 | None | gnomAD-4.0.0 | 6.56953E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.9216E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 3895 |
Ig-27 |
76 | rs772765158 |
0.1179 | -0.508 | 0.997 | D | 0.508 | 0.409 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| S/C | 3895 |
Ig-27 |
76 | rs772765158 |
0.1179 | -0.508 | 0.997 | D | 0.508 | 0.409 | None | gnomAD-4.0.0 | 4.77351E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57398E-06 | 0 | 0 |
| S/N | 3895 |
Ig-27 |
76 | rs769466475 |
0.1489 | -1.102 | 0.012 | D | 0.216 | 0.192 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| S/N | 3895 |
Ig-27 |
76 | rs769466475 |
0.1489 | -1.102 | 0.012 | D | 0.216 | 0.192 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 3895 |
Ig-27 |
76 | rs769466475 |
0.1489 | -1.102 | 0.012 | D | 0.216 | 0.192 | None | gnomAD-4.0.0 | 2.85052E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.72939E-05 | 0 | 3.20215E-05 |
| S/T | 3895 |
Ig-27 |
76 | None | 0.0948 | None | 0.051 | N | 0.187 | 0.114 | None | gnomAD-4.0.0 | 1.3684E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7989E-06 | 0 | 0 |
| L/S | 4680 |
Ig-29 |
75 | None | 0.076 | None | None | N | 0.291 | 0.09 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 4870 |
Ig-31 |
76 | None | 0.3418 | None | 0.999 | D | 0.823 | 0.464 | 0.769190748641 | gnomAD-4.0.0 | 1.59142E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02499E-05 |
| S/P | 4963 |
Ig-32 |
76 | rs754692297 |
0.863 | -0.462 | 0.966 | D | 0.46 | 0.413 | 0.480274617672 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.44E-05 | None | 0 | 0 | 0 |
| S/P | 4963 |
Ig-32 |
76 | rs754692297 |
0.863 | -0.462 | 0.966 | D | 0.46 | 0.413 | 0.480274617672 | gnomAD-4.0.0 | 4.81869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.39947E-05 | 0 |
| V/L | 5057 |
Ig-33 |
77 | None | 0.1033 | None | None | N | 0.097 | 0.116 | 0.304108284078 | gnomAD-4.0.0 | 1.5924E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.88274E-05 | 0 | 0 | 0 | 0 |
| A/T | 5150 |
Ig-34 |
76 | None | 0.0821 | None | 0.956 | N | 0.617 | 0.284 | 0.402899589544 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/V | 5150 |
Ig-34 |
76 | None | 0.1451 | None | 0.989 | N | 0.672 | 0.387 | 0.65763613582 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| T/R | 5432 |
Ig-37 |
76 | None | 0.2036 | None | 0.997 | D | 0.705 | 0.397 | 0.856718553135 | gnomAD-4.0.0 | 1.59238E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.88445E-05 | 0 | 0 | 0 | 0 |
| S/I | 5525 |
Ig-38 |
76 | None | 0.1854 | None | 0.667 | N | 0.699 | 0.349 | 0.645206814577 | gnomAD-4.0.0 | 1.36918E-06 | None | None | None | None | N | None | 5.98516E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 5525 |
Ig-38 |
76 | None | 0.5258 | None | 0.497 | D | 0.609 | 0.208 | 0.478680857624 | gnomAD-4.0.0 | 1.59319E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86143E-06 | 0 | 0 |
| S/T | 5525 |
Ig-38 |
76 | rs727503649 |
0.0785 | None | 0.22 | N | 0.596 | 0.089 | None | gnomAD-4.0.0 | 6.84592E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65788E-05 |
| Q/E | 5619 |
Ig-39 |
77 | None | 0.0923 | None | 0.27 | N | 0.257 | 0.115 | 0.313518423057 | gnomAD-4.0.0 | 1.59288E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86171E-06 | 0 | 0 |
| Q/K | 5898 |
Ig-42 |
76 | rs1462892188 |
0.1114 | -0.102 | 0.425 | N | 0.333 | 0.184 | 0.151104730317 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
| T/S | 5994 |
Ig-43 |
76 | rs751239780 |
0.1056 | -0.873 | 0.961 | N | 0.554 | 0.271 | 0.273938319068 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.32234E-04 | 0 | 0 |
| T/S | 5994 |
Ig-43 |
76 | rs751239780 |
0.1056 | -0.873 | 0.961 | N | 0.554 | 0.271 | 0.273938319068 | gnomAD-4.0.0 | 7.96024E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.4123E-05 | 0 | 0 | 0 | 0 |
| S/N | 6087 |
Ig-44 |
76 | rs1270956493 |
0.1306 | None | 0.684 | N | 0.429 | 0.283 | 0.270001397563 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 6087 |
Ig-44 |
76 | rs1270956493 |
0.1306 | None | 0.684 | N | 0.429 | 0.283 | 0.270001397563 | gnomAD-4.0.0 | 6.59457E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47258E-05 | 0 | 0 |
| R/L | 6181 |
Ig-45 |
77 | rs201951252 |
0.1406 | None | 0.251 | N | 0.534 | 0.296 | 0.470648230714 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/L | 6181 |
Ig-45 |
77 | rs201951252 |
0.1406 | None | 0.251 | N | 0.534 | 0.296 | 0.470648230714 | gnomAD-4.0.0 | 1.23944E-06 | None | None | None | None | I | None | 0 | 3.33411E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 6181 |
Ig-45 |
77 | rs201951252 |
0.064 | -0.58 | 0.005 | N | 0.247 | 0.133 | None | gnomAD-2.1.1 | 2.14E-05 | None | None | None | None | I | None | 1.65358E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| R/Q | 6181 |
Ig-45 |
77 | rs201951252 |
0.064 | -0.58 | 0.005 | N | 0.247 | 0.133 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | I | None | 1.6887E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/Q | 6181 |
Ig-45 |
77 | rs201951252 |
0.064 | -0.58 | 0.005 | N | 0.247 | 0.133 | None | gnomAD-4.0.0 | 2.78874E-05 | None | None | None | None | I | None | 1.73537E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 2.7125E-05 | 0 | 0 |
| S/P | 6274 |
Ig-46 |
76 | None | 0.8907 | None | 0.497 | N | 0.523 | 0.353 | 0.126345400529 | gnomAD-4.0.0 | 2.05339E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79958E-06 | 1.15969E-05 | 0 |
| K/N | 6367 |
Ig-47 |
76 | rs769617600 |
0.4746 | 0.037 | 0.642 | N | 0.338 | 0.262 | 0.236890367714 | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| K/N | 6367 |
Ig-47 |
76 | rs769617600 |
0.4746 | 0.037 | 0.642 | N | 0.338 | 0.262 | 0.236890367714 | gnomAD-4.0.0 | 1.30189E-05 | None | None | None | None | I | None | 0 | 2.24487E-05 | None | 0 | 0 | None | 0 | 0 | 1.62051E-05 | 0 | 0 |
| E/G | 6460 |
Ig-48 |
76 | rs766551817 |
0.3152 | -1.543 | 0.165 | N | 0.574 | 0.185 | 0.353548585375 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| E/G | 6460 |
Ig-48 |
76 | rs766551817 |
0.3152 | -1.543 | 0.165 | N | 0.574 | 0.185 | 0.353548585375 | gnomAD-4.0.0 | 2.73873E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69962E-06 | 0 | 1.6581E-05 |
| E/V | 6460 |
Ig-48 |
76 | None | 0.391 | None | 0.324 | N | 0.576 | 0.215 | 0.348764635752 | gnomAD-4.0.0 | 6.84682E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99875E-07 | 0 | 0 |
| S/L | 6556 |
Ig-49 |
76 | rs2154306280 |
0.1106 | None | 0.042 | N | 0.511 | 0.201 | 0.621426341079 | gnomAD-4.0.0 | 2.33534E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.06722E-05 | 0 | 0 |
| S/P | 6556 |
Ig-49 |
76 | None | 0.8964 | None | 0.301 | N | 0.431 | 0.335 | 0.379881503574 | gnomAD-4.0.0 | 1.6052E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.45012E-05 | 0 |
| T/I | 6649 |
Ig-50 |
76 | rs767035458 |
0.1937 | -0.013 | 0.351 | D | 0.46 | 0.261 | 0.537402380065 | gnomAD-2.1.1 | 4.2E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.17E-06 | 0 |
| T/I | 6649 |
Ig-50 |
76 | rs767035458 |
0.1937 | -0.013 | 0.351 | D | 0.46 | 0.261 | 0.537402380065 | gnomAD-4.0.0 | 1.62667E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9108E-06 | 0 | 0 |
| Q/H | 6743 |
Ig-51 |
77 | rs1354673910 |
0.1128 | -0.683 | None | N | 0.115 | 0.131 | 0.154104182512 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.01E-06 | 0 |
| Q/H | 6743 |
Ig-51 |
77 | rs1354673910 |
0.1128 | -0.683 | None | N | 0.115 | 0.131 | 0.154104182512 | gnomAD-4.0.0 | 5.51483E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.24158E-06 | 0 | 0 |
| Q/R | 6743 |
Ig-51 |
77 | rs794729620 |
0.0715 | None | 0.001 | N | 0.12 | 0.08 | 0.119812018005 | gnomAD-4.0.0 | 1.37835E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.81002E-06 | 0 | 0 |
| K/E | 6930 |
Ig-53 |
77 | None | 0.2988 | None | 0.042 | N | 0.274 | 0.148 | 0.264547087235 | gnomAD-4.0.0 | 1.60563E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.88391E-06 | 0 | 0 |
| Q/P | 7023 |
Ig-54 |
76 | rs753621469 |
0.812 | 0.062 | 0.784 | N | 0.479 | 0.389 | 0.440077040801 | gnomAD-2.1.1 | 7.14E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| Q/P | 7023 |
Ig-54 |
76 | rs753621469 |
0.812 | 0.062 | 0.784 | N | 0.479 | 0.389 | 0.440077040801 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Q/P | 7023 |
Ig-54 |
76 | rs753621469 |
0.812 | 0.062 | 0.784 | N | 0.479 | 0.389 | 0.440077040801 | gnomAD-4.0.0 | 5.57834E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.62959E-06 | 0 | 0 |
| A/T | 7119 |
Ig-55 |
76 | rs1254360704 |
0.0744 | -0.511 | 0.022 | N | 0.116 | 0.19 | 0.233150807113 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| A/T | 7119 |
Ig-55 |
76 | rs1254360704 |
0.0744 | -0.511 | 0.022 | N | 0.116 | 0.19 | 0.233150807113 | gnomAD-4.0.0 | 1.59262E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86118E-06 | 0 | 0 |
| A/V | 7119 |
Ig-55 |
76 | None | 0.1417 | None | 0.051 | N | 0.273 | 0.237 | 0.410469974859 | gnomAD-4.0.0 | 1.59253E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02608E-05 |
| S/F | 7212 |
Ig-56 |
76 | None | 0.1622 | None | 0.794 | N | 0.563 | 0.338 | 0.682465373879 | gnomAD-4.0.0 | 2.05334E-06 | None | None | None | None | N | None | 2.98954E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79926E-06 | 0 | 0 |
| E/A | 7305 |
Ig-57 |
76 | rs1553911785 |
0.1217 | None | 0.042 | N | 0.402 | 0.209 | 0.332902724076 | gnomAD-4.0.0 | 6.36687E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.10951E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 7305 |
Ig-57 |
76 | rs763316110 |
0.2003 | -0.955 | 0.175 | D | 0.285 | 0.061 | 0.218112801441 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/D | 7305 |
Ig-57 |
76 | rs763316110 |
0.2003 | -0.955 | 0.175 | D | 0.285 | 0.061 | 0.218112801441 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 7305 |
Ig-57 |
76 | rs763316110 |
0.2003 | -0.955 | 0.175 | D | 0.285 | 0.061 | 0.218112801441 | gnomAD-4.0.0 | 6.40681E-06 | None | None | None | None | I | None | 8.45823E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 7494 |
Ig-59 |
76 | None | 0.1886 | None | 0.998 | D | 0.491 | 0.411 | 0.649418150632 | gnomAD-4.0.0 | 6.85514E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00619E-07 | 0 | 0 |
| S/Y | 7494 |
Ig-59 |
76 | rs778434653 |
0.1913 | -0.769 | 0.995 | N | 0.585 | 0.405 | 0.776041197187 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | I | None | 6.51E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.81E-05 | 0 |
| S/Y | 7494 |
Ig-59 |
76 | rs778434653 |
0.1913 | -0.769 | 0.995 | N | 0.585 | 0.405 | 0.776041197187 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/Y | 7494 |
Ig-59 |
76 | rs778434653 |
0.1913 | -0.769 | 0.995 | N | 0.585 | 0.405 | 0.776041197187 | gnomAD-4.0.0 | 1.05531E-05 | None | None | None | None | I | None | 1.33668E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35782E-05 | 0 | 0 |
| T/A | 7590 |
Ig-60 |
76 | None | 0.0749 | None | 0.099 | D | 0.329 | 0.185 | 0.28058544554 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/N | 7590 |
Ig-60 |
76 | rs1486219064 |
0.1299 | None | 0.379 | N | 0.429 | 0.301 | 0.461323234107 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 7590 |
Ig-60 |
76 | rs1486219064 |
0.1299 | None | 0.379 | N | 0.429 | 0.301 | 0.461323234107 | gnomAD-4.0.0 | 6.57142E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47011E-05 | 0 | 0 |
| H/Y | 7684 |
Ig-61 |
77 | rs759120198 |
0.1002 | 0.887 | 0.643 | N | 0.379 | 0.24 | 0.364926071151 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| H/Y | 7684 |
Ig-61 |
77 | rs759120198 |
0.1002 | 0.887 | 0.643 | N | 0.379 | 0.24 | 0.364926071151 | gnomAD-4.0.0 | 2.06281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.04311E-07 | 2.32775E-05 | 0 |
| T/A | 7777 |
Ig-62 |
76 | None | 0.0805 | None | None | N | 0.099 | 0.118 | 0.0884992946249 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43336E-05 | 0 |
| K/I | 7871 |
Ig-63 |
77 | None | 0.7491 | None | 0.002 | D | 0.519 | 0.341 | 0.482137172311 | gnomAD-4.0.0 | 1.36896E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99747E-07 | 1.15982E-05 | 0 |
| T/A | 8153 |
Ig-66 |
76 | None | 0.0923 | None | None | D | 0.156 | 0.291 | 0.187945064343 | gnomAD-4.0.0 | 1.59128E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88232E-05 | 0 | 0 | 0 | 0 |
| E/K | 8246 |
Ig-67 |
76 | rs578260569 |
0.1026 | -0.008 | 0.27 | N | 0.283 | 0.186 | None | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 2.61558E-04 | None | 0 | 0 | 0 |
| E/K | 8246 |
Ig-67 |
76 | rs578260569 |
0.1026 | -0.008 | 0.27 | N | 0.283 | 0.186 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06954E-04 | 0 |
| E/K | 8246 |
Ig-67 |
76 | rs578260569 |
0.1026 | -0.008 | 0.27 | N | 0.283 | 0.186 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| E/K | 8246 |
Ig-67 |
76 | rs578260569 |
0.1026 | -0.008 | 0.27 | N | 0.283 | 0.186 | None | gnomAD-4.0.0 | 1.67307E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47649E-07 | 2.85488E-04 | 0 |
| D/E | 8339 |
Ig-68 |
76 | rs1283273345 |
0.0517 | -0.57 | None | N | 0.082 | 0.171 | 0.0297737177859 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| D/E | 8339 |
Ig-68 |
76 | rs1283273345 |
0.0517 | -0.57 | None | N | 0.082 | 0.171 | 0.0297737177859 | gnomAD-4.0.0 | 4.77458E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57716E-06 | 0 | 0 |
| Q/L | 8905 |
Ig-74 |
76 | None | 0.1054 | None | 0.113 | N | 0.557 | 0.201 | 0.443695250439 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/G | 9094 |
Ig-76 |
76 | rs768623560 |
0.1056 | -1.452 | 0.117 | N | 0.441 | 0.269 | 0.20549828249 | gnomAD-2.1.1 | 1.79E-05 | None | None | None | None | N | None | 0 | 1.41571E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/G | 9094 |
Ig-76 |
76 | rs768623560 |
0.1056 | -1.452 | 0.117 | N | 0.441 | 0.269 | 0.20549828249 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 9094 |
Ig-76 |
76 | rs768623560 |
0.1056 | -1.452 | 0.117 | N | 0.441 | 0.269 | 0.20549828249 | gnomAD-4.0.0 | 5.12397E-06 | None | None | None | None | N | None | 0 | 6.77805E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/I | 9094 |
Ig-76 |
76 | None | 0.1687 | None | 0.004 | D | 0.465 | 0.176 | 0.404315859256 | gnomAD-4.0.0 | 1.59136E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85847E-06 | 0 | 0 |
| S/N | 9094 |
Ig-76 |
76 | rs1256219559 |
0.124 | -0.624 | 0.117 | N | 0.508 | 0.223 | 0.151104730317 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 9094 |
Ig-76 |
76 | rs1256219559 |
0.124 | -0.624 | 0.117 | N | 0.508 | 0.223 | 0.151104730317 | gnomAD-4.0.0 | 1.59136E-06 | None | None | None | None | N | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 9187 |
Ig-77 |
76 | rs796818398 |
0.2653 | -0.777 | 0.005 | N | 0.116 | 0.05 | 0.208816687407 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| E/D | 9187 |
Ig-77 |
76 | rs796818398 |
0.2653 | -0.777 | 0.005 | N | 0.116 | 0.05 | 0.208816687407 | gnomAD-4.0.0 | 2.73685E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59783E-06 | 0 | 0 |
| E/K | 9187 |
Ig-77 |
76 | rs1195527997 |
0.1628 | 0.123 | 0.012 | N | 0.141 | 0.235 | 0.273938319068 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 9187 |
Ig-77 |
76 | rs1195527997 |
0.1628 | 0.123 | 0.012 | N | 0.141 | 0.235 | 0.273938319068 | gnomAD-4.0.0 | 1.59133E-06 | None | None | None | None | N | None | 0 | 2.28634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 9280 |
Ig-78 |
76 | None | 0.1943 | None | 0.999 | N | 0.692 | 0.597 | 0.57347888143 | gnomAD-4.0.0 | 1.59669E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87061E-06 | 0 | 0 |
| T/A | 9376 |
Ig-79 |
76 | None | 0.0818 | None | 0.002 | None | 0.101 | 0.23 | 0.177238962908 | gnomAD-4.0.0 | 3.18384E-06 | None | None | None | None | N | None | 0 | 2.28718E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02499E-05 |
| T/K | 9376 |
Ig-79 |
76 | None | 0.1733 | None | 0.549 | None | 0.374 | 0.34 | 0.457106177737 | gnomAD-4.0.0 | 6.84347E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99596E-07 | 0 | 0 |
| T/R | 9376 |
Ig-79 |
76 | rs749875409 |
0.1303 | -0.048 | 0.81 | None | 0.447 | 0.433 | 0.66854072215 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63773E-04 | None | 0 | 2.67E-05 | 0 |
| T/R | 9376 |
Ig-79 |
76 | rs749875409 |
0.1303 | -0.048 | 0.81 | None | 0.447 | 0.433 | 0.66854072215 | gnomAD-4.0.0 | 1.64243E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73491E-04 | 7.19677E-06 | 1.39243E-04 | 4.97067E-05 |
| V/G | 9472 |
Ig-80 |
76 | rs1257120493 |
0.1209 | -1.884 | 0.003 | None | 0.317 | 0.341 | 0.6276227268 | gnomAD-2.1.1 | 1.2E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.66908E-04 | None | 0 | None | 0 | 0 | 0 |
| V/G | 9472 |
Ig-80 |
76 | rs1257120493 |
0.1209 | -1.884 | 0.003 | None | 0.317 | 0.341 | 0.6276227268 | gnomAD-4.0.0 | 3.4225E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.25951E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 9472 |
Ig-80 |
76 | None | 0.1534 | None | 0.029 | None | 0.255 | 0.161 | 0.464784125046 | gnomAD-4.0.0 | 1.20032E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-05 | 0 | 0 |
| F/C | 9774 |
Ig-83 |
77 | rs2075902617 |
0.5262 | None | 0.851 | None | 0.536 | 0.326 | 0.689188209222 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/C | 9774 |
Ig-83 |
77 | rs2075902617 |
0.5262 | None | 0.851 | None | 0.536 | 0.326 | 0.689188209222 | gnomAD-4.0.0 | 6.57575E-06 | None | None | None | None | I | None | 2.41523E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/C | 9976 |
Ig-84 |
77 | None | 0.9975 | None | 1.0 | None | 0.653 | 0.667 | 0.729388315074 | gnomAD-4.0.0 | 1.59247E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86053E-06 | 0 | 0 |
| G/D | 9976 |
Ig-84 |
77 | rs1183241604 |
0.998 | -0.906 | 1.0 | None | 0.681 | 0.593 | 0.490074841992 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| G/D | 9976 |
Ig-84 |
77 | rs1183241604 |
0.998 | -0.906 | 1.0 | None | 0.681 | 0.593 | 0.490074841992 | gnomAD-4.0.0 | 2.73784E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.5989E-06 | 0 | 0 |
| R/L | 10152 |
Ig-86 |
75 | rs375796685 |
0.7977 | 0.57 | 0.975 | None | 0.637 | 0.376 | 0.709553313446 | gnomAD-2.1.1 | 1.6E-05 | None | None | None | None | I | None | 0 | 1.15861E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/L | 10152 |
Ig-86 |
75 | rs375796685 |
0.7977 | 0.57 | 0.975 | None | 0.637 | 0.376 | 0.709553313446 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/L | 10152 |
Ig-86 |
75 | rs375796685 |
0.7977 | 0.57 | 0.975 | None | 0.637 | 0.376 | 0.709553313446 | gnomAD-4.0.0 | 6.19649E-06 | None | None | None | None | I | None | 0 | 1.00017E-04 | None | 0 | 0 | None | 0 | 0 | 8.47538E-07 | 0 | 4.80323E-05 |
| R/Q | 10152 |
Ig-86 |
75 | rs375796685 |
0.3627 | 0.056 | 0.998 | None | 0.709 | 0.295 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.42E-05 | 0 |
| R/Q | 10152 |
Ig-86 |
75 | rs375796685 |
0.3627 | 0.056 | 0.998 | None | 0.709 | 0.295 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/Q | 10152 |
Ig-86 |
75 | rs375796685 |
0.3627 | 0.056 | 0.998 | None | 0.709 | 0.295 | None | gnomAD-4.0.0 | 1.42519E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.77983E-05 | 1.09789E-05 | 1.60108E-05 |
| R/W | 10152 |
Ig-86 |
75 | rs1005491217 |
0.6983 | -0.589 | 1.0 | None | 0.762 | 0.345 | 0.473458370588 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.85E-06 | 0 |
| R/W | 10152 |
Ig-86 |
75 | rs1005491217 |
0.6983 | -0.589 | 1.0 | None | 0.762 | 0.345 | 0.473458370588 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/W | 10152 |
Ig-86 |
75 | rs1005491217 |
0.6983 | -0.589 | 1.0 | None | 0.762 | 0.345 | 0.473458370588 | gnomAD-4.0.0 | 9.29483E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.2713E-05 | 0 | 0 |
| R/C | 13761 |
Ig-87 |
78 | rs376166350 |
0.5988 | None | 0.998 | D | 0.555 | 0.376 | None | gnomAD-4.0.0 | 2.05442E-06 | None | None | None | None | I | None | 2.99312E-05 | 0 | None | 0 | 2.52908E-05 | None | 0 | 0 | 0 | 1.16217E-05 | 0 |
| R/H | 13761 |
Ig-87 |
78 | rs781139091 |
0.2165 | -0.844 | 0.98 | N | 0.573 | 0.284 | 0.311387274539 | gnomAD-2.1.1 | 3.95E-05 | None | None | None | None | I | None | 4.14E-05 | 0 | None | 0 | 5.17E-05 | None | 1.31648E-04 | None | 0 | 3.14E-05 | 1.41243E-04 |
| R/H | 13761 |
Ig-87 |
78 | rs781139091 |
0.2165 | -0.844 | 0.98 | N | 0.573 | 0.284 | 0.311387274539 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| R/H | 13761 |
Ig-87 |
78 | rs781139091 |
0.2165 | -0.844 | 0.98 | N | 0.573 | 0.284 | 0.311387274539 | gnomAD-4.0.0 | 2.7913E-05 | None | None | None | None | I | None | 1.33636E-05 | 1.66978E-05 | None | 0 | 4.47507E-05 | None | 0 | 0 | 1.61148E-05 | 2.09182E-04 | 4.80846E-05 |
| E/K | 13855 |
Ig-88 |
76 | rs780563642 |
0.446 | 0.254 | 0.977 | N | 0.637 | 0.252 | 0.181679512989 | gnomAD-2.1.1 | 8.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| E/K | 13855 |
Ig-88 |
76 | rs780563642 |
0.446 | 0.254 | 0.977 | N | 0.637 | 0.252 | 0.181679512989 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| E/K | 13855 |
Ig-88 |
76 | rs780563642 |
0.446 | 0.254 | 0.977 | N | 0.637 | 0.252 | 0.181679512989 | gnomAD-4.0.0 | 9.31086E-06 | None | None | None | None | N | None | 1.33633E-05 | 1.67045E-05 | None | 0 | 0 | None | 0 | 0 | 1.01869E-05 | 0 | 1.60411E-05 |
| L/F | 14039 |
Ig-90 |
75 | None | 0.2442 | None | 0.001 | N | 0.397 | 0.057 | 0.170165803431 | gnomAD-4.0.0 | 2.73785E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69921E-06 | 1.16007E-05 | 0 |
| E/D | 14127 |
Ig-91 |
74 | rs750100548 |
0.0972 | -0.045 | 0.001 | N | 0.193 | 0.029 | 0.0297737177859 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.66E-05 | None | 0 | None | 0 | 0 | 0 |
| E/D | 14127 |
Ig-91 |
74 | rs750100548 |
0.0972 | -0.045 | 0.001 | N | 0.193 | 0.029 | 0.0297737177859 | gnomAD-4.0.0 | 1.37107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.53024E-05 | None | 0 | 0 | 9.00051E-07 | 0 | 0 |
| E/Q | 14127 |
Ig-91 |
74 | None | 0.2468 | None | 0.324 | N | 0.46 | 0.15 | 0.132336055621 | gnomAD-4.0.0 | 1.59794E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.42365E-04 | 0 | 0 | 0 |
| K/Q | 14216 |
Ig-92 |
75 | rs1450576387 |
0.2067 | 0.219 | 0.999 | N | 0.713 | 0.24 | 0.201204373187 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| K/Q | 14216 |
Ig-92 |
75 | rs1450576387 |
0.2067 | 0.219 | 0.999 | N | 0.713 | 0.24 | 0.201204373187 | gnomAD-4.0.0 | 2.05315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69881E-06 | 0 | 0 |
| G/D | 14304 |
Ig-93 |
74 | None | 0.3653 | None | 0.997 | D | 0.77 | 0.434 | 0.348324211639 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 14482 |
Ig-95 |
75 | None | 0.5627 | None | 0.999 | N | 0.663 | 0.418 | 0.549796516352 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| M/L | 14571 |
Ig-96 |
75 | None | 0.1547 | None | 0.005 | N | 0.171 | 0.192 | 0.580864329964 | gnomAD-4.0.0 | 6.86579E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01448E-07 | 0 | 0 |
| M/T | 14571 |
Ig-96 |
75 | rs910523235 |
0.5446 | None | 0.959 | N | 0.453 | 0.387 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/T | 14571 |
Ig-96 |
75 | rs910523235 |
0.5446 | None | 0.959 | N | 0.453 | 0.387 | None | gnomAD-4.0.0 | 2.23789E-05 | None | None | None | None | N | None | 1.33626E-05 | 1.68203E-05 | None | 0 | 0 | None | 0 | 0 | 2.80286E-05 | 0 | 1.60576E-05 |
| M/V | 14571 |
Ig-96 |
75 | rs373801238 |
0.2213 | 0.112 | 0.704 | N | 0.379 | 0.174 | None | gnomAD-2.1.1 | 1.25E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.76E-05 | 0 |
| M/V | 14571 |
Ig-96 |
75 | rs373801238 |
0.2213 | 0.112 | 0.704 | N | 0.379 | 0.174 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/V | 14571 |
Ig-96 |
75 | rs373801238 |
0.2213 | 0.112 | 0.704 | N | 0.379 | 0.174 | None | gnomAD-4.0.0 | 3.10831E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.24698E-06 | 0 | 0 |
| G/R | 14660 |
Ig-97 |
75 | rs762795774 |
0.2909 | -0.016 | 0.008 | D | 0.379 | 0.252 | 0.479208069955 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| G/R | 14660 |
Ig-97 |
75 | rs762795774 |
0.2909 | -0.016 | 0.008 | D | 0.379 | 0.252 | 0.479208069955 | gnomAD-4.0.0 | 1.36885E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79921E-06 | 0 | 0 |
| R/S | 15016 |
Ig-101 |
75 | None | 0.3295 | None | 0.062 | N | 0.563 | 0.142 | 0.234412748748 | gnomAD-4.0.0 | 1.59483E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43427E-05 | 0 |
| R/T | 15016 |
Ig-101 |
75 | None | 0.2147 | None | 0.117 | N | 0.555 | 0.146 | 0.245101548738 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| P/R | 15105 |
Ig-102 |
75 | None | 0.2439 | None | 0.999 | N | 0.799 | 0.363 | 0.655515966292 | gnomAD-4.0.0 | 1.59408E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86307E-06 | 0 | 0 |
| G/R | 15194 |
Ig-103 |
75 | rs747277540 |
0.9112 | -0.512 | 1.0 | D | 0.632 | 0.584 | 0.705405603352 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| G/R | 15194 |
Ig-103 |
75 | rs747277540 |
0.9112 | -0.512 | 1.0 | D | 0.632 | 0.584 | 0.705405603352 | gnomAD-4.0.0 | 4.78126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72315E-06 | 0 | 3.02883E-05 |
| T/A | 15282 |
Ig-104 |
75 | rs1248616113 |
0.1145 | None | 0.046 | D | 0.285 | 0.194 | 0.314417295294 | gnomAD-4.0.0 | 4.79218E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29941E-06 | 0 | 0 |
| G/E | 15376 |
Ig-105 |
75 | None | 0.6905 | None | 0.991 | N | 0.827 | 0.43 | 0.397391247328 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 15376 |
Ig-105 |
75 | rs1370978801 |
0.6656 | -0.543 | 0.998 | N | 0.84 | 0.426 | 0.588350616613 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| G/R | 15376 |
Ig-105 |
75 | rs1370978801 |
0.6656 | -0.543 | 0.998 | N | 0.84 | 0.426 | 0.588350616613 | gnomAD-4.0.0 | 1.36974E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00108E-07 | 1.16112E-05 | 0 |
| E/G | 15465 |
Ig-106 |
75 | rs773523242 |
0.1807 | -0.536 | 0.22 | N | 0.597 | 0.311 | 0.33110744837 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/G | 15465 |
Ig-106 |
75 | rs773523242 |
0.1807 | -0.536 | 0.22 | N | 0.597 | 0.311 | 0.33110744837 | gnomAD-4.0.0 | 1.59546E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43538E-05 | 0 |
| Q/R | 15640 |
Ig-108 |
73 | None | 0.0811 | None | 0.006 | N | 0.13 | 0.2 | 0.20549828249 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/A | 16334 |
Ig-110 |
73 | None | 0.3039 | None | 0.201 | N | 0.412 | 0.199 | 0.446310458034 | gnomAD-4.0.0 | 1.59507E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43653E-05 | 0 |
| V/M | 16334 |
Ig-110 |
73 | rs541384076 |
0.1909 | -0.417 | 0.036 | D | 0.272 | 0.256 | 0.432379865206 | gnomAD-2.1.1 | 7.68E-05 | None | None | None | None | I | None | 0 | 2.03737E-04 | None | 0 | 0 | None | 3.28774E-04 | None | 0 | 0 | 3.33778E-04 |
| V/M | 16334 |
Ig-110 |
73 | rs541384076 |
0.1909 | -0.417 | 0.036 | D | 0.272 | 0.256 | 0.432379865206 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14766E-04 | 0 |
| V/M | 16334 |
Ig-110 |
73 | rs541384076 |
0.1909 | -0.417 | 0.036 | D | 0.272 | 0.256 | 0.432379865206 | 1000 genomes | 5.99042E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 3.1E-03 | None |
| V/M | 16334 |
Ig-110 |
73 | rs541384076 |
0.1909 | -0.417 | 0.036 | D | 0.272 | 0.256 | 0.432379865206 | gnomAD-4.0.0 | 2.66757E-05 | None | None | None | None | I | None | 0 | 1.50296E-04 | None | 0 | 0 | None | 0 | 0 | 8.48247E-07 | 3.08126E-04 | 8.01462E-05 |
| E/A | 17352 |
Ig-112 |
102 | rs1187111699 |
0.2406 | None | 0.999 | D | 0.677 | 0.591 | 0.467416895013 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| E/K | 17352 |
Ig-112 |
102 | None | 0.2422 | None | 0.999 | N | 0.644 | 0.416 | 0.407632638399 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.17284E-04 | 0 | 0 | 0 |
| S/P | 18048 |
Ig-114 |
81 | rs878999356 |
0.986 | -0.369 | 0.638 | N | 0.761 | 0.48 | None | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.6E-05 | 0 |
| S/P | 18048 |
Ig-114 |
81 | rs878999356 |
0.986 | -0.369 | 0.638 | N | 0.761 | 0.48 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.42E-05 | 0 | 0 |
| S/P | 18048 |
Ig-114 |
81 | rs878999356 |
0.986 | -0.369 | 0.638 | N | 0.761 | 0.48 | None | gnomAD-4.0.0 | 6.28136E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.13293E-05 | 0 | 8.16204E-05 | 0 | 4.82176E-05 |
| K/Q | 18462 |
Ig-115 |
81 | rs747050691 |
0.172 | -0.129 | 1.0 | N | 0.765 | 0.283 | 0.361958692863 | gnomAD-2.1.1 | 2.45E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 3.4118E-04 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 18462 |
Ig-115 |
81 | rs747050691 |
0.172 | -0.129 | 1.0 | N | 0.765 | 0.283 | 0.361958692863 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| K/Q | 18462 |
Ig-115 |
81 | rs747050691 |
0.172 | -0.129 | 1.0 | N | 0.765 | 0.283 | 0.361958692863 | gnomAD-4.0.0 | 4.97053E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.11877E-04 | None | 0 | 0 | 0 | 2.22851E-05 | 1.60591E-05 |
| V/I | 18767 |
Ig-116 |
80 | rs1275550493 |
0.0722 | -0.287 | 0.081 | N | 0.334 | 0.09 | 0.528409864224 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 6.51042E-04 | None | 0 | None | 0 | 0 | 0 |
| V/I | 18767 |
Ig-116 |
80 | rs1275550493 |
0.0722 | -0.287 | 0.081 | N | 0.334 | 0.09 | 0.528409864224 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.93949E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 18767 |
Ig-116 |
80 | rs1275550493 |
0.0722 | -0.287 | 0.081 | N | 0.334 | 0.09 | 0.528409864224 | gnomAD-4.0.0 | 2.03024E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.13817E-04 | None | 0 | 0 | 1.20501E-06 | 0 | 0 |
| E/A | 19462 |
Ig-118 |
72 | None | 0.2594 | None | 0.999 | N | 0.707 | 0.445 | 0.468669884856 | gnomAD-4.0.0 | 6.84284E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99543E-07 | 0 | 0 |
| E/Q | 19462 |
Ig-118 |
72 | None | 0.1414 | None | 1.0 | N | 0.651 | 0.312 | 0.445210270852 | gnomAD-4.0.0 | 1.59168E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85904E-06 | 0 | 0 |
| E/V | 19462 |
Ig-118 |
72 | rs781204863 |
0.3531 | -0.085 | 1.0 | D | 0.749 | 0.515 | 0.49908893446 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 9.28E-05 | 1.78E-05 | 0 |
| E/V | 19462 |
Ig-118 |
72 | rs781204863 |
0.3531 | -0.085 | 1.0 | D | 0.749 | 0.515 | 0.49908893446 | gnomAD-4.0.0 | 6.15855E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 5.61777E-05 | 0 | 2.69863E-06 | 0 | 4.97051E-05 |
| E/D | 19860 |
Ig-119 |
71 | rs757011726 |
0.3728 | -1.206 | 0.999 | D | 0.548 | 0.204 | 0.476832112026 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/D | 19860 |
Ig-119 |
71 | rs757011726 |
0.3728 | -1.206 | 0.999 | D | 0.548 | 0.204 | 0.476832112026 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 19860 |
Ig-119 |
71 | rs757011726 |
0.3728 | -1.206 | 0.999 | D | 0.548 | 0.204 | 0.476832112026 | gnomAD-4.0.0 | 6.57488E-06 | None | None | None | None | N | None | 2.41278E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 19860 |
Ig-119 |
71 | None | 0.2554 | None | 0.999 | N | 0.667 | 0.397 | 0.411001663086 | gnomAD-4.0.0 | 2.73746E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59842E-06 | 0 | 0 |
| V/L | 21249 |
Ig-123 |
73 | None | 0.1752 | None | 0.826 | N | 0.443 | 0.178 | 0.52540932818 | gnomAD-4.0.0 | 1.36984E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79996E-06 | 0 | 0 |
| V/M | 21249 |
Ig-123 |
73 | None | 0.1511 | None | 0.996 | N | 0.475 | 0.275 | 0.610882576163 | gnomAD-4.0.0 | 3.4246E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49989E-06 | 0 | 0 |
| E/K | 21939 |
Ig-125 |
74 | None | 0.129 | None | 0.989 | N | 0.615 | 0.38 | 0.393623145366 | gnomAD-4.0.0 | 7.12946E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.26219E-07 | 0 | 0 |
| E/Q | 21939 |
Ig-125 |
74 | None | 0.1018 | None | 0.998 | N | 0.645 | 0.226 | 0.496957384516 | gnomAD-4.0.0 | 7.12946E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.26219E-07 | 0 | 0 |
| E/K | 22337 |
Ig-126 |
73 | rs764858373 |
0.4259 | 0.093 | 0.944 | D | 0.612 | 0.387 | 0.420939154896 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| K/E | 22626 |
Ig-127 |
67 | rs763810229 |
0.1739 | 0.417 | 0.939 | N | 0.622 | 0.329 | 0.314417295294 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| K/E | 22626 |
Ig-127 |
67 | rs763810229 |
0.1739 | 0.417 | 0.939 | N | 0.622 | 0.329 | 0.314417295294 | gnomAD-4.0.0 | 8.21192E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.07951E-05 | 0 | 0 |
| E/K | 23418 |
Ig-129 |
74 | None | 0.2216 | None | 0.999 | N | 0.681 | 0.441 | 0.466991082792 | gnomAD-4.0.0 | 2.05285E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.47842E-05 | 0 |
| R/S | 23709 |
Ig-130 |
73 | rs1252709285 |
0.3032 | -0.663 | 0.012 | N | 0.461 | 0.098 | 0.151104730317 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| R/S | 23709 |
Ig-130 |
73 | rs1252709285 |
0.3032 | -0.663 | 0.012 | N | 0.461 | 0.098 | 0.151104730317 | gnomAD-4.0.0 | 6.84377E-07 | None | None | None | None | I | None | 2.98864E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 24105 |
Ig-131 |
77 | None | 0.1334 | None | 0.896 | N | 0.439 | 0.367 | 0.481616744073 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/D | 24502 |
Ig-132 |
72 | None | 0.3635 | None | 0.958 | D | 0.475 | 0.333 | 0.328222422547 | gnomAD-4.0.0 | 1.36882E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.52283E-05 | None | 0 | 0 | 8.99628E-07 | 0 | 0 |
| T/I | 24791 |
Ig-133 |
76 | rs1055906361 |
0.112 | None | 0.782 | N | 0.613 | 0.347 | 0.392702134506 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 24791 |
Ig-133 |
76 | rs1055906361 |
0.112 | None | 0.782 | N | 0.613 | 0.347 | 0.392702134506 | gnomAD-4.0.0 | 3.84537E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.18329E-06 | 0 | 0 |
| T/S | 24791 |
Ig-133 |
76 | rs1055906361 |
0.086 | -1.315 | 0.013 | N | 0.278 | 0.158 | 0.226586394389 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| T/S | 24791 |
Ig-133 |
76 | rs1055906361 |
0.086 | -1.315 | 0.013 | N | 0.278 | 0.158 | 0.226586394389 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/S | 24791 |
Ig-133 |
76 | rs1055906361 |
0.086 | -1.315 | 0.013 | N | 0.278 | 0.158 | 0.226586394389 | gnomAD-4.0.0 | 3.84537E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.18329E-06 | 0 | 0 |
| E/K | 25584 |
Ig-135 |
71 | rs1217257725 |
0.2056 | 0.372 | 0.928 | N | 0.634 | 0.347 | 0.394990421082 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| E/K | 25584 |
Ig-135 |
71 | rs1217257725 |
0.2056 | 0.372 | 0.928 | N | 0.634 | 0.347 | 0.394990421082 | gnomAD-4.0.0 | 2.73746E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.56506E-05 | None | 0 | 0 | 8.99616E-07 | 0 | 0 |
| A/G | 25873 |
Ig-136 |
76 | rs751402631 |
0.1416 | -1.325 | 0.027 | N | 0.469 | 0.179 | 0.38342384377 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.7E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/G | 25873 |
Ig-136 |
76 | rs751402631 |
0.1416 | -1.325 | 0.027 | N | 0.469 | 0.179 | 0.38342384377 | gnomAD-4.0.0 | 4.7761E-06 | None | None | None | None | N | None | 0 | 6.86122E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 25873 |
Ig-136 |
76 | rs751402631 |
0.1125 | -0.502 | 0.002 | N | 0.306 | 0.173 | 0.406668915854 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 1.74054E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/V | 25873 |
Ig-136 |
76 | rs751402631 |
0.1125 | -0.502 | 0.002 | N | 0.306 | 0.173 | 0.406668915854 | gnomAD-4.0.0 | 9.55219E-06 | None | None | None | None | N | None | 0 | 1.37224E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 26666 |
Ig-138 |
73 | rs766614271 |
0.3237 | -0.76 | 0.967 | N | 0.729 | 0.543 | 0.507093260865 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.6715E-04 | None | 0 | None | 0 | 0 | 0 |
| E/G | 26666 |
Ig-138 |
73 | rs766614271 |
0.3237 | -0.76 | 0.967 | N | 0.729 | 0.543 | 0.507093260865 | gnomAD-4.0.0 | 3.42129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.25995E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 26955 |
Ig-139 |
76 | rs1336289056 |
0.0693 | -0.709 | 0.273 | N | 0.559 | 0.111 | 0.197625483188 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 26955 |
Ig-139 |
76 | rs1336289056 |
0.0693 | -0.709 | 0.273 | N | 0.559 | 0.111 | 0.197625483188 | gnomAD-4.0.0 | 1.59155E-06 | None | None | None | None | N | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 26955 |
Ig-139 |
76 | rs376947367 |
0.12 | -0.11 | 0.864 | N | 0.722 | 0.566 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/I | 26955 |
Ig-139 |
76 | rs376947367 |
0.12 | -0.11 | 0.864 | N | 0.722 | 0.566 | None | gnomAD-4.0.0 | 1.59157E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85883E-06 | 0 | 0 |
| E/G | 27749 |
Ig-141 |
74 | None | 0.3478 | None | 0.822 | N | 0.68 | 0.506 | 0.522770035047 | gnomAD-4.0.0 | 1.59228E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85914E-06 | 0 | 0 |
| S/L | 28038 |
Ig-142 |
76 | None | 0.1114 | None | 0.698 | D | 0.605 | 0.381 | 0.60194832725 | gnomAD-4.0.0 | 6.84367E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99535E-07 | 0 | 0 |
| K/N | 28433 |
Ig-143 |
76 | rs1444500550 |
0.481 | 0.261 | 0.081 | N | 0.306 | 0.146 | 0.183819452728 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.68105E-04 | None | 0 | None | 0 | 0 | 0 |
| K/N | 28433 |
Ig-143 |
76 | rs1444500550 |
0.481 | 0.261 | 0.081 | N | 0.306 | 0.146 | 0.183819452728 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 28433 |
Ig-143 |
76 | rs1444500550 |
0.481 | 0.261 | 0.081 | N | 0.306 | 0.146 | 0.183819452728 | gnomAD-4.0.0 | 3.1832E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.55988E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Q/E | 28828 |
Ig-144 |
74 | rs1312264246 |
0.0945 | -0.302 | 0.007 | N | 0.203 | 0.161 | 0.18274738541 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Q/E | 28828 |
Ig-144 |
74 | rs1312264246 |
0.0945 | -0.302 | 0.007 | N | 0.203 | 0.161 | 0.18274738541 | gnomAD-4.0.0 | 2.73726E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59821E-06 | 0 | 0 |
| Q/K | 28828 |
Ig-144 |
74 | rs1312264246 |
0.1254 | None | 0.309 | N | 0.407 | 0.216 | 0.197625483188 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Q/K | 28828 |
Ig-144 |
74 | rs1312264246 |
0.1254 | None | 0.309 | N | 0.407 | 0.216 | 0.197625483188 | gnomAD-4.0.0 | 2.73726E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59821E-06 | 0 | 0 |
| Q/R | 28828 |
Ig-144 |
74 | rs1412211195 |
0.127 | None | 0.684 | N | 0.451 | 0.185 | 0.247872288689 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.92678E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 28828 |
Ig-144 |
74 | rs1412211195 |
0.127 | None | 0.684 | N | 0.451 | 0.185 | 0.247872288689 | gnomAD-4.0.0 | 2.5627E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 4.84848E-05 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 29120 |
Ig-145 |
76 | None | 0.1091 | None | 0.505 | N | 0.472 | 0.24 | 0.487772906946 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 30602 |
Ig-149 |
71 | None | 0.4173 | None | 0.998 | N | 0.665 | 0.338 | 0.268660756437 | gnomAD-4.0.0 | 1.59638E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87059E-06 | 0 | 0 |
| E/G | 31291 |
Ig-151 |
74 | rs1471852535 |
0.3293 | -1.149 | 1.0 | N | 0.758 | 0.533 | 0.637385919607 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| E/K | 31291 |
Ig-151 |
74 | None | 0.3271 | None | 0.999 | N | 0.703 | 0.397 | 0.484109215787 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/G | 32088 |
Ig-153 |
72 | None | 0.2588 | None | 0.991 | N | 0.703 | 0.524 | 0.63538471256 | gnomAD-4.0.0 | 1.59153E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77362E-05 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 32088 |
Ig-153 |
72 | rs1351862807 |
0.1328 | 0.08 | 0.969 | D | 0.679 | 0.389 | 0.470730462751 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/K | 32088 |
Ig-153 |
72 | rs1351862807 |
0.1328 | 0.08 | 0.969 | D | 0.679 | 0.389 | 0.470730462751 | gnomAD-4.0.0 | 1.59156E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| K/M | 32382 |
Ig-154 |
76 | rs748057827 |
0.418 | 0.457 | 1.0 | N | 0.679 | 0.62 | 0.482357354261 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| K/M | 32382 |
Ig-154 |
76 | rs748057827 |
0.418 | 0.457 | 1.0 | N | 0.679 | 0.62 | 0.482357354261 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43291E-05 | 0 |
| K/N | 32382 |
Ig-154 |
76 | rs781006271 |
0.6425 | 0.09 | 1.0 | D | 0.773 | 0.328 | 0.268211541103 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| K/N | 32382 |
Ig-154 |
76 | rs781006271 |
0.6425 | 0.09 | 1.0 | D | 0.773 | 0.328 | 0.268211541103 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| K/N | 32382 |
Ig-154 |
76 | rs781006271 |
0.6425 | 0.09 | 1.0 | D | 0.773 | 0.328 | 0.268211541103 | gnomAD-4.0.0 | 6.81677E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.20784E-04 | 0 |
| E/K | 32778 |
Ig-155 |
71 | rs771233778 |
0.5833 | -0.416 | 0.067 | N | 0.328 | 0.264 | 0.245660935333 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/K | 32778 |
Ig-155 |
71 | rs771233778 |
0.5833 | -0.416 | 0.067 | N | 0.328 | 0.264 | 0.245660935333 | gnomAD-4.0.0 | 4.77374E-06 | None | None | None | None | I | None | 0 | 2.28666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
| T/I | 33176 |
Ig-156 |
76 | None | 0.1184 | None | 0.005 | N | 0.165 | 0.187 | 0.486422812247 | gnomAD-4.0.0 | 6.84222E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99465E-07 | 0 | 0 |
| S/I | 33273 |
Ig-157 |
71 | rs774208494 |
0.333 | None | 1.0 | N | 0.778 | 0.501 | 0.866189186955 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07469E-04 | 0 |
| S/I | 33273 |
Ig-157 |
71 | rs774208494 |
0.333 | None | 1.0 | N | 0.778 | 0.501 | 0.866189186955 | gnomAD-4.0.0 | 1.87559E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.37701E-05 | 0 |
| T/I | 33573 |
Ig-158 |
78 | rs2154137156 |
0.472 | None | 1.0 | D | 0.765 | 0.527 | 0.70075097299 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92827E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 33573 |
Ig-158 |
78 | rs2154137156 |
0.472 | None | 1.0 | D | 0.765 | 0.527 | 0.70075097299 | gnomAD-4.0.0 | 1.90449E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.24669E-05 | None | 0 | 0 | 0 | 2.38578E-05 | 0 |
| R/K | 34336 |
Ig-161 |
79 | None | 0.077 | None | None | N | 0.127 | 0.058 | 0.162503812791 | gnomAD-4.0.0 | 1.36832E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79882E-06 | 0 | 0 |
| T/I | 34439 |
Ig-162 |
77 | None | 0.4531 | None | 1.0 | N | 0.816 | 0.568 | 0.660119374745 | gnomAD-4.0.0 | 6.84158E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99405E-07 | 0 | 0 |
| T/S | 34439 |
Ig-162 |
77 | None | 0.2213 | None | 0.999 | N | 0.635 | 0.352 | 0.349870743963 | gnomAD-4.0.0 | 6.84158E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| T/A | 35017 |
Ig-163 |
76 | rs368779151 |
0.1169 | -0.542 | 0.64 | N | 0.509 | 0.154 | 0.241078983079 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.58607E-04 | None | 0 | None | 0 | 0 | 0 |
| T/A | 35017 |
Ig-163 |
76 | rs368779151 |
0.1169 | -0.542 | 0.64 | N | 0.509 | 0.154 | 0.241078983079 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 5.77812E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 35017 |
Ig-163 |
76 | rs368779151 |
0.1169 | -0.542 | 0.64 | N | 0.509 | 0.154 | 0.241078983079 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 2E-03 | 0 | None | None | None | 0 | None |
| T/A | 35017 |
Ig-163 |
76 | rs368779151 |
0.1169 | -0.542 | 0.64 | N | 0.509 | 0.154 | 0.241078983079 | gnomAD-4.0.0 | 8.67418E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.00535E-04 | None | 0 | 0 | 8.47547E-07 | 0 | 6.40184E-05 |
| T/I | 35017 |
Ig-163 |
76 | None | 0.2225 | None | 0.984 | N | 0.602 | 0.519 | 0.433379234345 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| E/D | 35204 |
Ig-164 |
76 | rs1474470920 |
0.4245 | -0.912 | 0.986 | N | 0.533 | 0.172 | 0.391930172978 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| E/D | 35204 |
Ig-164 |
76 | rs1474470920 |
0.4245 | -0.912 | 0.986 | N | 0.533 | 0.172 | 0.391930172978 | gnomAD-4.0.0 | 1.59088E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85745E-06 | 0 | 0 |
| E/Q | 35204 |
Ig-164 |
76 | None | 0.1371 | None | 0.999 | N | 0.698 | 0.234 | 0.442160178816 | gnomAD-4.0.0 | 1.59092E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85749E-06 | 0 | 0 |
| G/R | 35974 |
Ig-169 |
78 | rs372653064 |
0.2102 | -0.287 | 0.81 | N | 0.689 | 0.239 | 0.514015564596 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | -2.196(OBSL1) -1.611(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 2.80978E-04 |
| G/R | 35974 |
Ig-169 |
78 | rs372653064 |
0.2102 | -0.287 | 0.81 | N | 0.689 | 0.239 | 0.514015564596 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | -2.196(OBSL1) -1.611(OBSCN) | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 35974 |
Ig-169 |
78 | rs372653064 |
0.2102 | -0.287 | 0.81 | N | 0.689 | 0.239 | 0.514015564596 | gnomAD-4.0.0 | 6.84188E-07 | None | None | None | -2.196(OBSL1) -1.611(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99431E-07 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.