Structural position:

  • Domain Type: Ig
  • Aligned Position: 161
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand F

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
N/D 84 Ig-1 79 rs1349693054 0.8687 -1.984 0.999 D 0.615 0.615 0.45553875121 gnomAD-2.1.1 3.98E-06 None None None 0.095(TCAP) N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
N/D 84 Ig-1 79 rs1349693054 0.8687 -1.984 0.999 D 0.615 0.615 0.45553875121 gnomAD-4.0.0 1.59045E-06 None None None 0.095(TCAP) N None 0 2.28624E-05 None 0 0 None 0 0 0 0 0
N/K 84 Ig-1 79 rs142851233 0.9865 0.259 1.0 D 0.726 0.545 0.301122078929 gnomAD-2.1.1 3.98E-06 None None None -0.504(TCAP) N None 0 0 None 0 0 None 0 None 0 8.79E-06 0
N/K 84 Ig-1 79 rs142851233 0.9865 0.259 1.0 D 0.726 0.545 0.301122078929 gnomAD-3.1.2 6.57E-06 None None None -0.504(TCAP) N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/K 84 Ig-1 79 rs142851233 0.9865 0.259 1.0 D 0.726 0.545 0.301122078929 gnomAD-4.0.0 6.5722E-06 None None None -0.504(TCAP) N None 0 0 None 0 0 None 0 0 1.47007E-05 0 0
N/S 84 Ig-1 79 rs912344670 0.3145 None 0.999 D 0.583 0.488 0.26169431596 gnomAD-3.1.2 6.57E-06 None None None -0.098(TCAP) N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 84 Ig-1 79 rs912344670 0.3145 None 0.999 D 0.583 0.488 0.26169431596 gnomAD-4.0.0 2.47828E-06 None None None -0.098(TCAP) N None 0 0 None 0 0 None 0 0 3.38981E-06 0 0
N/S 180 Ig-2 77 rs568119356 0.5297 -0.829 0.999 D 0.575 0.642 0.441636318388 gnomAD-2.1.1 2.39E-05 None None None -1.301(TCAP) N None 0 0 None 0 0 None 1.63335E-04 None 0 8.8E-06 0
N/S 180 Ig-2 77 rs568119356 0.5297 -0.829 0.999 D 0.575 0.642 0.441636318388 gnomAD-3.1.2 1.97E-05 None None None -1.301(TCAP) N None 2.41E-05 0 0 0 0 None 0 0 0 4.14079E-04 0
N/S 180 Ig-2 77 rs568119356 0.5297 -0.829 0.999 D 0.575 0.642 0.441636318388 1000 genomes 3.99361E-04 None None None -1.301(TCAP) N None 0 0 None None 0 0 None None None 2E-03 None
N/S 180 Ig-2 77 rs568119356 0.5297 -0.829 0.999 D 0.575 0.642 0.441636318388 gnomAD-4.0.0 1.23903E-05 None None None -1.301(TCAP) N None 1.3323E-05 0 None 0 0 None 0 0 4.2373E-06 1.53708E-04 0
N/H 1160 Ig-4 79 None 0.9825 None 1.0 D 0.721 0.728 0.39162414616 gnomAD-4.0.0 1.59074E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8568E-06 0 0
N/K 1160 Ig-4 79 None 0.999 None 1.0 D 0.703 0.447 0.185906805712 gnomAD-4.0.0 3.18151E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85685E-06 0 3.02188E-05
N/S 1160 Ig-4 79 rs1292982774 0.897 -1.075 0.999 D 0.554 0.595 0.298056030225 gnomAD-2.1.1 7.97E-06 None None None None I None 0 2.89E-05 None 0 0 None 3.27E-05 None 0 0 0
N/S 1160 Ig-4 79 rs1292982774 0.897 -1.075 0.999 D 0.554 0.595 0.298056030225 gnomAD-4.0.0 3.18154E-06 None None None None I None 0 2.28634E-05 None 0 0 None 0 0 0 1.43275E-05 0
N/H 1368 Ig-5 78 rs1377114122 0.959 -0.992 1.0 D 0.732 0.708 0.356897458496 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.84E-06 0
N/H 1368 Ig-5 78 rs1377114122 0.959 -0.992 1.0 D 0.732 0.708 0.356897458496 gnomAD-4.0.0 3.18159E-06 None None None None I None 0 0 None 0 0 None 0 0 5.71389E-06 0 0
N/S 1368 Ig-5 78 rs771563848 0.6115 -0.592 0.999 N 0.583 0.508 0.214338557667 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 0 None 4.62E-05 0 0
N/S 1368 Ig-5 78 rs771563848 0.6115 -0.592 0.999 N 0.583 0.508 0.214338557667 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
N/S 1368 Ig-5 78 rs771563848 0.6115 -0.592 0.999 N 0.583 0.508 0.214338557667 gnomAD-4.0.0 3.84216E-06 None None None None I None 0 0 None 0 0 None 1.56843E-05 0 0 0 5.68473E-05
N/T 1368 Ig-5 78 rs771563848 0.9011 -0.395 0.999 D 0.699 0.683 0.463328977263 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/T 1368 Ig-5 78 rs771563848 0.9011 -0.395 0.999 D 0.699 0.683 0.463328977263 gnomAD-4.0.0 1.5908E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
N/K 1534 Ig-6 78 None 0.9991 None 1.0 D 0.728 0.508 0.395441342475 gnomAD-4.0.0 3.42088E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49677E-06 0 0
N/T 1534 Ig-6 78 None 0.978 None 0.999 D 0.703 0.869 0.774764864444 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/S 1634 Ig-7 79 None 0.5174 None 0.999 D 0.579 0.642 0.277730125212 gnomAD-4.0.0 2.05245E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79864E-06 1.15972E-05 0
N/S 2155 Ig-10 78 None 0.6643 None 0.999 D 0.571 0.681 0.550210968228 gnomAD-4.0.0 3.18128E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71301E-06 0 0
G/E 2342 Ig-12 76 rs2091934798 0.1824 None 0.984 D 0.675 0.457 0.581120218722 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07383E-04 0
G/E 2342 Ig-12 76 rs2091934798 0.1824 None 0.984 D 0.675 0.457 0.581120218722 gnomAD-4.0.0 2.56151E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.68025E-05 0
G/R 2342 Ig-12 76 rs749933813 0.2447 -0.335 1.0 N 0.718 0.557 0.721504376212 gnomAD-2.1.1 1.77E-05 None None None None I None 4.01E-05 2.83E-05 None 0 5.02E-05 None 3.27E-05 None 3.98E-05 0 0
G/R 2342 Ig-12 76 rs749933813 0.2447 -0.335 1.0 N 0.718 0.557 0.721504376212 gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 9.43E-05 0 0 0 0
G/R 2342 Ig-12 76 rs749933813 0.2447 -0.335 1.0 N 0.718 0.557 0.721504376212 gnomAD-4.0.0 4.33722E-06 None None None None I None 1.33522E-05 1.6675E-05 None 0 2.22767E-05 None 1.56191E-05 0 1.69494E-06 1.09779E-05 0
A/S 2431 Ig-13 76 None 0.0631 None None N 0.11 0.067 0.0762999501168 gnomAD-4.0.0 1.36816E-06 None None None None I None 0 0 None 0 0 None 0 0 8.99308E-07 1.15934E-05 0
T/A 2695 Ig-16 75 None 0.0814 None 0.201 N 0.409 0.212 0.143124449307 gnomAD-4.0.0 1.36819E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79861E-06 0 0
T/S 2695 Ig-16 75 rs780082683 0.087 -0.077 0.007 N 0.193 0.161 0.137902524267 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.8E-06 0
T/S 2695 Ig-16 75 rs780082683 0.087 -0.077 0.007 N 0.193 0.161 0.137902524267 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/S 2695 Ig-16 75 rs780082683 0.087 -0.077 0.007 N 0.193 0.161 0.137902524267 gnomAD-4.0.0 1.36307E-05 None None None None N None 0 0 None 0 0 None 0 0 1.77963E-05 0 1.60041E-05
R/S 2783 Ig-17 77 rs374375627 0.3709 -0.217 0.027 N 0.361 0.271 0.213573922156 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 5.45E-05 None 0 None 0 0 0
R/S 2783 Ig-17 77 rs374375627 0.3709 -0.217 0.027 N 0.361 0.271 0.213573922156 gnomAD-4.0.0 1.36815E-06 None None None None N None 2.98686E-05 0 None 0 0 None 0 0 8.99292E-07 0 0
N/D 2957 Ig-19 76 rs138465450 0.2162 None 0.999 N 0.671 0.662 None gnomAD-2.1.1 4.01E-06 None None None None N None 6.16E-05 0 None 0 0 None 0 None 0 0 0
N/D 2957 Ig-19 76 rs138465450 0.2162 None 0.999 N 0.671 0.662 None gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
N/D 2957 Ig-19 76 rs138465450 0.2162 None 0.999 N 0.671 0.662 None gnomAD-4.0.0 5.12543E-06 None None None None N None 5.07614E-05 0 None 0 0 None 0 0 0 0 2.84446E-05
N/S 2957 Ig-19 76 None 0.1266 None 0.999 N 0.653 0.532 0.300449992093 gnomAD-4.0.0 1.59171E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85843E-06 0 0
N/H 3420 Ig-24 76 rs1392369048 0.9082 None 1.0 D 0.734 0.782 0.599777738666 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/H 3420 Ig-24 76 rs1392369048 0.9082 None 1.0 D 0.734 0.782 0.599777738666 gnomAD-4.0.0 6.40374E-06 None None None None N None 0 0 None 0 0 None 0 0 1.19606E-05 0 0
N/S 3543 Ig-25 79 rs777330837 0.4087 -0.882 None None None 0.191 None gnomAD-2.1.1 3.24E-05 None None None None N None 0 2.56717E-04 None 0 0 None 0 None 0 0 0
N/S 3543 Ig-25 79 rs777330837 0.4087 -0.882 None None None 0.191 None gnomAD-3.1.2 1.31E-05 None None None None N None 0 6.55E-05 0 0 0 None 0 0 1.47E-05 0 0
N/S 3543 Ig-25 79 rs777330837 0.4087 -0.882 None None None 0.191 None gnomAD-4.0.0 9.95109E-06 None None None None N None 0 1.67218E-04 None 0 0 None 0 0 5.10402E-06 0 0
N/S 3736 Ig-26 77 rs759184770 0.1283 -0.462 None None None 0.156 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/S 3736 Ig-26 77 rs759184770 0.1283 -0.462 None None None 0.156 None gnomAD-4.0.0 3.42125E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59807E-06 1.15953E-05 0
N/S 3896 Ig-27 77 rs1207560844 0.2363 None 0.999 D 0.555 0.49 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
N/S 3896 Ig-27 77 rs1207560844 0.2363 None 0.999 D 0.555 0.49 None gnomAD-4.0.0 2.47863E-06 None None None None I None 0 1.667E-05 None 0 0 None 0 0 2.54272E-06 0 0
N/D 4776 Ig-30 77 rs727505309 0.812 -1.175 0.999 N 0.599 0.562 0.302459207581 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/D 4776 Ig-30 77 rs727505309 0.812 -1.175 0.999 N 0.599 0.562 0.302459207581 gnomAD-4.0.0 1.36847E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.31873E-05 0
N/K 4776 Ig-30 77 rs952268172 0.9922 None 1.0 N 0.74 0.439 0.191931220699 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/K 4776 Ig-30 77 rs952268172 0.9922 None 1.0 N 0.74 0.439 0.191931220699 gnomAD-4.0.0 6.5716E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47007E-05 0 0
N/S 4776 Ig-30 77 rs369669941 0.372 -0.609 0.999 N 0.563 0.565 None gnomAD-2.1.1 3.18E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
N/S 4776 Ig-30 77 rs369669941 0.372 -0.609 0.999 N 0.563 0.565 None gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 4776 Ig-30 77 rs369669941 0.372 -0.609 0.999 N 0.563 0.565 None gnomAD-4.0.0 9.91508E-06 None None None None I None 2.66909E-05 0 None 0 0 None 0 0 1.18667E-05 0 0
N/K 4871 Ig-31 77 rs1182104962 0.9964 None 1.0 D 0.713 0.588 0.27855597813 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
N/K 4871 Ig-31 77 rs1182104962 0.9964 None 1.0 D 0.713 0.588 0.27855597813 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
N/K 4871 Ig-31 77 rs1182104962 0.9964 None 1.0 D 0.713 0.588 0.27855597813 gnomAD-4.0.0 6.57229E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 4.78469E-04
N/S 5058 Ig-33 78 rs773648136 0.4102 -1.005 0.999 D 0.563 0.546 0.232513804876 gnomAD-2.1.1 8.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
N/S 5058 Ig-33 78 rs773648136 0.4102 -1.005 0.999 D 0.563 0.546 0.232513804876 gnomAD-4.0.0 3.18528E-06 None None None None I None 0 0 None 0 0 None 0 0 5.72338E-06 0 0
N/D 5244 Ig-35 77 rs2080941316 0.9746 None 0.999 D 0.62 0.633 0.402755899245 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.54E-05 0 0 0 None 0 0 0 0 0
N/D 5244 Ig-35 77 rs2080941316 0.9746 None 0.999 D 0.62 0.633 0.402755899245 gnomAD-4.0.0 6.5697E-06 None None None None N None 0 6.54365E-05 None 0 0 None 0 0 0 0 0
N/S 5244 Ig-35 77 rs755749411 0.9145 -0.756 0.999 D 0.585 0.621 0.277317399466 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 9.96E-05 0 None 0 None 0 0 0
N/S 5244 Ig-35 77 rs755749411 0.9145 -0.756 0.999 D 0.585 0.621 0.277317399466 gnomAD-4.0.0 1.36932E-06 None None None None N None 0 0 None 7.65521E-05 0 None 0 0 0 0 0
N/S 5337 Ig-36 77 rs752924679 0.4502 -0.699 0.999 N 0.589 0.598 None gnomAD-2.1.1 6.47E-05 None None None None N None 4.13E-05 2.83E-05 None 0 0 None 1.64355E-04 None 0 8.68E-05 0
N/S 5337 Ig-36 77 rs752924679 0.4502 -0.699 0.999 N 0.589 0.598 None gnomAD-3.1.2 3.94E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 7.35E-05 0 0
N/S 5337 Ig-36 77 rs752924679 0.4502 -0.699 0.999 N 0.589 0.598 None gnomAD-4.0.0 7.2581E-05 None None None None N None 1.0682E-04 1.66811E-05 None 0 4.45991E-05 None 0 0 7.63635E-05 7.69874E-05 1.4424E-04
N/D 5433 Ig-37 77 rs749623638 0.9554 -1.882 0.999 D 0.591 0.544 0.336155897331 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 4.66E-05 0 0
N/D 5433 Ig-37 77 rs749623638 0.9554 -1.882 0.999 D 0.591 0.544 0.336155897331 gnomAD-4.0.0 6.00161E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 7.32654E-05
N/D 5526 Ig-38 77 rs752558197 0.9253 None 0.999 D 0.603 0.565 None gnomAD-4.0.0 3.42267E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49886E-06 0 0
N/H 5526 Ig-38 77 rs752558197 0.9209 -1.277 1.0 N 0.733 0.631 0.438170831126 gnomAD-2.1.1 2.01E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.56E-05 1.665E-04
N/H 5526 Ig-38 77 rs752558197 0.9209 -1.277 1.0 N 0.733 0.631 0.438170831126 gnomAD-4.0.0 3.42267E-05 None None None None N None 0 0 None 0 0 None 0 0 4.31891E-05 0 3.31532E-05
N/S 5526 Ig-38 77 rs767376352 0.4239 -0.845 0.999 N 0.573 0.533 0.316198179892 gnomAD-2.1.1 8.06E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 8.9E-06 0
N/S 5526 Ig-38 77 rs767376352 0.4239 -0.845 0.999 N 0.573 0.533 0.316198179892 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 6.55E-05 0 0 0 None 0 0 0 0 0
N/S 5526 Ig-38 77 rs767376352 0.4239 -0.845 0.999 N 0.573 0.533 0.316198179892 gnomAD-4.0.0 6.41093E-06 None None None None N None 3.3849E-05 1.69641E-05 None 0 0 None 1.56868E-05 0 2.39515E-06 0 0
N/S 5620 Ig-39 78 rs747660270 0.5834 -0.776 0.287 N 0.248 0.339 0.233150807113 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
N/S 5620 Ig-39 78 rs747660270 0.5834 -0.776 0.287 N 0.248 0.339 0.233150807113 gnomAD-4.0.0 1.5932E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86272E-06 0 0
N/S 5713 Ig-40 77 rs374597389 0.5145 None 0.001 N 0.302 0.323 0.126345400529 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/S 5713 Ig-40 77 rs374597389 0.5145 None 0.001 N 0.302 0.323 0.126345400529 gnomAD-4.0.0 2.0299E-06 None None None None I None 3.49455E-05 0 None 0 0 None 0 0 0 0 0
N/K 5806 Ig-41 77 rs990308126 0.9987 None 1.0 D 0.742 0.497 0.247872288689 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
N/K 5806 Ig-41 77 rs990308126 0.9987 None 1.0 D 0.742 0.497 0.247872288689 gnomAD-4.0.0 7.68732E-06 None None None None I None 0 1.69509E-05 None 0 0 None 0 0 7.1794E-06 0 5.68861E-05
N/S 5806 Ig-41 77 None 0.9144 None 0.999 N 0.594 0.524 0.325263233342 gnomAD-4.0.0 4.1054E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39692E-06 0 0
N/K 6088 Ig-44 77 rs748182054 0.9968 -0.088 1.0 D 0.744 0.515 0.227260227426 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 3.44828E-03 0 None 0 None 0 0 0
N/S 6275 Ig-46 77 rs184412722 0.2821 -0.92 0.362 N 0.306 0.286 None gnomAD-2.1.1 3.51379E-03 None None None None I None 2.06919E-04 7.65263E-04 None 1.06775E-03 1.02575E-04 None 2.2327E-02 None 4.01E-05 1.81387E-03 3.10209E-03
N/S 6275 Ig-46 77 rs184412722 0.2821 -0.92 0.362 N 0.306 0.286 None gnomAD-3.1.2 1.8139E-03 None None None None I None 2.41255E-04 1.83366E-03 0 8.64553E-04 0 None 9.42E-05 0 1.69063E-03 2.37997E-02 1.91022E-03
N/S 6275 Ig-46 77 rs184412722 0.2821 -0.92 0.362 N 0.306 0.286 None 1000 genomes 5.99042E-03 None None None None I None 0 1.4E-03 None None 0 3E-03 None None None 2.66E-02 None
N/S 6275 Ig-46 77 rs184412722 0.2821 -0.92 0.362 N 0.306 0.286 None gnomAD-4.0.0 2.22775E-03 None None None None I None 3.19974E-04 1.00047E-03 None 8.45451E-04 1.56138E-04 None 7.81274E-05 3.96825E-03 1.10259E-03 2.15868E-02 2.93091E-03
N/S 6368 Ig-47 77 rs748146062 0.8112 -0.828 0.999 N 0.587 0.536 0.350964488264 gnomAD-2.1.1 1.22E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.69E-05 0
N/S 6368 Ig-47 77 rs748146062 0.8112 -0.828 0.999 N 0.587 0.536 0.350964488264 gnomAD-4.0.0 4.79001E-06 None None None None N None 0 0 None 0 0 None 0 0 8.60003E-06 0 0
N/K 6461 Ig-48 77 rs76771282 0.9988 -0.197 1.0 D 0.755 0.527 0.289847578895 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.61E-05 None 0 None 0 0 0
N/K 6461 Ig-48 77 rs76771282 0.9988 -0.197 1.0 D 0.755 0.527 0.289847578895 gnomAD-4.0.0 6.84733E-07 None None None None N None 0 0 None 0 2.52704E-05 None 0 0 0 0 0
N/S 6557 Ig-49 77 rs764245160 0.469 -0.839 0.999 N 0.589 0.544 None gnomAD-2.1.1 4.1E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.05E-06 0
N/S 6557 Ig-49 77 rs764245160 0.469 -0.839 0.999 N 0.589 0.544 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 6557 Ig-49 77 rs764245160 0.469 -0.839 0.999 N 0.589 0.544 None gnomAD-4.0.0 6.45303E-06 None None None None I None 0 0 None 0 0 None 0 0 1.2061E-05 0 0
N/S 6650 Ig-50 77 rs751222632 0.4457 -1.14 0.999 N 0.562 0.593 0.294206760003 gnomAD-2.1.1 1.11E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.61E-05 1.468E-04
N/S 6650 Ig-50 77 rs751222632 0.4457 -1.14 0.999 N 0.562 0.593 0.294206760003 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 4.78011E-04
N/S 6650 Ig-50 77 rs751222632 0.4457 -1.14 0.999 N 0.562 0.593 0.294206760003 gnomAD-4.0.0 6.52387E-06 None None None None N None 1.7118E-05 0 None 0 0 None 0 0 7.2926E-06 0 2.89184E-05
N/T 6650 Ig-50 77 rs751222632 0.8778 -0.778 1.0 D 0.708 0.7 0.558889990735 gnomAD-2.1.1 4.21E-06 None None None None N None 0 3.13E-05 None 0 0 None 0 None 0 0 0
N/T 6650 Ig-50 77 rs751222632 0.8778 -0.778 1.0 D 0.708 0.7 0.558889990735 gnomAD-4.0.0 1.62767E-06 None None None None N None 0 2.41709E-05 None 0 0 None 0 0 0 0 0
N/K 6837 Ig-52 77 None 0.9976 None 1.0 D 0.743 0.669 0.40528724903 gnomAD-4.0.0 1.59745E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87071E-06 0 0
N/S 6931 Ig-53 78 rs200866883 0.8328 -1.128 0.999 D 0.561 0.625 None gnomAD-2.1.1 2.19215E-04 None None None None N None 8.33E-05 5.75E-05 None 0 0 None 0 None 0 4.39986E-04 1.44217E-04
N/S 6931 Ig-53 78 rs200866883 0.8328 -1.128 0.999 D 0.561 0.625 None gnomAD-3.1.2 2.49668E-04 None None None None N None 1.20575E-04 6.55E-05 0 0 0 None 0 0 4.70395E-04 0 0
N/S 6931 Ig-53 78 rs200866883 0.8328 -1.128 0.999 D 0.561 0.625 None 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
N/S 6931 Ig-53 78 rs200866883 0.8328 -1.128 0.999 D 0.561 0.625 None gnomAD-4.0.0 3.38553E-04 None None None None N None 1.2009E-04 5.03542E-05 None 0 0 None 0 0 4.34573E-04 0 3.37729E-04
N/S 7024 Ig-54 77 None 0.8999 None 0.999 N 0.575 0.415 None gnomAD-4.0.0 1.5921E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85959E-06 0 0
N/D 7120 Ig-55 77 rs764627613 0.9276 -0.885 0.996 D 0.573 0.534 0.436239592564 gnomAD-2.1.1 1.43E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.13E-05 0
N/D 7120 Ig-55 77 rs764627613 0.9276 -0.885 0.996 D 0.573 0.534 0.436239592564 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
N/D 7120 Ig-55 77 rs764627613 0.9276 -0.885 0.996 D 0.573 0.534 0.436239592564 gnomAD-4.0.0 1.98365E-05 None None None None I None 0 0 None 0 0 None 0 0 2.54361E-05 0 3.20318E-05
N/T 7120 Ig-55 77 rs192344560 0.8457 -0.505 0.992 D 0.607 0.608 None gnomAD-2.1.1 1.43E-05 None None None None I None 0 0 None 0 2.05044E-04 None 0 None 0 0 0
N/T 7120 Ig-55 77 rs192344560 0.8457 -0.505 0.992 D 0.607 0.608 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 1.9253E-04 None 0 0 0 0 0
N/T 7120 Ig-55 77 rs192344560 0.8457 -0.505 0.992 D 0.607 0.608 None 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 1E-03 0 None None None 0 None
N/T 7120 Ig-55 77 rs192344560 0.8457 -0.505 0.992 D 0.607 0.608 None gnomAD-4.0.0 2.56345E-06 None None None None I None 0 0 None 0 4.8506E-05 None 0 0 0 0 0
N/K 7213 Ig-56 77 rs562167496 0.9875 -0.357 1.0 D 0.742 0.403 0.183819452728 gnomAD-2.1.1 8.07E-06 None None None None N None 1.2945E-04 0 None 0 0 None 0 None 0 0 0
N/K 7213 Ig-56 77 rs562167496 0.9875 -0.357 1.0 D 0.742 0.403 0.183819452728 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/K 7213 Ig-56 77 rs562167496 0.9875 -0.357 1.0 D 0.742 0.403 0.183819452728 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
N/K 7213 Ig-56 77 rs562167496 0.9875 -0.357 1.0 D 0.742 0.403 0.183819452728 gnomAD-4.0.0 1.85958E-06 None None None None N None 2.66581E-05 0 None 0 0 None 0 0 0 0 1.60159E-05
N/T 7213 Ig-56 77 rs794729623 0.7533 None 0.999 D 0.713 0.666 0.401185642668 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/T 7213 Ig-56 77 rs794729623 0.7533 None 0.999 D 0.713 0.666 0.401185642668 gnomAD-4.0.0 4.33919E-06 None None None None N None 4.00481E-05 0 None 0 0 None 0 0 2.54323E-06 0 1.60195E-05
N/Y 7306 Ig-57 77 rs773636793 0.9787 -0.628 1.0 D 0.753 0.672 None gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
N/Y 7306 Ig-57 77 rs773636793 0.9787 -0.628 1.0 D 0.753 0.672 None gnomAD-3.1.2 2.63E-05 None None None None N None 9.65E-05 0 0 0 0 None 0 0 0 0 0
N/Y 7306 Ig-57 77 rs773636793 0.9787 -0.628 1.0 D 0.753 0.672 None gnomAD-4.0.0 6.40695E-06 None None None None N None 8.45966E-05 0 None 0 0 None 0 0 0 0 0
N/S 7591 Ig-60 77 rs368750726 0.3938 -0.656 0.999 N 0.587 0.568 0.29132392195 gnomAD-2.1.1 8.06E-06 None None None None I None 0 0 None 0 0 None 6.56E-05 None 0 0 0
N/S 7591 Ig-60 77 rs368750726 0.3938 -0.656 0.999 N 0.587 0.568 0.29132392195 gnomAD-3.1.2 1.97E-05 None None None None I None 4.82E-05 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 7591 Ig-60 77 rs368750726 0.3938 -0.656 0.999 N 0.587 0.568 0.29132392195 gnomAD-4.0.0 1.2399E-05 None None None None I None 8.01004E-05 0 None 0 0 None 0 0 9.32682E-06 2.19945E-05 1.6019E-05
N/T 7591 Ig-60 77 rs368750726 0.8516 -0.419 1.0 N 0.705 0.702 None gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
N/D 7685 Ig-61 78 None 0.9398 None 0.996 D 0.601 0.596 0.492267288202 gnomAD-4.0.0 1.37507E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80841E-06 0 0
N/S 7685 Ig-61 78 None 0.3438 None 0.996 N 0.567 0.502 0.366848117066 gnomAD-4.0.0 1.60947E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43972E-05 0
N/D 7778 Ig-62 77 rs2078170998 0.98 None 0.966 D 0.609 0.427 0.294918367191 gnomAD-4.0.0 3.18347E-06 None None None None I None 0 0 None 0 5.54631E-05 None 0 0 0 0 0
N/S 7778 Ig-62 77 None 0.6786 None 0.905 N 0.56 0.484 0.219573609325 gnomAD-4.0.0 1.59179E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43349E-05 0
N/H 7872 Ig-63 78 None 0.9904 None 1.0 D 0.692 0.58 0.494433119893 gnomAD-4.0.0 1.59291E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86138E-06 0 0
N/K 7872 Ig-63 78 rs181206334 0.9991 -0.429 1.0 D 0.649 0.523 0.112648838833 gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.79E-05 0
N/K 7872 Ig-63 78 rs181206334 0.9991 -0.429 1.0 D 0.649 0.523 0.112648838833 gnomAD-4.0.0 1.02683E-05 None None None None I None 0 0 None 0 0 None 0 0 1.34971E-05 0 0
N/S 7872 Ig-63 78 rs746024262 0.9205 -1.038 0.995 N 0.56 0.61 0.366085729538 gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 5.59E-05 None 3.27E-05 None 0 0 0
N/S 7872 Ig-63 78 rs746024262 0.9205 -1.038 0.995 N 0.56 0.61 0.366085729538 gnomAD-4.0.0 1.36909E-06 None None None None I None 0 0 None 0 2.5222E-05 None 0 0 0 1.16004E-05 0
N/T 7872 Ig-63 78 rs746024262 0.971 -0.722 0.993 D 0.604 0.593 0.49179695788 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/T 7872 Ig-63 78 rs746024262 0.971 -0.722 0.993 D 0.604 0.593 0.49179695788 gnomAD-4.0.0 3.42274E-06 None None None None I None 0 0 None 0 0 None 0 0 0 4.64016E-05 1.65777E-05
N/D 7965 Ig-64 77 None 0.9606 None 0.999 D 0.603 0.589 0.407357902709 gnomAD-4.0.0 3.42398E-06 None None None None N None 0 0 None 0 0 None 0 0 4.50175E-06 0 0
N/K 7965 Ig-64 77 rs1363515138 0.9981 None 1.0 D 0.733 0.483 0.240491677333 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
N/K 7965 Ig-64 77 rs1363515138 0.9981 None 1.0 D 0.733 0.483 0.240491677333 gnomAD-4.0.0 1.3146E-05 None None None None N None 0 0 None 0 0 None 0 0 2.94048E-05 0 0
N/D 8061 Ig-65 77 None 0.9023 None 0.999 D 0.635 0.558 0.416833835346 gnomAD-4.0.0 1.59138E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8586E-06 0 0
N/K 8061 Ig-65 77 rs1376169033 0.9936 None 1.0 D 0.745 0.39 0.137902524267 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/K 8061 Ig-65 77 rs1376169033 0.9936 None 1.0 D 0.745 0.39 0.137902524267 gnomAD-4.0.0 6.57341E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47024E-05 0 0
N/S 8061 Ig-65 77 rs752499533 0.3698 -0.65 0.999 N 0.599 0.527 0.278968121808 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 0 None 9.81E-05 None 0 8.94E-06 0
N/S 8061 Ig-65 77 rs752499533 0.3698 -0.65 0.999 N 0.599 0.527 0.278968121808 gnomAD-3.1.2 6.57E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
N/S 8061 Ig-65 77 rs752499533 0.3698 -0.65 0.999 N 0.599 0.527 0.278968121808 gnomAD-4.0.0 4.33808E-06 None None None None I None 0 1.66683E-05 None 0 0 None 0 0 8.47637E-07 5.49089E-05 0
N/D 8154 Ig-66 77 rs757293293 0.883 -1.492 0.999 D 0.605 0.623 0.361958692863 gnomAD-2.1.1 8.04E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
N/D 8154 Ig-66 77 rs757293293 0.883 -1.492 0.999 D 0.605 0.623 0.361958692863 gnomAD-4.0.0 3.18254E-06 None None None None N None 0 4.57247E-05 None 0 0 None 0 0 0 0 0
N/S 8154 Ig-66 77 rs749455191 0.3215 -1.209 0.999 N 0.571 0.621 0.258283824007 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/S 8154 Ig-66 77 rs749455191 0.3215 -1.209 0.999 N 0.571 0.621 0.258283824007 gnomAD-4.0.0 2.73685E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.6379E-05 0
N/S 8247 Ig-67 77 rs1423015364 0.8166 None 0.994 N 0.565 0.525 0.298745278005 gnomAD-4.0.0 3.18289E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71729E-06 0 0
N/S 8340 Ig-68 77 None 0.7637 None 1.0 D 0.576 0.7 0.483596354421 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
N/T 8436 Ig-69 77 None 0.8795 None 1.0 N 0.707 0.605 0.328486982098 gnomAD-4.0.0 1.20033E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
N/S 8532 Ig-70 77 rs368106359 0.3379 -0.945 0.999 N 0.592 0.616 None gnomAD-2.1.1 1.21E-05 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 8.89E-06 1.66334E-04
N/S 8532 Ig-70 77 rs368106359 0.3379 -0.945 0.999 N 0.592 0.616 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 8532 Ig-70 77 rs368106359 0.3379 -0.945 0.999 N 0.592 0.616 None gnomAD-4.0.0 8.05777E-06 None None None None I None 0 1.66722E-05 None 0 0 None 0 0 1.01734E-05 0 0
N/D 8626 Ig-71 78 rs2077357318 0.9505 None 0.996 D 0.624 0.576 0.377274123778 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/D 8626 Ig-71 78 rs2077357318 0.9505 None 0.996 D 0.624 0.576 0.377274123778 gnomAD-4.0.0 6.57177E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47003E-05 0 0
N/S 8626 Ig-71 78 rs200355367 0.4105 -0.897 0.996 N 0.591 0.485 None gnomAD-2.1.1 1.21503E-04 None None None None N None 4.13E-05 0 None 0 0 None 0 None 0 2.5826E-04 0
N/S 8626 Ig-71 78 rs200355367 0.4105 -0.897 0.996 N 0.591 0.485 None gnomAD-3.1.2 1.70882E-04 None None None None N None 2.41E-05 0 0 0 1.9253E-04 None 0 0 3.23463E-04 2.07641E-04 4.77555E-04
N/S 8626 Ig-71 78 rs200355367 0.4105 -0.897 0.996 N 0.591 0.485 None gnomAD-4.0.0 3.26633E-04 None None None None N None 4.00588E-05 0 None 0 6.6839E-05 None 0 0 4.17945E-04 4.39261E-05 3.84418E-04
N/D 8719 Ig-72 77 rs770551201 0.9024 -1.16 0.879 D 0.58 0.49 0.263140351381 gnomAD-2.1.1 8.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
N/D 8719 Ig-72 77 rs770551201 0.9024 -1.16 0.879 D 0.58 0.49 0.263140351381 gnomAD-4.0.0 2.05336E-06 None None None None I None 0 0 None 0 0 None 0 0 2.6992E-06 0 0
N/S 8813 Ig-73 78 rs2077136991 0.5983 None 0.999 N 0.561 0.622 0.372446077551 gnomAD-4.0.0 1.5916E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85915E-06 0 0
N/K 8906 Ig-74 77 rs776901808 0.9947 -0.497 1.0 D 0.709 0.486 0.195762928549 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
N/K 8906 Ig-74 77 rs776901808 0.9947 -0.497 1.0 D 0.709 0.486 0.195762928549 gnomAD-4.0.0 1.36856E-06 None None None None N None 0 2.23714E-05 None 0 0 None 0 0 0 1.15958E-05 0
N/S 8906 Ig-74 77 None 0.6887 None 0.999 N 0.563 0.543 0.260249123532 gnomAD-4.0.0 1.59162E-06 None None None None N None 0 0 None 4.76735E-05 0 None 0 0 0 0 0
N/D 9095 Ig-76 77 None 0.8665 None 0.999 D 0.614 0.56 0.287603790349 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/S 9095 Ig-76 77 rs1319823465 0.2821 -1.028 0.999 N 0.577 0.51 0.215109475489 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
N/K 9188 Ig-77 77 None 0.9957 None 0.996 D 0.645 0.502 0.18274738541 gnomAD-4.0.0 6.84217E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99465E-07 0 0
N/Y 9188 Ig-77 77 None 0.9741 None 1.0 D 0.787 0.695 0.752086344402 gnomAD-4.0.0 1.59129E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43324E-05 0
N/K 9377 Ig-79 77 rs72648997 0.9969 -0.397 1.0 None 0.738 0.553 0.251639045875 gnomAD-2.1.1 2.02E-05 None None None None N None 3.23123E-04 0 None 0 0 None 0 None 0 0 0
N/K 9377 Ig-79 77 rs72648997 0.9969 -0.397 1.0 None 0.738 0.553 0.251639045875 gnomAD-3.1.2 1.97E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
N/K 9377 Ig-79 77 rs72648997 0.9969 -0.397 1.0 None 0.738 0.553 0.251639045875 gnomAD-4.0.0 4.95891E-06 None None None None N None 1.06775E-04 0 None 0 0 None 0 0 0 0 0
N/S 9377 Ig-79 77 None 0.4739 None 0.999 None 0.603 0.585 0.286465849087 gnomAD-4.0.0 1.59238E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43493E-05 0
N/H 9473 Ig-80 77 None 0.9421 None 1.0 None 0.721 0.634 0.398133443147 gnomAD-4.0.0 3.18585E-06 None None None None I None 0 0 None 0 0 None 0 0 5.7171E-06 0 0
N/S 9473 Ig-80 77 rs2076526398 0.4165 None 0.999 None 0.582 0.553 0.262175524916 gnomAD-4.0.0 1.59291E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43345E-05 0
N/D 9570 Ig-81 78 rs748118078 0.9307 -2.035 0.999 None 0.637 0.621 0.380394304726 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
N/D 9570 Ig-81 78 rs748118078 0.9307 -2.035 0.999 None 0.637 0.621 0.380394304726 gnomAD-4.0.0 1.59131E-06 None None None None I None 0 0 None 0 0 None 1.8826E-05 0 0 0 0
N/S 9570 Ig-81 78 rs727503641 0.4202 -0.195 0.999 None 0.599 0.557 0.30212335484 gnomAD-2.1.1 8.04E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 8.87E-06 0
N/S 9570 Ig-81 78 rs727503641 0.4202 -0.195 0.999 None 0.599 0.557 0.30212335484 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
N/S 9570 Ig-81 78 rs727503641 0.4202 -0.195 0.999 None 0.599 0.557 0.30212335484 gnomAD-4.0.0 1.30131E-05 None None None None I None 1.33454E-05 1.66667E-05 None 0 0 None 0 0 1.18667E-05 5.48908E-05 0
N/K 9666 Ig-82 77 None 0.9982 None 1.0 None 0.723 0.463 0.132336055621 gnomAD-4.0.0 1.5914E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43312E-05 0
N/S 9666 Ig-82 77 None 0.5241 None 0.999 None 0.58 0.417 0.185906805712 gnomAD-4.0.0 3.18275E-06 None None None None I None 0 0 None 4.76872E-05 0 None 0 0 2.85834E-06 0 0
D/Y 10064 Ig-85 76 None 0.227 None 0.427 None 0.492 0.185 0.373357554552 gnomAD-4.0.0 1.36833E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79881E-06 0 0
E/G 10154 Ig-86 77 rs761055099 0.643 -0.628 1.0 None 0.641 0.4 0.260249123532 gnomAD-2.1.1 4.01E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.85E-06 0
E/G 10154 Ig-86 77 rs761055099 0.643 -0.628 1.0 None 0.641 0.4 0.260249123532 gnomAD-4.0.0 1.59085E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85745E-06 0 0
L/V 13762 Ig-87 79 None 0.4516 None 0.998 N 0.468 0.188 0.158396225186 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/K 13856 Ig-88 77 rs559906667 0.7509 None 0.82 N 0.254 0.267 0.0138822411134 gnomAD-4.0.0 2.743E-06 None None None None N None 8.9858E-05 0 None 0 0 None 0 0 0 1.16339E-05 0
N/S 13856 Ig-88 77 rs369638798 0.2866 -0.449 0.023 N 0.179 0.146 None gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
N/S 13856 Ig-88 77 rs369638798 0.2866 -0.449 0.023 N 0.179 0.146 None gnomAD-4.0.0 1.59917E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87606E-06 0 0
N/Y 14040 Ig-90 76 rs2154228320 0.8415 None 1.0 D 0.723 0.584 0.578910049572 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
N/Y 14040 Ig-90 76 rs2154228320 0.8415 None 1.0 D 0.723 0.584 0.578910049572 gnomAD-4.0.0 6.57056E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.07383E-04 0
G/A 14128 Ig-91 75 rs370793851 0.3943 -0.381 0.984 N 0.619 0.408 None gnomAD-2.1.1 5.3E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.07916E-04 1.67785E-04
G/A 14128 Ig-91 75 rs370793851 0.3943 -0.381 0.984 N 0.619 0.408 None gnomAD-3.1.2 3.95E-05 None None None None N None 0 0 0 0 0 None 0 0 8.83E-05 0 0
G/A 14128 Ig-91 75 rs370793851 0.3943 -0.381 0.984 N 0.619 0.408 None gnomAD-4.0.0 8.81726E-05 None None None None N None 1.34045E-05 0 None 0 0 None 0 0 1.03483E-04 0 3.04966E-04
E/K 14217 Ig-92 76 rs727503629 0.1681 0.514 0.012 N 0.311 0.088 0.191931220699 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
E/K 14217 Ig-92 76 rs727503629 0.1681 0.514 0.012 N 0.311 0.088 0.191931220699 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
E/K 14217 Ig-92 76 rs727503629 0.1681 0.514 0.012 N 0.311 0.088 0.191931220699 gnomAD-4.0.0 1.85961E-06 None None None None N None 4.00652E-05 0 None 0 0 None 0 0 0 0 0
T/I 14305 Ig-93 75 None 0.3635 None 1.0 D 0.735 0.475 0.640098834198 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
N/T 14394 Ig-94 76 rs1264004420 0.4309 0.066 0.997 N 0.709 0.452 0.323886383625 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 9.97E-05 0 None 0 None 0 0 0
N/T 14394 Ig-94 76 rs1264004420 0.4309 0.066 0.997 N 0.709 0.452 0.323886383625 gnomAD-4.0.0 1.59282E-06 None None None None N None 0 0 None 4.77145E-05 0 None 0 0 0 0 0
D/E 14483 Ig-95 76 rs765321685 0.3217 -0.09 1.0 D 0.588 0.588 0.39843156188 gnomAD-2.1.1 1.79E-05 None None None None I None 0 2.83E-05 None 0 0 None 0 None 0 3.14E-05 0
D/E 14483 Ig-95 76 rs765321685 0.3217 -0.09 1.0 D 0.588 0.588 0.39843156188 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
D/E 14483 Ig-95 76 rs765321685 0.3217 -0.09 1.0 D 0.588 0.588 0.39843156188 gnomAD-4.0.0 8.97284E-06 None None None None I None 0 1.69578E-05 None 0 0 None 0 0 1.43658E-05 0 0
D/H 14483 Ig-95 76 rs750442099 0.603 -0.213 1.0 D 0.689 0.516 0.620859307327 gnomAD-2.1.1 8.06E-06 None None None None I None 0 0 None 0 0 None 0 None 4.64E-05 8.92E-06 0
D/H 14483 Ig-95 76 rs750442099 0.603 -0.213 1.0 D 0.689 0.516 0.620859307327 gnomAD-4.0.0 3.18471E-06 None None None None I None 0 0 None 0 0 None 3.76563E-05 0 0 0 0
G/W 14572 Ig-96 76 None 0.6726 None 0.998 D 0.707 0.578 0.821373730238 gnomAD-4.0.0 1.60464E-06 None None None None I None 0 0 None 0 0 None 1.89236E-05 0 0 0 0
T/I 14661 Ig-97 76 rs370339661 0.3548 -0.02 0.997 N 0.505 0.425 None gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
T/I 14661 Ig-97 76 rs370339661 0.3548 -0.02 0.997 N 0.505 0.425 None gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/I 14661 Ig-97 76 rs370339661 0.3548 -0.02 0.997 N 0.505 0.425 None gnomAD-4.0.0 6.57626E-06 None None None None N None 2.41371E-05 0 None 0 0 None 0 0 0 0 0
N/H 14750 Ig-98 76 rs1299201088 0.2442 -0.288 0.999 D 0.789 0.584 0.279370189704 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
N/H 14750 Ig-98 76 rs1299201088 0.2442 -0.288 0.999 D 0.789 0.584 0.279370189704 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
N/H 14750 Ig-98 76 rs1299201088 0.2442 -0.288 0.999 D 0.789 0.584 0.279370189704 gnomAD-4.0.0 1.31496E-05 None None None None N None 4.82486E-05 0 None 0 0 None 0 0 0 0 0
N/S 14750 Ig-98 76 rs767633080 0.1234 0.284 0.997 N 0.619 0.448 0.194818534648 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 8.89E-06 0
N/S 14750 Ig-98 76 rs767633080 0.1234 0.284 0.997 N 0.619 0.448 0.194818534648 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 14750 Ig-98 76 rs767633080 0.1234 0.284 0.997 N 0.619 0.448 0.194818534648 gnomAD-4.0.0 5.57919E-06 None None None None N None 1.33529E-05 0 None 0 4.46768E-05 None 0 1.64582E-04 4.23919E-06 0 0
N/Y 14750 Ig-98 76 None 0.4116 None 1.0 D 0.753 0.61 0.618843267604 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/N 14839 Ig-99 75 rs753336110 0.2354 -0.261 1.0 N 0.53 0.347 0.165133752707 gnomAD-2.1.1 4.09E-06 None None None None N None 0 0 None 0 0 None 3.36E-05 None 0 0 0
D/N 14839 Ig-99 75 rs753336110 0.2354 -0.261 1.0 N 0.53 0.347 0.165133752707 gnomAD-4.0.0 6.86916E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.1708E-05 0
D/N 14928 Ig-100 76 rs772700762 0.1601 -0.243 0.961 N 0.36 0.211 0.183819452728 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
D/N 14928 Ig-100 76 rs772700762 0.1601 -0.243 0.961 N 0.36 0.211 0.183819452728 gnomAD-4.0.0 1.59389E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86351E-06 0 0
D/V 14928 Ig-100 76 rs2058743726 0.4314 None 0.994 N 0.58 0.252 0.218845423259 gnomAD-4.0.0 6.84692E-07 None None None None N None 2.99509E-05 0 None 0 0 None 0 0 0 0 0
T/I 15017 Ig-101 76 None 0.38 None 0.938 D 0.399 0.352 0.469742815239 gnomAD-4.0.0 6.84868E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00045E-07 0 0
T/R 15017 Ig-101 76 rs777613831 0.2596 0.063 0.984 N 0.377 0.38 None gnomAD-2.1.1 4.04E-06 None None None None N None 6.48E-05 0 None 0 0 None 0 None 0 0 0
T/R 15017 Ig-101 76 rs777613831 0.2596 0.063 0.984 N 0.377 0.38 None gnomAD-3.1.2 1.97E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
T/R 15017 Ig-101 76 rs777613831 0.2596 0.063 0.984 N 0.377 0.38 None gnomAD-4.0.0 3.10159E-06 None None None None N None 5.34645E-05 0 None 0 0 None 0 0 8.48182E-07 0 0
S/G 15106 Ig-102 76 None 0.0877 None 0.002 D 0.105 0.407 0.246215685461 gnomAD-4.0.0 1.59412E-06 None None None None N None 0 2.29221E-05 None 0 0 None 0 0 0 0 0
S/R 15106 Ig-102 76 rs756694133 0.5488 0.041 0.642 D 0.468 0.521 0.384419519794 gnomAD-2.1.1 8.07E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
S/R 15106 Ig-102 76 rs756694133 0.5488 0.041 0.642 D 0.468 0.521 0.384419519794 gnomAD-4.0.0 4.78231E-06 None None None None N None 0 0 None 0 0 None 0 0 8.58939E-06 0 0
S/T 15106 Ig-102 76 None 0.083 None 0.01 D 0.097 0.363 0.210429274316 gnomAD-4.0.0 1.59412E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86318E-06 0 0
A/T 15195 Ig-103 76 rs536167152 0.0947 -0.432 0.007 N 0.063 0.043 0.170165803431 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 15195 Ig-103 76 rs536167152 0.0947 -0.432 0.007 N 0.063 0.043 0.170165803431 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
A/T 15195 Ig-103 76 rs536167152 0.0947 -0.432 0.007 N 0.063 0.043 0.170165803431 gnomAD-4.0.0 6.57791E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47288E-05 0 0
N/H 15283 Ig-104 76 rs992729815 0.8978 None 1.0 D 0.719 0.693 0.339793275041 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/H 15283 Ig-104 76 rs992729815 0.8978 None 1.0 D 0.719 0.693 0.339793275041 gnomAD-4.0.0 2.03025E-06 None None None None N None 0 0 None 0 0 None 0 0 2.41012E-06 0 0
N/S 15283 Ig-104 76 rs1326395034 0.39 -0.789 0.999 D 0.587 0.424 None gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
N/S 15283 Ig-104 76 rs1326395034 0.39 -0.789 0.999 D 0.587 0.424 None gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
N/S 15283 Ig-104 76 rs1326395034 0.39 -0.789 0.999 D 0.587 0.424 None gnomAD-4.0.0 6.20078E-06 None None None None N None 0 0 None 0 0 None 0 4.94234E-04 5.93645E-06 0 0
D/H 15466 Ig-106 76 rs758950651 0.6491 0.319 0.999 D 0.732 0.557 0.599286835281 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9E-06 0
D/Y 15466 Ig-106 76 None 0.5492 None 1.0 D 0.729 0.711 0.852740806646 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
D/H 15555 Ig-107 76 None 0.5763 None 1.0 D 0.675 0.556 0.578293158758 gnomAD-4.0.0 6.84902E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00176E-07 0 0
D/N 15555 Ig-107 76 rs754162662 0.1555 None 1.0 N 0.705 0.378 0.382925413656 gnomAD-4.0.0 6.84902E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00176E-07 0 0
N/K 15641 Ig-108 74 None 0.9961 None 1.0 N 0.713 0.462 0.225902525712 gnomAD-4.0.0 1.59452E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86362E-06 0 0
N/K 16039 Ig-109 72 None 0.9964 None 1.0 D 0.727 0.571 0.312306559268 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
N/D 17031 Ig-111 77 rs886044006 0.9377 None 0.999 D 0.638 0.685 0.380394304726 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
N/K 17031 Ig-111 77 None 0.9968 None 1.0 D 0.748 0.518 0.255777322467 gnomAD-4.0.0 6.8467E-07 None None None None I None 0 0 None 3.83289E-05 0 None 0 0 0 0 0
N/S 17031 Ig-111 77 rs749251609 0.7347 -1.002 0.999 D 0.597 0.588 0.253205268125 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.67E-05 0
N/S 17031 Ig-111 77 rs749251609 0.7347 -1.002 0.999 D 0.597 0.588 0.253205268125 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 17031 Ig-111 77 rs749251609 0.7347 -1.002 0.999 D 0.597 0.588 0.253205268125 gnomAD-4.0.0 3.8488E-06 None None None None I None 0 0 None 0 0 None 0 0 7.19059E-06 0 0
N/D 17748 Ig-113 72 rs1279556849 0.9822 -0.999 0.999 D 0.635 0.684 0.358948522604 gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
N/D 17748 Ig-113 72 rs1279556849 0.9822 -0.999 0.999 D 0.635 0.684 0.358948522604 gnomAD-4.0.0 1.59247E-06 None None None None I None 5.66572E-05 0 None 0 0 None 0 0 0 0 0
N/S 18049 Ig-114 82 rs562393563 0.734 -0.862 0.999 N 0.568 0.644 0.252681307341 gnomAD-2.1.1 1.22E-05 None None None None N None 0 0 None 0 5.59E-05 None 3.33E-05 None 0 9E-06 0
N/S 18049 Ig-114 82 rs562393563 0.734 -0.862 0.999 N 0.568 0.644 0.252681307341 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94553E-04 None 0 0 0 0 0
N/S 18049 Ig-114 82 rs562393563 0.734 -0.862 0.999 N 0.568 0.644 0.252681307341 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
N/S 18049 Ig-114 82 rs562393563 0.734 -0.862 0.999 N 0.568 0.644 0.252681307341 gnomAD-4.0.0 8.70897E-06 None None None None N None 0 0 None 0 2.23684E-05 None 0 0 8.50428E-06 3.31543E-05 0
N/S 18768 Ig-116 81 None 0.6243 None 0.999 N 0.581 0.622 0.289847578895 gnomAD-4.0.0 1.62068E-06 None None None None I None 0 0 None 0 0 None 0 0 2.91026E-06 0 0
N/T 19167 Ig-117 73 None 0.9067 None 0.999 D 0.705 0.728 0.425970041486 gnomAD-4.0.0 4.78077E-06 None None None None I None 0 0 None 0 0 None 0 0 8.58222E-06 0 0
N/K 19463 Ig-118 73 None 0.9993 None 1.0 D 0.745 0.519 0.176091768786 gnomAD-4.0.0 6.84286E-07 None None None None N None 0 0 None 0 2.52232E-05 None 0 0 0 0 0
N/S 19861 Ig-119 72 None 0.9313 None 0.999 N 0.558 0.619 0.292062946507 gnomAD-4.0.0 1.59214E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02572E-05
N/H 20155 Ig-120 76 rs1321298157 0.9473 None 1.0 D 0.753 0.719 0.389596023526 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.56E-05 0 0 0 None 0 0 0 0 0
N/H 20155 Ig-120 76 rs1321298157 0.9473 None 1.0 D 0.753 0.719 0.389596023526 gnomAD-4.0.0 6.5767E-06 None None None None I None 0 6.55738E-05 None 0 0 None 0 0 0 0 0
N/K 20155 Ig-120 76 None 0.9982 None 1.0 D 0.763 0.655 0.290222751274 gnomAD-4.0.0 3.18451E-06 None None None None I None 0 0 None 0 0 None 0 0 5.7202E-06 0 0
N/S 20155 Ig-120 76 rs369044697 0.4656 -0.82 0.999 N 0.603 0.633 None gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
N/S 20155 Ig-120 76 rs369044697 0.4656 -0.82 0.999 N 0.603 0.633 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 20155 Ig-120 76 rs369044697 0.4656 -0.82 0.999 N 0.603 0.633 None gnomAD-4.0.0 3.84575E-06 None None None None I None 0 0 None 0 0 None 0 0 4.78904E-06 0 2.84592E-05
N/I 20553 Ig-121 75 None 0.9832 None 1.0 D 0.731 0.728 0.660135772981 gnomAD-4.0.0 1.59256E-06 None None None None N None 0 0 None 4.77236E-05 0 None 0 0 0 0 0
N/K 20553 Ig-121 75 rs1009639599 0.9983 -0.136 1.0 D 0.745 0.622 0.252162846088 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
N/K 20553 Ig-121 75 rs1009639599 0.9983 -0.136 1.0 D 0.745 0.622 0.252162846088 gnomAD-4.0.0 6.8445E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99672E-07 0 0
N/K 21250 Ig-123 74 rs773738001 0.9969 -0.404 1.0 D 0.717 0.541 0.336155897331 gnomAD-2.1.1 8.11E-06 None None None None I None 0 0 None 0 1.13289E-04 None 0 None 0 0 0
N/K 21250 Ig-123 74 rs773738001 0.9969 -0.404 1.0 D 0.717 0.541 0.336155897331 gnomAD-4.0.0 3.19096E-06 None None None None I None 0 0 None 0 5.58534E-05 None 0 0 0 0 0
N/H 21543 Ig-124 75 rs745843637 0.9824 -0.982 1.0 D 0.739 0.7 0.352476196916 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
N/H 21543 Ig-124 75 rs745843637 0.9824 -0.982 1.0 D 0.739 0.7 0.352476196916 gnomAD-4.0.0 1.59374E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.0292E-05
N/K 21543 Ig-124 75 rs2048644499 0.999 None 1.0 D 0.727 0.569 0.223847106136 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
N/K 21543 Ig-124 75 rs2048644499 0.999 None 1.0 D 0.727 0.569 0.223847106136 gnomAD-4.0.0 6.57436E-06 None None None None N None 0 6.54879E-05 None 0 0 None 0 0 0 0 0
N/S 21940 Ig-125 75 rs762866554 0.9558 -0.253 0.999 N 0.605 0.547 0.289098819767 gnomAD-2.1.1 4.43E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.44E-06 0
N/S 21940 Ig-125 75 rs762866554 0.9558 -0.253 0.999 N 0.605 0.547 0.289098819767 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 21940 Ig-125 75 rs762866554 0.9558 -0.253 0.999 N 0.605 0.547 0.289098819767 gnomAD-4.0.0 1.73652E-05 None None None None N None 0 0 None 0 0 None 0 0 2.35237E-05 0 0
N/K 22338 Ig-126 74 rs761241302 0.9992 -0.196 1.0 D 0.729 0.543 0.203808441222 gnomAD-2.1.1 5.01E-05 None None None None I None 0 0 None 0 0 None 0 None 0 1.09783E-04 0
N/K 22338 Ig-126 74 rs761241302 0.9992 -0.196 1.0 D 0.729 0.543 0.203808441222 gnomAD-3.1.2 5.26E-05 None None None None I None 0 0 0 0 0 None 0 0 1.17696E-04 0 0
N/K 22338 Ig-126 74 rs761241302 0.9992 -0.196 1.0 D 0.729 0.543 0.203808441222 gnomAD-4.0.0 8.18319E-05 None None None None I None 0 0 None 0 0 None 0 0 1.10223E-04 0 3.20441E-05
N/D 22627 Ig-127 68 None 0.9835 None 0.999 D 0.62 0.653 0.329540904979 gnomAD-4.0.0 1.59202E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02608E-05
N/K 22627 Ig-127 68 rs561184293 0.999 -0.205 1.0 D 0.732 0.558 0.211220785272 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 0 None 9.8E-05 None 0 0 0
N/K 22627 Ig-127 68 rs561184293 0.999 -0.205 1.0 D 0.732 0.558 0.211220785272 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
N/K 22627 Ig-127 68 rs561184293 0.999 -0.205 1.0 D 0.732 0.558 0.211220785272 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 0 None None None 1E-03 None
N/K 22627 Ig-127 68 rs561184293 0.999 -0.205 1.0 D 0.732 0.558 0.211220785272 gnomAD-4.0.0 6.81767E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.20776E-04 0
N/S 23024 Ig-128 75 rs1205211838 0.6578 -0.926 0.999 N 0.572 0.632 0.303123707472 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.63E-05 None 0 None 0 0 0
N/S 23024 Ig-128 75 rs1205211838 0.6578 -0.926 0.999 N 0.572 0.632 0.303123707472 gnomAD-4.0.0 3.18511E-06 None None None None N None 0 0 None 0 2.78598E-05 None 0 0 2.85994E-06 0 0
N/H 23419 Ig-129 75 None 0.9583 None 1.0 D 0.749 0.675 0.348324211639 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
N/I 23419 Ig-129 75 None 0.9819 None 1.0 N 0.748 0.678 0.754833360098 gnomAD-4.0.0 1.59169E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85941E-06 0 0
N/K 23419 Ig-129 75 rs374496130 0.9979 None 1.0 N 0.715 0.51 0.212008924253 gnomAD-4.0.0 6.84284E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99575E-07 0 0
N/T 24106 Ig-131 78 rs1386956312 0.9529 -0.529 0.999 D 0.675 0.718 0.529011059296 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
N/T 24106 Ig-131 78 rs1386956312 0.9529 -0.529 0.999 D 0.675 0.718 0.529011059296 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/T 24106 Ig-131 78 rs1386956312 0.9529 -0.529 0.999 D 0.675 0.718 0.529011059296 gnomAD-4.0.0 2.56909E-06 None None None None N None 0 0 None 0 0 None 0 0 4.80132E-06 0 0
N/H 24503 Ig-132 73 rs770989516 0.9875 -1.188 1.0 D 0.75 0.714 0.359357374593 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
N/H 24503 Ig-132 73 rs770989516 0.9875 -1.188 1.0 D 0.75 0.714 0.359357374593 gnomAD-4.0.0 1.59234E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85982E-06 0 0
N/D 25188 Ig-134 78 None 0.9888 None 0.999 D 0.615 0.655 0.480198768302 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/K 25585 Ig-135 72 rs1171173179 0.9986 -0.035 1.0 D 0.722 0.633 0.266385636622 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14811E-04 0 None 0 0 None 0 None 0 0 0
N/K 25585 Ig-135 72 rs1171173179 0.9986 -0.035 1.0 D 0.722 0.633 0.266385636622 gnomAD-3.1.2 1.97E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
N/K 25585 Ig-135 72 rs1171173179 0.9986 -0.035 1.0 D 0.722 0.633 0.266385636622 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/D 25874 Ig-136 77 None 0.9599 None 0.999 D 0.639 0.68 0.368369118721 gnomAD-4.0.0 6.84341E-07 None None None None N None 0 0 None 0 2.52258E-05 None 0 0 0 0 0
N/H 25874 Ig-136 77 None 0.9222 None 1.0 D 0.745 0.734 0.418467456957 gnomAD-4.0.0 6.84341E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99611E-07 0 0
N/K 25874 Ig-136 77 rs766227814 0.9974 -0.556 1.0 D 0.737 0.516 0.318252033908 gnomAD-2.1.1 9.56E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.94502E-04 0
N/K 25874 Ig-136 77 rs766227814 0.9974 -0.556 1.0 D 0.737 0.516 0.318252033908 gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 0 None 0 0 7.35E-05 0 0
N/K 25874 Ig-136 77 rs766227814 0.9974 -0.556 1.0 D 0.737 0.516 0.318252033908 gnomAD-4.0.0 3.71907E-06 None None None None N None 0 0 None 0 0 None 0 0 5.08661E-06 0 0
N/S 25874 Ig-136 77 rs1706835764 0.3771 None 0.999 N 0.599 0.615 0.31411915649 gnomAD-4.0.0 1.59199E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85968E-06 0 0
N/I 26270 Ig-137 78 None 0.9928 None 1.0 D 0.725 0.693 0.808133268326 gnomAD-4.0.0 2.75281E-06 None None None None I None 0 0 None 0 0 None 0 0 3.60717E-06 0 0
N/S 26270 Ig-137 78 rs1239041708 0.7197 None 0.999 N 0.575 0.623 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.56E-05 0 0 0 None 0 0 0 0 0
N/S 26270 Ig-137 78 rs1239041708 0.7197 None 0.999 N 0.575 0.623 None gnomAD-4.0.0 1.246E-06 None None None None I None 0 1.71415E-05 None 0 0 None 0 0 8.49706E-07 0 0
N/T 26270 Ig-137 78 rs1239041708 0.93 None 0.999 D 0.721 0.718 0.503002171853 gnomAD-4.0.0 6.88203E-07 None None None None I None 0 0 None 0 0 None 0 0 9.01791E-07 0 0
N/K 26667 Ig-138 74 None 0.9986 None 1.0 D 0.741 0.617 0.319402600006 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31252E-06 0 0
N/D 26956 Ig-139 77 None 0.9579 None 0.996 D 0.532 0.569 0.311387274539 gnomAD-4.0.0 1.59154E-06 None None None None I None 0 0 None 0 0 None 1.88267E-05 0 0 0 0
N/S 27353 Ig-140 76 rs1704729039 0.636 None 0.999 N 0.547 0.604 0.316198179892 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/T 28434 Ig-143 77 rs758519100 0.9738 -0.477 0.999 D 0.683 0.696 0.518752145996 gnomAD-2.1.1 7.15E-06 None None None None I None 8.27E-05 0 None 0 0 None 0 None 0 0 0
N/T 28434 Ig-143 77 rs758519100 0.9738 -0.477 0.999 D 0.683 0.696 0.518752145996 gnomAD-3.1.2 1.97E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 0 0 0
N/T 28434 Ig-143 77 rs758519100 0.9738 -0.477 0.999 D 0.683 0.696 0.518752145996 gnomAD-4.0.0 5.0747E-06 None None None None I None 8.73515E-05 0 None 0 0 None 0 0 0 0 0
N/D 28829 Ig-144 75 rs371485481 0.9283 -0.962 0.996 N 0.522 0.588 None gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.66223E-04
N/D 28829 Ig-144 75 rs371485481 0.9283 -0.962 0.996 N 0.522 0.588 None gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 6.55E-05 0 0 0 None 0 0 0 0 0
N/D 28829 Ig-144 75 rs371485481 0.9283 -0.962 0.996 N 0.522 0.588 None gnomAD-4.0.0 2.47904E-06 None None None None I None 1.33494E-05 5.00167E-05 None 0 0 None 0 0 0 0 0
N/H 28829 Ig-144 75 None 0.9125 None 1.0 N 0.699 0.631 0.325263233342 gnomAD-4.0.0 2.05289E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69859E-06 0 0
N/D 29916 Ig-147 75 rs1308602245 0.9784 -1.62 0.999 D 0.595 0.664 0.379366414296 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
N/D 29916 Ig-147 75 rs1308602245 0.9784 -1.62 0.999 D 0.595 0.664 0.379366414296 gnomAD-4.0.0 6.84467E-07 None None None None N None 0 2.23644E-05 None 0 0 None 0 0 0 0 0
N/Y 29916 Ig-147 75 rs1308602245 0.987 -0.469 1.0 D 0.723 0.714 0.745525825506 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
N/Y 29916 Ig-147 75 rs1308602245 0.987 -0.469 1.0 D 0.723 0.714 0.745525825506 gnomAD-4.0.0 4.79127E-06 None None None None N None 0 0 None 0 0 None 0 0 6.29875E-06 0 0
N/H 30603 Ig-149 72 rs1698703188 0.9601 None 1.0 D 0.747 0.669 0.493226133426 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/H 30603 Ig-149 72 rs1698703188 0.9601 None 1.0 D 0.747 0.669 0.493226133426 gnomAD-4.0.0 2.56893E-06 None None None None I None 0 0 None 0 0 None 0 0 4.80381E-06 0 0
N/K 30603 Ig-149 72 rs1234224065 0.9968 -0.074 1.0 D 0.727 0.592 0.31291088546 gnomAD-2.1.1 4.04E-06 None None None None I None 0 2.91E-05 None 0 0 None 0 None 0 0 0
N/K 30603 Ig-149 72 rs1234224065 0.9968 -0.074 1.0 D 0.727 0.592 0.31291088546 gnomAD-4.0.0 3.19405E-06 None None None None I None 0 4.58232E-05 None 0 0 None 0 0 0 0 0
N/S 30603 Ig-149 72 rs794729533 0.7153 None 0.999 N 0.582 0.542 0.318540980066 gnomAD-4.0.0 4.11169E-06 None None None None I None 0 0 None 0 0 None 0 0 5.40513E-06 0 0
N/D 31292 Ig-151 75 rs767641332 0.9569 -0.495 0.999 N 0.606 0.555 None gnomAD-2.1.1 3.21E-05 None None None None I None 0 0 None 0 0 None 0 None 0 7.1E-05 0
N/D 31292 Ig-151 75 rs767641332 0.9569 -0.495 0.999 N 0.606 0.555 None gnomAD-4.0.0 1.16309E-05 None None None None I None 0 0 None 0 0 None 0 0 1.43908E-05 0 1.65634E-05
N/Y 31292 Ig-151 75 None 0.9797 None 1.0 D 0.66 0.705 0.722118035549 gnomAD-4.0.0 6.84172E-07 None None None None I None 2.98793E-05 0 None 0 0 None 0 0 0 0 0
N/K 31692 Ig-152 72 rs769796501 0.9995 -0.237 1.0 D 0.727 0.616 0.233785782151 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/K 31692 Ig-152 72 rs769796501 0.9995 -0.237 1.0 D 0.727 0.616 0.233785782151 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
N/K 31692 Ig-152 72 rs769796501 0.9995 -0.237 1.0 D 0.727 0.616 0.233785782151 gnomAD-4.0.0 2.47937E-06 None None None None I None 0 0 None 0 0 None 0 0 0 4.393E-05 0
N/T 31692 Ig-152 72 rs772560479 0.9814 -0.493 0.999 N 0.699 0.733 0.39724302092 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
N/Y 31692 Ig-152 72 None 0.9947 None 1.0 D 0.721 0.692 0.58411752329 gnomAD-4.0.0 1.59235E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86138E-06 0 0
N/K 32089 Ig-153 73 rs1695801999 0.9964 None 1.0 D 0.713 0.582 0.190952846119 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
N/K 32089 Ig-153 73 rs1695801999 0.9964 None 1.0 D 0.713 0.582 0.190952846119 gnomAD-4.0.0 6.57618E-06 None None None None N None 2.41453E-05 0 None 0 0 None 0 0 0 0 0
N/H 33177 Ig-156 77 None 0.971 None 1.0 D 0.735 0.691 0.370424759081 gnomAD-4.0.0 1.59132E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
N/S 33177 Ig-156 77 rs761530189 0.5487 -0.494 0.996 N 0.59 0.642 0.298745278005 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 9.94E-05 0 None 0 None 0 0 0
N/S 33177 Ig-156 77 rs761530189 0.5487 -0.494 0.996 N 0.59 0.642 0.298745278005 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
N/S 33177 Ig-156 77 rs761530189 0.5487 -0.494 0.996 N 0.59 0.642 0.298745278005 gnomAD-4.0.0 7.43634E-06 None None None None N None 0 0 None 3.37838E-05 0 None 0 0 9.32372E-06 0 0
N/H 33274 Ig-157 72 None 0.9728 None 1.0 N 0.772 0.686 0.326345978581 gnomAD-4.0.0 6.90743E-07 None None None None I None 0 0 None 0 0 None 0 0 9.06571E-07 0 0
N/T 33274 Ig-157 72 None 0.9365 None 1.0 N 0.737 0.681 0.448794319169 gnomAD-4.0.0 1.62711E-06 None None None None I None 0 0 None 0 2.79705E-05 None 0 0 0 0 0
N/Y 33274 Ig-157 72 None 0.9945 None 1.0 N 0.761 0.724 0.662192778189 gnomAD-4.0.0 1.38149E-06 None None None None I None 0 0 None 0 0 None 0 0 1.81314E-06 0 0
N/S 33574 Ig-158 79 rs1691356141 0.7925 None 0.879 D 0.525 0.624 0.357313475932 gnomAD-4.0.0 3.40251E-06 None None None None I None 0 0 None 0 2.80222E-05 None 0 0 0 1.61155E-05 0
N/S 34213 Ig-160 77 rs375332499 0.4399 -0.752 0.449 N 0.259 0.253 None gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
N/S 34213 Ig-160 77 rs375332499 0.4399 -0.752 0.449 N 0.259 0.253 None gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
N/S 34213 Ig-160 77 rs375332499 0.4399 -0.752 0.449 N 0.259 0.253 None gnomAD-4.0.0 3.0982E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69512E-06 1.09782E-05 3.20205E-05
N/D 34440 Ig-162 78 rs564640252 0.9911 -1.854 0.999 D 0.632 0.799 0.60849730516 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.06868E-04 0
N/D 34440 Ig-162 78 rs564640252 0.9911 -1.854 0.999 D 0.632 0.799 0.60849730516 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 0 None None None 1E-03 None
N/D 34440 Ig-162 78 rs564640252 0.9911 -1.854 0.999 D 0.632 0.799 0.60849730516 gnomAD-4.0.0 6.56435E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.07039E-04 0
N/T 34440 Ig-162 78 None 0.9777 None 0.999 D 0.717 0.884 0.723355570506 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/D 35363 Ig-165 78 None 0.3174 None 0.124 N 0.621 0.048 0.0884992946249 gnomAD-4.0.0 1.59091E-06 None None None None I None 0 2.28634E-05 None 0 0 None 0 0 0 0 0
G/R 35363 Ig-165 78 rs1575217507 0.3981 None 0.497 N 0.692 0.052 0.250579442822 gnomAD-3.1.2 1.31E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
G/R 35363 Ig-165 78 rs1575217507 0.3981 None 0.497 N 0.692 0.052 0.250579442822 gnomAD-4.0.0 1.31458E-05 None None None None I None 4.82835E-05 0 None 0 0 None 0 0 0 0 0
N/K 35496 Ig-166 77 None 0.9913 None 0.997 D 0.67 0.413 0.191931220699 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/S 35681 Ig-167 75 None 0.2554 None 0.999 N 0.579 0.264 0.195762928549 gnomAD-4.0.0 2.40064E-06 None None None None I None 1.26695E-04 0 None 0 0 None 0 0 0 0 0
N/T 35778 Ig-168 77 rs1304770151 0.9043 -0.802 0.999 N 0.689 0.698 0.36893422563 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.