Structural position:

  • Domain Type: Ig
  • Aligned Position: 164
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand G

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
G/R 87 Ig-1 82 rs756996890 0.8602 0.001 1.0 D 0.865 0.819 0.873851217738 gnomAD-2.1.1 7.95E-06 None None None -2.239(TCAP) N None 0 0 None 0 0 None 3.27E-05 None 0 8.79E-06 0
G/R 87 Ig-1 82 rs756996890 0.8602 0.001 1.0 D 0.865 0.819 0.873851217738 gnomAD-4.0.0 1.36819E-06 None None None -2.239(TCAP) N None 0 4.47187E-05 None 0 0 None 0 0 0 0 0
G/V 87 Ig-1 82 None 0.9411 None 1.0 D 0.837 0.831 0.931201369921 gnomAD-4.0.0 1.36819E-06 None None None -2.076(TCAP) N None 0 0 None 0 0 None 0 0 1.79869E-06 0 0
G/R 183 Ig-2 80 rs757439753 0.986 -0.383 1.0 D 0.864 0.728 0.895147227962 gnomAD-2.1.1 1.19E-05 None None None -2.419(TCAP) I None 0 0 None 0 0 None 9.8E-05 None 0 0 0
G/R 183 Ig-2 80 rs757439753 0.986 -0.383 1.0 D 0.864 0.728 0.895147227962 gnomAD-3.1.2 6.57E-06 None None None -2.419(TCAP) I None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
G/R 183 Ig-2 80 rs757439753 0.986 -0.383 1.0 D 0.864 0.728 0.895147227962 gnomAD-4.0.0 1.11522E-05 None None None -2.419(TCAP) I None 0 0 None 0 0 None 0 0 0 1.97628E-04 0
G/E 1163 Ig-4 82 rs765678606 0.9882 -1.262 1.0 D 0.832 0.744 None gnomAD-2.1.1 7.08E-06 None None None None I None 8.01E-05 0 None 0 0 None 0 None 0 0 0
G/E 1163 Ig-4 82 rs765678606 0.9882 -1.262 1.0 D 0.832 0.744 None gnomAD-3.1.2 3.29E-05 None None None None I None 1.20668E-04 0 0 0 0 None 0 0 0 0 0
G/E 1163 Ig-4 82 rs765678606 0.9882 -1.262 1.0 D 0.832 0.744 None gnomAD-4.0.0 3.28541E-05 None None None None I None 1.20668E-04 0 None 0 0 None 0 0 0 0 0
G/D 1637 Ig-7 82 None 0.9915 None 1.0 D 0.856 0.894 0.591791014774 gnomAD-4.0.0 1.36836E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.31976E-05 0
G/D 1919 Ig-9 79 None 0.9648 None 1.0 D 0.873 0.669 0.274366138417 gnomAD-4.0.0 6.36207E-06 None None None None I None 0 0 None 0 0 None 0 0 8.56976E-06 0 3.02151E-05
G/A 2158 Ig-10 81 None 0.9276 None 1.0 D 0.751 0.85 0.579040693538 gnomAD-4.0.0 1.32035E-05 None None None None N None 0 0 None 0 0 None 0 0 1.44375E-05 0 0
G/R 2158 Ig-10 81 None 0.9915 None 1.0 D 0.869 0.851 0.771111349424 gnomAD-4.0.0 1.59064E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
L/H 2434 Ig-13 79 rs774798625 0.2472 -1.079 0.999 N 0.783 0.499 0.843933267728 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
L/H 2434 Ig-13 79 rs774798625 0.2472 -1.079 0.999 N 0.783 0.499 0.843933267728 gnomAD-4.0.0 3.42042E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49653E-06 0 0
L/R 2434 Ig-13 79 rs774798625 0.2608 -0.349 0.984 N 0.739 0.506 None gnomAD-2.1.1 7.99E-06 None None None None N None 1.23062E-04 0 None 0 0 None 0 None 0 0 0
L/R 2434 Ig-13 79 rs774798625 0.2608 -0.349 0.984 N 0.739 0.506 None gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
L/R 2434 Ig-13 79 rs774798625 0.2608 -0.349 0.984 N 0.739 0.506 None gnomAD-4.0.0 4.33712E-06 None None None None N None 9.34405E-05 0 None 0 0 None 0 0 0 0 0
G/R 2520 Ig-14 76 None 0.9627 None 1.0 D 0.719 0.733 0.749366424934 gnomAD-4.0.0 1.36824E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79866E-06 0 0
G/V 2520 Ig-14 76 rs1173402678 0.9764 None 1.0 D 0.701 0.724 0.850167568098 gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 8.64553E-04 0 None 0 0 0 0 0
G/V 2520 Ig-14 76 rs1173402678 0.9764 None 1.0 D 0.701 0.724 0.850167568098 gnomAD-4.0.0 3.71777E-06 None None None None I None 0 0 None 1.68908E-04 0 None 0 0 8.47489E-07 0 0
G/R 2869 Ig-18 75 rs764173950 0.8744 -0.351 1.0 D 0.797 0.708 0.856686960939 gnomAD-2.1.1 2.48E-05 None None None None I None 0 5.65E-05 None 0 5.02E-05 None 0 None 0 3.1E-05 0
G/R 2869 Ig-18 75 rs764173950 0.8744 -0.351 1.0 D 0.797 0.708 0.856686960939 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/R 2869 Ig-18 75 rs764173950 0.8744 -0.351 1.0 D 0.797 0.708 0.856686960939 gnomAD-4.0.0 8.0546E-06 None None None None I None 0 3.33378E-05 None 0 2.22777E-05 None 0 0 7.62695E-06 1.09791E-05 0
G/V 2869 Ig-18 75 None 0.9442 None 1.0 D 0.773 0.735 0.919509768602 gnomAD-4.0.0 1.59046E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85644E-06 0 0
G/R 3223 Ig-22 77 None 0.9591 None 1.0 N 0.785 0.528 0.328222422547 gnomAD-4.0.0 6.84105E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15934E-05 0
G/D 3423 Ig-24 79 rs1000268203 0.8902 None 1.0 D 0.873 0.667 0.676505548274 gnomAD-4.0.0 1.5908E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85704E-06 0 0
G/S 3423 Ig-24 79 rs2088199501 0.4701 None 1.0 D 0.822 0.646 0.615566891949 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.06782E-04 0
G/S 3423 Ig-24 79 rs2088199501 0.4701 None 1.0 D 0.822 0.646 0.615566891949 gnomAD-4.0.0 6.57237E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.06782E-04 0
G/V 3423 Ig-24 79 None 0.9484 None 1.0 D 0.853 0.742 0.952184408665 gnomAD-4.0.0 1.5908E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
G/E 3546 Ig-25 82 None 0.9074 None None None None 0.574 None gnomAD-4.0.0 2.75712E-06 None None None None I None 0 0 None 0 0 None 0 0 3.6214E-06 0 0
G/E 3739 Ig-26 80 rs371678138 0.4004 -1.759 None None None 0.288 None gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
G/E 3739 Ig-26 80 rs371678138 0.4004 -1.759 None None None 0.288 None gnomAD-4.0.0 4.10651E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39839E-06 0 0
G/R 3739 Ig-26 80 None 0.338 None None None None 0.312 None gnomAD-4.0.0 6.84404E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99726E-07 0 0
G/R 3899 Ig-27 80 None 0.5015 None 1.0 D 0.872 0.63 None gnomAD-4.0.0 1.59119E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85806E-06 0 0
G/D 4018 Ig-28 81 None 0.8839 None 1.0 D 0.859 0.593 0.168933306366 gnomAD-4.0.0 2.73761E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79886E-06 2.31868E-05 0
G/S 4018 Ig-28 81 rs759214389 0.5821 -0.608 1.0 D 0.804 0.604 0.126345400529 gnomAD-2.1.1 1.21E-05 None None None None I None 0 8.7E-05 None 0 0 None 0 None 0 0 0
G/S 4018 Ig-28 81 rs759214389 0.5821 -0.608 1.0 D 0.804 0.604 0.126345400529 gnomAD-4.0.0 4.77748E-06 None None None None I None 0 6.85965E-05 None 0 0 None 0 0 0 0 0
G/R 4684 Ig-29 79 rs377579941 0.3645 -0.339 0.856 D 0.589 0.625 None gnomAD-2.1.1 5.69E-05 None None None None I None 3.85538E-04 0 None 0 1.17661E-04 None 0 None 0 0 1.93798E-04
G/R 4684 Ig-29 79 rs377579941 0.3645 -0.339 0.856 D 0.589 0.625 None gnomAD-3.1.2 9.2E-05 None None None None I None 3.13813E-04 0 0 0 0 None 0 0 1.47E-05 0 0
G/R 4684 Ig-29 79 rs377579941 0.3645 -0.339 0.856 D 0.589 0.625 None gnomAD-4.0.0 2.4437E-05 None None None None I None 3.06646E-04 0 None 0 0 None 0 0 1.14801E-05 1.3875E-05 1.72016E-05
G/D 4779 Ig-30 80 None 0.9018 None 1.0 D 0.835 0.771 0.551593237191 gnomAD-4.0.0 1.59144E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02425E-05
G/V 4874 Ig-31 80 None 0.949 None 1.0 D 0.833 0.786 0.930366645497 gnomAD-4.0.0 6.84249E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99468E-07 0 0
G/A 4967 Ig-32 80 None 0.4323 None 1.0 D 0.744 0.713 0.576708290288 gnomAD-4.0.0 1.62461E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.08356E-05
G/R 4967 Ig-32 80 rs267599070 0.7433 0.107 1.0 D 0.847 0.738 0.870683688638 gnomAD-2.1.1 4.21E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.17E-06 0
G/R 4967 Ig-32 80 rs267599070 0.7433 0.107 1.0 D 0.847 0.738 0.870683688638 gnomAD-4.0.0 3.24923E-06 None None None None I None 0 0 None 0 0 None 0 0 5.79811E-06 0 0
G/C 5061 Ig-33 81 rs1441268700 0.8206 None 1.0 D 0.812 0.785 0.852862438607 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/C 5061 Ig-33 81 rs1441268700 0.8206 None 1.0 D 0.812 0.785 0.852862438607 gnomAD-4.0.0 1.85989E-06 None None None None I None 0 0 None 0 0 None 0 0 2.54409E-06 0 0
G/S 5061 Ig-33 81 rs1441268700 0.428 -0.349 1.0 D 0.809 0.713 0.448891444097 gnomAD-2.1.1 6.37E-05 None None None None I None 1.14732E-04 0 None 0 0 None 0 None 0 6.48E-05 0
G/S 5061 Ig-33 81 rs1441268700 0.428 -0.349 1.0 D 0.809 0.713 0.448891444097 gnomAD-3.1.2 3.29E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 2.94E-05 0 0
G/S 5061 Ig-33 81 rs1441268700 0.428 -0.349 1.0 D 0.809 0.713 0.448891444097 gnomAD-4.0.0 8.6795E-06 None None None None I None 4.00513E-05 1.66733E-05 None 0 0 None 0 0 7.63227E-06 0 1.60159E-05
G/R 5154 Ig-34 80 None 0.9709 None 1.0 D 0.857 0.796 0.895805305044 gnomAD-4.0.0 6.87922E-07 None None None None I None 0 0 None 0 0 None 0 0 9.03556E-07 0 0
G/S 5154 Ig-34 80 rs772907723 0.7224 -0.459 1.0 D 0.793 0.732 0.627131723059 gnomAD-2.1.1 8.14E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.79E-05 0
G/S 5154 Ig-34 80 rs772907723 0.7224 -0.459 1.0 D 0.793 0.732 0.627131723059 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/S 5154 Ig-34 80 rs772907723 0.7224 -0.459 1.0 D 0.793 0.732 0.627131723059 gnomAD-4.0.0 1.30766E-05 None None None None I None 0 0 None 0 0 None 0 0 1.44711E-05 0 6.43708E-05
G/V 5154 Ig-34 80 None 0.9795 None 1.0 D 0.821 0.815 0.956621325844 gnomAD-4.0.0 1.61089E-06 None None None None I None 0 0 None 0 0 None 0 0 2.89973E-06 0 0
G/E 5247 Ig-35 80 rs767464148 0.9679 -0.876 1.0 D 0.843 0.747 0.856520570022 gnomAD-4.0.0 1.11584E-05 None None None None N None 0 0 None 0 1.94272E-04 None 0 0 0 0 0
G/D 5340 Ig-36 80 rs2080874147 0.8814 None 1.0 D 0.856 0.681 0.663816143375 gnomAD-4.0.0 2.74285E-06 None None None None N None 0 0 None 0 0 None 0 0 3.60455E-06 0 0
G/S 5340 Ig-36 80 rs759610759 0.626 -0.003 1.0 D 0.811 0.576 0.57433219186 gnomAD-2.1.1 4.07E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
G/S 5340 Ig-36 80 rs759610759 0.626 -0.003 1.0 D 0.811 0.576 0.57433219186 gnomAD-4.0.0 1.37117E-06 None None None None N None 2.99312E-05 0 None 0 0 None 0 0 9.01042E-07 0 0
G/R 5529 Ig-38 80 None 0.7845 None 1.0 D 0.851 0.511 0.695056991498 gnomAD-4.0.0 1.59423E-06 None None None None I None 0 0 None 0 0 None 0 2.41896E-04 0 0 0
G/D 5623 Ig-39 81 None 0.7813 None 1.0 D 0.859 0.554 0.610312411291 gnomAD-4.0.0 6.84853E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00203E-07 0 0
G/V 5623 Ig-39 81 rs768364912 0.9025 0.066 1.0 D 0.839 0.619 0.812223674915 gnomAD-2.1.1 2.02E-05 None None None None I None 0 0 None 0 1.67056E-04 None 0 None 0 8.93E-06 1.66778E-04
G/V 5623 Ig-39 81 rs768364912 0.9025 0.066 1.0 D 0.839 0.619 0.812223674915 gnomAD-4.0.0 5.47882E-06 None None None None I None 0 0 None 0 7.56125E-05 None 0 0 3.60081E-06 0 1.65837E-05
G/A 5716 Ig-40 80 None 0.7621 None 1.0 D 0.74 0.686 0.605229780939 gnomAD-4.0.0 6.84536E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65733E-05
G/D 5716 Ig-40 80 rs952474808 0.908 None 1.0 D 0.846 0.68 0.664105290246 gnomAD-4.0.0 6.16082E-06 None None None None I None 0 0 None 0 0 None 0 0 7.19923E-06 0 1.65733E-05
G/E 5809 Ig-41 80 rs765643296 0.9665 None 1.0 D 0.827 0.808 0.704587578234 gnomAD-4.0.0 1.36843E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.15939E-05 1.65656E-05
G/E 5902 Ig-42 80 rs1346456739 0.9545 -0.653 1.0 D 0.767 0.767 0.750126765191 gnomAD-2.1.1 4.04E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
G/E 5902 Ig-42 80 rs1346456739 0.9545 -0.653 1.0 D 0.767 0.767 0.750126765191 gnomAD-4.0.0 1.30212E-05 None None None None I None 0 2.23964E-05 None 0 0 None 0 0 1.62131E-05 0 0
G/R 5902 Ig-42 80 rs770836683 0.9635 -0.157 0.953 D 0.569 0.668 0.814358034838 gnomAD-2.1.1 4.04E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
G/R 5902 Ig-42 80 rs770836683 0.9635 -0.157 0.953 D 0.569 0.668 0.814358034838 gnomAD-4.0.0 1.59727E-06 None None None None I None 0 2.2899E-05 None 0 0 None 0 0 0 0 0
G/V 5902 Ig-42 80 rs1346456739 0.9677 None 1.0 D 0.756 0.801 0.918624825834 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/V 5902 Ig-42 80 rs1346456739 0.9677 None 1.0 D 0.756 0.801 0.918624825834 gnomAD-4.0.0 6.57834E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47063E-05 0 0
G/R 5998 Ig-43 80 rs757934638 0.9696 -0.236 1.0 D 0.877 0.627 0.873637900166 gnomAD-2.1.1 4.02E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
G/R 5998 Ig-43 80 rs757934638 0.9696 -0.236 1.0 D 0.877 0.627 0.873637900166 gnomAD-4.0.0 1.36888E-06 None None None None I None 0 0 None 0 0 None 0 0 8.99755E-07 0 1.65733E-05
G/S 6091 Ig-44 80 rs890606784 0.7302 None 1.0 D 0.801 0.747 0.574298552393 gnomAD-2.1.1 4.04E-06 None None None None I None 6.47E-05 0 None 0 0 None 0 None 0 0 0
G/S 6091 Ig-44 80 rs890606784 0.7302 None 1.0 D 0.801 0.747 0.574298552393 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/S 6091 Ig-44 80 rs890606784 0.7302 None 1.0 D 0.801 0.747 0.574298552393 gnomAD-4.0.0 2.56446E-06 None None None None I None 3.38467E-05 0 None 0 0 None 0 0 0 0 0
G/S 6185 Ig-45 81 rs1460731482 0.4216 -0.345 1.0 D 0.808 0.543 0.582074046126 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/S 6185 Ig-45 81 rs1460731482 0.4216 -0.345 1.0 D 0.808 0.543 0.582074046126 gnomAD-4.0.0 3.18279E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85865E-06 1.43283E-05 0
G/S 6278 Ig-46 80 rs397517488 0.452 -0.083 1.0 D 0.786 0.651 0.511105228888 gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 1.53846E-04 None 0 None 0 7.86E-06 1.41243E-04
G/S 6278 Ig-46 80 rs397517488 0.452 -0.083 1.0 D 0.786 0.651 0.511105228888 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/S 6278 Ig-46 80 rs397517488 0.452 -0.083 1.0 D 0.786 0.651 0.511105228888 gnomAD-4.0.0 1.61299E-05 None None None None I None 2.67201E-05 0 None 0 1.56138E-04 None 0 1.64799E-04 1.1031E-05 1.09946E-05 3.20708E-05
G/E 6464 Ig-48 80 None 0.9608 None 0.998 D 0.767 0.741 0.632648996995 gnomAD-4.0.0 1.59491E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86494E-06 0 0
G/R 6464 Ig-48 80 rs755082868 0.9441 None 1.0 D 0.763 0.691 0.621853638575 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.56E-05 0 0 0 None 0 0 0 0 0
G/R 6464 Ig-48 80 rs755082868 0.9441 None 1.0 D 0.763 0.691 0.621853638575 gnomAD-4.0.0 6.57505E-06 None None None None I None 0 6.5591E-05 None 0 0 None 0 0 0 0 0
G/A 6653 Ig-50 80 rs1446415238 0.672 -0.291 1.0 D 0.616 0.65 0.516326692288 gnomAD-2.1.1 8.44E-06 None None None None I None 0 0 None 0 0 None 7.24E-05 None 0 0 0
G/A 6653 Ig-50 80 rs1446415238 0.672 -0.291 1.0 D 0.616 0.65 0.516326692288 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
G/A 6653 Ig-50 80 rs1446415238 0.672 -0.291 1.0 D 0.616 0.65 0.516326692288 gnomAD-4.0.0 6.26272E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.13729E-04 0
G/D 6653 Ig-50 80 rs1446415238 0.8668 None 0.975 D 0.547 0.621 0.55025283692 gnomAD-4.0.0 1.38437E-06 None None None None I None 0 0 None 0 5.0615E-05 None 0 0 0 0 0
G/R 6653 Ig-50 80 None 0.9246 None 1.0 D 0.803 0.705 0.850381006097 gnomAD-4.0.0 1.63463E-06 None None None None I None 0 0 None 0 0 None 0 0 2.92535E-06 0 0
G/R 6840 Ig-52 80 None 0.9705 None 1.0 D 0.855 0.684 0.913998194909 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/V 6840 Ig-52 80 rs1413034567 0.9716 None 1.0 D 0.823 0.668 0.968543987747 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/V 6840 Ig-52 80 rs1413034567 0.9716 None 1.0 D 0.823 0.668 0.968543987747 gnomAD-4.0.0 6.57462E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47076E-05 0 0
G/R 6934 Ig-53 81 rs2079167703 0.8694 None 1.0 D 0.881 0.686 0.875557798454 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/R 6934 Ig-53 81 rs2079167703 0.8694 None 1.0 D 0.881 0.686 0.875557798454 gnomAD-4.0.0 5.20927E-06 None None None None I None 1.69635E-05 0 None 0 0 None 0 0 7.30048E-06 0 0
G/E 7027 Ig-54 80 rs2078958911 0.957 None 1.0 D 0.826 0.652 0.775756185 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/E 7027 Ig-54 80 rs2078958911 0.957 None 1.0 D 0.826 0.652 0.775756185 gnomAD-4.0.0 5.12718E-06 None None None None I None 0 0 None 0 0 None 0 0 9.57689E-06 0 0
G/R 7027 Ig-54 80 rs1237624593 0.9625 -0.124 1.0 D 0.851 0.662 0.850944246378 gnomAD-2.1.1 3.19E-05 None None None None I None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
G/R 7027 Ig-54 80 rs1237624593 0.9625 -0.124 1.0 D 0.851 0.662 0.850944246378 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/R 7027 Ig-54 80 rs1237624593 0.9625 -0.124 1.0 D 0.851 0.662 0.850944246378 gnomAD-4.0.0 6.5716E-06 None None None None I None 2.41243E-05 0 None 0 0 None 0 0 0 0 0
G/R 7123 Ig-55 80 rs377229283 0.9125 -0.031 1.0 D 0.783 0.592 0.86228062617 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
G/R 7123 Ig-55 80 rs377229283 0.9125 -0.031 1.0 D 0.783 0.592 0.86228062617 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/R 7123 Ig-55 80 rs377229283 0.9125 -0.031 1.0 D 0.783 0.592 0.86228062617 gnomAD-4.0.0 1.11596E-05 None None None None I None 0 0 None 0 0 None 0 0 1.18716E-05 0 6.40738E-05
G/D 7216 Ig-56 80 rs766206440 0.7734 -0.554 1.0 D 0.841 0.622 0.601523639021 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
G/D 7216 Ig-56 80 rs766206440 0.7734 -0.554 1.0 D 0.841 0.622 0.601523639021 gnomAD-4.0.0 1.5931E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02847E-05
G/S 7216 Ig-56 80 None 0.3807 None 1.0 D 0.79 0.638 0.545611132464 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/E 7498 Ig-59 80 None 0.9601 None 1.0 D 0.83 0.604 0.879581146893 gnomAD-4.0.0 1.60706E-06 None None None None I None 0 0 None 0 2.77654E-05 None 0 0 0 0 0
G/D 7594 Ig-60 80 None 0.9493 None 1.0 D 0.845 0.546 0.604580495079 gnomAD-4.0.0 1.59456E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43852E-05 0
G/V 7594 Ig-60 80 None 0.9757 None 1.0 D 0.833 0.585 0.926821394966 gnomAD-4.0.0 1.59456E-06 None None None None I None 0 0 None 0 2.77346E-05 None 0 0 0 0 0
G/D 7688 Ig-61 81 None 0.9196 None 1.0 D 0.863 0.549 0.610541524961 gnomAD-4.0.0 1.62351E-06 None None None None I None 0 0 None 0 0 None 0 0 2.94227E-06 0 0
G/E 7781 Ig-62 80 rs868631561 0.9925 None 0.885 D 0.513 0.766 0.739693031037 gnomAD-4.0.0 6.00161E-06 None None None None I None 0 0 None 0 0 None 0 0 0 3.03767E-04 0
G/E 7875 Ig-63 81 None 0.9482 None 1.0 D 0.791 0.721 0.747641037427 gnomAD-4.0.0 1.59444E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86408E-06 0 0
G/V 7968 Ig-64 80 None 0.9676 None 1.0 D 0.807 0.618 0.911182896716 gnomAD-4.0.0 1.37035E-06 None None None None N None 5.98086E-05 0 None 0 0 None 0 0 0 0 0
G/D 8064 Ig-65 80 None 0.8228 None 0.45 D 0.545 0.695 0.444404870569 gnomAD-4.0.0 1.59145E-06 None None None None I None 0 0 None 0 2.77285E-05 None 0 0 0 0 0
G/S 8157 Ig-66 80 rs753025964 0.5104 -0.455 1.0 D 0.789 0.627 0.546562531242 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
G/S 8157 Ig-66 80 rs753025964 0.5104 -0.455 1.0 D 0.789 0.627 0.546562531242 gnomAD-4.0.0 1.64213E-05 None None None None I None 0 0 None 0 0 None 0 0 2.15877E-05 0 0
G/V 8157 Ig-66 80 None 0.9122 None 1.0 D 0.819 0.691 0.933750783859 gnomAD-4.0.0 1.59131E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85842E-06 0 0
G/A 8250 Ig-67 80 rs1311136102 0.7419 -0.155 1.0 D 0.739 0.575 0.59904029974 gnomAD-2.1.1 7.15E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.57E-05 0
G/A 8250 Ig-67 80 rs1311136102 0.7419 -0.155 1.0 D 0.739 0.575 0.59904029974 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/A 8250 Ig-67 80 rs1311136102 0.7419 -0.155 1.0 D 0.739 0.575 0.59904029974 gnomAD-4.0.0 3.84371E-06 None None None None I None 0 0 None 0 0 None 0 0 7.18006E-06 0 0
G/A 8343 Ig-68 80 rs1288642142 0.7955 -0.155 1.0 D 0.739 0.61 0.63749958327 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 4.65E-05 0 0
G/A 8343 Ig-68 80 rs1288642142 0.7955 -0.155 1.0 D 0.739 0.61 0.63749958327 gnomAD-4.0.0 1.59204E-06 None None None None I None 0 0 None 0 0 None 1.88246E-05 0 0 0 0
G/R 8439 Ig-69 80 rs1177073291 0.9719 None 1.0 N 0.857 0.635 0.689113965555 gnomAD-4.0.0 6.84901E-07 None None None None I None 2.99347E-05 0 None 0 0 None 0 0 0 0 0
G/R 8535 Ig-70 80 None 0.897 None 1.0 D 0.853 0.782 0.697169835009 gnomAD-4.0.0 1.59257E-06 None None None None I None 0 0 None 0 2.77393E-05 None 0 0 0 0 0
G/S 8629 Ig-71 81 rs2077356013 0.6248 None 1.0 D 0.803 0.813 0.555237559564 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
G/S 8629 Ig-71 81 rs2077356013 0.6248 None 1.0 D 0.803 0.813 0.555237559564 gnomAD-4.0.0 6.57479E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.07211E-04 0
G/V 8629 Ig-71 81 None 0.9566 None 1.0 D 0.837 0.828 0.942225882153 gnomAD-4.0.0 1.59355E-06 None None None None I None 0 0 None 0 2.77393E-05 None 0 0 0 0 0
G/R 8722 Ig-72 80 None 0.9436 None 1.0 D 0.855 0.689 0.749798479323 gnomAD-4.0.0 1.59352E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02737E-05
G/R 9005 Ig-75 80 rs939492024 0.9068 None 1.0 D 0.855 0.759 0.85784730175 gnomAD-4.0.0 1.36852E-06 None None None None I None 0 0 None 0 0 None 0 1.73491E-04 0 0 1.65678E-05
G/A 9098 Ig-76 80 None 0.6451 None 1.0 D 0.739 0.765 0.553996833274 gnomAD-4.0.0 6.8425E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99523E-07 0 0
G/S 9098 Ig-76 80 rs772115815 0.4724 -0.365 1.0 D 0.79 0.82 0.585504228005 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 1.11284E-04 None 3.27E-05 None 0 0 0
G/S 9098 Ig-76 80 rs772115815 0.4724 -0.365 1.0 D 0.79 0.82 0.585504228005 gnomAD-4.0.0 3.18288E-06 None None None None I None 0 0 None 0 2.77316E-05 None 0 0 0 1.43287E-05 0
G/V 9098 Ig-76 80 None 0.9298 None 1.0 D 0.82 0.753 0.936918052032 gnomAD-4.0.0 6.8425E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65656E-05
G/R 9191 Ig-77 80 rs141502557 0.8465 0.044 1.0 D 0.871 0.744 0.608446283964 gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
G/R 9191 Ig-77 80 rs141502557 0.8465 0.044 1.0 D 0.871 0.744 0.608446283964 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 1.92753E-04 None 0 0 0 0 0
G/R 9191 Ig-77 80 rs141502557 0.8465 0.044 1.0 D 0.871 0.744 0.608446283964 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 1E-03 0 None None None 0 None
G/R 9191 Ig-77 80 rs141502557 0.8465 0.044 1.0 D 0.871 0.744 0.608446283964 gnomAD-4.0.0 1.8591E-06 None None None None I None 1.33316E-05 0 None 0 2.22856E-05 None 0 0 8.47643E-07 0 0
G/E 9284 Ig-78 80 rs770920718 0.9787 -0.903 1.0 D 0.844 0.76 0.717566290573 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.98E-06 0
G/E 9284 Ig-78 80 rs770920718 0.9787 -0.903 1.0 D 0.844 0.76 0.717566290573 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07469E-04 0
G/R 9284 Ig-78 80 rs2076727185 0.9682 None 1.0 D 0.873 0.779 0.835362870993 gnomAD-3.1.2 6.57E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
G/R 9284 Ig-78 80 rs2076727185 0.9682 None 1.0 D 0.873 0.779 0.835362870993 gnomAD-4.0.0 2.02986E-06 None None None None I None 0 6.15385E-05 None 0 0 None 0 0 1.20491E-06 0 0
G/V 9284 Ig-78 80 rs770920718 0.9863 -0.177 1.0 D 0.842 0.734 None gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.98E-06 0
G/V 9284 Ig-78 80 rs770920718 0.9863 -0.177 1.0 D 0.842 0.734 None gnomAD-4.0.0 4.81369E-06 None None None None I None 0 0 None 0 0 None 0 0 8.66126E-06 0 0
G/R 9380 Ig-79 80 rs370785476 0.9367 -0.243 1.0 None 0.855 0.639 None gnomAD-2.1.1 1.08E-05 None None None None I None 1.24069E-04 0 None 0 0 None 0 None 0 0 0
G/R 9380 Ig-79 80 rs370785476 0.9367 -0.243 1.0 None 0.855 0.639 None gnomAD-3.1.2 3.29E-05 None None None None I None 1.20715E-04 0 0 0 0 None 0 0 0 0 0
G/R 9380 Ig-79 80 rs370785476 0.9367 -0.243 1.0 None 0.855 0.639 None gnomAD-4.0.0 6.09E-06 None None None None I None 1.04884E-04 0 None 0 0 None 0 0 0 0 0
G/V 9476 Ig-80 80 None 0.9483 None 1.0 None 0.827 0.599 0.951045865265 gnomAD-4.0.0 1.59372E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85922E-06 0 0
G/R 9669 Ig-82 80 None 0.9769 None 1.0 None 0.859 0.806 0.874896931464 gnomAD-4.0.0 5.47421E-06 None None None None I None 0 0 None 0 0 None 0 0 7.19625E-06 0 0
G/A 9778 Ig-83 81 rs775854531 0.8958 -0.346 1.0 None 0.735 0.699 0.470237251169 gnomAD-2.1.1 2.81E-05 None None None None I None 0 2.02852E-04 None 0 0 None 0 None 0 0 0
G/A 9778 Ig-83 81 rs775854531 0.8958 -0.346 1.0 None 0.735 0.699 0.470237251169 gnomAD-4.0.0 4.78931E-06 None None None None I None 0 1.56523E-04 None 0 0 None 0 0 0 0 0
G/D 9778 Ig-83 81 rs775854531 0.9499 -0.976 1.0 None 0.854 0.667 0.510700632011 gnomAD-2.1.1 1.2E-05 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 1.77E-05 0
G/D 9778 Ig-83 81 rs775854531 0.9499 -0.976 1.0 None 0.854 0.667 0.510700632011 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/D 9778 Ig-83 81 rs775854531 0.9499 -0.976 1.0 None 0.854 0.667 0.510700632011 gnomAD-4.0.0 2.045E-05 None None None None I None 0 0 None 0 0 None 0 0 2.37325E-05 1.09798E-05 6.4041E-05
G/S 9778 Ig-83 81 rs1181765627 0.8046 -0.611 1.0 None 0.798 0.68 0.441949972293 gnomAD-2.1.1 4.01E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.86E-06 0
G/S 9778 Ig-83 81 rs1181765627 0.8046 -0.611 1.0 None 0.798 0.68 0.441949972293 gnomAD-4.0.0 6.84173E-06 None None None None I None 0 0 None 0 0 None 0 0 8.09489E-06 0 1.6564E-05
G/R 10157 Ig-86 80 None 0.9738 None 1.0 None 0.919 0.474 0.402614778071 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
K/E 13765 Ig-87 82 rs1376605407 0.8658 0.025 0.996 N 0.519 0.432 0.435152311215 gnomAD-2.1.1 4.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.95E-06 0
K/E 13765 Ig-87 82 rs1376605407 0.8658 0.025 0.996 N 0.519 0.432 0.435152311215 gnomAD-4.0.0 2.05607E-05 None None None None I None 0 0 None 0 0 None 0 0 2.70149E-05 0 0
N/K 13859 Ig-88 80 None 0.4985 None 0.818 N 0.205 0.134 0.0401082797425 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Y/C 13954 Ig-89 79 None 0.6539 None 0.004 D 0.409 0.311 0.37568098594 gnomAD-4.0.0 3.21484E-06 None None None None N None 0 0 None 0 0 None 0 0 5.76671E-06 0 0
Y/H 13954 Ig-89 79 None 0.7216 None 0.924 D 0.465 0.286 0.39724302092 gnomAD-4.0.0 2.74832E-06 None None None None N None 0 0 None 0 0 None 0 3.47464E-04 1.80369E-06 0 0
T/P 14043 Ig-90 79 None 0.983 None 0.999 N 0.863 0.475 0.371903410333 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
S/C 14397 Ig-94 79 rs1297192310 0.3013 -0.293 0.012 N 0.422 0.149 0.154104182512 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
S/Y 14397 Ig-94 79 rs1297192310 0.7323 -0.291 0.989 D 0.809 0.398 0.255270683199 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
S/Y 14397 Ig-94 79 rs1297192310 0.7323 -0.291 0.989 D 0.809 0.398 0.255270683199 gnomAD-4.0.0 1.59301E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43517E-05 0
S/Y 14753 Ig-98 79 None 0.6112 None 0.895 D 0.797 0.362 0.397540356873 gnomAD-4.0.0 1.5927E-06 None None None None N None 0 0 None 0 0 None 0 0 2.861E-06 0 0
T/I 14842 Ig-99 78 rs370782364 0.5134 0.247 0.992 D 0.589 0.454 None gnomAD-2.1.1 1.45E-05 None None None None N None 1.26167E-04 0 None 0 0 None 0 None 0 7.89E-06 0
T/I 14842 Ig-99 78 rs370782364 0.5134 0.247 0.992 D 0.589 0.454 None gnomAD-4.0.0 4.81056E-06 None None None None N None 1.21389E-04 0 None 0 2.54466E-05 None 0 0 1.80375E-06 0 0
T/S 14842 Ig-99 78 rs763625555 0.2553 -1.422 0.998 N 0.485 0.242 0.115124310173 gnomAD-2.1.1 3.27E-05 None None None None N None 0 0 None 0 0 None 2.67594E-04 None 0 0 0
T/S 14842 Ig-99 78 rs763625555 0.2553 -1.422 0.998 N 0.485 0.242 0.115124310173 gnomAD-4.0.0 2.0879E-05 None None None None N None 0 0 None 0 0 None 0 0 0 1.73984E-04 3.04841E-05
T/A 14931 Ig-100 79 rs779264506 0.271 -1.128 0.981 N 0.521 0.31 None gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.67E-05 0
T/A 14931 Ig-100 79 rs779264506 0.271 -1.128 0.981 N 0.521 0.31 None gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.89E-05 0 0
T/A 14931 Ig-100 79 rs779264506 0.271 -1.128 0.981 N 0.521 0.31 None gnomAD-4.0.0 1.61247E-05 None None None None N None 0 0 None 0 0 None 0 0 2.20524E-05 0 0
T/I 14931 Ig-100 79 rs1292868903 0.7436 None 0.999 N 0.764 0.396 0.244539031024 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/I 14931 Ig-100 79 rs1292868903 0.7436 None 0.999 N 0.764 0.396 0.244539031024 gnomAD-4.0.0 1.86053E-06 None None None None N None 0 0 None 0 0 None 0 0 2.54448E-06 0 0
T/N 14931 Ig-100 79 rs1292868903 0.5342 None 0.999 N 0.654 0.326 0.236890367714 gnomAD-4.0.0 1.36943E-06 None None None None N None 0 0 None 0 5.04872E-05 None 0 0 0 0 0
T/S 14931 Ig-100 79 None 0.335 None 0.905 N 0.323 0.185 0.110078149338 gnomAD-4.0.0 2.73886E-06 None None None None N None 0 0 None 0 0 None 0 0 3.60008E-06 0 0
T/N 15020 Ig-101 79 rs755201448 0.634 -0.559 0.961 D 0.662 0.368 0.256793551483 gnomAD-2.1.1 5.25E-05 None None None None N None 6.48E-05 0 None 0 0 None 3.93005E-04 None 0 0 0
T/N 15020 Ig-101 79 rs755201448 0.634 -0.559 0.961 D 0.662 0.368 0.256793551483 gnomAD-3.1.2 2.63E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 6.21633E-04 0
T/N 15020 Ig-101 79 rs755201448 0.634 -0.559 0.961 D 0.662 0.368 0.256793551483 gnomAD-4.0.0 2.54344E-05 None None None None N None 1.33676E-05 0 None 0 0 None 0 0 0 4.06665E-04 4.81139E-05
S/F 15469 Ig-106 79 rs376373678 0.9484 -0.745 0.999 D 0.748 0.624 None gnomAD-2.1.1 1.63E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.71E-05 1.67842E-04
S/F 15469 Ig-106 79 rs376373678 0.9484 -0.745 0.999 D 0.748 0.624 None gnomAD-3.1.2 2.64E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 4.42E-05 0 0
S/F 15469 Ig-106 79 rs376373678 0.9484 -0.745 0.999 D 0.748 0.624 None gnomAD-4.0.0 3.78731E-05 None None None None N None 1.33897E-05 0 None 0 0 None 0 0 4.58202E-05 0 9.62835E-05
G/S 16338 Ig-110 77 rs752053096 0.9447 None 1.0 D 0.833 0.686 0.576277098964 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/S 16338 Ig-110 77 rs752053096 0.9447 None 1.0 D 0.833 0.686 0.576277098964 gnomAD-4.0.0 6.58467E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47223E-05 0 0
G/S 17034 Ig-111 80 rs886042475 0.3052 -0.535 1.0 D 0.753 0.735 0.578877614382 gnomAD-2.1.1 2.01E-05 None None None None I None 0 1.16077E-04 None 0 0 None 0 None 0 8.9E-06 0
G/S 17034 Ig-111 80 rs886042475 0.3052 -0.535 1.0 D 0.753 0.735 0.578877614382 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/S 17034 Ig-111 80 rs886042475 0.3052 -0.535 1.0 D 0.753 0.735 0.578877614382 gnomAD-4.0.0 1.17834E-05 None None None None I None 1.33693E-05 8.3439E-05 None 0 0 None 0 0 1.01774E-05 1.09907E-05 0
G/V 17034 Ig-111 80 None 0.8086 None 0.997 D 0.798 0.697 0.934022910283 gnomAD-4.0.0 6.84695E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99969E-07 0 0
G/D 17356 Ig-112 106 rs759091835 0.935 -0.543 1.0 D 0.814 0.7 0.517819333224 gnomAD-2.1.1 1.11E-05 None None None None I None 0 0 None 0 0 None 0 None 0 1.14E-05 2.41429E-04
G/D 17356 Ig-112 106 rs759091835 0.935 -0.543 1.0 D 0.814 0.7 0.517819333224 gnomAD-4.0.0 7.97961E-06 None None None None I None 0 6.37836E-05 None 0 0 None 0 3.72717E-04 5.58091E-06 1.43464E-05 0
G/S 17356 Ig-112 106 rs1300982560 0.6709 -0.417 1.0 D 0.793 0.762 0.495970961353 gnomAD-4.0.0 5.07799E-06 None None None None I None 6.5368E-05 3.18471E-05 None 4.82393E-05 0 None 0 0 2.79048E-06 0 0
G/D 17751 Ig-113 75 None 0.9447 None 1.0 D 0.877 0.613 0.576573652137 gnomAD-4.0.0 1.36888E-06 None None None None I None 0 0 None 3.82995E-05 0 None 0 0 8.9973E-07 0 0
G/R 17751 Ig-113 75 None 0.9392 None 1.0 D 0.901 0.668 0.857950588561 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/A 18052 Ig-114 85 None 0.8952 None 1.0 D 0.723 0.726 0.564282080094 gnomAD-4.0.0 2.06506E-06 None None None None I None 0 0 None 0 0 None 0 0 2.71118E-06 0 0
G/S 18052 Ig-114 85 None 0.8712 None 1.0 D 0.804 0.733 0.557792573389 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/R 18466 Ig-115 85 rs772677752 0.8428 -0.209 1.0 D 0.913 0.806 0.844311691656 gnomAD-2.1.1 7.66E-05 None None None None I None 0 0 None 2.98864E-04 0 None 0 None 0 1.34645E-04 1.43431E-04
G/R 18466 Ig-115 85 rs772677752 0.8428 -0.209 1.0 D 0.913 0.806 0.844311691656 gnomAD-3.1.2 7.24E-05 None None None None I None 0 0 0 0 0 None 0 0 1.6186E-04 0 0
G/R 18466 Ig-115 85 rs772677752 0.8428 -0.209 1.0 D 0.913 0.806 0.844311691656 gnomAD-4.0.0 5.28844E-05 None None None None I None 0 0 None 2.38745E-04 0 None 4.70559E-05 0 5.94238E-05 0 8.04842E-05
G/A 18771 Ig-116 84 None 0.7267 None 1.0 D 0.779 0.801 0.551344072312 gnomAD-4.0.0 1.63586E-06 None None None None I None 0 0 None 0 0 None 0 0 2.93681E-06 0 0
G/R 19170 Ig-117 76 rs750947988 0.7544 -0.217 1.0 D 0.897 0.644 0.624805822903 gnomAD-2.1.1 4.31E-05 None None None None I None 0 1.99317E-04 None 0 0 None 0 None 0 1.57E-05 4.23729E-04
G/R 19170 Ig-117 76 rs750947988 0.7544 -0.217 1.0 D 0.897 0.644 0.624805822903 gnomAD-3.1.2 1.32E-05 None None None None I None 0 1.31234E-04 0 0 0 None 0 0 0 0 0
G/R 19170 Ig-117 76 rs750947988 0.7544 -0.217 1.0 D 0.897 0.644 0.624805822903 gnomAD-4.0.0 3.10093E-06 None None None None I None 0 0 None 0 0 None 0 0 3.39155E-06 0 1.60282E-05
G/A 19466 Ig-118 76 rs201922910 0.8238 -0.001 1.0 D 0.612 0.565 None gnomAD-2.1.1 1.57206E-04 None None None None I None 0 8.49E-05 None 0 0 None 0 None 0 3.12901E-04 1.4041E-04
G/A 19466 Ig-118 76 rs201922910 0.8238 -0.001 1.0 D 0.612 0.565 None gnomAD-3.1.2 1.70976E-04 None None None None I None 4.83E-05 1.31079E-04 0 0 0 None 0 0 3.2351E-04 0 0
G/A 19466 Ig-118 76 rs201922910 0.8238 -0.001 1.0 D 0.612 0.565 None gnomAD-4.0.0 2.4358E-04 None None None None I None 5.34045E-05 1.33418E-04 None 0 0 None 0 0 3.15342E-04 0 1.44138E-04
G/D 19466 Ig-118 76 None 0.9731 None 1.0 D 0.805 0.525 0.63623802299 gnomAD-4.0.0 6.8429E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.1595E-05 0
G/S 19466 Ig-118 76 None 0.7792 None 1.0 D 0.767 0.556 0.579890812634 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/D 19864 Ig-119 75 rs763969580 0.9455 -0.387 1.0 D 0.85 0.678 0.609467651227 gnomAD-2.1.1 8.07E-06 None None None None I None 0 0 None 0 1.11719E-04 None 0 None 0 0 0
G/D 19864 Ig-119 75 rs763969580 0.9455 -0.387 1.0 D 0.85 0.678 0.609467651227 gnomAD-3.1.2 1.32E-05 None None None None I None 0 6.55E-05 0 0 0 None 0 0 1.47E-05 0 0
G/D 19864 Ig-119 75 rs763969580 0.9455 -0.387 1.0 D 0.85 0.678 0.609467651227 gnomAD-4.0.0 7.43885E-06 None None None None I None 0 1.66856E-05 None 0 2.23284E-04 None 0 0 8.47778E-07 0 0
G/C 20158 Ig-120 79 rs375009570 0.8511 -0.733 1.0 D 0.818 0.657 None gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
G/C 20158 Ig-120 79 rs375009570 0.8511 -0.733 1.0 D 0.818 0.657 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/C 20158 Ig-120 79 rs375009570 0.8511 -0.733 1.0 D 0.818 0.657 None gnomAD-4.0.0 8.05902E-06 None None None None I None 0 0 None 0 0 None 0 0 1.01738E-05 0 1.60154E-05
G/D 20158 Ig-120 79 None 0.9068 None 1.0 D 0.861 0.637 0.617803836188 gnomAD-4.0.0 1.36882E-06 None None None None I None 2.99007E-05 0 None 0 0 None 0 0 8.99664E-07 0 0
G/S 20158 Ig-120 79 rs375009570 0.5379 -0.361 1.0 D 0.807 0.622 0.541557034822 gnomAD-2.1.1 2.42E-05 None None None None I None 0 2.9E-05 None 0 0 None 3.27E-05 None 0 3.56E-05 0
G/S 20158 Ig-120 79 rs375009570 0.5379 -0.361 1.0 D 0.807 0.622 0.541557034822 gnomAD-3.1.2 1.97E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 2.94E-05 0 0
G/S 20158 Ig-120 79 rs375009570 0.5379 -0.361 1.0 D 0.807 0.622 0.541557034822 gnomAD-4.0.0 2.16974E-05 None None None None I None 1.33572E-05 3.33611E-05 None 0 8.92618E-05 None 0 0 2.11955E-05 2.19746E-05 1.60154E-05
G/E 20556 Ig-121 78 rs1199461867 0.9699 -0.486 1.0 D 0.855 0.693 0.704066427429 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
G/E 20556 Ig-121 78 rs1199461867 0.9699 -0.486 1.0 D 0.855 0.693 0.704066427429 gnomAD-4.0.0 3.18535E-06 None None None None I None 0 0 None 0 0 None 0 0 5.72082E-06 0 0
G/R 20851 Ig-122 83 None 0.9924 None 1.0 D 0.862 0.679 0.814518163516 gnomAD-4.0.0 1.59195E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85914E-06 0 0
G/V 21253 Ig-123 77 rs770861395 0.8798 -0.023 1.0 D 0.872 0.739 0.759615262451 gnomAD-2.1.1 3.19E-05 None None None None I None 1.14863E-04 0 None 0 0 None 0 None 0 0 0
G/V 21253 Ig-123 77 rs770861395 0.8798 -0.023 1.0 D 0.872 0.739 0.759615262451 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
G/V 21253 Ig-123 77 rs770861395 0.8798 -0.023 1.0 D 0.872 0.739 0.759615262451 gnomAD-4.0.0 6.58033E-06 None None None None I None 2.41523E-05 0 None 0 0 None 0 0 0 0 0
G/A 21546 Ig-124 78 None 0.5377 None 0.949 D 0.469 0.466 0.422160833541 gnomAD-4.0.0 1.59653E-06 None None None None I None 5.69022E-05 0 None 0 0 None 0 0 0 0 0
G/R 21546 Ig-124 78 None 0.8437 None 1.0 D 0.855 0.507 0.644839269284 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
G/D 21943 Ig-125 78 None 0.9592 None 1.0 D 0.803 0.789 0.496628014799 gnomAD-4.0.0 7.15228E-07 None None None None I None 0 0 None 0 0 None 0 0 9.27895E-07 0 0
G/D 22341 Ig-126 77 rs2047417746 0.8893 None 1.0 D 0.869 0.849 0.571380689955 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/D 22341 Ig-126 77 rs2047417746 0.8893 None 1.0 D 0.869 0.849 0.571380689955 gnomAD-4.0.0 6.57687E-06 None None None None I None 2.41383E-05 0 None 0 0 None 0 0 0 0 0
G/S 22341 Ig-126 77 rs554588683 0.536 -0.122 1.0 D 0.817 0.837 0.501559347837 gnomAD-2.1.1 8.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
G/S 22341 Ig-126 77 rs554588683 0.536 -0.122 1.0 D 0.817 0.837 0.501559347837 gnomAD-4.0.0 1.0952E-05 None None None None I None 0 0 None 0 0 None 0 0 1.25961E-05 0 3.31532E-05
G/D 23027 Ig-128 78 rs780975029 0.9147 None 1.0 D 0.853 0.748 0.603824409933 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/R 23422 Ig-129 78 rs780170483 0.8825 -0.465 1.0 D 0.901 0.793 0.842722146577 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 0 0
G/R 23422 Ig-129 78 rs780170483 0.8825 -0.465 1.0 D 0.901 0.793 0.842722146577 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.56E-05 0 0 0 None 0 0 0 0 0
G/R 23422 Ig-129 78 rs780170483 0.8825 -0.465 1.0 D 0.901 0.793 0.842722146577 gnomAD-4.0.0 6.57609E-06 None None None None I None 0 6.55566E-05 None 0 0 None 0 0 0 0 0
G/E 23713 Ig-130 77 None 0.9564 None 0.997 D 0.806 0.792 0.658074552805 gnomAD-4.0.0 1.59226E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8594E-06 0 0
G/A 24109 Ig-131 81 rs1165671355 0.8575 0.056 0.995 D 0.625 0.732 0.581024980495 gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
G/A 24109 Ig-131 81 rs1165671355 0.8575 0.056 0.995 D 0.625 0.732 0.581024980495 gnomAD-4.0.0 4.79388E-06 None None None None I None 0 0 None 0 0 None 0 0 8.61307E-06 0 0
G/D 24506 Ig-132 76 rs567446185 0.9456 -0.053 1.0 D 0.89 0.724 0.599588325989 gnomAD-2.1.1 1.39602E-04 None None None None I None 0 0 None 0 1.85452E-03 None 6.55E-05 None 0 0 1.40924E-04
G/D 24506 Ig-132 76 rs567446185 0.9456 -0.053 1.0 D 0.89 0.724 0.599588325989 gnomAD-3.1.2 4.6E-05 None None None None I None 0 0 0 0 1.35606E-03 None 0 0 0 0 0
G/D 24506 Ig-132 76 rs567446185 0.9456 -0.053 1.0 D 0.89 0.724 0.599588325989 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 1E-03 0 None None None 0 None
G/D 24506 Ig-132 76 rs567446185 0.9456 -0.053 1.0 D 0.89 0.724 0.599588325989 gnomAD-4.0.0 3.40928E-05 None None None None I None 0 0 None 0 9.15465E-04 None 0 0 0 4.39551E-05 1.60097E-04
G/D 24795 Ig-133 80 rs1708265483 0.9016 None 1.0 D 0.863 0.704 0.580736977688 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
G/D 24795 Ig-133 80 rs1708265483 0.9016 None 1.0 D 0.863 0.704 0.580736977688 gnomAD-4.0.0 6.57661E-06 None None None None I None 0 6.5505E-05 None 0 0 None 0 0 0 0 0
G/S 24795 Ig-133 80 None 0.4827 None 1.0 D 0.809 0.645 0.538005241053 gnomAD-4.0.0 1.59205E-06 None None None None I None 5.65995E-05 0 None 0 0 None 0 0 0 0 0
G/A 25191 Ig-134 81 rs767718233 0.6646 -0.57 0.865 D 0.548 0.755 0.457106177737 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/A 25191 Ig-134 81 rs767718233 0.6646 -0.57 0.865 D 0.548 0.755 0.457106177737 gnomAD-4.0.0 2.05318E-06 None None None None I None 0 0 None 0 0 None 0 0 0 3.47834E-05 0
G/E 25191 Ig-134 81 None 0.9228 -1.291 0.978 D 0.783 0.752 0.622375070377 gnomAD-2.1.1 2.15E-05 None None None None I None 0 0 None 0 0 None 9.81E-05 None 0 2.35E-05 0
G/E 25191 Ig-134 81 None 0.9228 -1.291 0.978 D 0.783 0.752 0.622375070377 gnomAD-3.1.2 2.63E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 4.14422E-04 0
G/E 25191 Ig-134 81 None 0.9228 -1.291 0.978 D 0.783 0.752 0.622375070377 gnomAD-4.0.0 2.16956E-05 None None None None I None 0 0 None 0 0 None 0 0 1.86502E-05 1.31761E-04 1.6021E-05
G/R 25191 Ig-134 81 rs763964097 0.8811 -0.437 0.175 D 0.506 0.752 0.631501200734 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/R 25191 Ig-134 81 rs763964097 0.8811 -0.437 0.175 D 0.506 0.752 0.631501200734 gnomAD-4.0.0 1.59226E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43291E-05 0
G/V 25191 Ig-134 81 rs767718233 0.949 -0.438 0.175 D 0.509 0.729 0.628213846089 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
G/V 25191 Ig-134 81 rs767718233 0.949 -0.438 0.175 D 0.509 0.729 0.628213846089 gnomAD-4.0.0 4.10636E-06 None None None None I None 0 0 None 0 2.52781E-05 None 0 0 4.49792E-06 0 0
G/R 25588 Ig-135 75 rs1275050402 0.8665 0.09 0.957 D 0.783 0.778 0.817325593767 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
G/R 25588 Ig-135 75 rs1275050402 0.8665 0.09 0.957 D 0.783 0.778 0.817325593767 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/R 25588 Ig-135 75 rs1275050402 0.8665 0.09 0.957 D 0.783 0.778 0.817325593767 gnomAD-4.0.0 2.5636E-06 None None None None I None 0 0 None 0 0 None 0 0 4.78863E-06 0 0
G/D 26273 Ig-137 81 None 0.9731 None 0.976 D 0.779 0.788 0.475430695062 gnomAD-4.0.0 1.60977E-06 None None None None I None 0 0 None 4.85767E-05 0 None 0 0 0 0 0
G/E 26670 Ig-138 77 None 0.9313 None 1.0 D 0.849 0.832 0.664487949213 gnomAD-4.0.0 2.40065E-06 None None None None I None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
G/D 26959 Ig-139 80 rs768259414 0.9261 -0.278 1.0 D 0.799 0.781 0.626855883447 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
G/D 26959 Ig-139 80 rs768259414 0.9261 -0.278 1.0 D 0.799 0.781 0.626855883447 gnomAD-4.0.0 1.36854E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79905E-06 0 0
G/V 27356 Ig-140 79 rs757116538 0.9549 0.013 1.0 D 0.832 0.642 0.867590122208 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/V 27356 Ig-140 79 rs757116538 0.9549 0.013 1.0 D 0.832 0.642 0.867590122208 gnomAD-4.0.0 3.18257E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.86541E-05 0
G/C 27753 Ig-141 78 None 0.8295 None 1.0 D 0.819 0.709 0.883539022815 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
G/V 27753 Ig-141 78 None 0.9206 None 1.0 D 0.849 0.72 0.918809862971 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/R 28042 Ig-142 80 None 0.895 None 1.0 D 0.821 0.684 0.824278285417 gnomAD-4.0.0 1.5921E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43324E-05 0
G/S 28437 Ig-143 80 rs757770952 0.7373 -0.29 1.0 D 0.811 0.671 0.581344535356 gnomAD-2.1.1 4.03E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
G/S 28437 Ig-143 80 rs757770952 0.7373 -0.29 1.0 D 0.811 0.671 0.581344535356 gnomAD-3.1.2 2.63E-05 None None None None I None 0 1.96515E-04 0 0 0 None 0 0 0 0 4.77555E-04
G/S 28437 Ig-143 80 rs757770952 0.7373 -0.29 1.0 D 0.811 0.671 0.581344535356 gnomAD-4.0.0 7.4373E-06 None None None None I None 1.33504E-05 8.33722E-05 None 0 0 None 0 0 4.23821E-06 0 1.60138E-05
S/G 28832 Ig-144 78 rs2154158012 0.0582 None None N 0.123 0.138 0.110078149338 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/G 28832 Ig-144 78 rs2154158012 0.0582 None None N 0.123 0.138 0.110078149338 gnomAD-4.0.0 2.02957E-06 None None None None I None 0 0 None 0 0 None 0 0 2.40981E-06 0 0
S/N 28832 Ig-144 78 rs747031060 0.0673 -0.006 None N 0.124 0.107 0.152612264143 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 5.57E-05 None 3.27E-05 None 0 0 0
S/N 28832 Ig-144 78 rs747031060 0.0673 -0.006 None N 0.124 0.107 0.152612264143 gnomAD-4.0.0 1.59145E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43332E-05 0
S/T 28832 Ig-144 78 rs747031060 0.0971 -0.029 0.012 N 0.351 0.116 0.16115917748 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
S/T 28832 Ig-144 78 rs747031060 0.0971 -0.029 0.012 N 0.351 0.116 0.16115917748 gnomAD-4.0.0 1.59145E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02425E-05
G/D 29124 Ig-145 80 None 0.833 None 1.0 D 0.853 0.768 0.53586618445 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/R 29520 Ig-146 77 None 0.9487 None 1.0 D 0.889 0.723 0.735079807728 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/D 29919 Ig-147 78 rs759930753 0.7509 None 1.0 D 0.872 0.764 0.562917172789 gnomAD-4.0.0 4.10828E-06 None None None None I None 0 0 None 0 0 None 0 0 5.4008E-06 0 0
C/R 30211 Ig-148 80 rs1329290797 0.539 0.077 0.241 N 0.479 0.207 0.399889258716 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
C/R 30211 Ig-148 80 rs1329290797 0.539 0.077 0.241 N 0.479 0.207 0.399889258716 gnomAD-4.0.0 1.59183E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85889E-06 0 0
C/Y 30211 Ig-148 80 None 0.4007 None 0.061 N 0.425 0.216 0.400033932507 gnomAD-4.0.0 2.73727E-06 None None None None I None 0 0 None 0 0 None 0 0 3.59817E-06 0 0
G/A 30606 Ig-149 75 None 0.6078 None 1.0 D 0.761 0.697 0.55046033382 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
G/C 30606 Ig-149 75 rs773344105 0.8348 -0.531 1.0 D 0.851 0.743 0.686373814236 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.95E-06 0
G/R 30606 Ig-149 75 None 0.8967 None 1.0 D 0.902 0.741 0.624848976157 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
G/V 30606 Ig-149 75 None 0.9358 None 1.0 D 0.871 0.662 0.723075696567 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/A 31003 Ig-150 77 rs1698144956 0.5054 None 1.0 D 0.755 0.795 0.536709800451 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/A 31003 Ig-150 77 rs1698144956 0.5054 None 1.0 D 0.755 0.795 0.536709800451 gnomAD-4.0.0 2.47872E-06 None None None None I None 0 0 None 0 0 None 0 0 1.69519E-06 0 3.20205E-05
G/S 31003 Ig-150 77 rs765552665 0.3465 0.007 1.0 D 0.817 0.755 0.476676017676 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/C 31295 Ig-151 78 rs1235271231 0.639 -0.561 1.0 D 0.834 0.733 0.898243142732 gnomAD-2.1.1 4.02E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
G/C 31295 Ig-151 78 rs1235271231 0.639 -0.561 1.0 D 0.834 0.733 0.898243142732 gnomAD-4.0.0 1.5918E-06 None None None None I None 0 2.28655E-05 None 0 0 None 0 0 0 0 0
G/D 31295 Ig-151 78 rs1211735152 0.8077 -0.502 0.898 D 0.546 0.612 0.546217525997 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/D 31295 Ig-151 78 rs1211735152 0.8077 -0.502 0.898 D 0.546 0.612 0.546217525997 gnomAD-4.0.0 4.77544E-06 None None None None I None 5.65675E-05 0 None 0 0 None 0 0 2.85785E-06 1.43271E-05 0
G/R 31295 Ig-151 78 rs1235271231 0.8021 -0.131 1.0 D 0.865 0.736 0.876500024658 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
G/R 31295 Ig-151 78 rs1235271231 0.8021 -0.131 1.0 D 0.865 0.736 0.876500024658 gnomAD-4.0.0 1.5918E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85781E-06 0 0
G/R 31695 Ig-152 75 rs376403373 0.9799 0.042 1.0 D 0.909 0.824 0.79156988546 gnomAD-2.1.1 5.36E-05 None None None None I None 1.6533E-04 0 None 0 1.02428E-04 None 3.28E-05 None 0 4.7E-05 2.81136E-04
G/R 31695 Ig-152 75 rs376403373 0.9799 0.042 1.0 D 0.909 0.824 0.79156988546 gnomAD-3.1.2 1.05152E-04 None None None None I None 2.41394E-04 6.55E-05 0 0 0 None 0 0 7.35E-05 0 0
G/R 31695 Ig-152 75 rs376403373 0.9799 0.042 1.0 D 0.909 0.824 0.79156988546 gnomAD-4.0.0 8.55507E-05 None None None None I None 2.00315E-04 1.66722E-05 None 0 6.683E-05 None 0 0 9.4973E-05 2.19722E-05 8.00666E-05
G/D 32092 Ig-153 76 rs772540419 0.9335 -0.722 1.0 D 0.846 0.628 0.585653999902 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 0 None 1.30727E-04 None 0 0 0
G/D 32092 Ig-153 76 rs772540419 0.9335 -0.722 1.0 D 0.846 0.628 0.585653999902 gnomAD-4.0.0 7.95793E-06 None None None None I None 0 0 None 0 0 None 0 0 0 7.16414E-05 0
G/R 32092 Ig-153 76 None 0.878 None 1.0 D 0.861 0.667 0.770659404396 gnomAD-4.0.0 3.18308E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 6.0507E-05
G/A 32386 Ig-154 80 rs750418991 0.5414 0.008 0.984 D 0.615 0.79 0.519241965532 gnomAD-2.1.1 3.62E-05 None None None None I None 0 0 None 0 0 None 2.94195E-04 None 0 0 0
G/A 32386 Ig-154 80 rs750418991 0.5414 0.008 0.984 D 0.615 0.79 0.519241965532 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 0 4.14422E-04 0
G/A 32386 Ig-154 80 rs750418991 0.5414 0.008 0.984 D 0.615 0.79 0.519241965532 gnomAD-4.0.0 2.16914E-05 None None None None I None 0 0 None 0 0 None 0 0 0 3.8437E-04 0
G/R 32386 Ig-154 80 rs758534800 0.916 -0.061 0.856 D 0.599 0.745 0.68704070261 gnomAD-2.1.1 4.42E-05 None None None None I None 0 2.9E-05 None 0 5.56E-05 None 3.27E-05 None 0 7.11E-05 0
G/R 32386 Ig-154 80 rs758534800 0.916 -0.061 0.856 D 0.599 0.745 0.68704070261 gnomAD-3.1.2 5.92E-05 None None None None I None 7.24E-05 6.55E-05 0 0 0 None 0 0 4.41E-05 4.14422E-04 0
G/R 32386 Ig-154 80 rs758534800 0.916 -0.061 0.856 D 0.599 0.745 0.68704070261 gnomAD-4.0.0 3.9044E-05 None None None None I None 6.67682E-05 5.00067E-05 None 0 2.22767E-05 None 0 0 4.23837E-05 3.29453E-05 1.60113E-05
G/V 32386 Ig-154 80 None 0.9237 None 0.998 D 0.779 0.763 0.776871967568 gnomAD-4.0.0 6.84273E-07 None None None None I None 2.98864E-05 0 None 0 0 None 0 0 0 0 0
G/R 33180 Ig-156 80 None 0.9757 None 1.0 D 0.87 0.773 0.777805402551 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/A 33277 Ig-157 75 rs397517781 0.9011 -0.484 1.0 D 0.763 0.813 None gnomAD-2.1.1 4.19E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.21E-06 0
G/A 33277 Ig-157 75 rs397517781 0.9011 -0.484 1.0 D 0.763 0.813 None gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/A 33277 Ig-157 75 rs397517781 0.9011 -0.484 1.0 D 0.763 0.813 None gnomAD-4.0.0 8.15334E-06 None None None None I None 0 0 None 0 0 None 0 0 1.11266E-05 0 0
G/E 33277 Ig-157 75 rs397517781 0.9779 -0.752 1.0 D 0.847 0.797 0.787362342877 gnomAD-2.1.1 9.12967E-04 None None None None I None 0 3.03E-05 None 0 0 None 7.64115E-03 None 0 9.21E-06 0
G/E 33277 Ig-157 75 rs397517781 0.9779 -0.752 1.0 D 0.847 0.797 0.787362342877 gnomAD-3.1.2 2.56508E-04 None None None None I None 0 0 0 0 0 None 0 0 0 7.87075E-03 4.78011E-04
G/E 33277 Ig-157 75 rs397517781 0.9779 -0.752 1.0 D 0.847 0.797 0.787362342877 1000 genomes 1.79712E-03 None None None None I None 0 0 None None 0 0 None None None 9.2E-03 None
G/E 33277 Ig-157 75 rs397517781 0.9779 -0.752 1.0 D 0.847 0.797 0.787362342877 gnomAD-4.0.0 4.48402E-04 None None None None I None 0 1.71145E-05 None 0 0 None 0 1.67056E-04 2.5677E-06 7.85555E-03 3.24602E-04
G/A 33577 Ig-158 82 None 0.9044 None 0.999 D 0.759 0.795 0.678929657206 gnomAD-4.0.0 4.27469E-06 None None None None I None 0 0 None 0 0 None 0 0 5.53618E-06 0 0
G/E 33577 Ig-158 82 rs1266341288 0.9892 None 1.0 D 0.841 0.76 0.803714294873 gnomAD-4.0.0 7.12449E-07 None None None None I None 0 0 None 0 0 None 0 0 9.22696E-07 0 0
G/V 33577 Ig-158 82 rs1266341288 0.9854 -0.135 1.0 D 0.841 0.806 0.873585393695 gnomAD-2.1.1 4.84E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 2.06101E-04
G/V 33577 Ig-158 82 rs1266341288 0.9854 -0.135 1.0 D 0.841 0.806 0.873585393695 gnomAD-4.0.0 2.84979E-06 None None None None I None 3.16536E-05 2.69107E-05 None 0 0 None 0 0 9.22696E-07 0 1.73172E-05
G/E 33676 Ig-159 81 rs368894429 0.9959 -0.751 1.0 D 0.834 0.755 None gnomAD-2.1.1 8.04E-06 None None None None I None 1.29199E-04 0 None 0 0 None 0 None 0 0 0
G/E 33676 Ig-159 81 rs368894429 0.9959 -0.751 1.0 D 0.834 0.755 None gnomAD-3.1.2 1.97E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 0 0 0
G/E 33676 Ig-159 81 rs368894429 0.9959 -0.751 1.0 D 0.834 0.755 None gnomAD-4.0.0 1.97138E-05 None None None None I None 7.23764E-05 0 None 0 0 None 0 0 0 0 0
G/R 33676 Ig-159 81 rs762614257 0.9942 -0.359 1.0 D 0.865 0.769 0.866166787405 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
G/D 34216 Ig-160 80 None 0.9363 None 1.0 D 0.851 0.803 0.52133269049 gnomAD-4.0.0 1.36835E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79883E-06 0 0
G/S 34216 Ig-160 80 rs1332571612 0.702 -0.352 1.0 D 0.796 0.75 0.458374381611 gnomAD-2.1.1 1.2E-05 None None None None N None 0 8.7E-05 None 0 0 None 0 None 0 0 0
G/S 34216 Ig-160 80 rs1332571612 0.702 -0.352 1.0 D 0.796 0.75 0.458374381611 gnomAD-4.0.0 4.77328E-06 None None None None N None 0 6.86091E-05 None 0 0 None 0 0 0 0 0
G/A 34340 Ig-161 83 rs1211065675 0.9303 -0.39 1.0 D 0.756 0.813 0.518312163451 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 0 0
G/A 34340 Ig-161 83 rs1211065675 0.9303 -0.39 1.0 D 0.756 0.813 0.518312163451 gnomAD-4.0.0 1.59102E-06 None None None None I None 0 0 None 0 2.773E-05 None 0 0 0 0 0
G/E 34443 Ig-162 81 rs911726592 0.9951 None 1.0 D 0.843 0.849 0.822660018336 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/S 35021 Ig-163 80 rs1454215134 0.8233 None 1.0 D 0.818 0.835 0.526641945673 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 1.01626E-03 None 0 0 None 0 0 0 0 0
G/R 35208 Ig-164 80 rs1688870986 0.8835 None 1.0 D 0.813 0.634 0.618982361579 gnomAD-4.0.0 1.59093E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8575E-06 0 0
G/E 35366 Ig-165 81 None 0.3683 None 1.0 D 0.812 0.763 0.758546266038 gnomAD-4.0.0 1.59094E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85753E-06 0 0
G/R 35366 Ig-165 81 rs1267912817 0.4465 0.092 1.0 D 0.815 0.777 0.828979982932 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
G/R 35366 Ig-165 81 rs1267912817 0.4465 0.092 1.0 D 0.815 0.777 0.828979982932 gnomAD-4.0.0 1.59092E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85755E-06 0 0
G/E 35499 Ig-166 80 rs1211721189 0.7101 None 0.997 D 0.747 0.727 0.731043292528 gnomAD-4.0.0 2.40065E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/R 35499 Ig-166 80 rs779794234 0.8098 None 0.747 D 0.449 0.635 0.707253505956 gnomAD-4.0.0 1.62014E-06 None None None None I None 0 0 None 0 0 None 0 0 2.87887E-06 0 0
G/E 35684 Ig-167 78 None 0.7084 None 0.884 N 0.463 0.497 0.454426139905 gnomAD-4.0.0 1.59186E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85871E-06 0 0
G/R 35684 Ig-167 78 rs761040950 0.8302 -0.283 0.999 N 0.807 0.605 0.59105502098 gnomAD-2.1.1 2.02E-05 None None None None I None 0 0 None 0 0 None 1.64042E-04 None 0 0 0
G/R 35684 Ig-167 78 rs761040950 0.8302 -0.283 0.999 N 0.807 0.605 0.59105502098 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 0 4.13565E-04 0
G/R 35684 Ig-167 78 rs761040950 0.8302 -0.283 0.999 N 0.807 0.605 0.59105502098 gnomAD-4.0.0 1.05364E-05 None None None None I None 0 0 None 0 0 None 0 0 8.47642E-07 1.75805E-04 0
G/S 35781 Ig-168 80 None 0.5809 None 1.0 D 0.794 0.833 0.478222008075 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/V 35978 Ig-169 82 None 0.9409 None 1.0 D 0.835 0.571 0.925565434573 gnomAD-4.0.0 1.20032E-06 None None None -0.948(OBSL1) -0.769(OBSCN) N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.