Structural position:
- Domain Type: Ig
- Aligned Position: 165
- Secondary Structure Element: e
- Secondary Structure Region: β-strand G
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q/E | 88 |
Ig-1 |
83 | None | 0.0887 | None | 0.978 | N | 0.404 | 0.35 | 0.255777322467 | gnomAD-4.0.0 | 1.2004E-06 | None | None | None | -1.409(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31259E-06 | 0 | 0 |
| T/I | 1023 |
Ig-3 |
81 | None | 0.3035 | None | 0.997 | N | 0.669 | 0.389 | 0.536100336011 | gnomAD-4.0.0 | 1.36872E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79879E-06 | 0 | 0 |
| E/K | 1164 |
Ig-4 |
83 | None | 0.7306 | None | 0.998 | N | 0.653 | 0.534 | 0.372268306217 | gnomAD-4.0.0 | 1.59081E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| E/V | 1164 |
Ig-4 |
83 | None | 0.7302 | None | 1.0 | N | 0.724 | 0.729 | 0.588653130956 | gnomAD-4.0.0 | 1.59078E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8569E-06 | 0 | 0 |
| N/H | 1372 |
Ig-5 |
82 | rs745676502 |
0.4138 | -0.863 | 1.0 | N | 0.713 | 0.433 | 0.352048277211 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 6.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/H | 1372 |
Ig-5 |
82 | rs745676502 |
0.4138 | -0.863 | 1.0 | N | 0.713 | 0.433 | 0.352048277211 | gnomAD-4.0.0 | 3.18168E-06 | None | None | None | None | I | None | 5.65675E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02224E-05 |
| R/G | 1538 |
Ig-6 |
82 | rs766463184 |
0.3166 | -0.551 | 0.117 | N | 0.528 | 0.231 | 0.533325340949 | gnomAD-2.1.1 | 1.6E-05 | None | None | None | None | I | None | 0 | 1.15935E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/G | 1538 |
Ig-6 |
82 | rs766463184 |
0.3166 | -0.551 | 0.117 | N | 0.528 | 0.231 | 0.533325340949 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 1538 |
Ig-6 |
82 | rs766463184 |
0.3166 | -0.551 | 0.117 | N | 0.528 | 0.231 | 0.533325340949 | gnomAD-4.0.0 | 7.68586E-06 | None | None | None | None | I | None | 0 | 1.01726E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/I | 1538 |
Ig-6 |
82 | rs753961168 |
0.2518 | None | 0.484 | N | 0.535 | 0.191 | 0.520110530135 | gnomAD-4.0.0 | 2.05264E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79876E-06 | 1.15945E-05 | 0 |
| T/I | 1785 |
Ig-8 |
83 | rs397517649 |
0.2704 | 0.003 | 0.134 | N | 0.204 | 0.242 | 0.388495093706 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/I | 1785 |
Ig-8 |
83 | rs397517649 |
0.2704 | 0.003 | 0.134 | N | 0.204 | 0.242 | 0.388495093706 | gnomAD-4.0.0 | 6.86515E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| T/R | 1785 |
Ig-8 |
83 | rs397517649 |
0.4352 | -0.344 | 0.988 | N | 0.487 | 0.315 | 0.640464653361 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.45E-05 | None | 0 | None | 0 | 0 | 0 |
| T/R | 1785 |
Ig-8 |
83 | rs397517649 |
0.4352 | -0.344 | 0.988 | N | 0.487 | 0.315 | 0.640464653361 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/R | 1785 |
Ig-8 |
83 | rs397517649 |
0.4352 | -0.344 | 0.988 | N | 0.487 | 0.315 | 0.640464653361 | gnomAD-4.0.0 | 3.10791E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23734E-06 | 0 | 0 |
| V/M | 1920 |
Ig-9 |
80 | rs773719613 |
0.1029 | -0.327 | 0.863 | N | 0.4 | 0.198 | 0.596401026678 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| N/K | 2253 |
Ig-11 |
80 | rs1296864074 |
0.1427 | -0.188 | 0.183 | N | 0.324 | 0.114 | 0.0611884634855 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.09051E-04 | None | 0 | None | 0 | 0 | 0 |
| N/K | 2253 |
Ig-11 |
80 | rs1296864074 |
0.1427 | -0.188 | 0.183 | N | 0.324 | 0.114 | 0.0611884634855 | gnomAD-4.0.0 | 3.18242E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.55247E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Q/K | 2870 |
Ig-18 |
76 | None | 0.0785 | None | 0.826 | N | 0.407 | 0.39 | 0.262662153117 | gnomAD-4.0.0 | 1.59047E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85644E-06 | 0 | 0 |
| Q/L | 2870 |
Ig-18 |
76 | rs372008728 |
0.1452 | 0.177 | 0.959 | N | 0.49 | 0.529 | None | gnomAD-2.1.1 | 7.96E-06 | None | None | None | None | I | None | 0 | 0 | None | 1.9857E-04 | 0 | None | 0 | None | 0 | 0 | 0 |
| Q/L | 2870 |
Ig-18 |
76 | rs372008728 |
0.1452 | 0.177 | 0.959 | N | 0.49 | 0.529 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 2.88184E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/L | 2870 |
Ig-18 |
76 | rs372008728 |
0.1452 | 0.177 | 0.959 | N | 0.49 | 0.529 | None | gnomAD-4.0.0 | 2.47824E-06 | None | None | None | None | I | None | 0 | 0 | None | 1.35108E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 3224 |
Ig-22 |
78 | rs557221911 |
0.5455 | -0.323 | 0.549 | N | 0.489 | 0.184 | 0.231873229951 | gnomAD-2.1.1 | 1.99E-05 | None | None | None | None | I | None | 0 | 8.68E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.76E-05 | 0 |
| R/G | 3224 |
Ig-22 |
78 | rs557221911 |
0.5455 | -0.323 | 0.549 | N | 0.489 | 0.184 | 0.231873229951 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 1.30924E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 3224 |
Ig-22 |
78 | rs557221911 |
0.5455 | -0.323 | 0.549 | N | 0.489 | 0.184 | 0.231873229951 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/G | 3224 |
Ig-22 |
78 | rs557221911 |
0.5455 | -0.323 | 0.549 | N | 0.489 | 0.184 | 0.231873229951 | gnomAD-4.0.0 | 3.71726E-06 | None | None | None | None | I | None | 0 | 8.33139E-05 | None | 0 | 0 | None | 0 | 0 | 8.47502E-07 | 0 | 0 |
| V/I | 3319 |
Ig-23 |
81 | rs375533809 |
0.078 | -0.331 | 0.001 | N | 0.162 | 0.048 | None | gnomAD-2.1.1 | 5.32E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.1673E-04 | 0 |
| V/I | 3319 |
Ig-23 |
81 | rs375533809 |
0.078 | -0.331 | 0.001 | N | 0.162 | 0.048 | None | gnomAD-3.1.2 | 8.54E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.91103E-04 | 0 | 0 |
| V/I | 3319 |
Ig-23 |
81 | rs375533809 |
0.078 | -0.331 | 0.001 | N | 0.162 | 0.048 | None | gnomAD-4.0.0 | 5.01858E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.77959E-05 | 0 | 1.60051E-05 |
| Q/K | 3424 |
Ig-24 |
80 | rs370865998 |
0.0959 | 0.326 | 0.514 | N | 0.345 | 0.3 | None | gnomAD-2.1.1 | 1.42E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.33E-05 | 1.38696E-04 |
| Q/K | 3424 |
Ig-24 |
80 | rs370865998 |
0.0959 | 0.326 | 0.514 | N | 0.345 | 0.3 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| Q/K | 3424 |
Ig-24 |
80 | rs370865998 |
0.0959 | 0.326 | 0.514 | N | 0.345 | 0.3 | None | gnomAD-4.0.0 | 3.03636E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.81382E-05 | 0 | 6.40246E-05 |
| E/K | 3547 |
Ig-25 |
83 | rs761225274 |
0.1735 | 0.576 | None | None | None | 0.211 | None | gnomAD-4.0.0 | 1.58622E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.77872E-04 | 0 | 9.05636E-07 | 1.17819E-05 | 1.67151E-05 |
| E/K | 3740 |
Ig-26 |
81 | rs763042113 |
0.0945 | -0.86 | None | None | None | 0.125 | None | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | I | None | 0 | 2.02887E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 3740 |
Ig-26 |
81 | rs763042113 |
0.0945 | -0.86 | None | None | None | 0.125 | None | gnomAD-4.0.0 | 1.27404E-05 | None | None | None | None | I | None | 0 | 1.60066E-04 | None | 0 | 0 | None | 0 | 0 | 2.86134E-06 | 0 | 0 |
| K/N | 3900 |
Ig-27 |
81 | None | 0.2388 | None | 0.055 | N | 0.335 | 0.192 | None | gnomAD-4.0.0 | 1.59119E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85802E-06 | 0 | 0 |
| E/K | 4019 |
Ig-28 |
82 | None | 0.1299 | None | None | N | 0.198 | 0.113 | None | gnomAD-4.0.0 | 4.77686E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41313E-04 | 2.85791E-06 | 0 | 3.02444E-05 |
| S/N | 4780 |
Ig-30 |
81 | rs147879266 |
0.258 | 0.027 | 0.979 | N | 0.452 | 0.207 | None | gnomAD-2.1.1 | 8.93E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.02627E-03 | None | 1.30787E-04 | None | 0 | 7.82E-06 | 0 |
| S/N | 4780 |
Ig-30 |
81 | rs147879266 |
0.258 | 0.027 | 0.979 | N | 0.452 | 0.207 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 7.70713E-04 | None | 0 | 0 | 1.47E-05 | 6.21633E-04 | 0 |
| S/N | 4780 |
Ig-30 |
81 | rs147879266 |
0.258 | 0.027 | 0.979 | N | 0.452 | 0.207 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| S/N | 4780 |
Ig-30 |
81 | rs147879266 |
0.258 | 0.027 | 0.979 | N | 0.452 | 0.207 | None |
Itoh-Satoh (2002)
| None |
DCM
|
het | None | None | I | Genetic analysis of JP DCM families | None | None | None | None | None | None | None | None | None | None | None |
| S/N | 4780 |
Ig-30 |
81 | rs147879266 |
0.258 | 0.027 | 0.979 | N | 0.452 | 0.207 | None | gnomAD-4.0.0 | 4.39978E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.04794E-03 | None | 0 | 0 | 3.39068E-06 | 1.64712E-04 | 8.00333E-05 |
| S/R | 4780 |
Ig-30 |
81 | rs1574048697 |
0.8306 | None | 0.994 | N | 0.502 | 0.365 | 0.547851268036 | gnomAD-4.0.0 | 1.59164E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77454E-05 | None | 0 | 0 | 0 | 0 | 0 |
| A/G | 4875 |
Ig-31 |
81 | rs369989679 |
0.1902 | -0.866 | 0.78 | D | 0.417 | 0.279 | 0.393006254552 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 3.91674E-04 | None | 0 | None | 0 | 0 | 0 |
| A/G | 4875 |
Ig-31 |
81 | rs369989679 |
0.1902 | -0.866 | 0.78 | D | 0.417 | 0.279 | 0.393006254552 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 9.62649E-04 | None | 0 | 0 | 0 | 0 | 0 |
| A/G | 4875 |
Ig-31 |
81 | rs369989679 |
0.1902 | -0.866 | 0.78 | D | 0.417 | 0.279 | 0.393006254552 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| A/G | 4875 |
Ig-31 |
81 | rs369989679 |
0.1902 | -0.866 | 0.78 | D | 0.417 | 0.279 | 0.393006254552 | gnomAD-4.0.0 | 1.11543E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.90101E-04 | None | 0 | 0 | 0 | 0 | 8.00487E-05 |
| S/G | 4968 |
Ig-32 |
81 | rs762238210 |
0.0883 | None | 0.999 | D | 0.565 | 0.262 | 0.356690202451 | gnomAD-4.0.0 | 1.10435E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35513E-05 | 0 | 1.67403E-05 |
| S/N | 4968 |
Ig-32 |
81 | rs1165201342 |
0.1029 | 0.278 | 0.999 | N | 0.718 | 0.292 | 0.356690202451 | gnomAD-2.1.1 | 4.21E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.19E-06 | 0 |
| S/N | 4968 |
Ig-32 |
81 | rs1165201342 |
0.1029 | 0.278 | 0.999 | N | 0.718 | 0.292 | 0.356690202451 | gnomAD-4.0.0 | 1.62688E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9022E-06 | 0 | 0 |
| S/G | 5062 |
Ig-33 |
82 | rs778610579 |
0.1023 | -0.67 | 0.669 | D | 0.313 | 0.299 | 0.26169431596 | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | I | None | 0 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 1.60527E-04 | 1.56E-05 | 0 |
| S/G | 5062 |
Ig-33 |
82 | rs778610579 |
0.1023 | -0.67 | 0.669 | D | 0.313 | 0.299 | 0.26169431596 | gnomAD-4.0.0 | 1.11529E-05 | None | None | None | None | I | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 5.65099E-05 | 0 | 5.72738E-06 | 0 | 3.0259E-05 |
| S/I | 5062 |
Ig-33 |
82 | rs371687650 |
0.1863 | 0.012 | 0.934 | D | 0.557 | 0.323 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/I | 5062 |
Ig-33 |
82 | rs371687650 |
0.1863 | 0.012 | 0.934 | D | 0.557 | 0.323 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 7.24E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/I | 5062 |
Ig-33 |
82 | rs371687650 |
0.1863 | 0.012 | 0.934 | D | 0.557 | 0.323 | None | gnomAD-4.0.0 | 6.20027E-06 | None | None | None | None | I | None | 1.06789E-04 | 1.66744E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60179E-05 |
| S/N | 5062 |
Ig-33 |
82 | rs371687650 |
0.1306 | -0.213 | 0.012 | D | 0.218 | 0.224 | None | gnomAD-2.1.1 | 7.86E-05 | None | None | None | None | I | None | 0 | 2.83E-05 | None | 1.16234E-03 | 0 | None | 0 | None | 0 | 5.48E-05 | 2.81452E-04 |
| S/N | 5062 |
Ig-33 |
82 | rs371687650 |
0.1306 | -0.213 | 0.012 | D | 0.218 | 0.224 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 1.44009E-03 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 5062 |
Ig-33 |
82 | rs371687650 |
0.1306 | -0.213 | 0.012 | D | 0.218 | 0.224 | None | gnomAD-4.0.0 | 3.03813E-05 | None | None | None | None | I | None | 0 | 1.66744E-05 | None | 9.80127E-04 | 0 | None | 0 | 0 | 1.10256E-05 | 0 | 9.61076E-05 |
| K/N | 5155 |
Ig-34 |
81 | rs1215311775 |
0.4116 | 0.414 | 0.982 | N | 0.686 | 0.335 | 0.218845423259 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| K/N | 5155 |
Ig-34 |
81 | rs1215311775 |
0.4116 | 0.414 | 0.982 | N | 0.686 | 0.335 | 0.218845423259 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/N | 5155 |
Ig-34 |
81 | rs1215311775 |
0.4116 | 0.414 | 0.982 | N | 0.686 | 0.335 | 0.218845423259 | gnomAD-4.0.0 | 4.35866E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.95812E-06 | 0 | 0 |
| K/R | 5155 |
Ig-34 |
81 | rs727504207 |
0.082 | None | 0.046 | N | 0.235 | 0.219 | 0.239901079897 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/N | 5248 |
Ig-35 |
81 | rs2080939542 |
0.138 | None | 0.959 | N | 0.288 | 0.193 | 0.247872288689 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 5248 |
Ig-35 |
81 | rs2080939542 |
0.138 | None | 0.959 | N | 0.288 | 0.193 | 0.247872288689 | gnomAD-4.0.0 | 6.57056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4699E-05 | 0 | 0 |
| S/N | 5437 |
Ig-37 |
81 | rs794727755 |
0.1372 | -0.471 | 0.801 | N | 0.341 | 0.323 | 0.235038932564 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| S/N | 5437 |
Ig-37 |
81 | rs794727755 |
0.1372 | -0.471 | 0.801 | N | 0.341 | 0.323 | 0.235038932564 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| S/N | 5437 |
Ig-37 |
81 | rs794727755 |
0.1372 | -0.471 | 0.801 | N | 0.341 | 0.323 | 0.235038932564 | gnomAD-4.0.0 | 1.92194E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62857E-05 | 0 | 0 |
| S/R | 5437 |
Ig-37 |
81 | None | 0.4974 | None | 0.934 | N | 0.475 | 0.276 | 0.475034548194 | gnomAD-4.0.0 | 1.59288E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86131E-06 | 0 | 0 |
| S/N | 5624 |
Ig-39 |
82 | None | 0.0974 | None | 0.004 | N | 0.196 | 0.157 | 0.190952846119 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/T | 5624 |
Ig-39 |
82 | None | 0.0704 | None | 0.002 | N | 0.147 | 0.054 | 0.177238962908 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| S/N | 5717 |
Ig-40 |
81 | rs1484523576 |
0.1249 | -0.406 | 0.837 | D | 0.294 | 0.211 | 0.220303561663 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| S/N | 5717 |
Ig-40 |
81 | rs1484523576 |
0.1249 | -0.406 | 0.837 | D | 0.294 | 0.211 | 0.220303561663 | gnomAD-4.0.0 | 9.5843E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25991E-05 | 0 | 0 |
| I/M | 5810 |
Ig-41 |
81 | rs762158553 |
0.0943 | -0.411 | 0.655 | N | 0.433 | 0.184 | 0.615969100344 | gnomAD-4.0.0 | 7.95641E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85838E-06 | 5.73148E-05 | 0 |
| H/N | 5999 |
Ig-43 |
81 | None | 0.0668 | None | 0.159 | N | 0.217 | 0.113 | 0.183819452728 | gnomAD-4.0.0 | 1.59278E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86203E-06 | 0 | 0 |
| H/Y | 5999 |
Ig-43 |
81 | rs1443927165 |
0.0864 | 0.952 | 0.866 | N | 0.43 | 0.138 | 0.330069100803 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| H/Y | 5999 |
Ig-43 |
81 | rs1443927165 |
0.0864 | 0.952 | 0.866 | N | 0.43 | 0.138 | 0.330069100803 | gnomAD-4.0.0 | 1.59278E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43365E-05 | 0 |
| T/A | 6092 |
Ig-44 |
81 | rs1257068599 |
0.0823 | -0.447 | None | N | 0.102 | 0.053 | 0.110078149338 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 1E-04 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 6092 |
Ig-44 |
81 | rs1257068599 |
0.0823 | -0.447 | None | N | 0.102 | 0.053 | 0.110078149338 | gnomAD-4.0.0 | 1.5929E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02718E-05 |
| T/R | 6092 |
Ig-44 |
81 | None | 0.1709 | None | 0.171 | N | 0.481 | 0.122 | 0.302459207581 | gnomAD-4.0.0 | 1.59304E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02755E-05 |
| T/A | 6186 |
Ig-45 |
82 | None | 0.0707 | None | 0.099 | N | 0.209 | 0.118 | 0.293147016451 | gnomAD-4.0.0 | 1.59141E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85868E-06 | 0 | 0 |
| T/K | 6186 |
Ig-45 |
82 | None | 0.1446 | None | 0.608 | N | 0.428 | 0.26 | 0.404870348458 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 6186 |
Ig-45 |
82 | None | 0.1446 | None | 0.608 | N | 0.428 | 0.26 | 0.404870348458 | gnomAD-4.0.0 | 6.5735E-06 | None | None | None | None | N | None | 2.41289E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/M | 6186 |
Ig-45 |
82 | rs200359082 |
0.0799 | 0.08 | 0.993 | N | 0.476 | 0.272 | None | gnomAD-2.1.1 | 1.14439E-04 | None | None | None | None | N | None | 1.6544E-04 | 2.83E-05 | None | 0 | 5.12E-05 | None | 3.27E-05 | None | 7.19367E-04 | 5.49E-05 | 0 |
| T/M | 6186 |
Ig-45 |
82 | rs200359082 |
0.0799 | 0.08 | 0.993 | N | 0.476 | 0.272 | None | gnomAD-3.1.2 | 9.2E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 1.92827E-04 | None | 6.59134E-04 | 0 | 2.94E-05 | 2.07125E-04 | 0 |
| T/M | 6186 |
Ig-45 |
82 | rs200359082 |
0.0799 | 0.08 | 0.993 | N | 0.476 | 0.272 | None | gnomAD-4.0.0 | 8.98617E-05 | None | None | None | None | N | None | 1.0682E-04 | 1.66739E-05 | None | 0 | 6.68449E-04 | None | 6.24785E-04 | 1.64582E-04 | 4.57741E-05 | 9.88142E-05 | 3.20246E-05 |
| T/R | 6186 |
Ig-45 |
82 | rs200359082 |
0.1164 | -0.055 | 0.916 | N | 0.441 | 0.236 | 0.540472623666 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/R | 6186 |
Ig-45 |
82 | rs200359082 |
0.1164 | -0.055 | 0.916 | N | 0.441 | 0.236 | 0.540472623666 | gnomAD-4.0.0 | 6.84245E-07 | None | None | None | None | N | None | 0 | 2.23604E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 6279 |
Ig-46 |
81 | rs776251068 |
0.3415 | -0.002 | 0.984 | N | 0.625 | 0.265 | 0.463328977263 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 8.95E-06 | 0 |
| S/R | 6279 |
Ig-46 |
81 | rs776251068 |
0.3415 | -0.002 | 0.984 | N | 0.625 | 0.265 | 0.463328977263 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 6279 |
Ig-46 |
81 | rs776251068 |
0.3415 | -0.002 | 0.984 | N | 0.625 | 0.265 | 0.463328977263 | gnomAD-4.0.0 | 3.85259E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.80146E-06 | 1.34279E-05 | 0 |
| V/A | 6372 |
Ig-47 |
81 | rs768519558 |
0.108 | -1.037 | None | N | 0.114 | 0.08 | 0.40528724903 | gnomAD-2.1.1 | 8.13E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| V/A | 6372 |
Ig-47 |
81 | rs768519558 |
0.108 | -1.037 | None | N | 0.114 | 0.08 | 0.40528724903 | gnomAD-3.1.2 | 6.6E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/A | 6372 |
Ig-47 |
81 | rs768519558 |
0.108 | -1.037 | None | N | 0.114 | 0.08 | 0.40528724903 | gnomAD-4.0.0 | 3.86539E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.21838E-06 | 0 | 0 |
| V/G | 6372 |
Ig-47 |
81 | rs768519558 |
0.1679 | -1.358 | 0.012 | N | 0.579 | 0.181 | 0.499281839539 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| V/G | 6372 |
Ig-47 |
81 | rs768519558 |
0.1679 | -1.358 | 0.012 | N | 0.579 | 0.181 | 0.499281839539 | gnomAD-4.0.0 | 1.60117E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.78133E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 6465 |
Ig-48 |
81 | rs796474434 |
0.1331 | None | 0.98 | D | 0.531 | 0.218 | 0.330589388543 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 6561 |
Ig-49 |
81 | rs938213426 |
0.0675 | None | 0.001 | N | 0.127 | 0.122 | 0.270001397563 | gnomAD-4.0.0 | 2.06911E-06 | None | None | None | None | N | None | 0 | 2.2749E-05 | None | 0 | 0 | None | 0 | 0 | 9.04897E-07 | 0 | 1.67023E-05 |
| S/I | 6841 |
Ig-52 |
81 | rs769764362 |
0.192 | 0.049 | 0.771 | N | 0.539 | 0.396 | 0.63759658777 | gnomAD-2.1.1 | 8.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| S/I | 6841 |
Ig-52 |
81 | rs769764362 |
0.192 | 0.049 | 0.771 | N | 0.539 | 0.396 | 0.63759658777 | gnomAD-4.0.0 | 2.748E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.6103E-06 | 0 | 0 |
| S/R | 6841 |
Ig-52 |
81 | None | 0.72 | None | 0.49 | N | 0.427 | 0.276 | 0.28722502521 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/I | 6935 |
Ig-53 |
82 | rs770899268 |
0.1989 | -0.145 | 0.001 | N | 0.191 | 0.132 | 0.241664281697 | gnomAD-2.1.1 | 1.14E-05 | None | None | None | None | I | None | 1.26914E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/I | 6935 |
Ig-53 |
82 | rs770899268 |
0.1989 | -0.145 | 0.001 | N | 0.191 | 0.132 | 0.241664281697 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/I | 6935 |
Ig-53 |
82 | rs770899268 |
0.1989 | -0.145 | 0.001 | N | 0.191 | 0.132 | 0.241664281697 | gnomAD-4.0.0 | 6.54127E-06 | None | None | None | None | I | None | 8.48119E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 7124 |
Ig-55 |
81 | None | 0.0994 | None | 0.01 | N | 0.112 | 0.208 | 0.162503812791 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/M | 7310 |
Ig-57 |
81 | None | 0.1438 | None | 0.56 | N | 0.457 | 0.159 | 0.259761712551 | gnomAD-4.0.0 | 1.59175E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8592E-06 | 0 | 0 |
| R/S | 7310 |
Ig-57 |
81 | None | 0.1822 | None | 0.001 | N | 0.231 | 0.096 | 0.101711395817 | gnomAD-4.0.0 | 1.59178E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85923E-06 | 0 | 0 |
| T/I | 7403 |
Ig-58 |
81 | None | 0.1099 | None | 0.939 | N | 0.447 | 0.213 | 0.493021045079 | gnomAD-4.0.0 | 1.59318E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43451E-05 | 0 |
| T/N | 7403 |
Ig-58 |
81 | rs2078617852 |
0.0972 | None | 0.684 | N | 0.277 | 0.17 | 0.376745185316 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 7403 |
Ig-58 |
81 | rs2078617852 |
0.0972 | None | 0.684 | N | 0.277 | 0.17 | 0.376745185316 | gnomAD-4.0.0 | 6.57402E-06 | None | None | None | None | I | None | 2.41278E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 7499 |
Ig-59 |
81 | rs2078525840 |
0.0918 | None | 0.186 | N | 0.32 | 0.117 | 0.163833314356 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 7499 |
Ig-59 |
81 | rs2078525840 |
0.0918 | None | 0.186 | N | 0.32 | 0.117 | 0.163833314356 | gnomAD-4.0.0 | 5.16597E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.64343E-06 | 0 | 0 |
| T/I | 7499 |
Ig-59 |
81 | None | 0.1663 | None | 0.982 | N | 0.438 | 0.248 | 0.467923293426 | gnomAD-4.0.0 | 3.21709E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.77027E-06 | 0 | 0 |
| K/Q | 7595 |
Ig-60 |
81 | None | 0.1559 | None | 0.998 | N | 0.697 | 0.351 | 0.259272394797 | gnomAD-4.0.0 | 1.59404E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86321E-06 | 0 | 0 |
| K/R | 7595 |
Ig-60 |
81 | rs2078423913 |
0.0862 | None | 0.996 | N | 0.579 | 0.283 | 0.32980341726 | gnomAD-4.0.0 | 1.59412E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86333E-06 | 0 | 0 |
| D/N | 7689 |
Ig-61 |
82 | rs727505052 |
0.0657 | -0.141 | 0.101 | N | 0.278 | 0.068 | 0.144782658237 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 8.28E-05 | 0 | None | 0 | 1.02606E-04 | None | 0 | None | 0 | 0 | 0 |
| D/N | 7689 |
Ig-61 |
82 | rs727505052 |
0.0657 | -0.141 | 0.101 | N | 0.278 | 0.068 | 0.144782658237 | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 7.24E-05 | 1.30941E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| D/N | 7689 |
Ig-61 |
82 | rs727505052 |
0.0657 | -0.141 | 0.101 | N | 0.278 | 0.068 | 0.144782658237 | gnomAD-4.0.0 | 1.93654E-05 | None | None | None | None | N | None | 8.0156E-05 | 3.34717E-05 | None | 0 | 1.12329E-04 | None | 0 | 0 | 1.71034E-06 | 0 | 2.5859E-04 |
| M/I | 7876 |
Ig-63 |
82 | None | 0.277 | None | None | N | 0.137 | 0.193 | 0.53104733087 | gnomAD-4.0.0 | 3.19068E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41663E-04 | 2.86587E-06 | 0 | 0 |
| M/V | 7876 |
Ig-63 |
82 | None | 0.0986 | None | 0.005 | N | 0.188 | 0.106 | 0.52633505579 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| K/N | 7969 |
Ig-64 |
81 | rs1454384580 |
0.2577 | 0.412 | 0.213 | D | 0.367 | 0.101 | 0.15556083564 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| S/P | 8065 |
Ig-65 |
81 | rs2077961175 |
0.6341 | None | 0.106 | N | 0.509 | 0.273 | 0.33440975612 | gnomAD-4.0.0 | 1.59144E-06 | None | None | None | None | I | None | 5.65675E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 8158 |
Ig-66 |
81 | rs551835183 |
0.0957 | -0.164 | 0.801 | N | 0.364 | 0.229 | 0.250579442822 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| S/N | 8158 |
Ig-66 |
81 | rs551835183 |
0.0957 | -0.164 | 0.801 | N | 0.364 | 0.229 | 0.250579442822 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 8158 |
Ig-66 |
81 | rs551835183 |
0.0957 | -0.164 | 0.801 | N | 0.364 | 0.229 | 0.250579442822 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| S/N | 8158 |
Ig-66 |
81 | rs551835183 |
0.0957 | -0.164 | 0.801 | N | 0.364 | 0.229 | 0.250579442822 | gnomAD-4.0.0 | 4.3378E-06 | None | None | None | None | I | None | 1.33312E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08587E-06 | 0 | 0 |
| S/R | 8158 |
Ig-66 |
81 | rs1471384765 |
0.2656 | -0.112 | 0.669 | D | 0.42 | 0.249 | 0.299770980665 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.65E-05 | 0 | 0 |
| S/R | 8158 |
Ig-66 |
81 | rs1471384765 |
0.2656 | -0.112 | 0.669 | D | 0.42 | 0.249 | 0.299770980665 | gnomAD-4.0.0 | 3.18266E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.88267E-05 | 0 | 2.85843E-06 | 0 | 0 |
| Q/H | 8251 |
Ig-67 |
81 | rs1377167368 |
0.1943 | -0.656 | 0.001 | N | 0.159 | 0.16 | 0.259761712551 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Q/H | 8251 |
Ig-67 |
81 | rs1377167368 |
0.1943 | -0.656 | 0.001 | N | 0.159 | 0.16 | 0.259761712551 | gnomAD-4.0.0 | 3.42136E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49772E-06 | 0 | 0 |
| A/E | 8344 |
Ig-68 |
81 | rs748045267 |
0.1777 | -1.103 | 0.747 | N | 0.427 | 0.187 | 0.489243007833 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| A/E | 8344 |
Ig-68 |
81 | rs748045267 |
0.1777 | -1.103 | 0.747 | N | 0.427 | 0.187 | 0.489243007833 | gnomAD-4.0.0 | 1.59253E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86182E-06 | 0 | 0 |
| A/T | 8344 |
Ig-68 |
81 | rs2077751372 |
0.0798 | None | 0.004 | N | 0.247 | 0.096 | 0.171388866994 | gnomAD-4.0.0 | 1.36876E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79943E-06 | 0 | 0 |
| T/S | 8440 |
Ig-69 |
81 | rs778495825 |
0.1008 | 0.069 | 0.001 | N | 0.107 | 0.12 | 0.110078149338 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| T/S | 8440 |
Ig-69 |
81 | rs778495825 |
0.1008 | 0.069 | 0.001 | N | 0.107 | 0.12 | 0.110078149338 | gnomAD-4.0.0 | 1.59543E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43728E-05 | 0 |
| S/C | 8630 |
Ig-71 |
82 | None | 0.2037 | None | 0.977 | N | 0.611 | 0.383 | 0.564651752942 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/R | 8723 |
Ig-72 |
81 | rs1304915212 |
0.496 | None | 0.011 | D | 0.281 | 0.172 | 0.0846915920261 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 8723 |
Ig-72 |
81 | rs1304915212 |
0.496 | None | 0.011 | D | 0.281 | 0.172 | 0.0846915920261 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/I | 8817 |
Ig-73 |
82 | rs1427255919 |
0.166 | -0.281 | None | N | 0.107 | 0.205 | 0.472181857204 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.9E-06 | 0 |
| M/I | 8817 |
Ig-73 |
82 | rs1427255919 |
0.166 | -0.281 | None | N | 0.107 | 0.205 | 0.472181857204 | gnomAD-4.0.0 | 3.18436E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86071E-06 | 1.43316E-05 | 0 |
| M/T | 8817 |
Ig-73 |
82 | rs1469529188 |
0.104 | -0.033 | None | N | 0.154 | 0.123 | 0.400468435593 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| M/T | 8817 |
Ig-73 |
82 | rs1469529188 |
0.104 | -0.033 | None | N | 0.154 | 0.123 | 0.400468435593 | gnomAD-4.0.0 | 9.58085E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25956E-05 | 0 | 0 |
| M/V | 8817 |
Ig-73 |
82 | rs878856898 |
0.0768 | None | None | N | 0.105 | 0.081 | 0.395143324098 | gnomAD-4.0.0 | 1.5918E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85981E-06 | 0 | 0 |
| K/Q | 8910 |
Ig-74 |
81 | rs760765484 |
0.106 | 0.359 | 0.051 | N | 0.205 | 0.117 | 0.192905019026 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/F | 9006 |
Ig-75 |
81 | None | 0.1904 | None | 0.035 | N | 0.385 | 0.318 | 0.630674063255 | gnomAD-4.0.0 | 1.59165E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85873E-06 | 0 | 0 |
| K/N | 9099 |
Ig-76 |
81 | None | 0.3359 | None | 0.22 | D | 0.602 | 0.156 | 0.144782658237 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/R | 9192 |
Ig-77 |
81 | None | 0.0748 | None | 0.001 | N | 0.229 | 0.083 | 0.230578612272 | gnomAD-4.0.0 | 4.7742E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.5754E-06 | 0 | 0 |
| E/A | 9285 |
Ig-78 |
81 | rs1560573999 |
0.1243 | None | 0.007 | N | 0.225 | 0.248 | 0.297718772494 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| E/A | 9285 |
Ig-78 |
81 | rs1560573999 |
0.1243 | None | 0.007 | N | 0.225 | 0.248 | 0.297718772494 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/A | 9285 |
Ig-78 |
81 | rs1560573999 |
0.1243 | None | 0.007 | N | 0.225 | 0.248 | 0.297718772494 | gnomAD-4.0.0 | 6.5722E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4699E-05 | 0 | 0 |
| E/K | 9285 |
Ig-78 |
81 | None | 0.114 | None | 0.549 | N | 0.391 | 0.215 | 0.283761946502 | gnomAD-4.0.0 | 1.60823E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8929E-06 | 0 | 0 |
| S/C | 9381 |
Ig-79 |
81 | rs763983068 |
0.2287 | -0.188 | 0.999 | None | 0.539 | 0.367 | None | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.70532E-04 |
| S/C | 9381 |
Ig-79 |
81 | rs763983068 |
0.2287 | -0.188 | 0.999 | None | 0.539 | 0.367 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| S/C | 9381 |
Ig-79 |
81 | rs763983068 |
0.2287 | -0.188 | 0.999 | None | 0.539 | 0.367 | None | gnomAD-4.0.0 | 1.30878E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.56573E-05 | 0 | 1.61703E-05 | 0 | 1.61129E-05 |
| S/P | 9381 |
Ig-79 |
81 | rs1376908968 |
0.627 | -0.47 | 0.984 | None | 0.48 | 0.473 | 0.396645960531 | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| S/P | 9381 |
Ig-79 |
81 | rs1376908968 |
0.627 | -0.47 | 0.984 | None | 0.48 | 0.473 | 0.396645960531 | gnomAD-4.0.0 | 6.88643E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52487E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 9477 |
Ig-80 |
81 | None | 0.2117 | None | 0.008 | None | 0.258 | 0.192 | 0.301789629655 | gnomAD-4.0.0 | 1.20032E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-05 | 0 | 0 |
| K/R | 9477 |
Ig-80 |
81 | None | 0.0977 | None | 0.722 | None | 0.552 | 0.202 | 0.349647731962 | gnomAD-4.0.0 | 3.18772E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.94118E-04 | 2.85919E-06 | 0 | 0 |
| S/C | 9574 |
Ig-81 |
82 | rs376276989 |
0.2381 | -0.014 | 0.999 | None | 0.487 | 0.504 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/C | 9574 |
Ig-81 |
82 | rs376276989 |
0.2381 | -0.014 | 0.999 | None | 0.487 | 0.504 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 9574 |
Ig-81 |
82 | rs376276989 |
0.2381 | -0.014 | 0.999 | None | 0.487 | 0.504 | None | gnomAD-4.0.0 | 2.02972E-06 | None | None | None | None | I | None | 1.74648E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20489E-06 | 0 | 0 |
| S/F | 9574 |
Ig-81 |
82 | rs376276989 |
0.3057 | None | 0.996 | None | 0.537 | 0.535 | 0.779969046472 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| P/S | 9977 |
Ig-84 |
78 | rs1254687485 |
0.9721 | None | 1.0 | None | 0.686 | 0.329 | 0.206339911435 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 9977 |
Ig-84 |
78 | rs1254687485 |
0.9721 | None | 1.0 | None | 0.686 | 0.329 | 0.206339911435 | gnomAD-4.0.0 | 3.84925E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19031E-06 | 0 | 0 |
| E/D | 13766 |
Ig-87 |
83 | rs575272939 |
0.7019 | -0.87 | 0.999 | N | 0.525 | 0.31 | 0.315609569513 | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.65442E-04 | None | 0 | 0 | 0 |
| E/D | 13766 |
Ig-87 |
83 | rs575272939 |
0.7019 | -0.87 | 0.999 | N | 0.525 | 0.31 | 0.315609569513 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.13736E-04 | 0 |
| E/D | 13766 |
Ig-87 |
83 | rs575272939 |
0.7019 | -0.87 | 0.999 | N | 0.525 | 0.31 | 0.315609569513 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| E/D | 13766 |
Ig-87 |
83 | rs575272939 |
0.7019 | -0.87 | 0.999 | N | 0.525 | 0.31 | 0.315609569513 | gnomAD-4.0.0 | 2.35862E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.96913E-04 | 3.20852E-05 |
| E/K | 13766 |
Ig-87 |
83 | None | 0.8845 | None | 0.999 | N | 0.689 | 0.419 | 0.541194085853 | gnomAD-4.0.0 | 3.42741E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.50322E-06 | 0 | 0 |
| E/Q | 13766 |
Ig-87 |
83 | rs867849913 |
0.6297 | -0.309 | 1.0 | N | 0.669 | 0.367 | 0.441017621159 | gnomAD-2.1.1 | 8.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.12638E-04 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 13766 |
Ig-87 |
83 | rs867849913 |
0.6297 | -0.309 | 1.0 | N | 0.669 | 0.367 | 0.441017621159 | gnomAD-4.0.0 | 2.05645E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.06252E-05 | None | 0 | 0 | 9.00645E-07 | 0 | 0 |
| P/H | 13955 |
Ig-89 |
80 | rs776863726 |
0.6438 | -0.72 | 0.621 | N | 0.512 | 0.258 | 0.443388199986 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/H | 13955 |
Ig-89 |
80 | rs776863726 |
0.6438 | -0.72 | 0.621 | N | 0.512 | 0.258 | 0.443388199986 | gnomAD-4.0.0 | 2.0531E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.80424E-05 | 0 | 0 |
| P/L | 13955 |
Ig-89 |
80 | rs776863726 |
0.396 | None | 0.03 | N | 0.515 | 0.235 | 0.37479162749 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 13955 |
Ig-89 |
80 | rs776863726 |
0.396 | None | 0.03 | N | 0.515 | 0.235 | 0.37479162749 | gnomAD-4.0.0 | 1.86646E-06 | None | None | None | None | N | None | 1.33743E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.49771E-07 | 0 | 1.60689E-05 |
| A/S | 14398 |
Ig-94 |
80 | None | 0.096 | None | 0.007 | N | 0.253 | 0.072 | 0.0954503805726 | gnomAD-4.0.0 | 6.84668E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52309E-05 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 14398 |
Ig-94 |
80 | rs536808297 |
0.0939 | -0.619 | 0.376 | N | 0.563 | 0.08 | 0.173771789658 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 14398 |
Ig-94 |
80 | rs536808297 |
0.0939 | -0.619 | 0.376 | N | 0.563 | 0.08 | 0.173771789658 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| A/T | 14398 |
Ig-94 |
80 | rs536808297 |
0.0939 | -0.619 | 0.376 | N | 0.563 | 0.08 | 0.173771789658 | gnomAD-4.0.0 | 1.86017E-06 | None | None | None | None | N | None | 2.66802E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47965E-07 | 0 | 0 |
| S/N | 14487 |
Ig-95 |
80 | rs770233190 |
0.2988 | -0.183 | 0.994 | D | 0.577 | 0.466 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 14487 |
Ig-95 |
80 | rs770233190 |
0.2988 | -0.183 | 0.994 | D | 0.577 | 0.466 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 14487 |
Ig-95 |
80 | rs770233190 |
0.2988 | -0.183 | 0.994 | D | 0.577 | 0.466 | None | gnomAD-4.0.0 | 2.4796E-05 | None | None | None | None | N | None | 1.33543E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.22155E-05 | 0 | 1.60205E-05 |
| S/R | 14487 |
Ig-95 |
80 | rs2059935679 |
0.6858 | None | 0.998 | D | 0.739 | 0.624 | 0.547512163748 | gnomAD-4.0.0 | 1.59266E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88303E-05 | 0 | 0 | 0 | 0 |
| S/I | 14754 |
Ig-98 |
80 | rs377344521 |
0.2262 | -0.119 | 0.976 | D | 0.711 | 0.343 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/I | 14754 |
Ig-98 |
80 | rs377344521 |
0.2262 | -0.119 | 0.976 | D | 0.711 | 0.343 | None | gnomAD-4.0.0 | 1.2399E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69572E-06 | 0 | 0 |
| S/T | 14754 |
Ig-98 |
80 | rs377344521 |
0.0847 | -0.08 | 0.791 | N | 0.589 | 0.184 | 0.16115917748 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| S/T | 14754 |
Ig-98 |
80 | rs377344521 |
0.0847 | -0.08 | 0.791 | N | 0.589 | 0.184 | 0.16115917748 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/T | 14754 |
Ig-98 |
80 | rs377344521 |
0.0847 | -0.08 | 0.791 | N | 0.589 | 0.184 | 0.16115917748 | gnomAD-4.0.0 | 2.4798E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39143E-06 | 0 | 0 |
| H/Q | 14843 |
Ig-99 |
79 | None | 0.0898 | None | None | N | 0.137 | 0.07 | 0.0482279557977 | gnomAD-4.0.0 | 6.87894E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02402E-07 | 0 | 0 |
| S/F | 14932 |
Ig-100 |
80 | None | 0.4252 | None | 0.999 | N | 0.701 | 0.424 | 0.282575091529 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/E | 15377 |
Ig-105 |
76 | None | 0.0903 | None | 0.08 | N | 0.179 | 0.147 | 0.141422826196 | gnomAD-4.0.0 | 1.36972E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.32218E-05 | 0 |
| Q/K | 15377 |
Ig-105 |
76 | None | 0.0853 | None | 0.285 | N | 0.279 | 0.188 | 0.139678290688 | gnomAD-4.0.0 | 6.84858E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00095E-07 | 0 | 0 |
| Q/R | 15377 |
Ig-105 |
76 | None | 0.111 | None | 0.491 | N | 0.268 | 0.142 | 0.143124449307 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| R/C | 15470 |
Ig-106 |
80 | rs373502448 |
0.5042 | -0.287 | 1.0 | D | 0.741 | 0.629 | None | gnomAD-2.1.1 | 8.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.12982E-04 | None | 0 | None | 0 | 0 | 0 |
| R/C | 15470 |
Ig-106 |
80 | rs373502448 |
0.5042 | -0.287 | 1.0 | D | 0.741 | 0.629 | None | gnomAD-4.0.0 | 1.44039E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.575E-05 | 0 | 0 |
| R/H | 15470 |
Ig-106 |
80 | rs769044716 |
0.1966 | -1.104 | 1.0 | D | 0.756 | 0.504 | None | gnomAD-2.1.1 | 2.04E-05 | None | None | None | None | N | None | 6.5E-05 | 2.94E-05 | None | 0 | 0 | None | 0 | None | 4.67E-05 | 1.81E-05 | 0 |
| R/H | 15470 |
Ig-106 |
80 | rs769044716 |
0.1966 | -1.104 | 1.0 | D | 0.756 | 0.504 | None | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.95E-05 | 0 | 0 |
| R/H | 15470 |
Ig-106 |
80 | rs769044716 |
0.1966 | -1.104 | 1.0 | D | 0.756 | 0.504 | None | gnomAD-4.0.0 | 1.1177E-05 | None | None | None | None | N | None | 2.67795E-05 | 1.67813E-05 | None | 0 | 2.24165E-05 | None | 0 | 0 | 1.1031E-05 | 1.10632E-05 | 0 |
| K/R | 15645 |
Ig-108 |
78 | rs2057766757 |
0.0788 | None | 0.669 | N | 0.401 | 0.177 | 0.411133732114 | gnomAD-4.0.0 | 3.34922E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.83301E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 16043 |
Ig-109 |
76 | None | 0.0808 | None | None | N | 0.133 | 0.072 | 0.0920862733494 | gnomAD-4.0.0 | 1.59361E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.88587E-05 | 0 | 0 | 0 | 0 |
| T/I | 16043 |
Ig-109 |
76 | None | 0.2314 | None | 0.055 | N | 0.515 | 0.194 | 0.434716162284 | gnomAD-4.0.0 | 4.78097E-06 | None | None | None | None | I | None | 0 | 4.57854E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02939E-05 |
| T/R | 16043 |
Ig-109 |
76 | rs2057418334 |
0.1856 | None | 0.055 | N | 0.497 | 0.2 | 0.573444017615 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 16043 |
Ig-109 |
76 | rs2057418334 |
0.1856 | None | 0.055 | N | 0.497 | 0.2 | 0.573444017615 | gnomAD-4.0.0 | 6.58406E-06 | None | None | None | None | I | None | 0 | 6.56513E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 16339 |
Ig-110 |
78 | rs558487304 |
0.2577 | 0.019 | 1.0 | N | 0.731 | 0.379 | 0.351614576976 | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | I | None | 0 | 1.16734E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| R/Q | 16339 |
Ig-110 |
78 | rs558487304 |
0.2577 | 0.019 | 1.0 | N | 0.731 | 0.379 | 0.351614576976 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | I | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 16339 |
Ig-110 |
78 | rs558487304 |
0.2577 | 0.019 | 1.0 | N | 0.731 | 0.379 | 0.351614576976 | gnomAD-4.0.0 | 1.6769E-05 | None | None | None | None | I | None | 2.67609E-05 | 1.00388E-04 | None | 0 | 0 | None | 0 | 0 | 1.35837E-05 | 2.20897E-05 | 1.60524E-05 |
| R/W | 16339 |
Ig-110 |
78 | rs201793958 |
0.615 | -0.399 | 1.0 | D | 0.739 | 0.527 | None | gnomAD-2.1.1 | 1.00704E-04 | None | None | None | None | I | None | 9.52223E-04 | 2.85E-05 | None | 0 | 5.21E-05 | None | 0 | None | 0 | 2.36E-05 | 0 |
| R/W | 16339 |
Ig-110 |
78 | rs201793958 |
0.615 | -0.399 | 1.0 | D | 0.739 | 0.527 | None | gnomAD-3.1.2 | 2.96638E-04 | None | None | None | None | I | None | 8.95233E-04 | 1.97109E-04 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 0 | 4.79846E-04 |
| R/W | 16339 |
Ig-110 |
78 | rs201793958 |
0.615 | -0.399 | 1.0 | D | 0.739 | 0.527 | None | gnomAD-4.0.0 | 5.34041E-05 | None | None | None | None | I | None | 8.83581E-04 | 8.36176E-05 | None | 0 | 0 | None | 0 | 1.64908E-04 | 8.48876E-06 | 0 | 6.41972E-05 |
| S/P | 17035 |
Ig-111 |
81 | None | 0.5966 | None | 0.988 | D | 0.438 | 0.503 | 0.344483371355 | gnomAD-4.0.0 | 1.59388E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77917E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 17357 |
Ig-112 |
107 | None | 0.0759 | None | 0.171 | N | 0.377 | 0.11 | 0.0884992946249 | gnomAD-4.0.0 | 2.91106E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.72681E-06 | 0 | 0 |
| I/V | 17357 |
Ig-112 |
107 | rs773768518 |
0.0603 | 0.027 | None | N | 0.111 | 0.252 | 0.18995819373 | gnomAD-2.1.1 | 5.6E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.15E-05 | 0 |
| I/V | 17357 |
Ig-112 |
107 | rs773768518 |
0.0603 | 0.027 | None | N | 0.111 | 0.252 | 0.18995819373 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 17357 |
Ig-112 |
107 | rs773768518 |
0.0603 | 0.027 | None | N | 0.111 | 0.252 | 0.18995819373 | gnomAD-4.0.0 | 3.92652E-06 | None | None | None | None | I | None | 1.39032E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.37777E-06 | 0 | 0 |
| S/P | 18053 |
Ig-114 |
86 | rs1559718586 |
0.6952 | None | 0.879 | D | 0.514 | 0.334 | 0.239901079897 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.08E-06 | 0 |
| S/P | 18053 |
Ig-114 |
86 | rs1559718586 |
0.6952 | None | 0.879 | D | 0.514 | 0.334 | 0.239901079897 | gnomAD-4.0.0 | 1.61348E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.90156E-06 | 0 | 0 |
| Q/K | 18467 |
Ig-115 |
86 | None | 0.115 | None | 0.997 | N | 0.519 | 0.355 | 0.296329037015 | gnomAD-4.0.0 | 1.60775E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87297E-06 | 0 | 0 |
| T/A | 18772 |
Ig-116 |
85 | rs964263107 |
0.0882 | -0.162 | 0.948 | D | 0.48 | 0.195 | 0.311691414656 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 18772 |
Ig-116 |
85 | rs964263107 |
0.0882 | -0.162 | 0.948 | D | 0.48 | 0.195 | 0.311691414656 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 18772 |
Ig-116 |
85 | rs964263107 |
0.0882 | -0.162 | 0.948 | D | 0.48 | 0.195 | 0.311691414656 | gnomAD-4.0.0 | 1.97254E-05 | None | None | None | None | I | None | 7.23833E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 18772 |
Ig-116 |
85 | rs370118111 |
0.1188 | -0.024 | 0.998 | N | 0.542 | 0.262 | None | gnomAD-2.1.1 | 8.42E-06 | None | None | None | None | I | None | 0 | 6.09E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 18772 |
Ig-116 |
85 | rs370118111 |
0.1188 | -0.024 | 0.998 | N | 0.542 | 0.262 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | I | None | 2.41E-05 | 3.28084E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.44092E-03 |
| T/I | 18772 |
Ig-116 |
85 | rs370118111 |
0.1188 | -0.024 | 0.998 | N | 0.542 | 0.262 | None | gnomAD-4.0.0 | 1.96885E-05 | None | None | None | None | I | None | 1.71057E-05 | 1.39943E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.74581E-04 |
| E/D | 19171 |
Ig-117 |
77 | rs1336572804 |
0.2406 | -0.419 | 0.999 | N | 0.479 | 0.296 | 0.459463830659 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| E/D | 19171 |
Ig-117 |
77 | rs1336572804 |
0.2406 | -0.419 | 0.999 | N | 0.479 | 0.296 | 0.459463830659 | gnomAD-4.0.0 | 3.18854E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72282E-06 | 0 | 0 |
| S/P | 19467 |
Ig-118 |
77 | rs920055688 |
0.7207 | None | 0.984 | N | 0.468 | 0.499 | 0.426084969639 | gnomAD-4.0.0 | 1.36859E-06 | None | None | None | None | I | None | 2.98864E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15953E-05 | 0 |
| S/T | 19467 |
Ig-118 |
77 | rs920055688 |
0.0783 | None | 0.046 | N | 0.211 | 0.077 | 0.208000267992 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 19467 |
Ig-118 |
77 | rs920055688 |
0.0783 | None | 0.046 | N | 0.211 | 0.077 | 0.208000267992 | gnomAD-4.0.0 | 3.7187E-06 | None | None | None | None | I | None | 1.33486E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23846E-06 | 0 | 0 |
| S/L | 19865 |
Ig-119 |
76 | None | 0.107 | None | 0.124 | N | 0.607 | 0.343 | 0.391156786388 | gnomAD-4.0.0 | 1.59307E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02645E-05 |
| S/N | 20159 |
Ig-120 |
80 | rs1005693391 |
0.1085 | None | 0.22 | D | 0.411 | 0.093 | 0.165133752707 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| H/D | 20557 |
Ig-121 |
79 | rs1440800435 |
0.2015 | None | 0.454 | N | 0.491 | 0.316 | 0.317084106153 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/D | 20557 |
Ig-121 |
79 | rs1440800435 |
0.2015 | None | 0.454 | N | 0.491 | 0.316 | 0.317084106153 | gnomAD-4.0.0 | 6.57644E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47106E-05 | 0 | 0 |
| H/R | 20557 |
Ig-121 |
79 | rs1472565206 |
0.1298 | 0.184 | 0.669 | N | 0.341 | 0.263 | 0.263612267334 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| H/R | 20557 |
Ig-121 |
79 | rs1472565206 |
0.1298 | 0.184 | 0.669 | N | 0.341 | 0.263 | 0.263612267334 | gnomAD-4.0.0 | 1.36894E-06 | None | None | None | None | I | None | 2.99061E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99688E-07 | 0 | 0 |
| H/Y | 20557 |
Ig-121 |
79 | rs1440800435 |
0.0879 | None | 0.961 | N | 0.419 | 0.289 | 0.342168650903 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/Y | 20557 |
Ig-121 |
79 | rs1440800435 |
0.0879 | None | 0.961 | N | 0.419 | 0.289 | 0.342168650903 | gnomAD-4.0.0 | 6.57644E-06 | None | None | None | None | I | None | 2.41348E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 21254 |
Ig-123 |
78 | None | 0.282 | None | 0.955 | N | 0.603 | 0.345 | 0.309530620856 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| T/K | 21547 |
Ig-124 |
79 | rs528663658 |
0.1119 | -0.206 | None | N | 0.197 | 0.112 | 0.221734844693 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.3E-05 | None | 0 | 0 | 0 |
| T/K | 21547 |
Ig-124 |
79 | rs528663658 |
0.1119 | -0.206 | None | N | 0.197 | 0.112 | 0.221734844693 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| T/K | 21547 |
Ig-124 |
79 | rs528663658 |
0.1119 | -0.206 | None | N | 0.197 | 0.112 | 0.221734844693 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.21507E-04 | 0 |
| T/P | 21547 |
Ig-124 |
79 | rs1357789824 |
0.3331 | -0.488 | 0.171 | N | 0.463 | 0.14 | 0.255777322467 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.67224E-04 | None | 0 | None | 0 | 0 | 0 |
| T/P | 21547 |
Ig-124 |
79 | rs1357789824 |
0.3331 | -0.488 | 0.171 | N | 0.463 | 0.14 | 0.255777322467 | gnomAD-4.0.0 | 2.05536E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.56163E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 21944 |
Ig-125 |
79 | None | 0.0917 | None | 0.997 | D | 0.625 | 0.423 | 0.495573750707 | gnomAD-4.0.0 | 1.76804E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.16274E-06 | 0 | 0 |
| S/Y | 21944 |
Ig-125 |
79 | None | 0.1994 | None | 0.99 | D | 0.713 | 0.435 | 0.622510390952 | gnomAD-4.0.0 | 1.76804E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.75371E-05 | 0 |
| T/M | 23028 |
Ig-128 |
79 | rs754823057 |
0.0962 | 0.128 | 0.999 | N | 0.642 | 0.346 | 0.716887018219 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.03799E-04 | None | 0 | None | 0 | 3.13E-05 | 0 |
| T/M | 23028 |
Ig-128 |
79 | rs754823057 |
0.0962 | 0.128 | 0.999 | N | 0.642 | 0.346 | 0.716887018219 | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93874E-04 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/M | 23028 |
Ig-128 |
79 | rs754823057 |
0.0962 | 0.128 | 0.999 | N | 0.642 | 0.346 | 0.716887018219 | gnomAD-4.0.0 | 9.30193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.47828E-05 | None | 0 | 0 | 1.01742E-05 | 0 | 1.60262E-05 |
| K/R | 23423 |
Ig-129 |
79 | None | 0.0836 | None | 0.958 | N | 0.56 | 0.339 | 0.330589388543 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 23714 |
Ig-130 |
78 | rs767016969 |
0.2083 | 0.734 | 0.549 | N | 0.361 | 0.248 | 0.268211541103 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66389E-04 |
| E/K | 23714 |
Ig-130 |
78 | rs767016969 |
0.2083 | 0.734 | 0.549 | N | 0.361 | 0.248 | 0.268211541103 | gnomAD-4.0.0 | 6.84398E-06 | None | None | None | None | I | None | 2.98882E-05 | 2.23734E-05 | None | 0 | 0 | None | 0 | 0 | 5.39758E-06 | 0 | 3.31466E-05 |
| E/D | 24796 |
Ig-133 |
81 | None | 0.1438 | None | 0.822 | N | 0.436 | 0.232 | 0.386071988338 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/Q | 24796 |
Ig-133 |
81 | None | 0.1299 | None | 0.97 | N | 0.456 | 0.332 | 0.3691244813 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/A | 25192 |
Ig-134 |
82 | None | 0.167 | -0.644 | 0.999 | N | 0.71 | 0.625 | 0.557519804684 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/A | 25192 |
Ig-134 |
82 | None | 0.167 | -0.644 | 0.999 | N | 0.71 | 0.625 | 0.557519804684 | gnomAD-4.0.0 | 6.84394E-07 | None | None | None | None | I | None | 0 | 2.23784E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 25192 |
Ig-134 |
82 | rs998111823 |
0.1981 | None | 1.0 | D | 0.673 | 0.632 | 0.617623114376 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 25192 |
Ig-134 |
82 | rs998111823 |
0.1981 | None | 1.0 | D | 0.673 | 0.632 | 0.617623114376 | gnomAD-4.0.0 | 2.47949E-06 | None | None | None | None | I | None | 5.3416E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 25589 |
Ig-135 |
76 | rs794729499 |
0.0724 | -0.316 | 0.09 | N | 0.335 | 0.083 | 0.154104182512 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 25589 |
Ig-135 |
76 | rs794729499 |
0.0724 | -0.316 | 0.09 | N | 0.335 | 0.083 | 0.154104182512 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 25589 |
Ig-135 |
76 | rs794729499 |
0.0724 | -0.316 | 0.09 | N | 0.335 | 0.083 | 0.154104182512 | gnomAD-4.0.0 | 3.71902E-06 | None | None | None | None | N | None | 5.34174E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47771E-07 | 0 | 1.60154E-05 |
| Q/H | 25878 |
Ig-136 |
81 | rs765550681 |
0.1882 | -0.561 | 0.939 | N | 0.424 | 0.325 | 0.448099371145 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| Q/H | 25878 |
Ig-136 |
81 | rs765550681 |
0.1882 | -0.561 | 0.939 | N | 0.424 | 0.325 | 0.448099371145 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Q/H | 25878 |
Ig-136 |
81 | rs765550681 |
0.1882 | -0.561 | 0.939 | N | 0.424 | 0.325 | 0.448099371145 | gnomAD-4.0.0 | 9.29748E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.27162E-05 | 0 | 0 |
| Q/K | 25878 |
Ig-136 |
81 | None | 0.0818 | None | 0.309 | N | 0.377 | 0.165 | 0.190952846119 | gnomAD-4.0.0 | 1.59208E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43324E-05 | 0 |
| Q/R | 25878 |
Ig-136 |
81 | rs886038876 |
0.0971 | None | 0.007 | N | 0.257 | 0.145 | 0.193865811164 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/P | 26671 |
Ig-138 |
78 | rs371983237 |
0.7271 | -0.375 | 0.667 | N | 0.46 | 0.378 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/I | 26960 |
Ig-139 |
81 | rs746547418 |
0.1021 | 0.084 | 0.317 | D | 0.555 | 0.22 | 0.321393169273 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/I | 26960 |
Ig-139 |
81 | rs746547418 |
0.1021 | 0.084 | 0.317 | D | 0.555 | 0.22 | 0.321393169273 | gnomAD-4.0.0 | 6.84264E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99525E-07 | 0 | 0 |
| T/R | 26960 |
Ig-139 |
81 | rs746547418 |
0.1172 | None | 0.062 | N | 0.544 | 0.167 | 0.317667799068 | gnomAD-4.0.0 | 6.84264E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15945E-05 | 0 |
| T/R | 27357 |
Ig-140 |
80 | rs754175266 |
0.1679 | 0.122 | 0.999 | N | 0.59 | 0.365 | 0.58308304948 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.56E-05 | 0 |
| T/R | 27357 |
Ig-140 |
80 | rs754175266 |
0.1679 | 0.122 | 0.999 | N | 0.59 | 0.365 | 0.58308304948 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 27357 |
Ig-140 |
80 | rs754175266 |
0.1679 | 0.122 | 0.999 | N | 0.59 | 0.365 | 0.58308304948 | gnomAD-4.0.0 | 1.54934E-05 | None | None | None | None | I | None | 0 | 1.66739E-05 | None | 0 | 0 | None | 0 | 1.64474E-04 | 1.86481E-05 | 0 | 1.60118E-05 |
| S/F | 27754 |
Ig-141 |
79 | rs1383167179 |
0.2116 | None | 0.99 | N | 0.662 | 0.399 | 0.677844904838 | gnomAD-4.0.0 | 1.59294E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88558E-05 | 0 | 0 | 0 | 0 |
| S/Y | 28043 |
Ig-142 |
81 | rs764567496 |
0.1623 | -0.46 | 0.295 | N | 0.59 | 0.335 | 0.646638679674 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| T/S | 28438 |
Ig-143 |
81 | None | 0.1067 | None | 0.999 | N | 0.607 | 0.23 | 0.317084106153 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| A/G | 28833 |
Ig-144 |
79 | None | 0.1385 | None | 0.166 | N | 0.353 | 0.165 | 0.284539287134 | gnomAD-4.0.0 | 6.84236E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15961E-05 | 0 |
| A/S | 28833 |
Ig-144 |
79 | rs368023553 |
0.079 | -0.082 | 0.005 | N | 0.167 | 0.084 | None | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | I | None | 6.20091E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/S | 28833 |
Ig-144 |
79 | rs368023553 |
0.079 | -0.082 | 0.005 | N | 0.167 | 0.084 | None | gnomAD-3.1.2 | 1.57712E-04 | None | None | None | None | I | None | 5.54778E-04 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/S | 28833 |
Ig-144 |
79 | rs368023553 |
0.079 | -0.082 | 0.005 | N | 0.167 | 0.084 | None | gnomAD-4.0.0 | 2.60281E-05 | None | None | None | None | I | None | 5.205E-04 | 1.66722E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.20246E-05 |
| A/T | 28833 |
Ig-144 |
79 | rs368023553 |
0.0613 | -0.143 | 0.002 | N | 0.165 | 0.093 | 0.152612264143 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| A/T | 28833 |
Ig-144 |
79 | rs368023553 |
0.0613 | -0.143 | 0.002 | N | 0.165 | 0.093 | 0.152612264143 | gnomAD-4.0.0 | 6.84245E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99499E-07 | 0 | 0 |
| A/V | 28833 |
Ig-144 |
79 | rs374108922 |
0.097 | 0.007 | 0.166 | N | 0.307 | 0.155 | None | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | I | None | 6.20091E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/V | 28833 |
Ig-144 |
79 | rs374108922 |
0.097 | 0.007 | 0.166 | N | 0.307 | 0.155 | None | gnomAD-3.1.2 | 1.57698E-04 | None | None | None | None | I | None | 5.54778E-04 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 28833 |
Ig-144 |
79 | rs374108922 |
0.097 | 0.007 | 0.166 | N | 0.307 | 0.155 | None | gnomAD-4.0.0 | 2.60276E-05 | None | None | None | None | I | None | 5.20486E-04 | 1.66683E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.20225E-05 |
| T/A | 29125 |
Ig-145 |
81 | rs1433625453 |
0.0811 | None | 0.999 | N | 0.572 | 0.416 | 0.368554958709 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 29125 |
Ig-145 |
81 | rs1433625453 |
0.0811 | None | 0.999 | N | 0.572 | 0.416 | 0.368554958709 | gnomAD-4.0.0 | 6.56996E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46994E-05 | 0 | 0 |
| T/I | 29125 |
Ig-145 |
81 | rs762768301 |
0.116 | None | 1.0 | N | 0.729 | 0.459 | 0.478828542108 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| T/I | 29125 |
Ig-145 |
81 | rs762768301 |
0.116 | None | 1.0 | N | 0.729 | 0.459 | 0.478828542108 | gnomAD-4.0.0 | 3.71881E-06 | None | None | None | None | N | None | 5.33832E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09791E-05 | 1.60118E-05 |
| T/K | 29125 |
Ig-145 |
81 | rs762768301 |
0.1838 | -0.332 | 1.0 | N | 0.747 | 0.476 | 0.424670345773 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11383E-04 | None | 0 | None | 0 | 0 | 0 |
| T/K | 29125 |
Ig-145 |
81 | rs762768301 |
0.1838 | -0.332 | 1.0 | N | 0.747 | 0.476 | 0.424670345773 | gnomAD-4.0.0 | 7.52791E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.7712E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 29521 |
Ig-146 |
78 | rs1436663696 |
0.0878 | 0.015 | 0.801 | N | 0.473 | 0.379 | 0.677831437009 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/L | 29521 |
Ig-146 |
78 | rs1436663696 |
0.0878 | 0.015 | 0.801 | N | 0.473 | 0.379 | 0.677831437009 | gnomAD-4.0.0 | 1.59116E-06 | None | None | None | None | I | None | 0 | 2.28634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 29920 |
Ig-147 |
79 | rs747181293 |
0.1279 | -0.286 | 0.052 | N | 0.349 | 0.106 | 0.186928172975 | gnomAD-2.1.1 | 8.06E-05 | None | None | None | None | I | None | 0 | 4.35111E-04 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 3.33E-04 |
| E/D | 29920 |
Ig-147 |
79 | rs747181293 |
0.1279 | -0.286 | 0.052 | N | 0.349 | 0.106 | 0.186928172975 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | I | None | 0 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 8.82E-05 | 0 | 4.77555E-04 |
| E/D | 29920 |
Ig-147 |
79 | rs747181293 |
0.1279 | -0.286 | 0.052 | N | 0.349 | 0.106 | 0.186928172975 | gnomAD-4.0.0 | 4.09236E-05 | None | None | None | None | I | None | 0 | 3.6674E-04 | None | 0 | 0 | None | 0 | 0 | 3.30783E-05 | 0 | 8.01E-05 |
| E/G | 29920 |
Ig-147 |
79 | None | 0.1404 | None | 0.117 | N | 0.477 | 0.334 | 0.358340041657 | gnomAD-4.0.0 | 1.59379E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43377E-05 | 0 |
| R/T | 30212 |
Ig-148 |
81 | rs762512777 |
0.5354 | -0.261 | 0.98 | N | 0.463 | 0.302 | 0.328222422547 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| R/T | 30212 |
Ig-148 |
81 | rs762512777 |
0.5354 | -0.261 | 0.98 | N | 0.463 | 0.302 | 0.328222422547 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| S/N | 31004 |
Ig-150 |
78 | rs762024916 |
0.1034 | 0.154 | 0.055 | D | 0.279 | 0.109 | 0.170165803431 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.63388E-04 | None | 0 | 0 | 0 |
| S/N | 31004 |
Ig-150 |
78 | rs762024916 |
0.1034 | 0.154 | 0.055 | D | 0.279 | 0.109 | 0.170165803431 | gnomAD-4.0.0 | 7.52596E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-04 | 1.65662E-05 |
| V/I | 31296 |
Ig-151 |
79 | rs794729534 |
0.0721 | -0.218 | 0.014 | N | 0.229 | 0.084 | 0.435808882951 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 1.29182E-04 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/I | 31296 |
Ig-151 |
79 | rs794729534 |
0.0721 | -0.218 | 0.014 | N | 0.229 | 0.084 | 0.435808882951 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 31296 |
Ig-151 |
79 | rs794729534 |
0.0721 | -0.218 | 0.014 | N | 0.229 | 0.084 | 0.435808882951 | gnomAD-4.0.0 | 1.15327E-05 | None | None | None | None | I | None | 1.35272E-04 | 1.69509E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 31696 |
Ig-152 |
76 | rs1205411867 |
0.0911 | -0.166 | 0.625 | D | 0.292 | 0.147 | 0.365120060079 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| T/A | 31696 |
Ig-152 |
76 | rs1205411867 |
0.0911 | -0.166 | 0.625 | D | 0.292 | 0.147 | 0.365120060079 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/A | 31696 |
Ig-152 |
76 | rs1205411867 |
0.0911 | -0.166 | 0.625 | D | 0.292 | 0.147 | 0.365120060079 | gnomAD-4.0.0 | 5.12847E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.58428E-06 | 0 | 0 |
| T/S | 31696 |
Ig-152 |
76 | None | 0.0968 | None | 0.891 | N | 0.236 | 0.184 | 0.30921473904 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 33278 |
Ig-157 |
76 | rs749065018 |
0.0987 | -0.513 | 0.336 | N | 0.52 | 0.144 | 0.299427821978 | gnomAD-2.1.1 | 4.19E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.69E-05 | None | 0 | None | 0 | 0 | 0 |
| T/R | 33278 |
Ig-157 |
76 | rs772862798 |
0.1261 | 0.018 | 0.997 | N | 0.653 | 0.482 | 0.789031109301 | gnomAD-2.1.1 | 8.41E-06 | None | None | None | None | I | None | 0 | 6.09E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/R | 33278 |
Ig-157 |
76 | rs772862798 |
0.1261 | 0.018 | 0.997 | N | 0.653 | 0.482 | 0.789031109301 | gnomAD-4.0.0 | 3.28861E-06 | None | None | None | None | I | None | 0 | 4.76894E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 33578 |
Ig-158 |
83 | rs749424660 |
0.953 | -0.53 | 0.999 | N | 0.719 | 0.612 | None | gnomAD-2.1.1 | 9.69E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.06E-05 | 0 |
| S/P | 33578 |
Ig-158 |
83 | rs749424660 |
0.953 | -0.53 | 0.999 | N | 0.719 | 0.612 | None | gnomAD-4.0.0 | 5.25819E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.31544E-06 | 0 | 0 |
| I/T | 33677 |
Ig-159 |
82 | rs1475771537 |
0.4661 | -0.1 | 0.949 | N | 0.475 | 0.207 | 0.608471955132 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| I/T | 33677 |
Ig-159 |
82 | rs1475771537 |
0.4661 | -0.1 | 0.949 | N | 0.475 | 0.207 | 0.608471955132 | gnomAD-4.0.0 | 3.18237E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71615E-06 | 0 | 0 |
| E/D | 34341 |
Ig-161 |
84 | rs1330415230 |
0.4419 | -0.33 | 0.046 | N | 0.261 | 0.111 | 0.326881540566 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| E/K | 35022 |
Ig-163 |
81 | rs727504977 |
0.4438 | 0.524 | 1.0 | D | 0.677 | 0.465 | 0.441636318388 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| E/K | 35022 |
Ig-163 |
81 | rs727504977 |
0.4438 | 0.524 | 1.0 | D | 0.677 | 0.465 | 0.441636318388 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| E/K | 35022 |
Ig-163 |
81 | rs727504977 |
0.4438 | 0.524 | 1.0 | D | 0.677 | 0.465 | 0.441636318388 | gnomAD-4.0.0 | 5.57677E-06 | None | None | None | None | N | None | 0 | 1.66672E-05 | None | 0 | 2.22747E-05 | None | 0 | 0 | 5.93281E-06 | 0 | 0 |
| K/Q | 35209 |
Ig-164 |
81 | rs56365812 |
0.1192 | 0.167 | 0.025 | N | 0.489 | 0.133 | 0.207176502487 | gnomAD-2.1.1 | 1.2E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.66889E-04 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 35209 |
Ig-164 |
81 | rs56365812 |
0.1192 | 0.167 | 0.025 | N | 0.489 | 0.133 | 0.207176502487 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 5.76923E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 35209 |
Ig-164 |
81 | rs56365812 |
0.1192 | 0.167 | 0.025 | N | 0.489 | 0.133 | 0.207176502487 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| K/Q | 35209 |
Ig-164 |
81 | rs56365812 |
0.1192 | 0.167 | 0.025 | N | 0.489 | 0.133 | 0.207176502487 | gnomAD-4.0.0 | 4.95663E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.33666E-04 | None | 0 | 0 | 0 | 0 | 3.20061E-05 |
| T/M | 35367 |
Ig-165 |
82 | rs377056111 |
0.1026 | -0.02 | 0.808 | N | 0.461 | 0.138 | None | gnomAD-2.1.1 | 4.28E-05 | None | None | None | None | I | None | 4.13E-05 | 2.83E-05 | None | 0 | 0 | None | 3.27E-05 | None | 1.59936E-04 | 3.12E-05 | 1.40252E-04 |
| T/M | 35367 |
Ig-165 |
82 | rs377056111 |
0.1026 | -0.02 | 0.808 | N | 0.461 | 0.138 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | I | None | 2.41E-05 | 6.54E-05 | 0 | 0 | 0 | None | 1.8875E-04 | 0 | 4.41E-05 | 0 | 0 |
| T/M | 35367 |
Ig-165 |
82 | rs377056111 |
0.1026 | -0.02 | 0.808 | N | 0.461 | 0.138 | None | gnomAD-4.0.0 | 1.10918E-04 | None | None | None | None | I | None | 5.34131E-05 | 1.66639E-05 | None | 0 | 2.22737E-05 | None | 3.28197E-04 | 0 | 1.24588E-04 | 1.09803E-05 | 6.40369E-05 |
| I/F | 35685 |
Ig-167 |
79 | None | 0.1754 | None | 0.171 | N | 0.364 | 0.078 | 0.416581338634 | gnomAD-4.0.0 | 1.59179E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43398E-05 | 0 |
| S/P | 35979 |
Ig-169 |
83 | None | 0.7331 | None | 0.966 | N | 0.476 | 0.456 | 0.37262878642 | gnomAD-4.0.0 | 1.59126E-06 | None | None | None | 0.09(OBSL1) 0.116(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85789E-06 | 0 | 0 |
| S/Y | 35979 |
Ig-169 |
83 | None | 0.2148 | None | 0.876 | D | 0.581 | 0.487 | 0.653374280352 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | 0.423(OBSL1) 0.494(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.