Structural position:

  • Domain Type: Ig
  • Aligned Position: 166
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand G

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
A/G 89 Ig-1 84 rs200165636 0.3265 -1.151 1.0 D 0.625 0.514 None gnomAD-2.1.1 1.37894E-04 None None None -0.196(TCAP) N None 8.01E-05 0 None 0 0 None 0 None 0 2.7875E-04 1.38389E-04
A/G 89 Ig-1 84 rs200165636 0.3265 -1.151 1.0 D 0.625 0.514 None gnomAD-3.1.2 1.24862E-04 None None None -0.196(TCAP) N None 1.44781E-04 6.54E-05 0 0 0 None 0 0 1.61665E-04 0 4.77555E-04
A/G 89 Ig-1 84 rs200165636 0.3265 -1.151 1.0 D 0.625 0.514 None gnomAD-4.0.0 2.16237E-04 None None None -0.196(TCAP) N None 1.06778E-04 1.6665E-05 None 0 0 None 0 0 2.82209E-04 0 1.12025E-04
A/T 89 Ig-1 84 rs1259283214 0.1491 None 1.0 N 0.752 0.43 0.486135451721 gnomAD-4.0.0 1.20039E-06 None None None -0.574(TCAP) N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
A/V 89 Ig-1 84 rs200165636 0.2035 -0.061 1.0 N 0.707 0.393 0.619501705969 gnomAD-2.1.1 7.95E-06 None None None -0.398(TCAP) N None 0 0 None 0 0 None 6.53E-05 None 0 0 0
A/V 89 Ig-1 84 rs200165636 0.2035 -0.061 1.0 N 0.707 0.393 0.619501705969 gnomAD-3.1.2 1.97E-05 None None None -0.398(TCAP) N None 2.41E-05 0 0 0 0 None 0 0 2.94E-05 0 0
A/V 89 Ig-1 84 rs200165636 0.2035 -0.061 1.0 N 0.707 0.393 0.619501705969 gnomAD-4.0.0 8.05467E-06 None None None -0.398(TCAP) N None 1.33472E-05 0 None 0 0 None 0 0 5.93232E-06 5.48968E-05 0
A/S 185 Ig-2 82 rs2094001955 0.1621 None 0.998 N 0.619 0.438 0.440915056915 gnomAD-3.1.2 6.57E-06 None None None -0.72(TCAP) I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/S 185 Ig-2 82 rs2094001955 0.1621 None 0.998 N 0.619 0.438 0.440915056915 gnomAD-4.0.0 6.57013E-06 None None None -0.72(TCAP) I None 2.41289E-05 0 None 0 0 None 0 0 0 0 0
A/V 185 Ig-2 82 None 0.3907 None 1.0 N 0.699 0.445 0.639084873237 gnomAD-4.0.0 1.59047E-06 None None None -1.265(TCAP) I None 0 0 None 0 0 None 0 0 2.85652E-06 0 0
V/F 1024 Ig-3 82 None 0.6497 None 0.999 D 0.778 0.388 0.8544907614 gnomAD-4.0.0 6.84403E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99408E-07 0 0
V/G 1024 Ig-3 82 rs879097187 0.8065 -1.16 0.999 N 0.83 0.674 None gnomAD-2.1.1 3.18E-05 None None None None I None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
V/G 1024 Ig-3 82 rs879097187 0.8065 -1.16 0.999 N 0.83 0.674 None gnomAD-4.0.0 1.3688E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.3151E-05
V/I 1024 Ig-3 82 rs368770038 0.1077 -0.29 0.768 N 0.217 0.26 None gnomAD-2.1.1 3.99E-05 None None None None I None 6.15E-05 0 None 0 0 None 3.27E-05 None 0 7.08E-05 0
V/I 1024 Ig-3 82 rs368770038 0.1077 -0.29 0.768 N 0.217 0.26 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 0 4.78011E-04
V/I 1024 Ig-3 82 rs368770038 0.1077 -0.29 0.768 N 0.217 0.26 None gnomAD-4.0.0 2.54131E-05 None None None None I None 0 0 None 0 0 None 0 0 3.30543E-05 1.09823E-05 1.60179E-05
T/I 1165 Ig-4 84 None 0.1028 None None N 0.253 0.096 0.144782658237 gnomAD-4.0.0 1.59087E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85701E-06 0 0
T/N 1165 Ig-4 84 rs762456074 0.1752 -0.58 0.484 N 0.51 0.105 0.21737058555 gnomAD-2.1.1 3.98E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.82E-06 0
A/T 1373 Ig-5 83 rs867802403 0.3348 None 1.0 N 0.769 0.457 None gnomAD-3.1.2 1.31E-05 None None None None I None 4.82E-05 0 0 0 0 None 0 0 0 0 0
A/T 1373 Ig-5 83 rs867802403 0.3348 None 1.0 N 0.769 0.457 None gnomAD-4.0.0 1.31411E-05 None None None None I None 4.82462E-05 0 None 0 0 None 0 0 0 0 0
A/V 1373 Ig-5 83 rs139294675 0.5362 0.059 1.0 N 0.697 0.431 None gnomAD-2.1.1 1.2E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.65E-05 0
A/V 1373 Ig-5 83 rs139294675 0.5362 0.059 1.0 N 0.697 0.431 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/V 1373 Ig-5 83 rs139294675 0.5362 0.059 1.0 N 0.697 0.431 None gnomAD-4.0.0 1.61102E-05 None None None None I None 0 0 None 0 0 None 0 0 2.11875E-05 0 1.60051E-05
D/G 1639 Ig-7 84 None 0.8162 None 1.0 D 0.765 0.726 0.480647642424 gnomAD-4.0.0 1.59118E-06 None None None None I None 0 2.28802E-05 None 0 0 None 0 0 0 0 0
D/V 1639 Ig-7 84 rs760219634 0.8918 0.428 1.0 N 0.871 0.714 0.575180444326 gnomAD-2.1.1 3.99E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
D/V 1639 Ig-7 84 rs760219634 0.8918 0.428 1.0 N 0.871 0.714 0.575180444326 gnomAD-4.0.0 1.59118E-06 None None None None I None 0 2.28802E-05 None 0 0 None 0 0 0 0 0
D/E 1786 Ig-8 84 None 0.7122 None 1.0 N 0.612 0.287 0.299770980665 gnomAD-4.0.0 6.86608E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99327E-07 0 0
D/N 1786 Ig-8 84 None 0.5495 None 1.0 D 0.735 0.443 0.364141725642 gnomAD-4.0.0 1.37311E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79864E-06 0 0
I/V 1921 Ig-9 81 rs879100565 0.0709 -0.953 None N 0.096 0.112 0.223146558224 gnomAD-2.1.1 7.08E-06 None None None None I None 4.01E-05 0 None 0 0 None 0 None 0 7.76E-06 0
I/V 1921 Ig-9 81 rs879100565 0.0709 -0.953 None N 0.096 0.112 0.223146558224 gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 1921 Ig-9 81 rs879100565 0.0709 -0.953 None N 0.096 0.112 0.223146558224 gnomAD-4.0.0 1.54892E-05 None None None None I None 2.66944E-05 0 None 0 0 None 0 0 1.86442E-05 0 1.60041E-05
T/A 2160 Ig-10 83 rs397517693 0.1268 -0.888 0.061 N 0.149 0.111 None gnomAD-2.1.1 3.54E-05 None None None None I None 0 1.12975E-04 None 0 0 None 0 None 0 4.66E-05 0
T/A 2160 Ig-10 83 rs397517693 0.1268 -0.888 0.061 N 0.149 0.111 None gnomAD-3.1.2 2.63E-05 None None None None I None 2.42E-05 6.55E-05 0 0 0 None 0 0 2.94E-05 0 0
T/A 2160 Ig-10 83 rs397517693 0.1268 -0.888 0.061 N 0.149 0.111 None 1000 genomes 1.99681E-04 None None None None I None 0 1.4E-03 None None 0 0 None None None 0 None
T/A 2160 Ig-10 83 rs397517693 0.1268 -0.888 0.061 N 0.149 0.111 None gnomAD-4.0.0 4.02744E-05 None None None None I None 2.66773E-05 8.33472E-05 None 0 0 None 1.56299E-05 0 4.66108E-05 0 3.1999E-05
T/I 2160 Ig-10 83 rs750401975 0.548 0.01 0.988 N 0.533 0.434 0.442567846599 gnomAD-2.1.1 3.98E-06 None None None None I None 6.15E-05 0 None 0 0 None 0 None 0 0 0
T/I 2160 Ig-10 83 rs750401975 0.548 0.01 0.988 N 0.533 0.434 0.442567846599 gnomAD-4.0.0 2.05229E-06 None None None None I None 2.98757E-05 0 None 0 0 None 0 0 1.79859E-06 0 0
T/N 2160 Ig-10 83 None 0.3585 None 0.92 N 0.499 0.373 0.414539908741 gnomAD-4.0.0 6.84097E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99295E-07 0 0
V/D 2254 Ig-11 81 None 0.3347 None 0.667 N 0.662 0.286 0.824782275277 gnomAD-4.0.0 1.59473E-06 None None None None N None 0 0 None 0 0 None 1.89451E-05 0 0 0 0
V/I 2254 Ig-11 81 rs1401971730 0.0612 -0.178 None N 0.119 0.137 0.110078149338 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/I 2254 Ig-11 81 rs1401971730 0.0612 -0.178 None N 0.119 0.137 0.110078149338 gnomAD-4.0.0 1.3685E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.31889E-05 0
K/Q 2343 Ig-12 77 None 0.1114 None 0.998 N 0.481 0.321 0.267755039894 gnomAD-4.0.0 6.84092E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99313E-07 0 0
V/A 2522 Ig-14 78 rs1163155086 0.1101 None 0.489 N 0.545 0.191 0.258779203287 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 6.07533E-05 0
L/F 2871 Ig-18 77 None 0.2445 None 0.982 N 0.611 0.295 0.535102873643 gnomAD-4.0.0 1.59046E-06 None None None None N None 0 0 None 0 0 None 1.88168E-05 0 0 0 0
L/M 2871 Ig-18 77 None 0.1224 None 0.982 N 0.622 0.388 0.16115917748 gnomAD-4.0.0 1.59046E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02151E-05
A/D 2962 Ig-19 81 rs1234280033 0.9868 -1.609 1.0 D 0.866 0.807 0.858568201941 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
A/D 2962 Ig-19 81 rs1234280033 0.9868 -1.609 1.0 D 0.866 0.807 0.858568201941 gnomAD-4.0.0 1.59199E-06 None None None None N None 0 2.28718E-05 None 0 0 None 0 0 0 0 0
A/P 2962 Ig-19 81 rs765523736 0.9978 -0.626 1.0 D 0.844 0.776 None gnomAD-2.1.1 3.88594E-04 None None None None N None 0 2.93E-05 None 0 5.59E-05 None 6.55E-05 None 3.4763E-03 1.4817E-04 5.07442E-04
A/P 2962 Ig-19 81 rs765523736 0.9978 -0.626 1.0 D 0.844 0.776 None gnomAD-4.0.0 8.22534E-06 None None None None N None 0 6.75919E-05 None 0 1.01107E-04 None 5.75727E-05 0 8.99879E-07 0 1.66168E-05
A/T 2962 Ig-19 81 rs765523736 0.5928 -1.36 1.0 D 0.666 0.604 None gnomAD-4.0.0 4.7976E-06 None None None None N None 0 0 None 0 0 None 0 0 6.29892E-06 0 0
A/V 2962 Ig-19 81 None 0.851 None 1.0 D 0.59 0.615 0.709893862867 gnomAD-4.0.0 1.59199E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02517E-05
A/S 3045 Ig-20 77 None 0.1232 None 0.284 N 0.324 0.127 0.224531998449 gnomAD-4.0.0 6.84156E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99308E-07 0 0
A/T 3045 Ig-20 77 rs755527049 0.2452 -0.776 0.865 N 0.571 0.275 0.361558571881 gnomAD-2.1.1 7.98E-06 None None None None N None 6.18E-05 0 None 0 0 None 0 None 0 8.82E-06 0
A/T 3045 Ig-20 77 rs755527049 0.2452 -0.776 0.865 N 0.571 0.275 0.361558571881 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 3045 Ig-20 77 rs755527049 0.2452 -0.776 0.865 N 0.571 0.275 0.361558571881 gnomAD-4.0.0 4.95734E-06 None None None None N None 2.66951E-05 0 None 0 0 None 0 0 4.23737E-06 0 1.60072E-05
N/K 3225 Ig-22 79 rs1244268787 0.9155 0.334 0.996 N 0.446 0.167 0.141422826196 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 9.93E-05 0 None 0 None 0 0 0
N/K 3225 Ig-22 79 rs1244268787 0.9155 0.334 0.996 N 0.446 0.167 0.141422826196 gnomAD-4.0.0 6.84191E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9947E-07 0 0
N/S 3225 Ig-22 79 rs202011992 0.3885 -0.161 0.905 N 0.241 0.199 None gnomAD-2.1.1 4.25E-05 None None None None N None 4.01E-05 0 None 0 0 None 0 None 0 8.53E-05 0
N/S 3225 Ig-22 79 rs202011992 0.3885 -0.161 0.905 N 0.241 0.199 None gnomAD-3.1.2 5.91E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.17606E-04 0 0
N/S 3225 Ig-22 79 rs202011992 0.3885 -0.161 0.905 N 0.241 0.199 None gnomAD-4.0.0 9.91407E-05 None None None None N None 2.66951E-05 0 None 0 0 None 0 0 1.26284E-04 0 1.44055E-04
A/T 3320 Ig-23 82 rs144100066 0.1467 -1.031 0.928 N 0.641 0.396 None gnomAD-2.1.1 2.13E-05 None None None None I None 4E-05 2.82E-05 None 0 0 None 0 None 0 2.34E-05 1.38581E-04
A/T 3320 Ig-23 82 rs144100066 0.1467 -1.031 0.928 N 0.641 0.396 None gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 3320 Ig-23 82 rs144100066 0.1467 -1.031 0.928 N 0.641 0.396 None gnomAD-4.0.0 5.57619E-06 None None None None I None 4.00395E-05 1.66644E-05 None 0 0 None 0 0 2.54233E-06 0 3.20102E-05
A/V 3320 Ig-23 82 None 0.159 None 0.039 N 0.341 0.155 0.376039117802 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
V/E 3425 Ig-24 81 None 0.4945 None 0.998 N 0.71 0.561 0.85112795881 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 1.01626E-03 None 0 0 None 0 0 0 0 0
V/I 3425 Ig-24 81 rs879184037 0.1069 None 0.987 N 0.521 0.374 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 3425 Ig-24 81 rs879184037 0.1069 None 0.987 N 0.521 0.374 None gnomAD-4.0.0 3.84228E-06 None None None None I None 0 0 None 0 0 None 0 0 7.17638E-06 0 0
A/G 3548 Ig-25 84 rs1386570246 0.2744 -1.202 None None None 0.332 None gnomAD-2.1.1 4.16E-06 None None None None I None 0 3.01E-05 None 0 0 None 0 None 0 0 0
A/G 3548 Ig-25 84 rs1386570246 0.2744 -1.202 None None None 0.332 None gnomAD-4.0.0 1.63618E-06 None None None None I None 0 2.35217E-05 None 0 0 None 0 0 0 0 0
A/T 3548 Ig-25 84 rs1186138216 0.1238 -0.884 None None None 0.124 None gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
A/T 3548 Ig-25 84 rs1186138216 0.1238 -0.884 None None None 0.124 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 3548 Ig-25 84 rs1186138216 0.1238 -0.884 None None None 0.124 None gnomAD-4.0.0 6.57073E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47007E-05 0 0
R/K 3741 Ig-26 82 rs773277489 0.0696 -0.432 None None None 0.117 None gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
R/K 3741 Ig-26 82 rs773277489 0.0696 -0.432 None None None 0.117 None gnomAD-4.0.0 2.05456E-06 None None None None I None 0 0 None 0 0 None 0 0 1.80068E-06 0 1.65772E-05
T/I 3901 Ig-27 82 rs1388046179 0.1901 0.102 None N 0.328 0.216 None gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
T/I 3901 Ig-27 82 rs1388046179 0.1901 0.102 None N 0.328 0.216 None gnomAD-4.0.0 1.36839E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79889E-06 0 0
S/Y 4020 Ig-28 83 rs1273620132 0.2548 -0.361 0.56 D 0.598 0.292 None gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
S/Y 4020 Ig-28 83 rs1273620132 0.2548 -0.361 0.56 D 0.598 0.292 None gnomAD-4.0.0 2.73764E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69831E-06 0 1.65667E-05
T/I 4686 Ig-29 81 rs1436112479 0.1684 None None N 0.303 0.131 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/I 4686 Ig-29 81 rs1436112479 0.1684 None None N 0.303 0.131 None gnomAD-4.0.0 1.97805E-06 None None None None I None 0 0 None 0 0 None 0 0 2.64547E-06 0 0
T/K 4686 Ig-29 81 None 0.1979 None None N 0.223 0.143 None gnomAD-4.0.0 2.93143E-06 None None None None I None 0 0 None 0 0 None 0 0 3.75235E-06 0 0
V/I 4781 Ig-30 82 rs2081852478 0.0973 None 0.549 N 0.486 0.204 0.594113984522 gnomAD-4.0.0 1.59172E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85925E-06 0 0
S/G 4969 Ig-32 82 None 0.1149 None 0.98 D 0.551 0.307 0.296679040009 gnomAD-4.0.0 1.63519E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.51616E-05 0
S/N 4969 Ig-32 82 rs762810073 0.1582 -0.381 0.99 N 0.591 0.302 0.280987212366 gnomAD-2.1.1 8.54E-06 None None None None N None 0 0 None 0 5.84E-05 None 0 None 0 9.28E-06 0
S/N 4969 Ig-32 82 rs762810073 0.1582 -0.381 0.99 N 0.591 0.302 0.280987212366 gnomAD-4.0.0 1.63777E-06 None None None None N None 0 0 None 0 0 None 0 0 2.91795E-06 0 0
C/Y 5156 Ig-34 82 None 0.3174 None 0.996 D 0.663 0.402 0.770558164856 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 6.07533E-05 0
S/G 5342 Ig-36 82 None 0.1466 None 0.906 N 0.361 0.294 0.28492961333 gnomAD-4.0.0 6.86201E-07 None None None None N None 0 0 None 0 0 None 0 0 9.01556E-07 0 0
K/E 5438 Ig-37 82 None 0.1545 None 0.961 N 0.541 0.314 0.423480098753 gnomAD-4.0.0 1.59333E-06 None None None None I None 0 0 None 0 2.78009E-05 None 0 0 0 0 0
K/R 5438 Ig-37 82 rs190636272 0.0807 -0.09 0.98 N 0.554 0.237 None gnomAD-2.1.1 5.7671E-04 None None None None I None 8.27E-05 5.67E-05 None 0 0 None 0 None 3.20847E-04 1.13781E-03 5.6338E-04
K/R 5438 Ig-37 82 rs190636272 0.0807 -0.09 0.98 N 0.554 0.237 None gnomAD-3.1.2 5.97984E-04 None None None None I None 7.24E-05 6.55E-05 0 0 0 None 9.42E-05 0 1.22005E-03 4.14079E-04 4.78011E-04
K/R 5438 Ig-37 82 rs190636272 0.0807 -0.09 0.98 N 0.554 0.237 None 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 1E-03 None None None 0 None
K/R 5438 Ig-37 82 rs190636272 0.0807 -0.09 0.98 N 0.554 0.237 None gnomAD-4.0.0 8.02846E-04 None None None None I None 1.19949E-04 6.66933E-05 None 0 0 None 2.18791E-04 0 1.04133E-03 4.3958E-05 5.76461E-04
D/E 5625 Ig-39 83 rs794729612 0.2914 None 0.999 N 0.541 0.226 0.441118900842 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
D/V 5625 Ig-39 83 rs746590786 0.3087 0.351 0.884 N 0.57 0.328 None gnomAD-2.1.1 1.43E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.14E-05 0
D/V 5625 Ig-39 83 rs746590786 0.3087 0.351 0.884 N 0.57 0.328 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/V 5625 Ig-39 83 rs746590786 0.3087 0.351 0.884 N 0.57 0.328 None gnomAD-4.0.0 2.85399E-05 None None None None N None 0 0 None 0 0 None 0 0 3.90337E-05 0 0
S/N 5718 Ig-40 82 None 0.1395 None 0.351 N 0.407 0.153 0.165133752707 gnomAD-4.0.0 6.8467E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00045E-07 0 0
Q/K 5811 Ig-41 82 None 0.1684 None 0.959 N 0.379 0.262 0.299086750705 gnomAD-4.0.0 2.05267E-06 None None None None I None 2.98846E-05 0 None 0 0 None 1.87336E-05 0 8.99486E-07 0 0
Q/P 5811 Ig-41 82 rs776791851 0.763 -0.039 0.998 N 0.531 0.521 0.421550847248 gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
Q/P 5811 Ig-41 82 rs776791851 0.763 -0.039 0.998 N 0.531 0.521 0.421550847248 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
Q/P 5811 Ig-41 82 rs776791851 0.763 -0.039 0.998 N 0.531 0.521 0.421550847248 gnomAD-4.0.0 6.57082E-06 None None None None I None 2.41161E-05 0 None 0 0 None 0 0 0 0 0
S/G 5904 Ig-42 82 rs749341609 0.1108 -0.887 0.135 N 0.229 0.183 0.198526703765 gnomAD-2.1.1 1.44E-05 None None None None I None 1.2409E-04 0 None 0 0 None 0 None 0 0 1.41403E-04
S/G 5904 Ig-42 82 rs749341609 0.1108 -0.887 0.135 N 0.229 0.183 0.198526703765 gnomAD-3.1.2 3.29E-05 None None None None I None 1.20785E-04 0 0 0 0 None 0 0 0 0 0
S/G 5904 Ig-42 82 rs749341609 0.1108 -0.887 0.135 N 0.229 0.183 0.198526703765 gnomAD-4.0.0 4.9688E-06 None None None None I None 9.36605E-05 0 None 0 0 None 0 0 0 0 1.60442E-05
S/N 5904 Ig-42 82 rs1234235732 0.1477 None 0.4 D 0.347 0.196 0.199424873507 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
S/N 5904 Ig-42 82 rs1234235732 0.1477 None 0.4 D 0.347 0.196 0.199424873507 gnomAD-4.0.0 6.57687E-06 None None None None I None 0 6.55136E-05 None 0 0 None 0 0 0 0 0
S/R 5904 Ig-42 82 None 0.6378 None 0.997 N 0.648 0.391 0.418718287753 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/T 5904 Ig-42 82 None 0.1259 None 0.98 N 0.559 0.246 0.268211541103 gnomAD-4.0.0 1.60137E-06 None None None None I None 5.69801E-05 0 None 0 0 None 0 0 0 0 0
N/D 6000 Ig-43 82 None 0.1227 None None N 0.091 0.146 0.173771789658 gnomAD-4.0.0 1.59313E-06 None None None None N None 0 0 None 0 0 None 1.88253E-05 0 0 0 0
A/V 6187 Ig-45 83 rs758380777 0.1249 -0.092 0.729 N 0.499 0.281 None gnomAD-2.1.1 2.82E-05 None None None None N None 6.47E-05 0 None 0 5.57E-05 None 1.30719E-04 None 0 8.92E-06 0
A/V 6187 Ig-45 83 rs758380777 0.1249 -0.092 0.729 N 0.499 0.281 None gnomAD-3.1.2 1.97E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 2.07641E-04 0
A/V 6187 Ig-45 83 rs758380777 0.1249 -0.092 0.729 N 0.499 0.281 None gnomAD-4.0.0 7.43705E-06 None None None None N None 5.34117E-05 0 None 0 0 None 0 0 2.54304E-06 5.4904E-05 0
C/S 6280 Ig-46 82 rs768034029 0.1779 -0.282 0.98 N 0.651 0.494 0.671445999895 gnomAD-2.1.1 4.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.96E-06 0
C/S 6280 Ig-46 82 rs768034029 0.1779 -0.282 0.98 N 0.651 0.494 0.671445999895 gnomAD-4.0.0 1.59696E-06 None None None None I None 0 0 None 0 0 None 0 0 2.87082E-06 0 0
C/Y 6280 Ig-46 82 rs768034029 0.3916 None 0.999 N 0.787 0.333 0.772397396667 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
C/Y 6280 Ig-46 82 rs768034029 0.3916 None 0.999 N 0.787 0.333 0.772397396667 gnomAD-4.0.0 6.57298E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47029E-05 0 0
E/G 6373 Ig-47 82 rs367868361 0.3563 -1.371 0.959 N 0.503 0.264 None gnomAD-2.1.1 2.16E-05 None None None None I None 4.14E-05 0 None 0 0 None 0 None 0 3.94E-05 0
E/G 6373 Ig-47 82 rs367868361 0.3563 -1.371 0.959 N 0.503 0.264 None gnomAD-3.1.2 2.63E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 4.41E-05 0 0
E/G 6373 Ig-47 82 rs367868361 0.3563 -1.371 0.959 N 0.503 0.264 None gnomAD-4.0.0 7.39472E-05 None None None None I None 1.33629E-05 0 None 0 0 None 0 0 9.8529E-05 0 3.21151E-05
E/K 6373 Ig-47 82 rs1310419887 0.4098 -0.361 0.979 N 0.395 0.33 0.339555952218 gnomAD-2.1.1 4.07E-06 None None None None I None 0 0 None 0 5.59E-05 None 0 None 0 0 0
S/G 6466 Ig-48 82 None 0.1528 None 0.959 N 0.477 0.37 0.254244900254 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
D/V 6562 Ig-49 82 None 0.1318 None 0.012 N 0.454 0.129 0.376570364461 gnomAD-4.0.0 4.87976E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.45395E-05 0
D/G 6655 Ig-50 82 rs772947420 0.2094 -0.943 0.933 D 0.507 0.322 None gnomAD-2.1.1 2.27E-05 None None None None I None 2.09153E-04 3.11E-05 None 0 0 None 0 None 0 0 0
D/G 6655 Ig-50 82 rs772947420 0.2094 -0.943 0.933 D 0.507 0.322 None gnomAD-3.1.2 3.3E-05 None None None None I None 1.21236E-04 0 0 0 0 None 0 0 0 0 0
D/G 6655 Ig-50 82 rs772947420 0.2094 -0.943 0.933 D 0.507 0.322 None gnomAD-4.0.0 1.32081E-05 None None None None I None 1.55333E-04 1.80187E-05 None 0 0 None 0 0 0 0 0
D/N 6655 Ig-50 82 rs397517493 0.1136 -0.636 1.0 N 0.565 0.376 0.378847511475 gnomAD-2.1.1 3.77E-05 None None None None I None 0 3.1E-05 None 0 3.13414E-04 None 3.73E-05 None 0 1.63E-05 0
D/N 6655 Ig-50 82 rs397517493 0.1136 -0.636 1.0 N 0.565 0.376 0.378847511475 gnomAD-3.1.2 2.63E-05 None None None None I None 0 0 0 0 1.93424E-04 None 0 0 4.41E-05 0 0
D/N 6655 Ig-50 82 rs397517493 0.1136 -0.636 1.0 N 0.565 0.376 0.378847511475 gnomAD-4.0.0 6.03057E-05 None None None None I None 0 1.76579E-05 None 0 1.34342E-04 None 0 0 7.35503E-05 1.14924E-05 3.24897E-05
T/R 6749 Ig-51 83 rs2079475430 0.1989 None 0.029 N 0.529 0.181 0.31411915649 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 3.16456E-03 0 0 0
T/R 6749 Ig-51 83 rs2079475430 0.1989 None 0.029 N 0.529 0.181 0.31411915649 gnomAD-4.0.0 1.88295E-06 None None None None I None 0 0 None 0 0 None 0 1.67224E-04 0 0 3.25024E-05
D/G 6842 Ig-52 82 rs747784796 0.324 -1.126 0.722 N 0.63 0.354 0.301122078929 gnomAD-2.1.1 2.04E-05 None None None None I None 0 0 None 0 0 None 1.34707E-04 None 0 9.01E-06 0
D/G 6842 Ig-52 82 rs747784796 0.324 -1.126 0.722 N 0.63 0.354 0.301122078929 gnomAD-4.0.0 1.37473E-05 None None None None I None 0 0 None 0 0 None 0 0 1.26417E-05 5.85658E-05 1.66439E-05
D/V 6842 Ig-52 82 rs747784796 0.516 0.232 0.901 N 0.793 0.346 0.620998120304 gnomAD-2.1.1 8.16E-06 None None None None I None 0 0 None 0 0 None 6.74E-05 None 0 0 0
D/V 6842 Ig-52 82 rs747784796 0.516 0.232 0.901 N 0.793 0.346 0.620998120304 gnomAD-4.0.0 2.0621E-06 None None None None I None 0 0 None 0 0 None 0 0 0 3.51395E-05 0
R/K 6936 Ig-53 83 rs1206230320 0.1158 -0.684 None N None 0.191 None gnomAD-2.1.1 4.35E-06 None None None None I None 0 0 None 0 0 None 3.71E-05 None 0 0 0
R/K 6936 Ig-53 83 rs1206230320 0.1158 -0.684 None N None 0.191 None gnomAD-4.0.0 2.77145E-06 None None None None I None 0 0 None 0 0 None 0 0 9.07604E-07 3.63064E-05 0
R/W 6936 Ig-53 83 rs762861187 0.2101 -0.149 None N None 0.452 None gnomAD-2.1.1 1.14E-05 None None None None I None 1.2727E-04 0 None 0 0 None 0 None 0 0 0
R/W 6936 Ig-53 83 rs762861187 0.2101 -0.149 None N None 0.452 None gnomAD-3.1.2 2.63E-05 None None None None I None 9.65E-05 0 0 0 0 None 0 0 0 0 0
R/W 6936 Ig-53 83 rs762861187 0.2101 -0.149 None N None 0.452 None gnomAD-4.0.0 6.54822E-06 None None None None I None 8.48205E-05 0 None 0 0 None 0 0 0 0 0
S/N 7029 Ig-54 82 rs1371527659 0.1978 -0.327 0.961 N 0.557 0.239 0.226586394389 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.66168E-04
S/N 7029 Ig-54 82 rs1371527659 0.1978 -0.327 0.961 N 0.557 0.239 0.226586394389 gnomAD-4.0.0 1.59236E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02627E-05
D/N 7125 Ig-55 82 None 0.1497 None 0.999 N 0.596 0.371 0.423954403188 gnomAD-4.0.0 1.59427E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86475E-06 0 0
A/T 7218 Ig-56 82 rs1286778967 0.0762 -0.753 None D 0.091 0.166 0.0666544352282 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
A/T 7218 Ig-56 82 rs1286778967 0.0762 -0.753 None D 0.091 0.166 0.0666544352282 gnomAD-4.0.0 4.77948E-06 None None None None N None 0 0 None 0 0 None 0 0 8.58276E-06 0 0
A/V 7218 Ig-56 82 rs763125654 0.0993 -0.014 None N 0.141 0.151 0.324436698001 gnomAD-2.1.1 6.06E-05 None None None None N None 0 4.36834E-04 None 0 0 None 0 None 0 0 0
A/V 7218 Ig-56 82 rs763125654 0.0993 -0.014 None N 0.141 0.151 0.324436698001 gnomAD-4.0.0 2.86757E-05 None None None None N None 0 4.12163E-04 None 0 0 None 0 0 0 0 0
D/E 7311 Ig-57 82 rs746715340 0.4745 -0.436 0.948 N 0.472 0.364 0.306053231325 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
D/E 7311 Ig-57 82 rs746715340 0.4745 -0.436 0.948 N 0.472 0.364 0.306053231325 gnomAD-4.0.0 1.59181E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85927E-06 0 0
D/N 7311 Ig-57 82 rs1205648849 0.2689 -0.783 0.989 N 0.597 0.402 0.366277470483 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.66445E-04
A/S 7404 Ig-58 82 None 0.1065 None 0.136 N 0.335 0.189 0.238705975628 gnomAD-4.0.0 6.84774E-07 None None None None I None 0 0 None 0 2.52423E-05 None 0 0 0 0 0
A/T 7404 Ig-58 82 None 0.0878 None 0.669 N 0.42 0.249 0.337135696972 gnomAD-4.0.0 6.84774E-07 None None None None I None 0 2.24004E-05 None 0 0 None 0 0 0 0 0
A/S 7500 Ig-59 82 rs1204148672 0.1122 None 0.583 N 0.428 0.28 0.281381271821 gnomAD-4.0.0 6.88547E-07 None None None None I None 0 2.2718E-05 None 0 0 None 0 0 0 0 0
A/V 7500 Ig-59 82 rs1560689342 0.1621 None 0.999 N 0.539 0.341 0.591496729656 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/V 7500 Ig-59 82 rs1560689342 0.1621 None 0.999 N 0.539 0.341 0.591496729656 gnomAD-4.0.0 6.57177E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47011E-05 0 0
D/E 7596 Ig-60 82 None 0.3602 None 0.01 N 0.296 0.102 0.190952846119 gnomAD-4.0.0 1.59471E-06 None None None None I None 0 0 None 0 2.77331E-05 None 0 0 0 0 0
D/H 7596 Ig-60 82 rs72648970 0.6461 0.105 0.999 N 0.679 0.421 None gnomAD-2.1.1 2.80405E-02 None None None None I None 5.12863E-03 1.17927E-02 None 2.24522E-02 1.53689E-04 None 4.63683E-02 None 2.72654E-02 3.72437E-02 3.07649E-02
D/H 7596 Ig-60 82 rs72648970 0.6461 0.105 0.999 N 0.679 0.421 None gnomAD-3.1.2 2.43494E-02 None None None None I None 5.3543E-03 1.8926E-02 4.82456E-02 2.10496E-02 1.92678E-04 None 2.6078E-02 1.58228E-02 3.70419E-02 4.64345E-02 2.43786E-02
D/H 7596 Ig-60 82 rs72648970 0.6461 0.105 0.999 N 0.679 0.421 None 1000 genomes 2.01677E-02 None None None None I None 8E-04 2.16E-02 None None 0 3.68E-02 None None None 4.91E-02 None
D/H 7596 Ig-60 82 rs72648970 0.6461 0.105 0.999 N 0.679 0.421 None gnomAD-4.0.0 3.37577E-02 None None None None I None 4.93254E-03 1.44311E-02 None 2.26487E-02 8.91623E-05 None 2.82618E-02 3.68595E-02 3.75621E-02 4.69607E-02 3.04608E-02
D/N 7596 Ig-60 82 None 0.201 None 0.977 D 0.616 0.337 0.322510055762 gnomAD-4.0.0 6.84868E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.16322E-05 0
D/Y 7596 Ig-60 82 rs72648970 0.4794 0.599 1.0 D 0.818 0.448 0.776745378001 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.93E-06 0
A/S 7690 Ig-61 83 rs763029699 0.1051 -1.089 0.039 D 0.477 0.151 0.315903272564 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.96E-06 0
A/S 7690 Ig-61 83 rs763029699 0.1051 -1.089 0.039 D 0.477 0.151 0.315903272564 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/S 7690 Ig-61 83 rs763029699 0.1051 -1.089 0.039 D 0.477 0.151 0.315903272564 gnomAD-4.0.0 5.00611E-06 None None None None N None 0 0 None 0 0 None 0 0 6.85181E-06 0 0
A/T 7690 Ig-61 83 rs763029699 0.0932 -1.005 0.005 N 0.361 0.147 0.352476196916 gnomAD-2.1.1 3.23E-05 None None None None N None 0 8.56E-05 None 0 0 None 0 None 0 4.72E-05 0
A/T 7690 Ig-61 83 rs763029699 0.0932 -1.005 0.005 N 0.361 0.147 0.352476196916 gnomAD-3.1.2 1.31E-05 None None None None N None 0 6.55E-05 0 0 0 None 0 0 1.47E-05 0 0
A/T 7690 Ig-61 83 rs763029699 0.0932 -1.005 0.005 N 0.361 0.147 0.352476196916 gnomAD-4.0.0 1.93972E-05 None None None None N None 0 6.70691E-05 None 3.06477E-04 0 None 0 0 1.28472E-05 2.22445E-05 1.61933E-05
A/V 7690 Ig-61 83 rs773024652 0.1295 -0.136 0.003 N 0.147 0.232 0.40146981186 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
D/G 7783 Ig-62 82 rs2078167222 0.407 None 0.862 N 0.527 0.432 0.329282125956 gnomAD-3.1.2 6.57E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
D/G 7783 Ig-62 82 rs2078167222 0.407 None 0.862 N 0.527 0.432 0.329282125956 gnomAD-4.0.0 6.57065E-06 None None None None I None 0 6.54793E-05 None 0 0 None 0 0 0 0 0
D/H 7783 Ig-62 82 None 0.7186 None 0.998 N 0.545 0.454 0.381071309025 gnomAD-4.0.0 1.59308E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86116E-06 0 0
D/N 8066 Ig-65 82 rs755202091 0.1287 -0.588 0.426 N 0.442 0.267 None gnomAD-2.1.1 1.21E-05 None None None None I None 6.48E-05 2.9E-05 None 0 0 None 0 None 0 8.97E-06 0
D/N 8066 Ig-65 82 rs755202091 0.1287 -0.588 0.426 N 0.442 0.267 None gnomAD-3.1.2 3.29E-05 None None None None I None 1.20691E-04 0 0 0 0 None 0 0 0 0 0
D/N 8066 Ig-65 82 rs755202091 0.1287 -0.588 0.426 N 0.442 0.267 None gnomAD-4.0.0 1.73544E-05 None None None None I None 6.67628E-05 5.00117E-05 None 0 0 None 0 1.64582E-04 1.6107E-05 0 0
A/S 8159 Ig-66 82 None 0.0932 None 0.454 N 0.499 0.298 0.276482976112 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/A 8252 Ig-67 82 rs762054067 0.5108 None 0.543 N 0.483 0.333 0.453119318887 gnomAD-4.0.0 6.84275E-07 None None None None N None 2.98918E-05 0 None 0 0 None 0 0 0 0 0
D/E 8252 Ig-67 82 rs764248656 0.62 0.095 0.543 N 0.243 0.11 0.225215365344 gnomAD-2.1.1 1.50167E-04 None None None None N None 0 0 None 0 2.04939E-03 None 0 None 0 0 2.81611E-04
D/E 8252 Ig-67 82 rs764248656 0.62 0.095 0.543 N 0.243 0.11 0.225215365344 gnomAD-3.1.2 7.23E-05 None None None None N None 0 0 0 0 2.12273E-03 None 0 0 0 0 0
D/E 8252 Ig-67 82 rs764248656 0.62 0.095 0.543 N 0.243 0.11 0.225215365344 gnomAD-4.0.0 4.21391E-05 None None None None N None 0 0 None 0 1.24833E-03 None 0 0 0 2.19616E-05 1.60046E-04
D/G 8252 Ig-67 82 rs762054067 0.4997 -0.513 0.989 N 0.587 0.506 0.433936292671 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
D/G 8252 Ig-67 82 rs762054067 0.4997 -0.513 0.989 N 0.587 0.506 0.433936292671 gnomAD-4.0.0 6.84275E-07 None None None None N None 0 0 None 0 2.51953E-05 None 0 0 0 0 0
D/H 8252 Ig-67 82 rs1173109154 0.8494 0.332 1.0 D 0.699 0.463 0.518312163451 gnomAD-2.1.1 7.15E-06 None None None None N None 0 0 None 0 1.0247E-04 None 0 None 0 0 0
D/H 8252 Ig-67 82 rs1173109154 0.8494 0.332 1.0 D 0.699 0.463 0.518312163451 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92753E-04 None 0 0 0 0 0
D/H 8252 Ig-67 82 rs1173109154 0.8494 0.332 1.0 D 0.699 0.463 0.518312163451 gnomAD-4.0.0 1.85926E-06 None None None None N None 0 0 None 0 6.68479E-05 None 0 0 0 0 0
D/V 8252 Ig-67 82 None 0.7803 None 0.997 N 0.749 0.483 0.687860213003 gnomAD-4.0.0 6.84275E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99549E-07 0 0
V/A 8345 Ig-68 82 None 0.1059 None None N 0.084 0.139 0.319114376414 gnomAD-4.0.0 6.37397E-06 None None None None I None 0 2.28728E-05 None 0 0 None 0 0 8.59303E-06 0 0
A/V 8441 Ig-69 82 rs2077677779 0.1729 None 0.542 N 0.366 0.282 0.428169733428 gnomAD-4.0.0 1.59961E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.44163E-05 0
D/E 8537 Ig-70 82 None 0.3536 None 0.063 N 0.345 0.072 0.333154297509 gnomAD-4.0.0 1.36895E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.3151E-05
D/N 8537 Ig-70 82 rs2077605401 0.177 None 0.993 N 0.581 0.337 0.513112959101 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/T 8631 Ig-71 83 rs769720173 0.1135 -0.694 0.483 D 0.492 0.208 0.318828661733 gnomAD-2.1.1 2.42E-05 None None None None N None 0 0 None 0 3.3415E-04 None 0 None 0 0 0
A/T 8631 Ig-71 83 rs769720173 0.1135 -0.694 0.483 D 0.492 0.208 0.318828661733 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92753E-04 None 0 0 0 0 0
A/T 8631 Ig-71 83 rs769720173 0.1135 -0.694 0.483 D 0.492 0.208 0.318828661733 gnomAD-4.0.0 8.98124E-06 None None None None N None 0 0 None 0 1.69779E-04 None 0 0 0 0 0
D/E 8724 Ig-72 82 rs752485826 0.3091 -0.314 0.001 D 0.291 0.095 0.302459207581 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.94E-06 0
D/E 8724 Ig-72 82 rs752485826 0.3091 -0.314 0.001 D 0.291 0.095 0.302459207581 gnomAD-4.0.0 6.84888E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00218E-07 0 0
D/N 8724 Ig-72 82 rs756034176 0.1402 -0.677 0.017 N 0.294 0.232 0.313518423057 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 0 None 6.6E-05 None 0 8.95E-06 0
D/N 8724 Ig-72 82 rs756034176 0.1402 -0.677 0.017 N 0.294 0.232 0.313518423057 gnomAD-4.0.0 4.79472E-06 None None None None I None 2.99168E-05 0 None 0 0 None 0 0 9.00278E-07 5.81788E-05 0
D/Y 8724 Ig-72 82 rs756034176 0.4036 0.102 0.995 D 0.826 0.464 0.588745719774 gnomAD-2.1.1 8.09E-06 None None None None I None 0 0 None 0 0 None 6.6E-05 None 0 0 0
D/Y 8724 Ig-72 82 rs756034176 0.4036 0.102 0.995 D 0.826 0.464 0.588745719774 gnomAD-4.0.0 6.84961E-06 None None None None I None 0 0 None 0 0 None 0 0 5.40167E-06 4.6543E-05 0
Q/K 8818 Ig-73 83 rs2077133872 0.1023 None 0.556 N 0.291 0.233 0.273938319068 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
Q/K 8818 Ig-73 83 rs2077133872 0.1023 None 0.556 N 0.291 0.233 0.273938319068 gnomAD-4.0.0 2.56377E-06 None None None None I None 0 0 None 0 0 None 0 0 4.78964E-06 0 0
D/V 9007 Ig-75 82 rs1456494692 0.2816 0.116 0.998 N 0.779 0.387 0.631910935859 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
D/V 9007 Ig-75 82 rs1456494692 0.2816 0.116 0.998 N 0.779 0.387 0.631910935859 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
D/V 9007 Ig-75 82 rs1456494692 0.2816 0.116 0.998 N 0.779 0.387 0.631910935859 gnomAD-4.0.0 1.31404E-05 None None None None N None 4.82369E-05 0 None 0 0 None 0 0 0 0 0
A/S 9100 Ig-76 82 rs746094812 0.0984 -0.795 0.012 N 0.429 0.107 0.159798565429 gnomAD-2.1.1 2.82E-05 None None None None N None 0 0 None 0 0 None 2.28923E-04 None 0 0 0
A/S 9100 Ig-76 82 rs746094812 0.0984 -0.795 0.012 N 0.429 0.107 0.159798565429 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
A/S 9100 Ig-76 82 rs746094812 0.0984 -0.795 0.012 N 0.429 0.107 0.159798565429 gnomAD-4.0.0 1.48737E-05 None None None None N None 0 0 None 0 0 None 0 0 0 2.63522E-04 0
D/H 9193 Ig-77 82 None 0.8637 None 1.0 N 0.778 0.505 0.552698843619 gnomAD-4.0.0 6.84252E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65651E-05
D/N 9193 Ig-77 82 rs2076787614 0.4014 None 0.999 N 0.773 0.376 0.541512316009 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92604E-04 None 0 0 0 0 0
D/Y 9193 Ig-77 82 rs2076787614 0.7579 None 1.0 D 0.846 0.545 0.560642594899 gnomAD-4.0.0 2.05276E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69855E-06 0 0
V/A 9286 Ig-78 82 rs769642697 0.0993 -1.536 0.002 N 0.121 0.212 0.542318960711 gnomAD-2.1.1 4.09E-06 None None None None N None 0 0 None 0 0 None 3.38E-05 None 0 0 0
V/A 9286 Ig-78 82 rs769642697 0.0993 -1.536 0.002 N 0.121 0.212 0.542318960711 gnomAD-4.0.0 2.06466E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.53349E-05 0
V/D 9286 Ig-78 82 rs769642697 0.2573 None 0.891 N 0.652 0.4 0.852490477632 gnomAD-4.0.0 1.37644E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80742E-06 0 0
V/F 9286 Ig-78 82 rs777547707 0.1865 -1.054 0.966 D 0.563 0.471 0.833848131578 gnomAD-2.1.1 2.45E-05 None None None None N None 0 0 None 0 2.79018E-04 None 0 None 0 0 1.6852E-04
V/F 9286 Ig-78 82 rs777547707 0.1865 -1.054 0.966 D 0.563 0.471 0.833848131578 gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 9.61908E-04 None 0 0 0 0 0
V/F 9286 Ig-78 82 rs777547707 0.1865 -1.054 0.966 D 0.563 0.471 0.833848131578 gnomAD-4.0.0 7.72553E-05 None None None None N None 0 0 None 0 2.70258E-03 None 0 0 8.51409E-07 0 3.22186E-05
V/I 9286 Ig-78 82 None 0.0881 None 0.625 N 0.461 0.167 None gnomAD-4.0.0 6.88289E-07 None None None None N None 0 0 None 0 0 None 0 0 9.03757E-07 0 0
V/L 9286 Ig-78 82 rs777547707 0.257 None 0.625 N 0.395 0.189 0.428976297845 gnomAD-4.0.0 6.88289E-07 None None None None N None 0 0 None 0 0 None 0 0 9.03757E-07 0 0
A/G 9382 Ig-79 82 None 0.2449 None 0.989 None 0.529 0.471 0.503248607038 gnomAD-4.0.0 3.23474E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.94724E-05 0
D/A 9478 Ig-80 82 rs1553887887 0.274 None 0.379 None 0.591 0.227 0.409533910539 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
D/N 9478 Ig-80 82 rs1201727409 0.2313 None 0.379 None 0.493 0.353 0.271763555656 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/N 9478 Ig-80 82 rs1201727409 0.2313 None 0.379 None 0.493 0.353 0.271763555656 gnomAD-4.0.0 6.57142E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46985E-05 0 0
D/Y 9478 Ig-80 82 None 0.4814 None 0.681 None 0.688 0.458 0.689224899524 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
D/G 9671 Ig-82 82 rs530627450 0.4497 -1.279 0.989 None 0.683 0.532 0.440498838766 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
D/G 9671 Ig-82 82 rs530627450 0.4497 -1.279 0.989 None 0.683 0.532 0.440498838766 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 0 None None None 1E-03 None
D/G 9671 Ig-82 82 rs530627450 0.4497 -1.279 0.989 None 0.683 0.532 0.440498838766 gnomAD-4.0.0 6.56435E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.07211E-04 0
I/F 9780 Ig-83 83 rs916661752 0.6191 None 0.982 None 0.617 0.408 0.460526725402 gnomAD-4.0.0 3.18216E-06 None None None None I None 0 0 None 0 0 None 0 0 5.71585E-06 0 0
I/T 9780 Ig-83 83 None 0.4621 None 0.939 None 0.635 0.343 0.625546071808 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
A/V 10159 Ig-86 82 rs1468822039 0.8081 -0.856 1.0 None 0.605 0.317 0.571034400148 gnomAD-2.1.1 7.13E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
A/V 10159 Ig-86 82 rs1468822039 0.8081 -0.856 1.0 None 0.605 0.317 0.571034400148 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/V 10159 Ig-86 82 rs1468822039 0.8081 -0.856 1.0 None 0.605 0.317 0.571034400148 gnomAD-4.0.0 2.56175E-06 None None None None N None 3.38306E-05 0 None 0 0 None 0 0 0 0 0
K/N 13767 Ig-87 84 None 0.8973 None 0.999 N 0.667 0.284 0.258283824007 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
A/T 13956 Ig-89 81 rs1176642239 0.7898 -1.577 0.999 D 0.701 0.452 0.589992848803 gnomAD-2.1.1 4.2E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.34E-06 0
A/T 13956 Ig-89 81 rs1176642239 0.7898 -1.577 0.999 D 0.701 0.452 0.589992848803 gnomAD-4.0.0 1.60727E-06 None None None None N None 0 0 None 0 0 None 0 0 2.88264E-06 0 0
A/V 13956 Ig-89 81 rs2060324765 0.8653 None 0.999 D 0.663 0.47 0.61427494375 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/G 14045 Ig-90 81 None 0.4019 None 0.262 N 0.299 0.224 0.284539287134 gnomAD-4.0.0 6.84505E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99766E-07 0 0
A/V 14045 Ig-90 81 None 0.9916 None 0.999 D 0.626 0.347 0.479208069955 gnomAD-4.0.0 1.36901E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79953E-06 0 0
A/G 14399 Ig-94 81 None 0.4178 None 0.999 D 0.628 0.365 0.242244723065 gnomAD-4.0.0 1.59371E-06 None None None None N None 0 0 None 0 0 None 1.88388E-05 0 0 0 0
A/P 14399 Ig-94 81 None 0.9907 None 1.0 D 0.862 0.463 0.304435445954 gnomAD-4.0.0 1.59362E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86171E-06 0 0
G/S 14488 Ig-95 81 None 0.1815 None 0.955 D 0.563 0.359 0.375861065471 gnomAD-4.0.0 6.84494E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.16125E-05 0
A/V 14755 Ig-98 81 None 0.8002 None 0.999 D 0.617 0.427 0.344017737713 gnomAD-4.0.0 1.08029E-05 None None None None N None 0 0 None 0 0 None 0 0 1.18125E-05 0 0
A/G 14844 Ig-99 80 rs1053826157 0.2581 None 1.0 D 0.551 0.393 0.267299060538 gnomAD-4.0.0 2.06323E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80449E-06 0 1.66578E-05
A/T 14844 Ig-99 80 rs772053966 0.6197 -1.322 1.0 D 0.686 0.434 0.24896430686 gnomAD-2.1.1 2.47E-05 None None None None N None 0 9.05E-05 None 0 0 None 0 None 0 2.71E-05 0
A/T 14844 Ig-99 80 rs772053966 0.6197 -1.322 1.0 D 0.686 0.434 0.24896430686 gnomAD-4.0.0 1.10051E-05 None None None None N None 3.04395E-05 6.86845E-05 None 0 2.55076E-05 None 0 0 9.02335E-06 0 1.66567E-05
C/R 14933 Ig-100 81 rs1238423083 0.9338 -0.275 0.984 N 0.793 0.342 0.220303561663 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
C/R 14933 Ig-100 81 rs1238423083 0.9338 -0.275 0.984 N 0.793 0.342 0.220303561663 gnomAD-4.0.0 1.59414E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43386E-05 0
C/Y 14933 Ig-100 81 None 0.9398 None 0.995 N 0.751 0.22 0.384752662912 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/S 15022 Ig-101 81 rs1296403453 0.5496 -0.928 1.0 N 0.705 0.416 0.168933306366 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 9.98E-05 0 None 0 None 0 0 0
G/S 15022 Ig-101 81 rs1296403453 0.5496 -0.928 1.0 N 0.705 0.416 0.168933306366 gnomAD-4.0.0 1.59509E-06 None None None None N None 0 0 None 4.78057E-05 0 None 0 0 0 0 0
D/G 15378 Ig-105 77 rs1443484418 0.4019 -0.512 0.996 N 0.489 0.305 0.215109475489 gnomAD-2.1.1 4.04E-06 None None None None N None 6.48E-05 0 None 0 0 None 0 None 0 0 0
D/G 15378 Ig-105 77 rs1443484418 0.4019 -0.512 0.996 N 0.489 0.305 0.215109475489 gnomAD-4.0.0 1.59502E-06 None None None None N None 5.68958E-05 0 None 0 0 None 0 0 0 0 0
D/H 15378 Ig-105 77 rs1301703106 0.5007 None 1.0 N 0.664 0.297 0.246773566709 gnomAD-4.0.0 1.59506E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86494E-06 0 0
D/N 15378 Ig-105 77 rs1301703106 0.1835 0.066 0.996 N 0.502 0.278 0.215109475489 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
D/N 15378 Ig-105 77 rs1301703106 0.1835 0.066 0.996 N 0.502 0.278 0.215109475489 gnomAD-4.0.0 1.59506E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86494E-06 0 0
A/T 15471 Ig-106 81 None 0.9037 None 1.0 D 0.679 0.642 0.726466338024 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
A/V 15471 Ig-106 81 rs1268534567 0.9621 0.277 1.0 D 0.585 0.684 0.765948534306 gnomAD-2.1.1 4.08E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.04E-06 0
A/V 15471 Ig-106 81 rs1268534567 0.9621 0.277 1.0 D 0.585 0.684 0.765948534306 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/V 15471 Ig-106 81 rs1268534567 0.9621 0.277 1.0 D 0.585 0.684 0.765948534306 gnomAD-4.0.0 2.57302E-06 None None None None N None 0 0 None 0 0 None 0 0 4.80141E-06 0 0
A/T 15646 Ig-108 79 None 0.1099 None 0.989 N 0.655 0.423 0.405422107966 gnomAD-4.0.0 8.40225E-06 None None None None N None 0 0 None 0 0 None 0 0 9.18751E-06 0 0
A/T 16340 Ig-110 79 rs1465666542 0.3093 -0.37 1.0 N 0.716 0.465 0.651728555758 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 1.00827E-04 0 None 0 None 0 0 0
A/P 17036 Ig-111 82 rs541142672 0.938 None 0.773 D 0.519 0.505 0.530011692926 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/P 17036 Ig-111 82 rs541142672 0.938 None 0.773 D 0.519 0.505 0.530011692926 gnomAD-4.0.0 2.56628E-06 None None None None I None 1.69428E-05 0 None 0 0 None 0 0 2.39709E-06 0 0
A/V 17358 Ig-112 108 None 0.2286 None 0.235 N 0.347 0.289 0.480123561213 gnomAD-4.0.0 7.2825E-07 None None None None I None 0 0 None 0 0 None 0 0 9.32151E-07 0 0
K/N 17753 Ig-113 77 rs1456581218 0.7761 0.4 1.0 N 0.747 0.435 0.234412748748 gnomAD-2.1.1 6.38E-05 None None None None I None 2.29568E-04 0 None 0 0 None 0 None 0 0 0
K/N 17753 Ig-113 77 rs1456581218 0.7761 0.4 1.0 N 0.747 0.435 0.234412748748 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
K/N 17753 Ig-113 77 rs1456581218 0.7761 0.4 1.0 N 0.747 0.435 0.234412748748 gnomAD-4.0.0 6.57782E-06 None None None None I None 2.41278E-05 0 None 0 0 None 0 0 0 0 0
K/R 17753 Ig-113 77 None 0.111 None 0.999 D 0.617 0.352 0.412849826617 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
V/L 18054 Ig-114 87 rs200968679 0.2949 -0.555 0.005 N 0.153 0.181 None gnomAD-2.1.1 1.39062E-04 None None None None N None 4.15E-05 0 None 0 0 None 0 None 0 2.95669E-04 0
V/L 18054 Ig-114 87 rs200968679 0.2949 -0.555 0.005 N 0.153 0.181 None gnomAD-3.1.2 1.25021E-04 None None None None N None 2.41E-05 0 0 0 0 None 0 0 2.6494E-04 0 0
V/L 18054 Ig-114 87 rs200968679 0.2949 -0.555 0.005 N 0.153 0.181 None gnomAD-4.0.0 2.30265E-04 None None None None N None 4.02868E-05 0 None 0 0 None 3.14594E-05 0 2.94936E-04 1.11595E-05 2.74344E-04
K/N 18468 Ig-115 87 None 0.7184 None 1.0 N 0.697 0.406 0.294206760003 gnomAD-4.0.0 6.87648E-07 None None None None I None 0 0 None 0 0 None 0 0 9.01122E-07 0 0
K/R 18468 Ig-115 87 None 0.1098 None 0.999 N 0.587 0.298 0.391470661076 gnomAD-4.0.0 1.60985E-06 None None None None I None 0 0 None 0 0 None 0 0 2.875E-06 0 0
A/T 18773 Ig-116 86 None 0.0818 None 0.939 N 0.549 0.414 0.444807159249 gnomAD-4.0.0 1.64746E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.5223E-05 0
R/G 19468 Ig-118 78 rs2050849448 0.58 None 0.217 N 0.485 0.279 0.431379191433 gnomAD-4.0.0 1.5919E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43386E-05 0
A/V 20558 Ig-121 80 None 0.1985 None 1.0 N 0.681 0.412 0.461759001683 gnomAD-4.0.0 1.59271E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43361E-05 0
F/L 20853 Ig-122 85 None 0.9403 None 0.999 N 0.567 0.416 0.531342499125 gnomAD-4.0.0 1.59195E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85909E-06 0 0
F/S 20853 Ig-122 85 rs375844494 0.5481 -1.58 1.0 N 0.783 0.504 None gnomAD-2.1.1 1.07E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.35E-05 0
F/S 20853 Ig-122 85 rs375844494 0.5481 -1.58 1.0 N 0.783 0.504 None gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
F/S 20853 Ig-122 85 rs375844494 0.5481 -1.58 1.0 N 0.783 0.504 None gnomAD-4.0.0 1.11568E-05 None None None None I None 0 0 None 0 0 None 0 0 1.4411E-05 0 1.60149E-05
D/E 21548 Ig-124 80 None 0.1731 None 0.425 N 0.335 0.069 0.343560092441 gnomAD-4.0.0 1.60851E-06 None None None None N None 0 0 None 0 2.77747E-05 None 0 0 0 0 0
D/Y 21548 Ig-124 80 rs749070255 0.2923 -0.305 0.975 N 0.589 0.414 0.686361129187 gnomAD-2.1.1 7.26E-06 None None None None N None 4.15E-05 0 None 0 0 None 0 None 0 7.9E-06 0
D/Y 21548 Ig-124 80 rs749070255 0.2923 -0.305 0.975 N 0.589 0.414 0.686361129187 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
D/Y 21548 Ig-124 80 rs749070255 0.2923 -0.305 0.975 N 0.589 0.414 0.686361129187 gnomAD-4.0.0 1.43147E-05 None None None None N None 1.3434E-05 0 None 0 0 None 0 0 1.87006E-05 0 0
K/N 22343 Ig-126 79 None 0.8124 None 1.0 N 0.723 0.384 0.317378411342 gnomAD-4.0.0 1.20037E-06 None None None None I None 0 0 None 0 2.75634E-04 None 0 0 0 0 0
K/R 22632 Ig-127 73 None 0.0829 None 0.999 N 0.615 0.237 0.346315397577 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/T 23424 Ig-129 80 None 0.5425 None 1.0 N 0.681 0.449 0.543824025769 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 23715 Ig-130 79 rs759011433 0.0913 -0.362 0.014 N 0.325 0.227 0.42989457901 gnomAD-2.1.1 1.79E-05 None None None None I None 0 2.84E-05 None 0 0 None 0 None 0 3.13E-05 0
V/A 23715 Ig-130 79 rs759011433 0.0913 -0.362 0.014 N 0.325 0.227 0.42989457901 gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 0 1.9425E-04 None 0 0 2.94E-05 0 0
V/A 23715 Ig-130 79 rs759011433 0.0913 -0.362 0.014 N 0.325 0.227 0.42989457901 gnomAD-4.0.0 1.17783E-05 None None None None I None 0 3.33545E-05 None 0 2.23904E-05 None 0 1.65235E-04 1.27172E-05 0 0
V/D 23715 Ig-130 79 rs759011433 0.3875 -0.159 0.971 N 0.729 0.544 0.745999668302 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
V/D 23715 Ig-130 79 rs759011433 0.3875 -0.159 0.971 N 0.729 0.544 0.745999668302 gnomAD-4.0.0 2.05327E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69889E-06 0 0
A/P 24111 Ig-131 83 rs369671334 0.985 -0.121 0.991 N 0.764 0.533 None gnomAD-2.1.1 7.54E-05 None None None None N None 4.14E-05 2.86E-05 None 0 0 None 0 None 0 1.49099E-04 0
A/P 24111 Ig-131 83 rs369671334 0.985 -0.121 0.991 N 0.764 0.533 None gnomAD-3.1.2 7.23E-05 None None None None N None 2.41E-05 1.31027E-04 0 0 0 None 0 0 1.17668E-04 0 0
A/P 24111 Ig-131 83 rs369671334 0.985 -0.121 0.991 N 0.764 0.533 None gnomAD-4.0.0 4.5321E-05 None None None None N None 1.33672E-05 6.69882E-05 None 0 0 None 0 0 5.34768E-05 0 8.02259E-05
K/R 24508 Ig-132 78 rs1559416294 0.1318 None 0.944 N 0.581 0.33 0.4897983601 gnomAD-4.0.0 1.59229E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85984E-06 0 0
A/G 24797 Ig-133 82 None 0.1741 None 0.999 N 0.632 0.517 0.60525595389 gnomAD-4.0.0 1.36869E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79927E-06 0 0
A/S 24797 Ig-133 82 None 0.1061 None 0.999 D 0.635 0.345 0.495038369364 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/G 25193 Ig-134 83 rs1175414210 0.1976 -1.831 None D 0.163 0.203 0.337135696972 gnomAD-4.0.0 1.59231E-06 None None None None N None 0 2.28822E-05 None 0 0 None 0 0 0 0 0
R/S 25193 Ig-134 83 None 0.291 None 0.012 N 0.353 0.088 0.223146558224 gnomAD-4.0.0 1.59229E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85936E-06 0 0
K/N 25590 Ig-135 77 rs1707266415 0.8836 None 1.0 N 0.721 0.329 0.319686207203 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
K/N 25590 Ig-135 77 rs1707266415 0.8836 None 1.0 N 0.721 0.329 0.319686207203 gnomAD-4.0.0 6.57497E-06 None None None None N None 2.41313E-05 0 None 0 0 None 0 0 0 0 0
K/R 25590 Ig-135 77 rs1348119178 0.1044 0.046 0.999 D 0.571 0.292 0.520586239559 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
K/R 25590 Ig-135 77 rs1348119178 0.1044 0.046 0.999 D 0.571 0.292 0.520586239559 gnomAD-4.0.0 1.59207E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8599E-06 0 0
K/R 25879 Ig-136 82 None 0.0898 None 0.892 N 0.526 0.161 0.423716096872 gnomAD-4.0.0 1.59203E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85958E-06 0 0
K/E 26672 Ig-138 79 None 0.6504 None 0.999 D 0.66 0.386 0.403752378121 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/M 26672 Ig-138 79 rs765691452 0.5484 0.322 1.0 N 0.623 0.516 0.486636631601 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
K/M 26672 Ig-138 79 rs765691452 0.5484 0.322 1.0 N 0.623 0.516 0.486636631601 gnomAD-4.0.0 1.36853E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7991E-06 0 0
K/N 26672 Ig-138 79 rs762254728 0.8612 0.495 1.0 N 0.709 0.358 0.286081765059 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
K/N 26672 Ig-138 79 rs762254728 0.8612 0.495 1.0 N 0.709 0.358 0.286081765059 gnomAD-4.0.0 4.78987E-06 None None None None N None 0 0 None 0 0 None 0 0 6.29687E-06 0 0
A/E 26961 Ig-139 82 rs749194310 0.2768 -0.553 0.193 N 0.665 0.181 0.365703291355 gnomAD-2.1.1 8.06E-06 None None None None N None 6.47E-05 2.9E-05 None 0 0 None 0 None 0 0 0
A/E 26961 Ig-139 82 rs749194310 0.2768 -0.553 0.193 N 0.665 0.181 0.365703291355 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/E 26961 Ig-139 82 rs749194310 0.2768 -0.553 0.193 N 0.665 0.181 0.365703291355 gnomAD-4.0.0 2.47909E-06 None None None None N None 2.67023E-05 1.66778E-05 None 0 0 None 0 0 8.47679E-07 0 0
A/T 26961 Ig-139 82 rs779484612 0.0709 -0.634 0.001 N 0.218 0.116 0.209622950755 gnomAD-2.1.1 2.42E-05 None None None None N None 6.46E-05 1.45003E-04 None 0 0 None 0 None 0 0 0
A/T 26961 Ig-139 82 rs779484612 0.0709 -0.634 0.001 N 0.218 0.116 0.209622950755 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 26961 Ig-139 82 rs779484612 0.0709 -0.634 0.001 N 0.218 0.116 0.209622950755 gnomAD-4.0.0 6.19765E-06 None None None None N None 2.67023E-05 1.16744E-04 None 0 0 None 0 1.64528E-04 0 0 0
A/V 26961 Ig-139 82 rs749194310 0.0869 -0.171 0.003 N 0.217 0.102 0.293147016451 gnomAD-2.1.1 6.44E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.41161E-04 0
A/V 26961 Ig-139 82 rs749194310 0.0869 -0.171 0.003 N 0.217 0.102 0.293147016451 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 4.41E-05 0 4.78469E-04
A/V 26961 Ig-139 82 rs749194310 0.0869 -0.171 0.003 N 0.217 0.102 0.293147016451 gnomAD-4.0.0 2.31795E-04 None None None None N None 1.33511E-05 0 None 0 0 None 0 0 3.13641E-04 0 4.80384E-05
K/T 27358 Ig-140 81 rs1483331348 0.2039 0.024 0.988 N 0.676 0.391 0.42573502686 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
K/T 27358 Ig-140 81 rs1483331348 0.2039 0.024 0.988 N 0.676 0.391 0.42573502686 gnomAD-4.0.0 2.05265E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69848E-06 0 0
K/N 27755 Ig-141 80 None 0.9352 None 0.99 N 0.677 0.365 0.307332253619 gnomAD-4.0.0 1.59287E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8601E-06 0 0
K/Q 27755 Ig-141 80 None 0.4203 None 0.99 N 0.689 0.401 0.370051654043 gnomAD-4.0.0 1.59297E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86022E-06 0 0
I/L 28044 Ig-142 82 rs369062122 0.0963 -0.45 None N 0.116 0.097 0.214338557667 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
I/L 28044 Ig-142 82 rs369062122 0.0963 -0.45 None N 0.116 0.097 0.214338557667 gnomAD-3.1.2 3.29E-05 None None None None N None 1.20616E-04 0 0 0 0 None 0 0 0 0 0
I/L 28044 Ig-142 82 rs369062122 0.0963 -0.45 None N 0.116 0.097 0.214338557667 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
I/L 28044 Ig-142 82 rs369062122 0.0963 -0.45 None N 0.116 0.097 0.214338557667 gnomAD-4.0.0 6.81736E-06 None None None None N None 7.99637E-05 0 None 0 8.93895E-05 None 0 0 0 0 1.60092E-05
I/M 28044 Ig-142 82 None 0.082 None 0.001 N 0.285 0.048 0.390060412749 gnomAD-4.0.0 1.59208E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43324E-05 0
I/T 28044 Ig-142 82 rs1004500080 0.0848 -1.05 None N 0.183 0.086 0.33340067248 gnomAD-2.1.1 7.16E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
I/T 28044 Ig-142 82 rs1004500080 0.0848 -1.05 None N 0.183 0.086 0.33340067248 gnomAD-3.1.2 2.63E-05 None None None None N None 9.65E-05 0 0 0 0 None 0 0 0 0 0
I/T 28044 Ig-142 82 rs1004500080 0.0848 -1.05 None N 0.183 0.086 0.33340067248 gnomAD-4.0.0 5.57836E-06 None None None None N None 8.0094E-05 0 None 0 0 None 0 0 2.54302E-06 0 0
I/V 28044 Ig-142 82 rs369062122 0.0585 -0.666 None N 0.121 0.074 None gnomAD-2.1.1 2.51E-05 None None None None N None 1.24059E-04 0 None 0 0 None 6.54E-05 None 8.02E-05 0 0
I/V 28044 Ig-142 82 rs369062122 0.0585 -0.666 None N 0.121 0.074 None gnomAD-3.1.2 3.94E-05 None None None None N None 1.44739E-04 0 0 0 0 None 0 0 0 0 0
I/V 28044 Ig-142 82 rs369062122 0.0585 -0.666 None N 0.121 0.074 None gnomAD-4.0.0 8.05747E-06 None None None None N None 1.06792E-04 0 None 0 0 None 3.12598E-05 0 0 3.29424E-05 0
R/L 28439 Ig-143 82 rs764437671 0.2881 0.305 0.922 N 0.644 0.385 0.617917861134 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
R/L 28439 Ig-143 82 rs764437671 0.2881 0.305 0.922 N 0.644 0.385 0.617917861134 gnomAD-4.0.0 1.23172E-05 None None None None I None 0 0 None 0 0 None 0 0 1.61908E-05 0 0
R/P 28439 Ig-143 82 None 0.9409 None 0.988 N 0.739 0.517 0.546693616777 gnomAD-4.0.0 1.36858E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79898E-06 0 0
R/Q 28439 Ig-143 82 rs764437671 0.1289 0.112 0.989 D 0.643 0.288 None gnomAD-2.1.1 3.22E-05 None None None None I None 4.13E-05 5.67E-05 None 0 1.03125E-04 None 0 None 0 3.13E-05 0
R/Q 28439 Ig-143 82 rs764437671 0.1289 0.112 0.989 D 0.643 0.288 None gnomAD-3.1.2 7.23E-05 None None None None I None 2.41E-05 1.31062E-04 0 0 5.79598E-04 None 0 0 5.88E-05 0 4.77555E-04
R/Q 28439 Ig-143 82 rs764437671 0.1289 0.112 0.989 D 0.643 0.288 None gnomAD-4.0.0 2.60284E-05 None None None None I None 2.66546E-05 8.33528E-05 None 0 1.11702E-04 None 0 0 1.61049E-05 6.58892E-05 8.00435E-05
R/W 28439 Ig-143 82 rs757653038 0.2911 -0.519 1.0 N 0.753 0.484 None gnomAD-2.1.1 3.57E-05 None None None None I None 4.13E-05 1.98345E-04 None 0 5.16E-05 None 0 None 0 7.82E-06 0
R/W 28439 Ig-143 82 rs757653038 0.2911 -0.519 1.0 N 0.753 0.484 None gnomAD-3.1.2 1.97E-05 None None None None I None 2.41E-05 6.55E-05 0 0 0 None 0 0 1.47E-05 0 0
R/W 28439 Ig-143 82 rs757653038 0.2911 -0.519 1.0 N 0.753 0.484 None gnomAD-4.0.0 1.73534E-05 None None None None I None 1.33479E-05 1.5007E-04 None 0 0 None 0 0 1.35621E-05 1.09813E-05 1.60143E-05
A/V 28834 Ig-144 80 rs750913615 0.1012 0.074 0.698 N 0.465 0.274 0.519783508757 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 1.11383E-04 None 0 None 0 0 0
A/V 28834 Ig-144 80 rs750913615 0.1012 0.074 0.698 N 0.465 0.274 0.519783508757 gnomAD-4.0.0 2.05272E-06 None None None None I None 0 0 None 0 5.0388E-05 None 0 0 0 0 1.65667E-05
T/A 29126 Ig-145 82 rs773581788 0.0612 -1.193 0.121 N 0.301 0.095 0.144782658237 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
T/A 29126 Ig-145 82 rs773581788 0.0612 -1.193 0.121 N 0.301 0.095 0.144782658237 gnomAD-4.0.0 6.84347E-07 None None None None N None 0 0 None 0 2.51915E-05 None 0 0 0 0 0
T/I 29126 Ig-145 82 rs559269036 0.2044 -0.053 0.994 N 0.673 0.403 0.488757021912 gnomAD-2.1.1 8.05E-06 None None None None N None 0 2.9E-05 None 0 0 None 3.27E-05 None 0 0 0
T/I 29126 Ig-145 82 rs559269036 0.2044 -0.053 0.994 N 0.673 0.403 0.488757021912 gnomAD-3.1.2 1.31E-05 None None None None N None 0 1.30941E-04 0 0 0 None 0 0 0 0 0
T/I 29126 Ig-145 82 rs559269036 0.2044 -0.053 0.994 N 0.673 0.403 0.488757021912 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
T/I 29126 Ig-145 82 rs559269036 0.2044 -0.053 0.994 N 0.673 0.403 0.488757021912 gnomAD-4.0.0 3.84422E-06 None None None None N None 0 3.38788E-05 None 0 0 None 0 0 0 1.34034E-05 0
T/S 29126 Ig-145 82 rs559269036 0.1026 None 0.63 N 0.373 0.149 0.304435445954 gnomAD-4.0.0 6.84347E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99415E-07 0 0
A/G 29522 Ig-146 79 None 0.2633 None 0.998 N 0.609 0.402 0.583959843308 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 30213 Ig-148 82 rs114026724 0.0849 -1.54 None N 0.14 0.084 None gnomAD-2.1.1 1.93234E-03 None None None None I None 2.06731E-02 7.08255E-04 None 0 1.02543E-04 None 1.31044E-04 None 0 3.14E-05 7.03631E-04
I/T 30213 Ig-148 82 rs114026724 0.0849 -1.54 None N 0.14 0.084 None gnomAD-3.1.2 5.5565E-03 None None None None I None 1.94564E-02 1.44187E-03 0 0 0 None 0 0 7.35E-05 2.07297E-04 5.26316E-03
I/T 30213 Ig-148 82 rs114026724 0.0849 -1.54 None N 0.14 0.084 None 1000 genomes 6.58946E-03 None None None None I None 2.34E-02 2.9E-03 None None 0 0 None None None 0 None
I/T 30213 Ig-148 82 rs114026724 0.0849 -1.54 None N 0.14 0.084 None gnomAD-4.0.0 1.03813E-03 None None None None I None 1.8997E-02 9.50507E-04 None 3.37929E-05 6.68866E-05 None 0 3.3036E-04 7.2057E-05 9.88859E-05 1.48886E-03
K/Q 31005 Ig-150 79 None 0.2487 None 0.957 D 0.314 0.303 0.33835085245 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/N 32094 Ig-153 78 None 0.7883 None 1.0 N 0.707 0.427 0.245660935333 gnomAD-4.0.0 6.8426E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99526E-07 0 0
T/N 32388 Ig-154 82 None 0.1485 None 0.966 N 0.435 0.193 0.234412748748 gnomAD-4.0.0 1.59164E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02444E-05
V/I 33182 Ig-156 82 rs1060500530 0.0693 -0.692 0.001 N 0.126 0.126 0.42264334713 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 2.87687E-04 0 0
V/I 33182 Ig-156 82 rs1060500530 0.0693 -0.692 0.001 N 0.126 0.126 0.42264334713 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 9.42E-05 0 0 0 0
V/I 33182 Ig-156 82 rs1060500530 0.0693 -0.692 0.001 N 0.126 0.126 0.42264334713 gnomAD-4.0.0 2.47879E-06 None None None None N None 0 0 None 0 0 None 3.12471E-05 0 1.69519E-06 0 0
V/A 33279 Ig-157 77 rs770098799 0.1529 -1.51 0.998 N 0.455 0.335 0.61771375628 gnomAD-2.1.1 4.25E-06 None None None None I None 0 3.09E-05 None 0 0 None 0 None 0 0 0
V/A 33279 Ig-157 77 rs770098799 0.1529 -1.51 0.998 N 0.455 0.335 0.61771375628 gnomAD-4.0.0 3.30536E-06 None None None None I None 0 4.83419E-05 None 0 0 None 0 0 0 0 0
V/G 33279 Ig-157 77 rs770098799 0.4015 -1.942 1.0 N 0.753 0.576 0.899959819303 gnomAD-2.1.1 4.25E-06 None None None None I None 6.64E-05 0 None 0 0 None 0 None 0 0 0
V/G 33279 Ig-157 77 rs770098799 0.4015 -1.942 1.0 N 0.753 0.576 0.899959819303 gnomAD-3.1.2 1.31E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/G 33279 Ig-157 77 rs770098799 0.4015 -1.942 1.0 N 0.753 0.576 0.899959819303 gnomAD-4.0.0 3.96173E-06 None None None None I None 5.13699E-05 0 None 0 0 None 0 0 0 0 0
V/M 33579 Ig-158 84 rs1344390830 0.3247 -0.288 0.971 N 0.563 0.352 0.585593966701 gnomAD-2.1.1 3.18E-05 None None None None I None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
D/H 33678 Ig-159 83 rs1268811847 0.9422 -0.922 1.0 N 0.769 0.587 0.460438652622 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/H 33678 Ig-159 83 rs1268811847 0.9422 -0.922 1.0 N 0.769 0.587 0.460438652622 gnomAD-4.0.0 6.57065E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46968E-05 0 0
T/I 34445 Ig-162 83 rs778587344 0.5934 -0.336 0.062 N 0.435 0.226 0.284539287134 gnomAD-2.1.1 8.04E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 8.88E-06 0
T/I 34445 Ig-162 83 rs778587344 0.5934 -0.336 0.062 N 0.435 0.226 0.284539287134 gnomAD-3.1.2 1.31E-05 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 4.77555E-04
T/I 34445 Ig-162 83 rs778587344 0.5934 -0.336 0.062 N 0.435 0.226 0.284539287134 gnomAD-4.0.0 3.04481E-06 None None None None I None 0 6.14931E-05 None 0 0 None 0 0 1.20492E-06 0 3.40229E-05
A/V 35023 Ig-163 82 None 0.3232 None 0.885 N 0.565 0.266 0.490282680104 gnomAD-4.0.0 2.05246E-06 None None None None N None 0 0 None 0 0 None 0 0 8.994E-07 2.31868E-05 0
Q/H 35210 Ig-164 82 rs397517798 0.5988 None 0.998 N 0.579 0.241 0.367425347029 gnomAD-4.0.0 1.59087E-06 None None None None N None 5.65227E-05 0 None 0 0 None 0 0 0 0 0
Q/K 35210 Ig-164 82 None 0.1717 None 0.975 N 0.527 0.362 0.3349148499 gnomAD-4.0.0 4.10483E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39636E-06 0 0
V/G 35686 Ig-167 80 None 0.4693 None 0.497 N 0.611 0.312 0.661173699051 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
V/I 35686 Ig-167 80 rs751581732 0.0669 -0.09 0.002 N 0.109 0.167 0.137902524267 gnomAD-2.1.1 2.42E-05 None None None None I None 6.49E-05 0 None 0 0 None 0 None 0 4.46E-05 0
V/I 35686 Ig-167 80 rs751581732 0.0669 -0.09 0.002 N 0.109 0.167 0.137902524267 gnomAD-3.1.2 1.97E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 2.06868E-04 0
V/I 35686 Ig-167 80 rs751581732 0.0669 -0.09 0.002 N 0.109 0.167 0.137902524267 gnomAD-4.0.0 3.59507E-05 None None None None I None 4.0047E-05 0 None 0 1.33696E-04 None 1.56367E-05 0 3.98421E-05 1.09888E-05 0
C/R 35783 Ig-168 82 rs1389761673 0.7524 -0.585 1.0 N 0.85 0.528 0.75536777802 gnomAD-2.1.1 3.18E-05 None None None None I None 0 0 None 0 0 None 0 None 2.87687E-04 0 0
C/R 35783 Ig-168 82 rs1389761673 0.7524 -0.585 1.0 N 0.85 0.528 0.75536777802 gnomAD-4.0.0 1.59112E-06 None None None None I None 0 0 None 0 0 None 1.88246E-05 0 0 0 0
C/Y 35783 Ig-168 82 None 0.5877 None 1.0 N 0.85 0.51 0.772125089601 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/H 35980 Ig-169 84 None 0.7893 None 1.0 N 0.751 0.425 0.465633601861 gnomAD-4.0.0 1.59156E-06 None None None -1.341(OBSL1) 0.548(OBSCN) N None 0 0 None 0 0 None 0 0 2.85827E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.