Structural position:
- Domain Type: Ig
- Aligned Position: 175
- Secondary Structure Element: e
- Secondary Structure Region: β-strand G
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| L/M | 192 |
Ig-2 |
89 | None | 0.1689 | None | 0.343 | N | 0.609 | 0.186 | 0.689481310135 | gnomAD-4.0.0 | 6.84072E-07 | None | None | None | -0.43(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99306E-07 | 0 | 0 |
| L/R | 192 |
Ig-2 |
89 | rs1375853157 |
0.2255 | None | 0.779 | N | 0.729 | 0.408 | 0.782842511238 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | -0.603(TCAP) | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/R | 192 |
Ig-2 |
89 | rs1375853157 |
0.2255 | None | 0.779 | N | 0.729 | 0.408 | 0.782842511238 | gnomAD-4.0.0 | 2.56104E-06 | None | None | None | -0.603(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.7835E-06 | 0 | 0 |
| A/S | 1031 |
Ig-3 |
89 | rs748303934 |
0.1495 | None | 0.642 | N | 0.408 | 0.199 | 0.466059976078 | gnomAD-4.0.0 | 1.59367E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85791E-06 | 0 | 0 |
| A/T | 1031 |
Ig-3 |
89 | rs748303934 |
0.1934 | -0.752 | 0.642 | N | 0.392 | 0.224 | 0.465038187318 | gnomAD-2.1.1 | 7.1E-06 | None | None | None | None | N | None | 4.01E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.79E-06 | 0 |
| A/T | 1031 |
Ig-3 |
89 | rs748303934 |
0.1934 | -0.752 | 0.642 | N | 0.392 | 0.224 | 0.465038187318 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 1031 |
Ig-3 |
89 | rs748303934 |
0.1934 | -0.752 | 0.642 | N | 0.392 | 0.224 | 0.465038187318 | gnomAD-4.0.0 | 6.41279E-06 | None | None | None | None | N | None | 5.07511E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.7854E-06 | 0 | 0 |
| A/V | 1031 |
Ig-3 |
89 | None | 0.2935 | None | 0.002 | N | 0.111 | 0.27 | 0.562168935514 | gnomAD-4.0.0 | 1.59369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85786E-06 | 0 | 0 |
| Y/C | 1380 |
Ig-5 |
90 | None | 0.6089 | None | 1.0 | D | 0.757 | 0.459 | 0.730598733731 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| T/A | 1546 |
Ig-6 |
90 | None | 0.0958 | None | 0.64 | N | 0.531 | 0.31 | 0.394990421082 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/S | 1646 |
Ig-7 |
91 | rs2092286263 |
0.1323 | None | 0.999 | N | 0.584 | 0.372 | 0.44711355012 | gnomAD-4.0.0 | 1.59237E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85909E-06 | 0 | 0 |
| I/F | 1793 |
Ig-8 |
91 | None | 0.4267 | None | 0.998 | N | 0.624 | 0.255 | 0.705458290464 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/T | 1793 |
Ig-8 |
91 | rs746284395 |
0.4442 | -0.843 | 0.989 | N | 0.654 | 0.415 | 0.754311888153 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.63399E-04 | None | 0 | None | 0 | 8.82E-06 | 0 |
| I/T | 1793 |
Ig-8 |
91 | rs746284395 |
0.4442 | -0.843 | 0.989 | N | 0.654 | 0.415 | 0.754311888153 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/T | 1793 |
Ig-8 |
91 | rs746284395 |
0.4442 | -0.843 | 0.989 | N | 0.654 | 0.415 | 0.754311888153 | gnomAD-4.0.0 | 1.05716E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.3366E-04 | None | 0 | 0 | 9.32205E-06 | 0 | 0 |
| L/F | 2167 |
Ig-10 |
90 | None | 0.6629 | None | 1.0 | N | 0.654 | 0.342 | 0.798223434742 | gnomAD-4.0.0 | 2.05238E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52092E-05 | None | 0 | 0 | 1.79861E-06 | 0 | 0 |
| I/L | 2261 |
Ig-11 |
88 | rs755035176 |
0.0984 | -0.299 | None | N | 0.092 | 0.076 | 0.465806656444 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/L | 2261 |
Ig-11 |
88 | rs755035176 |
0.0984 | -0.299 | None | N | 0.092 | 0.076 | 0.465806656444 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 2261 |
Ig-11 |
88 | rs755035176 |
0.0984 | -0.299 | None | N | 0.092 | 0.076 | 0.465806656444 | gnomAD-4.0.0 | 1.23939E-06 | None | None | None | None | N | None | 1.33284E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09803E-05 | 0 |
| I/T | 2261 |
Ig-11 |
88 | rs751757338 |
0.0885 | -0.902 | 0.001 | N | 0.225 | 0.232 | 0.526842377483 | gnomAD-2.1.1 | 7.1E-06 | None | None | None | None | N | None | 4.01E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.78E-06 | 0 |
| I/T | 2261 |
Ig-11 |
88 | rs751757338 |
0.0885 | -0.902 | 0.001 | N | 0.225 | 0.232 | 0.526842377483 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 2261 |
Ig-11 |
88 | rs751757338 |
0.0885 | -0.902 | 0.001 | N | 0.225 | 0.232 | 0.526842377483 | gnomAD-4.0.0 | 3.7184E-06 | None | None | None | None | N | None | 2.66973E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54266E-06 | 0 | 1.60077E-05 |
| I/V | 2261 |
Ig-11 |
88 | None | 0.0806 | None | 0.019 | N | 0.25 | 0.059 | 0.572690963233 | gnomAD-4.0.0 | 6.84276E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99426E-07 | 0 | 0 |
| S/F | 2529 |
Ig-14 |
85 | rs1474453684 |
0.1456 | -0.872 | 0.773 | N | 0.401 | 0.257 | 0.43923137753 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.45E-05 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/F | 2529 |
Ig-14 |
85 | rs1474453684 |
0.1456 | -0.872 | 0.773 | N | 0.401 | 0.257 | 0.43923137753 | gnomAD-4.0.0 | 4.77266E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77516E-05 | None | 0 | 0 | 0 | 2.86558E-05 | 0 |
| T/A | 2616 |
Ig-15 |
84 | None | 0.1122 | None | 0.309 | N | 0.367 | 0.128 | 0.223146558224 | gnomAD-4.0.0 | 1.59109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85731E-06 | 0 | 0 |
| T/I | 2616 |
Ig-15 |
84 | None | 0.105 | None | 0.015 | N | 0.243 | 0.211 | 0.177238962908 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| T/P | 2616 |
Ig-15 |
84 | None | 0.5863 | None | 0.939 | D | 0.403 | 0.321 | 0.361958692863 | gnomAD-4.0.0 | 1.59109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| K/E | 2703 |
Ig-16 |
83 | rs2091436984 |
0.1682 | None | 0.896 | N | 0.557 | 0.303 | 0.297031009988 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 2703 |
Ig-16 |
83 | rs2091436984 |
0.1682 | None | 0.896 | N | 0.557 | 0.303 | 0.297031009988 | gnomAD-4.0.0 | 1.85881E-06 | None | None | None | None | N | None | 2.6688E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60061E-05 |
| K/N | 2703 |
Ig-16 |
83 | rs1561231770 |
0.2833 | None | 0.896 | N | 0.548 | 0.242 | 0.253205268125 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| K/T | 2703 |
Ig-16 |
83 | rs2091436696 |
0.1208 | None | 0.984 | N | 0.601 | 0.317 | 0.3349148499 | gnomAD-4.0.0 | 1.59078E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| F/I | 2878 |
Ig-18 |
84 | rs2091250841 |
0.3259 | None | 0.92 | N | 0.305 | 0.226 | 0.326345978581 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/I | 2878 |
Ig-18 |
84 | rs2091250841 |
0.3259 | None | 0.92 | N | 0.305 | 0.226 | 0.326345978581 | gnomAD-4.0.0 | 2.56115E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39172E-06 | 0 | 2.84188E-05 |
| F/L | 2878 |
Ig-18 |
84 | None | 0.8875 | None | 0.826 | N | 0.327 | 0.211 | 0.200317383148 | gnomAD-4.0.0 | 1.59047E-06 | None | None | None | None | N | None | 0 | 2.28645E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 2878 |
Ig-18 |
84 | rs2091250535 |
0.4455 | None | 0.704 | N | 0.319 | 0.238 | 0.655252992372 | gnomAD-4.0.0 | 1.36813E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99292E-07 | 0 | 1.65579E-05 |
| Y/H | 3052 |
Ig-20 |
84 | rs763833161 |
0.5196 | -0.35 | 0.003 | N | 0.151 | 0.08 | 0.1749357433 | gnomAD-2.1.1 | 3.58E-05 | None | None | None | None | N | None | 0 | 2.31468E-04 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| Y/H | 3052 |
Ig-20 |
84 | rs763833161 |
0.5196 | -0.35 | 0.003 | N | 0.151 | 0.08 | 0.1749357433 | gnomAD-4.0.0 | 1.64183E-05 | None | None | None | None | N | None | 0 | 2.01279E-04 | None | 0 | 0 | None | 0 | 0 | 1.34895E-05 | 0 | 0 |
| F/V | 3141 |
Ig-21 |
84 | rs1423594676 |
0.1479 | -0.845 | None | N | 0.1 | 0.087 | 0.190952846119 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 6.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/V | 3141 |
Ig-21 |
84 | rs1423594676 |
0.1479 | -0.845 | None | N | 0.1 | 0.087 | 0.190952846119 | gnomAD-4.0.0 | 1.59052E-06 | None | None | None | None | N | None | 5.65163E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/C | 3232 |
Ig-22 |
86 | rs537306539 |
0.2607 | -0.1 | 0.946 | N | 0.285 | 0.141 | 0.422524665647 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 4.65E-05 | 0 |
| Y/C | 3232 |
Ig-22 |
86 | rs537306539 |
0.2607 | -0.1 | 0.946 | N | 0.285 | 0.141 | 0.422524665647 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 3232 |
Ig-22 |
86 | rs537306539 |
0.2607 | -0.1 | 0.946 | N | 0.285 | 0.141 | 0.422524665647 | gnomAD-4.0.0 | 1.4279E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.61413E-05 | 3.29518E-05 | 1.6039E-05 |
| Y/S | 3232 |
Ig-22 |
86 | rs537306539 |
0.3426 | -0.806 | 0.175 | N | 0.351 | 0.145 | 0.355658859761 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Y/S | 3232 |
Ig-22 |
86 | rs537306539 |
0.3426 | -0.806 | 0.175 | N | 0.351 | 0.145 | 0.355658859761 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| Y/S | 3232 |
Ig-22 |
86 | rs537306539 |
0.3426 | -0.806 | 0.175 | N | 0.351 | 0.145 | 0.355658859761 | gnomAD-4.0.0 | 6.56625E-06 | None | None | None | None | N | None | 2.40547E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 3327 |
Ig-23 |
89 | rs1561162422 |
0.102 | None | 0.473 | N | 0.515 | 0.258 | 0.626644753645 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.93E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/L | 3327 |
Ig-23 |
89 | rs1561162422 |
0.102 | None | 0.473 | N | 0.515 | 0.258 | 0.626644753645 | gnomAD-4.0.0 | 1.59069E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76554E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 3432 |
Ig-24 |
88 | rs1392831001 |
0.0978 | -0.202 | None | N | 0.071 | 0.115 | 0.146414634003 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| S/N | 3432 |
Ig-24 |
88 | rs1392831001 |
0.0978 | -0.202 | None | N | 0.071 | 0.115 | 0.146414634003 | gnomAD-4.0.0 | 4.7724E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71409E-06 | 0 | 3.02243E-05 |
| S/T | 3432 |
Ig-24 |
88 | rs1392831001 |
0.0699 | None | None | N | 0.073 | 0.087 | 0.117506650769 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 3432 |
Ig-24 |
88 | rs1392831001 |
0.0699 | None | None | N | 0.073 | 0.087 | 0.117506650769 | gnomAD-4.0.0 | 6.5716E-06 | None | None | None | None | N | None | 2.41301E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 3555 |
Ig-25 |
91 | None | 0.1584 | None | None | None | None | 0.269 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/G | 3748 |
Ig-26 |
89 | rs2086888986 |
0.0964 | None | None | None | None | 0.189 | None | gnomAD-4.0.0 | 6.86223E-07 | None | None | None | None | I | None | 2.99616E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 4693 |
Ig-29 |
88 | None | 0.1403 | None | 0.992 | D | 0.464 | 0.363 | None | gnomAD-4.0.0 | 7.35882E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.4021E-07 | 0 | 0 |
| T/I | 4788 |
Ig-30 |
89 | None | 0.1858 | None | 0.606 | N | 0.293 | 0.251 | 0.40318662893 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/N | 4883 |
Ig-31 |
89 | None | 0.104 | None | None | N | 0.221 | 0.119 | None | gnomAD-4.0.0 | 1.59151E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85822E-06 | 0 | 0 |
| I/S | 4883 |
Ig-31 |
89 | rs369548127 |
0.1322 | -1.259 | None | N | 0.14 | 0.087 | 0.219573609325 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/S | 4883 |
Ig-31 |
89 | rs369548127 |
0.1322 | -1.259 | None | N | 0.14 | 0.087 | 0.219573609325 | gnomAD-4.0.0 | 1.59151E-06 | None | None | None | None | N | None | 0 | 2.28707E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 4883 |
Ig-31 |
89 | rs369548127 |
0.0893 | -1.063 | None | N | 0.123 | 0.107 | 0.181679512989 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| I/T | 4883 |
Ig-31 |
89 | rs369548127 |
0.0893 | -1.063 | None | N | 0.123 | 0.107 | 0.181679512989 | gnomAD-4.0.0 | 3.18301E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.55556E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 4976 |
Ig-32 |
89 | None | 0.1032 | None | 0.188 | N | 0.398 | 0.254 | 0.0884992946249 | gnomAD-4.0.0 | 7.01756E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.11057E-07 | 0 | 0 |
| V/L | 5070 |
Ig-33 |
90 | None | 0.162 | None | 0.454 | N | 0.346 | 0.059 | 0.476051820916 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/T | 5256 |
Ig-35 |
89 | rs773177460 |
0.0623 | -0.672 | None | N | 0.111 | 0.109 | 0.374970422459 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.67E-05 | 0 | 0 |
| I/T | 5256 |
Ig-35 |
89 | rs773177460 |
0.0623 | -0.672 | None | N | 0.111 | 0.109 | 0.374970422459 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 9.41E-05 | 0 | 0 | 0 | 0 |
| I/T | 5256 |
Ig-35 |
89 | rs773177460 |
0.0623 | -0.672 | None | N | 0.111 | 0.109 | 0.374970422459 | gnomAD-4.0.0 | 2.48319E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.56348E-05 | 0 | 1.69832E-06 | 0 | 1.60514E-05 |
| T/A | 5349 |
Ig-36 |
89 | rs2080869632 |
0.1081 | None | 0.9 | D | 0.539 | 0.344 | 0.36036328697 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 5349 |
Ig-36 |
89 | rs2080869632 |
0.1081 | None | 0.9 | D | 0.539 | 0.344 | 0.36036328697 | gnomAD-4.0.0 | 1.25084E-06 | None | None | None | None | I | None | 0 | 1.69285E-05 | None | 0 | 0 | None | 0 | 0 | 8.52979E-07 | 0 | 0 |
| T/I | 5349 |
Ig-36 |
89 | None | 0.1958 | None | 0.997 | N | 0.645 | 0.42 | 0.600985507913 | gnomAD-4.0.0 | 1.63129E-06 | None | None | None | None | I | None | 5.75573E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 5349 |
Ig-36 |
89 | None | 0.1327 | None | 0.63 | N | 0.347 | 0.308 | 0.296329037015 | gnomAD-4.0.0 | 6.91229E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.05525E-07 | 0 | 0 |
| I/L | 5445 |
Ig-37 |
89 | rs1360601333 |
0.0879 | -0.418 | 0.002 | N | 0.192 | 0.088 | 0.420199648628 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| I/L | 5445 |
Ig-37 |
89 | rs1360601333 |
0.0879 | -0.418 | 0.002 | N | 0.192 | 0.088 | 0.420199648628 | gnomAD-4.0.0 | 2.05861E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70525E-06 | 0 | 0 |
| I/M | 5445 |
Ig-37 |
89 | rs1485054332 |
0.0821 | -0.488 | 0.171 | N | 0.289 | 0.173 | 0.440182696023 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| I/T | 5445 |
Ig-37 |
89 | rs1286622718 |
0.0791 | -0.849 | None | N | 0.115 | 0.273 | 0.538929202391 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| I/T | 5445 |
Ig-37 |
89 | rs1286622718 |
0.0791 | -0.849 | None | N | 0.115 | 0.273 | 0.538929202391 | gnomAD-4.0.0 | 1.6019E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.88136E-06 | 0 | 0 |
| I/R | 5632 |
Ig-39 |
90 | None | 0.1524 | None | 0.863 | N | 0.493 | 0.374 | 0.812764335004 | gnomAD-4.0.0 | 6.88696E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0453E-07 | 0 | 0 |
| I/T | 5632 |
Ig-39 |
90 | rs727504971 |
0.0797 | None | 0.003 | N | 0.179 | 0.258 | 0.659973416392 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 5632 |
Ig-39 |
90 | rs727504971 |
0.0797 | None | 0.003 | N | 0.179 | 0.258 | 0.659973416392 | gnomAD-4.0.0 | 1.87008E-06 | None | None | None | None | N | None | 2.67709E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.52101E-07 | 0 | 0 |
| T/I | 5725 |
Ig-40 |
89 | None | 0.1048 | None | 0.896 | N | 0.412 | 0.314 | 0.321393169273 | gnomAD-4.0.0 | 1.60281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.88455E-06 | 0 | 0 |
| T/N | 5725 |
Ig-40 |
89 | rs776879170 |
0.1023 | -0.652 | 0.379 | D | 0.395 | 0.226 | 0.248417906384 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.3238E-04 | None | 0 | 0 | 0 |
| T/N | 5725 |
Ig-40 |
89 | rs776879170 |
0.1023 | -0.652 | 0.379 | D | 0.395 | 0.226 | 0.248417906384 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| T/N | 5725 |
Ig-40 |
89 | rs776879170 |
0.1023 | -0.652 | 0.379 | D | 0.395 | 0.226 | 0.248417906384 | gnomAD-4.0.0 | 1.54628E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.48116E-04 | 2.85796E-05 |
| T/S | 5725 |
Ig-40 |
89 | rs781556763 |
0.0913 | None | 0.016 | N | 0.177 | 0.133 | 0.0401082797425 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.99E-06 | 0 |
| T/S | 5725 |
Ig-40 |
89 | rs781556763 |
0.0913 | None | 0.016 | N | 0.177 | 0.133 | 0.0401082797425 | gnomAD-4.0.0 | 3.20556E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.76961E-06 | 0 | 0 |
| S/L | 5818 |
Ig-41 |
89 | rs749007462 |
0.0773 | -0.423 | 0.669 | N | 0.461 | 0.288 | 0.478828542108 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 0 | 0 |
| S/L | 5818 |
Ig-41 |
89 | rs749007462 |
0.0773 | -0.423 | 0.669 | N | 0.461 | 0.288 | 0.478828542108 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07641E-04 | 0 |
| S/L | 5818 |
Ig-41 |
89 | rs749007462 |
0.0773 | -0.423 | 0.669 | N | 0.461 | 0.288 | 0.478828542108 | gnomAD-4.0.0 | 6.19769E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09823E-04 | 0 |
| N/H | 5911 |
Ig-42 |
89 | rs781725187 |
0.0863 | -0.731 | 0.989 | N | 0.423 | 0.364 | 0.292787519742 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.14E-06 | 0 |
| N/H | 5911 |
Ig-42 |
89 | rs781725187 |
0.0863 | -0.731 | 0.989 | N | 0.423 | 0.364 | 0.292787519742 | gnomAD-4.0.0 | 1.62191E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.91346E-06 | 0 | 0 |
| F/S | 6100 |
Ig-44 |
89 | rs761215282 |
0.1654 | -0.883 | 0.889 | N | 0.453 | 0.333 | 0.74728673918 | gnomAD-2.1.1 | 8.12E-06 | None | None | None | None | N | None | 6.49E-05 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| F/S | 6100 |
Ig-44 |
89 | rs761215282 |
0.1654 | -0.883 | 0.889 | N | 0.453 | 0.333 | 0.74728673918 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 9.41E-05 | 0 | 0 | 0 | 0 |
| F/S | 6100 |
Ig-44 |
89 | rs761215282 |
0.1654 | -0.883 | 0.889 | N | 0.453 | 0.333 | 0.74728673918 | gnomAD-4.0.0 | 6.20729E-06 | None | None | None | None | N | None | 2.67816E-05 | 0 | None | 0 | 0 | None | 3.1295E-05 | 0 | 0 | 6.60517E-05 | 0 |
| A/T | 6287 |
Ig-46 |
89 | None | 0.0643 | None | None | N | 0.107 | 0.082 | 0.0551355673512 | gnomAD-4.0.0 | 1.64281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.95342E-06 | 0 | 0 |
| R/I | 6473 |
Ig-48 |
89 | rs747454325 |
0.1993 | 0.26 | 0.006 | N | 0.171 | 0.322 | 0.494500980894 | gnomAD-2.1.1 | 1.8E-05 | None | None | None | None | N | None | 2.08229E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/I | 6473 |
Ig-48 |
89 | rs747454325 |
0.1993 | 0.26 | 0.006 | N | 0.171 | 0.322 | 0.494500980894 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20674E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/I | 6473 |
Ig-48 |
89 | rs747454325 |
0.1993 | 0.26 | 0.006 | N | 0.171 | 0.322 | 0.494500980894 | gnomAD-4.0.0 | 6.21323E-06 | None | None | None | None | N | None | 1.33647E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 6569 |
Ig-49 |
89 | rs1428304417 |
0.1099 | -0.465 | 0.472 | N | 0.384 | 0.247 | 0.241664281697 | gnomAD-2.1.1 | 4.61E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.44E-05 | None | 0 | 0 | 0 |
| T/A | 6569 |
Ig-49 |
89 | rs1428304417 |
0.1099 | -0.465 | 0.472 | N | 0.384 | 0.247 | 0.241664281697 | gnomAD-4.0.0 | 1.70176E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.61891E-05 | 0 |
| T/I | 6569 |
Ig-49 |
89 | None | 0.1788 | None | 0.792 | N | 0.393 | 0.212 | 0.431490205687 | gnomAD-4.0.0 | 1.70386E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.55493E-04 | 0 | 0 | 0 |
| L/F | 6662 |
Ig-50 |
89 | rs2079581150 |
0.0957 | None | 0.006 | N | 0.14 | 0.13 | 0.38342384377 | gnomAD-4.0.0 | 1.72006E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.64447E-05 | 0 |
| I/K | 6756 |
Ig-51 |
90 | None | 0.2015 | None | 0.351 | N | 0.437 | 0.238 | 0.677119849893 | gnomAD-4.0.0 | 1.81613E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.24699E-06 | 0 | 0 |
| I/M | 6756 |
Ig-51 |
90 | None | 0.0748 | None | 0.655 | D | 0.332 | 0.113 | 0.462461958149 | gnomAD-4.0.0 | 7.2273E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.34681E-07 | 0 | 0 |
| I/V | 6756 |
Ig-51 |
90 | rs767498851 |
0.0701 | -0.164 | 0.001 | N | 0.097 | 0.087 | 0.505765104075 | gnomAD-2.1.1 | 4.57E-06 | None | None | None | None | N | None | 0 | 3.68E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 6756 |
Ig-51 |
90 | rs767498851 |
0.0701 | -0.164 | 0.001 | N | 0.097 | 0.087 | 0.505765104075 | gnomAD-4.0.0 | 1.82085E-06 | None | None | None | None | N | None | 0 | 2.80096E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/A | 7036 |
Ig-54 |
89 | None | 0.111 | None | 0.09 | N | 0.439 | 0.215 | 0.308278614506 | gnomAD-4.0.0 | 6.85038E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00273E-07 | 0 | 0 |
| D/G | 7036 |
Ig-54 |
89 | rs767695386 |
0.1459 | -0.651 | 0.324 | N | 0.396 | 0.233 | 0.295623431141 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.67392E-04 |
| D/N | 7036 |
Ig-54 |
89 | rs72648962 |
0.0788 | -0.05 | 0.324 | N | 0.337 | 0.228 | None | gnomAD-2.1.1 | 5.53642E-03 | None | None | None | None | N | None | 5.34161E-02 | 3.0736E-03 | None | 5.45915E-03 | 0 | None | 1.6456E-04 | None | 0 | 4.86702E-04 | 3.11262E-03 |
| D/N | 7036 |
Ig-54 |
89 | rs72648962 |
0.0788 | -0.05 | 0.324 | N | 0.337 | 0.228 | None | gnomAD-3.1.2 | 1.57967E-02 | None | None | None | None | N | None | 5.31941E-02 | 7.39819E-03 | 0 | 6.34006E-03 | 0 | None | 0 | 9.49367E-03 | 3.52848E-04 | 2.06954E-04 | 1.7192E-02 |
| D/N | 7036 |
Ig-54 |
89 | rs72648962 |
0.0788 | -0.05 | 0.324 | N | 0.337 | 0.228 | None | 1000 genomes | 1.55751E-02 | None | None | None | None | N | None | 5.37E-02 | 8.6E-03 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| D/N | 7036 |
Ig-54 |
89 | rs72648962 |
0.0788 | -0.05 | 0.324 | N | 0.337 | 0.228 | None | gnomAD-4.0.0 | 3.23053E-03 | None | None | None | None | N | None | 5.26997E-02 | 4.61107E-03 | None | 6.8405E-03 | 0 | None | 0 | 3.47682E-03 | 3.53735E-04 | 1.65118E-04 | 5.25793E-03 |
| D/V | 7036 |
Ig-54 |
89 | rs767695386 |
0.121 | 0.279 | 0.324 | N | 0.509 | 0.285 | 0.467329424371 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 1.16598E-04 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| D/V | 7036 |
Ig-54 |
89 | rs767695386 |
0.121 | 0.279 | 0.324 | N | 0.509 | 0.285 | 0.467329424371 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/V | 7036 |
Ig-54 |
89 | rs767695386 |
0.121 | 0.279 | 0.324 | N | 0.509 | 0.285 | 0.467329424371 | gnomAD-4.0.0 | 1.17869E-05 | None | None | None | None | N | None | 0 | 8.35617E-05 | None | 0 | 2.23194E-05 | None | 0 | 0 | 1.10282E-05 | 0 | 0 |
| T/A | 7132 |
Ig-55 |
89 | rs1450786655 |
0.076 | None | None | N | 0.099 | 0.184 | 0.207176502487 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88018E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 7132 |
Ig-55 |
89 | rs1450786655 |
0.076 | None | None | N | 0.099 | 0.184 | 0.207176502487 | gnomAD-4.0.0 | 1.03036E-05 | None | None | None | None | N | None | 0 | 0 | None | 2.8866E-04 | 0 | None | 0 | 0 | 2.40963E-06 | 0 | 0 |
| F/L | 7225 |
Ig-56 |
89 | None | 0.6244 | None | 0.454 | N | 0.343 | 0.197 | 0.366085729538 | gnomAD-4.0.0 | 1.59947E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87256E-06 | 0 | 0 |
| F/S | 7225 |
Ig-56 |
89 | rs780534846 |
0.1434 | -1.853 | 0.051 | N | 0.318 | 0.219 | 0.570720304676 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.66E-05 | None | 0 | 8.95E-06 | 0 |
| F/S | 7225 |
Ig-56 |
89 | rs780534846 |
0.1434 | -1.853 | 0.051 | N | 0.318 | 0.219 | 0.570720304676 | gnomAD-4.0.0 | 2.74246E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80157E-06 | 2.3316E-05 | 0 |
| R/G | 7411 |
Ig-58 |
89 | rs780911294 |
0.1053 | -0.907 | 0.086 | N | 0.23 | 0.138 | 0.325533332567 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 2.96E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/G | 7411 |
Ig-58 |
89 | rs780911294 |
0.1053 | -0.907 | 0.086 | N | 0.23 | 0.138 | 0.325533332567 | gnomAD-4.0.0 | 1.60747E-06 | None | None | None | None | N | None | 0 | 2.31911E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 7603 |
Ig-60 |
89 | None | 0.0835 | None | 0.001 | D | 0.081 | 0.106 | 0.233785782151 | gnomAD-4.0.0 | 6.92636E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.06595E-07 | 0 | 0 |
| S/I | 7603 |
Ig-60 |
89 | rs777949804 |
0.095 | -0.05 | 0.213 | N | 0.519 | 0.252 | 0.41518383557 | gnomAD-2.1.1 | 4.19E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.18E-06 | 0 |
| S/I | 7603 |
Ig-60 |
89 | rs777949804 |
0.095 | -0.05 | 0.213 | N | 0.519 | 0.252 | 0.41518383557 | gnomAD-4.0.0 | 4.85413E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.44414E-06 | 1.22318E-05 | 0 |
| K/N | 7790 |
Ig-62 |
89 | rs752463765 |
0.2632 | 0.003 | 0.016 | D | 0.267 | 0.124 | 0.117506650769 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.32E-05 | None | 0 | 0 | 0 |
| K/N | 7790 |
Ig-62 |
89 | rs752463765 |
0.2632 | 0.003 | 0.016 | D | 0.267 | 0.124 | 0.117506650769 | gnomAD-4.0.0 | 1.59836E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.443E-05 | 0 |
| K/T | 7790 |
Ig-62 |
89 | rs756098759 |
0.0891 | -0.24 | 0.379 | N | 0.404 | 0.308 | 0.273938319068 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| K/T | 7790 |
Ig-62 |
89 | rs756098759 |
0.0891 | -0.24 | 0.379 | N | 0.404 | 0.308 | 0.273938319068 | gnomAD-4.0.0 | 1.59754E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86891E-06 | 0 | 0 |
| T/I | 7884 |
Ig-63 |
90 | rs1180482059 |
0.1906 | -0.397 | 0.193 | N | 0.409 | 0.196 | 0.412064437402 | gnomAD-2.1.1 | 4.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.38E-05 | None | 0 | 0 | 0 |
| T/I | 7884 |
Ig-63 |
90 | rs1180482059 |
0.1906 | -0.397 | 0.193 | N | 0.409 | 0.196 | 0.412064437402 | gnomAD-4.0.0 | 2.74767E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02053E-07 | 3.51725E-05 | 0 |
| H/Q | 7977 |
Ig-64 |
89 | rs1340162231 |
0.1238 | None | 0.68 | N | 0.354 | 0.266 | 0.139678290688 | gnomAD-4.0.0 | 1.37764E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.81001E-06 | 0 | 0 |
| H/R | 7977 |
Ig-64 |
89 | rs1357770681 |
0.0966 | None | 0.68 | N | 0.342 | 0.242 | 0.315314060047 | gnomAD-4.0.0 | 2.06622E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.71478E-06 | 0 | 0 |
| H/Y | 7977 |
Ig-64 |
89 | None | 0.0895 | None | 0.006 | N | 0.079 | 0.259 | 0.286081765059 | gnomAD-4.0.0 | 1.61498E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.91189E-06 | 0 | 0 |
| T/N | 8073 |
Ig-65 |
89 | None | 0.092 | None | 0.175 | N | 0.305 | 0.106 | 0.345405024496 | gnomAD-4.0.0 | 1.32035E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-05 | 0 | 3.66327E-05 |
| F/L | 8166 |
Ig-66 |
89 | None | 0.6259 | None | None | N | 0.069 | 0.17 | 0.26547132957 | gnomAD-4.0.0 | 1.59266E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86121E-06 | 0 | 0 |
| F/S | 8166 |
Ig-66 |
89 | None | 0.1648 | None | 0.021 | N | 0.219 | 0.182 | 0.592052101994 | gnomAD-4.0.0 | 6.84458E-07 | None | None | None | None | N | None | 2.98882E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 8259 |
Ig-67 |
89 | None | 0.2117 | None | 0.457 | N | 0.473 | 0.307 | 0.521070178209 | gnomAD-4.0.0 | 6.84578E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99881E-07 | 0 | 0 |
| S/Y | 8259 |
Ig-67 |
89 | rs868000266 |
0.1676 | None | 0.001 | N | 0.404 | 0.309 | 0.481543764896 | gnomAD-4.0.0 | 8.89951E-06 | None | None | None | None | N | None | 2.99168E-05 | 0 | None | 0 | 0 | None | 0 | 2.08551E-03 | 0 | 0 | 0 |
| V/L | 8352 |
Ig-68 |
89 | rs750897859 |
0.125 | -0.232 | 0.001 | N | 0.257 | 0.194 | 0.358340041657 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| V/L | 8352 |
Ig-68 |
89 | rs750897859 |
0.125 | -0.232 | 0.001 | N | 0.257 | 0.194 | 0.358340041657 | gnomAD-4.0.0 | 9.58653E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.72491E-05 | 0 | 0 |
| I/T | 8448 |
Ig-69 |
89 | rs2077674998 |
0.1639 | None | None | N | 0.109 | 0.069 | 0.224531998449 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 8448 |
Ig-69 |
89 | rs2077674998 |
0.1639 | None | None | N | 0.109 | 0.069 | 0.224531998449 | gnomAD-4.0.0 | 6.57108E-06 | None | None | None | None | N | None | 2.41185E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 8544 |
Ig-70 |
89 | rs2077603060 |
0.0726 | None | 0.009 | N | 0.189 | 0.202 | 0.178374595973 | gnomAD-4.0.0 | 1.3717E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80309E-06 | 0 | 0 |
| G/D | 8544 |
Ig-70 |
89 | None | 0.186 | None | 0.861 | N | 0.631 | 0.257 | 0.312306559268 | gnomAD-4.0.0 | 2.7434E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60617E-06 | 0 | 0 |
| K/N | 8638 |
Ig-71 |
90 | None | 0.4627 | None | 0.447 | N | 0.275 | 0.059 | 0.197625483188 | gnomAD-4.0.0 | 1.59765E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87396E-06 | 0 | 0 |
| A/P | 8731 |
Ig-72 |
89 | rs1013992395 |
0.2761 | None | 0.232 | N | 0.315 | 0.083 | 0.202086224978 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/P | 8731 |
Ig-72 |
89 | rs1013992395 |
0.2761 | None | 0.232 | N | 0.315 | 0.083 | 0.202086224978 | gnomAD-4.0.0 | 6.57315E-06 | None | None | None | None | N | None | 0 | 6.54793E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/S | 8731 |
Ig-72 |
89 | None | 0.0703 | None | 0.013 | N | 0.208 | 0.055 | 0.0986583533028 | gnomAD-4.0.0 | 1.37455E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80484E-06 | 0 | 0 |
| A/T | 8731 |
Ig-72 |
89 | rs1013992395 |
0.0558 | -0.556 | None | N | 0.057 | 0.085 | 0.0920862733494 | gnomAD-2.1.1 | 8.23E-06 | None | None | None | None | N | None | 0 | 5.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 8731 |
Ig-72 |
89 | rs1013992395 |
0.0558 | -0.556 | None | N | 0.057 | 0.085 | 0.0920862733494 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 8731 |
Ig-72 |
89 | rs1013992395 |
0.0558 | -0.556 | None | N | 0.057 | 0.085 | 0.0920862733494 | gnomAD-4.0.0 | 9.95547E-06 | None | None | None | None | N | None | 0 | 8.36204E-05 | None | 0 | 0 | None | 0 | 0 | 7.65211E-06 | 0 | 3.21554E-05 |
| A/V | 8731 |
Ig-72 |
89 | rs1479171654 |
0.0692 | 0.08 | None | N | 0.065 | 0.08 | 0.171388866994 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.1E-06 | 0 |
| A/V | 8731 |
Ig-72 |
89 | rs1479171654 |
0.0692 | 0.08 | None | N | 0.065 | 0.08 | 0.171388866994 | gnomAD-4.0.0 | 4.82279E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77608E-05 | None | 0 | 0 | 5.77624E-06 | 0 | 0 |
| S/F | 8825 |
Ig-73 |
90 | rs2077128629 |
0.1194 | None | 0.017 | N | 0.417 | 0.297 | 0.569067374492 | gnomAD-4.0.0 | 1.59566E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.775E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Q/K | 8918 |
Ig-74 |
89 | None | 0.0801 | None | 0.002 | N | 0.038 | 0.148 | 0.166414681773 | gnomAD-4.0.0 | 3.4231E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.4996E-06 | 0 | 0 |
| Q/R | 8918 |
Ig-74 |
89 | rs760040495 |
0.0782 | 0.337 | 0.061 | N | 0.213 | 0.113 | 0.158396225186 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11445E-04 | None | 0 | None | 0 | 0 | 0 |
| Q/R | 8918 |
Ig-74 |
89 | rs760040495 |
0.0782 | 0.337 | 0.061 | N | 0.213 | 0.113 | 0.158396225186 | gnomAD-4.0.0 | 3.42336E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.56201E-05 | None | 0 | 0 | 1.79993E-06 | 0 | 0 |
| Y/C | 9107 |
Ig-76 |
89 | None | 0.1293 | None | 0.828 | N | 0.339 | 0.196 | 0.515430650102 | gnomAD-4.0.0 | 1.59375E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86459E-06 | 0 | 0 |
| L/F | 9200 |
Ig-77 |
89 | None | 0.0651 | None | 0.966 | N | 0.329 | 0.148 | 0.321951552304 | gnomAD-4.0.0 | 1.5923E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43353E-05 | 0 |
| L/P | 9200 |
Ig-77 |
89 | rs776598104 |
0.689 | None | 0.966 | N | 0.368 | 0.315 | 0.495506531988 | gnomAD-4.0.0 | 1.36927E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80009E-06 | 0 | 0 |
| L/R | 9200 |
Ig-77 |
89 | rs776598104 |
0.0932 | 0.177 | 0.876 | N | 0.346 | 0.272 | 0.430126000877 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.55E-05 | None | 0 | 0 | 0 |
| L/R | 9200 |
Ig-77 |
89 | rs776598104 |
0.0932 | 0.177 | 0.876 | N | 0.346 | 0.272 | 0.430126000877 | gnomAD-4.0.0 | 2.0539E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73491E-04 | 0 | 2.32024E-05 | 0 |
| T/I | 9293 |
Ig-78 |
89 | None | 0.1098 | None | 0.497 | N | 0.476 | 0.289 | 0.442775082573 | gnomAD-4.0.0 | 6.92585E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.20937E-05 | 0 |
| T/N | 9293 |
Ig-78 |
89 | rs2076722601 |
0.1043 | None | 0.004 | N | 0.23 | 0.133 | 0.323615622048 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 9293 |
Ig-78 |
89 | rs2076722601 |
0.1043 | None | 0.004 | N | 0.23 | 0.133 | 0.323615622048 | gnomAD-4.0.0 | 6.57056E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46985E-05 | 0 | 0 |
| T/S | 9293 |
Ig-78 |
89 | None | 0.0986 | None | None | N | 0.117 | 0.117 | 0.191931220699 | gnomAD-4.0.0 | 6.92584E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.07222E-07 | 0 | 0 |
| I/L | 9389 |
Ig-79 |
89 | rs1577825049 |
0.1011 | None | 0.047 | None | 0.151 | 0.076 | 0.338110398507 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 9389 |
Ig-79 |
89 | rs1577825049 |
0.1011 | None | 0.047 | None | 0.151 | 0.076 | 0.338110398507 | gnomAD-4.0.0 | 6.56961E-06 | None | None | None | None | N | None | 2.41161E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 9389 |
Ig-79 |
89 | rs1577825049 |
0.0958 | None | 0.001 | None | 0.118 | 0.047 | 0.250039746154 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 9389 |
Ig-79 |
89 | rs1577825049 |
0.0958 | None | 0.001 | None | 0.118 | 0.047 | 0.250039746154 | gnomAD-4.0.0 | 4.42798E-06 | None | None | None | None | N | None | 1.36418E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.14991E-06 | 0 | 0 |
| V/F | 9582 |
Ig-81 |
90 | rs537805395 |
0.204 | -0.752 | 0.828 | None | 0.361 | 0.22 | 0.458644561121 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92456E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/F | 9582 |
Ig-81 |
90 | rs537805395 |
0.204 | -0.752 | 0.828 | None | 0.361 | 0.22 | 0.458644561121 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| V/F | 9582 |
Ig-81 |
90 | rs537805395 |
0.204 | -0.752 | 0.828 | None | 0.361 | 0.22 | 0.458644561121 | gnomAD-4.0.0 | 6.56806E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 9582 |
Ig-81 |
90 | rs537805395 |
0.0809 | -0.165 | 0.009 | None | 0.146 | 0.102 | 0.156986980423 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 2.69E-05 | 0 |
| V/I | 9582 |
Ig-81 |
90 | rs537805395 |
0.0809 | -0.165 | 0.009 | None | 0.146 | 0.102 | 0.156986980423 | gnomAD-4.0.0 | 1.58394E-05 | None | None | None | None | N | None | 3.00391E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.72111E-05 | 3.49138E-05 | 0 |
| T/A | 9678 |
Ig-82 |
89 | None | 0.1 | None | 0.001 | None | 0.204 | 0.12 | 0.163833314356 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| Q/R | 9787 |
Ig-83 |
90 | None | 0.2729 | None | 0.642 | None | 0.185 | 0.258 | 0.166414681773 | gnomAD-4.0.0 | 1.59115E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| T/I | 9985 |
Ig-84 |
86 | rs1339300021 |
0.3541 | None | 0.379 | None | 0.514 | 0.328 | 0.326074293725 | gnomAD-4.0.0 | 4.82177E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.75377E-04 | 3.61473E-06 | 0 | 3.33901E-05 |
| T/S | 9985 |
Ig-84 |
86 | None | 0.3232 | None | 0.016 | None | 0.345 | 0.067 | 0.104622674875 | gnomAD-4.0.0 | 6.88825E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.03684E-07 | 0 | 0 |
| V/A | 13774 |
Ig-87 |
91 | rs1423291544 |
0.2131 | None | 0.052 | N | 0.389 | 0.228 | 0.579595062312 | gnomAD-4.0.0 | 6.89187E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0409E-07 | 0 | 0 |
| V/D | 13774 |
Ig-87 |
91 | rs1423291544 |
0.5119 | None | 0.484 | N | 0.628 | 0.415 | 0.771676275692 | gnomAD-4.0.0 | 6.89187E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.67068E-05 |
| V/F | 13774 |
Ig-87 |
91 | rs768582792 |
0.1545 | None | 0.317 | N | 0.438 | 0.112 | 0.589843679045 | gnomAD-4.0.0 | 1.37868E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.08156E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 13774 |
Ig-87 |
91 | rs768582792 |
0.1226 | None | 0.004 | N | 0.282 | 0.092 | 0.32471235697 | gnomAD-4.0.0 | 2.06801E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.71266E-06 | 0 | 0 |
| K/E | 13867 |
Ig-88 |
88 | rs1406730478 |
0.4724 | 0.464 | 0.41 | N | 0.525 | 0.218 | 0.151104730317 | gnomAD-2.1.1 | 4.2E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.26E-06 | 0 |
| K/E | 13867 |
Ig-88 |
88 | rs1406730478 |
0.4724 | 0.464 | 0.41 | N | 0.525 | 0.218 | 0.151104730317 | gnomAD-4.0.0 | 2.0779E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.7244E-06 | 0 | 0 |
| K/I | 13867 |
Ig-88 |
88 | rs2060384934 |
0.772 | None | 0.908 | N | 0.706 | 0.279 | 0.322786055943 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/I | 13867 |
Ig-88 |
88 | rs2060384934 |
0.772 | None | 0.908 | N | 0.706 | 0.279 | 0.322786055943 | gnomAD-4.0.0 | 6.57609E-06 | None | None | None | None | N | None | 2.41359E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 14136 |
Ig-91 |
83 | None | 0.2321 | None | 0.473 | N | 0.349 | 0.154 | 0.583333579207 | gnomAD-4.0.0 | 1.61712E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87712E-06 | 0 | 0 |
| T/A | 14313 |
Ig-93 |
83 | rs752143463 |
0.0822 | -0.7 | None | N | 0.085 | 0.107 | 0.0666544352282 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/A | 14313 |
Ig-93 |
83 | rs752143463 |
0.0822 | -0.7 | None | N | 0.085 | 0.107 | 0.0666544352282 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 14313 |
Ig-93 |
83 | rs752143463 |
0.0822 | -0.7 | None | N | 0.085 | 0.107 | 0.0666544352282 | gnomAD-4.0.0 | 3.84533E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.18284E-06 | 0 | 0 |
| T/S | 14313 |
Ig-93 |
83 | None | 0.0963 | None | 0.001 | N | 0.129 | 0.079 | 0.0138822411134 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 14580 |
Ig-96 |
84 | rs1381530830 |
0.1586 | -0.828 | 0.958 | D | 0.499 | 0.667 | 0.4744847356 | gnomAD-2.1.1 | 4.34E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.52E-06 | 0 |
| T/I | 14580 |
Ig-96 |
84 | None | 0.1838 | None | 0.142 | D | 0.254 | 0.402 | 0.478299402934 | gnomAD-4.0.0 | 1.64042E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.93719E-06 | 0 | 0 |
| T/S | 14580 |
Ig-96 |
84 | None | 0.2121 | None | 0.979 | D | 0.506 | 0.593 | 0.381239546501 | gnomAD-4.0.0 | 1.64042E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.93719E-06 | 0 | 0 |
| R/G | 14758 |
Ig-98 |
84 | None | 0.5303 | None | 0.753 | N | 0.562 | 0.205 | 0.220303561663 | gnomAD-4.0.0 | 1.36911E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79958E-06 | 0 | 0 |
| R/P | 14758 |
Ig-98 |
84 | None | 0.9589 | None | 0.956 | N | 0.777 | 0.245 | 0.257786959452 | gnomAD-4.0.0 | 1.36908E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79957E-06 | 0 | 0 |
| R/Q | 14758 |
Ig-98 |
84 | rs770389312 |
0.1384 | 0.052 | 0.922 | N | 0.536 | 0.145 | 0.119812018005 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 5.67E-05 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 3.91E-05 | 1.40331E-04 |
| R/Q | 14758 |
Ig-98 |
84 | rs770389312 |
0.1384 | 0.052 | 0.922 | N | 0.536 | 0.145 | 0.119812018005 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 2.88184E-04 | 0 | None | 0 | 0 | 8.82E-05 | 0 | 0 |
| R/Q | 14758 |
Ig-98 |
84 | rs770389312 |
0.1384 | 0.052 | 0.922 | N | 0.536 | 0.145 | 0.119812018005 | gnomAD-4.0.0 | 5.0841E-05 | None | None | None | None | N | None | 0 | 6.67312E-05 | None | 6.76178E-05 | 0 | None | 0 | 0 | 5.68099E-05 | 6.59413E-05 | 4.80646E-05 |
| L/F | 15385 |
Ig-105 |
84 | rs2058085346 |
0.2497 | None | 0.982 | N | 0.407 | 0.214 | 0.553063759574 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 15385 |
Ig-105 |
84 | rs2058085346 |
0.2497 | None | 0.982 | N | 0.407 | 0.214 | 0.553063759574 | gnomAD-4.0.0 | 6.58285E-06 | None | None | None | None | N | None | 2.41511E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/R | 15385 |
Ig-105 |
84 | None | 0.2776 | None | 0.997 | N | 0.542 | 0.433 | 0.66790570697 | gnomAD-4.0.0 | 1.59966E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87237E-06 | 0 | 0 |
| N/I | 16051 |
Ig-109 |
84 | None | 0.3281 | None | 0.82 | D | 0.644 | 0.314 | 0.507213507908 | gnomAD-4.0.0 | 2.05405E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.48036E-05 | 0 |
| N/S | 16051 |
Ig-109 |
84 | rs534426018 |
0.1229 | -0.43 | 0.034 | D | 0.293 | 0.161 | 0.187945064343 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 1.67654E-04 | None | 0 | None | 0 | 2.68E-05 | 0 |
| N/S | 16051 |
Ig-109 |
84 | rs534426018 |
0.1229 | -0.43 | 0.034 | D | 0.293 | 0.161 | 0.187945064343 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 16051 |
Ig-109 |
84 | rs534426018 |
0.1229 | -0.43 | 0.034 | D | 0.293 | 0.161 | 0.187945064343 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| N/S | 16051 |
Ig-109 |
84 | rs534426018 |
0.1229 | -0.43 | 0.034 | D | 0.293 | 0.161 | 0.187945064343 | gnomAD-4.0.0 | 1.48831E-05 | None | None | None | None | N | None | 5.34045E-05 | 0 | None | 0 | 2.23414E-04 | None | 0 | 1.65344E-04 | 5.08841E-06 | 2.19727E-05 | 1.60241E-05 |
| K/Q | 17043 |
Ig-111 |
89 | rs794729269 |
0.1994 | None | 0.975 | N | 0.694 | 0.358 | None | gnomAD-4.0.0 | 4.10937E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.40056E-06 | 0 | 0 |
| K/R | 17043 |
Ig-111 |
89 | rs758910983 |
0.1117 | -0.006 | 0.787 | N | 0.589 | 0.273 | 0.407357902709 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.61E-05 | None | 0 | 0 | 0 |
| K/R | 17043 |
Ig-111 |
89 | rs758910983 |
0.1117 | -0.006 | 0.787 | N | 0.589 | 0.273 | 0.407357902709 | gnomAD-4.0.0 | 2.73967E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80024E-06 | 2.32683E-05 | 0 |
| E/G | 17760 |
Ig-113 |
84 | rs2055156080 |
0.6995 | None | 0.994 | N | 0.604 | 0.535 | 0.549078225428 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 17760 |
Ig-113 |
84 | None | 0.4113 | None | 0.989 | N | 0.516 | 0.355 | 0.273503213844 | gnomAD-4.0.0 | 1.5927E-06 | None | None | None | None | N | None | 5.66829E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 18061 |
Ig-114 |
94 | rs757026449 |
0.2105 | -1.092 | 0.993 | N | 0.331 | 0.202 | 0.292423486923 | gnomAD-2.1.1 | 8.49E-06 | None | None | None | None | N | None | 0 | 5.99E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/D | 18061 |
Ig-114 |
94 | rs757026449 |
0.2105 | -1.092 | 0.993 | N | 0.331 | 0.202 | 0.292423486923 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 18061 |
Ig-114 |
94 | rs757026449 |
0.2105 | -1.092 | 0.993 | N | 0.331 | 0.202 | 0.292423486923 | gnomAD-4.0.0 | 3.93583E-06 | None | None | None | None | N | None | 0 | 5.19409E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 18061 |
Ig-114 |
94 | None | 0.5447 | None | 0.979 | N | 0.322 | 0.338 | 0.393471546983 | gnomAD-4.0.0 | 1.63943E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94473E-06 | 0 | 0 |
| D/N | 19179 |
Ig-117 |
85 | rs1383899808 |
0.4045 | None | 0.989 | N | 0.551 | 0.337 | 0.342631996419 | gnomAD-4.0.0 | 6.85537E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00314E-07 | 0 | 0 |
| N/H | 19475 |
Ig-118 |
85 | None | 0.0991 | None | 0.56 | N | 0.409 | 0.157 | 0.287603790349 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/S | 19475 |
Ig-118 |
85 | rs755738851 |
0.0758 | 0.015 | 0.001 | N | 0.09 | 0.07 | 0.200317383148 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 8.26E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 2.81215E-04 |
| N/S | 19475 |
Ig-118 |
85 | rs755738851 |
0.0758 | 0.015 | 0.001 | N | 0.09 | 0.07 | 0.200317383148 | gnomAD-4.0.0 | 4.10627E-06 | None | None | None | None | N | None | 1.19567E-04 | 0 | None | 0 | 0 | None | 0 | 3.47222E-04 | 0 | 0 | 0 |
| L/F | 19873 |
Ig-119 |
84 | None | 0.146 | None | 0.003 | N | 0.275 | 0.177 | 0.62963637804 | gnomAD-4.0.0 | 6.84901E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99784E-07 | 0 | 0 |
| L/P | 19873 |
Ig-119 |
84 | rs727503589 |
0.9344 | -0.439 | 0.912 | N | 0.588 | 0.48 | 0.86720306763 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.68E-05 | 0 |
| L/P | 19873 |
Ig-119 |
84 | rs727503589 |
0.9344 | -0.439 | 0.912 | N | 0.588 | 0.48 | 0.86720306763 | gnomAD-4.0.0 | 8.21947E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.07973E-05 | 0 | 0 |
| L/V | 19873 |
Ig-119 |
84 | rs1185370817 |
0.0602 | -0.299 | 0.001 | N | 0.127 | 0.057 | 0.50343701615 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.31E-05 | None | 0 | 0 | 0 |
| L/V | 19873 |
Ig-119 |
84 | rs1185370817 |
0.0602 | -0.299 | 0.001 | N | 0.127 | 0.057 | 0.50343701615 | gnomAD-4.0.0 | 6.84901E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65832E-05 |
| T/I | 20167 |
Ig-120 |
88 | None | 0.1869 | None | 1.0 | D | 0.816 | 0.455 | 0.642232531769 | gnomAD-4.0.0 | 6.84356E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99622E-07 | 0 | 0 |
| T/P | 20167 |
Ig-120 |
88 | None | 0.8135 | None | 1.0 | D | 0.798 | 0.557 | 0.66854072215 | gnomAD-4.0.0 | 1.59204E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85977E-06 | 0 | 0 |
| T/S | 20167 |
Ig-120 |
88 | rs2050127510 |
0.1667 | None | 0.999 | D | 0.577 | 0.421 | 0.508696012846 | gnomAD-4.0.0 | 1.36871E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79924E-06 | 0 | 0 |
| N/K | 20565 |
Ig-121 |
87 | None | 0.7033 | None | 1.0 | N | 0.741 | 0.343 | 0.24896430686 | gnomAD-4.0.0 | 6.84484E-07 | None | None | None | None | I | None | 2.99061E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 20860 |
Ig-122 |
92 | rs1405326036 |
0.0968 | None | 0.008 | N | 0.085 | 0.122 | 0.229264304666 | gnomAD-4.0.0 | 3.42224E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52653E-05 | None | 0 | 0 | 1.79913E-06 | 0 | 3.314E-05 |
| R/G | 21262 |
Ig-123 |
86 | None | 0.5887 | None | 0.117 | N | 0.473 | 0.307 | 0.43923137753 | gnomAD-4.0.0 | 1.60277E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87829E-06 | 0 | 0 |
| R/T | 21262 |
Ig-123 |
86 | rs1342165359 |
0.3443 | -0.254 | 0.117 | N | 0.448 | 0.145 | 0.331365685468 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | I | None | 0 | 2.95E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/T | 21262 |
Ig-123 |
86 | rs1342165359 |
0.3443 | -0.254 | 0.117 | N | 0.448 | 0.145 | 0.331365685468 | gnomAD-4.0.0 | 1.60321E-06 | None | None | None | None | I | None | 0 | 2.31471E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 21555 |
Ig-124 |
87 | rs756320940 |
0.1732 | -0.905 | 0.027 | N | 0.311 | 0.098 | 0.343560092441 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.03E-06 | 0 |
| V/A | 21555 |
Ig-124 |
87 | rs756320940 |
0.1732 | -0.905 | 0.027 | N | 0.311 | 0.098 | 0.343560092441 | gnomAD-4.0.0 | 1.37635E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80548E-06 | 0 | 0 |
| V/L | 21555 |
Ig-124 |
87 | None | 0.1337 | None | 0.004 | N | 0.245 | 0.125 | 0.275215494804 | gnomAD-4.0.0 | 1.61303E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89198E-06 | 0 | 0 |
| K/E | 21952 |
Ig-125 |
87 | rs2048118319 |
0.4118 | None | 0.811 | N | 0.601 | 0.276 | 0.233785782151 | gnomAD-4.0.0 | 5.55821E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.77301E-05 | None | 0 | 0 | 3.27255E-06 | 0 | 0 |
| K/I | 21952 |
Ig-125 |
87 | rs371740766 |
0.4244 | None | 0.968 | N | 0.74 | 0.443 | None | gnomAD-4.0.0 | 1.45816E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.87469E-06 | 0 | 0 |
| K/R | 21952 |
Ig-125 |
87 | None | 0.1008 | None | 0.811 | N | 0.555 | 0.157 | 0.367042808489 | gnomAD-4.0.0 | 7.29079E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.37346E-07 | 0 | 0 |
| K/Q | 22350 |
Ig-126 |
86 | rs1370592733 |
0.548 | 0.005 | 0.957 | N | 0.643 | 0.354 | 0.33340067248 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| K/Q | 22350 |
Ig-126 |
86 | rs1370592733 |
0.548 | 0.005 | 0.957 | N | 0.643 | 0.354 | 0.33340067248 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| K/Q | 22350 |
Ig-126 |
86 | rs1370592733 |
0.548 | 0.005 | 0.957 | N | 0.643 | 0.354 | 0.33340067248 | gnomAD-4.0.0 | 3.72098E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08772E-06 | 0 | 0 |
| T/A | 23036 |
Ig-128 |
87 | None | 0.0894 | None | 0.027 | D | 0.406 | 0.165 | 0.286848849266 | gnomAD-4.0.0 | 3.18532E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71997E-06 | 0 | 0 |
| T/I | 23036 |
Ig-128 |
87 | rs1056452429 |
0.1303 | 0.095 | 0.317 | N | 0.443 | 0.216 | 0.40146981186 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 23036 |
Ig-128 |
87 | rs1056452429 |
0.1303 | 0.095 | 0.317 | N | 0.443 | 0.216 | 0.40146981186 | gnomAD-4.0.0 | 1.36897E-06 | None | None | None | None | N | None | 0 | 2.23774E-05 | None | 0 | 0 | None | 0 | 0 | 8.99649E-07 | 0 | 0 |
| R/T | 24515 |
Ig-132 |
85 | rs1470812776 |
0.7333 | None | 0.892 | N | 0.617 | 0.328 | 0.492749560936 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/T | 24515 |
Ig-132 |
85 | rs1470812776 |
0.7333 | None | 0.892 | N | 0.617 | 0.328 | 0.492749560936 | gnomAD-4.0.0 | 1.85954E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54322E-06 | 0 | 0 |
| I/T | 24804 |
Ig-133 |
89 | None | 0.1392 | None | 0.549 | N | 0.345 | 0.267 | 0.723580609706 | gnomAD-4.0.0 | 1.36863E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79917E-06 | 0 | 0 |
| I/V | 24804 |
Ig-133 |
89 | rs544547448 |
0.0638 | -0.493 | 0.001 | N | 0.103 | 0.065 | 0.489658423131 | gnomAD-2.1.1 | 7.16E-06 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 24804 |
Ig-133 |
89 | rs544547448 |
0.0638 | -0.493 | 0.001 | N | 0.103 | 0.065 | 0.489658423131 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 24804 |
Ig-133 |
89 | rs544547448 |
0.0638 | -0.493 | 0.001 | N | 0.103 | 0.065 | 0.489658423131 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/V | 24804 |
Ig-133 |
89 | rs544547448 |
0.0638 | -0.493 | 0.001 | N | 0.103 | 0.065 | 0.489658423131 | gnomAD-4.0.0 | 6.56935E-06 | None | None | None | None | N | None | 2.40547E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/M | 25200 |
Ig-134 |
90 | None | 0.2829 | None | 1.0 | N | 0.661 | 0.604 | 0.473695954338 | gnomAD-4.0.0 | 1.36882E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79921E-06 | 0 | 0 |
| K/Q | 26679 |
Ig-138 |
86 | None | 0.4714 | None | 1.0 | D | 0.732 | 0.496 | 0.363944505237 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| K/T | 26679 |
Ig-138 |
86 | rs776990508 |
0.6991 | -0.024 | 1.0 | N | 0.741 | 0.559 | 0.434934176536 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| K/T | 26679 |
Ig-138 |
86 | rs776990508 |
0.6991 | -0.024 | 1.0 | N | 0.741 | 0.559 | 0.434934176536 | gnomAD-4.0.0 | 3.42129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49767E-06 | 0 | 0 |
| I/N | 26968 |
Ig-139 |
89 | rs369539943 |
0.4421 | -0.252 | 0.942 | N | 0.627 | 0.424 | 0.823678856618 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| I/N | 26968 |
Ig-139 |
89 | rs369539943 |
0.4421 | -0.252 | 0.942 | N | 0.627 | 0.424 | 0.823678856618 | gnomAD-4.0.0 | 1.36856E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79905E-06 | 0 | 0 |
| I/T | 26968 |
Ig-139 |
89 | rs369539943 |
0.1689 | -0.556 | 0.014 | N | 0.371 | 0.317 | None | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| I/T | 26968 |
Ig-139 |
89 | rs369539943 |
0.1689 | -0.556 | 0.014 | N | 0.371 | 0.317 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93424E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/T | 26968 |
Ig-139 |
89 | rs369539943 |
0.1689 | -0.556 | 0.014 | N | 0.371 | 0.317 | None | gnomAD-4.0.0 | 4.95829E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23065E-05 | None | 0 | 0 | 5.93371E-06 | 0 | 0 |
| K/R | 27365 |
Ig-140 |
88 | None | 0.0895 | None | 0.999 | N | 0.591 | 0.319 | 0.486567385682 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| R/T | 27762 |
Ig-141 |
87 | rs562523414 |
0.816 | -0.297 | 0.822 | N | 0.611 | 0.286 | 0.436348499334 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| R/T | 27762 |
Ig-141 |
87 | rs562523414 |
0.816 | -0.297 | 0.822 | N | 0.611 | 0.286 | 0.436348499334 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| R/T | 27762 |
Ig-141 |
87 | rs562523414 |
0.816 | -0.297 | 0.822 | N | 0.611 | 0.286 | 0.436348499334 | gnomAD-4.0.0 | 4.0596E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.87917E-04 | 0 |
| I/T | 28051 |
Ig-142 |
89 | rs748178006 |
0.12 | -0.799 | 0.549 | N | 0.313 | 0.243 | 0.754759076288 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| I/T | 28051 |
Ig-142 |
89 | rs748178006 |
0.12 | -0.799 | 0.549 | N | 0.313 | 0.243 | 0.754759076288 | gnomAD-4.0.0 | 6.15983E-06 | None | None | None | None | N | None | 2.98954E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19708E-06 | 0 | 0 |
| K/E | 28446 |
Ig-143 |
89 | None | 0.318 | None | 0.822 | N | 0.553 | 0.264 | 0.365317461125 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 28841 |
Ig-144 |
87 | rs879227926 |
0.8957 | None | 0.998 | D | 0.629 | 0.338 | 0.218845423259 | gnomAD-4.0.0 | 1.59126E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.76735E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 29133 |
Ig-145 |
89 | rs1396011615 |
0.0608 | -0.146 | None | N | 0.123 | 0.074 | 0.12205267543 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/I | 29133 |
Ig-145 |
89 | rs1396011615 |
0.0608 | -0.146 | None | N | 0.123 | 0.074 | 0.12205267543 | gnomAD-4.0.0 | 6.84463E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| Q/H | 29529 |
Ig-146 |
86 | None | 0.2609 | None | 0.996 | N | 0.383 | 0.341 | 0.27132560031 | gnomAD-4.0.0 | 6.84184E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99428E-07 | 0 | 0 |
| Q/R | 29529 |
Ig-146 |
86 | None | 0.1312 | None | 0.986 | N | 0.32 | 0.294 | 0.232513804876 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/E | 31012 |
Ig-150 |
86 | None | 0.8983 | None | 0.999 | N | 0.625 | 0.493 | 0.354610295913 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88232E-05 | 0 | 0 | 0 | 0 |
| K/I | 31012 |
Ig-150 |
86 | rs1698136089 |
0.9098 | None | 1.0 | N | 0.814 | 0.611 | 0.614323175037 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/I | 31012 |
Ig-150 |
86 | rs1698136089 |
0.9098 | None | 1.0 | N | 0.814 | 0.611 | 0.614323175037 | gnomAD-4.0.0 | 6.57212E-06 | None | None | None | None | N | None | 0 | 6.55394E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 31012 |
Ig-150 |
86 | None | 0.945 | None | 1.0 | D | 0.765 | 0.329 | 0.235038932564 | gnomAD-4.0.0 | 1.59112E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85806E-06 | 0 | 0 |
| V/M | 31304 |
Ig-151 |
87 | rs879165673 |
0.1178 | -0.251 | 0.627 | N | 0.412 | 0.102 | 0.68170140072 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| V/M | 31304 |
Ig-151 |
87 | rs879165673 |
0.1178 | -0.251 | 0.627 | N | 0.412 | 0.102 | 0.68170140072 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/M | 31304 |
Ig-151 |
87 | rs879165673 |
0.1178 | -0.251 | 0.627 | N | 0.412 | 0.102 | 0.68170140072 | gnomAD-4.0.0 | 2.02989E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40984E-06 | 0 | 0 |
| K/R | 31704 |
Ig-152 |
84 | rs754379972 |
0.093 | 0.092 | 0.999 | N | 0.618 | 0.355 | 0.538468847496 | gnomAD-2.1.1 | 8.13E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 6.67E-05 | None | 0 | 0 | 0 |
| K/R | 31704 |
Ig-152 |
84 | rs754379972 |
0.093 | 0.092 | 0.999 | N | 0.618 | 0.355 | 0.538468847496 | gnomAD-4.0.0 | 4.81439E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.33438E-05 | 0 |
| I/F | 32395 |
Ig-154 |
89 | None | 0.3226 | None | 0.942 | N | 0.553 | 0.307 | 0.663397737457 | gnomAD-4.0.0 | 6.855E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01374E-07 | 0 | 0 |
| I/T | 32395 |
Ig-154 |
89 | None | 0.3689 | None | 0.822 | N | 0.571 | 0.311 | 0.743037970187 | gnomAD-4.0.0 | 2.7418E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.7039E-06 | 0 | 1.6597E-05 |
| I/V | 32395 |
Ig-154 |
89 | None | 0.0857 | None | 0.006 | N | 0.207 | 0.051 | 0.524271286562 | gnomAD-4.0.0 | 6.855E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01374E-07 | 0 | 0 |
| R/S | 32791 |
Ig-155 |
84 | None | 0.3824 | None | 0.062 | N | 0.431 | 0.093 | 0.250579442822 | gnomAD-4.0.0 | 6.84227E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65645E-05 |
| R/T | 32791 |
Ig-155 |
84 | None | 0.1612 | None | 0.117 | N | 0.444 | 0.08 | 0.254761474806 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/D | 33286 |
Ig-157 |
84 | rs1362585366 |
0.2873 | -1.366 | 0.979 | N | 0.51 | 0.268 | 0.439763647824 | gnomAD-2.1.1 | 5.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.05E-05 | 0 |
| E/K | 33286 |
Ig-157 |
84 | rs780655169 |
0.3231 | -0.915 | 0.999 | N | 0.659 | 0.33 | None | gnomAD-2.1.1 | 1.5E-05 | None | None | None | None | N | None | 6.95E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.08E-05 | 0 |
| E/K | 33286 |
Ig-157 |
84 | rs780655169 |
0.3231 | -0.915 | 0.999 | N | 0.659 | 0.33 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 33286 |
Ig-157 |
84 | rs780655169 |
0.3231 | -0.915 | 0.999 | N | 0.659 | 0.33 | None | gnomAD-4.0.0 | 7.75374E-06 | None | None | None | None | N | None | 1.38812E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.82733E-06 | 0 | 3.36666E-05 |
| E/V | 33586 |
Ig-158 |
91 | None | 0.3873 | None | 0.248 | N | 0.611 | 0.325 | 0.407357902709 | gnomAD-4.0.0 | 1.20045E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31264E-06 | 0 | 0 |
| D/E | 35030 |
Ig-163 |
89 | rs72629789 |
0.3937 | -0.179 | 0.893 | N | 0.351 | 0.173 | 0.101711395817 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/E | 35030 |
Ig-163 |
89 | rs72629789 |
0.3937 | -0.179 | 0.893 | N | 0.351 | 0.173 | 0.101711395817 | gnomAD-4.0.0 | 6.84177E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| D/G | 35030 |
Ig-163 |
89 | rs773386284 |
0.719 | -0.747 | 0.998 | N | 0.749 | 0.517 | 0.388334884743 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| D/G | 35030 |
Ig-163 |
89 | rs773386284 |
0.719 | -0.747 | 0.998 | N | 0.749 | 0.517 | 0.388334884743 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 35030 |
Ig-163 |
89 | rs773386284 |
0.719 | -0.747 | 0.998 | N | 0.749 | 0.517 | 0.388334884743 | gnomAD-4.0.0 | 4.33747E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22717E-05 | None | 0 | 0 | 5.0853E-06 | 0 | 0 |
| D/H | 35030 |
Ig-163 |
89 | None | 0.666 | None | 1.0 | N | 0.731 | 0.433 | 0.392395365052 | gnomAD-4.0.0 | 6.84167E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99402E-07 | 0 | 0 |
| D/N | 35030 |
Ig-163 |
89 | rs1689108955 |
0.3207 | None | 0.999 | N | 0.715 | 0.333 | 0.329540904979 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/N | 35030 |
Ig-163 |
89 | rs1689108955 |
0.3207 | None | 0.999 | N | 0.715 | 0.333 | 0.329540904979 | gnomAD-4.0.0 | 4.95718E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78037E-06 | 0 | 0 |
| T/S | 35508 |
Ig-166 |
89 | None | 0.1331 | None | 0.785 | D | 0.531 | 0.179 | 0.326345978581 | gnomAD-4.0.0 | 6.94625E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0347E-07 | 0 | 0 |
| T/K | 35693 |
Ig-167 |
87 | None | 0.1428 | None | 0.002 | N | 0.327 | 0.178 | 0.0716867268079 | gnomAD-4.0.0 | 3.18511E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.54847E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 35693 |
Ig-167 |
87 | None | 0.3257 | None | 0.317 | N | 0.569 | 0.351 | 0.253726318573 | gnomAD-4.0.0 | 1.59245E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 0 | 0 | 0 |
| M/L | 35790 |
Ig-168 |
89 | rs1687416004 |
0.1228 | None | None | N | 0.135 | 0.119 | 0.367612772649 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/L | 35790 |
Ig-168 |
89 | rs1687416004 |
0.1228 | None | None | N | 0.135 | 0.119 | 0.367612772649 | gnomAD-4.0.0 | 6.5716E-06 | None | None | None | None | N | None | 2.41289E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/R | 35790 |
Ig-168 |
89 | rs1188337689 |
0.1489 | 1.085 | None | N | 0.173 | 0.11 | 0.192905019026 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| M/R | 35790 |
Ig-168 |
89 | rs1188337689 |
0.1489 | 1.085 | None | N | 0.173 | 0.11 | 0.192905019026 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| M/R | 35790 |
Ig-168 |
89 | rs1188337689 |
0.1489 | 1.085 | None | N | 0.173 | 0.11 | 0.192905019026 | gnomAD-4.0.0 | 2.56222E-06 | None | None | None | None | N | None | 3.38203E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/N | 35987 |
Ig-169 |
91 | rs2154129767 |
0.0445 | None | None | N | 0.097 | 0.113 | 0.242825505644 | gnomAD-4.0.0 | 4.80136E-06 | None | None | None | -0.332(OBSL1) -0.321(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25009E-06 | 0 | 0 |
| H/R | 35987 |
Ig-169 |
91 | rs761091731 |
0.1107 | -0.778 | 0.003 | N | 0.213 | 0.073 | 0.235038932564 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | -1.72(OBSL1) -1.595(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| H/R | 35987 |
Ig-169 |
91 | rs761091731 |
0.1107 | -0.778 | 0.003 | N | 0.213 | 0.073 | 0.235038932564 | gnomAD-4.0.0 | 1.36907E-06 | None | None | None | -1.72(OBSL1) -1.595(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99774E-07 | 0 | 1.65711E-05 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.