Structural position:
- Domain Type: Ig
- Aligned Position: 3
- Secondary Structure Element: e
- Secondary Structure Region: β-strand A
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F/I | 8 |
Ig-1 |
3 | None | 0.7673 | None | 1.0 | N | 0.781 | 0.606 | 0.58541340546 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | -3.121(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/C | 1293 |
Ig-5 |
3 | rs747818002 |
0.9898 | None | 1.0 | D | 0.872 | 0.9 | 0.874737625709 | gnomAD-4.0.0 | 1.3687E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79919E-06 | 0 | 0 |
| F/S | 1293 |
Ig-5 |
3 | rs747818002 |
0.9951 | -1.79 | 1.0 | D | 0.859 | 0.892 | 0.883322413553 | gnomAD-2.1.1 | 4E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.62E-05 | 0 | 0 |
| F/S | 1293 |
Ig-5 |
3 | rs747818002 |
0.9951 | -1.79 | 1.0 | D | 0.859 | 0.892 | 0.883322413553 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 9.43E-05 | 0 | 0 | 0 | 0 |
| F/S | 1293 |
Ig-5 |
3 | rs747818002 |
0.9951 | -1.79 | 1.0 | D | 0.859 | 0.892 | 0.883322413553 | gnomAD-4.0.0 | 3.71891E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 7.8147E-05 | 1.64474E-04 | 0 | 0 | 0 |
| F/Y | 1293 |
Ig-5 |
3 | None | 0.8263 | None | 0.999 | D | 0.646 | 0.702 | 0.661506781955 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| F/Y | 1293 |
Ig-5 |
3 | None | 0.8263 | None | 0.999 | D | 0.646 | 0.702 | 0.661506781955 | gnomAD-4.0.0 | 6.57307E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| F/L | 1705 |
Ig-8 |
3 | rs375828531 |
0.991 | -1.943 | 0.999 | D | 0.657 | 0.809 | 0.349429436713 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 6.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 1705 |
Ig-8 |
3 | rs375828531 |
0.991 | -1.943 | 0.999 | D | 0.657 | 0.809 | 0.349429436713 | gnomAD-4.0.0 | 1.57342E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.06837E-05 | 0 | 0 |
| I/T | 1843 |
Ig-9 |
3 | None | 0.8247 | None | 0.991 | D | 0.793 | 0.674 | 0.823937394785 | gnomAD-4.0.0 | 1.59108E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02151E-05 |
| I/V | 1843 |
Ig-9 |
3 | None | 0.1378 | None | 0.58 | N | 0.445 | 0.228 | 0.573784085325 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| F/L | 2176 |
Ig-11 |
3 | rs1423674252 |
0.9873 | -1.765 | 0.997 | D | 0.629 | 0.753 | 0.540334051544 | gnomAD-2.1.1 | 7.09E-06 | None | None | None | None | N | None | 0 | 5.65E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 2176 |
Ig-11 |
3 | rs1423674252 |
0.9873 | -1.765 | 0.997 | D | 0.629 | 0.753 | 0.540334051544 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.30941E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 2176 |
Ig-11 |
3 | rs1423674252 |
0.9873 | -1.765 | 0.997 | D | 0.629 | 0.753 | 0.540334051544 | gnomAD-4.0.0 | 5.12319E-06 | None | None | None | None | N | None | 0 | 6.77851E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 2269 |
Ig-12 |
3 | rs1340770955 |
0.8946 | -2.748 | 0.986 | D | 0.593 | 0.844 | 0.848023011964 | gnomAD-2.1.1 | 8.01E-06 | None | None | None | None | N | None | 6.2E-05 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/S | 2269 |
Ig-12 |
3 | rs1340770955 |
0.8946 | -2.748 | 0.986 | D | 0.593 | 0.844 | 0.848023011964 | gnomAD-4.0.0 | 3.18768E-06 | None | None | None | None | N | None | 5.65483E-05 | 2.28802E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 2358 |
Ig-13 |
3 | rs1175538754 |
0.1966 | None | 0.005 | N | 0.247 | 0.251 | 0.549839970675 | gnomAD-4.0.0 | 2.05229E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69793E-06 | 0 | 0 |
| I/M | 2358 |
Ig-13 |
3 | rs753536718 |
0.2646 | -0.574 | 0.976 | D | 0.486 | 0.485 | 0.563655836063 | gnomAD-2.1.1 | 4E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/M | 2358 |
Ig-13 |
3 | rs753536718 |
0.2646 | -0.574 | 0.976 | D | 0.486 | 0.485 | 0.563655836063 | gnomAD-4.0.0 | 1.59073E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| I/V | 2358 |
Ig-13 |
3 | rs1175538754 |
0.1039 | -0.476 | 0.509 | N | 0.365 | 0.223 | 0.662238901992 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 2358 |
Ig-13 |
3 | rs1175538754 |
0.1039 | -0.476 | 0.509 | N | 0.365 | 0.223 | 0.662238901992 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.30907E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 2358 |
Ig-13 |
3 | rs1175538754 |
0.1039 | -0.476 | 0.509 | N | 0.365 | 0.223 | 0.662238901992 | gnomAD-4.0.0 | 1.85876E-06 | None | None | None | None | N | None | 0 | 3.33378E-05 | None | 0 | 0 | None | 0 | 0 | 8.47462E-07 | 0 | 0 |
| V/M | 2447 |
Ig-14 |
3 | rs779064962 |
0.1588 | -0.634 | 0.953 | N | 0.685 | 0.233 | 0.534719010399 | gnomAD-2.1.1 | 2.84E-05 | None | None | None | None | N | None | 4.06E-05 | 5.65E-05 | None | 0 | 5.03E-05 | None | 3.27E-05 | None | 0 | 1.56E-05 | 1.39082E-04 |
| V/M | 2447 |
Ig-14 |
3 | rs779064962 |
0.1588 | -0.634 | 0.953 | N | 0.685 | 0.233 | 0.534719010399 | gnomAD-3.1.2 | 1.0518E-04 | None | None | None | None | N | None | 0 | 9.17672E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 4.78469E-04 |
| V/M | 2447 |
Ig-14 |
3 | rs779064962 |
0.1588 | -0.634 | 0.953 | N | 0.685 | 0.233 | 0.534719010399 | gnomAD-4.0.0 | 4.02757E-05 | None | None | None | None | N | None | 2.67008E-05 | 2.83522E-04 | None | 0 | 2.22936E-05 | None | 0 | 0 | 3.22043E-05 | 3.29366E-05 | 6.40184E-05 |
| I/V | 2622 |
Ig-16 |
2 | rs148394362 |
0.1357 | -1.257 | 0.993 | D | 0.456 | 0.46 | None | gnomAD-2.1.1 | 1.06E-05 | None | None | None | None | N | None | 4E-05 | 0 | None | 0 | 5.02E-05 | None | 0 | None | 0 | 7.76E-06 | 0 |
| I/V | 2622 |
Ig-16 |
2 | rs148394362 |
0.1357 | -1.257 | 0.993 | D | 0.456 | 0.46 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.9253E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 2622 |
Ig-16 |
2 | rs148394362 |
0.1357 | -1.257 | 0.993 | D | 0.456 | 0.46 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| I/V | 2622 |
Ig-16 |
2 | rs148394362 |
0.1357 | -1.257 | 0.993 | D | 0.456 | 0.46 | None | gnomAD-4.0.0 | 7.68443E-06 | None | None | None | None | N | None | 5.06141E-05 | 0 | None | 0 | 4.85084E-05 | None | 0 | 0 | 2.39283E-06 | 0 | 0 |
| I/S | 2709 |
Ig-17 |
3 | rs2091328773 |
0.8527 | None | 0.991 | D | 0.797 | 0.716 | 0.854516633281 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 2709 |
Ig-17 |
3 | rs2091328773 |
0.8527 | None | 0.991 | D | 0.797 | 0.716 | 0.854516633281 | gnomAD-4.0.0 | 6.56978E-06 | None | None | None | None | N | None | 0 | 6.5445E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 2797 |
Ig-18 |
3 | rs1561222466 |
0.9785 | None | 0.998 | D | 0.85 | 0.777 | 0.912926368446 | gnomAD-4.0.0 | 6.84065E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99289E-07 | 0 | 0 |
| I/T | 2797 |
Ig-18 |
3 | rs1561222466 |
0.9714 | None | 0.989 | D | 0.775 | 0.761 | 0.800972959348 | gnomAD-4.0.0 | 6.84065E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99289E-07 | 0 | 0 |
| I/V | 2884 |
Ig-19 |
3 | rs1390184716 |
0.1048 | -1.333 | 0.198 | N | 0.245 | 0.22 | 0.514923749907 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 2884 |
Ig-19 |
3 | rs1390184716 |
0.1048 | -1.333 | 0.198 | N | 0.245 | 0.22 | 0.514923749907 | gnomAD-4.0.0 | 2.05224E-06 | None | None | None | None | N | None | 0 | 2.23644E-05 | None | 0 | 0 | None | 0 | 0 | 1.79859E-06 | 0 | 0 |
| F/L | 3060 |
Ig-21 |
3 | None | 0.9975 | None | 0.999 | D | 0.61 | 0.77 | 0.341696514166 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/L | 3241 |
Ig-23 |
3 | rs777535305 |
0.1445 | -0.611 | None | N | 0.258 | 0.14 | 0.143124449307 | gnomAD-2.1.1 | 4E-06 | None | None | None | None | N | None | 6.19E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 3241 |
Ig-23 |
3 | rs777535305 |
0.1445 | -0.611 | None | N | 0.258 | 0.14 | 0.143124449307 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 3241 |
Ig-23 |
3 | rs777535305 |
0.1445 | -0.611 | None | N | 0.258 | 0.14 | 0.143124449307 | gnomAD-4.0.0 | 3.84561E-06 | None | None | None | None | N | None | 5.07563E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 3940 |
Ig-28 |
3 | rs1170680046 |
0.9622 | -2.051 | 0.999 | D | 0.67 | 0.804 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| F/L | 3940 |
Ig-28 |
3 | rs1170680046 |
0.9622 | -2.051 | 0.999 | D | 0.67 | 0.804 | None | gnomAD-4.0.0 | 1.59107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77269E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 4608 |
Ig-29 |
3 | None | 0.4102 | None | 0.062 | D | 0.567 | 0.42 | None | gnomAD-4.0.0 | 1.59118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85796E-06 | 0 | 0 |
| I/F | 4702 |
Ig-30 |
3 | rs545434193 |
0.1287 | -1.524 | 0.005 | N | 0.264 | 0.181 | 0.402614778071 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/F | 4702 |
Ig-30 |
3 | rs545434193 |
0.1287 | -1.524 | 0.005 | N | 0.264 | 0.181 | 0.402614778071 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/F | 4702 |
Ig-30 |
3 | rs545434193 |
0.1287 | -1.524 | 0.005 | N | 0.264 | 0.181 | 0.402614778071 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/F | 4702 |
Ig-30 |
3 | rs545434193 |
0.1287 | -1.524 | 0.005 | N | 0.264 | 0.181 | 0.402614778071 | gnomAD-4.0.0 | 6.56702E-06 | None | None | None | None | N | None | 2.40593E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 4702 |
Ig-30 |
3 | None | 0.1248 | None | 0.934 | N | 0.633 | 0.275 | 0.625177984591 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| F/C | 4797 |
Ig-31 |
3 | None | 0.9607 | None | 1.0 | D | 0.829 | 0.851 | 0.880808525782 | gnomAD-4.0.0 | 6.95456E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.09098E-07 | 0 | 0 |
| F/L | 4890 |
Ig-32 |
3 | None | 0.9418 | None | 0.76 | D | 0.643 | 0.539 | 0.423119698836 | gnomAD-4.0.0 | 6.84262E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99475E-07 | 0 | 0 |
| F/L | 5077 |
Ig-34 |
3 | rs777568519 |
0.9392 | -1.672 | 0.817 | D | 0.537 | 0.637 | 0.536240654335 | gnomAD-2.1.1 | 4.72E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.93E-05 | None | 0 | None | 0 | 0 | 0 |
| I/L | 5263 |
Ig-36 |
3 | rs1166030692 |
0.3208 | -0.561 | 0.689 | D | 0.489 | 0.221 | 0.415690173769 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| I/L | 5263 |
Ig-36 |
3 | rs1166030692 |
0.3208 | -0.561 | 0.689 | D | 0.489 | 0.221 | 0.415690173769 | gnomAD-4.0.0 | 1.60066E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77809E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/N | 5263 |
Ig-36 |
3 | rs776892266 |
0.8552 | -1.389 | 0.998 | D | 0.831 | 0.494 | 0.746474153379 | gnomAD-2.1.1 | 7.9E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 8.44459E-04 | 7.87E-06 | 0 |
| I/N | 5263 |
Ig-36 |
3 | rs776892266 |
0.8552 | -1.389 | 0.998 | D | 0.831 | 0.494 | 0.746474153379 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 4.71965E-04 | 0 | 0 | 0 | 0 |
| I/N | 5263 |
Ig-36 |
3 | rs776892266 |
0.8552 | -1.389 | 0.998 | D | 0.831 | 0.494 | 0.746474153379 | gnomAD-4.0.0 | 6.04903E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 7.07347E-04 | 0 | 0 | 0 | 5.71788E-05 |
| F/V | 5452 |
Ig-38 |
3 | None | 0.6647 | None | 1.0 | N | 0.772 | 0.666 | 0.869393105286 | gnomAD-4.0.0 | 1.64863E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.12617E-05 |
| F/L | 5545 |
Ig-39 |
3 | rs1372586778 |
0.9736 | -2.156 | 0.999 | N | 0.546 | 0.46 | 0.292062946507 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| F/L | 5545 |
Ig-39 |
3 | rs1372586778 |
0.9736 | -2.156 | 0.999 | N | 0.546 | 0.46 | 0.292062946507 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 5545 |
Ig-39 |
3 | rs1372586778 |
0.9736 | -2.156 | 0.999 | N | 0.546 | 0.46 | 0.292062946507 | gnomAD-4.0.0 | 3.04478E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20492E-06 | 0 | 6.80457E-05 |
| F/S | 5545 |
Ig-39 |
3 | rs999328804 |
0.9625 | None | 1.0 | N | 0.738 | 0.513 | 0.755701663775 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 5545 |
Ig-39 |
3 | rs999328804 |
0.9625 | None | 1.0 | N | 0.738 | 0.513 | 0.755701663775 | gnomAD-4.0.0 | 3.04492E-06 | None | None | None | None | N | None | 3.49516E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20495E-06 | 0 | 0 |
| I/V | 5825 |
Ig-42 |
3 | rs778914141 |
0.0948 | -1.331 | 0.4 | N | 0.281 | 0.217 | 0.516938183928 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 8.71E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 1.66168E-04 |
| I/V | 5825 |
Ig-42 |
3 | rs778914141 |
0.0948 | -1.331 | 0.4 | N | 0.281 | 0.217 | 0.516938183928 | gnomAD-4.0.0 | 1.11509E-05 | None | None | None | None | N | None | 0 | 1.14453E-04 | None | 0 | 0 | None | 0 | 0 | 5.72361E-06 | 0 | 0 |
| F/L | 5921 |
Ig-43 |
3 | rs758858348 |
0.9959 | -1.923 | 0.999 | D | 0.655 | 0.748 | 0.564354818415 | gnomAD-2.1.1 | 4.12E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.4E-05 | None | 0 | 0 | 0 |
| F/L | 5921 |
Ig-43 |
3 | rs758858348 |
0.9959 | -1.923 | 0.999 | D | 0.655 | 0.748 | 0.564354818415 | gnomAD-4.0.0 | 3.44378E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.61923E-06 | 1.17418E-05 | 0 |
| F/S | 6014 |
Ig-44 |
3 | None | 0.9568 | None | 0.998 | D | 0.847 | 0.773 | 0.847448009913 | gnomAD-4.0.0 | 1.62806E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.91812E-06 | 0 | 0 |
| F/L | 6294 |
Ig-47 |
3 | rs953595241 |
0.9843 | None | 0.999 | N | 0.683 | 0.661 | 0.3349148499 | gnomAD-4.0.0 | 6.9862E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.11281E-07 | 0 | 0 |
| I/F | 6387 |
Ig-48 |
3 | None | 0.5214 | None | 0.217 | N | 0.481 | 0.224 | 0.501810158561 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 6483 |
Ig-49 |
3 | rs373750655 |
0.9759 | -2.273 | 0.999 | D | 0.677 | 0.696 | 0.440498838766 | gnomAD-2.1.1 | 2.58E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 5.68E-05 | 0 |
| F/L | 6483 |
Ig-49 |
3 | rs373750655 |
0.9759 | -2.273 | 0.999 | D | 0.677 | 0.696 | 0.440498838766 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 6483 |
Ig-49 |
3 | rs373750655 |
0.9759 | -2.273 | 0.999 | D | 0.677 | 0.696 | 0.440498838766 | gnomAD-4.0.0 | 3.81018E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.02366E-05 | 0 | 3.23269E-05 |
| F/S | 6669 |
Ig-51 |
3 | None | 0.9854 | None | 1.0 | D | 0.837 | 0.724 | 0.875463282793 | gnomAD-4.0.0 | 1.63511E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.50281E-05 | 0 |
| F/V | 6856 |
Ig-53 |
3 | None | 0.6337 | None | 1.0 | D | 0.754 | 0.815 | 0.765320684573 | gnomAD-4.0.0 | 6.98616E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.12629E-07 | 0 | 0 |
| I/M | 6950 |
Ig-54 |
3 | rs772569345 |
0.3113 | -0.955 | 0.998 | D | 0.701 | 0.631 | 0.64410640661 | gnomAD-2.1.1 | 4.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.52E-05 | None | 0 | 0 | 0 |
| I/T | 6950 |
Ig-54 |
3 | rs1553914315 |
0.7788 | -1.917 | 0.989 | N | 0.795 | 0.597 | 0.78814157021 | gnomAD-2.1.1 | 1.25E-05 | None | None | None | None | N | None | 0 | 3.03E-05 | None | 0 | 0 | None | 7.06E-05 | None | 0 | 0 | 0 |
| I/T | 6950 |
Ig-54 |
3 | rs1553914315 |
0.7788 | -1.917 | 0.989 | N | 0.795 | 0.597 | 0.78814157021 | gnomAD-4.0.0 | 4.93517E-06 | None | None | None | None | N | None | 0 | 2.37643E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 2.95604E-05 | 0 |
| I/V | 6950 |
Ig-54 |
3 | rs549440035 |
0.1828 | -1.332 | 0.333 | D | 0.255 | 0.276 | 0.621920094586 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.1489E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 6950 |
Ig-54 |
3 | rs549440035 |
0.1828 | -1.332 | 0.333 | D | 0.255 | 0.276 | 0.621920094586 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 6950 |
Ig-54 |
3 | rs549440035 |
0.1828 | -1.332 | 0.333 | D | 0.255 | 0.276 | 0.621920094586 | gnomAD-4.0.0 | 1.97094E-05 | None | None | None | None | N | None | 4.81325E-05 | 6.54108E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 7139 |
Ig-56 |
3 | None | 0.9624 | None | 0.948 | N | 0.654 | 0.551 | 0.509521504481 | gnomAD-4.0.0 | 6.97654E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.69405E-05 |
| F/S | 7139 |
Ig-56 |
3 | rs374010248 |
0.9563 | None | 0.999 | D | 0.876 | 0.747 | 0.80943609516 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/S | 7139 |
Ig-56 |
3 | rs374010248 |
0.9563 | None | 0.999 | D | 0.876 | 0.747 | 0.80943609516 | gnomAD-4.0.0 | 2.52358E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.4246E-06 | 0 | 0 |
| F/Y | 7139 |
Ig-56 |
3 | rs374010248 |
0.5834 | -0.947 | 0.998 | D | 0.669 | 0.608 | None | gnomAD-2.1.1 | 5.97E-05 | None | None | None | None | N | None | 5.91266E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.59949E-04 |
| F/Y | 7139 |
Ig-56 |
3 | rs374010248 |
0.5834 | -0.947 | 0.998 | D | 0.669 | 0.608 | None | gnomAD-3.1.2 | 5.91E-05 | None | None | None | None | N | None | 2.17129E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/Y | 7139 |
Ig-56 |
3 | rs374010248 |
0.5834 | -0.947 | 0.998 | D | 0.669 | 0.608 | None | gnomAD-4.0.0 | 1.51403E-05 | None | None | None | None | N | None | 2.84784E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.90549E-05 |
| F/L | 7232 |
Ig-57 |
3 | None | 0.9769 | None | 0.994 | N | 0.666 | 0.566 | 0.578358932345 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.17284E-04 | 0 | 0 | 0 |
| F/V | 7232 |
Ig-57 |
3 | rs776163887 |
0.7722 | -2.55 | 0.998 | D | 0.806 | 0.632 | 0.874471701311 | gnomAD-2.1.1 | 4.88E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.97377E-04 | None | 0 | 0 | 0 |
| F/V | 7232 |
Ig-57 |
3 | rs776163887 |
0.7722 | -2.55 | 0.998 | D | 0.806 | 0.632 | 0.874471701311 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 8.27472E-04 | 0 |
| F/V | 7232 |
Ig-57 |
3 | rs776163887 |
0.7722 | -2.55 | 0.998 | D | 0.806 | 0.632 | 0.874471701311 | gnomAD-4.0.0 | 2.10943E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.63484E-04 | 1.60359E-05 |
| F/L | 7325 |
Ig-58 |
3 | None | 0.9431 | None | 0.998 | N | 0.647 | 0.713 | 0.523082183605 | gnomAD-4.0.0 | 1.60027E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.04062E-05 |
| F/V | 7325 |
Ig-58 |
3 | None | 0.6356 | None | 0.999 | N | 0.737 | 0.712 | 0.8835682466 | gnomAD-4.0.0 | 6.8582E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00815E-07 | 0 | 0 |
| F/S | 7421 |
Ig-59 |
3 | rs1291566645 |
0.9854 | -2.346 | 1.0 | D | 0.873 | 0.803 | 0.890317696461 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| F/S | 7421 |
Ig-59 |
3 | rs1291566645 |
0.9854 | -2.346 | 1.0 | D | 0.873 | 0.803 | 0.890317696461 | gnomAD-4.0.0 | 1.59516E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.775E-05 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 7704 |
Ig-62 |
3 | rs2078208221 |
0.9896 | None | 0.06 | N | 0.335 | 0.476 | 0.390531646278 | gnomAD-4.0.0 | 1.6605E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.55284E-05 | 0 |
| F/L | 7797 |
Ig-63 |
3 | rs754815317 |
0.9822 | None | 0.987 | D | 0.663 | 0.716 | 0.374255764437 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 7797 |
Ig-63 |
3 | rs754815317 |
0.9822 | None | 0.987 | D | 0.663 | 0.716 | 0.374255764437 | gnomAD-4.0.0 | 7.45733E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01957E-05 | 0 | 0 |
| F/Y | 8266 |
Ig-68 |
3 | rs768252647 |
0.6969 | -1.033 | 0.999 | D | 0.657 | 0.623 | 0.851514812675 | gnomAD-2.1.1 | 8.33E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| F/Y | 8266 |
Ig-68 |
3 | rs768252647 |
0.6969 | -1.033 | 0.999 | D | 0.657 | 0.623 | 0.851514812675 | gnomAD-4.0.0 | 1.78772E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 2.2172E-05 | 0 | 2.5959E-05 | 0 | 3.05045E-05 |
| F/I | 8738 |
Ig-73 |
3 | rs1335039200 |
0.3658 | -2.089 | 1.0 | N | 0.771 | 0.663 | 0.497613835824 | gnomAD-2.1.1 | 1.24E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.1302E-04 | None | 0 | None | 4.85E-05 | 0 | 0 |
| F/I | 8738 |
Ig-73 |
3 | rs1335039200 |
0.3658 | -2.089 | 1.0 | N | 0.771 | 0.663 | 0.497613835824 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 0 | 0 | 0 |
| F/I | 8738 |
Ig-73 |
3 | rs1335039200 |
0.3658 | -2.089 | 1.0 | N | 0.771 | 0.663 | 0.497613835824 | gnomAD-4.0.0 | 1.12549E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.03932E-04 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 8738 |
Ig-73 |
3 | rs1304792247 |
0.8659 | None | 1.0 | D | 0.847 | 0.753 | 0.887337171484 | gnomAD-4.0.0 | 1.62391E-06 | None | None | None | None | N | None | 0 | 2.32428E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/S | 8832 |
Ig-74 |
3 | None | 0.7404 | None | 0.998 | D | 0.823 | 0.736 | 0.908569977246 | gnomAD-4.0.0 | 1.37166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80133E-06 | 0 | 0 |
| I/T | 8832 |
Ig-74 |
3 | rs748198284 |
0.4237 | -2.496 | 0.998 | D | 0.808 | 0.704 | 0.808517472782 | gnomAD-2.1.1 | 3.25E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.47678E-04 | None | 0 | None | 0 | 0 | 0 |
| I/T | 8832 |
Ig-74 |
3 | rs748198284 |
0.4237 | -2.496 | 0.998 | D | 0.808 | 0.704 | 0.808517472782 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/T | 8832 |
Ig-74 |
3 | rs748198284 |
0.4237 | -2.496 | 0.998 | D | 0.808 | 0.704 | 0.808517472782 | gnomAD-4.0.0 | 1.49047E-05 | None | None | None | None | N | None | 1.34023E-05 | 0 | None | 0 | 1.7842E-04 | None | 0 | 0 | 1.27301E-05 | 0 | 0 |
| I/V | 8832 |
Ig-74 |
3 | rs72648989 |
0.0743 | -1.448 | 0.91 | N | 0.546 | 0.144 | None | gnomAD-2.1.1 | 7.57335E-04 | None | None | None | None | N | None | 2.90964E-04 | 1.72315E-04 | None | 0 | 0 | None | 9.83251E-04 | None | 4.00994E-04 | 1.19407E-03 | 8.51789E-04 |
| I/V | 8832 |
Ig-74 |
3 | rs72648989 |
0.0743 | -1.448 | 0.91 | N | 0.546 | 0.144 | None | gnomAD-3.1.2 | 8.01809E-04 | None | None | None | None | N | None | 3.61969E-04 | 1.96489E-04 | 0 | 0 | 0 | None | 2.82752E-04 | 0 | 1.44058E-03 | 6.21375E-04 | 0 |
| I/V | 8832 |
Ig-74 |
3 | rs72648989 |
0.0743 | -1.448 | 0.91 | N | 0.546 | 0.144 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| I/V | 8832 |
Ig-74 |
3 | rs72648989 |
0.0743 | -1.448 | 0.91 | N | 0.546 | 0.144 | None | gnomAD-4.0.0 | 1.39471E-03 | None | None | None | None | N | None | 3.34439E-04 | 1.84657E-04 | None | 0 | 0 | None | 5.31416E-04 | 9.94365E-04 | 1.71177E-03 | 1.07565E-03 | 8.98934E-04 |
| F/L | 8928 |
Ig-75 |
3 | None | 0.9886 | None | 0.999 | N | 0.665 | 0.681 | 0.584023569625 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/L | 9021 |
Ig-76 |
3 | rs754185678 |
0.9574 | -1.713 | 0.948 | N | 0.649 | 0.701 | 0.448696893172 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| F/L | 9021 |
Ig-76 |
3 | rs754185678 |
0.9574 | -1.713 | 0.948 | N | 0.649 | 0.701 | 0.448696893172 | gnomAD-4.0.0 | 1.59495E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86541E-06 | 0 | 0 |
| F/L | 9114 |
Ig-77 |
3 | None | 0.9732 | None | 0.999 | D | 0.563 | 0.75 | 0.604764006798 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/V | 9207 |
Ig-78 |
3 | rs765453217 |
0.4279 | -2.146 | 1.0 | N | 0.751 | 0.778 | 0.877337478775 | gnomAD-2.1.1 | 1.79E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.31148E-04 | None | 0 | 7.83E-06 | 0 |
| F/V | 9207 |
Ig-78 |
3 | rs765453217 |
0.4279 | -2.146 | 1.0 | N | 0.751 | 0.778 | 0.877337478775 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 2.06954E-04 | 0 |
| F/V | 9207 |
Ig-78 |
3 | rs765453217 |
0.4279 | -2.146 | 1.0 | N | 0.751 | 0.778 | 0.877337478775 | gnomAD-4.0.0 | 1.79798E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.93583E-04 | 8.47994E-07 | 2.19785E-04 | 8.00974E-05 |
| F/I | 9399 |
Ig-80 |
3 | None | 0.7171 | None | 0.4 | None | 0.429 | 0.426 | 0.41883969893 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| F/L | 9495 |
Ig-81 |
3 | None | 0.9844 | None | 0.999 | None | 0.568 | 0.709 | 0.558774299873 | gnomAD-4.0.0 | 1.59569E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.90244E-05 | 0 | 0 | 0 | 0 |
| L/R | 9902 |
Ig-84 |
3 | rs1430193759 |
0.9065 | None | 0.999 | None | 0.758 | 0.487 | 0.652799619513 | gnomAD-4.0.0 | 1.60219E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86533E-06 | 0 | 0 |
| L/V | 9902 |
Ig-84 |
3 | None | 0.2973 | None | 0.198 | None | 0.365 | 0.119 | 0.285316908763 | gnomAD-4.0.0 | 1.60252E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86599E-06 | 0 | 0 |
| F/S | 13685 |
Ig-87 |
2 | None | 0.9992 | None | 1.0 | D | 0.6 | 0.834 | 0.87862966783 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/M | 13876 |
Ig-89 |
1 | None | 0.3784 | None | 0.997 | N | 0.697 | 0.144 | 0.422524665647 | gnomAD-4.0.0 | 1.62411E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9098E-06 | 0 | 0 |
| F/L | 14056 |
Ig-91 |
3 | rs1474422218 |
0.9881 | -2.202 | 0.999 | D | 0.6 | 0.633 | 0.451023696535 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| F/L | 14056 |
Ig-91 |
3 | rs1474422218 |
0.9881 | -2.202 | 0.999 | D | 0.6 | 0.633 | 0.451023696535 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 14056 |
Ig-91 |
3 | rs1474422218 |
0.9881 | -2.202 | 0.999 | D | 0.6 | 0.633 | 0.451023696535 | gnomAD-4.0.0 | 2.56439E-06 | None | None | None | None | N | None | 0 | 1.69768E-05 | None | 0 | 2.42718E-05 | None | 0 | 0 | 0 | 0 | 0 |
| F/I | 14144 |
Ig-92 |
3 | rs1359996660 |
0.5964 | -1.49 | 1.0 | N | 0.753 | 0.617 | 0.556145022309 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/I | 14144 |
Ig-92 |
3 | rs1359996660 |
0.5964 | -1.49 | 1.0 | N | 0.753 | 0.617 | 0.556145022309 | gnomAD-4.0.0 | 1.59352E-06 | None | None | None | None | N | None | 0 | 2.28791E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 14410 |
Ig-95 |
3 | rs759684544 |
0.9683 | -1.346 | 0.247 | D | 0.644 | 0.626 | 0.513958542087 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 14410 |
Ig-95 |
3 | rs759684544 |
0.9683 | -1.346 | 0.247 | D | 0.644 | 0.626 | 0.513958542087 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 14410 |
Ig-95 |
3 | rs759684544 |
0.9683 | -1.346 | 0.247 | D | 0.644 | 0.626 | 0.513958542087 | gnomAD-4.0.0 | 5.12985E-06 | None | None | None | None | N | None | 6.76933E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 14499 |
Ig-96 |
3 | rs754004380 |
0.9694 | -1.827 | 0.999 | D | 0.619 | 0.674 | 0.374613414588 | gnomAD-4.0.0 | 3.30061E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.87478E-06 | 0 | 0 |
| L/P | 14677 |
Ig-98 |
3 | None | 0.6047 | None | 0.828 | N | 0.839 | 0.367 | 0.538974603628 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 14677 |
Ig-98 |
3 | None | 0.1061 | None | None | N | 0.133 | 0.069 | 0.180583059064 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/I | 14766 |
Ig-99 |
2 | None | 0.1515 | None | 0.999 | N | 0.483 | 0.321 | 0.643463202348 | gnomAD-4.0.0 | 1.59344E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86246E-06 | 0 | 0 |
| F/L | 14855 |
Ig-100 |
3 | rs1424075362 |
0.9968 | -2.721 | 0.369 | D | 0.605 | 0.613 | 0.382592752248 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| F/L | 14855 |
Ig-100 |
3 | rs1424075362 |
0.9968 | -2.721 | 0.369 | D | 0.605 | 0.613 | 0.382592752248 | gnomAD-4.0.0 | 1.59464E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86449E-06 | 0 | 0 |
| F/S | 14944 |
Ig-101 |
3 | None | 0.9934 | None | 0.999 | D | 0.827 | 0.792 | 0.857761757952 | gnomAD-4.0.0 | 1.37943E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80824E-06 | 0 | 0 |
| I/M | 15210 |
Ig-104 |
3 | None | 0.1437 | None | 0.999 | D | 0.711 | 0.53 | 0.554356711338 | gnomAD-4.0.0 | 1.37185E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.8007E-06 | 0 | 0 |
| I/N | 15210 |
Ig-104 |
3 | rs193086479 |
0.8085 | -2.389 | 0.999 | D | 0.861 | 0.732 | None | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.68E-05 | None | 0 | None | 0 | 0 | 0 |
| I/N | 15210 |
Ig-104 |
3 | rs193086479 |
0.8085 | -2.389 | 0.999 | D | 0.861 | 0.732 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94628E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/N | 15210 |
Ig-104 |
3 | rs193086479 |
0.8085 | -2.389 | 0.999 | D | 0.861 | 0.732 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| I/N | 15210 |
Ig-104 |
3 | rs193086479 |
0.8085 | -2.389 | 0.999 | D | 0.861 | 0.732 | None | gnomAD-4.0.0 | 6.57808E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.95084E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 15210 |
Ig-104 |
3 | None | 0.1066 | None | 0.333 | N | 0.205 | 0.153 | 0.40218521252 | gnomAD-4.0.0 | 1.37187E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80071E-06 | 0 | 0 |
| F/L | 15393 |
Ig-106 |
3 | rs1301808455 |
0.9919 | -1.917 | 0.999 | D | 0.601 | 0.712 | 0.53371040847 | gnomAD-2.1.1 | 1.25E-05 | None | None | None | None | N | None | 0 | 8.96E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 15393 |
Ig-106 |
3 | rs1301808455 |
0.9919 | -1.917 | 0.999 | D | 0.601 | 0.712 | 0.53371040847 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 1.31389E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 15393 |
Ig-106 |
3 | rs1301808455 |
0.9919 | -1.917 | 0.999 | D | 0.601 | 0.712 | 0.53371040847 | gnomAD-4.0.0 | 6.51383E-06 | None | None | None | None | N | None | 0 | 8.61683E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 15393 |
Ig-106 |
3 | rs1157527811 |
0.9951 | None | 1.0 | D | 0.843 | 0.819 | 0.865896427254 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/S | 15393 |
Ig-106 |
3 | rs1157527811 |
0.9951 | None | 1.0 | D | 0.843 | 0.819 | 0.865896427254 | gnomAD-4.0.0 | 1.31664E-05 | None | None | None | None | N | None | 0 | 6.5703E-05 | None | 0 | 0 | None | 0 | 0 | 1.47236E-05 | 0 | 0 |
| F/L | 15968 |
Ig-109 |
1 | rs1261511850 |
0.9749 | -0.775 | 0.999 | N | 0.548 | 0.481 | 0.390687800842 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.97E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 15968 |
Ig-109 |
1 | rs1261511850 |
0.9749 | -0.775 | 0.999 | N | 0.548 | 0.481 | 0.390687800842 | gnomAD-4.0.0 | 1.5937E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.77646E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 16264 |
Ig-110 |
3 | rs1243976427 |
0.4879 | -0.314 | 0.999 | N | 0.581 | 0.209 | 0.633221168995 | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | N | None | 0 | 1.17786E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/V | 16264 |
Ig-110 |
3 | rs1243976427 |
0.4879 | -0.314 | 0.999 | N | 0.581 | 0.209 | 0.633221168995 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 1.31285E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 16264 |
Ig-110 |
3 | rs1243976427 |
0.4879 | -0.314 | 0.999 | N | 0.581 | 0.209 | 0.633221168995 | gnomAD-4.0.0 | 6.43784E-06 | None | None | None | None | N | None | 0 | 8.5473E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/F | 16957 |
Ig-111 |
3 | rs372013419 |
0.292 | -1.583 | 0.934 | N | 0.704 | 0.251 | 0.463328977263 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| I/F | 16957 |
Ig-111 |
3 | rs372013419 |
0.292 | -1.583 | 0.934 | N | 0.704 | 0.251 | 0.463328977263 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/F | 16957 |
Ig-111 |
3 | rs372013419 |
0.292 | -1.583 | 0.934 | N | 0.704 | 0.251 | 0.463328977263 | gnomAD-4.0.0 | 1.24066E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69616E-06 | 0 | 0 |
| I/N | 16957 |
Ig-111 |
3 | rs368450275 |
0.9103 | -1.759 | 0.989 | D | 0.845 | 0.675 | 0.803589953288 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | I | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 16957 |
Ig-111 |
3 | rs368450275 |
0.4464 | -2.236 | 0.801 | D | 0.707 | 0.542 | None | gnomAD-2.1.1 | 2.84E-05 | None | None | None | None | I | None | 0 | 0 | None | 9.98E-05 | 0 | None | 0 | None | 0 | 5.37E-05 | 0 |
| I/T | 16957 |
Ig-111 |
3 | rs368450275 |
0.4464 | -2.236 | 0.801 | D | 0.707 | 0.542 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/T | 16957 |
Ig-111 |
3 | rs368450275 |
0.4464 | -2.236 | 0.801 | D | 0.707 | 0.542 | None | gnomAD-4.0.0 | 9.92491E-06 | None | None | None | None | I | None | 0 | 0 | None | 3.38203E-05 | 2.24346E-05 | None | 7.8235E-05 | 0 | 6.78448E-06 | 1.10006E-05 | 0 |
| I/V | 16957 |
Ig-111 |
3 | rs372013419 |
0.0766 | -1.385 | 0.005 | N | 0.246 | 0.118 | None | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.67E-05 | 1.79E-05 | 1.67336E-04 |
| I/V | 16957 |
Ig-111 |
3 | rs372013419 |
0.0766 | -1.385 | 0.005 | N | 0.246 | 0.118 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 16957 |
Ig-111 |
3 | rs372013419 |
0.0766 | -1.385 | 0.005 | N | 0.246 | 0.118 | None | gnomAD-4.0.0 | 1.79895E-05 | None | None | None | None | I | None | 1.33636E-05 | 0 | None | 0 | 0 | None | 1.5647E-05 | 1.64799E-04 | 2.03539E-05 | 1.10028E-05 | 1.60364E-05 |
| L/P | 17253 |
Ig-112 |
3 | None | 0.9124 | None | 0.968 | N | 0.785 | 0.533 | 0.869023813792 | gnomAD-4.0.0 | 3.20605E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.76027E-06 | 0 | 0 |
| L/Q | 17253 |
Ig-112 |
3 | rs747840389 |
0.8545 | -0.36 | 0.83 | N | 0.775 | 0.442 | 0.805105696268 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | I | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/Q | 17253 |
Ig-112 |
3 | rs747840389 |
0.8545 | -0.36 | 0.83 | N | 0.775 | 0.442 | 0.805105696268 | gnomAD-4.0.0 | 1.60303E-06 | None | None | None | None | I | None | 0 | 2.2997E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/F | 17678 |
Ig-113 |
2 | rs1423968417 |
0.4963 | None | 1.0 | N | 0.747 | 0.333 | 0.815354353143 | gnomAD-4.0.0 | 1.59292E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.7804E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 17678 |
Ig-113 |
2 | None | 0.405 | None | 0.997 | N | 0.539 | 0.335 | 0.452640719197 | gnomAD-4.0.0 | 1.59292E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.861E-06 | 0 | 0 |
| S/I | 17970 |
Ig-114 |
3 | None | 0.1783 | None | 0.017 | N | 0.539 | 0.117 | 0.439975540334 | gnomAD-4.0.0 | 6.9269E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.06493E-07 | 0 | 0 |
| S/N | 17970 |
Ig-114 |
3 | rs368532455 |
0.1248 | -1.175 | 0.014 | N | 0.438 | 0.116 | None | gnomAD-2.1.1 | 4.31E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.42E-06 | 0 |
| S/N | 17970 |
Ig-114 |
3 | rs368532455 |
0.1248 | -1.175 | 0.014 | N | 0.438 | 0.116 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/N | 17970 |
Ig-114 |
3 | rs368532455 |
0.1248 | -1.175 | 0.014 | N | 0.438 | 0.116 | None | gnomAD-4.0.0 | 4.38723E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.97745E-06 | 0 | 0 |
| L/I | 18690 |
Ig-116 |
3 | None | 0.1886 | None | 0.999 | N | 0.517 | 0.355 | 0.490352026379 | gnomAD-4.0.0 | 1.65436E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94301E-06 | 0 | 0 |
| M/V | 19792 |
Ig-119 |
3 | None | 0.4377 | None | 0.985 | N | 0.482 | 0.367 | 0.621112526605 | gnomAD-4.0.0 | 1.59254E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43345E-05 | 0 |
| V/E | 20082 |
Ig-120 |
3 | None | 0.8309 | None | 0.928 | D | 0.753 | 0.356 | 0.715013705373 | gnomAD-4.0.0 | 6.97569E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.06842E-07 | 0 | 0 |
| V/G | 20082 |
Ig-120 |
3 | None | 0.6089 | None | 0.864 | N | 0.721 | 0.38 | 0.723455425128 | gnomAD-4.0.0 | 6.97572E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.23937E-05 | 0 |
| T/S | 20481 |
Ig-121 |
3 | None | 0.1198 | None | 0.885 | N | 0.508 | 0.066 | 0.208816687407 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 20771 |
Ig-122 |
3 | rs1384039456 |
0.7821 | -1.134 | 0.998 | N | 0.624 | 0.286 | 0.547168864562 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| L/F | 20771 |
Ig-122 |
3 | rs1384039456 |
0.7821 | -1.134 | 0.998 | N | 0.624 | 0.286 | 0.547168864562 | gnomAD-4.0.0 | 6.84345E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99556E-07 | 0 | 0 |
| L/R | 20771 |
Ig-122 |
3 | rs2049747701 |
0.9866 | None | 0.999 | N | 0.71 | 0.591 | 0.850017294419 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/R | 20771 |
Ig-122 |
3 | rs2049747701 |
0.9866 | None | 0.999 | N | 0.71 | 0.591 | 0.850017294419 | gnomAD-4.0.0 | 6.57765E-06 | None | None | None | None | N | None | 2.41441E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 20771 |
Ig-122 |
3 | None | 0.1855 | None | 0.543 | N | 0.377 | 0.187 | 0.326074293725 | gnomAD-4.0.0 | 2.73738E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59822E-06 | 0 | 0 |
| S/G | 21179 |
Ig-123 |
3 | rs772529311 |
0.1095 | 0.108 | 0.011 | N | 0.239 | 0.213 | 0.28798054836 | gnomAD-2.1.1 | 1.24E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.64E-05 | None | 0 | None | 0 | 1.82E-05 | 0 |
| S/G | 21179 |
Ig-123 |
3 | rs772529311 |
0.1095 | 0.108 | 0.011 | N | 0.239 | 0.213 | 0.28798054836 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/G | 21179 |
Ig-123 |
3 | rs772529311 |
0.1095 | 0.108 | 0.011 | N | 0.239 | 0.213 | 0.28798054836 | gnomAD-4.0.0 | 6.85293E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 6.73129E-05 | None | 0 | 0 | 5.95919E-06 | 0 | 1.61119E-05 |
| L/F | 21471 |
Ig-124 |
3 | rs774609456 |
0.1739 | -0.988 | 0.994 | N | 0.563 | 0.174 | 0.470970234271 | gnomAD-2.1.1 | 4.44E-05 | None | None | None | None | N | None | 0 | 3.50853E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/F | 21471 |
Ig-124 |
3 | rs774609456 |
0.1739 | -0.988 | 0.994 | N | 0.563 | 0.174 | 0.470970234271 | gnomAD-4.0.0 | 2.17757E-05 | None | None | None | None | N | None | 0 | 3.51922E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 21868 |
Ig-125 |
3 | None | 0.1283 | None | 0.055 | N | 0.269 | 0.066 | 0.352910780287 | gnomAD-4.0.0 | 1.60556E-06 | None | None | None | None | N | None | 0 | 2.29811E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 22267 |
Ig-126 |
3 | None | 0.6172 | None | 0.967 | D | 0.719 | 0.233 | 0.567747928639 | gnomAD-4.0.0 | 6.00161E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 0 |
| L/V | 22267 |
Ig-126 |
3 | rs2047467228 |
0.4508 | None | 0.099 | N | 0.369 | 0.228 | 0.260249123532 | gnomAD-4.0.0 | 1.37066E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80022E-06 | 0 | 0 |
| I/V | 22952 |
Ig-128 |
3 | rs2046685725 |
0.0728 | None | 0.007 | N | 0.233 | 0.058 | 0.32580497728 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 22952 |
Ig-128 |
3 | rs2046685725 |
0.0728 | None | 0.007 | N | 0.233 | 0.058 | 0.32580497728 | gnomAD-4.0.0 | 3.76378E-06 | None | None | None | None | N | None | 0 | 3.3653E-05 | None | 0 | 0 | None | 0 | 0 | 3.42608E-06 | 0 | 0 |
| D/G | 23347 |
Ig-129 |
3 | rs1484649738 |
0.7107 | None | 0.955 | N | 0.653 | 0.584 | 0.424908009808 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 23347 |
Ig-129 |
3 | rs1484649738 |
0.7107 | None | 0.955 | N | 0.653 | 0.584 | 0.424908009808 | gnomAD-4.0.0 | 6.57626E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47111E-05 | 0 | 0 |
| D/H | 23347 |
Ig-129 |
3 | rs371752797 |
0.9114 | 0.547 | 0.999 | N | 0.738 | 0.557 | None | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.04E-05 | 1.40647E-04 |
| D/H | 23347 |
Ig-129 |
3 | rs371752797 |
0.9114 | 0.547 | 0.999 | N | 0.738 | 0.557 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| D/H | 23347 |
Ig-129 |
3 | rs371752797 |
0.9114 | 0.547 | 0.999 | N | 0.738 | 0.557 | None | gnomAD-4.0.0 | 6.13619E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.05352E-05 | 0 | 6.40533E-05 |
| Y/H | 23639 |
Ig-130 |
3 | None | 0.3302 | None | 0.998 | N | 0.722 | 0.362 | 0.450343601259 | gnomAD-4.0.0 | 6.846E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99701E-07 | 0 | 0 |
| V/A | 24031 |
Ig-131 |
3 | None | 0.217 | None | 0.103 | N | 0.145 | 0.261 | 0.589635058153 | gnomAD-4.0.0 | 3.18428E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71991E-06 | 0 | 0 |
| F/L | 24718 |
Ig-133 |
3 | rs773802084 |
0.8633 | -1.364 | 0.006 | N | 0.308 | 0.433 | 0.411001663086 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| F/L | 24718 |
Ig-133 |
3 | rs773802084 |
0.8633 | -1.364 | 0.006 | N | 0.308 | 0.433 | 0.411001663086 | gnomAD-4.0.0 | 3.18498E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71935E-06 | 0 | 0 |
| F/S | 24718 |
Ig-133 |
3 | None | 0.8226 | None | 0.97 | D | 0.832 | 0.723 | 0.862802660111 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| M/T | 25113 |
Ig-134 |
3 | rs1707917158 |
0.4335 | None | 0.285 | N | 0.296 | 0.325 | 0.627559020554 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| M/T | 25113 |
Ig-134 |
3 | rs1707917158 |
0.4335 | None | 0.285 | N | 0.296 | 0.325 | 0.627559020554 | gnomAD-4.0.0 | 2.03007E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40998E-06 | 0 | 0 |
| L/I | 25516 |
Ig-135 |
3 | rs752300467 |
0.3414 | -0.674 | 0.992 | N | 0.529 | 0.276 | 0.317958651998 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.83E-05 | None | 0 | 0 | 0 |
| L/I | 25516 |
Ig-135 |
3 | rs752300467 |
0.3414 | -0.674 | 0.992 | N | 0.529 | 0.276 | 0.317958651998 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07641E-04 | 0 |
| L/I | 25516 |
Ig-135 |
3 | rs752300467 |
0.3414 | -0.674 | 0.992 | N | 0.529 | 0.276 | 0.317958651998 | gnomAD-4.0.0 | 6.20099E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09878E-04 | 0 |
| V/A | 25800 |
Ig-136 |
3 | None | 0.3733 | None | 0.994 | N | 0.54 | 0.408 | 0.55767489547 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| M/V | 26195 |
Ig-137 |
3 | rs369118365 |
0.1379 | -0.595 | 0.01 | N | 0.058 | 0.195 | None | gnomAD-2.1.1 | 2.53E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.95E-05 | 1.42776E-04 |
| M/V | 26195 |
Ig-137 |
3 | rs369118365 |
0.1379 | -0.595 | 0.01 | N | 0.058 | 0.195 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| M/V | 26195 |
Ig-137 |
3 | rs369118365 |
0.1379 | -0.595 | 0.01 | N | 0.058 | 0.195 | None | gnomAD-4.0.0 | 1.49076E-05 | None | None | None | None | N | None | 1.33701E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.95254E-05 | 0 | 0 |
| D/N | 27678 |
Ig-141 |
3 | rs781128731 |
0.7336 | -0.294 | 1.0 | D | 0.672 | 0.46 | 0.446111551642 | gnomAD-2.1.1 | 3.62E-05 | None | None | None | None | N | None | 0 | 1.73812E-04 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.78E-05 | 0 |
| D/N | 27678 |
Ig-141 |
3 | rs781128731 |
0.7336 | -0.294 | 1.0 | D | 0.672 | 0.46 | 0.446111551642 | gnomAD-4.0.0 | 1.36846E-05 | None | None | None | None | N | None | 0 | 1.11802E-04 | None | 0 | 0 | None | 0 | 0 | 1.25933E-05 | 1.15937E-05 | 0 |
| V/A | 27965 |
Ig-142 |
3 | rs1284864788 |
0.2139 | -1.823 | 0.004 | D | 0.302 | 0.25 | 0.357519025918 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/A | 27965 |
Ig-142 |
3 | rs1284864788 |
0.2139 | -1.823 | 0.004 | D | 0.302 | 0.25 | 0.357519025918 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 27965 |
Ig-142 |
3 | rs1284864788 |
0.2139 | -1.823 | 0.004 | D | 0.302 | 0.25 | 0.357519025918 | gnomAD-4.0.0 | 2.56472E-06 | None | None | None | None | I | None | 3.38558E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 27965 |
Ig-142 |
3 | rs1321140287 |
0.0814 | -0.319 | 0.002 | N | 0.244 | 0.076 | 0.332902724076 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| V/I | 27965 |
Ig-142 |
3 | rs1321140287 |
0.0814 | -0.319 | 0.002 | N | 0.244 | 0.076 | 0.332902724076 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/I | 27965 |
Ig-142 |
3 | rs1321140287 |
0.0814 | -0.319 | 0.002 | N | 0.244 | 0.076 | 0.332902724076 | gnomAD-4.0.0 | 3.10005E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23903E-06 | 0 | 0 |
| D/H | 28360 |
Ig-143 |
3 | None | 0.7807 | None | 0.901 | D | 0.457 | 0.624 | 0.489104616352 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/A | 28757 |
Ig-144 |
3 | rs778722165 |
0.2549 | -0.37 | 0.9 | N | 0.481 | 0.343 | 0.426551566703 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.96297E-04 | None | 0 | 8.89E-06 | 0 |
| D/A | 28757 |
Ig-144 |
3 | rs778722165 |
0.2549 | -0.37 | 0.9 | N | 0.481 | 0.343 | 0.426551566703 | gnomAD-4.0.0 | 1.43843E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 3.47343E-04 | 3.59798E-06 | 1.62368E-04 | 1.65667E-05 |
| D/G | 28757 |
Ig-144 |
3 | rs778722165 |
0.1983 | -0.922 | 0.978 | N | 0.479 | 0.4 | 0.373173300195 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| D/N | 28757 |
Ig-144 |
3 | rs946879778 |
0.1415 | -0.455 | 0.978 | N | 0.509 | 0.352 | 0.352476196916 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 3.32447E-04 |
| D/N | 28757 |
Ig-144 |
3 | rs946879778 |
0.1415 | -0.455 | 0.978 | N | 0.509 | 0.352 | 0.352476196916 | gnomAD-4.0.0 | 4.10978E-06 | None | None | None | None | N | None | 0 | 2.23674E-05 | None | 0 | 0 | None | 0 | 0 | 4.49751E-06 | 0 | 0 |
| K/N | 29047 |
Ig-145 |
3 | rs1702242034 |
0.2662 | None | 0.864 | N | 0.534 | 0.196 | 0.225215365344 | gnomAD-4.0.0 | 1.60761E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86852E-06 | 0 | 0 |
| K/R | 29047 |
Ig-145 |
3 | None | 0.0753 | None | 0.013 | N | 0.322 | 0.087 | 0.32714864917 | gnomAD-4.0.0 | 1.56044E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.70627E-05 | 0 | 0 |
| A/T | 30929 |
Ig-150 |
3 | rs1192451781 |
0.153 | -0.492 | 1.0 | D | 0.632 | 0.296 | 0.344945010812 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| A/T | 30929 |
Ig-150 |
3 | rs1192451781 |
0.153 | -0.492 | 1.0 | D | 0.632 | 0.296 | 0.344945010812 | gnomAD-4.0.0 | 6.37127E-06 | None | None | None | None | N | None | 0 | 6.85997E-05 | None | 0 | 2.77469E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 32019 |
Ig-153 |
3 | rs786205366 |
0.2012 | -0.277 | 0.619 | N | 0.376 | 0.068 | 0.266843984389 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/E | 32019 |
Ig-153 |
3 | rs786205366 |
0.2012 | -0.277 | 0.619 | N | 0.376 | 0.068 | 0.266843984389 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 32019 |
Ig-153 |
3 | rs786205366 |
0.2012 | -0.277 | 0.619 | N | 0.376 | 0.068 | 0.266843984389 | gnomAD-4.0.0 | 6.57212E-06 | None | None | None | None | N | None | 2.41371E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 32309 |
Ig-154 |
3 | None | 0.4611 | None | 0.966 | N | 0.332 | 0.332 | 0.294561560033 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/H | 32710 |
Ig-155 |
3 | None | 0.4314 | None | 1.0 | D | 0.677 | 0.459 | 0.530160902827 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/K | 33103 |
Ig-156 |
3 | rs1251000688 |
0.5997 | -1.215 | 0.009 | D | 0.714 | 0.55 | 0.852493086899 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 6.53E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/K | 33103 |
Ig-156 |
3 | rs1251000688 |
0.5997 | -1.215 | 0.009 | D | 0.714 | 0.55 | 0.852493086899 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/K | 33103 |
Ig-156 |
3 | rs1251000688 |
0.5997 | -1.215 | 0.009 | D | 0.714 | 0.55 | 0.852493086899 | gnomAD-4.0.0 | 1.97153E-05 | None | None | None | None | N | None | 7.24148E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 33103 |
Ig-156 |
3 | rs1490474972 |
0.0848 | -0.821 | None | N | 0.18 | 0.111 | 0.256283259241 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.08E-06 | 0 |
| T/I | 33598 |
Ig-159 |
3 | rs1272515576 |
0.2052 | 0.009 | 0.093 | N | 0.653 | 0.14 | 0.0401082797425 | gnomAD-2.1.1 | 4.27E-06 | None | None | None | None | N | None | 6.56E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 33598 |
Ig-159 |
3 | rs1272515576 |
0.2052 | 0.009 | 0.093 | N | 0.653 | 0.14 | 0.0401082797425 | gnomAD-4.0.0 | 6.96121E-07 | None | None | None | None | N | None | 3.06542E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 34260 |
Ig-161 |
3 | rs767251580 |
0.9965 | None | 0.76 | N | 0.627 | 0.659 | 0.438593652726 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/L | 34260 |
Ig-161 |
3 | rs767251580 |
0.9965 | None | 0.76 | N | 0.627 | 0.659 | 0.438593652726 | gnomAD-4.0.0 | 6.56978E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46998E-05 | 0 | 0 |
| F/V | 34365 |
Ig-162 |
3 | None | 0.9877 | None | 1.0 | N | 0.766 | 0.797 | 0.887936921424 | gnomAD-4.0.0 | 1.59151E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43291E-05 | 0 |
| I/V | 34944 |
Ig-163 |
3 | rs367770867 |
0.2341 | -1.466 | None | N | 0.236 | 0.12 | None | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| I/V | 34944 |
Ig-163 |
3 | rs367770867 |
0.2341 | -1.466 | None | N | 0.236 | 0.12 | None | gnomAD-4.0.0 | 1.59089E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85753E-06 | 0 | 0 |
| I/N | 35131 |
Ig-164 |
3 | None | 0.9455 | None | 0.997 | N | 0.873 | 0.7 | 0.879508288144 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 35131 |
Ig-164 |
3 | rs779464128 |
0.3167 | -1.315 | 0.58 | D | 0.475 | 0.26 | 0.493695379898 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.55E-05 | 0 |
| I/V | 35131 |
Ig-164 |
3 | rs779464128 |
0.3167 | -1.315 | 0.58 | D | 0.475 | 0.26 | 0.493695379898 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 35131 |
Ig-164 |
3 | rs779464128 |
0.3167 | -1.315 | 0.58 | D | 0.475 | 0.26 | 0.493695379898 | gnomAD-4.0.0 | 3.46993E-05 | None | None | None | None | N | None | 1.33483E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49197E-05 | 0 | 3.20174E-05 |
| I/T | 35288 |
Ig-165 |
3 | rs764713884 |
0.7515 | -2.351 | 0.322 | N | 0.495 | 0.25 | 0.45553875121 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| I/T | 35288 |
Ig-165 |
3 | rs764713884 |
0.7515 | -2.351 | 0.322 | N | 0.495 | 0.25 | 0.45553875121 | gnomAD-4.0.0 | 6.8415E-06 | None | None | None | None | N | None | 2.98704E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09462E-06 | 0 | 0 |
| I/M | 35609 |
Ig-167 |
3 | rs727504540 |
0.1534 | -0.777 | 0.901 | N | 0.701 | 0.23 | 0.414539908741 | gnomAD-2.1.1 | 3.03063E-04 | None | None | None | None | N | None | 0 | 2.34742E-03 | None | 0 | 0 | None | 0 | None | 0 | 7.8E-06 | 1.40174E-04 |
| I/M | 35609 |
Ig-167 |
3 | rs727504540 |
0.1534 | -0.777 | 0.901 | N | 0.701 | 0.23 | 0.414539908741 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 2.6178E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/M | 35609 |
Ig-167 |
3 | rs727504540 |
0.1534 | -0.777 | 0.901 | N | 0.701 | 0.23 | 0.414539908741 | gnomAD-4.0.0 | 6.56804E-05 | None | None | None | None | N | None | 8.0079E-05 | 1.54995E-03 | None | 0 | 0 | None | 0 | 3.28731E-04 | 8.4754E-07 | 0 | 6.40348E-05 |
| I/N | 35609 |
Ig-167 |
3 | None | 0.5466 | None | 0.983 | N | 0.864 | 0.658 | 0.857379640909 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 35609 |
Ig-167 |
3 | rs573508906 |
0.1816 | -1.223 | 0.003 | N | 0.247 | 0.171 | 0.471211772063 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/V | 35609 |
Ig-167 |
3 | rs573508906 |
0.1816 | -1.223 | 0.003 | N | 0.247 | 0.171 | 0.471211772063 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| I/V | 35609 |
Ig-167 |
3 | rs573508906 |
0.1816 | -1.223 | 0.003 | N | 0.247 | 0.171 | 0.471211772063 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| I/V | 35609 |
Ig-167 |
3 | rs573508906 |
0.1816 | -1.223 | 0.003 | N | 0.247 | 0.171 | 0.471211772063 | gnomAD-4.0.0 | 2.0295E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.69704E-05 | 3.39997E-05 |
| F/S | 35704 |
Ig-168 |
3 | rs1422086577 |
0.974 | -2.4 | 0.999 | D | 0.804 | 0.888 | 0.88716126678 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| F/S | 35704 |
Ig-168 |
3 | rs1422086577 |
0.974 | -2.4 | 0.999 | D | 0.804 | 0.888 | 0.88716126678 | gnomAD-4.0.0 | 4.78074E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.58462E-06 | 0 | 0 |
| I/T | 35899 |
Ig-169 |
3 | rs372276487 |
0.9082 | -2.598 | 1.0 | D | 0.794 | 0.688 | None | gnomAD-2.1.1 | 3.01E-05 | None | None | None | -0.311(OBSL1) -0.261(OBSCN) | N | None | 2.09661E-04 | 0 | None | 0 | 0 | None | 3.64E-05 | None | 0 | 1.63E-05 | 0 |
| I/T | 35899 |
Ig-169 |
3 | rs372276487 |
0.9082 | -2.598 | 1.0 | D | 0.794 | 0.688 | None | gnomAD-3.1.2 | 6.57E-05 | None | None | None | -0.311(OBSL1) -0.261(OBSCN) | N | None | 1.93032E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/T | 35899 |
Ig-169 |
3 | rs372276487 |
0.9082 | -2.598 | 1.0 | D | 0.794 | 0.688 | None | gnomAD-4.0.0 | 1.94414E-05 | None | None | None | -0.311(OBSL1) -0.261(OBSCN) | N | None | 1.75794E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 8.54964E-06 | 7.93309E-05 | 1.62639E-05 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.