Structural position:
- Domain Type: Ig
- Aligned Position: 38
- Secondary Structure Element: e
- Secondary Structure Region: β-strand B
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S/N | 30 |
Ig-1 |
25 | rs767153909 |
0.2694 | -0.568 | 0.995 | N | 0.538 | 0.307 | 0.302793454619 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | -0.652(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| S/N | 30 |
Ig-1 |
25 | rs767153909 |
0.2694 | -0.568 | 0.995 | N | 0.538 | 0.307 | 0.302793454619 | gnomAD-4.0.0 | 8.21017E-06 | None | None | None | -0.652(TCAP) | N | None | 1.19489E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29559E-06 | 0 | 1.65618E-05 |
| T/N | 128 |
Ig-2 |
25 | rs769628564 |
0.2401 | -0.827 | 0.982 | N | 0.568 | 0.364 | 0.548737595723 | gnomAD-4.0.0 | 1.36826E-06 | None | None | None | -0.534(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31922E-05 | 0 |
| T/S | 128 |
Ig-2 |
25 | rs769628564 |
0.1778 | -0.953 | 0.064 | N | 0.199 | 0.142 | 0.19670166235 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | -0.391(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/S | 128 |
Ig-2 |
25 | rs769628564 |
0.1778 | -0.953 | 0.064 | N | 0.199 | 0.142 | 0.19670166235 | gnomAD-4.0.0 | 6.8413E-07 | None | None | None | -0.391(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15961E-05 | 0 |
| S/P | 967 |
Ig-3 |
25 | rs768416555 |
0.963 | None | 0.984 | D | 0.533 | 0.428 | 0.515375173082 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| S/P | 967 |
Ig-3 |
25 | rs768416555 |
0.963 | None | 0.984 | D | 0.533 | 0.428 | 0.515375173082 | gnomAD-4.0.0 | 1.59055E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85659E-06 | 0 | 0 |
| V/A | 1481 |
Ig-6 |
25 | rs1252349535 |
0.6277 | -0.989 | 0.999 | N | 0.491 | 0.359 | 0.68405526017 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | I | None | 0 | 0 | None | 1.98728E-04 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/A | 1481 |
Ig-6 |
25 | rs1252349535 |
0.6277 | -0.989 | 0.999 | N | 0.491 | 0.359 | 0.68405526017 | gnomAD-4.0.0 | 4.10463E-06 | None | None | None | None | I | None | 0 | 2.23614E-05 | None | 7.65404E-05 | 0 | None | 0 | 0 | 8.99332E-07 | 0 | 3.31181E-05 |
| T/M | 1580 |
Ig-7 |
25 | rs73973147 |
0.0671 | 0.231 | 0.007 | D | 0.181 | 0.149 | None | gnomAD-2.1.1 | 1.77738E-03 | None | None | None | None | I | None | 1.75066E-02 | 1.04449E-03 | None | 0 | 0 | None | 2.28654E-04 | None | 0 | 9.32E-05 | 1.24723E-03 |
| T/M | 1580 |
Ig-7 |
25 | rs73973147 |
0.0671 | 0.231 | 0.007 | D | 0.181 | 0.149 | None | gnomAD-3.1.2 | 5.1129E-03 | None | None | None | None | I | None | 1.70658E-02 | 3.07592E-03 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 2.05773E-04 | 2.07039E-04 | 3.82044E-03 |
| T/M | 1580 |
Ig-7 |
25 | rs73973147 |
0.0671 | 0.231 | 0.007 | D | 0.181 | 0.149 | None | 1000 genomes | 5.59105E-03 | None | None | None | None | I | None | 1.89E-02 | 4.3E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/M | 1580 |
Ig-7 |
25 | rs73973147 |
0.0671 | 0.231 | 0.007 | D | 0.181 | 0.149 | None | gnomAD-4.0.0 | 1.07864E-03 | None | None | None | None | I | None | 1.80342E-02 | 1.51616E-03 | None | 0 | 4.45831E-05 | None | 0 | 2.30947E-03 | 1.33901E-04 | 3.29374E-04 | 1.48776E-03 |
| I/F | 1729 |
Ig-8 |
27 | rs752183514 |
0.8448 | -0.634 | 1.0 | N | 0.598 | 0.426 | 0.442160178816 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| I/F | 1729 |
Ig-8 |
27 | rs752183514 |
0.8448 | -0.634 | 1.0 | N | 0.598 | 0.426 | 0.442160178816 | gnomAD-4.0.0 | 6.84095E-07 | None | None | None | None | I | None | 2.98757E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 1729 |
Ig-8 |
27 | None | 0.4474 | -0.08 | 0.993 | N | 0.354 | 0.297 | 0.422524665647 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| I/L | 1729 |
Ig-8 |
27 | None | 0.4474 | -0.08 | 0.993 | N | 0.354 | 0.297 | 0.422524665647 | gnomAD-4.0.0 | 2.73638E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59718E-06 | 0 | 0 |
| I/T | 1729 |
Ig-8 |
27 | rs1201228065 |
0.7985 | -0.238 | 1.0 | N | 0.577 | 0.537 | 0.651761151518 | gnomAD-2.1.1 | 1.99E-05 | None | None | None | None | I | None | 0 | 1.44743E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 1729 |
Ig-8 |
27 | rs1201228065 |
0.7985 | -0.238 | 1.0 | N | 0.577 | 0.537 | 0.651761151518 | gnomAD-4.0.0 | 8.20914E-06 | None | None | None | None | I | None | 0 | 8.94654E-05 | None | 0 | 0 | None | 0 | 0 | 6.29507E-06 | 1.15931E-05 | 0 |
| I/V | 1729 |
Ig-8 |
27 | rs752183514 |
0.1724 | None | 0.993 | N | 0.365 | 0.291 | 0.377799810692 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 6.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 1729 |
Ig-8 |
27 | rs752183514 |
0.1724 | None | 0.993 | N | 0.365 | 0.291 | 0.377799810692 | gnomAD-4.0.0 | 5.47276E-06 | None | None | None | None | I | None | 2.98757E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29507E-06 | 0 | 0 |
| T/A | 1865 |
Ig-9 |
25 | rs2092214772 |
0.1725 | None | 0.999 | N | 0.445 | 0.444 | 0.378674557249 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06782E-04 | 0 |
| T/A | 1865 |
Ig-9 |
25 | rs2092214772 |
0.1725 | None | 0.999 | N | 0.445 | 0.444 | 0.378674557249 | gnomAD-4.0.0 | 2.02979E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20491E-06 | 4.69572E-05 | 0 |
| V/L | 2102 |
Ig-10 |
25 | rs767322897 |
0.3453 | -0.532 | 0.577 | N | 0.38 | 0.123 | 0.446715556694 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| V/L | 2102 |
Ig-10 |
25 | rs767322897 |
0.3453 | -0.532 | 0.577 | N | 0.38 | 0.123 | 0.446715556694 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| V/L | 2102 |
Ig-10 |
25 | rs767322897 |
0.3453 | -0.532 | 0.577 | N | 0.38 | 0.123 | 0.446715556694 | gnomAD-4.0.0 | 2.78826E-05 | None | None | None | None | N | None | 0 | 1.66728E-05 | None | 0 | 0 | None | 0 | 0 | 3.47458E-05 | 1.09794E-05 | 3.20113E-05 |
| V/M | 2102 |
Ig-10 |
25 | rs767322897 |
0.2426 | -0.473 | 0.99 | N | 0.533 | 0.19 | 0.54038131941 | gnomAD-2.1.1 | 1.2E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 8.83E-06 | 0 |
| V/M | 2102 |
Ig-10 |
25 | rs767322897 |
0.2426 | -0.473 | 0.99 | N | 0.533 | 0.19 | 0.54038131941 | gnomAD-4.0.0 | 1.09458E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.07918E-05 | 4.63725E-05 | 0 |
| S/P | 2291 |
Ig-12 |
25 | rs1199263112 |
0.8079 | 0.055 | 0.667 | D | 0.47 | 0.4 | 0.444202592202 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.63E-05 | 0 | 0 |
| S/P | 2291 |
Ig-12 |
25 | rs1199263112 |
0.8079 | 0.055 | 0.667 | D | 0.47 | 0.4 | 0.444202592202 | gnomAD-4.0.0 | 1.59084E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88359E-05 | 0 | 0 | 0 | 0 |
| S/A | 2469 |
Ig-14 |
25 | None | 0.2447 | None | 0.997 | D | 0.364 | 0.386 | 0.399596177874 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/L | 2469 |
Ig-14 |
25 | rs2091848374 |
0.4401 | None | 1.0 | D | 0.62 | 0.513 | 0.848577320525 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| S/P | 2469 |
Ig-14 |
25 | rs1483612704 |
0.9507 | None | 1.0 | D | 0.686 | 0.706 | 0.537777371803 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/P | 2469 |
Ig-14 |
25 | rs1483612704 |
0.9507 | None | 1.0 | D | 0.686 | 0.706 | 0.537777371803 | gnomAD-4.0.0 | 6.08959E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.22951E-06 | 0 | 0 |
| S/F | 2557 |
Ig-15 |
25 | None | 0.9713 | None | 1.0 | D | 0.68 | 0.664 | 0.803046222293 | gnomAD-4.0.0 | 6.84132E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99316E-07 | 0 | 0 |
| S/Y | 2557 |
Ig-15 |
25 | None | 0.9276 | None | 1.0 | D | 0.682 | 0.603 | 0.77887435882 | gnomAD-4.0.0 | 6.84132E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.7337E-04 | 0 | 0 | 0 |
| T/A | 2731 |
Ig-17 |
25 | rs2091318582 |
0.3108 | None | 0.76 | D | 0.371 | 0.323 | 0.320256813643 | gnomAD-4.0.0 | 1.59055E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85649E-06 | 0 | 0 |
| T/I | 2731 |
Ig-17 |
25 | None | 0.7433 | None | 0.991 | D | 0.591 | 0.675 | 0.646977041325 | gnomAD-4.0.0 | 1.59057E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85649E-06 | 0 | 0 |
| N/S | 2993 |
Ig-20 |
25 | rs772335542 |
0.2068 | -0.726 | 0.999 | N | 0.493 | 0.418 | 0.244539031024 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.8E-06 | 0 |
| N/S | 2993 |
Ig-20 |
25 | rs772335542 |
0.2068 | -0.726 | 0.999 | N | 0.493 | 0.418 | 0.244539031024 | gnomAD-4.0.0 | 6.84097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.993E-06 | 0 | 0 |
| S/C | 3082 |
Ig-21 |
25 | None | 0.9462 | None | 1.0 | D | 0.674 | 0.545 | 0.729689865996 | gnomAD-4.0.0 | 1.59056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85652E-06 | 0 | 0 |
| N/I | 3171 |
Ig-22 |
25 | rs139992576 |
0.9364 | 0.342 | 1.0 | D | 0.69 | 0.592 | 0.741454687348 | gnomAD-2.1.1 | 1.2E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.8E-05 | None | 0 | 0 | 0 |
| N/I | 3171 |
Ig-22 |
25 | rs139992576 |
0.9364 | 0.342 | 1.0 | D | 0.69 | 0.592 | 0.741454687348 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| N/I | 3171 |
Ig-22 |
25 | rs139992576 |
0.9364 | 0.342 | 1.0 | D | 0.69 | 0.592 | 0.741454687348 | gnomAD-4.0.0 | 3.71727E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.58762E-05 | 0 |
| N/K | 3171 |
Ig-22 |
25 | None | 0.9894 | None | 1.0 | N | 0.649 | 0.284 | 0.178374595973 | gnomAD-4.0.0 | 6.84104E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| N/S | 3171 |
Ig-22 |
25 | rs139992576 |
0.2478 | -0.15 | 0.999 | N | 0.477 | 0.316 | None | gnomAD-2.1.1 | 6.78E-05 | None | None | None | None | N | None | 6.15E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.32535E-04 | 0 |
| N/S | 3171 |
Ig-22 |
25 | rs139992576 |
0.2478 | -0.15 | 0.999 | N | 0.477 | 0.316 | None | gnomAD-3.1.2 | 5.91E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 1.92234E-04 | None | 0 | 0 | 5.88E-05 | 0 | 4.78011E-04 |
| N/S | 3171 |
Ig-22 |
25 | rs139992576 |
0.2478 | -0.15 | 0.999 | N | 0.477 | 0.316 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| N/S | 3171 |
Ig-22 |
25 | rs139992576 |
0.2478 | -0.15 | 0.999 | N | 0.477 | 0.316 | None | gnomAD-4.0.0 | 8.73559E-05 | None | None | None | None | N | None | 3.99712E-05 | 0 | None | 0 | 4.45851E-05 | None | 0 | 1.65017E-04 | 1.1017E-04 | 2.19587E-05 | 4.79985E-05 |
| I/S | 3844 |
Ig-27 |
25 | None | 0.1236 | None | None | N | 0.191 | 0.14 | None | gnomAD-4.0.0 | 6.84224E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| I/T | 3844 |
Ig-27 |
25 | rs1257974534 |
0.0504 | -1.699 | None | N | 0.121 | 0.149 | None | gnomAD-2.1.1 | 7.14E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.81E-06 | 1.40449E-04 |
| I/T | 3844 |
Ig-27 |
25 | rs1257974534 |
0.0504 | -1.699 | None | N | 0.121 | 0.149 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/T | 3844 |
Ig-27 |
25 | rs1257974534 |
0.0504 | -1.699 | None | N | 0.121 | 0.149 | None | gnomAD-4.0.0 | 8.67531E-06 | None | None | None | None | I | None | 1.3328E-05 | 0 | None | 0 | 0 | None | 1.56211E-05 | 0 | 8.47637E-06 | 1.09794E-05 | 1.60056E-05 |
| I/V | 3844 |
Ig-27 |
25 | rs1266364042 |
0.0792 | None | None | N | 0.077 | 0.089 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 3844 |
Ig-27 |
25 | rs1266364042 |
0.0792 | None | None | N | 0.077 | 0.089 | None | gnomAD-4.0.0 | 2.56241E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.24014E-04 | 2.39333E-06 | 0 | 0 |
| T/I | 4630 |
Ig-29 |
25 | rs766878814 |
0.1231 | 0.262 | None | N | 0.169 | 0.09 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/I | 4630 |
Ig-29 |
25 | rs766878814 |
0.1231 | 0.262 | None | N | 0.169 | 0.09 | None | gnomAD-4.0.0 | 1.59128E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85806E-06 | 0 | 0 |
| Q/R | 4724 |
Ig-30 |
25 | rs1553934896 |
0.1072 | None | 0.024 | N | 0.144 | 0.257 | 0.294206760003 | gnomAD-4.0.0 | 1.36865E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79906E-06 | 0 | 0 |
| T/A | 4819 |
Ig-31 |
25 | rs895286829 |
0.0686 | None | 0.005 | N | 0.151 | 0.162 | 0.0482279557977 | gnomAD-4.0.0 | 1.59144E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77423E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/A | 4912 |
Ig-32 |
25 | None | 0.2576 | None | 0.946 | N | 0.613 | 0.424 | 0.459463830659 | gnomAD-4.0.0 | 1.36848E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79893E-06 | 0 | 0 |
| D/G | 4912 |
Ig-32 |
25 | rs2081324623 |
0.2502 | None | 0.716 | N | 0.525 | 0.412 | None | gnomAD-4.0.0 | 2.05271E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6984E-06 | 0 | 0 |
| D/V | 4912 |
Ig-32 |
25 | rs2081324623 |
0.3581 | None | 0.973 | N | 0.717 | 0.583 | 0.644895047373 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 4912 |
Ig-32 |
25 | rs2081324623 |
0.3581 | None | 0.973 | N | 0.717 | 0.583 | 0.644895047373 | gnomAD-4.0.0 | 6.56961E-06 | None | None | None | None | N | None | 0 | 6.5505E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 4912 |
Ig-32 |
25 | rs1177138515 |
0.3458 | None | 0.998 | N | 0.713 | 0.37 | 0.659656470797 | gnomAD-4.0.0 | 4.78961E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29622E-06 | 0 | 0 |
| K/R | 5006 |
Ig-33 |
26 | None | 0.0934 | None | 0.999 | N | 0.537 | 0.336 | 0.362361684037 | gnomAD-4.0.0 | 1.36915E-06 | None | None | None | None | I | None | 2.98829E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99753E-07 | 0 | 0 |
| R/K | 5192 |
Ig-35 |
25 | None | 0.0753 | None | 0.001 | N | 0.119 | 0.131 | 0.181679512989 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| A/S | 5381 |
Ig-37 |
25 | None | 0.1015 | None | 0.079 | N | 0.255 | 0.137 | 0.39162414616 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| Q/K | 5474 |
Ig-38 |
25 | rs1462774944 |
0.0611 | 0.633 | None | N | 0.056 | 0.129 | 0.242825505644 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Q/K | 5474 |
Ig-38 |
25 | rs1462774944 |
0.0611 | 0.633 | None | N | 0.056 | 0.129 | 0.242825505644 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/K | 5474 |
Ig-38 |
25 | rs1462774944 |
0.0611 | 0.633 | None | N | 0.056 | 0.129 | 0.242825505644 | gnomAD-4.0.0 | 1.86017E-06 | None | None | None | None | I | None | 4.00684E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 5474 |
Ig-38 |
25 | None | 0.0608 | None | None | N | 0.091 | 0.103 | 0.183819452728 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/T | 5661 |
Ig-40 |
25 | None | 0.0819 | None | 0.669 | N | 0.286 | 0.141 | 0.250039746154 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/V | 5661 |
Ig-40 |
25 | rs1231169310 |
0.1187 | 0.116 | 0.669 | N | 0.267 | 0.165 | 0.419957187557 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| A/V | 5661 |
Ig-40 |
25 | rs1231169310 |
0.1187 | 0.116 | 0.669 | N | 0.267 | 0.165 | 0.419957187557 | gnomAD-4.0.0 | 3.18296E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.8659E-05 | 0 |
| K/N | 5754 |
Ig-41 |
25 | rs890346105 |
0.4338 | None | 0.968 | N | 0.499 | 0.216 | 0.180583059064 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.93199E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 5754 |
Ig-41 |
25 | rs890346105 |
0.4338 | None | 0.968 | N | 0.499 | 0.216 | 0.180583059064 | gnomAD-4.0.0 | 6.5672E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.93648E-04 | None | 0 | 0 | 0 | 0 | 0 |
| A/S | 5943 |
Ig-43 |
25 | rs1421739163 |
0.098 | None | 0.079 | N | 0.214 | 0.069 | 0.183819452728 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/S | 5943 |
Ig-43 |
25 | rs1421739163 |
0.098 | None | 0.079 | N | 0.214 | 0.069 | 0.183819452728 | gnomAD-4.0.0 | 2.03E-06 | None | None | None | None | N | None | 1.74764E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20493E-06 | 0 | 0 |
| G/C | 6036 |
Ig-44 |
25 | None | 0.1991 | None | 0.013 | N | 0.366 | 0.298 | 0.532696708436 | gnomAD-4.0.0 | 1.59572E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86444E-06 | 0 | 0 |
| G/R | 6036 |
Ig-44 |
25 | rs1308477986 |
0.1652 | -0.297 | 0.006 | N | 0.299 | 0.257 | 0.426787303895 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.05E-06 | 0 |
| G/R | 6036 |
Ig-44 |
25 | rs1308477986 |
0.1652 | -0.297 | 0.006 | N | 0.299 | 0.257 | 0.426787303895 | gnomAD-4.0.0 | 1.59572E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86443E-06 | 0 | 0 |
| G/V | 6036 |
Ig-44 |
25 | None | 0.1529 | None | 0.642 | N | 0.405 | 0.232 | 0.628109234573 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/R | 6130 |
Ig-45 |
26 | rs1379804888 |
0.1025 | None | 0.942 | N | 0.582 | 0.346 | 0.754986483899 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/R | 6130 |
Ig-45 |
26 | rs1379804888 |
0.1025 | None | 0.942 | N | 0.582 | 0.346 | 0.754986483899 | gnomAD-4.0.0 | 8.96994E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.67537E-05 | 0 | 0 |
| T/S | 6130 |
Ig-45 |
26 | rs794727816 |
0.0887 | None | 0.698 | N | 0.391 | 0.218 | 0.218845423259 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 3.66327E-05 |
| T/M | 6223 |
Ig-46 |
25 | rs794727817 |
0.0727 | -0.231 | 0.004 | D | 0.18 | 0.111 | 0.437634105008 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.9E-06 | 0 |
| T/M | 6223 |
Ig-46 |
25 | rs794727817 |
0.0727 | -0.231 | 0.004 | D | 0.18 | 0.111 | 0.437634105008 | gnomAD-4.0.0 | 1.50547E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52042E-05 | None | 0 | 0 | 1.70918E-05 | 2.31889E-05 | 0 |
| A/G | 6316 |
Ig-47 |
25 | None | 0.1506 | None | 0.201 | N | 0.326 | 0.069 | 0.185906805712 | gnomAD-4.0.0 | 1.5959E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86421E-06 | 0 | 0 |
| S/F | 6505 |
Ig-49 |
25 | rs1414011435 |
0.2723 | -0.866 | 0.971 | N | 0.65 | 0.466 | 0.791178816626 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| S/F | 6505 |
Ig-49 |
25 | rs1414011435 |
0.2723 | -0.866 | 0.971 | N | 0.65 | 0.466 | 0.791178816626 | gnomAD-4.0.0 | 1.593E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86038E-06 | 0 | 0 |
| A/S | 6692 |
Ig-51 |
26 | rs757056558 |
0.0743 | None | None | N | 0.066 | 0.082 | 0.141422826196 | gnomAD-4.0.0 | 6.84548E-07 | None | None | None | None | N | None | 2.99133E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 6692 |
Ig-51 |
26 | rs757056558 |
0.0636 | -0.613 | None | N | 0.065 | 0.067 | 0.200317383148 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 9.31E-05 | 8.91E-06 | 0 |
| A/T | 6692 |
Ig-51 |
26 | rs757056558 |
0.0636 | -0.613 | None | N | 0.065 | 0.067 | 0.200317383148 | gnomAD-4.0.0 | 8.21458E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 5.62219E-05 | 0 | 8.09808E-06 | 0 | 0 |
| S/L | 6785 |
Ig-52 |
25 | rs201586695 |
0.0707 | 0.196 | None | N | 0.211 | 0.127 | 0.379707525713 | gnomAD-2.1.1 | 1.22105E-04 | None | None | None | None | N | None | 0 | 2.86517E-04 | None | 0 | 0 | None | 3.3E-05 | None | 0 | 1.72617E-04 | 1.42045E-04 |
| S/L | 6785 |
Ig-52 |
25 | rs201586695 |
0.0707 | 0.196 | None | N | 0.211 | 0.127 | 0.379707525713 | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.32365E-04 | 0 | 0 |
| S/L | 6785 |
Ig-52 |
25 | rs201586695 |
0.0707 | 0.196 | None | N | 0.211 | 0.127 | 0.379707525713 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| S/L | 6785 |
Ig-52 |
25 | rs201586695 |
0.0707 | 0.196 | None | N | 0.211 | 0.127 | 0.379707525713 | gnomAD-4.0.0 | 7.50911E-05 | None | None | None | None | N | None | 0 | 1.8407E-04 | None | 0 | 0 | None | 1.56406E-05 | 0 | 8.65472E-05 | 3.30863E-05 | 6.4156E-05 |
| S/W | 6785 |
Ig-52 |
25 | rs201586695 |
0.24 | -0.85 | 0.924 | N | 0.401 | 0.341 | 0.664306284051 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| E/A | 6878 |
Ig-53 |
25 | rs752107739 |
0.1809 | -0.622 | 0.961 | D | 0.446 | 0.319 | 0.513901218509 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| E/A | 6878 |
Ig-53 |
25 | rs752107739 |
0.1809 | -0.622 | 0.961 | D | 0.446 | 0.319 | 0.513901218509 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| E/A | 6878 |
Ig-53 |
25 | rs752107739 |
0.1809 | -0.622 | 0.961 | D | 0.446 | 0.319 | 0.513901218509 | gnomAD-4.0.0 | 1.66744E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.11419E-05 | 0 | 0 |
| E/Q | 6878 |
Ig-53 |
25 | rs755499713 |
0.133 | -0.085 | 0.961 | N | 0.44 | 0.253 | 0.340273420219 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| E/Q | 6878 |
Ig-53 |
25 | rs755499713 |
0.133 | -0.085 | 0.961 | N | 0.44 | 0.253 | 0.340273420219 | gnomAD-4.0.0 | 1.59421E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86261E-06 | 0 | 0 |
| A/S | 6972 |
Ig-54 |
25 | None | 0.0831 | None | 0.062 | N | 0.12 | 0.203 | 0.185906805712 | gnomAD-4.0.0 | 4.77747E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.58163E-06 | 0 | 0 |
| A/T | 7068 |
Ig-55 |
25 | None | 0.0764 | None | 0.006 | N | 0.234 | 0.087 | 0.216624796971 | gnomAD-4.0.0 | 1.59209E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85956E-06 | 0 | 0 |
| A/V | 7068 |
Ig-55 |
25 | rs2078909515 |
0.1108 | None | 0.193 | N | 0.371 | 0.165 | 0.43126412278 | gnomAD-4.0.0 | 1.59209E-06 | None | None | None | None | I | None | 0 | 2.28906E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 7161 |
Ig-56 |
25 | rs1225806135 |
0.0732 | -0.034 | 0.002 | N | 0.087 | 0.159 | 0.15556083564 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/K | 7161 |
Ig-56 |
25 | rs1225806135 |
0.0732 | -0.034 | 0.002 | N | 0.087 | 0.159 | 0.15556083564 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 7161 |
Ig-56 |
25 | rs1225806135 |
0.0732 | -0.034 | 0.002 | N | 0.087 | 0.159 | 0.15556083564 | gnomAD-4.0.0 | 3.84877E-06 | None | None | None | None | N | None | 1.69302E-05 | 1.69877E-05 | None | 0 | 0 | None | 0 | 0 | 2.39526E-06 | 0 | 0 |
| T/A | 7254 |
Ig-57 |
25 | rs1230527204 |
0.0684 | None | None | N | 0.083 | 0.186 | 0.1749357433 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 7254 |
Ig-57 |
25 | rs1230527204 |
0.0684 | None | None | N | 0.083 | 0.186 | 0.1749357433 | gnomAD-4.0.0 | 3.09882E-06 | None | None | None | None | I | None | 0 | 1.66756E-05 | None | 0 | 0 | None | 0 | 0 | 2.54302E-06 | 1.09801E-05 | 0 |
| A/G | 7347 |
Ig-58 |
25 | rs1359754877 |
0.1351 | -0.608 | 0.005 | N | 0.099 | 0.13 | 0.28058544554 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| A/G | 7347 |
Ig-58 |
25 | rs1359754877 |
0.1351 | -0.608 | 0.005 | N | 0.099 | 0.13 | 0.28058544554 | gnomAD-4.0.0 | 8.21399E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.07963E-05 | 0 | 0 |
| A/S | 7347 |
Ig-58 |
25 | None | 0.0971 | None | 0.022 | N | 0.101 | 0.106 | 0.206339911435 | gnomAD-4.0.0 | 2.05346E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79935E-06 | 0 | 1.65815E-05 |
| A/T | 7347 |
Ig-58 |
25 | rs1553911494 |
0.1206 | None | 0.051 | N | 0.188 | 0.141 | 0.269111216191 | gnomAD-4.0.0 | 6.84487E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99677E-07 | 0 | 0 |
| T/N | 7539 |
Ig-60 |
25 | rs879209114 |
0.1705 | None | 0.826 | N | 0.496 | 0.261 | 0.506613155829 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 7633 |
Ig-61 |
26 | rs1247821028 |
0.2356 | None | 0.051 | N | 0.143 | 0.158 | 0.211220785272 | gnomAD-4.0.0 | 3.60098E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.93752E-06 | 0 | 0 |
| S/L | 7726 |
Ig-62 |
25 | rs17452588 |
0.0843 | 0.102 | 0.031 | N | 0.284 | 0.202 | None | gnomAD-2.1.1 | 7.25853E-03 | None | None | None | None | N | None | 1.32538E-03 | 2.49575E-03 | None | 1.20202E-02 | 5.15E-05 | None | 1.37506E-03 | None | 3.02046E-02 | 7.39956E-03 | 6.07173E-03 |
| S/L | 7726 |
Ig-62 |
25 | rs17452588 |
0.0843 | 0.102 | 0.031 | N | 0.284 | 0.202 | None | gnomAD-3.1.2 | 6.66184E-03 | None | None | None | None | N | None | 1.30365E-03 | 3.99528E-03 | 7.67544E-03 | 1.09636E-02 | 0 | None | 2.93562E-02 | 0 | 7.78056E-03 | 1.45108E-03 | 2.87081E-03 |
| S/L | 7726 |
Ig-62 |
25 | rs17452588 |
0.0843 | 0.102 | 0.031 | N | 0.284 | 0.202 | None | 1000 genomes | 1.99681E-03 | None | None | None | None | N | None | 0 | 2.9E-03 | None | None | 0 | 8E-03 | None | None | None | 0 | None |
| S/L | 7726 |
Ig-62 |
25 | rs17452588 |
0.0843 | 0.102 | 0.031 | N | 0.284 | 0.202 | None | gnomAD-4.0.0 | 7.11628E-03 | None | None | None | None | N | None | 1.16046E-03 | 2.81836E-03 | None | 1.07181E-02 | 2.23125E-05 | None | 2.7213E-02 | 3.3036E-04 | 7.34631E-03 | 1.49421E-03 | 5.70093E-03 |
| E/Q | 7819 |
Ig-63 |
25 | rs201420077 |
0.218 | -0.177 | 0.468 | D | 0.455 | 0.191 | None | gnomAD-2.1.1 | 1.96659E-04 | None | None | None | None | I | None | 0 | 2.83E-05 | None | 0 | 0 | None | 6.54E-05 | None | 7.99E-05 | 3.52676E-04 | 7.03037E-04 |
| E/Q | 7819 |
Ig-63 |
25 | rs201420077 |
0.218 | -0.177 | 0.468 | D | 0.455 | 0.191 | None | gnomAD-3.1.2 | 1.97119E-04 | None | None | None | None | I | None | 0 | 0 | 0 | 2.88184E-04 | 0 | None | 3.76506E-04 | 0 | 3.52837E-04 | 0 | 4.78927E-04 |
| E/Q | 7819 |
Ig-63 |
25 | rs201420077 |
0.218 | -0.177 | 0.468 | D | 0.455 | 0.191 | None | gnomAD-4.0.0 | 2.22478E-04 | None | None | None | None | I | None | 1.33472E-05 | 5.00083E-05 | None | 6.75676E-05 | 2.22836E-05 | None | 2.81241E-04 | 1.64474E-04 | 2.71248E-04 | 5.48992E-05 | 1.28098E-04 |
| T/I | 7913 |
Ig-64 |
25 | None | 0.1624 | None | 0.022 | D | 0.365 | 0.117 | 0.316494231283 | gnomAD-4.0.0 | 6.8427E-07 | None | None | None | None | I | None | 0 | 2.23634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 7913 |
Ig-64 |
25 | None | 0.0786 | None | 0.027 | N | 0.37 | 0.12 | 0.180583059064 | gnomAD-4.0.0 | 6.8427E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99536E-07 | 0 | 0 |
| S/F | 8009 |
Ig-65 |
25 | rs759900757 |
0.1792 | -0.743 | 0.781 | N | 0.636 | 0.428 | 0.758948374077 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/F | 8009 |
Ig-65 |
25 | rs759900757 |
0.1792 | -0.743 | 0.781 | N | 0.636 | 0.428 | 0.758948374077 | gnomAD-4.0.0 | 1.11389E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.71507E-05 | 0 | 3.02407E-05 |
| R/K | 8102 |
Ig-66 |
25 | rs748064860 |
0.0822 | -0.15 | None | N | 0.072 | 0.088 | 0.294206760003 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/K | 8102 |
Ig-66 |
25 | rs748064860 |
0.0822 | -0.15 | None | N | 0.072 | 0.088 | 0.294206760003 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 8102 |
Ig-66 |
25 | rs748064860 |
0.0822 | -0.15 | None | N | 0.072 | 0.088 | 0.294206760003 | gnomAD-4.0.0 | 6.57514E-06 | None | None | None | None | N | None | 2.41441E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 8195 |
Ig-67 |
25 | rs773225442 |
0.0678 | -0.878 | None | N | 0.089 | 0.08 | 0.104622674875 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/A | 8195 |
Ig-67 |
25 | rs773225442 |
0.0678 | -0.878 | None | N | 0.089 | 0.08 | 0.104622674875 | gnomAD-4.0.0 | 1.59143E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8585E-06 | 0 | 0 |
| T/I | 8195 |
Ig-67 |
25 | rs769875081 |
0.1083 | -0.056 | None | N | 0.249 | 0.194 | 0.213573922156 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/I | 8195 |
Ig-67 |
25 | rs769875081 |
0.1083 | -0.056 | None | N | 0.249 | 0.194 | 0.213573922156 | gnomAD-4.0.0 | 6.84241E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99491E-07 | 0 | 0 |
| T/S | 8195 |
Ig-67 |
25 | rs769875081 |
0.0806 | None | None | N | 0.101 | 0.082 | 0.0762999501168 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 8195 |
Ig-67 |
25 | rs769875081 |
0.0806 | None | None | N | 0.101 | 0.082 | 0.0762999501168 | gnomAD-4.0.0 | 6.57194E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/G | 8288 |
Ig-68 |
25 | None | 0.1491 | None | None | N | 0.127 | 0.237 | 0.183819452728 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | I | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 8288 |
Ig-68 |
25 | rs372538009 |
0.108 | None | 0.042 | N | 0.264 | 0.172 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 8288 |
Ig-68 |
25 | rs372538009 |
0.108 | None | 0.042 | N | 0.264 | 0.172 | None | gnomAD-4.0.0 | 2.57995E-06 | None | None | None | None | I | None | 3.38432E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 8384 |
Ig-69 |
25 | None | 0.1127 | None | 0.969 | N | 0.302 | 0.209 | 0.282179105231 | gnomAD-4.0.0 | 4.77702E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57947E-06 | 0 | 0 |
| N/S | 8384 |
Ig-69 |
25 | rs1191447167 |
0.0651 | None | 0.015 | N | 0.123 | 0.101 | 0.165133752707 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| N/S | 8384 |
Ig-69 |
25 | rs1191447167 |
0.0651 | None | 0.015 | N | 0.123 | 0.101 | 0.165133752707 | gnomAD-4.0.0 | 3.18466E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77469E-05 | None | 0 | 0 | 0 | 1.43361E-05 | 0 |
| G/D | 8574 |
Ig-71 |
26 | None | 0.5405 | None | 0.656 | N | 0.391 | 0.153 | 0.340753184043 | gnomAD-4.0.0 | 6.85839E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00922E-07 | 0 | 0 |
| G/R | 8574 |
Ig-71 |
26 | None | 0.442 | None | 0.979 | N | 0.442 | 0.256 | 0.589131389434 | gnomAD-4.0.0 | 6.85979E-07 | None | None | None | None | N | None | 0 | 0 | None | 3.83966E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 8574 |
Ig-71 |
26 | rs752013701 |
0.0824 | -0.454 | 0.028 | N | 0.11 | 0.107 | None | gnomAD-2.1.1 | 1.83E-05 | None | None | None | None | N | None | 8.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.42E-05 | 0 |
| G/S | 8574 |
Ig-71 |
26 | rs752013701 |
0.0824 | -0.454 | 0.028 | N | 0.11 | 0.107 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 9.67E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/S | 8574 |
Ig-71 |
26 | rs752013701 |
0.0824 | -0.454 | 0.028 | N | 0.11 | 0.107 | None | gnomAD-4.0.0 | 5.59085E-06 | None | None | None | None | N | None | 6.68396E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39619E-06 | 0 | 0 |
| Q/E | 8667 |
Ig-72 |
25 | None | 0.0789 | None | 0.01 | N | 0.149 | 0.081 | 0.0986583533028 | gnomAD-4.0.0 | 1.5915E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02407E-05 |
| E/K | 8760 |
Ig-73 |
25 | rs2077161238 |
0.1134 | None | 0.001 | N | 0.108 | 0.182 | 0.229924730088 | gnomAD-4.0.0 | 1.77937E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.33896E-05 | 0 | 0 |
| Y/C | 8950 |
Ig-75 |
25 | rs199557654 |
0.1026 | 0.149 | 0.001 | N | 0.203 | 0.217 | None | gnomAD-2.1.1 | 3.25723E-04 | None | None | None | None | I | None | 1.7113E-04 | 1.77494E-04 | None | 0 | 0 | None | 3.12609E-04 | None | 4.08831E-04 | 4.45478E-04 | 5.84112E-04 |
| Y/C | 8950 |
Ig-75 |
25 | rs199557654 |
0.1026 | 0.149 | 0.001 | N | 0.203 | 0.217 | None | gnomAD-3.1.2 | 2.6951E-04 | None | None | None | None | I | None | 1.20685E-04 | 2.62089E-04 | 0 | 0 | 0 | None | 1.88359E-04 | 0 | 4.11644E-04 | 4.14766E-04 | 0 |
| Y/C | 8950 |
Ig-75 |
25 | rs199557654 |
0.1026 | 0.149 | 0.001 | N | 0.203 | 0.217 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| Y/C | 8950 |
Ig-75 |
25 | rs199557654 |
0.1026 | 0.149 | 0.001 | N | 0.203 | 0.217 | None | gnomAD-4.0.0 | 3.49103E-04 | None | None | None | None | I | None | 6.66951E-05 | 1.6956E-04 | None | 0 | 0 | None | 5.49295E-04 | 1.65235E-04 | 3.94492E-04 | 3.45265E-04 | 2.40902E-04 |
| A/S | 9229 |
Ig-78 |
25 | None | 0.105 | None | 0.124 | N | 0.537 | 0.123 | 0.253205268125 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| S/G | 9325 |
Ig-79 |
25 | None | 0.0959 | None | 0.003 | None | 0.163 | 0.142 | 0.0846915920261 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| S/N | 9325 |
Ig-79 |
25 | rs1454560282 |
0.0903 | None | None | None | 0.046 | 0.171 | 0.0297737177859 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 9325 |
Ig-79 |
25 | rs1454560282 |
0.0903 | None | None | None | 0.046 | 0.171 | 0.0297737177859 | gnomAD-4.0.0 | 6.57315E-06 | None | None | None | None | N | None | 0 | 6.54879E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 9325 |
Ig-79 |
25 | rs1284567095 |
0.2273 | None | None | None | 0.172 | 0.122 | 0.245660935333 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 9325 |
Ig-79 |
25 | rs1284567095 |
0.2273 | None | None | None | 0.172 | 0.122 | 0.245660935333 | gnomAD-4.0.0 | 6.57065E-06 | None | None | None | None | N | None | 2.41266E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 9325 |
Ig-79 |
25 | rs1454560282 |
0.067 | 0.089 | None | None | 0.043 | 0.125 | 0.0297737177859 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| T/M | 9421 |
Ig-80 |
25 | rs375209383 |
0.1554 | 0.173 | 0.161 | None | 0.373 | 0.382 | None | gnomAD-2.1.1 | 8.56E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 4.09878E-04 | None | 1.96066E-04 | None | 7.99E-05 | 6.25E-05 | 0 |
| T/M | 9421 |
Ig-80 |
25 | rs375209383 |
0.1554 | 0.173 | 0.161 | None | 0.373 | 0.382 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 3.85951E-04 | None | 9.43E-05 | 0 | 4.41E-05 | 0 | 0 |
| T/M | 9421 |
Ig-80 |
25 | rs375209383 |
0.1554 | 0.173 | 0.161 | None | 0.373 | 0.382 | None | gnomAD-4.0.0 | 7.18783E-05 | None | None | None | None | I | None | 2.66624E-05 | 0 | None | 0 | 7.57778E-04 | None | 3.1248E-05 | 1.64962E-04 | 4.23793E-05 | 2.52531E-04 | 6.40205E-05 |
| T/S | 9421 |
Ig-80 |
25 | None | 0.1338 | None | 0.006 | None | 0.215 | 0.191 | 0.193865811164 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| A/S | 9518 |
Ig-81 |
26 | None | 0.0954 | None | 0.046 | None | 0.147 | 0.108 | 0.231231049324 | gnomAD-4.0.0 | 1.59125E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85798E-06 | 0 | 0 |
| Q/K | 9614 |
Ig-82 |
25 | None | 0.0842 | None | 0.003 | None | 0.107 | 0.097 | 0.0920862733494 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| G/R | 9722 |
Ig-83 |
25 | rs758659809 |
0.8177 | -0.514 | 1.0 | None | 0.735 | 0.421 | 0.638638447811 | gnomAD-2.1.1 | 7.16E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| G/R | 9722 |
Ig-83 |
25 | rs758659809 |
0.8177 | -0.514 | 1.0 | None | 0.735 | 0.421 | 0.638638447811 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/R | 9722 |
Ig-83 |
25 | rs758659809 |
0.8177 | -0.514 | 1.0 | None | 0.735 | 0.421 | 0.638638447811 | gnomAD-4.0.0 | 7.45356E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.0194E-05 | 0 | 0 |
| S/F | 10013 |
Ig-85 |
25 | None | 0.9002 | None | 0.987 | None | 0.598 | 0.511 | 0.710634673768 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 10013 |
Ig-85 |
25 | None | 0.9413 | None | 0.999 | None | 0.611 | 0.534 | 0.570372710236 | gnomAD-4.0.0 | 1.59086E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85749E-06 | 0 | 0 |
| N/K | 13805 |
Ig-88 |
26 | rs753262730 |
0.9827 | -0.071 | 0.961 | N | 0.488 | 0.139 | 0.0846915920261 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| N/K | 13805 |
Ig-88 |
26 | rs753262730 |
0.9827 | -0.071 | 0.961 | N | 0.488 | 0.139 | 0.0846915920261 | gnomAD-4.0.0 | 1.5932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86102E-06 | 0 | 0 |
| A/G | 13898 |
Ig-89 |
23 | None | 0.2796 | None | 0.181 | N | 0.264 | 0.09 | 0.326074293725 | gnomAD-4.0.0 | 1.6384E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.82056E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 14166 |
Ig-92 |
25 | None | 0.523 | None | 0.973 | D | 0.324 | 0.392 | 0.392702134506 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 14255 |
Ig-93 |
25 | rs368433387 |
0.5292 | -0.383 | 0.058 | D | 0.141 | 0.253 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/N | 14255 |
Ig-93 |
25 | rs368433387 |
0.5292 | -0.383 | 0.058 | D | 0.141 | 0.253 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/N | 14255 |
Ig-93 |
25 | rs368433387 |
0.5292 | -0.383 | 0.058 | D | 0.141 | 0.253 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| S/N | 14255 |
Ig-93 |
25 | rs368433387 |
0.5292 | -0.383 | 0.058 | D | 0.141 | 0.253 | None | gnomAD-4.0.0 | 5.07429E-06 | None | None | None | None | N | None | 6.9752E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.39997E-05 |
| S/F | 14432 |
Ig-95 |
25 | rs1204829254 |
0.9419 | -0.906 | 1.0 | D | 0.707 | 0.454 | 0.67357427822 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/F | 14432 |
Ig-95 |
25 | rs1204829254 |
0.9419 | -0.906 | 1.0 | D | 0.707 | 0.454 | 0.67357427822 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 14432 |
Ig-95 |
25 | rs1204829254 |
0.9419 | -0.906 | 1.0 | D | 0.707 | 0.454 | 0.67357427822 | gnomAD-4.0.0 | 6.57981E-06 | None | None | None | None | N | None | 2.41569E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 14521 |
Ig-96 |
25 | None | 0.5732 | None | 0.997 | D | 0.382 | 0.497 | 0.510524285738 | gnomAD-4.0.0 | 6.8753E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.177E-05 | 0 |
| S/C | 14521 |
Ig-96 |
25 | rs1326450347 |
0.7854 | None | 1.0 | D | 0.699 | 0.559 | 0.666426553935 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/C | 14521 |
Ig-96 |
25 | rs1326450347 |
0.7854 | None | 1.0 | D | 0.699 | 0.559 | 0.666426553935 | gnomAD-4.0.0 | 6.57903E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47106E-05 | 0 | 0 |
| S/F | 14521 |
Ig-96 |
25 | None | 0.963 | None | 1.0 | D | 0.741 | 0.535 | 0.648203075438 | gnomAD-4.0.0 | 1.37494E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80453E-06 | 0 | 0 |
| S/P | 14521 |
Ig-96 |
25 | rs1161247099 |
0.9726 | -0.127 | 1.0 | D | 0.689 | 0.626 | 0.593315388404 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/P | 14521 |
Ig-96 |
25 | rs1161247099 |
0.9726 | -0.127 | 1.0 | D | 0.689 | 0.626 | 0.593315388404 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| S/P | 14521 |
Ig-96 |
25 | rs1161247099 |
0.9726 | -0.127 | 1.0 | D | 0.689 | 0.626 | 0.593315388404 | gnomAD-4.0.0 | 3.73471E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.25082E-06 | 0 | 1.60767E-05 |
| S/R | 14610 |
Ig-97 |
25 | None | 0.9673 | None | 1.0 | D | 0.697 | 0.58 | 0.566666267248 | gnomAD-4.0.0 | 1.36913E-06 | None | None | None | None | N | None | 2.98954E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99666E-07 | 0 | 0 |
| S/C | 14699 |
Ig-98 |
25 | rs1293270234 |
0.7476 | -0.246 | 1.0 | D | 0.677 | 0.465 | 0.340032825777 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 1.65893E-04 |
| S/C | 14699 |
Ig-98 |
25 | rs1293270234 |
0.7476 | -0.246 | 1.0 | D | 0.677 | 0.465 | 0.340032825777 | gnomAD-4.0.0 | 4.77686E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.58099E-06 | 0 | 0 |
| S/F | 14788 |
Ig-99 |
24 | rs2059491089 |
0.939 | None | 0.999 | D | 0.607 | 0.498 | 0.814208784794 | gnomAD-4.0.0 | 3.18642E-06 | None | None | None | None | N | None | 0 | 2.28812E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02828E-05 |
| S/P | 14788 |
Ig-99 |
24 | rs761110890 |
0.9445 | 0.095 | 0.999 | D | 0.575 | 0.6 | 0.626983275866 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| S/P | 14788 |
Ig-99 |
24 | rs761110890 |
0.9445 | 0.095 | 0.999 | D | 0.575 | 0.6 | 0.626983275866 | gnomAD-4.0.0 | 6.84569E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99807E-07 | 0 | 0 |
| S/T | 14788 |
Ig-99 |
24 | None | 0.2413 | None | 0.543 | N | 0.269 | 0.246 | 0.379707525713 | gnomAD-4.0.0 | 6.84569E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99807E-07 | 0 | 0 |
| S/C | 14966 |
Ig-101 |
25 | rs1022414957 |
0.6146 | None | 1.0 | D | 0.704 | 0.583 | 0.758948374077 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/C | 14966 |
Ig-101 |
25 | rs1022414957 |
0.6146 | None | 1.0 | D | 0.704 | 0.583 | 0.758948374077 | gnomAD-4.0.0 | 6.59152E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47406E-05 | 0 | 0 |
| S/P | 14966 |
Ig-101 |
25 | rs760963803 |
0.8014 | -0.047 | 1.0 | D | 0.702 | 0.615 | 0.541962755691 | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.45E-05 | None | 0 | 0 | 0 |
| S/P | 14966 |
Ig-101 |
25 | rs760963803 |
0.8014 | -0.047 | 1.0 | D | 0.702 | 0.615 | 0.541962755691 | gnomAD-4.0.0 | 1.60872E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.46319E-05 | 0 |
| S/Y | 14966 |
Ig-101 |
25 | None | 0.7371 | None | 1.0 | D | 0.767 | 0.577 | 0.863293222284 | gnomAD-4.0.0 | 6.87597E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02247E-07 | 0 | 0 |
| S/P | 15055 |
Ig-102 |
25 | None | 0.9284 | None | 1.0 | D | 0.693 | 0.611 | 0.633466640759 | gnomAD-4.0.0 | 1.36951E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79989E-06 | 0 | 0 |
| S/T | 15055 |
Ig-102 |
25 | None | 0.1807 | None | 0.999 | D | 0.397 | 0.408 | 0.505335117028 | gnomAD-4.0.0 | 6.84754E-07 | None | None | None | None | N | None | 2.99491E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/D | 15232 |
Ig-104 |
25 | None | 0.6047 | None | 0.999 | N | 0.529 | 0.495 | 0.542587012665 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| N/K | 15326 |
Ig-105 |
25 | None | 0.9819 | None | 1.0 | N | 0.657 | 0.341 | 0.256793551483 | gnomAD-4.0.0 | 6.84882E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65898E-05 |
| N/S | 15326 |
Ig-105 |
25 | rs2058104840 |
0.2746 | None | 0.999 | N | 0.491 | 0.452 | 0.276898752692 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/S | 15326 |
Ig-105 |
25 | rs2058104840 |
0.2746 | None | 0.999 | N | 0.491 | 0.452 | 0.276898752692 | gnomAD-4.0.0 | 6.58059E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4728E-05 | 0 | 0 |
| N/S | 15504 |
Ig-107 |
25 | rs1184631064 |
0.184 | 0.004 | 0.904 | N | 0.398 | 0.361 | 0.193865811164 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/S | 15504 |
Ig-107 |
25 | rs1184631064 |
0.184 | 0.004 | 0.904 | N | 0.398 | 0.361 | 0.193865811164 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/S | 15504 |
Ig-107 |
25 | rs1184631064 |
0.184 | 0.004 | 0.904 | N | 0.398 | 0.361 | 0.193865811164 | gnomAD-4.0.0 | 6.82305E-06 | None | None | None | None | N | None | 1.33711E-05 | 6.68181E-05 | None | 0 | 0 | None | 0 | 0 | 5.08943E-06 | 0 | 0 |
| T/A | 15987 |
Ig-109 |
20 | None | 0.097 | None | 0.981 | D | 0.478 | 0.413 | 0.499921029546 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 3.66327E-05 |
| T/I | 15987 |
Ig-109 |
20 | rs1429436042 |
0.2366 | 0.114 | 0.999 | D | 0.671 | 0.502 | 0.658336924587 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | I | None | 8.28E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 15987 |
Ig-109 |
20 | rs1429436042 |
0.2366 | 0.114 | 0.999 | D | 0.671 | 0.502 | 0.658336924587 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 15987 |
Ig-109 |
20 | rs1429436042 |
0.2366 | 0.114 | 0.999 | D | 0.671 | 0.502 | 0.658336924587 | gnomAD-4.0.0 | 3.10075E-06 | None | None | None | None | I | None | 6.68682E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 16979 |
Ig-111 |
25 | rs1559776809 |
0.5334 | None | 0.99 | N | 0.544 | 0.433 | 0.506793516358 | gnomAD-4.0.0 | 3.18681E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.57693E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 16979 |
Ig-111 |
25 | None | 0.136 | None | 0.4 | N | 0.164 | 0.117 | 0.285698343383 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| R/S | 16979 |
Ig-111 |
25 | None | 0.6386 | None | 0.98 | N | 0.589 | 0.37 | 0.314417295294 | gnomAD-4.0.0 | 6.84606E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65832E-05 |
| S/A | 17272 |
Ig-112 |
22 | rs1308609622 |
0.1177 | -0.339 | 0.656 | N | 0.371 | 0.24 | 0.298745278005 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| S/A | 17272 |
Ig-112 |
22 | rs1308609622 |
0.1177 | -0.339 | 0.656 | N | 0.371 | 0.24 | 0.298745278005 | gnomAD-4.0.0 | 6.16231E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.04457E-04 | 0 |
| T/I | 17991 |
Ig-114 |
24 | None | 0.1958 | None | 0.978 | N | 0.579 | 0.346 | 0.430239905395 | gnomAD-4.0.0 | 2.73955E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.5364E-05 | None | 0 | 0 | 9.00004E-07 | 2.32105E-05 | 0 |
| K/E | 18403 |
Ig-115 |
22 | None | 0.3009 | None | 0.722 | N | 0.429 | 0.24 | 0.305410167561 | gnomAD-4.0.0 | 1.59329E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02847E-05 |
| R/G | 20794 |
Ig-122 |
26 | rs1339109963 |
0.4171 | -0.433 | 1.0 | N | 0.603 | 0.533 | 0.51469891142 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| R/G | 20794 |
Ig-122 |
26 | rs1339109963 |
0.4171 | -0.433 | 1.0 | N | 0.603 | 0.533 | 0.51469891142 | gnomAD-4.0.0 | 1.59233E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02608E-05 |
| R/T | 20794 |
Ig-122 |
26 | rs765092290 |
0.2878 | 0.09 | 1.0 | N | 0.672 | 0.378 | 0.42538462244 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 8.72E-05 | None | 0 | 0 | None | 9.82E-05 | None | 0 | 0 | 0 |
| R/T | 20794 |
Ig-122 |
26 | rs765092290 |
0.2878 | 0.09 | 1.0 | N | 0.672 | 0.378 | 0.42538462244 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06954E-04 | 0 |
| R/T | 20794 |
Ig-122 |
26 | rs765092290 |
0.2878 | 0.09 | 1.0 | N | 0.672 | 0.378 | 0.42538462244 | gnomAD-4.0.0 | 8.97399E-06 | None | None | None | None | N | None | 0 | 5.08906E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 5.36337E-05 | 0 |
| Y/C | 21491 |
Ig-124 |
23 | rs757450750 |
0.1776 | -0.054 | 0.999 | N | 0.343 | 0.296 | None | gnomAD-2.1.1 | 2.86E-05 | None | None | None | None | N | None | 0 | 1.98278E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.40607E-04 |
| Y/C | 21491 |
Ig-124 |
23 | rs757450750 |
0.1776 | -0.054 | 0.999 | N | 0.343 | 0.296 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Y/C | 21491 |
Ig-124 |
23 | rs757450750 |
0.1776 | -0.054 | 0.999 | N | 0.343 | 0.296 | None | gnomAD-4.0.0 | 1.2821E-05 | None | None | None | None | N | None | 0 | 1.35658E-04 | None | 0 | 0 | None | 0 | 0 | 4.79044E-06 | 0 | 0 |
| F/L | 21888 |
Ig-125 |
23 | rs1230631157 |
0.8693 | -0.499 | 0.007 | N | 0.132 | 0.276 | 0.235664433957 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| F/L | 21888 |
Ig-125 |
23 | rs1230631157 |
0.8693 | -0.499 | 0.007 | N | 0.132 | 0.276 | 0.235664433957 | gnomAD-4.0.0 | 6.16279E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09932E-06 | 0 | 0 |
| F/V | 21888 |
Ig-125 |
23 | None | 0.3241 | None | 0.521 | N | 0.389 | 0.38 | 0.61789491966 | gnomAD-4.0.0 | 6.84754E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73732E-04 | 0 | 0 | 0 |
| L/P | 22972 |
Ig-128 |
23 | rs2046677771 |
0.7352 | None | 0.484 | N | 0.421 | 0.322 | 0.74037354781 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.96928E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 22972 |
Ig-128 |
23 | rs2046677771 |
0.7352 | None | 0.484 | N | 0.421 | 0.322 | 0.74037354781 | gnomAD-4.0.0 | 1.97392E-05 | None | None | None | None | N | None | 0 | 1.96928E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 23369 |
Ig-129 |
25 | rs1277463353 |
0.3836 | None | 0.822 | N | 0.541 | 0.179 | 0.332386209738 | gnomAD-4.0.0 | 1.59238E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86071E-06 | 0 | 0 |
| L/F | 23658 |
Ig-130 |
22 | None | 0.1156 | None | 1.0 | N | 0.657 | 0.25 | 0.658123265804 | gnomAD-4.0.0 | 1.59389E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43538E-05 | 0 |
| S/L | 24054 |
Ig-131 |
26 | None | 0.0736 | None | 0.101 | D | 0.293 | 0.285 | 0.587417723555 | gnomAD-4.0.0 | 1.36877E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79918E-06 | 0 | 0 |
| I/T | 24740 |
Ig-133 |
25 | rs773198304 |
0.0646 | -1.314 | None | N | 0.171 | 0.107 | 0.453772157364 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| I/T | 24740 |
Ig-133 |
25 | rs773198304 |
0.0646 | -1.314 | None | N | 0.171 | 0.107 | 0.453772157364 | gnomAD-4.0.0 | 3.18458E-06 | None | None | None | None | N | None | 0 | 2.28749E-05 | None | 0 | 2.78118E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Y/N | 25136 |
Ig-134 |
26 | None | 0.0993 | None | 0.029 | N | 0.391 | 0.141 | 0.279370189704 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| S/P | 25822 |
Ig-136 |
25 | None | 0.7723 | None | 0.896 | N | 0.354 | 0.443 | 0.32082282376 | gnomAD-4.0.0 | 1.59211E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85956E-06 | 0 | 0 |
| K/R | 26617 |
Ig-138 |
24 | None | 0.0642 | None | 0.046 | N | 0.229 | 0.151 | 0.247322355667 | gnomAD-4.0.0 | 3.60103E-06 | None | None | None | None | N | None | 1.26695E-04 | 0 | None | 0 | 0 | None | 0 | 6.17284E-04 | 0 | 0 | 0 |
| I/M | 26904 |
Ig-139 |
25 | rs773395582 |
0.0782 | -0.251 | 0.81 | N | 0.351 | 0.134 | 0.531873083431 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.44E-05 | 0 |
| I/M | 26904 |
Ig-139 |
25 | rs773395582 |
0.0782 | -0.251 | 0.81 | N | 0.351 | 0.134 | 0.531873083431 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/M | 26904 |
Ig-139 |
25 | rs773395582 |
0.0782 | -0.251 | 0.81 | N | 0.351 | 0.134 | 0.531873083431 | gnomAD-4.0.0 | 3.65691E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.00149E-05 | 0 | 0 |
| I/T | 26904 |
Ig-139 |
25 | rs991499250 |
0.0703 | None | 0.549 | N | 0.26 | 0.257 | 0.638307893888 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 26904 |
Ig-139 |
25 | rs991499250 |
0.0703 | None | 0.549 | N | 0.26 | 0.257 | 0.638307893888 | gnomAD-4.0.0 | 6.57367E-06 | None | None | None | None | I | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 27300 |
Ig-140 |
23 | rs372530032 |
0.0987 | -0.025 | 0.877 | D | 0.238 | 0.352 | None | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | I | None | 0 | 5.8E-05 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 2.68E-05 | 0 |
| R/C | 27300 |
Ig-140 |
23 | rs372530032 |
0.0987 | -0.025 | 0.877 | D | 0.238 | 0.352 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/C | 27300 |
Ig-140 |
23 | rs372530032 |
0.0987 | -0.025 | 0.877 | D | 0.238 | 0.352 | None | gnomAD-4.0.0 | 1.79772E-05 | None | None | None | None | I | None | 0 | 5.00117E-05 | None | 0 | 0 | None | 0 | 0 | 1.94956E-05 | 2.19587E-05 | 1.60123E-05 |
| R/H | 27300 |
Ig-140 |
23 | rs55850344 |
0.0633 | -0.735 | None | N | 0.081 | 0.069 | None | gnomAD-2.1.1 | 3.58069E-04 | None | None | None | None | I | None | 2.8928E-04 | 3.11156E-04 | None | 0 | 1.02564E-04 | None | 4.24837E-04 | None | 3.64225E-04 | 4.47122E-04 | 1.40568E-04 |
| R/H | 27300 |
Ig-140 |
23 | rs55850344 |
0.0633 | -0.735 | None | N | 0.081 | 0.069 | None | gnomAD-3.1.2 | 3.48409E-04 | None | None | None | None | I | None | 2.89659E-04 | 2.6202E-04 | 0 | 0 | 0 | None | 9.42E-05 | 0 | 5.29303E-04 | 0 | 0 |
| R/H | 27300 |
Ig-140 |
23 | rs55850344 |
0.0633 | -0.735 | None | N | 0.081 | 0.069 | None | gnomAD-4.0.0 | 4.20878E-04 | None | None | None | None | I | None | 3.33244E-04 | 2.83296E-04 | None | 3.37906E-05 | 0 | None | 3.62113E-04 | 6.60066E-04 | 4.67889E-04 | 3.73282E-04 | 3.68141E-04 |
| R/L | 27300 |
Ig-140 |
23 | None | 0.1458 | None | 0.058 | N | 0.202 | 0.16 | 0.346085882481 | gnomAD-4.0.0 | 6.84436E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99473E-07 | 0 | 0 |
| K/R | 27987 |
Ig-142 |
25 | None | 0.0654 | None | 0.001 | N | 0.136 | 0.091 | 0.329282125956 | gnomAD-4.0.0 | 1.5929E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02718E-05 |
| R/Q | 28779 |
Ig-144 |
25 | rs763175453 |
0.1054 | 0.023 | 0.998 | N | 0.492 | 0.306 | 0.21737058555 | gnomAD-2.1.1 | 3.28E-05 | None | None | None | None | I | None | 1.29316E-04 | 2.92E-05 | None | 0 | 0 | None | 3.35E-05 | None | 0 | 2.7E-05 | 1.69033E-04 |
| R/Q | 28779 |
Ig-144 |
25 | rs763175453 |
0.1054 | 0.023 | 0.998 | N | 0.492 | 0.306 | 0.21737058555 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/Q | 28779 |
Ig-144 |
25 | rs763175453 |
0.1054 | 0.023 | 0.998 | N | 0.492 | 0.306 | 0.21737058555 | gnomAD-4.0.0 | 2.98549E-05 | None | None | None | None | I | None | 4.00877E-05 | 1.67499E-05 | None | 0 | 0 | None | 0 | 0 | 2.80159E-05 | 1.10627E-04 | 1.60643E-05 |
| S/P | 29069 |
Ig-145 |
25 | None | 0.8816 | None | 0.794 | N | 0.369 | 0.464 | 0.304108284078 | gnomAD-4.0.0 | 1.59128E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85789E-06 | 0 | 0 |
| S/F | 29465 |
Ig-146 |
22 | rs146181116 |
0.1657 | -0.835 | 0.988 | D | 0.349 | 0.331 | None | gnomAD-2.1.1 | 3.13962E-03 | None | None | None | None | I | None | 5.78799E-04 | 1.2732E-03 | None | 2.03331E-03 | 0 | None | 1.96117E-04 | None | 6.31545E-03 | 4.7872E-03 | 3.23306E-03 |
| S/F | 29465 |
Ig-146 |
22 | rs146181116 |
0.1657 | -0.835 | 0.988 | D | 0.349 | 0.331 | None | gnomAD-3.1.2 | 3.25363E-03 | None | None | None | None | I | None | 7.72201E-04 | 1.44092E-03 | 0 | 1.15274E-03 | 0 | None | 5.18672E-03 | 0 | 5.55735E-03 | 2.07211E-04 | 1.43541E-03 |
| S/F | 29465 |
Ig-146 |
22 | rs146181116 |
0.1657 | -0.835 | 0.988 | D | 0.349 | 0.331 | None | 1000 genomes | 1.79712E-03 | None | None | None | None | I | None | 0 | 1.4E-03 | None | None | 0 | 7E-03 | None | None | None | 1E-03 | None |
| S/F | 29465 |
Ig-146 |
22 | rs146181116 |
0.1657 | -0.835 | 0.988 | D | 0.349 | 0.331 | None | gnomAD-4.0.0 | 3.75516E-03 | None | None | None | None | I | None | 5.9968E-04 | 1.36648E-03 | None | 1.92555E-03 | 0 | None | 6.75E-03 | 1.65071E-04 | 4.46768E-03 | 2.08626E-04 | 2.44925E-03 |
| K/E | 29864 |
Ig-147 |
23 | rs770839822 |
0.5455 | 0.372 | 0.999 | N | 0.605 | 0.406 | 0.405012372841 | gnomAD-2.1.1 | 8.21E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.11371E-04 | None | 0 | None | 0 | 0 | 0 |
| K/E | 29864 |
Ig-147 |
23 | rs770839822 |
0.5455 | 0.372 | 0.999 | N | 0.605 | 0.406 | 0.405012372841 | gnomAD-4.0.0 | 1.76963E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77346E-04 | None | 0 | 0 | 0 | 0 | 3.02883E-05 |
| K/E | 30156 |
Ig-148 |
25 | rs762340648 |
0.3178 | 0.621 | 0.999 | N | 0.583 | 0.402 | 0.406531046227 | gnomAD-2.1.1 | 4.11E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.05E-06 | 0 |
| K/E | 30156 |
Ig-148 |
25 | rs762340648 |
0.3178 | 0.621 | 0.999 | N | 0.583 | 0.402 | 0.406531046227 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/E | 30156 |
Ig-148 |
25 | rs762340648 |
0.3178 | 0.621 | 0.999 | N | 0.583 | 0.402 | 0.406531046227 | gnomAD-4.0.0 | 2.60206E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.8846E-06 | 0 | 0 |
| Q/K | 30551 |
Ig-149 |
20 | None | 0.0996 | None | None | N | 0.113 | 0.096 | 0.149567049428 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/R | 30551 |
Ig-149 |
20 | rs775297990 |
0.1091 | 0.326 | None | N | 0.142 | 0.14 | 0.0986583533028 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 1.65728E-04 |
| Q/R | 30551 |
Ig-149 |
20 | rs775297990 |
0.1091 | 0.326 | None | N | 0.142 | 0.14 | 0.0986583533028 | gnomAD-4.0.0 | 2.73687E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79899E-06 | 0 | 3.3129E-05 |
| Q/H | 30950 |
Ig-150 |
24 | None | 0.118 | None | 0.295 | N | 0.199 | 0.081 | 0.216624796971 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| S/G | 31240 |
Ig-151 |
23 | rs757914126 |
0.1284 | -0.37 | 0.001 | D | 0.199 | 0.194 | 0.285316908763 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/G | 31240 |
Ig-151 |
23 | rs757914126 |
0.1284 | -0.37 | 0.001 | D | 0.199 | 0.194 | 0.285316908763 | gnomAD-4.0.0 | 1.59116E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| S/R | 31240 |
Ig-151 |
23 | None | 0.4385 | None | 0.497 | N | 0.501 | 0.299 | 0.406257615169 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/C | 31640 |
Ig-152 |
20 | rs773967663 |
0.2128 | None | 1.0 | N | 0.679 | 0.458 | 0.639984247256 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| G/C | 31640 |
Ig-152 |
20 | rs773967663 |
0.2128 | None | 1.0 | N | 0.679 | 0.458 | 0.639984247256 | gnomAD-4.0.0 | 6.84222E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99486E-07 | 0 | 0 |
| G/D | 31640 |
Ig-152 |
20 | rs1697151144 |
0.4422 | None | 1.0 | N | 0.67 | 0.471 | 0.401753679984 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/R | 31640 |
Ig-152 |
20 | rs773967663 |
0.4531 | None | 1.0 | N | 0.657 | 0.493 | 0.546087423956 | gnomAD-4.0.0 | 1.36844E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.04083E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 31640 |
Ig-152 |
20 | None | 0.1001 | -0.423 | 1.0 | N | 0.653 | 0.413 | 0.337378238328 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| G/S | 31640 |
Ig-152 |
20 | None | 0.1001 | -0.423 | 1.0 | N | 0.653 | 0.413 | 0.337378238328 | gnomAD-4.0.0 | 6.158E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09537E-06 | 0 | 0 |
| G/V | 31640 |
Ig-152 |
20 | rs1697151144 |
0.2514 | None | 1.0 | N | 0.703 | 0.442 | 0.554156219314 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 31640 |
Ig-152 |
20 | rs1697151144 |
0.2514 | None | 1.0 | N | 0.703 | 0.442 | 0.554156219314 | gnomAD-4.0.0 | 6.57445E-06 | None | None | None | None | I | None | 0 | 6.55308E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 32039 |
Ig-153 |
23 | None | 0.0673 | None | 0.079 | N | 0.161 | 0.145 | 0.218112801441 | gnomAD-4.0.0 | 1.59154E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85883E-06 | 0 | 0 |
| K/R | 32729 |
Ig-155 |
22 | rs1368497531 |
0.0859 | 0.099 | 0.018 | N | 0.254 | 0.115 | 0.307332253619 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| K/R | 32729 |
Ig-155 |
22 | rs1368497531 |
0.0859 | 0.099 | 0.018 | N | 0.254 | 0.115 | 0.307332253619 | gnomAD-4.0.0 | 1.3684E-06 | None | None | None | None | I | None | 0 | 2.23624E-05 | None | 0 | 2.5194E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/T | 32729 |
Ig-155 |
22 | rs1368497531 |
0.2502 | None | 0.722 | N | 0.507 | 0.284 | 0.29132392195 | gnomAD-4.0.0 | 1.3684E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79895E-06 | 0 | 0 |
| V/L | 33125 |
Ig-156 |
25 | rs1692289481 |
0.1686 | None | 0.003 | N | 0.139 | 0.176 | 0.626300511109 | gnomAD-4.0.0 | 3.18323E-06 | None | None | None | None | N | None | 0 | 4.57561E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 33221 |
Ig-157 |
19 | rs938263270 |
0.2282 | None | 0.983 | N | 0.346 | 0.331 | 0.609990207021 | gnomAD-4.0.0 | 6.84242E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99486E-07 | 0 | 0 |
| I/T | 33221 |
Ig-157 |
19 | rs1306714947 |
0.2147 | None | 1.0 | N | 0.547 | 0.489 | 0.710785509443 | gnomAD-4.0.0 | 4.78971E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.00801E-04 | None | 0 | 0 | 1.79898E-06 | 1.15937E-05 | 0 |
| I/V | 33221 |
Ig-157 |
19 | rs938263270 |
0.1044 | -1.589 | 0.987 | N | 0.343 | 0.256 | 0.690830541769 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/V | 33221 |
Ig-157 |
19 | rs938263270 |
0.1044 | -1.589 | 0.987 | N | 0.343 | 0.256 | 0.690830541769 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 33221 |
Ig-157 |
19 | rs938263270 |
0.1044 | -1.589 | 0.987 | N | 0.343 | 0.256 | 0.690830541769 | gnomAD-4.0.0 | 3.71827E-06 | None | None | None | None | N | None | 8.00918E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 33520 |
Ig-158 |
25 | rs879185434 |
0.1441 | None | 0.014 | N | 0.29 | 0.153 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 33520 |
Ig-158 |
25 | rs879185434 |
0.1441 | None | 0.014 | N | 0.29 | 0.153 | None | gnomAD-4.0.0 | 1.97106E-05 | None | None | None | None | N | None | 7.23624E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 33520 |
Ig-158 |
25 | rs1691426177 |
0.2181 | None | 0.432 | N | 0.361 | 0.171 | 0.31501682445 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 33520 |
Ig-158 |
25 | rs1691426177 |
0.2181 | None | 0.432 | N | 0.361 | 0.171 | 0.31501682445 | gnomAD-4.0.0 | 6.57212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47007E-05 | 0 | 0 |
| T/S | 33520 |
Ig-158 |
25 | None | 0.1526 | None | 0.066 | N | 0.321 | 0.153 | 0.203808441222 | gnomAD-4.0.0 | 1.59201E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85935E-06 | 0 | 0 |
| S/T | 33620 |
Ig-159 |
25 | rs369261182 |
0.1078 | -0.346 | 0.217 | N | 0.252 | 0.078 | None | gnomAD-2.1.1 | 2.14E-05 | None | None | None | None | N | None | 4.14E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 3.13E-05 | 0 |
| S/T | 33620 |
Ig-159 |
25 | rs369261182 |
0.1078 | -0.346 | 0.217 | N | 0.252 | 0.078 | None | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| S/T | 33620 |
Ig-159 |
25 | rs369261182 |
0.1078 | -0.346 | 0.217 | N | 0.252 | 0.078 | None | gnomAD-4.0.0 | 6.26131E-05 | None | None | None | None | N | None | 2.67666E-05 | 1.66811E-05 | None | 0 | 0 | None | 0 | 0 | 8.13751E-05 | 0 | 3.20256E-05 |
| T/N | 34282 |
Ig-161 |
25 | rs369595031 |
0.6197 | -0.65 | 0.991 | D | 0.542 | 0.428 | None | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/N | 34282 |
Ig-161 |
25 | rs369595031 |
0.6197 | -0.65 | 0.991 | D | 0.542 | 0.428 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 34282 |
Ig-161 |
25 | rs369595031 |
0.6197 | -0.65 | 0.991 | D | 0.542 | 0.428 | None | gnomAD-4.0.0 | 6.56961E-06 | None | None | None | None | N | None | 2.41196E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 34387 |
Ig-162 |
25 | None | 0.9783 | None | 0.999 | N | 0.665 | 0.591 | 0.491387584038 | gnomAD-4.0.0 | 1.59145E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| Q/H | 34966 |
Ig-163 |
25 | rs1689181377 |
0.8096 | None | 0.999 | D | 0.59 | 0.292 | 0.33835085245 | gnomAD-4.0.0 | 1.59088E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77239E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Q/P | 34966 |
Ig-163 |
25 | rs1225108277 |
0.9039 | 0.005 | 0.999 | N | 0.651 | 0.596 | 0.551677396071 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| Q/P | 34966 |
Ig-163 |
25 | rs1225108277 |
0.9039 | 0.005 | 0.999 | N | 0.651 | 0.596 | 0.551677396071 | gnomAD-4.0.0 | 2.05242E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6982E-06 | 0 | 0 |
| Q/R | 34966 |
Ig-163 |
25 | rs1225108277 |
0.561 | None | 0.997 | N | 0.489 | 0.433 | 0.255777322467 | gnomAD-4.0.0 | 1.36828E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99399E-07 | 1.15931E-05 | 0 |
| D/N | 35153 |
Ig-164 |
25 | rs778907927 |
0.5105 | -1.548 | 1.0 | N | 0.549 | 0.398 | 0.357929162469 | gnomAD-2.1.1 | 1.78E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.53594E-04 | None | 3.27E-05 | None | 0 | 7.79E-06 | 0 |
| D/N | 35153 |
Ig-164 |
25 | rs778907927 |
0.5105 | -1.548 | 1.0 | N | 0.549 | 0.398 | 0.357929162469 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92382E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 35153 |
Ig-164 |
25 | rs778907927 |
0.5105 | -1.548 | 1.0 | N | 0.549 | 0.398 | 0.357929162469 | gnomAD-4.0.0 | 6.81589E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.68181E-05 | None | 0 | 0 | 4.23767E-06 | 1.09791E-05 | 3.20174E-05 |
| S/G | 35310 |
Ig-165 |
25 | None | 0.0793 | None | 0.089 | N | 0.353 | 0.111 | 0.144782658237 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| S/N | 35310 |
Ig-165 |
25 | rs1553484229 |
0.105 | None | 0.001 | N | 0.118 | 0.036 | 0.0716867268079 | gnomAD-4.0.0 | 1.59091E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85757E-06 | 0 | 0 |
| S/T | 35310 |
Ig-165 |
25 | rs1553484229 |
0.0799 | None | 0.001 | N | 0.123 | 0.057 | 0.0762999501168 | gnomAD-4.0.0 | 1.59091E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85757E-06 | 0 | 0 |
| T/A | 35444 |
Ig-166 |
25 | rs1688516881 |
0.0928 | None | 0.002 | N | 0.149 | 0.134 | 0.209622950755 | gnomAD-4.0.0 | 1.36984E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0037E-07 | 0 | 1.65832E-05 |
| T/I | 35444 |
Ig-166 |
25 | rs1452745293 |
0.1682 | 0.142 | 0.863 | N | 0.522 | 0.329 | 0.464784125046 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| T/I | 35444 |
Ig-166 |
25 | rs1452745293 |
0.1682 | 0.142 | 0.863 | N | 0.522 | 0.329 | 0.464784125046 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 35444 |
Ig-166 |
25 | rs1452745293 |
0.1682 | 0.142 | 0.863 | N | 0.522 | 0.329 | 0.464784125046 | gnomAD-4.0.0 | 3.85081E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19891E-06 | 0 | 0 |
| T/P | 35444 |
Ig-166 |
25 | None | 0.2768 | None | 0.928 | N | 0.527 | 0.473 | 0.410204130746 | gnomAD-4.0.0 | 6.84922E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0037E-07 | 0 | 0 |
| A/T | 35631 |
Ig-167 |
25 | None | 0.102 | None | 0.549 | N | 0.184 | 0.086 | 0.240491677333 | gnomAD-4.0.0 | 1.36829E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87287E-05 | 0 | 8.99395E-07 | 0 | 0 |
| S/T | 35726 |
Ig-168 |
25 | None | 0.069 | None | None | N | 0.093 | 0.063 | 0.137902524267 | gnomAD-4.0.0 | 6.84712E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99964E-07 | 0 | 0 |
| T/K | 35921 |
Ig-169 |
25 | rs749277200 |
0.3035 | None | 0.608 | N | 0.327 | 0.347 | 0.458734620958 | gnomAD-4.0.0 | 6.84226E-07 | None | None | None | -0.446(OBSL1) 0.235(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99463E-07 | 0 | 0 |
| T/M | 35921 |
Ig-169 |
25 | rs749277200 |
0.1534 | 0.148 | 0.998 | D | 0.351 | 0.441 | 0.756686942875 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | 0.374(OBSL1) 0.673(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| T/M | 35921 |
Ig-169 |
25 | rs749277200 |
0.1534 | 0.148 | 0.998 | D | 0.351 | 0.441 | 0.756686942875 | gnomAD-4.0.0 | 6.84226E-06 | None | None | None | 0.374(OBSL1) 0.673(OBSCN) | N | None | 2.98739E-05 | 0 | None | 0 | 0 | None | 1.87308E-05 | 0 | 7.19571E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.