Structural position:

  • Domain Type: Ig
  • Aligned Position: 44
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
P/A 35 Ig-1 30 rs779420414 0.7278 -2.045 1.0 D 0.789 0.705 0.534907319155 gnomAD-2.1.1 1.6E-05 None None None -0.303(TCAP) N None 0 0 None 0 0 None 1.30745E-04 None 0 0 0
P/A 35 Ig-1 30 rs779420414 0.7278 -2.045 1.0 D 0.789 0.705 0.534907319155 gnomAD-4.0.0 6.36349E-06 None None None -0.303(TCAP) N None 0 0 None 0 0 None 0 0 0 5.73197E-05 0
P/L 35 Ig-1 30 rs755605142 0.89 -0.544 1.0 D 0.825 0.75 0.837958248163 gnomAD-2.1.1 7.97E-06 None None None -0.7(TCAP) N None 0 0 None 0 0 None 0 None 0 1.76E-05 0
P/L 35 Ig-1 30 rs755605142 0.89 -0.544 1.0 D 0.825 0.75 0.837958248163 gnomAD-4.0.0 3.18161E-06 None None None -0.7(TCAP) N None 0 0 None 0 0 None 0 0 5.7138E-06 0 0
P/T 35 Ig-1 30 rs779420414 0.919 -2.156 1.0 D 0.836 0.801 0.734031765732 gnomAD-2.1.1 3.99E-06 None None None -0.325(TCAP) N None 6.16E-05 0 None 0 0 None 0 None 0 0 0
P/T 35 Ig-1 30 rs779420414 0.919 -2.156 1.0 D 0.836 0.801 0.734031765732 gnomAD-3.1.2 6.57E-06 None None None -0.325(TCAP) N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/T 35 Ig-1 30 rs779420414 0.919 -2.156 1.0 D 0.836 0.801 0.734031765732 gnomAD-4.0.0 6.57082E-06 None None None -0.325(TCAP) N None 2.41278E-05 0 None 0 0 None 0 0 0 0 0
P/A 133 Ig-2 30 rs556390708 0.6894 None 0.252 D 0.443 0.649 None gnomAD-3.1.2 6.57E-06 None None None -0.583(TCAP) N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/A 133 Ig-2 30 rs556390708 0.6894 None 0.252 D 0.443 0.649 None gnomAD-4.0.0 6.57082E-06 None None None -0.583(TCAP) N None 2.41371E-05 0 None 0 0 None 0 0 0 0 0
P/L 133 Ig-2 30 None 0.9385 None 0.999 D 0.747 0.652 0.875033115104 gnomAD-4.0.0 1.59062E-06 None None None -0.94(TCAP) N None 0 0 None 0 0 None 0 0 2.85662E-06 0 0
P/S 133 Ig-2 30 rs556390708 0.953 -2.096 0.977 D 0.657 0.721 0.548443230319 gnomAD-3.1.2 6.57E-06 None None None -0.664(TCAP) N None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
P/S 133 Ig-2 30 rs556390708 0.953 -2.096 0.977 D 0.657 0.721 0.548443230319 1000 genomes 1.99681E-04 None None None -0.664(TCAP) N None 0 0 None None 0 0 None None None 1E-03 None
P/S 133 Ig-2 30 rs556390708 0.953 -2.096 0.977 D 0.657 0.721 0.548443230319 gnomAD-4.0.0 6.56573E-06 None None None -0.664(TCAP) N None 0 0 None 0 0 None 0 0 0 2.07297E-04 0
P/T 133 Ig-2 30 None 0.9363 None 0.543 D 0.447 0.722 0.582170006919 gnomAD-4.0.0 2.40064E-06 None None None -0.838(TCAP) N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/L 972 Ig-3 30 rs540920622 0.9446 -0.687 1.0 D 0.844 0.578 0.885469739524 gnomAD-2.1.1 7.98E-06 None None None None I None 6.19E-05 0 None 0 0 None 0 None 0 8.83E-06 0
P/L 972 Ig-3 30 rs540920622 0.9446 -0.687 1.0 D 0.844 0.578 0.885469739524 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/L 972 Ig-3 30 rs540920622 0.9446 -0.687 1.0 D 0.844 0.578 0.885469739524 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
P/L 972 Ig-3 30 rs540920622 0.9446 -0.687 1.0 D 0.844 0.578 0.885469739524 gnomAD-4.0.0 4.33687E-06 None None None None I None 1.33291E-05 0 None 0 0 None 0 0 4.23736E-06 1.09796E-05 0
P/Q 972 Ig-3 30 rs540920622 0.9926 None 1.0 D 0.852 0.569 0.751870096423 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/Q 972 Ig-3 30 rs540920622 0.9926 None 1.0 D 0.852 0.569 0.751870096423 gnomAD-4.0.0 6.57307E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46998E-05 0 0
P/L 1111 Ig-4 30 None 0.9457 None 1.0 D 0.819 0.759 0.86771504586 gnomAD-4.0.0 1.59051E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/S 1111 Ig-4 30 rs727504210 0.9812 -2.364 1.0 D 0.82 0.747 0.620428437143 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.82E-06 0
P/S 1111 Ig-4 30 rs727504210 0.9812 -2.364 1.0 D 0.82 0.747 0.620428437143 gnomAD-4.0.0 7.52477E-06 None None None None N None 0 0 None 0 0 None 0 0 9.8923E-06 0 0
P/S 1320 Ig-5 30 None 0.9797 None 1.0 D 0.818 0.784 0.62988413793 gnomAD-4.0.0 2.05301E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79894E-06 0 1.65607E-05
P/L 1486 Ig-6 30 None 0.9727 None 1.0 D 0.831 0.716 0.835052448565 gnomAD-4.0.0 1.59079E-06 None None None None I None 0 2.28676E-05 None 0 0 None 0 0 0 0 0
M/T 1734 Ig-8 32 rs1379908886 0.9446 -0.708 0.994 D 0.699 0.603 0.852533650957 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.83E-06 0
M/T 1734 Ig-8 32 rs1379908886 0.9446 -0.708 0.994 D 0.699 0.603 0.852533650957 gnomAD-4.0.0 7.52501E-06 None None None None I None 0 0 None 0 0 None 0 0 9.89219E-06 0 0
M/V 1734 Ig-8 32 None 0.4967 None 0.985 N 0.543 0.411 0.578877614382 gnomAD-4.0.0 1.36818E-06 None None None None I None 0 2.23664E-05 None 0 0 None 0 0 8.9929E-07 0 0
P/S 1870 Ig-9 30 None 0.9802 None 1.0 D 0.832 0.795 0.577304025972 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/R 2107 Ig-10 30 None 0.9959 None 1.0 D 0.843 0.828 0.692713709614 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
V/A 2203 Ig-11 30 rs746433556 0.3267 -2.196 0.334 N 0.507 0.391 0.432826170204 gnomAD-2.1.1 7.97E-06 None None None None N None 1.23062E-04 0 None 0 0 None 0 None 0 0 0
V/A 2203 Ig-11 30 rs746433556 0.3267 -2.196 0.334 N 0.507 0.391 0.432826170204 gnomAD-3.1.2 5.26E-05 None None None None N None 1.93115E-04 0 0 0 0 None 0 0 0 0 0
V/A 2203 Ig-11 30 rs746433556 0.3267 -2.196 0.334 N 0.507 0.391 0.432826170204 gnomAD-4.0.0 9.91375E-06 None None None None N None 2.13641E-04 0 None 0 0 None 0 0 0 0 0
V/F 2203 Ig-11 30 rs768181882 0.3425 -1.443 0.638 D 0.784 0.381 0.675055277813 gnomAD-2.1.1 3.99E-06 None None None None N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
V/F 2203 Ig-11 30 rs768181882 0.3425 -1.443 0.638 D 0.784 0.381 0.675055277813 gnomAD-4.0.0 2.73647E-06 None None None None N None 1.19524E-04 0 None 0 0 None 0 0 0 0 0
V/I 2203 Ig-11 30 rs768181882 0.0822 -0.704 0.001 N 0.233 0.094 0.256283259241 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 5.45E-05 None 0 None 0 0 0
V/I 2203 Ig-11 30 rs768181882 0.0822 -0.704 0.001 N 0.233 0.094 0.256283259241 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/I 2203 Ig-11 30 rs768181882 0.0822 -0.704 0.001 N 0.233 0.094 0.256283259241 gnomAD-4.0.0 6.57099E-06 None None None None N None 0 0 None 0 0 None 0 0 1.4699E-05 0 0
I/M 2295 Ig-12 29 None 0.0797 None 0.427 N 0.546 0.135 0.24896430686 gnomAD-4.0.0 1.36821E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79865E-06 0 0
I/V 2295 Ig-12 29 rs1239511094 0.0576 -1.102 None N 0.129 0.116 0.244539031024 gnomAD-2.1.1 3.98E-06 None None None None N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
I/V 2295 Ig-12 29 rs1239511094 0.0576 -1.102 None N 0.129 0.116 0.244539031024 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 2295 Ig-12 29 rs1239511094 0.0576 -1.102 None N 0.129 0.116 0.244539031024 gnomAD-4.0.0 3.84198E-06 None None None None N None 5.07185E-05 0 None 0 0 None 0 0 0 0 0
T/S 2474 Ig-14 30 rs750891001 0.1037 -0.038 None N 0.118 0.067 0.143124449307 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.83E-06 0
I/M 2561 Ig-15 29 None 0.1718 None 0.998 N 0.615 0.323 0.579008800273 gnomAD-4.0.0 1.59086E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8567E-06 0 0
I/T 2561 Ig-15 29 rs747031357 0.3817 -1.804 0.989 D 0.645 0.633 0.762922086239 gnomAD-2.1.1 2.13E-05 None None None None N None 0 0 None 0 0 None 1.3071E-04 None 0 7.76E-06 1.39005E-04
I/T 2561 Ig-15 29 rs747031357 0.3817 -1.804 0.989 D 0.645 0.633 0.762922086239 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 2.07039E-04 0
I/T 2561 Ig-15 29 rs747031357 0.3817 -1.804 0.989 D 0.645 0.633 0.762922086239 gnomAD-4.0.0 1.98277E-05 None None None None N None 0 0 None 0 0 None 0 0 1.18644E-05 1.53711E-04 6.40205E-05
V/F 2823 Ig-18 29 rs33917087 0.5056 -1.527 0.997 D 0.785 0.424 None gnomAD-2.1.1 1.45513E-02 None None None None N None 2.88462E-03 9.0324E-03 None 4.05484E-03 1.00311E-04 None 2.41704E-03 None 2.39612E-02 2.23383E-02 1.66389E-02
V/F 2823 Ig-18 29 rs33917087 0.5056 -1.527 0.997 D 0.785 0.424 None gnomAD-3.1.2 1.55706E-02 None None None None N None 3.66831E-03 1.59811E-02 1.12939E-01 6.05886E-03 0 None 2.33786E-02 9.49367E-03 2.28729E-02 2.07039E-03 1.52818E-02
V/F 2823 Ig-18 29 rs33917087 0.5056 -1.527 0.997 D 0.785 0.424 None 1000 genomes 7.58786E-03 None None None None N None 8E-04 2.31E-02 None None 0 1.79E-02 None None None 3.1E-03 None
V/F 2823 Ig-18 29 rs33917087 0.5056 -1.527 0.997 D 0.785 0.424 None gnomAD-4.0.0 1.85661E-02 None None None None N None 3.3583E-03 1.18647E-02 None 4.52672E-03 6.68598E-05 None 2.30531E-02 6.92841E-03 2.21007E-02 2.59101E-03 1.48931E-02
I/F 2997 Ig-20 29 rs879242806 0.5131 None 0.997 D 0.617 0.378 0.559465614996 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/F 2997 Ig-20 29 rs879242806 0.5131 None 0.997 D 0.617 0.378 0.559465614996 gnomAD-4.0.0 1.23915E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69489E-06 0 0
I/M 2997 Ig-20 29 None 0.311 None 0.997 N 0.599 0.306 0.568465717781 gnomAD-4.0.0 6.84095E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99297E-07 0 0
I/V 2997 Ig-20 29 None 0.121 None 0.889 N 0.407 0.218 0.634606890218 gnomAD-4.0.0 9.57734E-06 None None None None N None 0 0 None 0 2.52181E-05 None 0 0 1.16909E-05 0 0
I/L 3086 Ig-21 29 rs2090827474 0.3797 None 0.005 N 0.141 0.219 0.247872288689 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/L 3086 Ig-21 29 rs2090827474 0.3797 None 0.005 N 0.141 0.219 0.247872288689 gnomAD-4.0.0 6.56918E-06 None None None None N None 2.4122E-05 0 None 0 0 None 0 0 0 0 0
I/V 3086 Ig-21 29 rs2090827474 0.1261 None 0.005 N 0.123 0.146 0.316198179892 gnomAD-4.0.0 1.59055E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
V/I 3175 Ig-22 29 rs762667276 0.103 -0.555 0.014 N 0.244 0.152 0.241078983079 gnomAD-2.1.1 1.03672E-04 None None None None N None 0 0 None 0 0 None 8.49285E-04 None 0 0 0
V/I 3175 Ig-22 29 rs762667276 0.103 -0.555 0.014 N 0.244 0.152 0.241078983079 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07125E-04 0
V/I 3175 Ig-22 29 rs762667276 0.103 -0.555 0.014 N 0.244 0.152 0.241078983079 gnomAD-4.0.0 4.70889E-05 None None None None N None 0 0 None 0 0 None 0 0 0 8.34395E-04 0
V/L 3175 Ig-22 29 rs762667276 0.7495 None 0.247 N 0.436 0.334 0.241078983079 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 3175 Ig-22 29 rs762667276 0.7495 None 0.247 N 0.436 0.334 0.241078983079 gnomAD-4.0.0 1.23918E-06 None None None None N None 0 0 None 0 0 None 0 0 1.6949E-06 0 0
P/S 3268 Ig-23 30 rs912372716 0.9399 -1.939 1.0 D 0.834 0.703 None gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 1.63345E-04
P/S 3268 Ig-23 30 rs912372716 0.9399 -1.939 1.0 D 0.834 0.703 None gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 3268 Ig-23 30 rs912372716 0.9399 -1.939 1.0 D 0.834 0.703 None gnomAD-4.0.0 4.39906E-05 None None None None N None 1.33504E-05 0 None 0 0 None 0 6.58111E-04 5.50847E-05 0 1.60041E-05
L/P 3373 Ig-24 29 None 0.6785 None 1.0 N 0.744 0.627 0.798287381842 gnomAD-4.0.0 1.36831E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79872E-06 0 0
P/A 3494 Ig-25 30 rs1561101666 0.5234 None None None None 0.404 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
P/A 3494 Ig-25 30 rs1561101666 0.5234 None None None None 0.404 None gnomAD-4.0.0 1.5911E-06 None None None None N None 0 0 None 0 2.77346E-05 None 0 0 0 0 0
I/T 3689 Ig-26 30 rs527924868 0.0742 -2.361 None None None 0.141 None gnomAD-2.1.1 1.49997E-04 None None None None N None 4.13E-05 2.83E-05 None 0 0 None 1.17655E-03 None 0 3.12E-05 0
I/T 3689 Ig-26 30 rs527924868 0.0742 -2.361 None None None 0.141 None gnomAD-3.1.2 1.11725E-04 None None None None N None 7.24E-05 0 0 0 0 None 0 0 4.41E-05 2.27932E-03 0
I/T 3689 Ig-26 30 rs527924868 0.0742 -2.361 None None None 0.141 None 1000 genomes 7.98722E-04 None None None None N None 0 0 None None 0 0 None None None 4.1E-03 None
I/T 3689 Ig-26 30 rs527924868 0.0742 -2.361 None None None 0.141 None gnomAD-4.0.0 9.54271E-05 None None None None N None 3.99776E-05 1.66694E-05 None 0 0 None 0 4.9505E-04 2.2885E-05 1.27361E-03 6.40164E-05
I/V 3689 Ig-26 30 rs1299991139 0.0769 None None None None 0.087 None gnomAD-4.0.0 1.59132E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85804E-06 0 0
P/L 3849 Ig-27 30 rs727503662 0.7018 None 1.0 D 0.887 0.607 None gnomAD-4.0.0 2.05263E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69844E-06 0 0
P/A 3967 Ig-28 30 None 0.3789 None 0.117 D 0.481 0.56 None gnomAD-4.0.0 1.59105E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
K/E 4633 Ig-29 28 rs773833776 0.1003 -1.342 None D 0.188 0.212 None gnomAD-2.1.1 3.57E-05 None None None None N None 0 0 None 6.77376E-04 0 None 0 None 0 2.35E-05 0
K/E 4633 Ig-29 28 rs773833776 0.1003 -1.342 None D 0.188 0.212 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 8.64553E-04 0 None 0 0 0 0 0
K/E 4633 Ig-29 28 rs773833776 0.1003 -1.342 None D 0.188 0.212 None gnomAD-4.0.0 1.30135E-05 None None None None N None 0 0 None 4.39189E-04 0 None 0 0 4.23798E-06 0 4.804E-05
K/I 4633 Ig-29 28 rs555756236 0.3393 0.589 0.171 N 0.717 0.291 None gnomAD-2.1.1 6.84E-05 None None None None N None 0 0 None 0 9.50145E-04 None 0 None 0 0 0
K/I 4633 Ig-29 28 rs555756236 0.3393 0.589 0.171 N 0.717 0.291 None gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 9.6302E-04 None 0 0 0 0 0
K/I 4633 Ig-29 28 rs555756236 0.3393 0.589 0.171 N 0.717 0.291 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
K/I 4633 Ig-29 28 rs555756236 0.3393 0.589 0.171 N 0.717 0.291 None gnomAD-4.0.0 3.96576E-05 None None None None N None 0 0 None 0 1.42787E-03 None 0 0 0 0 0
V/I 4729 Ig-30 30 rs1279065978 0.1131 -0.627 0.898 N 0.556 0.239 0.486209434461 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 5.61E-05 None 0 None 0 0 0
V/I 4729 Ig-30 30 rs1279065978 0.1131 -0.627 0.898 N 0.556 0.239 0.486209434461 gnomAD-4.0.0 1.59192E-06 None None None None I None 0 0 None 0 2.78195E-05 None 0 0 0 0 0
I/T 4824 Ig-31 30 None 0.2048 None 0.959 D 0.569 0.4 0.75913351157 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/V 4824 Ig-31 30 rs772792515 0.1171 -1.411 0.509 D 0.361 0.31 0.627389779515 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.58E-05 None 0 None 0 0 0
I/V 4824 Ig-31 30 rs772792515 0.1171 -1.411 0.509 D 0.361 0.31 0.627389779515 gnomAD-4.0.0 1.5913E-06 None None None None I None 0 0 None 0 2.77423E-05 None 0 0 0 0 0
V/I 4917 Ig-32 30 None 0.1102 None 0.997 D 0.583 0.416 0.70802241665 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
I/L 5197 Ig-35 30 rs781467868 0.1539 -0.794 0.02 N 0.23 0.116 0.3571064206 gnomAD-2.1.1 2.41E-05 None None None None N None 0 1.73853E-04 None 0 0 None 0 None 0 0 0
I/L 5197 Ig-35 30 rs781467868 0.1539 -0.794 0.02 N 0.23 0.116 0.3571064206 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.96541E-04 0 0 0 None 0 0 0 0 0
I/L 5197 Ig-35 30 rs781467868 0.1539 -0.794 0.02 N 0.23 0.116 0.3571064206 gnomAD-4.0.0 1.15295E-05 None None None None N None 0 1.52542E-04 None 0 0 None 0 0 0 0 0
M/I 5386 Ig-37 30 None 0.4854 None 0.005 N 0.137 0.306 0.295623431141 gnomAD-4.0.0 1.44039E-05 None None None None I None 0 0 None 0 0 None 0 0 1.44375E-05 0 3.66327E-05
M/L 5386 Ig-37 30 None 0.1422 None 0.136 N 0.317 0.297 0.419461527279 gnomAD-4.0.0 1.36867E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79906E-06 0 0
M/T 5386 Ig-37 30 rs375417155 0.7155 -1.75 0.801 N 0.589 0.426 None gnomAD-2.1.1 2.42E-05 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 4.45E-05 0
M/T 5386 Ig-37 30 rs375417155 0.7155 -1.75 0.801 N 0.589 0.426 None gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 4.78469E-04
M/T 5386 Ig-37 30 rs375417155 0.7155 -1.75 0.801 N 0.589 0.426 None gnomAD-4.0.0 2.16929E-05 None None None None I None 1.33494E-05 0 None 0 0 None 0 1.64528E-04 2.62775E-05 1.09801E-05 1.60159E-05
M/V 5386 Ig-37 30 rs567457007 0.1235 -1.59 0.267 N 0.361 0.329 None gnomAD-2.1.1 2.86E-05 None None None None I None 3.30989E-04 0 None 0 0 None 0 None 0 0 0
M/V 5386 Ig-37 30 rs567457007 0.1235 -1.59 0.267 N 0.361 0.329 None gnomAD-3.1.2 6.58E-05 None None None None I None 2.41383E-04 0 0 0 0 None 0 0 0 0 0
M/V 5386 Ig-37 30 rs567457007 0.1235 -1.59 0.267 N 0.361 0.329 None gnomAD-4.0.0 2.10724E-05 None None None None I None 3.73264E-04 0 None 0 0 None 0 0 0 0 9.60615E-05
I/S 5573 Ig-39 31 None 0.8424 None 0.998 N 0.685 0.5 0.895925552087 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
F/L 5666 Ig-40 30 None 0.8893 None 0.008 N 0.21 0.339 0.190952846119 gnomAD-4.0.0 3.18275E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85851E-06 1.43279E-05 0
I/V 5759 Ig-41 30 rs1365586736 0.088 -1.275 0.267 N 0.395 0.093 0.388174495139 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/V 5759 Ig-41 30 rs1365586736 0.088 -1.275 0.267 N 0.395 0.093 0.388174495139 gnomAD-4.0.0 2.73715E-06 None None None None I None 0 0 None 0 0 None 0 1.73551E-04 1.79901E-06 1.15939E-05 0
I/S 5852 Ig-42 30 None 0.8059 None 0.998 N 0.616 0.449 0.886848395655 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
I/V 5852 Ig-42 30 None 0.1526 None 0.689 N 0.327 0.149 0.531629458225 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 5948 Ig-43 30 rs772946744 0.9425 -2.37 0.822 N 0.619 0.34 0.743893448314 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.69E-05 0
I/T 5948 Ig-43 30 rs772946744 0.9425 -2.37 0.822 N 0.619 0.34 0.743893448314 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/T 5948 Ig-43 30 rs772946744 0.9425 -2.37 0.822 N 0.619 0.34 0.743893448314 gnomAD-4.0.0 1.2395E-05 None None None None N None 0 0 None 0 0 None 0 0 1.69535E-05 0 0
I/V 5948 Ig-43 30 rs780320662 0.1335 -1.704 0.294 N 0.421 0.191 0.550759897685 gnomAD-2.1.1 7.17E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.58E-05 0
I/V 5948 Ig-43 30 rs780320662 0.1335 -1.704 0.294 N 0.421 0.191 0.550759897685 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 5948 Ig-43 30 rs780320662 0.1335 -1.704 0.294 N 0.421 0.191 0.550759897685 gnomAD-4.0.0 6.81727E-06 None None None None N None 1.33486E-05 0 None 0 0 None 0 0 8.47675E-06 0 0
M/K 6041 Ig-44 30 None 0.54 None 0.028 N 0.421 0.42 0.555712064712 gnomAD-4.0.0 3.18735E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86141E-06 1.43583E-05 0
M/V 6041 Ig-44 30 rs756902355 0.0799 -1.349 None N 0.091 0.208 0.180583059064 gnomAD-2.1.1 7.2E-06 None None None None I None 8.3E-05 0 None 0 0 None 0 None 0 0 0
M/V 6041 Ig-44 30 rs756902355 0.0799 -1.349 None N 0.091 0.208 0.180583059064 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
M/V 6041 Ig-44 30 rs756902355 0.0799 -1.349 None N 0.091 0.208 0.180583059064 gnomAD-4.0.0 2.5655E-06 None None None None I None 3.38249E-05 0 None 0 0 None 0 0 0 0 0
I/V 6135 Ig-45 31 rs935669018 0.1749 None 0.993 D 0.38 0.287 0.580574400314 gnomAD-3.1.2 1.31E-05 None None None None N None 0 1.31182E-04 0 0 0 None 0 0 0 0 0
I/V 6135 Ig-45 31 rs935669018 0.1749 None 0.993 D 0.38 0.287 0.580574400314 gnomAD-4.0.0 3.84409E-06 None None None None N None 1.69159E-05 3.39271E-05 None 0 0 None 0 0 0 0 0
F/S 6228 Ig-46 30 rs1192303175 0.652 -2.888 0.991 N 0.705 0.495 0.784914850903 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
F/S 6228 Ig-46 30 rs1192303175 0.652 -2.888 0.991 N 0.705 0.495 0.784914850903 gnomAD-4.0.0 1.59172E-06 None None None None N None 0 2.28739E-05 None 0 0 None 0 0 0 0 0
I/V 6321 Ig-47 30 rs145204073 0.0886 -1.487 0.041 N 0.39 0.125 None gnomAD-2.1.1 4.95336E-04 None None None None I None 5.38218E-03 1.7136E-04 None 0 0 None 0 None 0 7.95E-06 1.42248E-04
I/V 6321 Ig-47 30 rs145204073 0.0886 -1.487 0.041 N 0.39 0.125 None gnomAD-3.1.2 1.42064E-03 None None None None I None 5.04514E-03 3.27869E-04 0 0 0 None 0 0 1.47E-05 2.07469E-04 0
I/V 6321 Ig-47 30 rs145204073 0.0886 -1.487 0.041 N 0.39 0.125 None 1000 genomes 3.19489E-03 None None None None I None 1.21E-02 0 None None 0 0 None None None 0 None
I/V 6321 Ig-47 30 rs145204073 0.0886 -1.487 0.041 N 0.39 0.125 None gnomAD-4.0.0 2.59231E-04 None None None None I None 5.01454E-03 2.34114E-04 None 0 0 None 0 0 9.32798E-06 2.20022E-05 2.403E-04
I/T 6510 Ig-49 30 rs775784361 0.7473 -1.956 0.939 N 0.643 0.413 0.683080398064 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 4.66E-05 0 0
I/T 6510 Ig-49 30 rs775784361 0.7473 -1.956 0.939 N 0.643 0.413 0.683080398064 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 0 4.78011E-04
I/T 6510 Ig-49 30 rs775784361 0.7473 -1.956 0.939 N 0.643 0.413 0.683080398064 gnomAD-4.0.0 2.5641E-06 None None None None I None 0 0 None 0 0 None 1.57164E-05 0 0 0 2.8477E-05
I/V 6510 Ig-49 30 rs761041978 0.0914 -1.501 0.02 N 0.198 0.138 None gnomAD-2.1.1 1.43E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.14E-05 0
I/V 6510 Ig-49 30 rs761041978 0.0914 -1.501 0.02 N 0.198 0.138 None gnomAD-3.1.2 2.63E-05 None None None None I None 0 0 0 0 0 None 0 0 5.88E-05 0 0
I/V 6510 Ig-49 30 rs761041978 0.0914 -1.501 0.02 N 0.198 0.138 None gnomAD-4.0.0 3.84345E-05 None None None None I None 0 0 None 0 0 None 1.56455E-05 0 5.00198E-05 0 3.2042E-05
F/L 6790 Ig-52 30 None 0.975 None 0.999 N 0.555 0.264 0.284539287134 gnomAD-4.0.0 4.78245E-06 None None None None I None 0 6.87758E-05 None 0 0 None 0 0 0 0 0
I/M 6883 Ig-53 30 rs2079192299 0.2249 None 0.31 N 0.207 0.11 0.416075642716 gnomAD-4.0.0 1.59266E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86053E-06 0 0
I/S 6883 Ig-53 30 rs1392708886 0.7545 -2.925 0.959 N 0.529 0.445 0.88295878216 gnomAD-4.0.0 1.36891E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79937E-06 0 0
I/T 6883 Ig-53 30 None 0.7285 None 0.959 N 0.485 0.323 0.739771329103 gnomAD-4.0.0 6.84454E-07 None None None None N None 0 0 None 0 0 None 1.87336E-05 0 0 0 0
I/V 6883 Ig-53 30 None 0.0889 None 0.509 N 0.34 0.17 0.618380283371 gnomAD-4.0.0 1.59273E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02645E-05
L/H 6977 Ig-54 30 None 0.9135 None 1.0 D 0.683 0.639 0.887685046922 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
L/P 6977 Ig-54 30 rs1201922048 0.69 -1.684 1.0 N 0.765 0.538 0.768461157586 gnomAD-2.1.1 3.19E-05 None None None None I None 1.14916E-04 0 None 0 0 None 0 None 0 0 0
L/P 6977 Ig-54 30 rs1201922048 0.69 -1.684 1.0 N 0.765 0.538 0.768461157586 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
L/P 6977 Ig-54 30 rs1201922048 0.69 -1.684 1.0 N 0.765 0.538 0.768461157586 gnomAD-4.0.0 6.57583E-06 None None None None I None 2.41359E-05 0 None 0 0 None 0 0 0 0 0
I/M 7073 Ig-55 30 None 0.2398 None 0.136 N 0.233 0.068 0.296679040009 gnomAD-4.0.0 1.59199E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8595E-06 0 0
I/V 7073 Ig-55 30 rs1321725183 0.1163 -1.549 0.267 N 0.383 0.139 0.415055319159 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
F/C 7166 Ig-56 30 rs781740874 0.4455 -1.555 0.997 N 0.593 0.517 0.809359663723 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.57E-05 0
F/C 7166 Ig-56 30 rs781740874 0.4455 -1.555 0.997 N 0.593 0.517 0.809359663723 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
F/C 7166 Ig-56 30 rs781740874 0.4455 -1.555 0.997 N 0.593 0.517 0.809359663723 gnomAD-4.0.0 5.57935E-06 None None None None N None 0 0 None 0 0 None 0 0 6.78229E-06 0 1.60231E-05
I/M 7259 Ig-57 30 rs727505220 0.3181 -0.964 1.0 N 0.747 0.346 0.602320007227 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 0 0
I/M 7259 Ig-57 30 rs727505220 0.3181 -0.964 1.0 N 0.747 0.346 0.602320007227 gnomAD-4.0.0 6.84303E-07 None None None None I None 0 0 None 0 2.52029E-05 None 0 0 0 0 0
I/T 7448 Ig-59 30 rs878854293 0.7661 None 0.98 N 0.635 0.375 0.756846489486 gnomAD-4.0.0 4.80129E-06 None None None None I None 0 0 None 0 0 None 0 0 5.25001E-06 0 0
I/V 7448 Ig-59 30 rs1349950887 0.1131 None 0.689 N 0.425 0.143 0.52851136469 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 7448 Ig-59 30 rs1349950887 0.1131 None 0.689 N 0.425 0.143 0.52851136469 gnomAD-4.0.0 2.56325E-06 None None None None I None 0 0 None 0 0 None 0 0 4.78863E-06 0 0
M/K 7544 Ig-60 30 None 0.6217 None 0.006 D 0.205 0.356 0.655352004 gnomAD-4.0.0 1.36872E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79927E-06 0 0
M/L 7544 Ig-60 30 rs2078457617 0.1115 None None N 0.075 0.227 0.546824882953 gnomAD-3.1.2 2.63E-05 None None None None I None 0 2.61917E-04 0 0 0 None 0 0 0 0 0
M/L 7544 Ig-60 30 rs2078457617 0.1115 None None N 0.075 0.227 0.546824882953 gnomAD-4.0.0 3.71886E-06 None None None None I None 0 6.66778E-05 None 0 0 None 1.56216E-05 0 8.47756E-07 0 0
M/T 7544 Ig-60 30 rs1234192175 0.4766 None 0.302 N 0.428 0.32 0.801681314988 gnomAD-4.0.0 6.8436E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99635E-07 0 0
I/N 7638 Ig-61 31 rs1266131698 0.8459 -2.194 0.994 N 0.743 0.449 0.885801658293 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
I/N 7638 Ig-61 31 rs1266131698 0.8459 -2.194 0.994 N 0.743 0.449 0.885801658293 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
I/N 7638 Ig-61 31 rs1266131698 0.8459 -2.194 0.994 N 0.743 0.449 0.885801658293 gnomAD-4.0.0 2.56364E-06 None None None None N None 0 3.3896E-05 None 0 0 None 0 0 0 0 0
I/V 7638 Ig-61 31 rs1489491529 0.2056 -1.623 0.589 N 0.447 0.174 0.488477830397 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
I/V 7638 Ig-61 31 rs1489491529 0.2056 -1.623 0.589 N 0.447 0.174 0.488477830397 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
L/F 7918 Ig-64 30 rs767543848 0.6247 -1.462 0.032 N 0.353 0.453 0.444706120422 gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 2.56226E-04 None 0 None 0 0 0
L/F 7918 Ig-64 30 rs767543848 0.6247 -1.462 0.032 N 0.353 0.453 0.444706120422 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 3.87297E-04 None 0 0 0 0 0
L/F 7918 Ig-64 30 rs767543848 0.6247 -1.462 0.032 N 0.353 0.453 0.444706120422 gnomAD-4.0.0 3.84394E-06 None None None None I None 0 0 None 0 7.27696E-05 None 0 0 0 0 0
I/T 8014 Ig-65 30 rs1415104830 0.8568 None 0.896 D 0.687 0.374 0.733027900626 gnomAD-3.1.2 1.32E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
I/T 8014 Ig-65 30 rs1415104830 0.8568 None 0.896 D 0.687 0.374 0.733027900626 gnomAD-4.0.0 2.47888E-06 None None None None I None 4.0062E-05 0 None 0 0 None 0 0 8.47636E-07 0 0
I/M 8200 Ig-67 30 rs2077838172 0.3404 None 0.267 N 0.447 0.124 0.354183961838 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/M 8200 Ig-67 30 rs2077838172 0.3404 None 0.267 N 0.447 0.124 0.354183961838 gnomAD-4.0.0 3.04487E-06 None None None None N None 0 0 None 0 0 None 0 0 3.61479E-06 0 0
I/T 8200 Ig-67 30 rs2077838539 0.8385 None 0.801 N 0.658 0.326 0.658673760821 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/T 8200 Ig-67 30 rs2077838539 0.8385 None 0.801 N 0.658 0.326 0.658673760821 gnomAD-4.0.0 6.57168E-06 None None None None N None 2.41278E-05 0 None 0 0 None 0 0 0 0 0
I/V 8200 Ig-67 30 rs1439095726 0.0808 -1.607 0.051 N 0.167 0.081 0.420939154896 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/V 8200 Ig-67 30 rs1439095726 0.0808 -1.607 0.051 N 0.167 0.081 0.420939154896 gnomAD-4.0.0 1.59144E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
I/L 8485 Ig-70 30 None 0.134 None None N 0.097 0.229 0.344945010812 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/V 8485 Ig-70 30 rs1560628327 0.0996 None 0.006 N 0.312 0.163 0.47282010386 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 8485 Ig-70 30 rs1560628327 0.0996 None 0.006 N 0.312 0.163 0.47282010386 gnomAD-4.0.0 1.3194E-05 None None None None I None 0 0 None 0 0 None 0 0 1.5664E-05 0 0
I/F 8579 Ig-71 31 None 0.3921 None 0.013 D 0.349 0.307 0.513280433867 gnomAD-4.0.0 6.84841E-07 None None None None I None 2.98989E-05 0 None 0 0 None 0 0 0 0 0
I/V 8579 Ig-71 31 None 0.1879 None 0.035 D 0.387 0.158 0.556183318313 gnomAD-4.0.0 1.36968E-06 None None None None I None 0 0 None 0 0 None 0 0 8.99977E-07 1.1629E-05 0
I/T 8765 Ig-73 30 rs768619883 0.5816 -2.622 0.976 N 0.615 0.42 0.776600623924 gnomAD-2.1.1 2.02E-05 None None None None N None 6.46E-05 8.71E-05 None 0 5.57E-05 None 0 None 0 0 0
I/T 8765 Ig-73 30 rs768619883 0.5816 -2.622 0.976 N 0.615 0.42 0.776600623924 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/T 8765 Ig-73 30 rs768619883 0.5816 -2.622 0.976 N 0.615 0.42 0.776600623924 gnomAD-4.0.0 1.28144E-05 None None None None N None 3.38409E-05 5.08613E-05 None 0 2.42518E-05 None 0 0 7.18061E-06 0 2.84527E-05
I/V 8765 Ig-73 30 rs776531934 0.0801 -1.518 0.192 D 0.441 0.124 0.581442141994 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
I/V 8765 Ig-73 30 rs776531934 0.0801 -1.518 0.192 D 0.441 0.124 0.581442141994 gnomAD-4.0.0 1.59174E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85901E-06 0 0
L/I 8859 Ig-74 30 rs1361604566 0.1428 -1.245 0.884 N 0.401 0.214 0.447311733946 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.58E-05 None 0 None 0 0 0
L/I 8859 Ig-74 30 rs1361604566 0.1428 -1.245 0.884 N 0.401 0.214 0.447311733946 gnomAD-4.0.0 1.59159E-06 None None None None I None 0 0 None 0 2.77331E-05 None 0 0 0 0 0
I/V 8955 Ig-75 30 rs72648994 0.1015 -1.498 0.677 N 0.359 0.094 None gnomAD-2.1.1 3.78195E-03 None None None None N None 8.39E-05 1.44159E-04 None 0 0 None 7.2337E-03 None 2.60887E-02 1.1886E-03 3E-03
I/V 8955 Ig-75 30 rs72648994 0.1015 -1.498 0.677 N 0.359 0.094 None gnomAD-3.1.2 2.72132E-03 None None None None N None 9.65E-05 1.96515E-04 0 0 0 None 2.69608E-02 0 1.35278E-03 5.80431E-03 4.78011E-04
I/V 8955 Ig-75 30 rs72648994 0.1015 -1.498 0.677 N 0.359 0.094 None 1000 genomes 2.19649E-03 None None None None N None 0 0 None None 0 4E-03 None None None 7.2E-03 None
I/V 8955 Ig-75 30 rs72648994 0.1015 -1.498 0.677 N 0.359 0.094 None gnomAD-4.0.0 2.25398E-03 None None None None N None 1.46631E-04 1.34197E-04 None 0 0 None 2.67376E-02 2.47688E-03 9.86148E-04 7.09973E-03 1.3624E-03
F/L 9048 Ig-76 30 None 0.6866 None 0.002 N 0.099 0.189 0.317084106153 gnomAD-4.0.0 1.59175E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43365E-05 0
F/V 9048 Ig-76 30 None 0.306 None 0.454 N 0.373 0.205 0.433823933641 gnomAD-4.0.0 1.59175E-06 None None None None N None 5.65611E-05 0 None 0 0 None 0 0 0 0 0
I/V 9141 Ig-77 30 None 0.0821 None None N 0.163 0.057 0.170165803431 gnomAD-4.0.0 1.59126E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85817E-06 0 0
I/M 9330 Ig-79 30 rs370277987 0.1635 -1.447 0.012 None 0.427 0.084 None gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
I/M 9330 Ig-79 30 rs370277987 0.1635 -1.447 0.012 None 0.427 0.084 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/M 9330 Ig-79 30 rs370277987 0.1635 -1.447 0.012 None 0.427 0.084 None gnomAD-4.0.0 1.79707E-05 None None None None N None 0 0 None 0 0 None 0 0 2.45805E-05 0 0
I/V 9330 Ig-79 30 rs768696299 0.095 -1.687 None None 0.151 0.087 None gnomAD-2.1.1 1.07E-05 None None None None N None 1.23998E-04 0 None 0 0 None 0 None 0 0 0
I/V 9330 Ig-79 30 rs768696299 0.095 -1.687 None None 0.151 0.087 None gnomAD-3.1.2 3.29E-05 None None None None N None 9.66E-05 6.55E-05 0 0 0 None 0 0 0 0 0
I/V 9330 Ig-79 30 rs768696299 0.095 -1.687 None None 0.151 0.087 None gnomAD-4.0.0 5.57706E-06 None None None None N None 1.06806E-04 1.66694E-05 None 0 0 None 0 0 0 0 0
I/T 9426 Ig-80 30 None 0.7722 None 0.994 None 0.619 0.362 0.734446920103 gnomAD-4.0.0 3.4208E-06 None None None None I None 0 0 None 0 0 None 0 0 3.59769E-06 0 1.65634E-05
I/L 9523 Ig-81 31 rs775239068 0.1121 -1.144 None None 0.113 0.143 0.307966526162 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
I/T 9523 Ig-81 31 rs2076388321 0.7851 None 0.175 None 0.574 0.278 0.670275282232 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 9523 Ig-81 31 rs2076388321 0.7851 None 0.175 None 0.574 0.278 0.670275282232 gnomAD-4.0.0 6.40462E-06 None None None None N None 0 0 None 0 0 None 0 0 1.19635E-05 0 0
I/V 9523 Ig-81 31 rs775239068 0.0839 None None None 0.147 0.074 0.504604281553 gnomAD-4.0.0 1.59108E-06 None None None None N None 0 0 None 4.76644E-05 0 None 0 0 0 0 0
I/F 9619 Ig-82 30 rs1446542554 0.5912 None 0.549 None 0.538 0.313 0.432604763906 gnomAD-4.0.0 6.84168E-07 None None None None I None 0 2.23634E-05 None 0 0 None 0 0 0 0 0
I/T 9619 Ig-82 30 rs530257812 0.81 -1.979 0.549 None 0.493 0.34 0.687710541463 gnomAD-2.1.1 4.01E-06 None None None None I None 0 0 None 0 5.56E-05 None 0 None 0 0 0
I/T 9619 Ig-82 30 rs530257812 0.81 -1.979 0.549 None 0.493 0.34 0.687710541463 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 1.92604E-04 None 0 0 0 0 0
I/T 9619 Ig-82 30 rs530257812 0.81 -1.979 0.549 None 0.493 0.34 0.687710541463 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 1E-03 0 None None None 0 None
I/T 9619 Ig-82 30 rs530257812 0.81 -1.979 0.549 None 0.493 0.34 0.687710541463 gnomAD-4.0.0 6.56564E-06 None None None None I None 0 0 None 0 1.9305E-04 None 0 0 0 0 0
I/V 9619 Ig-82 30 None 0.0991 None 0.099 None 0.344 0.116 0.44711355012 gnomAD-4.0.0 3.42084E-06 None None None None I None 0 0 None 0 0 None 0 0 3.5977E-06 0 1.65645E-05
P/L 9727 Ig-83 30 None 0.989 None 1.0 None 0.821 0.541 0.851167519305 gnomAD-4.0.0 1.369E-06 None None None None I None 2.98989E-05 0 None 0 0 None 0 0 8.9986E-07 0 0
P/S 9727 Ig-83 30 None 0.9927 None 1.0 None 0.824 0.564 0.614155820699 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/S 9930 Ig-84 31 rs757077819 0.9916 -1.884 1.0 None 0.773 0.556 0.894761999871 gnomAD-2.1.1 2.86E-05 None None None None I None 0 2.94E-05 None 0 0 None 0 None 0 5.43E-05 0
I/S 9930 Ig-84 31 rs757077819 0.9916 -1.884 1.0 None 0.773 0.556 0.894761999871 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/S 9930 Ig-84 31 rs757077819 0.9916 -1.884 1.0 None 0.773 0.556 0.894761999871 gnomAD-4.0.0 1.30308E-05 None None None None I None 0 1.67302E-05 None 0 0 None 0 0 1.69654E-05 0 0
I/T 9930 Ig-84 31 None 0.9889 None 1.0 None 0.748 0.5 0.767813838711 gnomAD-4.0.0 2.05567E-06 None None None None I None 0 0 None 0 0 None 0 0 2.70067E-06 0 0
I/V 9930 Ig-84 31 rs373215746 0.6112 -1.26 0.993 None 0.36 0.311 None gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 9930 Ig-84 31 rs373215746 0.6112 -1.26 0.993 None 0.36 0.311 None gnomAD-4.0.0 2.56861E-06 None None None None I None 3.38215E-05 0 None 0 0 None 0 0 0 0 0
V/L 10017 Ig-85 29 None 0.6179 None 0.026 None 0.253 0.197 0.415820034956 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
A/S 10106 Ig-86 29 None 0.5453 None 1.0 None 0.663 0.37 0.449379577644 gnomAD-4.0.0 1.59086E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
R/C 13808 Ig-88 29 rs375947044 0.4432 -0.216 1.0 N 0.817 0.197 None gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 6.55E-05 None 0 1.78E-05 0
R/C 13808 Ig-88 29 rs375947044 0.4432 -0.216 1.0 N 0.817 0.197 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 4.15628E-04 0
R/C 13808 Ig-88 29 rs375947044 0.4432 -0.216 1.0 N 0.817 0.197 None 1000 genomes 3.99361E-04 None None None None N None 0 0 None None 0 0 None None None 2E-03 None
R/C 13808 Ig-88 29 rs375947044 0.4432 -0.216 1.0 N 0.817 0.197 None gnomAD-4.0.0 9.29985E-06 None None None None N None 0 0 None 0 0 None 0 0 8.47872E-06 5.49318E-05 0
R/H 13808 Ig-88 29 rs764850788 0.333 -0.655 1.0 N 0.645 0.319 0.253726318573 gnomAD-2.1.1 2.02E-05 None None None None N None 0 0 None 0 1.69338E-04 None 0 None 0 1.78E-05 0
R/H 13808 Ig-88 29 rs764850788 0.333 -0.655 1.0 N 0.645 0.319 0.253726318573 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/H 13808 Ig-88 29 rs764850788 0.333 -0.655 1.0 N 0.645 0.319 0.253726318573 gnomAD-4.0.0 5.57979E-06 None None None None N None 0 0 None 0 4.48069E-05 None 0 0 5.93487E-06 0 0
R/S 13808 Ig-88 29 rs375947044 0.839 -0.22 0.996 N 0.586 0.175 0.221734844693 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
R/S 13808 Ig-88 29 rs375947044 0.839 -0.22 0.996 N 0.586 0.175 0.221734844693 gnomAD-4.0.0 6.84539E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.1599E-05 0
P/T 13902 Ig-89 27 rs865776326 0.574 None 1.0 N 0.796 0.432 0.400899426204 gnomAD-4.0.0 1.64128E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.49102E-05 0
I/V 13993 Ig-90 29 rs978359923 0.09 None None N 0.154 0.086 0.117506650769 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
A/T 14081 Ig-91 28 rs1174918107 0.2081 None 1.0 N 0.775 0.457 0.444605663662 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
A/T 14081 Ig-91 28 rs1174918107 0.2081 None 1.0 N 0.775 0.457 0.444605663662 gnomAD-4.0.0 2.56387E-06 None None None None N None 1.69337E-05 0 None 0 0 None 0 0 2.39446E-06 0 0
M/I 14170 Ig-92 29 rs1380128621 0.5513 -1.73 0.01 N 0.106 0.226 0.477143196806 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
M/I 14170 Ig-92 29 rs1380128621 0.5513 -1.73 0.01 N 0.106 0.226 0.477143196806 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
M/I 14170 Ig-92 29 rs1380128621 0.5513 -1.73 0.01 N 0.106 0.226 0.477143196806 gnomAD-4.0.0 6.84371E-07 None None None None N None 0 2.23654E-05 None 0 0 None 0 0 0 0 0
M/R 14170 Ig-92 29 rs369623392 0.4991 None 0.991 N 0.55 0.534 0.719157461425 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
M/R 14170 Ig-92 29 rs369623392 0.4991 None 0.991 N 0.55 0.534 0.719157461425 gnomAD-4.0.0 6.58233E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07039E-04 0
M/T 14170 Ig-92 29 rs369623392 0.4546 -1.227 0.679 N 0.422 0.359 None gnomAD-2.1.1 1.28754E-04 None None None None N None 0 0 None 0 0 None 0 None 1.99872E-04 2.35195E-04 1.40687E-04
M/T 14170 Ig-92 29 rs369623392 0.4546 -1.227 0.679 N 0.422 0.359 None gnomAD-3.1.2 7.24E-05 None None None None N None 4.83E-05 6.56E-05 0 0 0 None 0 0 1.17723E-04 0 0
M/T 14170 Ig-92 29 rs369623392 0.4546 -1.227 0.679 N 0.422 0.359 None gnomAD-4.0.0 1.53118E-04 None None None None N None 4.0093E-05 3.336E-05 None 0 0 None 1.56304E-04 0 1.91606E-04 0 9.61169E-05
M/V 14170 Ig-92 29 None 0.2038 None 0.01 N 0.105 0.203 0.44711355012 gnomAD-4.0.0 1.59213E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86013E-06 0 0
V/A 14347 Ig-94 29 rs747933690 0.6904 -1.561 0.997 N 0.556 0.306 0.425615883737 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
V/A 14347 Ig-94 29 rs747933690 0.6904 -1.561 0.997 N 0.556 0.306 0.425615883737 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/A 14347 Ig-94 29 rs747933690 0.6904 -1.561 0.997 N 0.556 0.306 0.425615883737 gnomAD-4.0.0 2.47967E-06 None None None None N None 0 0 None 0 0 None 0 0 3.39132E-06 0 0
V/I 14347 Ig-94 29 rs1009268757 0.1028 -0.575 0.994 N 0.599 0.293 0.428516003163 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
V/I 14347 Ig-94 29 rs1009268757 0.1028 -0.575 0.994 N 0.599 0.293 0.428516003163 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 14347 Ig-94 29 rs1009268757 0.1028 -0.575 0.994 N 0.599 0.293 0.428516003163 gnomAD-4.0.0 2.03006E-06 None None None None N None 1.74782E-05 0 None 0 0 None 0 0 1.20497E-06 0 0
K/E 14436 Ig-95 29 rs2059951786 0.1514 None 0.994 D 0.586 0.554 0.514072065251 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 9.41E-05 0 0 0 0
K/E 14436 Ig-95 29 rs2059951786 0.1514 None 0.994 D 0.586 0.554 0.514072065251 gnomAD-4.0.0 6.57566E-06 None None None None N None 0 0 None 0 0 None 9.40557E-05 0 0 0 0
K/N 14436 Ig-95 29 rs756686533 0.4003 -0.892 0.998 D 0.672 0.549 0.43046518545 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.97E-06 0
I/V 14525 Ig-96 29 rs2059904805 0.1625 None 0.198 N 0.217 0.091 0.306377322295 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
I/V 14525 Ig-96 29 rs2059904805 0.1625 None 0.198 N 0.217 0.091 0.306377322295 gnomAD-4.0.0 6.57549E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07039E-04 0
I/S 14703 Ig-98 29 rs2059714410 0.5321 None 0.664 N 0.445 0.325 0.490701487448 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/S 14703 Ig-98 29 rs2059714410 0.5321 None 0.664 N 0.445 0.325 0.490701487448 gnomAD-4.0.0 6.57575E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47024E-05 0 0
I/F 14792 Ig-99 28 rs536313527 0.4245 None 0.998 D 0.607 0.448 0.733197302235 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.94024E-04 None 0 0 0 0 0
I/F 14792 Ig-99 28 rs536313527 0.4245 None 0.998 D 0.607 0.448 0.733197302235 gnomAD-4.0.0 1.31377E-05 None None None None N None 0 0 None 0 3.88954E-04 None 0 0 0 0 0
I/M 14792 Ig-99 28 None 0.2881 None 0.998 N 0.579 0.226 0.596816321548 gnomAD-4.0.0 6.84613E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99836E-07 0 0
I/N 14792 Ig-99 28 rs747654057 0.6879 -2.055 0.999 D 0.722 0.534 0.887531180484 gnomAD-2.1.1 2.82E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.22E-05 0
I/N 14792 Ig-99 28 rs747654057 0.6879 -2.055 0.999 D 0.722 0.534 0.887531180484 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/N 14792 Ig-99 28 rs747654057 0.6879 -2.055 0.999 D 0.722 0.534 0.887531180484 gnomAD-4.0.0 3.53426E-05 None None None None N None 0 3.33578E-05 None 0 0 None 0 0 4.40942E-05 0 4.80692E-05
I/T 14792 Ig-99 28 rs747654057 0.6779 -2.448 0.989 N 0.605 0.471 None gnomAD-2.1.1 1.61E-05 None None None None N None 1.93899E-04 0 None 0 0 None 0 None 0 8.89E-06 0
I/T 14792 Ig-99 28 rs747654057 0.6779 -2.448 0.989 N 0.605 0.471 None gnomAD-3.1.2 3.29E-05 None None None None N None 1.20621E-04 0 0 0 0 None 0 0 0 0 0
I/T 14792 Ig-99 28 rs747654057 0.6779 -2.448 0.989 N 0.605 0.471 None gnomAD-4.0.0 6.8205E-06 None None None None N None 1.33547E-04 0 None 0 0 None 0 0 8.47965E-07 0 0
I/V 14792 Ig-99 28 None 0.1758 None 0.333 N 0.211 0.194 0.577073266457 gnomAD-4.0.0 4.8013E-06 None None None None N None 0 0 None 0 0 None 0 0 5.25002E-06 0 0
A/V 14881 Ig-100 29 rs780650251 0.6077 -0.366 0.919 N 0.651 0.334 0.492749560936 gnomAD-2.1.1 1.21E-05 None None None None N None 0 8.72E-05 None 0 0 None 0 None 0 0 0
A/V 14881 Ig-100 29 rs780650251 0.6077 -0.366 0.919 N 0.651 0.334 0.492749560936 gnomAD-4.0.0 6.37519E-06 None None None None N None 0 6.87285E-05 None 0 0 None 0 0 2.86272E-06 0 0
A/T 15059 Ig-102 29 rs144668626 0.1033 -1.245 1.0 D 0.745 0.366 None gnomAD-2.1.1 2.68029E-03 None None None None N None 1.24285E-04 7.66697E-04 None 1.069E-03 0 None 1.51703E-02 None 4E-05 1.76759E-03 2.25861E-03
A/T 15059 Ig-102 29 rs144668626 0.1033 -1.245 1.0 D 0.745 0.366 None gnomAD-3.1.2 1.58768E-03 None None None None N None 1.45019E-04 1.70805E-03 0 8.66051E-04 0 None 0 0 1.64997E-03 1.8864E-02 1.43678E-03
A/T 15059 Ig-102 29 rs144668626 0.1033 -1.245 1.0 D 0.745 0.366 None 1000 genomes 3.39457E-03 None None None None N None 0 1.4E-03 None None 0 2E-03 None None None 1.43E-02 None
A/T 15059 Ig-102 29 rs144668626 0.1033 -1.245 1.0 D 0.745 0.366 None gnomAD-4.0.0 1.86556E-03 None None None None N None 2.00278E-04 9.52222E-04 None 8.79626E-04 2.23944E-05 None 6.25645E-05 3.30688E-03 1.11359E-03 1.56624E-02 2.33974E-03
A/V 15059 Ig-102 29 rs2154212133 0.1299 None 1.0 D 0.681 0.424 0.6184965563 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/V 15059 Ig-102 29 rs2154212133 0.1299 None 1.0 D 0.681 0.424 0.6184965563 gnomAD-4.0.0 6.58562E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47388E-05 0 0
F/I 15148 Ig-103 29 None 0.2713 None 0.012 N 0.167 0.224 0.29132392195 gnomAD-4.0.0 1.59449E-06 None None None None N None 0 2.29421E-05 None 0 0 None 0 0 0 0 0
A/T 15236 Ig-104 29 None 0.3655 None 0.034 N 0.437 0.12 0.208000267992 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 5.50964E-04 None 0 0 0 0 0
V/I 15330 Ig-105 29 rs1476334999 0.1318 -0.45 0.517 N 0.524 0.23 0.56468994859 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.96E-06 0
V/I 15330 Ig-105 29 rs1476334999 0.1318 -0.45 0.517 N 0.524 0.23 0.56468994859 gnomAD-4.0.0 6.37849E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72803E-06 2.86878E-05 0
V/L 15330 Ig-105 29 rs1476334999 0.4387 None 0.349 N 0.435 0.268 0.423480098753 gnomAD-4.0.0 1.59462E-06 None None None None N None 0 0 None 0 2.78443E-05 None 0 0 0 0 0
A/S 15419 Ig-106 29 rs761783891 0.1385 -1.466 0.989 D 0.663 0.296 0.349647731962 gnomAD-2.1.1 1.04E-05 None None None None N None 0 0 None 0 1.25188E-04 None 0 None 0 0 0
A/S 15419 Ig-106 29 rs761783891 0.1385 -1.466 0.989 D 0.663 0.296 0.349647731962 gnomAD-4.0.0 7.19108E-07 None None None None N None 0 0 None 0 2.56476E-05 None 0 0 0 0 0
A/T 15419 Ig-106 29 rs761783891 0.1526 -1.457 0.977 D 0.705 0.351 0.381409048467 gnomAD-2.1.1 1.04E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.17E-05 0
A/T 15419 Ig-106 29 rs761783891 0.1526 -1.457 0.977 D 0.705 0.351 0.381409048467 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 15419 Ig-106 29 rs761783891 0.1526 -1.457 0.977 D 0.705 0.351 0.381409048467 gnomAD-4.0.0 2.39872E-05 None None None None N None 0 0 None 0 0 None 0 0 3.13583E-05 0 1.6893E-05
A/E 15597 Ig-108 30 None 0.9437 None 1.0 N 0.797 0.465 0.528811570836 gnomAD-4.0.0 4.11043E-06 None None None None N None 0 0 None 0 0 None 0 0 5.40107E-06 0 0
A/V 15597 Ig-108 30 None 0.2691 None 1.0 N 0.655 0.458 0.466655310336 gnomAD-4.0.0 6.8507E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00178E-07 0 0
P/L 16288 Ig-110 27 None 0.9806 None 1.0 D 0.847 0.725 0.865368311715 gnomAD-4.0.0 6.84763E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65909E-05
P/R 16288 Ig-110 27 rs745848084 0.9967 -0.586 1.0 D 0.86 0.743 0.818383550975 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.94E-06 0
P/R 16288 Ig-110 27 rs745848084 0.9967 -0.586 1.0 D 0.86 0.743 0.818383550975 gnomAD-4.0.0 3.42381E-06 None None None None I None 2.99491E-05 2.24105E-05 None 0 0 None 0 0 2.69978E-06 0 0
P/S 16288 Ig-110 27 rs894986526 0.99 None 1.0 D 0.851 0.738 0.592167511858 gnomAD-4.0.0 3.18848E-06 None None None None I None 0 0 None 0 2.79049E-05 None 0 0 0 0 3.03177E-05
P/R 17277 Ig-112 27 rs768086093 0.9953 -1.19 1.0 D 0.859 0.765 0.72142176282 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
P/R 17277 Ig-112 27 rs768086093 0.9953 -1.19 1.0 D 0.859 0.765 0.72142176282 gnomAD-4.0.0 4.78182E-06 None None None None N None 0 0 None 0 0 None 0 0 8.58826E-06 0 0
P/S 17702 Ig-113 26 rs1238325853 0.974 -1.205 1.0 D 0.815 0.667 0.589813230912 gnomAD-2.1.1 4.04E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/S 17702 Ig-113 26 rs1238325853 0.974 -1.205 1.0 D 0.815 0.667 0.589813230912 gnomAD-4.0.0 1.59243E-06 None None None None I None 0 2.28686E-05 None 0 0 None 0 0 0 0 0
P/S 18408 Ig-115 27 rs1400469796 0.947 None 1.0 D 0.852 0.581 0.573918482621 gnomAD-3.1.2 1.98E-05 None None None None N None 7.26E-05 0 0 0 0 None 0 0 0 0 0
P/S 18408 Ig-115 27 rs1400469796 0.947 None 1.0 D 0.852 0.581 0.573918482621 gnomAD-4.0.0 5.07684E-06 None None None None N None 8.75289E-05 0 None 0 0 None 0 0 0 0 0
P/L 18714 Ig-116 27 rs2052778665 0.9667 None 1.0 D 0.761 0.82 0.889922392587 gnomAD-3.1.2 1.32E-05 None None None None I None 2.42E-05 0 0 0 0 None 9.43E-05 0 0 0 0
P/L 18714 Ig-116 27 rs2052778665 0.9667 None 1.0 D 0.761 0.82 0.889922392587 gnomAD-4.0.0 3.10147E-06 None None None None I None 4.01059E-05 0 None 0 0 None 3.1294E-05 0 0 0 0
P/R 19416 Ig-118 26 rs1338893227 0.992 -0.718 1.0 D 0.848 0.523 0.704350777263 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
P/L 19816 Ig-119 27 rs2050451643 0.9791 None 1.0 D 0.827 0.63 0.694042930181 gnomAD-4.0.0 1.59184E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85948E-06 0 0
P/A 20108 Ig-120 29 None 0.547 None 1.0 D 0.803 0.569 0.577206278835 gnomAD-4.0.0 1.59473E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86361E-06 0 0
P/L 20108 Ig-120 29 rs751528859 0.9029 -0.644 1.0 D 0.857 0.53 0.754373025274 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
P/L 20108 Ig-120 29 rs751528859 0.9029 -0.644 1.0 D 0.857 0.53 0.754373025274 gnomAD-4.0.0 2.73906E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59973E-06 0 0
P/S 20108 Ig-120 29 None 0.948 None 1.0 D 0.853 0.593 0.602534368506 gnomAD-4.0.0 3.18946E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86361E-06 0 3.02975E-05
P/A 20506 Ig-121 28 rs762173583 0.5762 -1.656 0.767 N 0.483 0.592 0.442054744378 gnomAD-2.1.1 4.15E-06 None None None None N None 0 0 None 0 5.62E-05 None 0 None 0 0 0
P/A 20506 Ig-121 28 rs762173583 0.5762 -1.656 0.767 N 0.483 0.592 0.442054744378 gnomAD-4.0.0 4.83581E-06 None None None None N None 0 0 None 0 5.56638E-05 None 0 0 2.89032E-06 0 0
P/L 20799 Ig-122 31 None 0.9745 None 1.0 D 0.817 0.64 0.780217970496 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 20799 Ig-122 31 None 0.99 None 1.0 D 0.831 0.685 0.610141243409 gnomAD-4.0.0 3.42322E-06 None None None None N None 0 0 None 0 0 None 0 0 4.4997E-06 0 0
P/T 20799 Ig-122 31 rs1300626441 0.9888 -1.899 1.0 D 0.839 0.689 0.654251013966 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 1.11794E-04 None 0 None 0 0 0
P/T 20799 Ig-122 31 rs1300626441 0.9888 -1.899 1.0 D 0.839 0.689 0.654251013966 gnomAD-4.0.0 6.1618E-06 None None None None N None 0 0 None 0 1.2618E-04 None 0 0 0 2.32083E-05 3.31532E-05
P/A 21496 Ig-124 28 None 0.5733 None 1.0 D 0.796 0.504 0.611834235869 gnomAD-4.0.0 6.84413E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99717E-07 0 0
P/R 21496 Ig-124 28 rs764155651 0.9911 -0.708 1.0 D 0.856 0.537 0.720598499098 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/R 21496 Ig-124 28 rs764155651 0.9911 -0.708 1.0 D 0.856 0.537 0.720598499098 gnomAD-4.0.0 1.5924E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43377E-05 0
P/S 21496 Ig-124 28 rs1174418465 0.9602 -1.617 1.0 D 0.848 0.569 0.645989072673 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
P/S 21496 Ig-124 28 rs1174418465 0.9602 -1.617 1.0 D 0.848 0.569 0.645989072673 gnomAD-4.0.0 1.36883E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.32002E-05 0
P/T 21893 Ig-125 28 rs1381716551 0.9911 -1.322 1.0 D 0.871 0.696 0.74284823637 gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.99E-06 0
P/T 21893 Ig-125 28 rs1381716551 0.9911 -1.322 1.0 D 0.871 0.696 0.74284823637 gnomAD-4.0.0 1.59517E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86444E-06 0 0
P/T 22291 Ig-126 27 None 0.9698 None 1.0 D 0.807 0.729 0.629339664297 gnomAD-4.0.0 3.18653E-06 None None None None I None 0 0 None 0 0 None 0 0 5.72295E-06 0 0
P/H 23374 Ig-129 30 None 0.9942 None 1.0 D 0.777 0.691 0.79824111754 gnomAD-4.0.0 2.05417E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70038E-06 0 0
P/A 23663 Ig-130 27 rs1709593893 0.627 None 1.0 D 0.793 0.735 0.52360052443 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/A 23663 Ig-130 27 rs1709593893 0.627 None 1.0 D 0.793 0.735 0.52360052443 gnomAD-4.0.0 3.72069E-06 None None None None I None 2.67158E-05 0 None 0 0 None 0 0 0 0 6.40985E-05
P/L 23663 Ig-130 27 None 0.9218 None 1.0 D 0.817 0.762 0.698655912635 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 24458 Ig-132 28 rs1315030705 0.9326 -0.82 1.0 D 0.765 0.675 0.905105473476 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.59E-05 None 0 None 0 0 0
P/L 24458 Ig-132 28 rs1315030705 0.9326 -0.82 1.0 D 0.765 0.675 0.905105473476 gnomAD-4.0.0 2.05295E-06 None None None None N None 0 0 None 0 7.56697E-05 None 0 0 0 0 0
P/S 24458 Ig-132 28 rs1353783438 0.9793 -1.548 1.0 D 0.798 0.677 0.676464442291 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 24458 Ig-132 28 rs1353783438 0.9793 -1.548 1.0 D 0.798 0.677 0.676464442291 gnomAD-4.0.0 1.59182E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
P/S 24745 Ig-133 30 rs1708317889 0.7912 None 0.956 D 0.589 0.523 0.483521307902 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/T 25141 Ig-134 31 None 0.9684 None 1.0 D 0.858 0.757 0.621358419865 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 25540 Ig-135 27 rs541464855 0.914 -0.544 1.0 D 0.787 0.681 0.757346685873 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
P/L 25540 Ig-135 27 rs541464855 0.914 -0.544 1.0 D 0.787 0.681 0.757346685873 gnomAD-4.0.0 6.84695E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.16069E-05 0
P/Q 25540 Ig-135 27 rs541464855 0.9947 -1.491 1.0 D 0.81 0.703 0.665764703453 gnomAD-2.1.1 3.19E-05 None None None None N None 0 1.17924E-03 None 0 0 None 0 None 0 0 0
P/Q 25540 Ig-135 27 rs541464855 0.9947 -1.491 1.0 D 0.81 0.703 0.665764703453 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.9685E-04 0 0 0 None 0 0 0 0 0
P/Q 25540 Ig-135 27 rs541464855 0.9947 -1.491 1.0 D 0.81 0.703 0.665764703453 1000 genomes 1.99681E-04 None None None None N None 0 1.4E-03 None None 0 0 None None None 0 None
P/Q 25540 Ig-135 27 rs541464855 0.9947 -1.491 1.0 D 0.81 0.703 0.665764703453 gnomAD-4.0.0 4.96085E-06 None None None None N None 0 1.33565E-04 None 0 0 None 0 0 0 0 0
P/A 25827 Ig-136 30 rs1352689122 0.4141 None 1.0 D 0.775 0.653 0.567064501529 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/A 25827 Ig-136 30 rs1352689122 0.4141 None 1.0 D 0.775 0.653 0.567064501529 gnomAD-4.0.0 2.56375E-06 None None None None N None 3.38639E-05 0 None 0 0 None 0 0 0 0 0
P/H 26223 Ig-137 31 rs1706322297 0.9986 None 1.0 D 0.834 0.775 0.672866344077 gnomAD-4.0.0 1.59279E-06 None None None None N None 5.66636E-05 0 None 0 0 None 0 0 0 0 0
P/S 26223 Ig-137 31 rs777105534 0.9941 -2.348 1.0 D 0.853 0.788 0.594734989949 gnomAD-2.1.1 1.21E-05 None None None None N None 0 8.71E-05 None 0 0 None 0 None 0 0 0
P/S 26223 Ig-137 31 rs777105534 0.9941 -2.348 1.0 D 0.853 0.788 0.594734989949 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
P/S 26223 Ig-137 31 rs777105534 0.9941 -2.348 1.0 D 0.853 0.788 0.594734989949 gnomAD-4.0.0 6.81938E-06 None None None None N None 0 6.67401E-05 None 0 0 None 0 0 5.08689E-06 1.09917E-05 0
P/L 26622 Ig-138 29 rs532706350 0.9386 -0.347 1.0 D 0.827 0.685 0.866740344324 gnomAD-2.1.1 2.41E-05 None None None None N None 0 0 None 0 3.34225E-04 None 0 None 0 0 0
P/L 26622 Ig-138 29 rs532706350 0.9386 -0.347 1.0 D 0.827 0.685 0.866740344324 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 7.73694E-04 None 0 0 0 0 0
P/L 26622 Ig-138 29 rs532706350 0.9386 -0.347 1.0 D 0.827 0.685 0.866740344324 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
P/L 26622 Ig-138 29 rs532706350 0.9386 -0.347 1.0 D 0.827 0.685 0.866740344324 gnomAD-4.0.0 5.82522E-05 None None None None N None 0 0 None 0 2.07376E-03 None 0 0 0 0 1.60077E-05
P/L 26909 Ig-139 30 rs1553581878 0.8301 None 1.0 D 0.781 0.756 0.737821564749 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/L 26909 Ig-139 30 rs1553581878 0.8301 None 1.0 D 0.781 0.756 0.737821564749 gnomAD-4.0.0 6.57609E-06 None None None None I None 2.41464E-05 0 None 0 0 None 0 0 0 0 0
P/S 27305 Ig-140 28 rs1704786507 0.9763 None 1.0 D 0.839 0.623 0.595673181824 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 27305 Ig-140 28 rs1704786507 0.9763 None 1.0 D 0.839 0.623 0.595673181824 gnomAD-4.0.0 2.03004E-06 None None None None N None 0 0 None 0 0 None 0 0 2.40987E-06 0 0
A/S 27992 Ig-142 30 None 0.233 None 0.165 N 0.48 0.146 0.303781844768 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
P/L 28387 Ig-143 30 rs1415760093 0.9373 0.135 1.0 D 0.86 0.595 0.803546519037 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
P/L 28387 Ig-143 30 rs1415760093 0.9373 0.135 1.0 D 0.86 0.595 0.803546519037 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 28387 Ig-143 30 rs1415760093 0.9373 0.135 1.0 D 0.86 0.595 0.803546519037 gnomAD-4.0.0 6.40612E-06 None None None None I None 0 0 None 0 0 None 0 0 9.57148E-06 0 2.84398E-05
P/S 28387 Ig-143 30 rs561992231 0.9892 -1.57 1.0 D 0.856 0.63 0.6478668012 gnomAD-2.1.1 4.03E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/S 28387 Ig-143 30 rs561992231 0.9892 -1.57 1.0 D 0.856 0.63 0.6478668012 gnomAD-3.1.2 1.97E-05 None None None None I None 7.25E-05 0 0 0 0 None 0 0 0 0 0
P/S 28387 Ig-143 30 rs561992231 0.9892 -1.57 1.0 D 0.856 0.63 0.6478668012 1000 genomes 1.99681E-04 None None None None I None 8E-04 0 None None 0 0 None None None 0 None
P/S 28387 Ig-143 30 rs561992231 0.9892 -1.57 1.0 D 0.856 0.63 0.6478668012 gnomAD-4.0.0 7.10468E-06 None None None None I None 1.22151E-04 0 None 0 0 None 0 0 0 0 0
P/A 28784 Ig-144 30 rs748783837 0.7435 -1.912 1.0 D 0.776 0.554 0.587872879989 gnomAD-2.1.1 4.13E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.06E-06 0
P/A 28784 Ig-144 30 rs748783837 0.7435 -1.912 1.0 D 0.776 0.554 0.587872879989 gnomAD-4.0.0 1.61046E-06 None None None None N None 0 0 None 0 0 None 0 0 2.88366E-06 0 0
P/L 28784 Ig-144 30 None 0.944 None 1.0 D 0.827 0.57 0.821040667405 gnomAD-4.0.0 1.37608E-06 None None None None N None 0 0 None 0 0 None 0 0 9.02348E-07 1.17617E-05 0
P/R 28784 Ig-144 30 None 0.992 None 1.0 D 0.842 0.573 0.701705663459 gnomAD-4.0.0 2.75215E-06 None None None None N None 0 0 None 0 0 None 0 0 3.60939E-06 0 0
P/A 29074 Ig-145 30 rs761409208 0.6324 -0.811 1.0 D 0.815 0.658 None gnomAD-2.1.1 2.5E-05 None None None None I None 2.89376E-04 0 None 0 0 None 0 None 0 0 0
P/A 29074 Ig-145 30 rs761409208 0.6324 -0.811 1.0 D 0.815 0.658 None gnomAD-3.1.2 6.57E-05 None None None None I None 2.4122E-04 0 0 0 0 None 0 0 0 0 0
P/A 29074 Ig-145 30 rs761409208 0.6324 -0.811 1.0 D 0.815 0.658 None gnomAD-4.0.0 1.05345E-05 None None None None I None 2.2686E-04 0 None 0 0 None 0 0 0 0 0
P/R 29869 Ig-147 28 rs770203238 0.9882 None 1.0 D 0.859 0.741 0.68971630469 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/R 29869 Ig-147 28 rs770203238 0.9882 None 1.0 D 0.859 0.741 0.68971630469 gnomAD-4.0.0 6.56953E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46972E-05 0 0
P/S 30161 Ig-148 30 None 0.9476 None 1.0 D 0.84 0.677 0.627239104411 gnomAD-4.0.0 1.63395E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.47654E-05 0
P/L 30556 Ig-149 25 None 0.9354 None 1.0 D 0.757 0.768 0.877019509546 gnomAD-4.0.0 1.36842E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79897E-06 0 0
P/L 30955 Ig-150 29 rs1371353912 0.9179 -0.622 1.0 D 0.779 0.723 0.867300734482 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
P/L 30955 Ig-150 29 rs1371353912 0.9179 -0.622 1.0 D 0.779 0.723 0.867300734482 gnomAD-4.0.0 1.59213E-06 None None None None N None 0 0 None 0 2.77346E-05 None 0 0 0 0 0
P/T 30955 Ig-150 29 rs1323009434 0.9561 None 1.0 D 0.794 0.771 0.752604504585 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 30955 Ig-150 29 rs1323009434 0.9561 None 1.0 D 0.794 0.771 0.752604504585 gnomAD-4.0.0 3.84489E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17872E-06 0 0
P/L 31245 Ig-151 28 rs760438860 0.8033 -0.522 1.0 D 0.849 0.602 None gnomAD-2.1.1 2.14E-05 None None None None N None 2.06714E-04 0 None 0 0 None 3.27E-05 None 0 0 0
P/L 31245 Ig-151 28 rs760438860 0.8033 -0.522 1.0 D 0.849 0.602 None gnomAD-3.1.2 2.63E-05 None None None None N None 9.66E-05 0 0 0 0 None 0 0 0 0 0
P/L 31245 Ig-151 28 rs760438860 0.8033 -0.522 1.0 D 0.849 0.602 None gnomAD-4.0.0 3.71826E-06 None None None None N None 6.67771E-05 0 None 0 0 None 0 0 0 1.09791E-05 0
P/R 31245 Ig-151 28 rs760438860 0.9708 -0.925 1.0 D 0.861 0.647 0.670756170047 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/R 31245 Ig-151 28 rs760438860 0.9708 -0.925 1.0 D 0.861 0.647 0.670756170047 gnomAD-4.0.0 2.05257E-06 None None None None N None 5.97514E-05 0 None 3.82702E-05 0 None 0 0 0 0 0
P/S 31245 Ig-151 28 None 0.9064 None 1.0 D 0.847 0.59 0.569844293628 gnomAD-4.0.0 2.05258E-06 None None None None N None 0 0 None 0 0 None 0 0 2.6983E-06 0 0
P/T 31245 Ig-151 28 None 0.8879 None 1.0 D 0.855 0.614 0.623711697247 gnomAD-4.0.0 6.84192E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99434E-07 0 0
P/A 31645 Ig-152 25 None 0.8774 None 1.0 D 0.779 0.656 0.582701273649 gnomAD-4.0.0 6.84223E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99488E-07 0 0
P/H 31645 Ig-152 25 rs1347498882 0.9971 -1.903 1.0 D 0.781 0.683 0.697854085041 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/H 31645 Ig-152 25 rs1347498882 0.9971 -1.903 1.0 D 0.781 0.683 0.697854085041 gnomAD-4.0.0 4.77404E-06 None None None None N None 0 4.5731E-05 None 0 0 None 0 0 2.85848E-06 0 0
P/L 31645 Ig-152 25 None 0.9427 None 1.0 D 0.81 0.632 0.769528849365 gnomAD-4.0.0 1.59135E-06 None None None None N None 0 0 None 0 2.77346E-05 None 0 0 0 0 0
P/S 31645 Ig-152 25 rs770465865 0.9884 -2.146 1.0 D 0.827 0.701 None gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.56E-05 0
P/S 31645 Ig-152 25 rs770465865 0.9884 -2.146 1.0 D 0.827 0.701 None gnomAD-4.0.0 8.21067E-06 None None None None N None 0 0 None 0 0 None 0 0 1.07939E-05 0 0
P/T 31645 Ig-152 25 rs770465865 0.9771 -1.928 1.0 D 0.833 0.674 0.650902943696 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/T 31645 Ig-152 25 rs770465865 0.9771 -1.928 1.0 D 0.833 0.674 0.650902943696 gnomAD-4.0.0 6.84223E-07 None None None None N None 0 2.23634E-05 None 0 0 None 0 0 0 0 0
P/L 32044 Ig-153 28 None 0.8895 None 1.0 D 0.841 0.718 0.808182242251 gnomAD-4.0.0 2.40065E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 7.32654E-05
P/L 32336 Ig-154 30 rs745496890 0.7443 -0.603 1.0 D 0.866 0.618 0.769516625955 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 2.22767E-04 None 0 None 0 0 0
P/L 32336 Ig-154 30 rs745496890 0.7443 -0.603 1.0 D 0.866 0.618 0.769516625955 gnomAD-4.0.0 3.42096E-06 None None None None N None 0 0 None 0 1.00766E-04 None 0 0 0 0 1.65651E-05
P/Q 32734 Ig-155 27 rs1559091870 0.9945 None 0.999 D 0.79 0.553 0.633466640759 gnomAD-4.0.0 2.40067E-06 None None None None I None 0 0 None 0 0 None 0 0 2.62503E-06 0 0
P/S 33130 Ig-156 30 rs1692281859 0.9643 None 1.0 D 0.821 0.647 0.637981554935 gnomAD-4.0.0 1.59158E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43332E-05 0
P/S 33226 Ig-157 24 None 0.9638 None 1.0 D 0.785 0.709 0.67965922819 gnomAD-4.0.0 1.59142E-06 None None None None N None 0 0 None 0 2.77362E-05 None 0 0 0 0 0
P/S 33525 Ig-158 30 None 0.9856 None 0.992 D 0.765 0.664 0.629215704067 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92976E-04 None 0 0 0 0 0
P/S 33525 Ig-158 30 None 0.9856 None 0.992 D 0.765 0.664 0.629215704067 gnomAD-4.0.0 2.56307E-06 None None None None N None 0 0 None 0 2.42589E-05 None 0 0 0 1.34045E-05 0
T/S 34166 Ig-160 30 None 0.4611 None 0.999 N 0.624 0.427 0.394079506076 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
P/T 34287 Ig-161 30 None 0.96 None 1.0 D 0.837 0.776 0.587327121794 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/A 34392 Ig-162 30 None 0.8292 None 1.0 D 0.776 0.724 0.570999777189 gnomAD-4.0.0 6.84193E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15939E-05 0
P/S 34392 Ig-162 30 rs767698514 0.9812 -2.545 1.0 D 0.818 0.76 0.606774948416 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 34392 Ig-162 30 rs767698514 0.9812 -2.545 1.0 D 0.818 0.76 0.606774948416 gnomAD-4.0.0 2.05258E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.47818E-05 0
P/T 34392 Ig-162 30 rs767698514 0.9684 None 1.0 D 0.828 0.751 0.640634255683 gnomAD-4.0.0 6.84193E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99429E-07 0 0
A/V 34971 Ig-163 30 rs1419052992 0.6775 -0.729 0.904 N 0.604 0.323 0.40417439687 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
A/V 34971 Ig-163 30 rs1419052992 0.6775 -0.729 0.904 N 0.604 0.323 0.40417439687 gnomAD-3.1.2 3.94E-05 None None None None N None 7.24E-05 1.30873E-04 0 0 0 None 0 0 0 0 4.78011E-04
A/V 34971 Ig-163 30 rs1419052992 0.6775 -0.729 0.904 N 0.604 0.323 0.40417439687 gnomAD-4.0.0 5.57668E-06 None None None None N None 8.00876E-05 3.33311E-05 None 0 0 None 0 0 0 0 1.60087E-05
P/A 35158 Ig-164 30 rs758006957 0.6936 -1.883 0.999 D 0.804 0.644 0.452834868696 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
P/A 35158 Ig-164 30 rs758006957 0.6936 -1.883 0.999 D 0.804 0.644 0.452834868696 gnomAD-4.0.0 7.52548E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99392E-06 0 1.65634E-05
P/Q 35158 Ig-164 30 rs749980197 0.9818 -2.006 1.0 D 0.836 0.645 0.683264030212 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
P/Q 35158 Ig-164 30 rs749980197 0.9818 -2.006 1.0 D 0.836 0.645 0.683264030212 gnomAD-4.0.0 1.59087E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8575E-06 0 0
P/T 35158 Ig-164 30 rs758006957 0.9291 -2.149 1.0 D 0.843 0.65 0.648683320972 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
P/T 35158 Ig-164 30 rs758006957 0.9291 -2.149 1.0 D 0.843 0.65 0.648683320972 gnomAD-4.0.0 6.84135E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99392E-07 0 0
K/T 35315 Ig-165 30 None 0.2237 None 0.549 N 0.637 0.301 0.318252033908 gnomAD-4.0.0 1.59086E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/L 35449 Ig-166 30 rs1688512562 0.4795 None 1.0 D 0.847 0.735 0.673546118213 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
P/L 35449 Ig-166 30 rs1688512562 0.4795 None 1.0 D 0.847 0.735 0.673546118213 gnomAD-4.0.0 6.56538E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.07211E-04 0
P/Q 35449 Ig-166 30 rs1688512562 0.8725 None 1.0 D 0.864 0.747 0.539792608675 gnomAD-4.0.0 6.43209E-06 None None None None N None 0 0 None 0 1.11179E-04 None 0 0 0 0 0
T/A 35634 Ig-167 28 None 0.1117 None 0.041 N 0.351 0.136 0.143124449307 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/T 35731 Ig-168 30 None 0.846 None 0.998 D 0.788 0.758 0.741916266591 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
P/L 35926 Ig-169 30 rs749774302 0.8642 -0.677 1.0 N 0.807 0.555 0.827018898375 gnomAD-2.1.1 4.02E-06 None None None -1.241(OBSL1) -1.024(OBSCN) N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
P/L 35926 Ig-169 30 rs749774302 0.8642 -0.677 1.0 N 0.807 0.555 0.827018898375 gnomAD-4.0.0 3.18213E-06 None None None -1.241(OBSL1) -1.024(OBSCN) N None 0 0 None 0 0 None 0 0 5.71553E-06 0 0
P/R 35926 Ig-169 30 rs749774302 0.9701 None 1.0 D 0.798 0.612 0.796347251703 gnomAD-4.0.0 1.59106E-06 None None None -1.45(OBSL1) -1.08(OBSCN) N None 0 0 None 0 0 None 0 0 2.85776E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.