Structural position:
- Domain Type: Ig
- Aligned Position: 48
- Secondary Structure Element: e
- Secondary Structure Region: β-strand C
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F/I | 137 |
Ig-2 |
34 | None | 0.9621 | None | 1.0 | N | 0.828 | 0.648 | 0.594903367923 | gnomAD-4.0.0 | 1.5905E-06 | None | None | None | -1.062(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85647E-06 | 0 | 0 |
| F/L | 137 |
Ig-2 |
34 | rs1482023535 |
0.9978 | -0.835 | 1.0 | N | 0.821 | 0.623 | 0.629031148641 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | -1.062(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.8E-06 | 0 |
| F/L | 137 |
Ig-2 |
34 | rs1482023535 |
0.9978 | -0.835 | 1.0 | N | 0.821 | 0.623 | 0.629031148641 | gnomAD-4.0.0 | 1.5905E-06 | None | None | None | -1.062(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0217E-05 |
| W/R | 976 |
Ig-3 |
34 | rs267607155 |
0.9999 | -2.071 | 1.0 | D | 0.824 | 0.96 | 0.953454579525 |
Gerull (2002)
Herman (2012)
| None |
DCM
|
het / comp het with R21201* | None | None | N | Linkage analysis in single DCM family, incomplete penetrance (n = 15, 11 affected, 4 unaffected carriers (total 35)) | None | None | None | None | None | None | None | None | None | None | None |
| W/R | 1589 |
Ig-7 |
34 | None | 0.9998 | None | 1.0 | D | 0.891 | 0.923 | 0.940765596123 | gnomAD-4.0.0 | 1.59062E-06 | None | None | None | None | N | None | 5.65419E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/G | 1874 |
Ig-9 |
34 | rs2092211950 |
0.9911 | None | 1.0 | D | 0.779 | 0.964 | 0.92289228119 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/G | 1874 |
Ig-9 |
34 | rs2092211950 |
0.9911 | None | 1.0 | D | 0.779 | 0.964 | 0.92289228119 | gnomAD-4.0.0 | 6.56927E-06 | None | None | None | None | N | None | 2.41278E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 1874 |
Ig-9 |
34 | None | 0.9997 | None | 1.0 | D | 0.831 | 0.956 | 0.936407739719 | gnomAD-4.0.0 | 1.59051E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85656E-06 | 0 | 0 |
| W/S | 1874 |
Ig-9 |
34 | None | 0.998 | None | 1.0 | D | 0.813 | 0.954 | 0.964158111835 | gnomAD-4.0.0 | 3.18105E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86549E-05 | 0 |
| W/L | 2111 |
Ig-10 |
34 | rs2092127553 |
0.9632 | None | 1.0 | D | 0.781 | 0.935 | 0.910078474493 | gnomAD-4.0.0 | 1.59083E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 0 | 0 | 0 |
| W/R | 2299 |
Ig-12 |
33 | rs145585333 |
0.9995 | -1.943 | 1.0 | D | 0.868 | 0.938 | 0.927908074176 | gnomAD-2.1.1 | 1.77E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.88E-05 | 0 |
| W/R | 2299 |
Ig-12 |
33 | rs145585333 |
0.9995 | -1.943 | 1.0 | D | 0.868 | 0.938 | 0.927908074176 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| W/R | 2299 |
Ig-12 |
33 | rs145585333 |
0.9995 | -1.943 | 1.0 | D | 0.868 | 0.938 | 0.927908074176 | gnomAD-4.0.0 | 3.47001E-05 | None | None | None | None | N | None | 1.33551E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.6612E-05 | 0 | 0 |
| W/L | 2652 |
Ig-16 |
32 | None | 0.9232 | None | 1.0 | D | 0.82 | 0.822 | 0.963012162132 | gnomAD-4.0.0 | 1.59066E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| W/C | 2827 |
Ig-18 |
33 | None | 0.9988 | None | 1.0 | D | 0.811 | 0.938 | 0.921173998916 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/L | 2827 |
Ig-18 |
33 | None | 0.9633 | None | 1.0 | D | 0.806 | 0.882 | 0.955322292483 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| W/R | 2914 |
Ig-19 |
33 | None | 0.9998 | None | 1.0 | D | 0.865 | 0.975 | 0.931936721434 | gnomAD-4.0.0 | 1.59049E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| W/S | 3090 |
Ig-21 |
33 | rs761150662 |
0.9992 | -3.112 | 0.971 | D | 0.852 | 0.899 | 0.952240869178 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| W/S | 3090 |
Ig-21 |
33 | rs761150662 |
0.9992 | -3.112 | 0.971 | D | 0.852 | 0.899 | 0.952240869178 | gnomAD-4.0.0 | 3.18109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
| W/C | 3179 |
Ig-22 |
33 | rs1415326228 |
0.9985 | None | 1.0 | D | 0.83 | 0.887 | 0.911953112043 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92382E-04 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 3179 |
Ig-22 |
33 | rs1415326228 |
0.9985 | None | 1.0 | D | 0.83 | 0.887 | 0.911953112043 | gnomAD-4.0.0 | 2.47842E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22856E-05 | None | 0 | 0 | 2.54238E-06 | 0 | 0 |
| W/L | 3179 |
Ig-22 |
33 | rs1561183313 |
0.9658 | None | 0.999 | D | 0.816 | 0.877 | 0.949931909184 | gnomAD-4.0.0 | 3.18126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.8216E-04 | 0 | 0 | 0 |
| W/C | 3272 |
Ig-23 |
34 | rs1296156744 |
0.9957 | -1.042 | 1.0 | D | 0.796 | 0.933 | 0.861801042988 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 1.17924E-03 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 3272 |
Ig-23 |
34 | rs1296156744 |
0.9957 | -1.042 | 1.0 | D | 0.796 | 0.933 | 0.861801042988 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 3272 |
Ig-23 |
34 | rs1296156744 |
0.9957 | -1.042 | 1.0 | D | 0.796 | 0.933 | 0.861801042988 | gnomAD-4.0.0 | 6.57255E-06 | None | None | None | None | N | None | 0 | 6.5505E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 3272 |
Ig-23 |
34 | None | 0.9994 | None | 1.0 | D | 0.878 | 0.952 | 0.932409099026 | gnomAD-4.0.0 | 2.05222E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6979E-06 | 0 | 0 |
| W/C | 3498 |
Ig-25 |
34 | None | 0.9959 | None | None | None | None | 0.763 | None | gnomAD-4.0.0 | 6.84182E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9945E-07 | 0 | 0 |
| W/C | 3693 |
Ig-26 |
34 | rs1418383174 |
0.9898 | -1.722 | None | None | None | 0.802 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| W/C | 3693 |
Ig-26 |
34 | rs1418383174 |
0.9898 | -1.722 | None | None | None | 0.802 | None | gnomAD-4.0.0 | 4.10529E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39667E-06 | 0 | 0 |
| W/C | 3971 |
Ig-28 |
34 | rs749961489 |
0.9831 | -0.975 | 1.0 | D | 0.769 | 0.751 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| W/C | 3971 |
Ig-28 |
34 | rs749961489 |
0.9831 | -0.975 | 1.0 | D | 0.769 | 0.751 | None | gnomAD-4.0.0 | 6.84174E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99429E-07 | 0 | 0 |
| W/R | 3971 |
Ig-28 |
34 | None | 0.997 | None | 1.0 | D | 0.858 | 0.883 | None | gnomAD-4.0.0 | 3.42087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49715E-06 | 0 | 0 |
| W/C | 4637 |
Ig-29 |
32 | None | 0.9725 | None | 1.0 | D | 0.825 | 0.888 | None | gnomAD-4.0.0 | 1.59159E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85853E-06 | 0 | 0 |
| W/L | 4637 |
Ig-29 |
32 | rs1362989287 |
0.8247 | -2.223 | 1.0 | D | 0.822 | 0.847 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/L | 4637 |
Ig-29 |
32 | rs1362989287 |
0.8247 | -2.223 | 1.0 | D | 0.822 | 0.847 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.3101E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/L | 4637 |
Ig-29 |
32 | rs1362989287 |
0.8247 | -2.223 | 1.0 | D | 0.822 | 0.847 | None | gnomAD-4.0.0 | 3.84414E-06 | None | None | None | None | N | None | 0 | 5.08613E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 4733 |
Ig-30 |
34 | None | 0.998 | None | 1.0 | D | 0.837 | 0.912 | 0.838866915185 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| W/S | 4828 |
Ig-31 |
34 | rs747830811 |
0.9828 | -3.291 | 1.0 | D | 0.839 | 0.866 | 0.969610535463 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| W/R | 4921 |
Ig-32 |
34 | rs769723198 |
0.9975 | -1.862 | 1.0 | D | 0.875 | 0.93 | 0.951808353149 | gnomAD-2.1.1 | 7.14E-06 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/R | 4921 |
Ig-32 |
34 | rs769723198 |
0.9975 | -1.862 | 1.0 | D | 0.875 | 0.93 | 0.951808353149 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 4921 |
Ig-32 |
34 | rs769723198 |
0.9975 | -1.862 | 1.0 | D | 0.875 | 0.93 | 0.951808353149 | gnomAD-4.0.0 | 1.8591E-06 | None | None | None | None | N | None | 2.66916E-05 | 1.66711E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/L | 5294 |
Ig-36 |
34 | None | 0.7642 | None | 1.0 | D | 0.837 | 0.868 | 0.964309650005 | gnomAD-4.0.0 | 6.36511E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.14333E-05 | 0 | 0 |
| W/R | 5483 |
Ig-38 |
34 | rs72648938 |
0.9984 | None | 0.999 | D | 0.865 | 0.963 | 0.968585133873 | gnomAD-4.0.0 | 1.36861E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79904E-06 | 0 | 0 |
| W/R | 5577 |
Ig-39 |
35 | rs1194619992 |
0.9978 | -2.138 | 1.0 | D | 0.861 | 0.895 | 0.956656731583 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/R | 5577 |
Ig-39 |
35 | rs1194619992 |
0.9978 | -2.138 | 1.0 | D | 0.861 | 0.895 | 0.956656731583 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 5577 |
Ig-39 |
35 | rs1194619992 |
0.9978 | -2.138 | 1.0 | D | 0.861 | 0.895 | 0.956656731583 | gnomAD-4.0.0 | 1.8591E-06 | None | None | None | None | N | None | 2.66987E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47614E-07 | 0 | 0 |
| W/C | 5670 |
Ig-40 |
34 | rs759141317 |
0.9499 | -1.498 | 0.077 | D | 0.701 | 0.624 | 0.877831071711 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| W/C | 5670 |
Ig-40 |
34 | rs759141317 |
0.9499 | -1.498 | 0.077 | D | 0.701 | 0.624 | 0.877831071711 | gnomAD-4.0.0 | 1.59135E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8585E-06 | 0 | 0 |
| W/R | 5763 |
Ig-41 |
34 | rs897659304 |
0.9994 | None | 0.999 | D | 0.866 | 0.951 | 0.939118346112 | gnomAD-4.0.0 | 1.59156E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85847E-06 | 0 | 0 |
| W/R | 5856 |
Ig-42 |
34 | None | 0.9988 | None | 1.0 | D | 0.854 | 0.958 | 0.940182123992 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 5952 |
Ig-43 |
34 | None | 0.9998 | None | 0.928 | D | 0.874 | 0.889 | 0.937825855988 | gnomAD-4.0.0 | 1.59159E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85892E-06 | 0 | 0 |
| W/S | 5952 |
Ig-43 |
34 | rs2080292615 |
0.9987 | None | 0.864 | D | 0.867 | 0.885 | 0.967651819318 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 5952 |
Ig-43 |
34 | rs2080292615 |
0.9987 | None | 0.864 | D | 0.867 | 0.885 | 0.967651819318 | gnomAD-4.0.0 | 6.57583E-06 | None | None | None | None | N | None | 2.41406E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 6045 |
Ig-44 |
34 | rs1463290209 |
0.9957 | -1.263 | 1.0 | D | 0.777 | 0.906 | 0.756221128592 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.67001E-04 |
| W/C | 6045 |
Ig-44 |
34 | rs1463290209 |
0.9957 | -1.263 | 1.0 | D | 0.777 | 0.906 | 0.756221128592 | gnomAD-4.0.0 | 6.84509E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99659E-07 | 0 | 0 |
| W/L | 6418 |
Ig-48 |
34 | rs1255477670 |
0.8725 | -1.715 | 1.0 | D | 0.808 | 0.797 | 0.961067375456 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/L | 6418 |
Ig-48 |
34 | rs1255477670 |
0.8725 | -1.715 | 1.0 | D | 0.808 | 0.797 | 0.961067375456 | gnomAD-4.0.0 | 1.59231E-06 | None | None | None | None | N | None | 0 | 2.28927E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 6514 |
Ig-49 |
34 | None | 0.9908 | None | 0.056 | D | 0.76 | 0.889 | 0.887458683018 | gnomAD-4.0.0 | 4.79107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.2976E-06 | 0 | 0 |
| W/L | 6514 |
Ig-49 |
34 | rs760007747 |
0.8411 | -1.991 | 0.805 | D | 0.802 | 0.781 | None | gnomAD-2.1.1 | 2.51E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.71E-05 | 0 |
| W/L | 6514 |
Ig-49 |
34 | rs760007747 |
0.8411 | -1.991 | 0.805 | D | 0.802 | 0.781 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 8.82E-05 | 0 | 0 |
| W/L | 6514 |
Ig-49 |
34 | rs760007747 |
0.8411 | -1.991 | 0.805 | D | 0.802 | 0.781 | None | gnomAD-4.0.0 | 5.20729E-05 | None | None | None | None | N | None | 2.67144E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 6.69755E-05 | 0 | 4.80615E-05 |
| W/R | 6607 |
Ig-50 |
34 | None | 0.9982 | None | 1.0 | D | 0.871 | 0.919 | 0.939463572141 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/C | 6701 |
Ig-51 |
35 | None | 0.9947 | None | 1.0 | D | 0.777 | 0.734 | 0.88842533597 | gnomAD-4.0.0 | 1.59267E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43361E-05 | 0 |
| W/C | 6981 |
Ig-54 |
34 | rs746471698 |
0.9954 | -0.303 | 1.0 | D | 0.821 | 0.878 | 0.925011788365 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22891E-04 | None | 0 | None | 0 | 0 | 0 |
| W/C | 6981 |
Ig-54 |
34 | rs746471698 |
0.9954 | -0.303 | 1.0 | D | 0.821 | 0.878 | 0.925011788365 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 6981 |
Ig-54 |
34 | rs746471698 |
0.9954 | -0.303 | 1.0 | D | 0.821 | 0.878 | 0.925011788365 | gnomAD-4.0.0 | 2.47937E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.91544E-05 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 7170 |
Ig-56 |
34 | rs755516123 |
0.9969 | -1.937 | 1.0 | D | 0.887 | 0.915 | 0.954065469025 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| W/R | 7170 |
Ig-56 |
34 | rs755516123 |
0.9969 | -1.937 | 1.0 | D | 0.887 | 0.915 | 0.954065469025 | gnomAD-4.0.0 | 3.18516E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72004E-06 | 0 | 0 |
| W/C | 7263 |
Ig-57 |
34 | rs377544260 |
0.995 | -1.964 | 1.0 | D | 0.821 | 0.76 | 0.920131777592 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 1.65618E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 7263 |
Ig-57 |
34 | rs377544260 |
0.995 | -1.964 | 1.0 | D | 0.821 | 0.76 | 0.920131777592 | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 2.41406E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 7263 |
Ig-57 |
34 | rs377544260 |
0.995 | -1.964 | 1.0 | D | 0.821 | 0.76 | 0.920131777592 | gnomAD-4.0.0 | 8.67755E-06 | None | None | None | None | N | None | 1.86981E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/G | 7263 |
Ig-57 |
34 | None | 0.9824 | None | 0.217 | D | 0.692 | 0.861 | 0.911182896716 | gnomAD-4.0.0 | 1.36864E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31911E-05 | 0 |
| W/C | 7356 |
Ig-58 |
34 | rs908134644 |
0.9932 | None | 1.0 | D | 0.828 | 0.763 | 0.921398576477 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| W/C | 7356 |
Ig-58 |
34 | rs908134644 |
0.9932 | None | 1.0 | D | 0.828 | 0.763 | 0.921398576477 | gnomAD-4.0.0 | 6.41037E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.19724E-05 | 0 | 0 |
| W/L | 7356 |
Ig-58 |
34 | None | 0.9182 | None | 0.999 | D | 0.811 | 0.771 | 0.960035691554 | gnomAD-4.0.0 | 1.59246E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86007E-06 | 0 | 0 |
| W/C | 7548 |
Ig-60 |
34 | rs775685171 |
0.9982 | -1.771 | 1.0 | D | 0.757 | 0.727 | 0.775822701225 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| W/L | 7548 |
Ig-60 |
34 | None | 0.9399 | None | 1.0 | D | 0.797 | 0.716 | 0.947208517384 | gnomAD-4.0.0 | 6.84417E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99705E-07 | 0 | 0 |
| W/G | 7735 |
Ig-62 |
34 | None | 0.9886 | None | 1.0 | D | 0.852 | 0.933 | 0.934736624955 | gnomAD-4.0.0 | 6.84367E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99614E-07 | 0 | 0 |
| W/S | 7735 |
Ig-62 |
34 | rs1031182598 |
0.9965 | -3.077 | 1.0 | D | 0.88 | 0.901 | 0.972874527138 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| W/S | 7735 |
Ig-62 |
34 | rs1031182598 |
0.9965 | -3.077 | 1.0 | D | 0.88 | 0.901 | 0.972874527138 | gnomAD-4.0.0 | 3.18447E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86681E-05 | 0 |
| W/L | 7828 |
Ig-63 |
34 | rs750697689 |
0.9239 | -2.146 | 1.0 | D | 0.854 | 0.83 | 0.962728113367 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 8.9E-06 | 0 |
| W/L | 7828 |
Ig-63 |
34 | rs750697689 |
0.9239 | -2.146 | 1.0 | D | 0.854 | 0.83 | 0.962728113367 | gnomAD-4.0.0 | 3.18293E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 2.85871E-06 | 0 | 0 |
| W/C | 7922 |
Ig-64 |
34 | rs1342595109 |
0.9959 | -0.389 | 1.0 | D | 0.765 | 0.823 | 0.922666358854 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 7922 |
Ig-64 |
34 | rs1342595109 |
0.9959 | -0.389 | 1.0 | D | 0.765 | 0.823 | 0.922666358854 | gnomAD-4.0.0 | 2.05274E-06 | None | None | None | None | N | None | 0 | 2.23614E-05 | None | 0 | 0 | None | 0 | 1.73491E-04 | 8.99528E-07 | 0 | 0 |
| W/R | 7922 |
Ig-64 |
34 | rs1049106432 |
0.9989 | -1.593 | 1.0 | D | 0.849 | 0.939 | 0.940907279294 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| W/R | 7922 |
Ig-64 |
34 | rs1049106432 |
0.9989 | -1.593 | 1.0 | D | 0.849 | 0.939 | 0.940907279294 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| W/R | 7922 |
Ig-64 |
34 | rs1049106432 |
0.9989 | -1.593 | 1.0 | D | 0.849 | 0.939 | 0.940907279294 | gnomAD-4.0.0 | 6.84249E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99528E-07 | 0 | 0 |
| W/C | 8297 |
Ig-68 |
34 | rs727504205 |
0.9969 | None | 1.0 | D | 0.871 | 0.788 | 0.930896607594 | gnomAD-4.0.0 | 2.05508E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69859E-06 | 0 | 0 |
| W/L | 8393 |
Ig-69 |
34 | None | 0.9394 | None | 1.0 | D | 0.806 | 0.721 | 0.944499737478 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 1.01626E-03 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 8489 |
Ig-70 |
34 | None | 0.9991 | None | 1.0 | D | 0.81 | 0.909 | 0.764209397972 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| W/R | 8489 |
Ig-70 |
34 | rs1478462166 |
0.9997 | -2.171 | 1.0 | D | 0.883 | 0.936 | 0.954361339775 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| W/R | 8583 |
Ig-71 |
35 | None | 0.9987 | None | 1.0 | D | 0.889 | 0.935 | 0.942336615409 | gnomAD-4.0.0 | 2.05362E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69924E-06 | 0 | 0 |
| W/R | 8676 |
Ig-72 |
34 | None | 0.9989 | None | 1.0 | D | 0.888 | 0.928 | 0.94125591744 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/G | 8769 |
Ig-73 |
34 | rs779847107 |
0.9255 | -2.495 | 1.0 | D | 0.817 | 0.916 | 0.929467472191 | gnomAD-4.0.0 | 4.7901E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29681E-06 | 0 | 0 |
| W/R | 8863 |
Ig-74 |
34 | rs1298764368 |
0.998 | -1.894 | 1.0 | D | 0.835 | 0.935 | 0.945307626599 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| W/R | 8863 |
Ig-74 |
34 | rs1298764368 |
0.998 | -1.894 | 1.0 | D | 0.835 | 0.935 | 0.945307626599 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 8863 |
Ig-74 |
34 | rs1298764368 |
0.998 | -1.894 | 1.0 | D | 0.835 | 0.935 | 0.945307626599 | gnomAD-4.0.0 | 1.5917E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85879E-06 | 0 | 0 |
| W/L | 8959 |
Ig-75 |
34 | None | 0.9123 | None | 0.477 | D | 0.819 | 0.755 | 0.942273410946 | gnomAD-4.0.0 | 6.84813E-07 | None | None | None | None | N | None | 2.98864E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 9052 |
Ig-76 |
34 | None | 0.9865 | None | 1.0 | D | 0.801 | 0.938 | 0.921798978456 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/L | 9052 |
Ig-76 |
34 | None | 0.8771 | None | 1.0 | D | 0.822 | 0.924 | 0.956461217238 | gnomAD-4.0.0 | 1.36853E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79901E-06 | 0 | 0 |
| W/S | 9052 |
Ig-76 |
34 | rs769663130 |
0.9708 | -2.906 | 1.0 | D | 0.851 | 0.872 | 0.967615550514 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| W/S | 9052 |
Ig-76 |
34 | rs769663130 |
0.9708 | -2.906 | 1.0 | D | 0.851 | 0.872 | 0.967615550514 | gnomAD-4.0.0 | 3.42133E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49752E-06 | 0 | 0 |
| W/C | 9145 |
Ig-77 |
34 | rs1284458172 |
0.9961 | None | 1.0 | D | 0.757 | 0.823 | 0.746058035586 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 9145 |
Ig-77 |
34 | rs1284458172 |
0.9961 | None | 1.0 | D | 0.757 | 0.823 | 0.746058035586 | gnomAD-4.0.0 | 1.59126E-06 | None | None | None | None | N | None | 5.65547E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 9334 |
Ig-79 |
34 | rs555411623 |
0.9964 | -1.282 | 1.0 | None | 0.74 | 0.828 | 0.929143421364 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 9334 |
Ig-79 |
34 | rs555411623 |
0.9964 | -1.282 | 1.0 | None | 0.74 | 0.828 | 0.929143421364 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| W/C | 9334 |
Ig-79 |
34 | rs555411623 |
0.9964 | -1.282 | 1.0 | None | 0.74 | 0.828 | 0.929143421364 | gnomAD-4.0.0 | 6.57168E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93349E-04 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 9334 |
Ig-79 |
34 | None | 0.9932 | None | 1.0 | None | 0.811 | 0.811 | 0.968639366473 | gnomAD-4.0.0 | 6.84175E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99447E-07 | 0 | 0 |
| W/G | 9527 |
Ig-81 |
35 | None | 0.9718 | None | 1.0 | None | 0.788 | 0.952 | 0.930020937758 | gnomAD-4.0.0 | 1.59106E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| W/L | 9623 |
Ig-82 |
34 | None | 0.9147 | None | 1.0 | None | 0.784 | 0.912 | 0.950575755727 | gnomAD-4.0.0 | 6.8417E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99426E-07 | 0 | 0 |
| W/S | 9623 |
Ig-82 |
34 | None | 0.9954 | None | 1.0 | None | 0.825 | 0.91 | 0.960224441878 | gnomAD-4.0.0 | 6.8417E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15939E-05 | 0 |
| W/R | 9731 |
Ig-83 |
34 | rs1226902114 |
0.9999 | -2.011 | 1.0 | None | 0.884 | 0.92 | 0.940290408551 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11309E-04 | None | 0 | None | 0 | 0 | 0 |
| W/R | 9731 |
Ig-83 |
34 | rs1226902114 |
0.9999 | -2.011 | 1.0 | None | 0.884 | 0.92 | 0.940290408551 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9253E-04 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 9731 |
Ig-83 |
34 | rs1226902114 |
0.9999 | -2.011 | 1.0 | None | 0.884 | 0.92 | 0.940290408551 | gnomAD-4.0.0 | 3.18342E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.8826E-05 | 0 | 2.85915E-06 | 0 | 0 |
| W/C | 9934 |
Ig-84 |
35 | rs1046404085 |
0.9991 | None | 1.0 | None | 0.879 | 0.927 | 0.72990446813 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 9934 |
Ig-84 |
35 | rs1046404085 |
0.9991 | None | 1.0 | None | 0.879 | 0.927 | 0.72990446813 | gnomAD-4.0.0 | 6.57376E-06 | None | None | None | None | N | None | 2.41394E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 9934 |
Ig-84 |
35 | rs753005176 |
0.9998 | -2.25 | 1.0 | None | 0.901 | 0.957 | 0.954018241302 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.05E-06 | 0 |
| W/R | 9934 |
Ig-84 |
35 | rs753005176 |
0.9998 | -2.25 | 1.0 | None | 0.901 | 0.957 | 0.954018241302 | gnomAD-4.0.0 | 4.11023E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.50088E-06 | 0 | 1.65843E-05 |
| W/R | 10021 |
Ig-85 |
33 | None | 0.9993 | None | 1.0 | None | 0.878 | 0.921 | 0.957306780153 | gnomAD-4.0.0 | 1.59086E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| W/R | 13906 |
Ig-89 |
31 | None | 0.9998 | None | 0.999 | D | 0.811 | 0.776 | 0.907460717844 | gnomAD-4.0.0 | 1.64324E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9494E-06 | 0 | 0 |
| W/C | 14351 |
Ig-94 |
33 | rs755308403 |
0.9986 | -1.233 | 0.027 | D | 0.609 | 0.711 | 0.599286835281 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| W/C | 14351 |
Ig-94 |
33 | rs755308403 |
0.9986 | -1.233 | 0.027 | D | 0.609 | 0.711 | 0.599286835281 | gnomAD-4.0.0 | 1.36907E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.32072E-05 | 0 |
| W/G | 14351 |
Ig-94 |
33 | rs794729430 |
0.982 | None | 0.964 | D | 0.729 | 0.696 | 0.813335362941 | gnomAD-4.0.0 | 1.59299E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86072E-06 | 0 | 0 |
| W/R | 14351 |
Ig-94 |
33 | rs794729430 |
0.9994 | -2.177 | 0.988 | D | 0.827 | 0.75 | 0.828620666864 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/R | 14351 |
Ig-94 |
33 | rs794729430 |
0.9994 | -2.177 | 0.988 | D | 0.827 | 0.75 | 0.828620666864 | gnomAD-4.0.0 | 1.59299E-06 | None | None | None | None | N | None | 0 | 2.28854E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 14351 |
Ig-94 |
33 | None | 0.9976 | None | 0.931 | D | 0.815 | 0.515 | 0.839276590097 | gnomAD-4.0.0 | 6.84543E-07 | None | None | None | None | N | None | 2.99204E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/L | 14618 |
Ig-97 |
33 | None | 0.9188 | None | 1.0 | D | 0.807 | 0.87 | 0.945421230048 | gnomAD-4.0.0 | 6.84456E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99609E-07 | 0 | 0 |
| W/R | 14618 |
Ig-97 |
33 | rs1307996353 |
0.9989 | None | 1.0 | D | 0.864 | 0.936 | 0.960038039894 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 14618 |
Ig-97 |
33 | rs1307996353 |
0.9989 | None | 1.0 | D | 0.864 | 0.936 | 0.960038039894 | gnomAD-4.0.0 | 6.5773E-06 | None | None | None | None | N | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 14974 |
Ig-101 |
33 | None | 0.9993 | None | 1.0 | D | 0.863 | 0.914 | 0.952822815892 | gnomAD-4.0.0 | 1.2011E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31336E-06 | 0 | 0 |
| W/R | 15063 |
Ig-102 |
33 | None | 0.9989 | None | 1.0 | D | 0.884 | 0.9 | 0.953210753606 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 15152 |
Ig-103 |
33 | rs745384075 |
0.9998 | -2.227 | 1.0 | D | 0.839 | 0.919 | 0.945276877397 | gnomAD-2.1.1 | 7.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| W/R | 15152 |
Ig-103 |
33 | rs745384075 |
0.9998 | -2.227 | 1.0 | D | 0.839 | 0.919 | 0.945276877397 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/R | 15152 |
Ig-103 |
33 | rs745384075 |
0.9998 | -2.227 | 1.0 | D | 0.839 | 0.919 | 0.945276877397 | gnomAD-4.0.0 | 1.11655E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.44179E-05 | 0 | 1.60369E-05 |
| W/C | 15423 |
Ig-106 |
33 | rs2058068284 |
0.9991 | None | 1.0 | D | 0.831 | 0.805 | 0.793074248023 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/R | 15512 |
Ig-107 |
33 | None | 0.9997 | None | 1.0 | D | 0.862 | 0.915 | 0.929210780582 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
| W/C | 15601 |
Ig-108 |
34 | None | 0.9934 | None | 1.0 | D | 0.817 | 0.839 | 0.658254632336 | gnomAD-4.0.0 | 1.59569E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8654E-06 | 0 | 0 |
| W/R | 15601 |
Ig-108 |
34 | None | 0.9986 | None | 1.0 | D | 0.889 | 0.882 | 0.928854916774 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/R | 15996 |
Ig-109 |
29 | rs1324349099 |
0.9985 | -1.894 | 0.983 | D | 0.872 | 0.907 | 0.929092460382 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| W/R | 15996 |
Ig-109 |
29 | rs1324349099 |
0.9985 | -1.894 | 0.983 | D | 0.872 | 0.907 | 0.929092460382 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/C | 16988 |
Ig-111 |
34 | rs1252820791 |
0.9923 | -1.893 | 1.0 | D | 0.782 | 0.908 | 0.921463888424 | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 0 | 1.70116E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 16988 |
Ig-111 |
34 | rs1252820791 |
0.9923 | -1.893 | 1.0 | D | 0.782 | 0.908 | 0.921463888424 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 16988 |
Ig-111 |
34 | rs1252820791 |
0.9923 | -1.893 | 1.0 | D | 0.782 | 0.908 | 0.921463888424 | gnomAD-4.0.0 | 6.41465E-06 | None | None | None | None | N | None | 0 | 8.48666E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 16988 |
Ig-111 |
34 | rs1473745606 |
0.9951 | -3.339 | 1.0 | D | 0.839 | 0.882 | 0.965446948986 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.64E-05 | 0 | 0 |
| W/S | 16988 |
Ig-111 |
34 | rs1473745606 |
0.9951 | -3.339 | 1.0 | D | 0.839 | 0.882 | 0.965446948986 | gnomAD-4.0.0 | 1.59337E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88324E-05 | 0 | 0 | 0 | 0 |
| W/G | 17281 |
Ig-112 |
31 | None | 0.9946 | None | 1.0 | D | 0.901 | 0.933 | 0.918551706158 | gnomAD-4.0.0 | 6.84709E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99913E-07 | 0 | 0 |
| W/R | 17281 |
Ig-112 |
31 | rs368846015 |
0.9997 | -1.912 | 1.0 | D | 0.946 | 0.945 | 0.944061380706 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 1.29433E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/R | 17281 |
Ig-112 |
31 | rs368846015 |
0.9997 | -1.912 | 1.0 | D | 0.946 | 0.945 | 0.944061380706 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20954E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 17281 |
Ig-112 |
31 | rs368846015 |
0.9997 | -1.912 | 1.0 | D | 0.946 | 0.945 | 0.944061380706 | gnomAD-4.0.0 | 6.82276E-06 | None | None | None | None | N | None | 9.36555E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 6.41293E-05 |
| W/C | 18000 |
Ig-114 |
33 | rs72646813 |
0.9989 | -1.622 | 1.0 | D | 0.831 | 0.915 | 0.671431388003 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 1.16387E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 18000 |
Ig-114 |
33 | rs72646813 |
0.9989 | -1.622 | 1.0 | D | 0.831 | 0.915 | 0.671431388003 | gnomAD-4.0.0 | 7.97107E-06 | None | None | None | None | N | None | 0 | 1.14542E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/G | 19126 |
Ig-117 |
32 | rs201912036 |
0.9907 | -3.524 | 1.0 | D | 0.82 | 0.938 | 0.902846591328 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| W/G | 19126 |
Ig-117 |
32 | rs201912036 |
0.9907 | -3.524 | 1.0 | D | 0.82 | 0.938 | 0.902846591328 | gnomAD-4.0.0 | 2.05315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69887E-06 | 0 | 0 |
| W/G | 19820 |
Ig-119 |
31 | None | 0.9955 | None | 1.0 | D | 0.82 | 0.907 | 0.736798250571 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| W/C | 20112 |
Ig-120 |
33 | None | 0.9984 | None | 1.0 | D | 0.791 | 0.819 | 0.872099035071 | gnomAD-4.0.0 | 6.84539E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99763E-07 | 0 | 0 |
| W/R | 20112 |
Ig-120 |
33 | rs547962583 |
0.9995 | -1.926 | 1.0 | D | 0.868 | 0.922 | 0.942845101236 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94326E-04 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 20112 |
Ig-120 |
33 | rs547962583 |
0.9995 | -1.926 | 1.0 | D | 0.868 | 0.922 | 0.942845101236 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| W/R | 20112 |
Ig-120 |
33 | rs547962583 |
0.9995 | -1.926 | 1.0 | D | 0.868 | 0.922 | 0.942845101236 | gnomAD-4.0.0 | 1.85989E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23115E-05 | None | 0 | 0 | 1.69583E-06 | 0 | 0 |
| W/R | 20510 |
Ig-121 |
32 | None | 0.9994 | None | 0.997 | D | 0.871 | 0.951 | 0.938358567851 | gnomAD-4.0.0 | 3.20497E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.74994E-06 | 0 | 0 |
| W/G | 20803 |
Ig-122 |
35 | None | 0.9947 | None | 1.0 | D | 0.791 | 0.895 | 0.893705206797 | gnomAD-4.0.0 | 6.84568E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9987E-07 | 0 | 0 |
| W/R | 20803 |
Ig-122 |
35 | rs376460156 |
0.9996 | -2.108 | 1.0 | D | 0.865 | 0.897 | 0.943242432309 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| W/R | 20803 |
Ig-122 |
35 | rs376460156 |
0.9996 | -2.108 | 1.0 | D | 0.865 | 0.897 | 0.943242432309 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| W/R | 20803 |
Ig-122 |
35 | rs376460156 |
0.9996 | -2.108 | 1.0 | D | 0.865 | 0.897 | 0.943242432309 | gnomAD-4.0.0 | 1.86004E-05 | None | None | None | None | N | None | 1.33536E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.37439E-05 | 0 | 1.60195E-05 |
| W/R | 21500 |
Ig-124 |
32 | rs2048669165 |
0.9996 | None | 1.0 | D | 0.891 | 0.93 | 0.936542578583 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07727E-04 | 0 |
| W/R | 21500 |
Ig-124 |
32 | rs2048669165 |
0.9996 | None | 1.0 | D | 0.891 | 0.93 | 0.936542578583 | gnomAD-4.0.0 | 6.58831E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07727E-04 | 0 |
| W/C | 22295 |
Ig-126 |
31 | rs1202934929 |
0.9985 | -1.682 | 1.0 | D | 0.751 | 0.913 | 0.920014922596 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/C | 22295 |
Ig-126 |
31 | rs1202934929 |
0.9985 | -1.682 | 1.0 | D | 0.751 | 0.913 | 0.920014922596 | gnomAD-4.0.0 | 2.56498E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.79058E-06 | 0 | 0 |
| W/C | 22584 |
Ig-127 |
25 | rs750330303 |
0.9973 | -1.879 | 1.0 | D | 0.797 | 0.891 | 0.920170856376 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| W/C | 22584 |
Ig-127 |
25 | rs750330303 |
0.9973 | -1.879 | 1.0 | D | 0.797 | 0.891 | 0.920170856376 | gnomAD-4.0.0 | 2.05326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69892E-06 | 0 | 0 |
| W/G | 22584 |
Ig-127 |
25 | rs762387858 |
0.9902 | -2.86 | 1.0 | D | 0.815 | 0.946 | 0.92633486712 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| W/G | 22584 |
Ig-127 |
25 | rs762387858 |
0.9902 | -2.86 | 1.0 | D | 0.815 | 0.946 | 0.92633486712 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| W/G | 22584 |
Ig-127 |
25 | rs762387858 |
0.9902 | -2.86 | 1.0 | D | 0.815 | 0.946 | 0.92633486712 | gnomAD-4.0.0 | 5.57914E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.63017E-06 | 0 | 0 |
| W/R | 23378 |
Ig-129 |
34 | rs1709952392 |
0.9996 | None | 1.0 | D | 0.873 | 0.926 | 0.93566570447 | gnomAD-4.0.0 | 6.84881E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00354E-07 | 0 | 0 |
| W/S | 23378 |
Ig-129 |
34 | rs1172742481 |
0.9975 | -3.417 | 1.0 | D | 0.859 | 0.91 | 0.960894019804 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.96E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/S | 23378 |
Ig-129 |
34 | rs1172742481 |
0.9975 | -3.417 | 1.0 | D | 0.859 | 0.91 | 0.960894019804 | gnomAD-4.0.0 | 1.59514E-06 | None | None | None | None | N | None | 0 | 0 | None | 4.7719E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 24063 |
Ig-131 |
35 | rs1377985355 |
0.9993 | None | 1.0 | D | 0.897 | 0.94 | 0.947933090619 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/R | 24063 |
Ig-131 |
35 | rs1377985355 |
0.9993 | None | 1.0 | D | 0.897 | 0.94 | 0.947933090619 | gnomAD-4.0.0 | 2.47952E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39108E-06 | 0 | 0 |
| W/R | 25831 |
Ig-136 |
34 | None | 0.9992 | None | 1.0 | D | 0.889 | 0.943 | 0.94782245772 | gnomAD-4.0.0 | 9.6026E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.05E-05 | 0 | 0 |
| W/L | 26227 |
Ig-137 |
35 | rs1706315809 |
0.9576 | None | 1.0 | D | 0.789 | 0.923 | 0.951195235736 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/L | 26227 |
Ig-137 |
35 | rs1706315809 |
0.9576 | None | 1.0 | D | 0.789 | 0.923 | 0.951195235736 | gnomAD-4.0.0 | 1.31539E-05 | None | None | None | None | N | None | 4.82835E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 26626 |
Ig-138 |
33 | None | 0.9996 | None | 1.0 | D | 0.868 | 0.917 | 0.94079955673 | gnomAD-4.0.0 | 3.18289E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.53562E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 26913 |
Ig-139 |
34 | rs1705368893 |
0.9931 | None | 0.967 | D | 0.841 | 0.834 | 0.95226174331 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 26913 |
Ig-139 |
34 | rs1705368893 |
0.9931 | None | 0.967 | D | 0.841 | 0.834 | 0.95226174331 | gnomAD-4.0.0 | 6.57601E-06 | None | None | None | None | N | None | 2.41406E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 27709 |
Ig-141 |
34 | None | 0.9995 | None | 1.0 | D | 0.828 | 0.847 | 0.762902998451 | gnomAD-4.0.0 | 1.59151E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| W/G | 29873 |
Ig-147 |
32 | None | 0.9901 | None | 1.0 | D | 0.822 | 0.913 | 0.932922261461 | gnomAD-4.0.0 | 2.05765E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69837E-06 | 0 | 0 |
| W/R | 29873 |
Ig-147 |
32 | None | 0.9992 | None | 1.0 | D | 0.879 | 0.906 | 0.948843343272 | gnomAD-4.0.0 | 1.37177E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.0388E-05 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 30165 |
Ig-148 |
34 | rs761010373 |
0.9792 | -0.736 | 1.0 | D | 0.827 | 0.863 | 0.867892837264 | gnomAD-2.1.1 | 4.24E-06 | None | None | None | None | N | None | 6.51E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| W/C | 30165 |
Ig-148 |
34 | rs761010373 |
0.9792 | -0.736 | 1.0 | D | 0.827 | 0.863 | 0.867892837264 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/C | 30165 |
Ig-148 |
34 | rs761010373 |
0.9792 | -0.736 | 1.0 | D | 0.827 | 0.863 | 0.867892837264 | gnomAD-4.0.0 | 6.57151E-06 | None | None | None | None | N | None | 2.41301E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 30165 |
Ig-148 |
34 | None | 0.9886 | None | 1.0 | D | 0.87 | 0.827 | 0.951261571319 | gnomAD-4.0.0 | 2.08219E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.81932E-06 | 0 | 1.68413E-05 |
| W/C | 30560 |
Ig-149 |
29 | None | 0.9905 | None | 1.0 | D | 0.763 | 0.867 | 0.908265275133 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/C | 31249 |
Ig-151 |
32 | None | 0.9933 | None | 1.0 | D | 0.8 | 0.879 | 0.723653669168 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/L | 31249 |
Ig-151 |
32 | None | 0.8897 | None | 1.0 | D | 0.818 | 0.843 | 0.905828360724 | gnomAD-4.0.0 | 6.84186E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99434E-07 | 0 | 0 |
| W/R | 31249 |
Ig-151 |
32 | None | 0.9983 | None | 1.0 | D | 0.865 | 0.94 | 0.946935086327 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/C | 31649 |
Ig-152 |
29 | None | 0.999 | None | 1.0 | D | 0.813 | 0.893 | 0.766217489468 | gnomAD-4.0.0 | 6.84214E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9948E-07 | 0 | 0 |
| W/R | 31649 |
Ig-152 |
29 | rs1697138621 |
0.9997 | None | 1.0 | D | 0.873 | 0.91 | 0.951794544108 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/R | 31649 |
Ig-152 |
29 | rs1697138621 |
0.9997 | None | 1.0 | D | 0.873 | 0.91 | 0.951794544108 | gnomAD-4.0.0 | 6.57341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47029E-05 | 0 | 0 |
| W/C | 32048 |
Ig-153 |
32 | None | 0.9976 | None | 1.0 | D | 0.813 | 0.916 | 0.81521232876 | gnomAD-4.0.0 | 1.59151E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85876E-06 | 0 | 0 |
| W/C | 32738 |
Ig-155 |
31 | rs764039252 |
0.999 | -2.227 | 1.0 | D | 0.807 | 0.696 | 0.887305418718 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| W/R | 32738 |
Ig-155 |
31 | None | 0.9996 | None | 1.0 | D | 0.873 | 0.92 | 0.930611013341 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/C | 33134 |
Ig-156 |
34 | rs1222519078 |
0.9987 | -1.621 | 1.0 | D | 0.753 | 0.797 | 0.797336444703 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| W/C | 33134 |
Ig-156 |
34 | rs1222519078 |
0.9987 | -1.621 | 1.0 | D | 0.753 | 0.797 | 0.797336444703 | gnomAD-4.0.0 | 6.84244E-07 | None | None | None | None | N | None | 0 | 2.23694E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 33134 |
Ig-156 |
34 | None | 0.9998 | None | 1.0 | D | 0.848 | 0.889 | 0.958484061125 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| W/S | 33134 |
Ig-156 |
34 | None | 0.9984 | None | 1.0 | D | 0.827 | 0.788 | 0.93578121469 | gnomAD-4.0.0 | 1.59151E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85855E-06 | 0 | 0 |
| W/R | 33529 |
Ig-158 |
34 | rs998397847 |
0.9999 | None | 1.0 | D | 0.859 | 0.919 | 0.942631964305 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 33529 |
Ig-158 |
34 | rs998397847 |
0.9999 | None | 1.0 | D | 0.859 | 0.919 | 0.942631964305 | gnomAD-4.0.0 | 3.71858E-06 | None | None | None | None | N | None | 2.67008E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39066E-06 | 0 | 0 |
| W/S | 33529 |
Ig-158 |
34 | rs1222059449 |
0.9989 | None | 1.0 | D | 0.837 | 0.881 | 0.958753196929 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/S | 33529 |
Ig-158 |
34 | rs1222059449 |
0.9989 | None | 1.0 | D | 0.837 | 0.881 | 0.958753196929 | gnomAD-4.0.0 | 6.57471E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47029E-05 | 0 | 0 |
| W/C | 34170 |
Ig-160 |
34 | rs1559033550 |
0.9962 | None | 1.0 | D | 0.813 | 0.867 | 0.755046456886 | gnomAD-4.0.0 | 3.18193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 6.04705E-05 |
| W/G | 34170 |
Ig-160 |
34 | rs778786999 |
0.9864 | None | 1.0 | D | 0.822 | 0.9 | 0.777323892525 | gnomAD-4.0.0 | 6.84157E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99413E-07 | 0 | 0 |
| W/R | 34170 |
Ig-160 |
34 | rs778786999 |
0.9993 | -2.075 | 1.0 | D | 0.867 | 0.88 | 0.951172234049 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| W/R | 34170 |
Ig-160 |
34 | rs778786999 |
0.9993 | -2.075 | 1.0 | D | 0.867 | 0.88 | 0.951172234049 | gnomAD-4.0.0 | 6.84157E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99413E-07 | 0 | 0 |
| W/C | 34291 |
Ig-161 |
34 | None | 0.9968 | None | 0.999 | D | 0.853 | 0.907 | 0.786693768516 | gnomAD-4.0.0 | 1.59102E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77254E-05 | None | 0 | 0 | 0 | 0 | 0 |
| W/G | 34291 |
Ig-161 |
34 | rs1690204801 |
0.9917 | None | 0.997 | D | 0.842 | 0.922 | 0.834446456457 | gnomAD-4.0.0 | 3.18196E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.54508E-05 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 34396 |
Ig-162 |
34 | rs1575264600 |
0.9998 | None | 1.0 | D | 0.86 | 0.93 | 0.92887255943 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/R | 34396 |
Ig-162 |
34 | rs1575264600 |
0.9998 | None | 1.0 | D | 0.86 | 0.93 | 0.92887255943 | gnomAD-4.0.0 | 2.47874E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39028E-06 | 0 | 0 |
| W/L | 34975 |
Ig-163 |
34 | None | 0.9173 | None | 0.885 | D | 0.797 | 0.869 | 0.947801904728 | gnomAD-4.0.0 | 6.84141E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.994E-07 | 0 | 0 |
| W/R | 34975 |
Ig-163 |
34 | None | 0.9995 | None | 0.997 | D | 0.862 | 0.925 | 0.932282890813 | gnomAD-4.0.0 | 1.59089E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85757E-06 | 0 | 0 |
| W/S | 34975 |
Ig-163 |
34 | rs1181086213 |
0.9959 | None | 0.982 | D | 0.86 | 0.914 | 0.959178105942 | gnomAD-4.0.0 | 1.36828E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7988E-06 | 0 | 0 |
| W/R | 35162 |
Ig-164 |
34 | None | 0.9979 | None | 0.999 | D | 0.824 | 0.936 | 0.943761194631 | gnomAD-4.0.0 | 3.18174E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71504E-06 | 0 | 0 |
| W/S | 35162 |
Ig-164 |
34 | rs886042795 |
0.9874 | -2.592 | 0.999 | D | 0.8 | 0.895 | 0.964451493746 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| W/S | 35162 |
Ig-164 |
34 | rs886042795 |
0.9874 | -2.592 | 0.999 | D | 0.8 | 0.895 | 0.964451493746 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| W/S | 35162 |
Ig-164 |
34 | rs886042795 |
0.9874 | -2.592 | 0.999 | D | 0.8 | 0.895 | 0.964451493746 | gnomAD-4.0.0 | 6.57307E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47007E-05 | 0 | 0 |
| W/C | 35453 |
Ig-166 |
34 | None | 0.9891 | None | 1.0 | D | 0.808 | 0.883 | 0.773222466804 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
| W/R | 35453 |
Ig-166 |
34 | None | 0.9974 | None | 0.999 | D | 0.832 | 0.92 | 0.951627751765 | gnomAD-4.0.0 | 1.61741E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.90436E-06 | 0 | 0 |
| W/C | 35638 |
Ig-167 |
32 | rs758497512 |
0.9975 | -1.192 | 0.999 | D | 0.849 | 0.78 | 0.912328163995 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| W/C | 35638 |
Ig-167 |
32 | rs758497512 |
0.9975 | -1.192 | 0.999 | D | 0.849 | 0.78 | 0.912328163995 | gnomAD-4.0.0 | 6.84157E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| W/R | 35638 |
Ig-167 |
32 | rs1408667252 |
0.9992 | None | 0.991 | D | 0.875 | 0.828 | 0.914245553373 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/R | 35638 |
Ig-167 |
32 | rs1408667252 |
0.9992 | None | 0.991 | D | 0.875 | 0.828 | 0.914245553373 | gnomAD-4.0.0 | 6.84151E-07 | None | None | None | None | N | None | 2.98704E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| W/S | 35735 |
Ig-168 |
34 | None | 0.9873 | None | 1.0 | D | 0.83 | 0.893 | 0.962606100052 | gnomAD-4.0.0 | 6.86826E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02253E-07 | 0 | 0 |
| W/R | 35930 |
Ig-169 |
34 | rs1018591024 |
0.9987 | -2.172 | 1.0 | D | 0.836 | 0.938 | 0.942593547874 |
Zheng (2016)
| None |
LGMD2J
|
hom | None | -0.843(OBSL1) -1.308(OBSCN) | N | WES prioritisation of single 5-generation CN family; co-segregation within family (recessive inheritance, n = 3, 3 affected, (6 total)) | None | None | None | None | None | None | None | None | None | None | None |
| W/R | 35930 |
Ig-169 |
34 | rs1018591024 |
0.9987 | -2.172 | 1.0 | D | 0.836 | 0.938 | 0.942593547874 | gnomAD-4.0.0 | 2.7366E-06 | None | None | None | -0.843(OBSL1) -1.308(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59762E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.