Structural position:
- Domain Type: Ig
- Aligned Position: 56
- Secondary Structure Element: e
- Secondary Structure Region: β-strand C'
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V/L | 45 |
Ig-1 |
40 | rs142028110 |
0.1763 | -0.047 | 0.002 | N | 0.529 | 0.202 | 0.417460480802 | gnomAD-2.1.1 | 2.83E-05 | None | None | None | -0.635(TCAP) | N | None | 2.80336E-04 | 2.82E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 45 |
Ig-1 |
40 | rs142028110 |
0.1763 | -0.047 | 0.002 | N | 0.529 | 0.202 | 0.417460480802 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | -0.635(TCAP) | N | None | 1.68952E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 45 |
Ig-1 |
40 | rs142028110 |
0.1763 | -0.047 | 0.002 | N | 0.529 | 0.202 | 0.417460480802 | gnomAD-4.0.0 | 6.84074E-07 | None | None | None | -0.635(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99295E-07 | 0 | 0 |
| V/M | 45 |
Ig-1 |
40 | None | 0.1428 | None | 0.404 | N | 0.544 | 0.197 | 0.517377062552 | gnomAD-4.0.0 | 6.84074E-07 | None | None | None | -0.362(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99295E-07 | 0 | 0 |
| E/K | 143 |
Ig-2 |
40 | rs754182768 |
0.7798 | -0.033 | 0.998 | N | 0.528 | 0.444 | 0.433600339574 | gnomAD-2.1.1 | 3.58E-05 | None | None | None | -0.6(TCAP) | N | None | 0 | 8.67E-05 | None | 0 | 5.44E-05 | None | 0 | None | 0 | 4.4E-05 | 0 |
| E/K | 143 |
Ig-2 |
40 | rs754182768 |
0.7798 | -0.033 | 0.998 | N | 0.528 | 0.444 | 0.433600339574 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | -0.6(TCAP) | N | None | 2.41E-05 | 6.55E-05 | 0 | 0 | 1.92382E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 143 |
Ig-2 |
40 | rs754182768 |
0.7798 | -0.033 | 0.998 | N | 0.528 | 0.444 | 0.433600339574 | gnomAD-4.0.0 | 3.71746E-05 | None | None | None | -0.6(TCAP) | N | None | 6.67414E-05 | 6.66667E-05 | None | 0 | 4.45534E-05 | None | 0 | 0 | 3.72877E-05 | 3.29388E-05 | 3.20092E-05 |
| E/V | 143 |
Ig-2 |
40 | None | 0.6641 | None | 0.996 | N | 0.708 | 0.577 | 0.697057897476 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | -0.31(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| R/C | 1330 |
Ig-5 |
40 | rs771294359 |
0.7973 | -0.235 | 1.0 | N | 0.753 | 0.536 | 0.729979875932 | gnomAD-2.1.1 | 1.32039E-04 | None | None | None | None | N | None | 0 | 5.79744E-04 | None | 0 | 0 | None | 2.28878E-04 | None | 0 | 2.66E-05 | 4.93097E-04 |
| R/C | 1330 |
Ig-5 |
40 | rs771294359 |
0.7973 | -0.235 | 1.0 | N | 0.753 | 0.536 | 0.729979875932 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/C | 1330 |
Ig-5 |
40 | rs771294359 |
0.7973 | -0.235 | 1.0 | N | 0.753 | 0.536 | 0.729979875932 | gnomAD-4.0.0 | 4.21362E-05 | None | None | None | None | N | None | 2.6656E-05 | 4.00187E-04 | None | 0 | 4.46209E-05 | None | 0 | 0 | 2.11874E-05 | 1.31761E-04 | 4.80046E-05 |
| R/H | 1330 |
Ig-5 |
40 | rs761402128 |
0.6173 | -0.757 | 1.0 | N | 0.769 | 0.385 | None | gnomAD-2.1.1 | 4.4E-05 | None | None | None | None | N | None | 6.16E-05 | 8.7E-05 | None | 0 | 0 | None | 0 | None | 0 | 5.33E-05 | 1.6442E-04 |
| R/H | 1330 |
Ig-5 |
40 | rs761402128 |
0.6173 | -0.757 | 1.0 | N | 0.769 | 0.385 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/H | 1330 |
Ig-5 |
40 | rs761402128 |
0.6173 | -0.757 | 1.0 | N | 0.769 | 0.385 | None | gnomAD-4.0.0 | 4.09007E-05 | None | None | None | None | N | None | 5.33988E-05 | 6.67156E-05 | None | 0 | 8.92339E-05 | None | 0 | 0 | 4.06802E-05 | 4.3929E-05 | 3.20164E-05 |
| R/L | 1330 |
Ig-5 |
40 | None | 0.7789 | None | 1.0 | N | 0.635 | 0.504 | 0.630199317251 | gnomAD-4.0.0 | 6.84231E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15972E-05 | 0 |
| Q/H | 1496 |
Ig-6 |
40 | rs1451784393 |
0.6565 | -0.135 | 0.999 | N | 0.597 | 0.287 | 0.397540356873 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.63E-05 | 0 | 0 |
| Q/H | 1496 |
Ig-6 |
40 | rs1451784393 |
0.6565 | -0.135 | 0.999 | N | 0.597 | 0.287 | 0.397540356873 | gnomAD-4.0.0 | 1.59107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.8831E-05 | 0 | 0 | 0 | 0 |
| I/S | 1595 |
Ig-7 |
40 | rs1012905833 |
0.9762 | -0.631 | 1.0 | N | 0.715 | 0.562 | 0.808767119372 | gnomAD-2.1.1 | 1.06E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.33E-05 | 0 |
| I/S | 1595 |
Ig-7 |
40 | rs1012905833 |
0.9762 | -0.631 | 1.0 | N | 0.715 | 0.562 | 0.808767119372 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| I/S | 1595 |
Ig-7 |
40 | rs1012905833 |
0.9762 | -0.631 | 1.0 | N | 0.715 | 0.562 | 0.808767119372 | gnomAD-4.0.0 | 1.30114E-05 | None | None | None | None | N | None | 1.33494E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69492E-05 | 0 | 0 |
| I/V | 1595 |
Ig-7 |
40 | None | 0.356 | None | 0.993 | N | 0.305 | 0.265 | 0.678929657206 | gnomAD-4.0.0 | 1.59064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85677E-06 | 0 | 0 |
| P/L | 1744 |
Ig-8 |
42 | rs75686037 |
0.2692 | 0.045 | 1.0 | D | 0.732 | 0.554 | None | gnomAD-2.1.1 | 6.73712E-03 | None | None | None | None | N | None | 2.00321E-04 | 3.58132E-02 | None | 5.79598E-04 | 2.68055E-02 | None | 7.18719E-04 | None | 1.5935E-04 | 2.79759E-04 | 3.88889E-03 |
| P/L | 1744 |
Ig-8 |
42 | rs75686037 |
0.2692 | 0.045 | 1.0 | D | 0.732 | 0.554 | None | gnomAD-3.1.2 | 2.37911E-03 | None | None | None | None | N | None | 2.41429E-04 | 1.21728E-02 | 0 | 1.15274E-03 | 2.6772E-02 | None | 2.82486E-04 | 0 | 1.46998E-04 | 8.28157E-04 | 2.87081E-03 |
| P/L | 1744 |
Ig-8 |
42 | rs75686037 |
0.2692 | 0.045 | 1.0 | D | 0.732 | 0.554 | None | 1000 genomes | 6.98882E-03 | None | None | None | None | N | None | 8E-04 | 2.45E-02 | None | None | 1.69E-02 | 0 | None | None | None | 0 | None |
| P/L | 1744 |
Ig-8 |
42 | rs75686037 |
0.2692 | 0.045 | 1.0 | D | 0.732 | 0.554 | None | gnomAD-4.0.0 | 1.99004E-03 | None | None | None | None | N | None | 3.06601E-04 | 2.80167E-02 | None | 8.10701E-04 | 2.33709E-02 | None | 1.87465E-04 | 4.94886E-04 | 1.91525E-04 | 8.34395E-04 | 1.90388E-03 |
| P/S | 1744 |
Ig-8 |
42 | rs761807419 |
0.3312 | -0.337 | 1.0 | D | 0.735 | 0.605 | 0.42805410278 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| P/S | 1744 |
Ig-8 |
42 | rs761807419 |
0.3312 | -0.337 | 1.0 | D | 0.735 | 0.605 | 0.42805410278 | gnomAD-4.0.0 | 1.2314E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.5288E-05 | 0 | 1.65585E-05 |
| L/F | 1880 |
Ig-9 |
40 | rs2092208587 |
0.6228 | None | 1.0 | D | 0.674 | 0.424 | 0.66962095848 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 2213 |
Ig-11 |
40 | rs745719077 |
0.1973 | -0.562 | 0.999 | D | 0.501 | 0.236 | 0.268660756437 | gnomAD-2.1.1 | 1.42E-05 | None | None | None | None | N | None | 4.01E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.33E-05 | 0 |
| E/D | 2213 |
Ig-11 |
40 | rs745719077 |
0.1973 | -0.562 | 0.999 | D | 0.501 | 0.236 | 0.268660756437 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| E/D | 2213 |
Ig-11 |
40 | rs745719077 |
0.1973 | -0.562 | 0.999 | D | 0.501 | 0.236 | 0.268660756437 | gnomAD-4.0.0 | 1.85881E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69494E-06 | 0 | 1.60041E-05 |
| E/D | 2305 |
Ig-12 |
39 | rs778211562 |
0.4184 | None | 0.999 | D | 0.479 | 0.33 | 0.337621943819 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/D | 2305 |
Ig-12 |
39 | rs778211562 |
0.4184 | None | 0.999 | D | 0.479 | 0.33 | 0.337621943819 | gnomAD-4.0.0 | 6.57108E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46972E-05 | 0 | 0 |
| E/G | 2305 |
Ig-12 |
39 | None | 0.4051 | None | 1.0 | D | 0.701 | 0.549 | 0.653189724925 | gnomAD-4.0.0 | 1.59062E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| E/K | 2305 |
Ig-12 |
39 | rs367761468 |
0.2785 | -0.223 | 0.999 | N | 0.606 | 0.33 | None | gnomAD-2.1.1 | 3.98E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.82E-05 | 0 |
| E/K | 2305 |
Ig-12 |
39 | rs367761468 |
0.2785 | -0.223 | 0.999 | N | 0.606 | 0.33 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 4.78469E-04 |
| E/K | 2305 |
Ig-12 |
39 | rs367761468 |
0.2785 | -0.223 | 0.999 | N | 0.606 | 0.33 | None | gnomAD-4.0.0 | 7.68294E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.03392E-04 | 0 | 3.20082E-05 |
| E/Q | 2305 |
Ig-12 |
39 | rs367761468 |
0.1942 | -0.761 | 1.0 | D | 0.605 | 0.256 | None | gnomAD-2.1.1 | 1.2E-05 | None | None | None | None | N | None | 1.8457E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 2305 |
Ig-12 |
39 | rs367761468 |
0.1942 | -0.761 | 1.0 | D | 0.605 | 0.256 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/Q | 2305 |
Ig-12 |
39 | rs367761468 |
0.1942 | -0.761 | 1.0 | D | 0.605 | 0.256 | None | gnomAD-4.0.0 | 1.11527E-05 | None | None | None | None | N | None | 8.01004E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01697E-05 | 0 | 0 |
| E/Q | 2394 |
Ig-13 |
39 | rs537269762 |
0.1159 | 0.171 | 0.986 | D | 0.447 | 0.268 | 0.355242300401 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 2394 |
Ig-13 |
39 | rs537269762 |
0.1159 | 0.171 | 0.986 | D | 0.447 | 0.268 | 0.355242300401 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 0 | 4.58355E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 2394 |
Ig-13 |
39 | rs537269762 |
0.1159 | 0.171 | 0.986 | D | 0.447 | 0.268 | 0.355242300401 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/Q | 2394 |
Ig-13 |
39 | rs537269762 |
0.1159 | 0.171 | 0.986 | D | 0.447 | 0.268 | 0.355242300401 | gnomAD-4.0.0 | 1.53653E-05 | None | None | None | None | N | None | 0 | 1.86377E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84026E-05 |
| E/V | 2394 |
Ig-13 |
39 | rs929251010 |
0.0954 | None | 0.92 | N | 0.389 | 0.307 | 0.642492775995 | gnomAD-4.0.0 | 1.59055E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8566E-06 | 0 | 0 |
| E/K | 2571 |
Ig-15 |
39 | rs149660690 |
0.1566 | -0.117 | 0.029 | N | 0.314 | 0.203 | None | gnomAD-2.1.1 | 5.68E-05 | None | None | None | None | N | None | 6.06208E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.77E-06 | 0 |
| E/K | 2571 |
Ig-15 |
39 | rs149660690 |
0.1566 | -0.117 | 0.029 | N | 0.314 | 0.203 | None | gnomAD-3.1.2 | 1.6442E-04 | None | None | None | None | N | None | 5.5577E-04 | 1.31027E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 2571 |
Ig-15 |
39 | rs149660690 |
0.1566 | -0.117 | 0.029 | N | 0.314 | 0.203 | None | 1000 genomes | 1.19808E-03 | None | None | None | None | N | None | 4.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/K | 2571 |
Ig-15 |
39 | rs149660690 |
0.1566 | -0.117 | 0.029 | N | 0.314 | 0.203 | None | gnomAD-4.0.0 | 3.34608E-05 | None | None | None | None | N | None | 5.33476E-04 | 3.33489E-05 | None | 0 | 0 | None | 0 | 0 | 4.23752E-06 | 0 | 1.12011E-04 |
| E/V | 2571 |
Ig-15 |
39 | None | 0.1453 | None | 0.029 | N | 0.39 | 0.24 | 0.484037581386 | gnomAD-4.0.0 | 1.59096E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77778E-05 | None | 0 | 0 | 0 | 0 | 0 |
| H/L | 2658 |
Ig-16 |
38 | None | 0.0648 | None | 0.014 | N | 0.341 | 0.234 | 0.325533332567 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| H/Q | 2658 |
Ig-16 |
38 | rs1158775069 |
0.0833 | None | 0.001 | N | 0.131 | 0.058 | 0.0986583533028 | gnomAD-4.0.0 | 1.59059E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85659E-06 | 0 | 0 |
| H/Y | 2658 |
Ig-16 |
38 | rs1023349406 |
0.0837 | None | 0.065 | N | 0.306 | 0.172 | 0.284150004643 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| V/L | 2746 |
Ig-17 |
40 | rs1056269539 |
0.0998 | None | None | N | 0.148 | 0.087 | 0.450152462452 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 2746 |
Ig-17 |
40 | rs1056269539 |
0.0998 | None | None | N | 0.148 | 0.087 | 0.450152462452 | gnomAD-4.0.0 | 6.57108E-06 | None | None | None | None | N | None | 2.41313E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 2833 |
Ig-18 |
39 | None | 0.5157 | None | 0.999 | D | 0.585 | 0.582 | 0.722574115261 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/G | 2920 |
Ig-19 |
39 | None | 0.7919 | None | 1.0 | D | 0.673 | 0.614 | 0.634766356543 | gnomAD-4.0.0 | 1.59046E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85651E-06 | 0 | 0 |
| E/Q | 2920 |
Ig-19 |
39 | rs911601060 |
0.5572 | -0.075 | 1.0 | D | 0.605 | 0.37 | 0.362960570912 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.44E-05 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 2920 |
Ig-19 |
39 | rs911601060 |
0.5572 | -0.075 | 1.0 | D | 0.605 | 0.37 | 0.362960570912 | gnomAD-4.0.0 | 1.59047E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77254E-05 | None | 0 | 0 | 0 | 0 | 0 |
| E/A | 3096 |
Ig-21 |
39 | None | 0.3295 | None | 0.822 | N | 0.548 | 0.508 | 0.489938136499 | gnomAD-4.0.0 | 1.36815E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79859E-06 | 0 | 0 |
| E/D | 3096 |
Ig-21 |
39 | None | 0.3797 | None | 0.822 | N | 0.516 | 0.131 | 0.262662153117 | gnomAD-4.0.0 | 1.59054E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0217E-05 |
| E/V | 3096 |
Ig-21 |
39 | rs772499668 |
0.3245 | 0.095 | 0.942 | D | 0.55 | 0.497 | 0.621312436561 | gnomAD-2.1.1 | 7.96E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 0 | 0 |
| E/V | 3096 |
Ig-21 |
39 | rs772499668 |
0.3245 | 0.095 | 0.942 | D | 0.55 | 0.497 | 0.621312436561 | gnomAD-4.0.0 | 4.78853E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.95588E-05 | 1.65579E-05 |
| E/K | 3185 |
Ig-22 |
39 | None | 0.4347 | None | 0.992 | D | 0.575 | 0.461 | 0.442567846599 | gnomAD-4.0.0 | 1.5906E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77439E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 3977 |
Ig-28 |
40 | None | 0.1145 | None | 0.001 | N | 0.153 | 0.102 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/Q | 4643 |
Ig-29 |
38 | None | 0.0942 | None | 1.0 | N | 0.732 | 0.181 | None | gnomAD-4.0.0 | 1.59208E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85958E-06 | 0 | 0 |
| A/S | 4834 |
Ig-31 |
40 | rs746792103 |
0.0889 | -0.113 | 0.565 | N | 0.477 | 0.077 | 0.17948927462 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| A/S | 4834 |
Ig-31 |
40 | rs746792103 |
0.0889 | -0.113 | 0.565 | N | 0.477 | 0.077 | 0.17948927462 | gnomAD-4.0.0 | 1.36839E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52029E-05 | None | 0 | 0 | 8.9946E-07 | 0 | 0 |
| A/T | 4834 |
Ig-31 |
40 | None | 0.0805 | None | 0.008 | N | 0.211 | 0.063 | 0.15556083564 | gnomAD-4.0.0 | 6.84197E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| K/N | 4927 |
Ig-32 |
40 | rs780599464 |
0.2394 | 0.2 | 0.007 | N | 0.291 | 0.129 | 0.126345400529 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| K/N | 4927 |
Ig-32 |
40 | rs780599464 |
0.2394 | 0.2 | 0.007 | N | 0.291 | 0.129 | 0.126345400529 | gnomAD-4.0.0 | 6.84233E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52156E-05 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 5021 |
Ig-33 |
41 | rs727503651 |
0.3069 | -0.577 | 0.801 | N | 0.387 | 0.113 | 0.314417295294 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 0 | 2.03169E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/D | 5021 |
Ig-33 |
41 | rs727503651 |
0.3069 | -0.577 | 0.801 | N | 0.387 | 0.113 | 0.314417295294 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 5021 |
Ig-33 |
41 | rs727503651 |
0.3069 | -0.577 | 0.801 | N | 0.387 | 0.113 | 0.314417295294 | gnomAD-4.0.0 | 1.40938E-05 | None | None | None | None | N | None | 1.69113E-05 | 1.52604E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84527E-05 |
| E/K | 5021 |
Ig-33 |
41 | rs779917005 |
0.1959 | 0.218 | 0.012 | N | 0.244 | 0.198 | 0.346315397577 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| Q/P | 5114 |
Ig-34 |
40 | None | 0.0876 | None | 0.007 | N | 0.167 | 0.248 | 0.176091768786 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 5207 |
Ig-35 |
40 | None | 0.1097 | None | None | N | 0.097 | 0.116 | 0.248417906384 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| P/H | 5300 |
Ig-36 |
40 | rs1248409979 |
0.2178 | None | 1.0 | N | 0.549 | 0.429 | 0.598413393357 | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| P/S | 5300 |
Ig-36 |
40 | rs1436998315 |
0.1591 | -0.65 | 0.925 | N | 0.376 | 0.274 | 0.306053231325 | gnomAD-4.0.0 | 6.8421E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65662E-05 |
| P/T | 5300 |
Ig-36 |
40 | None | 0.1279 | None | 0.961 | N | 0.403 | 0.288 | 0.483082108137 | gnomAD-4.0.0 | 1.36842E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79896E-06 | 0 | 0 |
| E/K | 5396 |
Ig-37 |
40 | rs780211454 |
0.1928 | 0.582 | 0.978 | N | 0.535 | 0.341 | 0.338110398507 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| E/K | 5396 |
Ig-37 |
40 | rs780211454 |
0.1928 | 0.582 | 0.978 | N | 0.535 | 0.341 | 0.338110398507 | gnomAD-4.0.0 | 1.59178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43283E-05 | 0 |
| E/D | 5489 |
Ig-38 |
40 | None | 0.3515 | None | 0.977 | D | 0.475 | 0.269 | 0.267755039894 | gnomAD-4.0.0 | 6.84254E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99496E-07 | 0 | 0 |
| E/K | 5489 |
Ig-38 |
40 | rs1171851091 |
0.3366 | 0.46 | 0.117 | N | 0.334 | 0.232 | 0.357929162469 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| E/K | 5583 |
Ig-39 |
41 | None | 0.1491 | None | 0.999 | N | 0.633 | 0.333 | 0.564798353577 | gnomAD-4.0.0 | 1.59117E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85811E-06 | 0 | 0 |
| I/N | 5676 |
Ig-40 |
40 | None | 0.0981 | None | 0.014 | N | 0.442 | 0.087 | 0.223847106136 | gnomAD-4.0.0 | 1.59132E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85853E-06 | 0 | 0 |
| E/A | 5769 |
Ig-41 |
40 | rs756902467 |
0.142 | -0.167 | 0.625 | D | 0.347 | 0.279 | 0.430010490656 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/A | 5769 |
Ig-41 |
40 | rs756902467 |
0.142 | -0.167 | 0.625 | D | 0.347 | 0.279 | 0.430010490656 | gnomAD-4.0.0 | 6.8423E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| E/G | 5769 |
Ig-41 |
40 | None | 0.178 | None | 0.801 | N | 0.373 | 0.436 | 0.534093007224 | gnomAD-4.0.0 | 6.8423E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99467E-07 | 0 | 0 |
| E/K | 5769 |
Ig-41 |
40 | None | 0.1195 | None | 0.051 | N | 0.237 | 0.188 | 0.311079019809 | gnomAD-4.0.0 | 1.36845E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79893E-06 | 0 | 0 |
| E/K | 5862 |
Ig-42 |
40 | rs756303980 |
0.1496 | 0.271 | 0.999 | D | 0.646 | 0.439 | 0.541105671861 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.86E-06 | 0 |
| E/K | 5862 |
Ig-42 |
40 | rs756303980 |
0.1496 | 0.271 | 0.999 | D | 0.646 | 0.439 | 0.541105671861 | gnomAD-4.0.0 | 2.05274E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69854E-06 | 0 | 0 |
| E/D | 5958 |
Ig-43 |
40 | rs2080287202 |
0.3346 | None | 0.999 | N | 0.498 | 0.228 | 0.349870743963 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/D | 5958 |
Ig-43 |
40 | rs2080287202 |
0.3346 | None | 0.999 | N | 0.498 | 0.228 | 0.349870743963 | gnomAD-4.0.0 | 4.95792E-06 | None | None | None | None | N | None | 1.33508E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93363E-06 | 0 | 0 |
| E/D | 6051 |
Ig-44 |
40 | None | 0.4573 | None | 0.999 | D | 0.491 | 0.207 | 0.375861065471 | gnomAD-4.0.0 | 1.59239E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85963E-06 | 0 | 0 |
| E/K | 6051 |
Ig-44 |
40 | rs532089368 |
0.428 | -0.438 | 0.999 | D | 0.622 | 0.39 | 0.486135451721 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 6051 |
Ig-44 |
40 | rs532089368 |
0.428 | -0.438 | 0.999 | D | 0.622 | 0.39 | 0.486135451721 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 6051 |
Ig-44 |
40 | rs532089368 |
0.428 | -0.438 | 0.999 | D | 0.622 | 0.39 | 0.486135451721 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/K | 6051 |
Ig-44 |
40 | rs532089368 |
0.428 | -0.438 | 0.999 | D | 0.622 | 0.39 | 0.486135451721 | gnomAD-4.0.0 | 2.56354E-06 | None | None | None | None | N | None | 0 | 3.39305E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 6331 |
Ig-47 |
40 | rs1198892837 |
0.0823 | -0.125 | 0.906 | N | 0.297 | 0.128 | 0.505885190548 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
| I/L | 6331 |
Ig-47 |
40 | rs1198892837 |
0.0823 | -0.125 | 0.906 | N | 0.297 | 0.128 | 0.505885190548 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/L | 6331 |
Ig-47 |
40 | rs1198892837 |
0.0823 | -0.125 | 0.906 | N | 0.297 | 0.128 | 0.505885190548 | gnomAD-4.0.0 | 3.72031E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23934E-06 | 0 | 1.60251E-05 |
| Q/H | 6424 |
Ig-48 |
40 | rs749497096 |
0.292 | -0.043 | 0.822 | N | 0.313 | 0.184 | 0.251116650651 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Q/H | 6424 |
Ig-48 |
40 | rs749497096 |
0.292 | -0.043 | 0.822 | N | 0.313 | 0.184 | 0.251116650651 | gnomAD-4.0.0 | 1.59234E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| E/K | 6707 |
Ig-51 |
41 | rs2079497465 |
0.1004 | None | 0.14 | N | 0.198 | 0.292 | 0.30212335484 | gnomAD-4.0.0 | 1.59256E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02755E-05 |
| Q/H | 6800 |
Ig-52 |
40 | None | 0.4186 | None | 0.966 | N | 0.375 | 0.229 | 0.313518423057 | gnomAD-4.0.0 | 1.59296E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86105E-06 | 0 | 0 |
| Q/K | 6800 |
Ig-52 |
40 | rs1345237907 |
0.1835 | 0.095 | 0.454 | N | 0.303 | 0.171 | 0.204665344411 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| Q/K | 6800 |
Ig-52 |
40 | rs1345237907 |
0.1835 | 0.095 | 0.454 | N | 0.303 | 0.171 | 0.204665344411 | gnomAD-4.0.0 | 1.59305E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86115E-06 | 0 | 0 |
| Q/P | 6800 |
Ig-52 |
40 | None | 0.079 | None | 0.966 | N | 0.365 | 0.298 | 0.4018988957 | gnomAD-4.0.0 | 1.59297E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86098E-06 | 0 | 0 |
| E/G | 6893 |
Ig-53 |
40 | rs2079188744 |
0.1324 | None | 0.722 | N | 0.401 | 0.323 | 0.421674004627 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/G | 6893 |
Ig-53 |
40 | rs2079188744 |
0.1324 | None | 0.722 | N | 0.401 | 0.323 | 0.421674004627 | gnomAD-4.0.0 | 6.57194E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47042E-05 | 0 | 0 |
| L/P | 6987 |
Ig-54 |
40 | rs375676942 |
0.0886 | -0.637 | 0.966 | N | 0.409 | 0.307 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 1.6533E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/P | 6987 |
Ig-54 |
40 | rs375676942 |
0.0886 | -0.637 | 0.966 | N | 0.409 | 0.307 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 1.44725E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 6987 |
Ig-54 |
40 | rs375676942 |
0.0886 | -0.637 | 0.966 | N | 0.409 | 0.307 | None | gnomAD-4.0.0 | 3.94348E-05 | None | None | None | None | N | None | 1.44725E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 7176 |
Ig-56 |
40 | rs2078807925 |
0.2686 | None | 1.0 | N | 0.676 | 0.589 | 0.565318601174 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| N/K | 7269 |
Ig-57 |
40 | rs78990961 |
0.1172 | 0.501 | None | N | 0.169 | 0.115 | 0.0482279557977 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/K | 7269 |
Ig-57 |
40 | rs78990961 |
0.1172 | 0.501 | None | N | 0.169 | 0.115 | 0.0482279557977 | gnomAD-4.0.0 | 6.36795E-06 | None | None | None | None | N | None | 0 | 9.15499E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 7362 |
Ig-58 |
40 | None | 0.418 | None | 0.998 | N | 0.529 | 0.299 | 0.391313282164 | gnomAD-4.0.0 | 1.59219E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85964E-06 | 0 | 0 |
| E/D | 7554 |
Ig-60 |
40 | rs879075975 |
0.1489 | None | 0.003 | D | 0.18 | 0.115 | 0.371344866733 | gnomAD-4.0.0 | 1.36866E-06 | None | None | None | None | N | None | 2.98918E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99619E-07 | 0 | 0 |
| E/K | 7648 |
Ig-61 |
41 | rs397517502 |
0.0875 | -0.001 | 0.079 | N | 0.207 | 0.237 | 0.314417295294 | gnomAD-2.1.1 | 2.86E-05 | None | None | None | None | N | None | 4.14E-05 | 2.83E-05 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 3.13E-05 | 0 |
| E/K | 7648 |
Ig-61 |
41 | rs397517502 |
0.0875 | -0.001 | 0.079 | N | 0.207 | 0.237 | 0.314417295294 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| E/K | 7648 |
Ig-61 |
41 | rs397517502 |
0.0875 | -0.001 | 0.079 | N | 0.207 | 0.237 | 0.314417295294 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/K | 7648 |
Ig-61 |
41 | rs397517502 |
0.0875 | -0.001 | 0.079 | N | 0.207 | 0.237 | 0.314417295294 | gnomAD-4.0.0 | 1.48778E-05 | None | None | None | None | N | None | 6.66649E-05 | 1.66694E-05 | None | 0 | 0 | None | 0 | 0 | 1.27196E-05 | 2.19732E-05 | 1.60149E-05 |
| E/K | 7834 |
Ig-63 |
40 | None | 0.204 | None | 0.036 | D | 0.302 | 0.136 | 0.220303561663 | gnomAD-4.0.0 | 1.59143E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85873E-06 | 0 | 0 |
| E/Q | 7928 |
Ig-64 |
40 | rs770121355 |
0.1387 | -0.439 | 0.689 | N | 0.243 | 0.302 | 0.329540904979 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| E/Q | 7928 |
Ig-64 |
40 | rs770121355 |
0.1387 | -0.439 | 0.689 | N | 0.243 | 0.302 | 0.329540904979 | gnomAD-4.0.0 | 4.77435E-06 | None | None | None | None | N | None | 0 | 2.28655E-05 | None | 0 | 0 | None | 0 | 0 | 5.71759E-06 | 0 | 0 |
| E/Q | 8024 |
Ig-65 |
40 | None | 0.104 | None | 0.939 | N | 0.548 | 0.216 | 0.28722502521 | gnomAD-4.0.0 | 8.40225E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 6.56251E-06 | 0 | 3.66327E-05 |
| E/D | 8117 |
Ig-66 |
40 | None | 0.4137 | None | 0.999 | N | 0.505 | 0.39 | 0.269111216191 | gnomAD-4.0.0 | 1.59135E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| L/R | 8210 |
Ig-67 |
40 | None | 0.0759 | None | 0.014 | N | 0.332 | 0.167 | 0.39619538035 | gnomAD-4.0.0 | 1.59139E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8585E-06 | 0 | 0 |
| L/I | 8399 |
Ig-69 |
40 | rs375788467 |
0.0972 | None | 0.802 | N | 0.265 | 0.158 | 0.415438038341 | gnomAD-4.0.0 | 1.59208E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85945E-06 | 0 | 0 |
| L/P | 8399 |
Ig-69 |
40 | rs2077698375 |
0.107 | None | 0.028 | N | 0.211 | 0.294 | 0.653004105721 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| L/V | 8399 |
Ig-69 |
40 | rs375788467 |
0.0927 | -0.218 | 0.636 | N | 0.248 | 0.15 | None | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | N | None | 1.24172E-04 | 8.51E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/V | 8399 |
Ig-69 |
40 | rs375788467 |
0.0927 | -0.218 | 0.636 | N | 0.248 | 0.15 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20726E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 8399 |
Ig-69 |
40 | rs375788467 |
0.0927 | -0.218 | 0.636 | N | 0.248 | 0.15 | None | gnomAD-4.0.0 | 1.40987E-05 | None | None | None | None | N | None | 1.35391E-04 | 5.08578E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 8495 |
Ig-70 |
40 | rs747674081 |
0.5118 | -1.169 | 1.0 | N | 0.667 | 0.598 | 0.51520462741 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| E/G | 8495 |
Ig-70 |
40 | rs747674081 |
0.5118 | -1.169 | 1.0 | N | 0.667 | 0.598 | 0.51520462741 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 8495 |
Ig-70 |
40 | rs747674081 |
0.5118 | -1.169 | 1.0 | N | 0.667 | 0.598 | 0.51520462741 | gnomAD-4.0.0 | 6.5703E-06 | None | None | None | None | N | None | 2.4115E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/V | 8495 |
Ig-70 |
40 | rs747674081 |
0.4037 | 0.09 | 0.999 | D | 0.733 | 0.555 | 0.566047931302 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22792E-04 | None | 0 | None | 0 | 0 | 0 |
| E/V | 8495 |
Ig-70 |
40 | rs747674081 |
0.4037 | 0.09 | 0.999 | D | 0.733 | 0.555 | 0.566047931302 | gnomAD-4.0.0 | 6.36626E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.10932E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 8682 |
Ig-72 |
40 | None | 0.1476 | None | 0.031 | N | 0.111 | 0.068 | 0.221734844693 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| E/A | 8775 |
Ig-73 |
40 | rs758590305 |
0.1832 | -0.516 | 0.884 | N | 0.521 | 0.377 | 0.413113201963 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| E/A | 8775 |
Ig-73 |
40 | rs758590305 |
0.1832 | -0.516 | 0.884 | N | 0.521 | 0.377 | 0.413113201963 | gnomAD-4.0.0 | 1.59164E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85884E-06 | 0 | 0 |
| E/D | 8775 |
Ig-73 |
40 | None | 0.1024 | None | 0.288 | N | 0.484 | 0.166 | 0.282575091529 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| E/K | 8869 |
Ig-74 |
40 | rs375373507 |
0.1386 | 0.198 | 0.698 | N | 0.549 | 0.159 | None | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.45E-05 | 0 |
| E/K | 8869 |
Ig-74 |
40 | rs375373507 |
0.1386 | 0.198 | 0.698 | N | 0.549 | 0.159 | None | gnomAD-4.0.0 | 5.47442E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29675E-06 | 0 | 1.65706E-05 |
| E/K | 8965 |
Ig-75 |
40 | rs200325324 |
0.0763 | 0.467 | 0.805 | N | 0.543 | 0.199 | None | gnomAD-2.1.1 | 7.17E-05 | None | None | None | None | N | None | 1.2444E-04 | 0 | None | 0 | 0 | None | 1.31631E-04 | None | 1.60179E-04 | 6.27E-05 | 1.41044E-04 |
| E/K | 8965 |
Ig-75 |
40 | rs200325324 |
0.0763 | 0.467 | 0.805 | N | 0.543 | 0.199 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 2.07555E-04 | 0 |
| E/K | 8965 |
Ig-75 |
40 | rs200325324 |
0.0763 | 0.467 | 0.805 | N | 0.543 | 0.199 | None | gnomAD-4.0.0 | 4.83579E-05 | None | None | None | None | N | None | 2.67137E-05 | 0 | None | 0 | 0 | None | 2.50063E-04 | 0 | 3.5609E-05 | 1.75956E-04 | 3.2039E-05 |
| E/G | 9058 |
Ig-76 |
40 | None | 0.2668 | None | 0.999 | N | 0.647 | 0.589 | 0.672538118423 | gnomAD-4.0.0 | 6.84235E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99481E-07 | 0 | 0 |
| E/Q | 9058 |
Ig-76 |
40 | rs2154296273 |
0.1121 | None | 0.916 | N | 0.287 | 0.239 | 0.3691244813 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/S | 9151 |
Ig-77 |
40 | rs752655439 |
0.0628 | 0.001 | 0.028 | N | 0.197 | 0.1 | 0.115124310173 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| N/S | 9151 |
Ig-77 |
40 | rs752655439 |
0.0628 | 0.001 | 0.028 | N | 0.197 | 0.1 | 0.115124310173 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14422E-04 | 0 |
| N/S | 9151 |
Ig-77 |
40 | rs752655439 |
0.0628 | 0.001 | 0.028 | N | 0.197 | 0.1 | 0.115124310173 | gnomAD-4.0.0 | 8.67595E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.53711E-04 | 0 |
| E/D | 9436 |
Ig-80 |
40 | rs906433178 |
0.1305 | None | 0.003 | None | 0.145 | 0.099 | 0.270447802918 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 1.30907E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 9436 |
Ig-80 |
40 | rs906433178 |
0.1305 | None | 0.003 | None | 0.145 | 0.099 | 0.270447802918 | gnomAD-4.0.0 | 1.85895E-06 | None | None | None | None | N | None | 0 | 5.0005E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 9436 |
Ig-80 |
40 | None | 0.2094 | None | 0.034 | None | 0.249 | 0.127 | 0.251639045875 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 9629 |
Ig-82 |
40 | None | 0.5819 | None | 0.998 | None | 0.578 | 0.384 | 0.440077040801 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/R | 9738 |
Ig-83 |
41 | rs1370390355 |
0.5385 | 0.28 | 0.997 | None | 0.573 | 0.402 | 0.363751660372 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Q/R | 9738 |
Ig-83 |
41 | rs1370390355 |
0.5385 | 0.28 | 0.997 | None | 0.573 | 0.402 | 0.363751660372 | gnomAD-4.0.0 | 1.59106E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| I/L | 10027 |
Ig-85 |
39 | None | 0.0844 | None | None | None | 0.103 | 0.086 | 0.31077124679 | gnomAD-4.0.0 | 1.59086E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| I/T | 10027 |
Ig-85 |
39 | rs751219454 |
0.2654 | -0.865 | 0.007 | None | 0.297 | 0.08 | 0.597704877147 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.85E-06 | 0 |
| I/T | 10027 |
Ig-85 |
39 | rs751219454 |
0.2654 | -0.865 | 0.007 | None | 0.297 | 0.08 | 0.597704877147 | gnomAD-4.0.0 | 1.59087E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8575E-06 | 0 | 0 |
| I/N | 13818 |
Ig-88 |
39 | rs929168416 |
0.5915 | -0.147 | 0.772 | N | 0.538 | 0.149 | 0.379881503574 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| I/N | 13818 |
Ig-88 |
39 | rs929168416 |
0.5915 | -0.147 | 0.772 | N | 0.538 | 0.149 | 0.379881503574 | gnomAD-4.0.0 | 6.84444E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15974E-05 | 0 |
| I/T | 13818 |
Ig-88 |
39 | rs929168416 |
0.321 | None | 0.491 | N | 0.448 | 0.204 | 0.264081493735 | gnomAD-4.0.0 | 2.05333E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69895E-06 | 0 | 0 |
| E/D | 13912 |
Ig-89 |
37 | rs779199526 |
0.5049 | -0.78 | 0.709 | D | 0.473 | 0.124 | 0.219573609325 | gnomAD-2.1.1 | 4.59E-06 | None | None | None | None | N | None | 0 | 3.25E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/F | 14003 |
Ig-90 |
39 | rs767585297 |
0.3393 | -0.723 | 0.437 | N | 0.338 | 0.046 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.47E-05 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| L/F | 14003 |
Ig-90 |
39 | rs767585297 |
0.3393 | -0.723 | 0.437 | N | 0.338 | 0.046 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07469E-04 | 0 |
| L/F | 14003 |
Ig-90 |
39 | rs767585297 |
0.3393 | -0.723 | 0.437 | N | 0.338 | 0.046 | None | gnomAD-4.0.0 | 6.41248E-06 | None | None | None | None | N | None | 1.69279E-05 | 1.69848E-05 | None | 0 | 0 | None | 0 | 0 | 2.39519E-06 | 1.3425E-05 | 2.84787E-05 |
| L/P | 14003 |
Ig-90 |
39 | rs1162691488 |
0.4426 | -0.547 | 0.828 | N | 0.574 | 0.269 | 0.415055319159 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| L/P | 14003 |
Ig-90 |
39 | rs1162691488 |
0.4426 | -0.547 | 0.828 | N | 0.574 | 0.269 | 0.415055319159 | gnomAD-4.0.0 | 2.05369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.48367E-05 | 0 |
| L/R | 14003 |
Ig-90 |
39 | None | 0.6287 | None | 0.612 | N | 0.506 | 0.198 | 0.398133443147 | gnomAD-4.0.0 | 6.84563E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73732E-04 | 0 | 0 | 0 |
| I/T | 14091 |
Ig-91 |
38 | None | 0.3641 | None | 0.98 | N | 0.485 | 0.351 | 0.723184643479 | gnomAD-4.0.0 | 1.5922E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85999E-06 | 0 | 0 |
| I/V | 14091 |
Ig-91 |
38 | None | 0.1014 | None | 0.4 | N | 0.208 | 0.093 | 0.51721326083 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| K/N | 14180 |
Ig-92 |
39 | None | 0.6742 | None | 0.982 | N | 0.573 | 0.35 | 0.350088858571 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/A | 14268 |
Ig-93 |
38 | None | 0.1836 | None | 0.999 | D | 0.678 | 0.456 | 0.612639375224 | gnomAD-4.0.0 | 6.8438E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9959E-07 | 0 | 0 |
| E/Q | 14268 |
Ig-93 |
38 | None | 0.25 | None | 1.0 | D | 0.618 | 0.388 | 0.460526725402 | gnomAD-4.0.0 | 2.05315E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69877E-06 | 0 | 0 |
| E/V | 14268 |
Ig-93 |
38 | None | 0.2244 | None | 1.0 | D | 0.691 | 0.489 | 0.737197789486 | gnomAD-4.0.0 | 6.8438E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15939E-05 | 0 |
| P/A | 14357 |
Ig-94 |
39 | rs750958593 |
0.0885 | None | 0.07 | N | 0.291 | 0.13 | 0.134241683229 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/A | 14357 |
Ig-94 |
39 | rs750958593 |
0.0885 | None | 0.07 | N | 0.291 | 0.13 | 0.134241683229 | gnomAD-4.0.0 | 3.10034E-06 | None | None | None | None | N | None | 2.6718E-05 | 0 | None | 0 | 2.23874E-05 | None | 0 | 0 | 1.69579E-06 | 0 | 0 |
| P/S | 14357 |
Ig-94 |
39 | rs750958593 |
0.1437 | -0.592 | 0.146 | N | 0.305 | 0.245 | 0.148003135375 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.65E-05 | 0 | 0 |
| P/S | 14357 |
Ig-94 |
39 | rs750958593 |
0.1437 | -0.592 | 0.146 | N | 0.305 | 0.245 | 0.148003135375 | gnomAD-4.0.0 | 1.36926E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87399E-05 | 0 | 0 | 1.16122E-05 | 0 |
| P/T | 14357 |
Ig-94 |
39 | None | 0.0922 | -0.479 | 0.002 | N | 0.148 | 0.107 | 0.156986980423 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| P/T | 14357 |
Ig-94 |
39 | None | 0.0922 | -0.479 | 0.002 | N | 0.148 | 0.107 | 0.156986980423 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/T | 14357 |
Ig-94 |
39 | None | 0.0922 | -0.479 | 0.002 | N | 0.148 | 0.107 | 0.156986980423 | gnomAD-4.0.0 | 6.57549E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47059E-05 | 0 | 0 |
| E/D | 14446 |
Ig-95 |
39 | rs766663791 |
0.3183 | -0.548 | 0.999 | D | 0.497 | 0.239 | 0.253205268125 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| E/D | 14446 |
Ig-95 |
39 | rs766663791 |
0.3183 | -0.548 | 0.999 | D | 0.497 | 0.239 | 0.253205268125 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| E/K | 14446 |
Ig-95 |
39 | rs774470098 |
0.2455 | 0.211 | 0.999 | D | 0.637 | 0.411 | 0.534572409765 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 8.96E-06 | 0 |
| E/K | 14446 |
Ig-95 |
39 | rs774470098 |
0.2455 | 0.211 | 0.999 | D | 0.637 | 0.411 | 0.534572409765 | gnomAD-4.0.0 | 2.73732E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.63768E-05 | 0 |
| R/C | 14535 |
Ig-96 |
39 | rs12471771 |
0.2246 | -0.169 | 1.0 | D | 0.723 | 0.484 | None | gnomAD-2.1.1 | 2.14659E-02 | None | None | None | None | N | None | 2.72503E-03 | 1.64875E-01 | None | 0 | 1.05932E-04 | None | 6.75E-05 | None | 0 | 8.8E-05 | 1.61429E-02 |
| R/C | 14535 |
Ig-96 |
39 | rs12471771 |
0.2246 | -0.169 | 1.0 | D | 0.723 | 0.484 | None | gnomAD-3.1.2 | 9.76521E-03 | None | None | None | None | N | None | 2.34367E-03 | 8.81503E-02 | 0 | 0 | 1.93798E-04 | None | 0 | 0 | 2.79478E-04 | 0 | 1.20077E-02 |
| R/C | 14535 |
Ig-96 |
39 | rs12471771 |
0.2246 | -0.169 | 1.0 | D | 0.723 | 0.484 | None | 1000 genomes | 1.61741E-02 | None | None | None | None | N | None | 0 | 1.167E-01 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/C | 14535 |
Ig-96 |
39 | rs12471771 |
0.2246 | -0.169 | 1.0 | D | 0.723 | 0.484 | None | gnomAD-4.0.0 | 5.45174E-03 | None | None | None | None | N | None | 2.08222E-03 | 1.39179E-01 | None | 3.39628E-05 | 4.49539E-05 | None | 0 | 0 | 5.34863E-05 | 5.53489E-05 | 4.76588E-03 |
| R/H | 14535 |
Ig-96 |
39 | rs764250397 |
0.1403 | -0.762 | 1.0 | D | 0.743 | 0.436 | 0.435915822735 | gnomAD-2.1.1 | 2.48E-05 | None | None | None | None | N | None | 0 | 1.18441E-04 | None | 0 | 5.76E-05 | None | 0 | None | 0 | 9.12E-06 | 0 |
| R/H | 14535 |
Ig-96 |
39 | rs764250397 |
0.1403 | -0.762 | 1.0 | D | 0.743 | 0.436 | 0.435915822735 | gnomAD-4.0.0 | 1.09771E-05 | None | None | None | None | N | None | 0 | 9.04364E-05 | None | 0 | 5.08388E-05 | None | 0 | 0 | 8.10844E-06 | 1.16918E-05 | 0 |
| R/S | 14535 |
Ig-96 |
39 | rs12471771 |
0.5818 | -0.055 | 1.0 | D | 0.694 | 0.399 | 0.553103360211 | gnomAD-2.1.1 | 4.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.13E-06 | 0 |
| A/D | 14713 |
Ig-98 |
39 | rs750296112 |
0.234 | -0.564 | 0.437 | N | 0.466 | 0.195 | 0.232513804876 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| A/D | 14713 |
Ig-98 |
39 | rs750296112 |
0.234 | -0.564 | 0.437 | N | 0.466 | 0.195 | 0.232513804876 | gnomAD-4.0.0 | 3.18621E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86177E-06 | 0 | 3.02718E-05 |
| A/G | 14713 |
Ig-98 |
39 | None | 0.1522 | None | 0.181 | N | 0.309 | 0.167 | 0.124217242631 | gnomAD-4.0.0 | 1.5931E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43476E-05 | 0 |
| A/T | 14713 |
Ig-98 |
39 | rs1476356250 |
0.0812 | None | 0.003 | N | 0.213 | 0.108 | 0.104622674875 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 14713 |
Ig-98 |
39 | rs1476356250 |
0.0812 | None | 0.003 | N | 0.213 | 0.108 | 0.104622674875 | gnomAD-4.0.0 | 2.48017E-06 | None | None | None | None | N | None | 1.33622E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54392E-06 | 0 | 0 |
| K/E | 14802 |
Ig-99 |
38 | None | 0.265 | None | 0.992 | N | 0.52 | 0.347 | 0.371718192555 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| E/V | 15069 |
Ig-102 |
39 | rs114331773 |
0.3277 | 0.317 | 1.0 | N | 0.694 | 0.503 | None | gnomAD-2.1.1 | 6.41614E-03 | None | None | None | None | N | None | 5.5689E-02 | 4.00182E-03 | None | 1.69672E-02 | 0 | None | 2.28833E-04 | None | 0 | 6.68807E-04 | 5.06757E-03 |
| E/V | 15069 |
Ig-102 |
39 | rs114331773 |
0.3277 | 0.317 | 1.0 | N | 0.694 | 0.503 | None | gnomAD-3.1.2 | 1.6895E-02 | None | None | None | None | N | None | 5.52224E-02 | 9.39924E-03 | 0 | 1.50029E-02 | 0 | None | 0 | 1.26582E-02 | 6.92317E-04 | 0 | 1.67785E-02 |
| E/V | 15069 |
Ig-102 |
39 | rs114331773 |
0.3277 | 0.317 | 1.0 | N | 0.694 | 0.503 | None | 1000 genomes | 1.69728E-02 | None | None | None | None | N | None | 6.05E-02 | 7.2E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/V | 15069 |
Ig-102 |
39 | rs114331773 |
0.3277 | 0.317 | 1.0 | N | 0.694 | 0.503 | None | gnomAD-4.0.0 | 3.79652E-03 | None | None | None | None | N | None | 5.59651E-02 | 5.77977E-03 | None | 1.68121E-02 | 0 | None | 3.1249E-05 | 9.41837E-03 | 5.16493E-04 | 2.63568E-04 | 6.34514E-03 |
| T/I | 15158 |
Ig-103 |
39 | rs371879778 |
0.0756 | -0.07 | None | N | 0.19 | 0.117 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 1.24244E-04 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/I | 15158 |
Ig-103 |
39 | rs371879778 |
0.0756 | -0.07 | None | N | 0.19 | 0.117 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 7.25E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.42E-05 | 0 | 0 |
| T/I | 15158 |
Ig-103 |
39 | rs371879778 |
0.0756 | -0.07 | None | N | 0.19 | 0.117 | None | gnomAD-4.0.0 | 1.24058E-05 | None | None | None | None | N | None | 5.34817E-05 | 3.34627E-05 | None | 0 | 0 | None | 0 | 0 | 1.01772E-05 | 2.19698E-05 | 0 |
| A/G | 15246 |
Ig-104 |
39 | None | 0.1949 | None | 0.309 | N | 0.301 | 0.252 | 0.385743280973 | gnomAD-4.0.0 | 6.84668E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.999E-07 | 0 | 0 |
| E/D | 15340 |
Ig-105 |
39 | rs1576546728 |
0.1455 | None | 0.979 | D | 0.469 | 0.287 | 0.415820034956 | gnomAD-4.0.0 | 1.36953E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80008E-06 | 0 | 0 |
| V/A | 15518 |
Ig-107 |
39 | None | 0.152 | None | 0.01 | N | 0.217 | 0.133 | 0.583928190899 | gnomAD-4.0.0 | 1.59394E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86418E-06 | 0 | 0 |
| V/F | 15518 |
Ig-107 |
39 | None | 0.1961 | None | 0.171 | N | 0.431 | 0.069 | 0.584551062954 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| V/I | 15518 |
Ig-107 |
39 | None | 0.0643 | None | None | N | 0.135 | 0.099 | 0.356484672536 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| P/L | 15607 |
Ig-108 |
40 | None | 0.0675 | None | 0.012 | N | 0.325 | 0.159 | 0.421799068777 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 1.01626E-03 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 16002 |
Ig-109 |
35 | None | 0.1409 | None | 0.001 | N | 0.095 | 0.082 | 0.468168183122 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| I/F | 16298 |
Ig-110 |
37 | rs778200357 |
0.199 | -0.652 | 0.029 | N | 0.319 | 0.09 | 0.503186968135 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 1.16353E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/F | 16298 |
Ig-110 |
37 | rs778200357 |
0.199 | -0.652 | 0.029 | N | 0.319 | 0.09 | 0.503186968135 | gnomAD-4.0.0 | 7.96968E-06 | None | None | None | None | N | None | 0 | 1.14563E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 16994 |
Ig-111 |
40 | rs1230487887 |
0.1069 | None | 0.004 | D | 0.281 | 0.087 | 0.115124310173 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/D | 16994 |
Ig-111 |
40 | rs1230487887 |
0.1069 | None | 0.004 | D | 0.281 | 0.087 | 0.115124310173 | gnomAD-4.0.0 | 6.57999E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47202E-05 | 0 | 0 |
| V/L | 17287 |
Ig-112 |
37 | rs1333508634 |
0.1327 | -0.057 | 0.02 | N | 0.747 | 0.09 | 0.266843984389 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.65E-05 | None | 0 | None | 0 | 0 | 0 |
| E/K | 17712 |
Ig-113 |
36 | None | 0.1 | None | 0.007 | D | 0.193 | 0.241 | 0.343101102393 | gnomAD-4.0.0 | 1.59239E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86087E-06 | 0 | 0 |
| A/T | 18418 |
Ig-115 |
37 | rs536719544 |
0.1298 | -0.841 | 1.0 | N | 0.659 | 0.308 | 0.3691244813 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23864E-04 | None | 0 | None | 0 | 0 | 0 |
| A/T | 18418 |
Ig-115 |
37 | rs536719544 |
0.1298 | -0.841 | 1.0 | N | 0.659 | 0.308 | 0.3691244813 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94175E-04 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 18418 |
Ig-115 |
37 | rs536719544 |
0.1298 | -0.841 | 1.0 | N | 0.659 | 0.308 | 0.3691244813 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| A/T | 18418 |
Ig-115 |
37 | rs536719544 |
0.1298 | -0.841 | 1.0 | N | 0.659 | 0.308 | 0.3691244813 | gnomAD-4.0.0 | 3.84818E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.29963E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 18724 |
Ig-116 |
37 | rs1559671221 |
0.1128 | None | 0.012 | N | 0.329 | 0.173 | 0.243972157842 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| K/E | 18724 |
Ig-116 |
37 | rs1559671221 |
0.1128 | None | 0.012 | N | 0.329 | 0.173 | 0.243972157842 | gnomAD-4.0.0 | 2.7383E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.5993E-06 | 0 | 0 |
| K/R | 18724 |
Ig-116 |
37 | rs201091423 |
0.0745 | 0.182 | None | N | 0.231 | 0.087 | None | gnomAD-2.1.1 | 5.37E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.0973E-04 | 0 |
| K/R | 18724 |
Ig-116 |
37 | rs201091423 |
0.0745 | 0.182 | None | N | 0.231 | 0.087 | None | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.17689E-04 | 0 | 0 |
| K/R | 18724 |
Ig-116 |
37 | rs201091423 |
0.0745 | 0.182 | None | N | 0.231 | 0.087 | None | gnomAD-4.0.0 | 4.21579E-05 | None | None | None | None | N | None | 2.66702E-05 | 1.66806E-05 | None | 0 | 0 | None | 1.56235E-05 | 0 | 5.42682E-05 | 0 | 0 |
| K/T | 18724 |
Ig-116 |
37 | rs201091423 |
0.145 | 0.051 | 0.055 | N | 0.329 | 0.135 | 0.256283259241 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 1.2945E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| K/T | 18724 |
Ig-116 |
37 | rs201091423 |
0.145 | 0.051 | 0.055 | N | 0.329 | 0.135 | 0.256283259241 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/T | 18724 |
Ig-116 |
37 | rs201091423 |
0.145 | 0.051 | 0.055 | N | 0.329 | 0.135 | 0.256283259241 | gnomAD-4.0.0 | 1.79804E-05 | None | None | None | None | N | None | 2.67137E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.20463E-05 | 0 | 1.6019E-05 |
| T/A | 19132 |
Ig-117 |
38 | None | 0.0517 | None | None | N | 0.108 | 0.143 | 0.180583059064 | gnomAD-4.0.0 | 1.59218E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| T/S | 19132 |
Ig-117 |
38 | rs1245250461 |
0.073 | None | 0.001 | N | 0.233 | 0.108 | 0.214338557667 | gnomAD-4.0.0 | 2.05312E-06 | None | None | None | None | N | None | 0 | 2.23804E-05 | None | 0 | 0 | None | 0 | 0 | 8.99625E-07 | 0 | 1.657E-05 |
| D/H | 19426 |
Ig-118 |
36 | rs1408473678 |
0.1445 | None | 0.794 | D | 0.359 | 0.276 | 0.406531046227 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93874E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 19426 |
Ig-118 |
36 | rs1408473678 |
0.1445 | None | 0.794 | D | 0.359 | 0.276 | 0.406531046227 | gnomAD-4.0.0 | 6.57549E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93874E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 20118 |
Ig-120 |
39 | None | 0.1836 | None | 1.0 | N | 0.671 | 0.531 | 0.571137827458 | gnomAD-4.0.0 | 1.59228E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86028E-06 | 0 | 0 |
| D/G | 20811 |
Ig-122 |
43 | rs72646849 |
0.4121 | -0.863 | 1.0 | N | 0.722 | 0.471 | None | gnomAD-2.1.1 | 2.07201E-04 | None | None | None | None | N | None | 2.35635E-03 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/G | 20811 |
Ig-122 |
43 | rs72646849 |
0.4121 | -0.863 | 1.0 | N | 0.722 | 0.471 | None | gnomAD-3.1.2 | 5.45931E-04 | None | None | None | None | N | None | 1.88315E-03 | 1.96515E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 9.57854E-04 |
| D/G | 20811 |
Ig-122 |
43 | rs72646849 |
0.4121 | -0.863 | 1.0 | N | 0.722 | 0.471 | None | 1000 genomes | 1.39776E-03 | None | None | None | None | N | None | 5.3E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/G | 20811 |
Ig-122 |
43 | rs72646849 |
0.4121 | -0.863 | 1.0 | N | 0.722 | 0.471 | None | gnomAD-4.0.0 | 1.09093E-04 | None | None | None | None | N | None | 2.1335E-03 | 1.0003E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60102E-04 |
| D/N | 20811 |
Ig-122 |
43 | rs1476150726 |
0.1684 | -0.288 | 1.0 | N | 0.648 | 0.36 | 0.485634191555 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/N | 20811 |
Ig-122 |
43 | rs1476150726 |
0.1684 | -0.288 | 1.0 | N | 0.648 | 0.36 | 0.485634191555 | gnomAD-4.0.0 | 3.18468E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86673E-05 | 0 |
| D/A | 21214 |
Ig-123 |
38 | rs779686062 |
0.4021 | -0.074 | 1.0 | N | 0.733 | 0.545 | 0.486282253068 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| D/A | 21214 |
Ig-123 |
38 | rs779686062 |
0.4021 | -0.074 | 1.0 | N | 0.733 | 0.545 | 0.486282253068 | gnomAD-4.0.0 | 1.2322E-05 | None | None | None | None | I | None | 2.99168E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.25959E-05 | 0 | 4.97298E-05 |
| D/G | 21214 |
Ig-123 |
38 | None | 0.367 | None | 1.0 | D | 0.714 | 0.539 | 0.413891365518 | gnomAD-4.0.0 | 6.84554E-07 | None | None | None | None | I | None | 2.99168E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/N | 21214 |
Ig-123 |
38 | rs746677565 |
0.2208 | 0.217 | 1.0 | N | 0.638 | 0.411 | 0.374255764437 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/S | 22301 |
Ig-126 |
37 | rs772823241 |
0.1 | 0.046 | 0.822 | N | 0.423 | 0.268 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 1.78E-05 | 0 |
| N/S | 22301 |
Ig-126 |
37 | rs772823241 |
0.1 | 0.046 | 0.822 | N | 0.423 | 0.268 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| N/S | 22301 |
Ig-126 |
37 | rs772823241 |
0.1 | 0.046 | 0.822 | N | 0.423 | 0.268 | None | gnomAD-4.0.0 | 3.03787E-05 | None | None | None | None | N | None | 1.33554E-05 | 0 | None | 0 | 2.23724E-05 | None | 0 | 0 | 3.90016E-05 | 0 | 1.60251E-05 |
| D/N | 22987 |
Ig-128 |
38 | rs749120610 |
0.0989 | 0.375 | 0.904 | N | 0.545 | 0.213 | 0.266843984389 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.68067E-04 | None | 0 | None | 0 | 0 | 0 |
| D/N | 22987 |
Ig-128 |
38 | rs749120610 |
0.0989 | 0.375 | 0.904 | N | 0.545 | 0.213 | 0.266843984389 | gnomAD-4.0.0 | 1.27391E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22408E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 24069 |
Ig-131 |
41 | None | 0.1287 | None | 0.645 | N | 0.527 | 0.494 | 0.509053020717 | gnomAD-4.0.0 | 1.59294E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78443E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 24755 |
Ig-133 |
40 | rs1708309108 |
0.1157 | None | 0.016 | N | 0.171 | 0.123 | 0.186928172975 | gnomAD-4.0.0 | 5.47455E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29715E-06 | 1.15953E-05 | 0 |
| P/T | 24755 |
Ig-133 |
40 | None | 0.0878 | None | 0.005 | N | 0.172 | 0.157 | 0.307648195649 | gnomAD-4.0.0 | 2.05296E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69878E-06 | 0 | 0 |
| P/L | 25837 |
Ig-136 |
40 | rs752618930 |
0.0746 | 0.059 | 0.454 | N | 0.43 | 0.297 | 0.560303992393 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| P/L | 25837 |
Ig-136 |
40 | rs752618930 |
0.0746 | 0.059 | 0.454 | N | 0.43 | 0.297 | 0.560303992393 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85981E-06 | 0 | 0 |
| P/R | 25837 |
Ig-136 |
40 | None | 0.1614 | None | 0.966 | N | 0.458 | 0.351 | 0.472102515431 | gnomAD-4.0.0 | 1.59203E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85981E-06 | 0 | 0 |
| E/K | 26233 |
Ig-137 |
41 | rs267599036 |
0.1151 | 0.165 | 0.892 | N | 0.534 | 0.371 | 0.51196500227 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 2.94E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 26233 |
Ig-137 |
41 | rs267599036 |
0.1151 | 0.165 | 0.892 | N | 0.534 | 0.371 | 0.51196500227 | gnomAD-4.0.0 | 1.60051E-06 | None | None | None | None | N | None | 0 | 2.31107E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 26632 |
Ig-138 |
39 | None | 0.115 | None | 0.722 | D | 0.511 | 0.372 | 0.411265580357 | gnomAD-4.0.0 | 1.20035E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31253E-06 | 0 | 0 |
| P/T | 26919 |
Ig-139 |
40 | rs879200886 |
0.0717 | None | 0.001 | N | 0.179 | 0.136 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.66E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/T | 26919 |
Ig-139 |
40 | rs879200886 |
0.0717 | None | 0.001 | N | 0.179 | 0.136 | None | gnomAD-4.0.0 | 2.63103E-05 | None | None | None | None | N | None | 9.6623E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 27315 |
Ig-140 |
38 | None | 0.1088 | None | 0.942 | N | 0.697 | 0.351 | 0.505946769237 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/S | 27715 |
Ig-141 |
40 | None | 0.084 | None | 0.012 | N | 0.283 | 0.196 | 0.585898889599 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/P | 28002 |
Ig-142 |
40 | rs369737884 |
0.0515 | None | None | N | 0.241 | 0.15 | None | gnomAD-4.0.0 | 1.59276E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86E-06 | 0 | 0 |
| T/S | 28002 |
Ig-142 |
40 | None | 0.0864 | None | None | N | 0.141 | 0.107 | 0.0884992946249 | gnomAD-4.0.0 | 1.59276E-06 | None | None | None | None | N | None | 0 | 2.29074E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 28397 |
Ig-143 |
40 | None | 0.1256 | None | 0.999 | N | 0.511 | 0.215 | 0.297375071883 | gnomAD-4.0.0 | 1.36841E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79889E-06 | 0 | 0 |
| D/E | 28794 |
Ig-144 |
40 | None | 0.2756 | None | 0.958 | N | 0.506 | 0.218 | 0.303453137403 | gnomAD-4.0.0 | 1.3824E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.81152E-06 | 0 | 0 |
| D/H | 28794 |
Ig-144 |
40 | None | 0.4862 | None | 0.998 | N | 0.704 | 0.451 | 0.40032279838 | gnomAD-4.0.0 | 1.63125E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.92543E-06 | 0 | 0 |
| D/V | 28794 |
Ig-144 |
40 | rs544440335 |
0.2921 | 0.569 | 0.994 | N | 0.701 | 0.543 | 0.612322911341 | gnomAD-2.1.1 | 4.23E-06 | None | None | None | None | N | None | 6.51E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/V | 28794 |
Ig-144 |
40 | rs544440335 |
0.2921 | 0.569 | 0.994 | N | 0.701 | 0.543 | 0.612322911341 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 28794 |
Ig-144 |
40 | rs544440335 |
0.2921 | 0.569 | 0.994 | N | 0.701 | 0.543 | 0.612322911341 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| D/V | 28794 |
Ig-144 |
40 | rs544440335 |
0.2921 | 0.569 | 0.994 | N | 0.701 | 0.543 | 0.612322911341 | gnomAD-4.0.0 | 6.56978E-06 | None | None | None | None | N | None | 2.40639E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/H | 29084 |
Ig-145 |
40 | rs370776552 |
0.1333 | 0.111 | 0.794 | D | 0.342 | 0.231 | None | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 1.66058E-04 |
| P/H | 29084 |
Ig-145 |
40 | rs370776552 |
0.1333 | 0.111 | 0.794 | D | 0.342 | 0.231 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/H | 29084 |
Ig-145 |
40 | rs370776552 |
0.1333 | 0.111 | 0.794 | D | 0.342 | 0.231 | None | gnomAD-4.0.0 | 6.1969E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.5627E-05 | 0 | 7.62824E-06 | 0 | 0 |
| P/L | 29084 |
Ig-145 |
40 | None | 0.0642 | None | 0.002 | N | 0.258 | 0.185 | 0.464183351471 | gnomAD-4.0.0 | 6.84174E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99429E-07 | 0 | 0 |
| N/K | 29879 |
Ig-147 |
38 | rs756747766 |
0.3271 | None | 0.999 | N | 0.585 | 0.234 | 0.264081493735 | gnomAD-4.0.0 | 6.86599E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.02019E-07 | 0 | 0 |
| N/T | 29879 |
Ig-147 |
38 | None | 0.1405 | None | 0.994 | N | 0.547 | 0.207 | 0.347438807231 | gnomAD-4.0.0 | 1.59533E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85811E-06 | 0 | 0 |
| P/L | 30171 |
Ig-148 |
40 | rs2154151253 |
0.1105 | None | 0.984 | D | 0.677 | 0.455 | 0.721402755317 | gnomAD-4.0.0 | 3.30137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.96937E-06 | 1.51713E-05 | 0 |
| P/T | 30171 |
Ig-148 |
40 | None | 0.1493 | None | 0.999 | D | 0.717 | 0.442 | 0.610711448424 | gnomAD-4.0.0 | 6.95148E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.1041E-07 | 0 | 0 |
| R/G | 31255 |
Ig-151 |
38 | rs1219872044 |
0.2748 | -0.042 | 0.98 | N | 0.555 | 0.351 | 0.363751660372 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| R/G | 31255 |
Ig-151 |
38 | rs1219872044 |
0.2748 | -0.042 | 0.98 | N | 0.555 | 0.351 | 0.363751660372 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/G | 31255 |
Ig-151 |
38 | rs1219872044 |
0.2748 | -0.042 | 0.98 | N | 0.555 | 0.351 | 0.363751660372 | gnomAD-4.0.0 | 2.56178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78531E-06 | 0 | 0 |
| R/K | 31255 |
Ig-151 |
38 | rs376833905 |
0.1042 | 0.377 | 0.122 | N | 0.238 | 0.14 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| R/K | 31255 |
Ig-151 |
38 | rs376833905 |
0.1042 | 0.377 | 0.122 | N | 0.238 | 0.14 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| R/K | 31255 |
Ig-151 |
38 | rs376833905 |
0.1042 | 0.377 | 0.122 | N | 0.238 | 0.14 | None | gnomAD-4.0.0 | 3.71815E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08547E-06 | 0 | 0 |
| E/A | 31655 |
Ig-152 |
35 | None | 0.1616 | None | 0.994 | N | 0.561 | 0.388 | 0.449474494731 | gnomAD-4.0.0 | 3.18252E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86549E-05 | 0 |
| E/D | 31655 |
Ig-152 |
35 | rs769555143 |
0.1713 | -0.005 | 0.998 | N | 0.543 | 0.196 | 0.386721274199 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/D | 31655 |
Ig-152 |
35 | rs769555143 |
0.1713 | -0.005 | 0.998 | N | 0.543 | 0.196 | 0.386721274199 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/D | 31655 |
Ig-152 |
35 | rs769555143 |
0.1713 | -0.005 | 0.998 | N | 0.543 | 0.196 | 0.386721274199 | gnomAD-4.0.0 | 2.47884E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69525E-06 | 2.19573E-05 | 0 |
| E/K | 31655 |
Ig-152 |
35 | None | 0.2766 | None | 0.998 | D | 0.549 | 0.345 | 0.42324137094 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/Q | 32346 |
Ig-154 |
40 | rs372803018 |
0.1727 | 0.194 | 1.0 | N | 0.713 | 0.435 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 32346 |
Ig-154 |
40 | rs372803018 |
0.1727 | 0.194 | 1.0 | N | 0.713 | 0.435 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 1.44837E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 32346 |
Ig-154 |
40 | rs372803018 |
0.1727 | 0.194 | 1.0 | N | 0.713 | 0.435 | None | gnomAD-4.0.0 | 5.57732E-06 | None | None | None | None | N | None | 1.06818E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47608E-07 | 0 | 0 |
| D/G | 32744 |
Ig-155 |
37 | rs1177553110 |
0.3932 | -0.087 | 1.0 | N | 0.681 | 0.471 | 0.467416895013 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| D/G | 32744 |
Ig-155 |
37 | rs1177553110 |
0.3932 | -0.087 | 1.0 | N | 0.681 | 0.471 | 0.467416895013 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 32744 |
Ig-155 |
37 | rs1177553110 |
0.3932 | -0.087 | 1.0 | N | 0.681 | 0.471 | 0.467416895013 | gnomAD-4.0.0 | 4.33773E-06 | None | None | None | None | N | None | 0 | 1.66706E-05 | None | 0 | 0 | None | 0 | 0 | 5.08562E-06 | 0 | 0 |
| D/N | 32744 |
Ig-155 |
37 | None | 0.1594 | None | 1.0 | N | 0.641 | 0.341 | 0.432936702747 | gnomAD-4.0.0 | 1.59121E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77316E-05 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 32744 |
Ig-155 |
37 | rs1177553110 |
0.3162 | 0.518 | 1.0 | N | 0.729 | 0.502 | 0.617760060724 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/V | 32744 |
Ig-155 |
37 | rs1177553110 |
0.3162 | 0.518 | 1.0 | N | 0.729 | 0.502 | 0.617760060724 | gnomAD-4.0.0 | 6.84201E-07 | None | None | None | None | N | None | 0 | 2.23634E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 33140 |
Ig-156 |
40 | None | 0.6361 | None | 1.0 | N | 0.675 | 0.501 | 0.554156219314 | gnomAD-4.0.0 | 1.36846E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87315E-05 | 0 | 0 | 1.15934E-05 | 0 |
| E/K | 33140 |
Ig-156 |
40 | None | 0.5463 | None | 0.997 | N | 0.607 | 0.488 | 0.435152311215 | gnomAD-4.0.0 | 6.84232E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15942E-05 | 0 |
| E/Q | 33140 |
Ig-156 |
40 | None | 0.3436 | None | 0.999 | N | 0.586 | 0.364 | 0.501247319706 | gnomAD-4.0.0 | 6.84232E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99486E-07 | 0 | 0 |
| L/F | 33635 |
Ig-159 |
40 | rs879048474 |
0.5503 | -0.666 | 0.999 | D | 0.703 | 0.213 | None | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| L/F | 33635 |
Ig-159 |
40 | rs879048474 |
0.5503 | -0.666 | 0.999 | D | 0.703 | 0.213 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/F | 33635 |
Ig-159 |
40 | rs879048474 |
0.5503 | -0.666 | 0.999 | D | 0.703 | 0.213 | None | gnomAD-4.0.0 | 4.33796E-06 | None | None | None | None | N | None | 1.33522E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08569E-06 | 0 | 0 |
| K/N | 34297 |
Ig-161 |
40 | rs1019464699 |
0.625 | 0.058 | 0.982 | N | 0.672 | 0.347 | 0.29132392195 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| K/N | 34297 |
Ig-161 |
40 | rs1019464699 |
0.625 | 0.058 | 0.982 | N | 0.672 | 0.347 | 0.29132392195 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/N | 34297 |
Ig-161 |
40 | rs1019464699 |
0.625 | 0.058 | 0.982 | N | 0.672 | 0.347 | 0.29132392195 | gnomAD-4.0.0 | 2.02984E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40981E-06 | 0 | 0 |
| P/S | 34402 |
Ig-162 |
40 | rs1361480669 |
0.1709 | None | 0.58 | N | 0.299 | 0.29 | 0.329540904979 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| E/Q | 34981 |
Ig-163 |
40 | None | 0.2531 | None | 0.509 | N | 0.233 | 0.129 | 0.250579442822 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 35168 |
Ig-164 |
40 | rs1382618116 |
0.1242 | None | 0.007 | N | 0.167 | 0.071 | 0.442363741745 | gnomAD-4.0.0 | 1.59087E-06 | None | None | None | None | N | None | 5.65227E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 35168 |
Ig-164 |
40 | rs1382618116 |
0.1118 | -0.528 | 0.371 | N | 0.268 | 0.14 | 0.512539161327 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| V/M | 35168 |
Ig-164 |
40 | rs1382618116 |
0.1118 | -0.528 | 0.371 | N | 0.268 | 0.14 | 0.512539161327 | gnomAD-4.0.0 | 3.18174E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86541E-05 | 0 |
| K/E | 35325 |
Ig-165 |
40 | None | 0.2531 | None | 0.089 | N | 0.547 | 0.266 | 0.321672782286 | gnomAD-4.0.0 | 6.84134E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99391E-07 | 0 | 0 |
| K/Q | 35325 |
Ig-165 |
40 | None | 0.1703 | None | 0.407 | N | 0.6 | 0.225 | 0.32053947749 | gnomAD-4.0.0 | 6.84134E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99391E-07 | 0 | 0 |
| A/V | 35459 |
Ig-166 |
40 | rs879170800 |
0.0978 | None | None | N | 0.252 | 0.056 | 0.238705975628 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/V | 35459 |
Ig-166 |
40 | rs879170800 |
0.0978 | None | None | N | 0.252 | 0.056 | 0.238705975628 | gnomAD-4.0.0 | 9.32468E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46404E-05 | 1.46576E-05 | 0 |
| P/A | 35741 |
Ig-168 |
40 | rs1455118621 |
0.1362 | None | 0.826 | N | 0.332 | 0.267 | 0.306053231325 | gnomAD-4.0.0 | 1.37828E-06 | None | None | None | None | N | None | 6.06502E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 35741 |
Ig-168 |
40 | rs371210082 |
0.2109 | 0.094 | 0.704 | N | 0.381 | 0.321 | None | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.15E-06 | 0 |
| P/L | 35741 |
Ig-168 |
40 | rs371210082 |
0.2109 | 0.094 | 0.704 | N | 0.381 | 0.321 | None | gnomAD-4.0.0 | 5.51422E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.2372E-06 | 0 | 0 |
| P/R | 35741 |
Ig-168 |
40 | rs371210082 |
0.336 | None | 0.988 | N | 0.422 | 0.419 | 0.580315741719 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/R | 35741 |
Ig-168 |
40 | rs371210082 |
0.336 | None | 0.988 | N | 0.422 | 0.419 | 0.580315741719 | gnomAD-4.0.0 | 6.57186E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46994E-05 | 0 | 0 |
| P/S | 35741 |
Ig-168 |
40 | rs1455118621 |
0.2687 | -0.77 | 0.852 | N | 0.318 | 0.245 | 0.332133492242 | gnomAD-2.1.1 | 4.14E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.15E-06 | 0 |
| P/S | 35741 |
Ig-168 |
40 | rs1455118621 |
0.2687 | -0.77 | 0.852 | N | 0.318 | 0.245 | 0.332133492242 | gnomAD-4.0.0 | 1.37828E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80901E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.