Structural position:

  • Domain Type: Ig
  • Aligned Position: 70
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
T/A 48 Ig-1 43 None 0.0802 None None N 0.091 0.13 0.0954503805726 gnomAD-4.0.0 2.73628E-06 None None None 0.043(TCAP) N None 2.98686E-05 0 None 0 0 None 0 0 1.79858E-06 0 1.65579E-05
T/I 48 Ig-1 43 rs1295047971 0.2762 -0.176 0.128 N 0.278 0.311 0.442363741745 gnomAD-2.1.1 3.98E-06 None None None -0.067(TCAP) N None 0 0 None 0 5.45E-05 None 0 None 0 0 0
T/I 48 Ig-1 43 rs1295047971 0.2762 -0.176 0.128 N 0.278 0.311 0.442363741745 gnomAD-4.0.0 1.20032E-06 None None None -0.067(TCAP) N None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
T/P 48 Ig-1 43 None 0.0927 None None N 0.154 0.256 0.183819452728 gnomAD-4.0.0 6.84069E-07 None None None -0.021(TCAP) N None 0 0 None 0 2.52029E-05 None 0 0 0 0 0
S/N 146 Ig-2 43 rs1029708061 0.3255 0.058 0.004 N 0.213 0.233 0.167679373172 gnomAD-2.1.1 3.98E-06 None None None -0.705(TCAP) N None 0 0 None 0 0 None 0 None 0 8.8E-06 0
S/N 146 Ig-2 43 rs1029708061 0.3255 0.058 0.004 N 0.213 0.233 0.167679373172 gnomAD-4.0.0 3.4203E-06 None None None -0.705(TCAP) N None 2.98686E-05 0 None 0 0 None 0 0 3.59718E-06 0 0
S/R 146 Ig-2 43 None 0.8958 None 0.993 N 0.556 0.585 0.550088011563 gnomAD-4.0.0 3.42031E-06 None None None -0.407(TCAP) N None 0 0 None 0 0 None 0 0 4.49648E-06 0 0
S/R 985 Ig-3 43 None 0.824 None 0.009 N 0.231 0.333 0.271763555656 gnomAD-4.0.0 1.59053E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85657E-06 0 0
T/A 1124 Ig-4 43 rs2092846515 0.1071 None 0.223 N 0.473 0.139 0.149567049428 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 6.17284E-04 0 0 0
T/S 1124 Ig-4 43 None 0.0962 None 0.004 N 0.329 0.135 0.12205267543 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31253E-06 0 0
H/P 1333 Ig-5 43 rs768478889 0.0745 0.904 0.001 N 0.136 0.264 None gnomAD-2.1.1 4E-06 None None None None N None 6.16E-05 0 None 0 0 None 0 None 0 0 0
H/P 1333 Ig-5 43 rs768478889 0.0745 0.904 0.001 N 0.136 0.264 None gnomAD-4.0.0 1.36835E-06 None None None None N None 5.9755E-05 0 None 0 0 None 0 0 0 0 0
H/R 1333 Ig-5 43 rs768478889 0.1352 -0.078 0.002 N 0.154 0.13 0.115124310173 gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 8.87E-06 0
H/R 1333 Ig-5 43 rs768478889 0.1352 -0.078 0.002 N 0.154 0.13 0.115124310173 gnomAD-4.0.0 2.7367E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99347E-07 3.4785E-05 0
N/S 1499 Ig-6 43 rs745448931 0.1075 0.038 0.905 N 0.292 0.19 0.208816687407 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/S 1499 Ig-6 43 rs745448931 0.1075 0.038 0.905 N 0.292 0.19 0.208816687407 gnomAD-4.0.0 2.0525E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79871E-06 1.1595E-05 0
P/L 1598 Ig-7 43 None 0.5073 None 0.999 D 0.751 0.479 0.814722147942 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 1598 Ig-7 43 rs778940810 0.3966 -2.215 0.957 N 0.338 0.398 0.497021753114 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
P/S 1598 Ig-7 43 rs778940810 0.3966 -2.215 0.957 N 0.338 0.398 0.497021753114 gnomAD-4.0.0 3.42052E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59731E-06 0 1.65585E-05
A/T 1747 Ig-8 45 rs935944166 0.3153 -0.39 1.0 N 0.61 0.266 0.358540694251 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
A/T 1747 Ig-8 45 rs935944166 0.3153 -0.39 1.0 N 0.61 0.266 0.358540694251 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78011E-04
A/T 1747 Ig-8 45 rs935944166 0.3153 -0.39 1.0 N 0.61 0.266 0.358540694251 gnomAD-4.0.0 4.33709E-06 None None None None N None 0 0 None 0 0 None 0 0 5.08465E-06 0 1.60041E-05
K/T 1883 Ig-9 43 None 0.8562 None 1.0 N 0.653 0.53 0.516381326315 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/L 2120 Ig-10 43 rs141142920 0.3996 0.122 0.983 N 0.499 0.373 0.497613835824 gnomAD-2.1.1 3.02765E-04 None None None None N None 0 0 None 0 0 None 2.48236E-03 None 0 0 0
R/L 2120 Ig-10 43 rs141142920 0.3996 0.122 0.983 N 0.499 0.373 0.497613835824 gnomAD-3.1.2 5.92E-05 None None None None N None 0 0 0 0 0 None 0 0 0 1.86258E-03 0
R/L 2120 Ig-10 43 rs141142920 0.3996 0.122 0.983 N 0.499 0.373 0.497613835824 1000 genomes 9.98403E-04 None None None None N None 0 0 None None 0 0 None None None 5.1E-03 None
R/L 2120 Ig-10 43 rs141142920 0.3996 0.122 0.983 N 0.499 0.373 0.497613835824 gnomAD-4.0.0 1.20821E-04 None None None None N None 0 0 None 0 0 None 0 0 0 2.00909E-03 1.91988E-04
R/P 2120 Ig-10 43 rs141142920 0.4181 -0.094 0.998 N 0.467 0.404 0.384086055536 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
R/P 2120 Ig-10 43 rs141142920 0.4181 -0.094 0.998 N 0.467 0.404 0.384086055536 gnomAD-4.0.0 6.84126E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99308E-07 0 0
R/Q 2120 Ig-10 43 None 0.1432 -0.493 0.985 N 0.476 0.272 None gnomAD-2.1.1 1.38103E-04 None None None None N None 8.01E-05 1.97919E-04 None 0 5.03E-05 None 3.27E-05 None 3.98E-05 2.01657E-04 1.3885E-04
R/Q 2120 Ig-10 43 None 0.1432 -0.493 0.985 N 0.476 0.272 None gnomAD-3.1.2 3.28697E-04 None None None None N None 2.41E-05 2.09644E-03 0 0 0 None 0 0 2.49941E-04 0 0
R/Q 2120 Ig-10 43 None 0.1432 -0.493 0.985 N 0.476 0.272 None gnomAD-4.0.0 1.49953E-04 None None None None N None 1.33504E-05 6.67134E-04 None 0 2.23045E-05 None 4.68809E-05 3.28731E-04 1.55935E-04 1.09782E-05 1.60046E-04
R/W 2120 Ig-10 43 rs116158152 0.4462 -0.425 1.0 N 0.492 0.471 None gnomAD-2.1.1 1.99E-05 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 3.52E-05 0
R/W 2120 Ig-10 43 rs116158152 0.4462 -0.425 1.0 N 0.492 0.471 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 4.41E-05 0 0
R/W 2120 Ig-10 43 rs116158152 0.4462 -0.425 1.0 N 0.492 0.471 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
R/W 2120 Ig-10 43 rs116158152 0.4462 -0.425 1.0 N 0.492 0.471 None gnomAD-4.0.0 1.1153E-05 None None None None N None 0 0 None 0 0 None 0 0 1.27123E-05 1.09794E-05 3.2001E-05
E/D 2216 Ig-11 43 None 0.1077 None 0.003 N 0.133 0.167 0.0666544352282 gnomAD-4.0.0 1.59077E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
S/C 2308 Ig-12 42 None 0.1521 None 0.997 N 0.347 0.567 0.656132556037 gnomAD-4.0.0 6.84089E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99326E-07 0 0
S/P 2308 Ig-12 42 None 0.0822 None 0.005 N 0.138 0.313 0.220303561663 gnomAD-4.0.0 3.18114E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86549E-05 0
S/Y 2308 Ig-12 42 rs577966527 0.2162 -0.805 0.989 N 0.404 0.608 0.74608019428 gnomAD-2.1.1 1.42E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.11E-05 0
S/Y 2308 Ig-12 42 rs577966527 0.2162 -0.805 0.989 N 0.404 0.608 0.74608019428 gnomAD-3.1.2 3.94E-05 None None None None N None 0 0 0 0 0 None 0 0 8.82E-05 0 0
S/Y 2308 Ig-12 42 rs577966527 0.2162 -0.805 0.989 N 0.404 0.608 0.74608019428 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 1E-03 None None None 0 None
S/Y 2308 Ig-12 42 rs577966527 0.2162 -0.805 0.989 N 0.404 0.608 0.74608019428 gnomAD-4.0.0 3.40758E-05 None None None None N None 0 0 None 0 0 None 0 0 4.57638E-05 0 1.59985E-05
P/L 2397 Ig-13 42 None 0.1165 None 0.117 D 0.359 0.209 0.481321013822 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
P/R 2397 Ig-13 42 None 0.1586 None 0.317 N 0.373 0.195 0.32082282376 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 2487 Ig-14 43 rs759448340 0.1764 None 0.016 N 0.203 0.104 0.225902525712 gnomAD-4.0.0 1.59072E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85677E-06 0 0
P/T 2487 Ig-14 43 rs759448340 0.1312 -0.492 0.016 D 0.201 0.205 None gnomAD-2.1.1 1.42E-05 None None None None N None 1.60269E-04 0 None 0 0 None 0 None 0 0 0
P/T 2487 Ig-14 43 rs759448340 0.1312 -0.492 0.016 D 0.201 0.205 None gnomAD-3.1.2 3.29E-05 None None None None N None 1.20726E-04 0 0 0 0 None 0 0 0 0 0
P/T 2487 Ig-14 43 rs759448340 0.1312 -0.492 0.016 D 0.201 0.205 None gnomAD-4.0.0 1.15275E-05 None None None None N None 1.52279E-04 0 None 0 0 None 0 0 0 0 0
L/P 2661 Ig-16 41 rs781227223 0.142 -0.166 0.004 N 0.303 0.218 0.491455083755 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
L/P 2661 Ig-16 41 rs781227223 0.142 -0.166 0.004 N 0.303 0.218 0.491455083755 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 9.41E-05 0 0 0 0
L/P 2661 Ig-16 41 rs781227223 0.142 -0.166 0.004 N 0.303 0.218 0.491455083755 gnomAD-4.0.0 2.5612E-06 None None None None N None 0 0 None 0 0 None 1.56833E-05 0 0 1.33994E-05 0
S/P 2749 Ig-17 43 None 0.0749 None 0.003 N 0.249 0.223 0.218112801441 gnomAD-4.0.0 1.59049E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85649E-06 0 0
P/L 2836 Ig-18 42 rs1310170063 0.183 -0.145 0.896 N 0.506 0.343 0.683537019701 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/L 2836 Ig-18 42 rs1310170063 0.183 -0.145 0.896 N 0.506 0.343 0.683537019701 gnomAD-4.0.0 1.59046E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/R 2836 Ig-18 42 rs1310170063 0.3198 None 0.938 D 0.571 0.364 0.58191536258 gnomAD-4.0.0 3.18092E-06 None None None None N None 0 0 None 4.76554E-05 0 None 0 0 2.85649E-06 0 0
P/T 2836 Ig-18 42 rs772547332 0.1449 -0.486 0.811 N 0.453 0.267 0.464528537357 gnomAD-2.1.1 7.08E-06 None None None None N None 0 0 None 0 0 None 0 None 7.96E-05 0 0
S/P 3010 Ig-20 42 None 0.2127 None 1.0 N 0.687 0.619 0.311387274539 gnomAD-4.0.0 1.5906E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85647E-06 0 0
I/N 3099 Ig-21 42 rs747584198 0.2264 -0.174 0.029 N 0.391 0.114 0.53586618445 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
I/N 3099 Ig-21 42 rs747584198 0.2264 -0.174 0.029 N 0.391 0.114 0.53586618445 gnomAD-4.0.0 1.59055E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85651E-06 0 0
I/V 3099 Ig-21 42 rs2090820350 0.0784 None None N 0.102 0.061 0.173771789658 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.54E-05 0 0 0 None 0 0 0 0 0
I/V 3099 Ig-21 42 rs2090820350 0.0784 None None N 0.102 0.061 0.173771789658 gnomAD-4.0.0 6.56927E-06 None None None None N None 0 6.54365E-05 None 0 0 None 0 0 0 0 0
F/S 3188 Ig-22 42 rs776753598 0.9465 -1.355 0.997 N 0.553 0.481 0.748638279011 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.82E-06 0
F/S 3188 Ig-22 42 rs776753598 0.9465 -1.355 0.997 N 0.553 0.481 0.748638279011 gnomAD-4.0.0 1.59057E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85657E-06 0 0
F/Y 3188 Ig-22 42 rs776753598 0.5104 -0.356 0.997 D 0.5 0.304 0.506373324096 gnomAD-2.1.1 3.98E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
F/Y 3188 Ig-22 42 rs776753598 0.5104 -0.356 0.997 D 0.5 0.304 0.506373324096 gnomAD-4.0.0 1.59057E-06 None None None None N None 0 2.28655E-05 None 0 0 None 0 0 0 0 0
T/A 3281 Ig-23 43 None 0.0678 None None N 0.119 0.156 0.18995819373 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/L 3386 Ig-24 42 rs2088233776 0.2061 None 0.994 N 0.571 0.468 0.72796072516 gnomAD-4.0.0 1.59082E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85698E-06 0 0
P/S 3386 Ig-24 42 None 0.1716 None 0.978 N 0.391 0.409 0.32053947749 gnomAD-4.0.0 1.59081E-06 None None None None N None 0 0 None 0 0 None 0 0 2.857E-06 0 0
P/L 3507 Ig-25 43 rs1161132850 0.3558 None None None None 0.335 None gnomAD-4.0.0 4.78932E-06 None None None None I None 0 0 None 0 0 None 0 0 6.29619E-06 0 0
P/S 3507 Ig-25 43 rs773449874 0.3105 -1.204 None None None 0.208 None gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.66E-05 0
P/S 3507 Ig-25 43 rs773449874 0.3105 -1.204 None None None 0.208 None gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 3507 Ig-25 43 rs773449874 0.3105 -1.204 None None None 0.208 None gnomAD-4.0.0 3.03655E-05 None None None None I None 1.33494E-05 0 None 0 0 None 0 0 4.06857E-05 0 0
E/G 3702 Ig-26 43 rs2086938615 0.0896 None None None None 0.104 None gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/R 3862 Ig-27 43 rs201652675 0.2641 0.251 0.627 N 0.373 0.196 0.33835085245 gnomAD-2.1.1 4.83E-05 None None None None I None 0 0 None 0 0 None 0 None 0 1.06697E-04 0
P/R 3862 Ig-27 43 rs201652675 0.2641 0.251 0.627 N 0.373 0.196 0.33835085245 gnomAD-3.1.2 5.26E-05 None None None None I None 0 0 0 0 0 None 0 0 1.17609E-04 0 0
P/R 3862 Ig-27 43 rs201652675 0.2641 0.251 0.627 N 0.373 0.196 0.33835085245 gnomAD-4.0.0 7.12636E-05 None None None None I None 0 0 None 0 0 None 0 0 9.74743E-05 0 0
P/S 3862 Ig-27 43 rs375406698 0.155 None None N 0.108 0.073 None gnomAD-4.0.0 1.36839E-06 None None None None I None 0 2.23624E-05 None 0 0 None 0 0 0 1.15931E-05 0
P/T 3862 Ig-27 43 rs375406698 0.1577 -0.251 0.001 N 0.11 0.064 0.242825505644 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.67E-05 0
P/T 3862 Ig-27 43 rs375406698 0.1577 -0.251 0.001 N 0.11 0.064 0.242825505644 gnomAD-3.1.2 1.31E-05 None None None None I None 0 6.55E-05 0 0 0 None 0 0 1.47E-05 0 0
P/T 3862 Ig-27 43 rs375406698 0.1577 -0.251 0.001 N 0.11 0.064 0.242825505644 gnomAD-4.0.0 1.79712E-05 None None None None I None 0 3.33467E-05 None 0 0 None 0 0 2.28855E-05 0 0
T/I 3980 Ig-28 43 rs372298992 0.3936 0.015 0.473 N 0.303 0.278 None gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
T/I 3980 Ig-28 43 rs372298992 0.3936 0.015 0.473 N 0.303 0.278 None gnomAD-4.0.0 1.59116E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85793E-06 0 0
T/S 3980 Ig-28 43 rs1278282821 0.1391 None 0.01 N 0.137 0.109 None gnomAD-2.1.1 4.02E-06 None None None None I None 6.48E-05 0 None 0 0 None 0 None 0 0 0
T/S 3980 Ig-28 43 rs1278282821 0.1391 None 0.01 N 0.137 0.109 None gnomAD-3.1.2 1.31E-05 None None None None I None 4.82E-05 0 0 0 0 None 0 0 0 0 0
T/S 3980 Ig-28 43 rs1278282821 0.1391 None 0.01 N 0.137 0.109 None gnomAD-4.0.0 3.84282E-06 None None None None I None 5.07168E-05 0 None 0 0 None 0 0 0 0 0
E/D 4742 Ig-30 43 None 0.1576 None 0.002 N 0.099 0.113 0.253205268125 gnomAD-4.0.0 1.5918E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85869E-06 0 0
E/K 4742 Ig-30 43 rs781746943 0.3085 0.63 0.379 N 0.283 0.273 0.12205267543 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 4.65E-05 0 0
P/H 4837 Ig-31 43 rs1291141509 0.1453 0.125 0.928 N 0.346 0.335 0.564429724435 gnomAD-2.1.1 8.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.77E-05 0
P/H 4837 Ig-31 43 rs1291141509 0.1453 0.125 0.928 N 0.346 0.335 0.564429724435 gnomAD-4.0.0 1.36837E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79889E-06 0 0
P/L 4837 Ig-31 43 None 0.0965 None 0.001 N 0.254 0.288 0.558499945537 gnomAD-4.0.0 3.42094E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49724E-06 0 0
P/A 4930 Ig-32 43 rs201744218 0.0465 -0.214 None N 0.127 0.093 0.272639205421 gnomAD-2.1.1 1.00026E-04 None None None None N None 0 7.64613E-04 None 9.67E-05 0 None 0 None 0 0 0
P/A 4930 Ig-32 43 rs201744218 0.0465 -0.214 None N 0.127 0.093 0.272639205421 gnomAD-3.1.2 1.1177E-04 None None None None N None 2.41E-05 9.82962E-04 0 0 0 None 0 0 0 0 4.78469E-04
P/A 4930 Ig-32 43 rs201744218 0.0465 -0.214 None N 0.127 0.093 0.272639205421 gnomAD-4.0.0 3.96638E-05 None None None None N None 1.33515E-05 8.16993E-04 None 3.37838E-05 0 None 0 0 5.08569E-06 0 1.121E-04
P/L 4930 Ig-32 43 None 0.0701 None 0.062 N 0.371 0.217 0.647688206944 gnomAD-4.0.0 1.59153E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02535E-05
P/T 4930 Ig-32 43 rs201744218 0.0636 -0.404 0.002 N 0.155 0.108 None gnomAD-2.1.1 1.46466E-04 None None None None N None 1.40542E-03 1.41595E-04 None 0 5.14E-05 None 0 None 0 0 1.40726E-04
P/T 4930 Ig-32 43 rs201744218 0.0636 -0.404 0.002 N 0.155 0.108 None gnomAD-3.1.2 4.86522E-04 None None None None N None 1.5932E-03 4.58655E-04 0 0 0 None 0 0 0 0 4.78469E-04
P/T 4930 Ig-32 43 rs201744218 0.0636 -0.404 0.002 N 0.155 0.108 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
P/T 4930 Ig-32 43 rs201744218 0.0636 -0.404 0.002 N 0.155 0.108 None gnomAD-4.0.0 1.0411E-04 None None None None N None 1.97281E-03 2.16674E-04 None 0 2.23045E-05 None 0 0 0 0 9.60523E-05
E/A 5024 Ig-33 44 None 0.1283 None 0.051 N 0.189 0.141 0.393006254552 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
E/G 5024 Ig-33 44 rs2081168482 0.1451 None 0.625 N 0.307 0.217 0.515995215087 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 5024 Ig-33 44 rs750031855 0.1413 0.099 0.801 N 0.217 0.224 0.430579932962 gnomAD-2.1.1 7.15E-05 None None None None N None 0 0 None 0 7.18833E-04 None 1.30753E-04 None 0 1.56E-05 0
E/K 5024 Ig-33 44 rs750031855 0.1413 0.099 0.801 N 0.217 0.224 0.430579932962 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 5.77367E-04 None 0 0 0 2.07125E-04 0
E/K 5024 Ig-33 44 rs750031855 0.1413 0.099 0.801 N 0.217 0.224 0.430579932962 gnomAD-4.0.0 1.92116E-05 None None None None N None 0 0 None 0 4.45951E-04 None 0 0 2.54286E-06 6.58762E-05 3.20266E-05
S/N 5117 Ig-34 43 None 0.1752 None 0.99 D 0.46 0.283 0.327952845175 gnomAD-4.0.0 3.18324E-06 None None None None N None 0 0 None 0 0 None 1.88303E-05 0 2.85892E-06 0 0
E/Q 5210 Ig-35 43 None 0.1649 None 0.904 D 0.396 0.232 0.400033932507 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/S 5303 Ig-36 43 rs72648934 0.0881 -0.399 0.001 N 0.113 0.065 0.134241683229 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
A/S 5303 Ig-36 43 rs72648934 0.0881 -0.399 0.001 N 0.113 0.065 0.134241683229 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/S 5303 Ig-36 43 rs72648934 0.0881 -0.399 0.001 N 0.113 0.065 0.134241683229 gnomAD-4.0.0 4.33804E-06 None None None None N None 0 0 None 0 0 None 0 0 5.08573E-06 0 1.60123E-05
A/T 5303 Ig-36 43 rs72648934 0.1127 -0.392 0.035 N 0.161 0.096 0.171388866994 gnomAD-2.1.1 3.22E-05 None None None None N None 0 0 None 0 0 None 1.96091E-04 None 0 1.78E-05 0
A/T 5303 Ig-36 43 rs72648934 0.1127 -0.392 0.035 N 0.161 0.096 0.171388866994 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 0 6.21375E-04 0
A/T 5303 Ig-36 43 rs72648934 0.1127 -0.392 0.035 N 0.161 0.096 0.171388866994 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
A/T 5303 Ig-36 43 rs72648934 0.1127 -0.392 0.035 N 0.161 0.096 0.171388866994 gnomAD-4.0.0 1.98296E-05 None None None None N None 0 0 None 0 0 None 0 0 8.47629E-06 2.30572E-04 1.60067E-05
S/F 5492 Ig-38 43 rs1162269961 0.255 None 0.984 N 0.569 0.495 0.752771577926 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 1.92976E-04 None 0 0 0 0 0
S/F 5492 Ig-38 43 rs1162269961 0.255 None 0.984 N 0.569 0.495 0.752771577926 gnomAD-4.0.0 2.56274E-06 None None None None I None 0 0 None 0 2.4273E-05 None 0 0 0 1.34005E-05 0
S/P 5492 Ig-38 43 None 0.0804 None 0.984 N 0.428 0.345 0.346544149963 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
E/D 5586 Ig-39 44 None 0.0937 None 0.001 N 0.135 0.1 0.208816687407 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 6.07533E-05 0
E/K 5586 Ig-39 44 rs2080668204 0.1359 None 0.324 D 0.226 0.247 0.377976839388 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
E/Q 5586 Ig-39 44 rs2080668204 0.1235 None 0.324 D 0.298 0.212 0.306053231325 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/Q 5586 Ig-39 44 rs2080668204 0.1235 None 0.324 D 0.298 0.212 0.306053231325 gnomAD-4.0.0 6.57272E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47024E-05 0 0
E/K 5772 Ig-41 43 rs763931240 0.1279 0.833 0.994 D 0.49 0.32 0.483816155017 gnomAD-2.1.1 4.02E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
E/K 5772 Ig-41 43 rs763931240 0.1279 0.833 0.994 D 0.49 0.32 0.483816155017 gnomAD-3.1.2 6.57E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
E/K 5772 Ig-41 43 rs763931240 0.1279 0.833 0.994 D 0.49 0.32 0.483816155017 gnomAD-4.0.0 2.56244E-06 None None None None I None 0 3.39098E-05 None 0 0 None 0 0 0 0 0
L/P 5865 Ig-42 43 rs1372169677 0.0773 -0.289 0.001 N 0.231 0.307 0.597289040352 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
L/P 5865 Ig-42 43 rs1372169677 0.0773 -0.289 0.001 N 0.231 0.307 0.597289040352 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
L/P 5865 Ig-42 43 rs1372169677 0.0773 -0.289 0.001 N 0.231 0.307 0.597289040352 gnomAD-4.0.0 3.84379E-06 None None None None N None 5.07563E-05 0 None 0 0 None 0 0 0 0 0
L/V 5865 Ig-42 43 None 0.0745 None 0.324 N 0.251 0.169 0.190952846119 gnomAD-4.0.0 1.59145E-06 None None None None N None 0 2.28697E-05 None 0 0 None 0 0 0 0 0
A/T 5961 Ig-43 43 rs2080285790 0.0899 None 0.103 N 0.212 0.089 0.203808441222 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
A/T 5961 Ig-43 43 rs2080285790 0.0899 None 0.103 N 0.212 0.089 0.203808441222 gnomAD-4.0.0 6.57428E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 4.78469E-04
A/V 5961 Ig-43 43 rs909915866 0.1373 None 0.896 N 0.369 0.235 0.374434639691 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
S/G 6241 Ig-46 43 None 0.0761 None 0.99 D 0.382 0.437 0.365703291355 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/N 6241 Ig-46 43 None 0.1095 None 0.999 N 0.441 0.312 0.343788945184 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/R 6241 Ig-46 43 rs1015857991 0.4141 -0.018 0.999 D 0.527 0.528 0.421427970867 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
S/R 6241 Ig-46 43 rs1015857991 0.4141 -0.018 0.999 D 0.527 0.528 0.421427970867 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/R 6241 Ig-46 43 rs1015857991 0.4141 -0.018 0.999 D 0.527 0.528 0.421427970867 gnomAD-4.0.0 4.33843E-06 None None None None N None 4.00641E-05 0 None 0 0 None 0 0 3.3908E-06 0 0
E/D 6334 Ig-47 43 rs755041916 0.1325 0.041 0.001 N 0.152 0.073 0.313210971179 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 3.28E-05 None 0 0 0
E/D 6334 Ig-47 43 rs755041916 0.1325 0.041 0.001 N 0.152 0.073 0.313210971179 gnomAD-4.0.0 6.84613E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.16063E-05 0
E/G 6334 Ig-47 43 rs2079893948 0.1069 None 0.193 N 0.344 0.277 0.49741755877 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
P/H 6427 Ig-48 43 None 0.4669 None 1.0 N 0.542 0.457 0.740245011328 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
P/S 6427 Ig-48 43 rs770277382 0.195 -0.205 0.592 N 0.312 0.241 0.289098819767 gnomAD-2.1.1 4.03E-05 None None None None N None 0 2.90884E-04 None 0 0 None 0 None 0 0 0
P/S 6427 Ig-48 43 rs770277382 0.195 -0.205 0.592 N 0.312 0.241 0.289098819767 gnomAD-3.1.2 2.63E-05 None None None None N None 0 2.62226E-04 0 0 0 None 0 0 0 0 0
P/S 6427 Ig-48 43 rs770277382 0.195 -0.205 0.592 N 0.312 0.241 0.289098819767 gnomAD-4.0.0 1.92304E-05 None None None None N None 0 2.546E-04 None 0 0 None 0 0 0 0 0
P/T 6427 Ig-48 43 None 0.2317 None 0.978 N 0.379 0.345 0.565975473979 gnomAD-4.0.0 1.59247E-06 None None None None N None 0 0 None 0 2.77855E-05 None 0 0 0 0 0
T/A 6523 Ig-49 43 rs1560756818 0.0604 None None N 0.087 0.109 0.0986583533028 gnomAD-4.0.0 2.73774E-06 None None None None I None 0 0 None 0 0 None 0 0 0 4.63854E-05 0
T/P 6523 Ig-49 43 None 0.0673 None 0.301 N 0.317 0.272 0.250579442822 gnomAD-4.0.0 6.84435E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99675E-07 0 0
S/I 6803 Ig-52 43 rs2079258083 0.3163 None 0.998 N 0.405 0.523 0.734682175585 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/I 6803 Ig-52 43 rs2079258083 0.3163 None 0.998 N 0.405 0.523 0.734682175585 gnomAD-4.0.0 6.57618E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47033E-05 0 0
E/D 6897 Ig-53 44 None 0.2739 None 0.031 N 0.16 0.062 0.177238962908 gnomAD-4.0.0 1.36881E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79934E-06 0 0
S/G 6990 Ig-54 43 rs1467185474 0.0979 -0.248 0.994 N 0.39 0.383 0.267299060538 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
S/G 6990 Ig-54 43 rs1467185474 0.0979 -0.248 0.994 N 0.39 0.383 0.267299060538 gnomAD-4.0.0 3.18377E-06 None None None None N None 5.66316E-05 0 None 0 0 None 0 0 2.85959E-06 0 0
S/G 7086 Ig-55 43 rs777135698 0.117 0.083 0.98 N 0.312 0.405 None gnomAD-2.1.1 8.06E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 8.91E-06 0
S/G 7086 Ig-55 43 rs777135698 0.117 0.083 0.98 N 0.312 0.405 None gnomAD-3.1.2 1.97E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 1.47E-05 0 0
S/G 7086 Ig-55 43 rs777135698 0.117 0.083 0.98 N 0.312 0.405 None gnomAD-4.0.0 3.71864E-06 None None None None N None 4.00459E-05 0 None 0 0 None 0 0 2.54315E-06 0 0
S/I 7086 Ig-55 43 None 0.2605 None 0.606 N 0.279 0.366 0.616972202741 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/A 7272 Ig-57 43 rs747710632 0.0557 -0.238 None N 0.119 0.117 0.0297737177859 gnomAD-2.1.1 8.07E-06 None None None None N None 0 0 None 0 0 None 0 None 4.65E-05 8.93E-06 0
T/A 7272 Ig-57 43 rs747710632 0.0557 -0.238 None N 0.119 0.117 0.0297737177859 gnomAD-4.0.0 6.36776E-06 None None None None N None 0 0 None 0 0 None 5.65121E-05 0 2.85928E-06 0 0
T/S 7272 Ig-57 43 None 0.0745 None None N 0.092 0.088 0.0666544352282 gnomAD-4.0.0 1.59194E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85928E-06 0 0
D/E 7461 Ig-59 43 rs376383610 0.2517 None 0.551 N 0.331 0.043 0.223847106136 gnomAD-4.0.0 1.36872E-06 None None None None N None 0 0 None 0 5.04159E-05 None 0 0 0 0 0
P/T 7557 Ig-60 43 rs758231381 0.0838 -0.12 0.001 N 0.145 0.179 0.313210971179 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
P/T 7557 Ig-60 43 rs758231381 0.0838 -0.12 0.001 N 0.145 0.179 0.313210971179 gnomAD-4.0.0 6.36752E-06 None None None None N None 0 0 None 0 0 None 0 0 0 5.73296E-05 0
E/G 7651 Ig-61 44 rs1461872954 0.1103 -0.791 0.248 N 0.241 0.22 0.402614778071 gnomAD-2.1.1 4.03E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
E/G 7651 Ig-61 44 rs1461872954 0.1103 -0.791 0.248 N 0.241 0.22 0.402614778071 gnomAD-3.1.2 2.63E-05 None None None None N None 9.65E-05 0 0 0 0 None 0 0 0 0 0
E/G 7651 Ig-61 44 rs1461872954 0.1103 -0.791 0.248 N 0.241 0.22 0.402614778071 gnomAD-4.0.0 5.57904E-06 None None None None N None 1.06803E-04 0 None 0 0 None 0 0 8.47909E-07 0 0
N/K 7744 Ig-62 43 rs72648972 0.5412 0.331 None N 0.161 0.136 0.225215365344 gnomAD-2.1.1 3.74668E-03 None None None None N None 8.2713E-04 1.1898E-03 None 9.96903E-03 7.70416E-04 None 1.89302E-02 None 1.60038E-04 2.00382E-03 4.08681E-03
N/K 7744 Ig-62 43 rs72648972 0.5412 0.331 None N 0.161 0.136 0.225215365344 gnomAD-3.1.2 1.97847E-03 None None None None N None 7.23764E-04 1.24508E-03 4.38597E-03 9.50461E-03 7.71903E-04 None 4.70633E-04 6.32911E-03 1.74964E-03 1.62027E-02 3.34288E-03
N/K 7744 Ig-62 43 rs72648972 0.5412 0.331 None N 0.161 0.136 0.225215365344 1000 genomes 4.99201E-03 None None None None N None 8E-04 4.3E-03 None None 0 4E-03 None None None 1.74E-02 None
N/K 7744 Ig-62 43 rs72648972 0.5412 0.331 None N 0.161 0.136 0.225215365344 gnomAD-4.0.0 2.52118E-03 None None None None N None 7.06497E-04 1.26713E-03 None 9.93512E-03 6.46657E-04 None 2.50008E-04 1.42055E-02 1.39198E-03 1.82317E-02 3.32981E-03
N/S 7744 Ig-62 43 rs757107171 0.0594 -0.043 None N 0.108 0.181 0.149567049428 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
N/S 7744 Ig-62 43 rs757107171 0.0594 -0.043 None N 0.108 0.181 0.149567049428 gnomAD-4.0.0 1.59181E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85935E-06 0 0
E/D 7838 Ig-63 44 None 0.2523 None None N 0.153 0.117 0.159798565429 gnomAD-4.0.0 1.59141E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85871E-06 0 0
E/K 7838 Ig-63 44 rs891050085 0.4398 0.11 0.38 N 0.323 0.368 0.348764635752 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
E/K 7838 Ig-63 44 rs891050085 0.4398 0.11 0.38 N 0.323 0.368 0.348764635752 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 4.79386E-04
E/K 7838 Ig-63 44 rs891050085 0.4398 0.11 0.38 N 0.323 0.368 0.348764635752 gnomAD-4.0.0 3.84346E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78677E-06 0 2.84495E-05
S/G 8027 Ig-65 43 None 0.0799 None 0.011 N 0.185 0.153 0.261217442401 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/R 8027 Ig-65 43 rs1229192464 0.279 0.008 0.984 D 0.415 0.4 0.445614145163 gnomAD-2.1.1 8.04E-06 None None None None I None 0 5.79E-05 None 0 0 None 0 None 0 0 0
S/R 8027 Ig-65 43 rs1229192464 0.279 0.008 0.984 D 0.415 0.4 0.445614145163 gnomAD-4.0.0 3.18242E-06 None None None None I None 0 4.57268E-05 None 0 0 None 0 0 0 0 0
S/T 8027 Ig-65 43 None 0.0776 None 0.946 N 0.371 0.306 0.335661160332 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 6.17284E-04 0 0 0
P/L 8120 Ig-66 43 None 0.0909 None 0.024 D 0.364 0.223 0.52535981233 gnomAD-4.0.0 6.15809E-06 None None None None N None 0 0 None 0 0 None 0 0 8.09546E-06 0 0
P/S 8120 Ig-66 43 rs745913661 0.0716 -0.074 None N 0.117 0.119 0.0551355673512 gnomAD-2.1.1 4.83E-05 None None None None N None 0 0 None 0 6.69195E-04 None 0 None 0 0 0
P/S 8120 Ig-66 43 rs745913661 0.0716 -0.074 None N 0.117 0.119 0.0551355673512 gnomAD-4.0.0 3.2843E-05 None None None None N None 0 0 None 0 1.20968E-03 None 0 0 0 0 0
Q/H 8213 Ig-67 43 rs397517510 0.1952 -0.161 0.002 N 0.171 0.078 0.128392430309 gnomAD-2.1.1 3.57E-05 None None None None I None 0 2.83E-05 None 0 0 None 0 None 0 7.05E-05 0
Q/H 8213 Ig-67 43 rs397517510 0.1952 -0.161 0.002 N 0.171 0.078 0.128392430309 gnomAD-3.1.2 8.55E-05 None None None None I None 0 0 0 0 0 None 0 0 1.91165E-04 0 0
Q/H 8213 Ig-67 43 rs397517510 0.1952 -0.161 0.002 N 0.171 0.078 0.128392430309 gnomAD-4.0.0 1.05974E-04 None None None None I None 0 1.66756E-05 None 0 0 None 0 0 1.30537E-04 0 2.56205E-04
Q/K 8213 Ig-67 43 None 0.0968 None 0.183 D 0.199 0.265 0.212008924253 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
S/L 8306 Ig-68 43 rs776712129 0.1327 0.228 0.932 D 0.428 0.48 0.71767939224 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
S/L 8306 Ig-68 43 rs776712129 0.1327 0.228 0.932 D 0.428 0.48 0.71767939224 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/L 8306 Ig-68 43 rs776712129 0.1327 0.228 0.932 D 0.428 0.48 0.71767939224 gnomAD-4.0.0 1.36365E-05 None None None None N None 0 0 None 0 2.22826E-05 None 0 0 1.78009E-05 0 0
D/G 8402 Ig-69 43 rs954211095 0.2595 None 0.861 N 0.378 0.209 0.293502639404 gnomAD-4.0.0 1.59208E-06 None None None None I None 0 2.2877E-05 None 0 0 None 0 0 0 0 0
D/N 8402 Ig-69 43 None 0.1683 None 0.111 N 0.225 0.178 0.247322355667 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/A 8498 Ig-70 43 rs1225974862 0.0919 -0.136 0.001 N 0.186 0.147 0.191931220699 gnomAD-2.1.1 7.13E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
P/A 8498 Ig-70 43 rs1225974862 0.0919 -0.136 0.001 N 0.186 0.147 0.191931220699 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/A 8498 Ig-70 43 rs1225974862 0.0919 -0.136 0.001 N 0.186 0.147 0.191931220699 gnomAD-4.0.0 2.47906E-06 None None None None N None 4.00673E-05 0 None 0 0 None 0 0 0 0 1.60138E-05
S/G 8685 Ig-72 43 None 0.1224 None 0.938 N 0.203 0.293 0.376745185316 gnomAD-4.0.0 6.84234E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15945E-05 0
S/R 8685 Ig-72 43 rs878932254 0.8608 0.058 0.998 N 0.332 0.488 0.469826472337 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
S/R 8685 Ig-72 43 rs878932254 0.8608 0.058 0.998 N 0.332 0.488 0.469826472337 gnomAD-4.0.0 3.42117E-06 None None None None N None 0 0 None 0 0 None 0 0 4.49758E-06 0 0
S/T 8685 Ig-72 43 None 0.1207 None 0.491 D 0.192 0.179 0.311387274539 gnomAD-4.0.0 1.59143E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85881E-06 0 0
S/N 8968 Ig-75 43 None 0.1778 None 0.324 N 0.258 0.103 0.0920862733494 gnomAD-4.0.0 1.59227E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85954E-06 0 0
P/A 9061 Ig-76 43 rs772373852 0.0675 0.079 0.016 N 0.207 0.117 0.208000267992 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/A 9061 Ig-76 43 rs772373852 0.0675 0.079 0.016 N 0.207 0.117 0.208000267992 gnomAD-4.0.0 2.73692E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.63811E-05 0
P/Q 9061 Ig-76 43 None 0.1166 None 0.016 N 0.224 0.143 0.363751660372 gnomAD-4.0.0 2.05269E-06 None None None None N None 0 0 None 0 0 None 0 0 0 3.47826E-05 0
P/L 9154 Ig-77 43 None 0.0839 None 0.012 N 0.308 0.159 0.56713362702 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
P/S 9154 Ig-77 43 None 0.0786 None 0.012 N 0.336 0.07 0.245101548738 gnomAD-4.0.0 6.84188E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99446E-07 0 0
P/L 9247 Ig-78 43 rs775155957 0.168 0.06 0.042 N 0.347 0.164 0.538745750885 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/L 9247 Ig-78 43 rs775155957 0.168 0.06 0.042 N 0.347 0.164 0.538745750885 gnomAD-4.0.0 3.18257E-06 None None None None N None 0 4.57373E-05 None 0 0 None 0 0 0 0 0
P/S 9247 Ig-78 43 rs1475796244 0.105 -0.248 0.001 N 0.145 0.128 0.16115917748 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 0 None 0 None 2.87853E-04 0 0
P/S 9247 Ig-78 43 rs1475796244 0.105 -0.248 0.001 N 0.145 0.128 0.16115917748 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 9.43E-05 0 0 0 0
P/S 9247 Ig-78 43 rs1475796244 0.105 -0.248 0.001 N 0.145 0.128 0.16115917748 gnomAD-4.0.0 6.57428E-06 None None None None N None 0 0 None 0 0 None 9.42863E-05 0 0 0 0
S/N 9439 Ig-80 43 None 0.1316 None 0.642 None 0.215 0.265 0.32471235697 gnomAD-4.0.0 4.77295E-06 None None Phosphoserine None I None 0 0 None 0 0 None 0 0 8.57324E-06 0 0
P/L 9536 Ig-81 44 None 0.1278 None None None 0.19 0.191 0.492611691308 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/T 9536 Ig-81 44 rs201121983 0.0944 -0.222 0.001 None 0.147 0.13 0.28798054836 gnomAD-2.1.1 2.01E-05 None None None None I None 0 8.69E-05 None 0 0 None 3.27E-05 None 0 8.85E-06 0
P/T 9536 Ig-81 44 rs201121983 0.0944 -0.222 0.001 None 0.147 0.13 0.28798054836 gnomAD-3.1.2 3.94E-05 None None None None I None 0 1.96541E-04 0 0 0 None 0 0 2.94E-05 2.07039E-04 0
P/T 9536 Ig-81 44 rs201121983 0.0944 -0.222 0.001 None 0.147 0.13 0.28798054836 1000 genomes 5.99042E-04 None None None None I None 0 2.9E-03 None None 0 0 None None None 1E-03 None
P/T 9536 Ig-81 44 rs201121983 0.0944 -0.222 0.001 None 0.147 0.13 0.28798054836 gnomAD-4.0.0 3.96552E-05 None None None None I None 1.33259E-05 3.66654E-04 None 0 0 None 0 0 3.39034E-05 0 1.60041E-05
P/L 9632 Ig-82 43 rs1398429600 0.126 0.286 0.549 None 0.36 0.253 0.550210968228 gnomAD-2.1.1 8.03E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
P/L 9632 Ig-82 43 rs1398429600 0.126 0.286 0.549 None 0.36 0.253 0.550210968228 gnomAD-4.0.0 6.36436E-06 None None None None N None 0 9.14913E-05 None 0 0 None 0 0 0 0 0
P/S 9632 Ig-82 43 rs1223602495 0.1072 None 0.007 None 0.159 0.109 0.134241683229 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 9632 Ig-82 43 rs1223602495 0.1072 None 0.007 None 0.159 0.109 0.134241683229 gnomAD-4.0.0 1.15283E-05 None None None None N None 0 0 None 0 0 None 0 0 2.15338E-05 0 0
Q/H 9741 Ig-83 44 None 0.3249 None 0.002 None 0.11 0.134 0.380223377699 gnomAD-4.0.0 1.59103E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85788E-06 0 0
Q/K 9741 Ig-83 44 rs773039731 0.1654 0.165 0.425 None 0.225 0.32 0.351830644314 gnomAD-2.1.1 2.14E-05 None None None None N None 0 0 None 0 3.07188E-04 None 0 None 0 0 0
Q/K 9741 Ig-83 44 rs773039731 0.1654 0.165 0.425 None 0.225 0.32 0.351830644314 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 3.84911E-04 None 0 0 0 0 0
Q/K 9741 Ig-83 44 rs773039731 0.1654 0.165 0.425 None 0.225 0.32 0.351830644314 gnomAD-4.0.0 8.96769E-06 None None None None N None 0 0 None 0 1.45412E-04 None 0 0 0 0 2.84382E-05
P/L 9943 Ig-84 44 None 0.1758 None 0.042 None 0.333 0.13 0.428976297845 gnomAD-4.0.0 1.59486E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43649E-05 0
P/S 10030 Ig-85 42 rs368531555 0.4399 -0.374 0.642 None 0.313 0.153 None gnomAD-2.1.1 1.6E-05 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 2.65E-05 0
P/S 10030 Ig-85 42 rs368531555 0.4399 -0.374 0.642 None 0.313 0.153 None gnomAD-3.1.2 3.29E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 2.94E-05 0 0
P/S 10030 Ig-85 42 rs368531555 0.4399 -0.374 0.642 None 0.313 0.153 None gnomAD-4.0.0 3.90372E-05 None None None None N None 6.67432E-05 0 None 0 0 None 0 0 4.91577E-05 0 0
P/T 10030 Ig-85 42 rs368531555 0.3034 None 0.642 None 0.325 0.156 0.387202362727 gnomAD-4.0.0 6.84134E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99394E-07 0 0
E/Q 10119 Ig-86 42 rs778565859 0.5654 0.129 1.0 None 0.527 0.256 0.475034548194 gnomAD-2.1.1 9.23E-05 None None None None N None 0 6.66126E-04 None 0 0 None 0 None 0 0 0
E/Q 10119 Ig-86 42 rs778565859 0.5654 0.129 1.0 None 0.527 0.256 0.475034548194 gnomAD-4.0.0 1.64192E-05 None None None None N None 0 4.91906E-04 None 0 0 None 0 0 1.79878E-06 0 0
E/D 13728 Ig-87 45 rs2060464524 0.6215 None 0.999 N 0.457 0.218 0.296329037015 gnomAD-4.0.0 1.59193E-06 None None None None N None 0 0 None 0 0 None 0 2.41429E-04 0 0 0
E/G 13728 Ig-87 45 None 0.7782 None 1.0 N 0.602 0.479 0.484400871567 gnomAD-4.0.0 3.18382E-06 None None None None N None 0 2.28686E-05 None 0 0 None 0 0 2.85959E-06 0 0
E/K 13728 Ig-87 45 rs765483020 0.916 0.288 0.999 N 0.594 0.464 0.381916209588 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
E/K 13728 Ig-87 45 rs765483020 0.916 0.288 0.999 N 0.594 0.464 0.381916209588 gnomAD-4.0.0 2.73732E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99599E-07 3.4781E-05 0
E/K 13821 Ig-88 42 rs749586891 0.4154 -0.005 0.01 N 0.166 0.136 0.117506650769 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.63E-05 None 0 None 0 0 0
E/Q 13821 Ig-88 42 rs749586891 0.2724 -0.441 0.065 N 0.217 0.073 0.0716867268079 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
E/Q 13821 Ig-88 42 rs749586891 0.2724 -0.441 0.065 N 0.217 0.073 0.0716867268079 gnomAD-4.0.0 1.5925E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.4334E-05 0
A/V 13915 Ig-89 40 rs371426048 0.0786 -0.024 0.014 N 0.164 0.017 None gnomAD-2.1.1 6.9E-05 None None None None I None 0 1.95185E-04 None 0 6.36E-05 None 1.09186E-04 None 0 5.25E-05 0
A/V 13915 Ig-89 40 rs371426048 0.0786 -0.024 0.014 N 0.164 0.017 None gnomAD-3.1.2 3.29E-05 None None None None I None 2.42E-05 6.57E-05 0 0 0 None 0 0 2.94E-05 0 4.79846E-04
A/V 13915 Ig-89 40 rs371426048 0.0786 -0.024 0.014 N 0.164 0.017 None gnomAD-4.0.0 3.76528E-05 None None None None I None 4.01725E-05 1.58467E-04 None 0 2.26224E-05 None 0 0 2.65232E-05 1.46846E-04 4.85893E-05
P/L 14006 Ig-90 42 None 0.656 None 0.919 N 0.62 0.212 0.299086750705 gnomAD-4.0.0 3.60099E-06 None None None None N None 0 0 None 0 0 None 0 0 3.93752E-06 0 0
P/S 14006 Ig-90 42 None 0.6076 None 0.919 N 0.412 0.196 0.204665344411 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
S/P 14094 Ig-91 41 None 0.0863 None None N 0.155 0.163 0.0666544352282 gnomAD-4.0.0 1.3688E-06 None None None None N None 2.9915E-05 0 None 0 0 None 0 0 8.99659E-07 0 0
T/A 14183 Ig-92 42 rs72650081 0.0904 None 0.91 N 0.358 0.17 0.276482976112 gnomAD-4.0.0 2.73737E-06 None None None None N None 0 0 None 0 0 None 0 0 3.5985E-06 0 0
T/K 14183 Ig-92 42 None 0.2395 None 0.98 N 0.422 0.379 0.421920138742 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/R 14183 Ig-92 42 None 0.1926 None 0.998 N 0.469 0.379 0.501122797481 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 14271 Ig-93 41 None 0.1533 None 0.684 D 0.353 0.337 0.64185220107 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/D 14360 Ig-94 42 None 0.3297 -1.402 0.651 N 0.414 0.253 0.347217280506 gnomAD-2.1.1 4.05E-06 None None None None N None 0 2.93E-05 None 0 0 None 0 None 0 0 0
A/D 14360 Ig-94 42 None 0.3297 -1.402 0.651 N 0.414 0.253 0.347217280506 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.31062E-04 0 0 0 None 0 0 0 0 4.78927E-04
A/D 14360 Ig-94 42 None 0.3297 -1.402 0.651 N 0.414 0.253 0.347217280506 gnomAD-4.0.0 4.3449E-06 None None None None N None 0 5.02109E-05 None 0 0 None 0 0 2.5459E-06 0 1.60478E-05
A/V 14360 Ig-94 42 rs928035274 0.159 -0.554 0.791 N 0.255 0.169 0.239901079897 gnomAD-2.1.1 6.37E-05 None None None None N None 0 0 None 0 0 None 0 None 0 1.29618E-04 0
A/V 14360 Ig-94 42 rs928035274 0.159 -0.554 0.791 N 0.255 0.169 0.239901079897 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 0 None 0 0 5.88E-05 0 0
A/V 14360 Ig-94 42 rs928035274 0.159 -0.554 0.791 N 0.255 0.169 0.239901079897 gnomAD-4.0.0 3.1035E-06 None None None None N None 0 0 None 0 2.24145E-05 None 0 0 3.39453E-06 0 0
G/D 14449 Ig-95 42 rs1461692009 0.1544 -0.233 0.029 N 0.351 0.176 0.151104730317 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
G/D 14449 Ig-95 42 rs1461692009 0.1544 -0.233 0.029 N 0.351 0.176 0.151104730317 gnomAD-4.0.0 3.18383E-06 None None None None N None 0 0 None 0 2.77408E-05 None 0 0 0 0 3.02535E-05
G/R 14449 Ig-95 42 rs1485328319 0.1671 None 0.055 N 0.475 0.076 0.21737058555 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
G/R 14449 Ig-95 42 rs1485328319 0.1671 None 0.055 N 0.475 0.076 0.21737058555 gnomAD-4.0.0 1.2397E-06 None None None None N None 0 3.33622E-05 None 0 0 None 0 0 0 0 0
G/S 14449 Ig-95 42 rs1485328319 0.0736 None None N 0.139 0.106 0.0401082797425 gnomAD-4.0.0 1.36866E-06 None None None None N None 2.98954E-05 0 None 0 0 None 0 0 8.99619E-07 0 0
T/A 14538 Ig-96 42 None 0.0876 None 0.78 N 0.409 0.203 0.311387274539 gnomAD-4.0.0 4.80183E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87176E-06 0 6.07128E-05
T/I 14538 Ig-96 42 None 0.2207 None 0.984 N 0.419 0.451 0.488125499135 gnomAD-4.0.0 6.8594E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00836E-07 0 0
T/N 14538 Ig-96 42 None 0.1491 None 0.995 N 0.398 0.341 0.434606191737 gnomAD-4.0.0 6.8594E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00836E-07 0 0
P/S 14805 Ig-99 41 None 0.1114 None 1.0 N 0.717 0.325 0.362758974969 gnomAD-4.0.0 6.8475E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99965E-07 0 0
E/K 15072 Ig-102 42 rs963923376 0.1712 0.568 0.939 N 0.505 0.366 0.426551566703 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 8.95E-06 0
E/K 15072 Ig-102 42 rs963923376 0.1712 0.568 0.939 N 0.505 0.366 0.426551566703 gnomAD-4.0.0 2.73863E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99905E-07 2.31932E-05 1.65837E-05
S/C 15161 Ig-103 42 rs1469799928 0.1835 None 0.612 D 0.373 0.456 0.459100921832 gnomAD-4.0.0 1.36956E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79985E-06 0 0
S/P 15161 Ig-103 42 rs1191629167 0.0868 0.025 None N 0.141 0.156 0.132336055621 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
S/P 15161 Ig-103 42 rs1191629167 0.0868 0.025 None N 0.141 0.156 0.132336055621 gnomAD-4.0.0 1.59427E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86266E-06 0 0
S/Y 15161 Ig-103 42 rs1469799928 0.2289 -0.769 0.295 D 0.407 0.417 0.524741657026 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/Y 15161 Ig-103 42 rs1469799928 0.2289 -0.769 0.295 D 0.407 0.417 0.524741657026 gnomAD-4.0.0 6.8478E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15999E-05 0
D/H 15249 Ig-104 42 rs1467540790 0.5186 None 1.0 N 0.548 0.424 0.42324137094 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/H 15249 Ig-104 42 rs1467540790 0.5186 None 1.0 N 0.548 0.424 0.42324137094 gnomAD-4.0.0 6.58623E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47262E-05 0 0
D/N 15249 Ig-104 42 None 0.1718 None 0.989 N 0.424 0.32 0.413113201963 gnomAD-4.0.0 1.59361E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43345E-05 0
E/A 15432 Ig-106 42 None 0.1868 None 0.008 N 0.278 0.254 0.407632638399 gnomAD-4.0.0 6.49868E-06 None None None None N None 2.29073E-04 0 None 0 0 None 0 0 0 1.40127E-05 1.75759E-05
E/D 15432 Ig-106 42 None 0.276 None 0.008 N 0.251 0.079 0.502568190621 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/Q 15432 Ig-106 42 rs1319118967 0.2888 None 0.901 N 0.465 0.202 0.559427399277 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.57E-05 0 0 0 None 0 0 0 0 0
E/Q 15432 Ig-106 42 rs1319118967 0.2888 None 0.901 N 0.465 0.202 0.559427399277 gnomAD-4.0.0 1.95325E-06 None None None None N None 1.39051E-05 2.14298E-05 None 0 2.27386E-05 None 0 0 0 0 0
E/V 15432 Ig-106 42 rs1202126471 0.4126 None 0.82 D 0.482 0.372 0.636139071576 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
E/V 15432 Ig-106 42 rs1202126471 0.4126 None 0.82 D 0.482 0.372 0.636139071576 gnomAD-4.0.0 1.31626E-05 None None None None N None 4.82812E-05 0 None 0 0 None 0 0 0 0 0
Q/K 15521 Ig-107 42 rs758692633 0.1978 0.353 0.997 N 0.457 0.412 0.367042808489 gnomAD-2.1.1 1.07E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.35E-05 0
Q/K 15521 Ig-107 42 rs758692633 0.1978 0.353 0.997 N 0.457 0.412 0.367042808489 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.95E-05 0 0
Q/K 15521 Ig-107 42 rs758692633 0.1978 0.353 0.997 N 0.457 0.412 0.367042808489 gnomAD-4.0.0 1.31837E-05 None None None None N None 0 0 None 0 0 None 0 0 2.94742E-05 0 0
T/I 15610 Ig-108 43 rs748293286 0.1005 -0.067 0.317 N 0.354 0.121 0.346992582518 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 4.66E-05 0 0
T/R 16005 Ig-109 38 rs557711303 0.1304 0.135 0.029 N 0.311 0.08 0.337378238328 gnomAD-2.1.1 4.45E-05 None None None None N None 0 0 None 0 6.17769E-04 None 0 None 0 0 0
T/R 16005 Ig-109 38 rs557711303 0.1304 0.135 0.029 N 0.311 0.08 0.337378238328 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94704E-04 None 0 0 0 0 0
T/R 16005 Ig-109 38 rs557711303 0.1304 0.135 0.029 N 0.311 0.08 0.337378238328 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
T/R 16005 Ig-109 38 rs557711303 0.1304 0.135 0.029 N 0.311 0.08 0.337378238328 gnomAD-4.0.0 1.17816E-05 None None None None N None 0 0 None 0 4.02793E-04 None 0 0 0 0 1.6022E-05
Q/H 16301 Ig-110 40 rs886038833 0.2176 -0.494 0.56 N 0.189 0.059 0.39208347742 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
Q/H 16301 Ig-110 40 rs886038833 0.2176 -0.494 0.56 N 0.189 0.059 0.39208347742 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
Q/H 16301 Ig-110 40 rs886038833 0.2176 -0.494 0.56 N 0.189 0.059 0.39208347742 gnomAD-4.0.0 3.72147E-06 None None None None N None 1.3374E-05 0 None 0 0 None 0 0 4.24035E-06 0 0
A/V 16997 Ig-111 43 rs757016012 0.0944 -0.114 0.124 N 0.419 0.108 0.339316883193 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.67E-05 0
A/V 16997 Ig-111 43 rs757016012 0.0944 -0.114 0.124 N 0.419 0.108 0.339316883193 gnomAD-4.0.0 4.77973E-06 None None None None N None 0 0 None 0 0 None 0 0 8.586E-06 0 0
P/L 17290 Ig-112 40 None 0.2581 None 1.0 N 0.843 0.491 0.742616433148 gnomAD-4.0.0 1.36956E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7999E-06 0 0
P/S 17290 Ig-112 40 rs1481460924 0.2523 None 1.0 N 0.818 0.397 0.422883881359 gnomAD-4.0.0 3.42391E-06 None None None None N None 0 0 None 0 2.53498E-05 None 0 0 3.59984E-06 0 0
K/E 17715 Ig-113 39 None 0.1199 None 0.767 N 0.367 0.203 0.3085936734 gnomAD-4.0.0 1.59232E-06 None None None None N None 0 0 None 0 0 None 0 2.41546E-04 0 0 0
K/N 17715 Ig-113 39 rs2055193492 0.3117 None 0.999 N 0.593 0.3 0.349429436713 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/N 17715 Ig-113 39 rs2055193492 0.3117 None 0.999 N 0.593 0.3 0.349429436713 gnomAD-4.0.0 6.57843E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47202E-05 0 0
E/K 18431 Ig-115 50 rs756341923 0.1166 0.517 0.986 N 0.473 0.219 0.305410167561 gnomAD-2.1.1 1.22E-05 None None None None N None 0 0 None 1.0008E-04 0 None 0 None 0 1.79E-05 0
E/K 18431 Ig-115 50 rs756341923 0.1166 0.517 0.986 N 0.473 0.219 0.305410167561 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/K 18431 Ig-115 50 rs756341923 0.1166 0.517 0.986 N 0.473 0.219 0.305410167561 gnomAD-4.0.0 9.30744E-06 None None None None N None 2.67401E-05 0 None 6.77002E-05 0 None 0 0 8.48163E-06 0 1.60369E-05
Q/E 19135 Ig-117 41 None 0.0539 None None N 0.121 0.14 0.270001397563 gnomAD-4.0.0 1.59213E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85976E-06 0 0
Q/L 19135 Ig-117 41 None 0.0823 None 0.081 N 0.25 0.182 0.338110398507 gnomAD-4.0.0 1.36875E-06 None None None None N None 5.97836E-05 0 None 0 0 None 0 0 0 0 0
E/Q 19429 Ig-118 39 None 0.1242 None 0.31 N 0.19 0.176 0.346085882481 gnomAD-4.0.0 1.59204E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43287E-05 0
T/A 19829 Ig-119 40 rs1436610603 0.0547 -0.338 0.001 N 0.086 0.125 0.136095386433 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
T/A 19829 Ig-119 40 rs1436610603 0.0547 -0.338 0.001 N 0.086 0.125 0.136095386433 gnomAD-4.0.0 1.36864E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79919E-06 0 0
T/I 19829 Ig-119 40 rs754082474 0.0853 0.049 0.001 N 0.203 0.179 0.328486982098 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
T/I 19829 Ig-119 40 rs754082474 0.0853 0.049 0.001 N 0.203 0.179 0.328486982098 gnomAD-4.0.0 3.18372E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8595E-06 1.4332E-05 0
T/S 19829 Ig-119 40 rs754082474 0.0728 -0.371 0.042 N 0.221 0.114 0.139678290688 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
T/S 19829 Ig-119 40 rs754082474 0.0728 -0.371 0.042 N 0.221 0.114 0.139678290688 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.78469E-04
T/S 19829 Ig-119 40 rs754082474 0.0728 -0.371 0.042 N 0.221 0.114 0.139678290688 gnomAD-4.0.0 6.57687E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 4.78469E-04
R/Q 20519 Ig-121 41 rs727504191 0.0855 0.059 0.002 N 0.179 0.062 0.149567049428 gnomAD-2.1.1 5.26E-05 None None None None N None 0 3.20812E-04 None 0 0 None 3.3E-05 None 0 0 1.67392E-04
R/Q 20519 Ig-121 41 rs727504191 0.0855 0.059 0.002 N 0.179 0.062 0.149567049428 gnomAD-3.1.2 1.57845E-04 None None None None N None 0 1.57336E-03 0 0 0 None 0 0 0 0 0
R/Q 20519 Ig-121 41 rs727504191 0.0855 0.059 0.002 N 0.179 0.062 0.149567049428 gnomAD-4.0.0 3.0393E-05 None None None None N None 1.33611E-05 6.01544E-04 None 0 2.23324E-05 None 0 1.64799E-04 5.93636E-06 2.20405E-05 1.60303E-05
R/G 20814 Ig-122 46 None 0.164 None 0.896 N 0.491 0.241 0.465464902746 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
R/G 21218 Ig-123 42 rs778966200 0.4149 -0.09 1.0 N 0.635 0.448 0.524792858863 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
R/G 21218 Ig-123 42 rs778966200 0.4149 -0.09 1.0 N 0.635 0.448 0.524792858863 gnomAD-4.0.0 2.05372E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69916E-06 0 0
T/I 21509 Ig-124 41 None 0.1692 None 0.059 N 0.213 0.19 0.337868961071 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/R 21906 Ig-125 41 rs1193931137 0.1913 None 0.188 N 0.387 0.178 0.395894371353 gnomAD-4.0.0 6.85319E-07 None None None None N None 2.9924E-05 0 None 0 0 None 0 0 0 0 0
D/N 22304 Ig-126 40 None 0.1454 None 0.334 N 0.421 0.198 0.292062946507 gnomAD-4.0.0 1.59281E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86076E-06 0 0
T/S 22593 Ig-127 34 None 0.0887 None 0.349 N 0.401 0.052 0.17948927462 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
N/K 23387 Ig-129 43 None 0.1691 None None N 0.187 0.139 0.119812018005 gnomAD-4.0.0 4.79114E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.30256E-05 0
D/G 24471 Ig-132 41 rs1471781546 0.1191 -0.189 0.892 N 0.478 0.155 0.195762928549 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
D/G 24471 Ig-132 41 rs1471781546 0.1191 -0.189 0.892 N 0.478 0.155 0.195762928549 gnomAD-4.0.0 3.18374E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.8659E-05 0
D/H 24471 Ig-132 41 rs1708675722 0.2299 None 0.995 N 0.481 0.324 0.284150004643 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
Q/E 24758 Ig-133 43 rs1015935551 0.075 None 0.004 N 0.152 0.137 0.212008924253 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
Q/E 24758 Ig-133 43 rs1015935551 0.075 None 0.004 N 0.152 0.137 0.212008924253 gnomAD-4.0.0 6.57592E-06 None None None None N None 0 6.55566E-05 None 0 0 None 0 0 0 0 0
Q/H 24758 Ig-133 43 rs1464894688 0.4235 -0.374 0.939 D 0.269 0.3 0.344483371355 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
Q/H 24758 Ig-133 43 rs1464894688 0.4235 -0.374 0.939 D 0.269 0.3 0.344483371355 gnomAD-4.0.0 6.1588E-06 None None None None N None 0 0 None 0 0 None 0 0 7.1967E-06 0 1.657E-05
N/D 25154 Ig-134 44 None 0.0946 None None N 0.115 0.092 0.209622950755 gnomAD-4.0.0 1.59197E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85959E-06 0 0
D/E 25553 Ig-135 40 rs1453473992 0.0839 0.003 None N 0.147 0.078 0.112648838833 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
D/G 25553 Ig-135 40 rs1197063716 0.1228 -0.391 0.166 D 0.302 0.355 0.233785782151 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.67001E-04
D/G 25553 Ig-135 40 rs1197063716 0.1228 -0.391 0.166 D 0.302 0.355 0.233785782151 gnomAD-4.0.0 3.18749E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43431E-05 3.02847E-05
D/N 25553 Ig-135 40 rs1246439715 0.1017 0.063 0.491 N 0.218 0.211 0.235038932564 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.61E-05 None 0 None 0 0 0
D/N 25553 Ig-135 40 rs1246439715 0.1017 0.063 0.491 N 0.218 0.211 0.235038932564 gnomAD-4.0.0 1.59378E-06 None None None None N None 0 0 None 0 2.78303E-05 None 0 0 0 0 0
D/G 26635 Ig-138 42 rs1301645407 0.1123 None 0.007 N 0.239 0.138 0.101711395817 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/G 26635 Ig-138 42 rs1301645407 0.1123 None 0.007 N 0.239 0.138 0.101711395817 gnomAD-4.0.0 2.56239E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78668E-06 0 0
D/E 27718 Ig-141 43 rs1198738101 0.0858 -0.034 None N 0.207 0.078 0.0138822411134 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 6.54E-05 None 0 0 0
D/E 27718 Ig-141 43 rs1198738101 0.0858 -0.034 None N 0.207 0.078 0.0138822411134 gnomAD-4.0.0 3.4213E-06 None None None None I None 0 0 None 0 0 None 0 0 0 5.79683E-05 0
D/N 27718 Ig-141 43 None 0.1032 None 0.22 N 0.457 0.164 0.119812018005 gnomAD-4.0.0 1.59152E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85848E-06 0 0
E/G 28005 Ig-142 43 None 0.2237 None 0.684 N 0.415 0.396 0.564094393547 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
E/Q 28005 Ig-142 43 rs1451115384 0.1631 0.046 0.012 N 0.179 0.057 0.210429274316 gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.99E-06 0
E/Q 28005 Ig-142 43 rs1451115384 0.1631 0.046 0.012 N 0.179 0.057 0.210429274316 gnomAD-4.0.0 1.59284E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86022E-06 0 0
E/G 28400 Ig-143 43 rs1179703111 0.1099 -0.678 0.003 N 0.199 0.156 0.401753679984 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
E/G 28400 Ig-143 43 rs1179703111 0.1099 -0.678 0.003 N 0.199 0.156 0.401753679984 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
E/G 28400 Ig-143 43 rs1179703111 0.1099 -0.678 0.003 N 0.199 0.156 0.401753679984 gnomAD-4.0.0 1.85904E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69516E-06 0 1.60108E-05
S/N 29882 Ig-147 41 rs755022770 0.0717 0.162 0.351 N 0.203 0.153 None gnomAD-2.1.1 2.42E-05 None None None None N None 0 1.15882E-04 None 0 0 None 0 None 0 1.77E-05 0
S/N 29882 Ig-147 41 rs755022770 0.0717 0.162 0.351 N 0.203 0.153 None gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 6.55E-05 0 0 0 None 0 0 0 0 0
S/N 29882 Ig-147 41 rs755022770 0.0717 0.162 0.351 N 0.203 0.153 None gnomAD-4.0.0 2.10834E-05 None None None None N None 1.33451E-05 6.66733E-05 None 0 2.22777E-05 None 0 3.28839E-04 2.03417E-05 0 3.20256E-05
S/R 29882 Ig-147 41 None 0.289 None 0.351 N 0.409 0.205 0.251639045875 gnomAD-4.0.0 2.40068E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62504E-06 0 0
K/N 30569 Ig-149 38 rs1060500543 0.3369 0.365 0.638 N 0.451 0.21 0.337378238328 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.87E-06 0
K/N 30569 Ig-149 38 rs1060500543 0.3369 0.365 0.638 N 0.451 0.21 0.337378238328 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
K/N 30569 Ig-149 38 rs1060500543 0.3369 0.365 0.638 N 0.451 0.21 0.337378238328 gnomAD-4.0.0 9.2954E-06 None None None None N None 1.33483E-05 0 None 0 0 None 0 0 1.18665E-05 0 0
E/K 31258 Ig-151 41 rs994627256 0.2115 None 0.201 N 0.416 0.277 0.36256342048 gnomAD-4.0.0 1.59112E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85788E-06 0 0
L/I 31658 Ig-152 38 rs754798671 0.0808 -0.111 0.022 N 0.325 0.103 0.167679373172 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
L/I 31658 Ig-152 38 rs754798671 0.0808 -0.111 0.022 N 0.325 0.103 0.167679373172 gnomAD-4.0.0 1.59127E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
S/C 32057 Ig-153 41 None 0.1153 None 0.915 N 0.363 0.509 0.563432924419 gnomAD-4.0.0 1.59141E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85874E-06 0 0
S/G 32057 Ig-153 41 rs766521706 0.0717 -0.039 0.027 N 0.276 0.255 0.303453137403 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 0 0
S/N 32057 Ig-153 41 None 0.0863 None None N 0.149 0.191 0.0611884634855 gnomAD-4.0.0 6.36568E-06 None None None None I None 0 0 None 0 0 None 0 0 1.14351E-05 0 0
Q/E 33143 Ig-156 43 rs1380008073 0.1043 None 0.978 N 0.407 0.379 0.299086750705 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
Q/E 33143 Ig-156 43 rs1380008073 0.1043 None 0.978 N 0.407 0.379 0.299086750705 gnomAD-4.0.0 4.33816E-06 None None None None N None 0 0 None 0 0 None 0 0 4.23814E-06 0 3.20256E-05
Q/K 33143 Ig-156 43 rs1380008073 0.1882 0.316 0.99 N 0.476 0.446 0.314716216878 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
Q/K 33143 Ig-156 43 rs1380008073 0.1882 0.316 0.99 N 0.476 0.446 0.314716216878 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
Q/K 33143 Ig-156 43 rs1380008073 0.1882 0.316 0.99 N 0.476 0.446 0.314716216878 gnomAD-4.0.0 1.23948E-05 None None None None N None 0 0 None 0 0 None 0 0 1.69526E-05 0 0
Q/R 33143 Ig-156 43 None 0.2185 None 0.985 N 0.495 0.319 0.29132392195 gnomAD-4.0.0 1.59139E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8584E-06 0 0
N/S 33638 Ig-159 43 rs760140582 0.1107 0.054 0.864 N 0.372 0.166 0.176091768786 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 1.78E-05 0
N/S 33638 Ig-159 43 rs760140582 0.1107 0.054 0.864 N 0.372 0.166 0.176091768786 gnomAD-4.0.0 9.548E-06 None None None None N None 0 0 None 0 0 None 0 0 1.42924E-05 1.43271E-05 0
P/L 34300 Ig-161 43 rs186977868 0.1221 -0.203 1.0 D 0.723 0.517 None gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 1.67056E-04 None 0 None 0 0 0
P/L 34300 Ig-161 43 rs186977868 0.1221 -0.203 1.0 D 0.723 0.517 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92827E-04 None 0 0 0 0 0
P/L 34300 Ig-161 43 rs186977868 0.1221 -0.203 1.0 D 0.723 0.517 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
P/L 34300 Ig-161 43 rs186977868 0.1221 -0.203 1.0 D 0.723 0.517 None gnomAD-4.0.0 5.12327E-06 None None None None N None 0 0 None 0 9.69885E-05 None 0 0 0 0 0
P/S 34300 Ig-161 43 None 0.1711 None 1.0 N 0.729 0.408 0.35139820857 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/T 34300 Ig-161 43 None 0.1244 None 1.0 N 0.717 0.445 0.560491779295 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/D 34984 Ig-163 43 rs1434654451 0.3543 None 0.434 N 0.246 0.077 0.183819452728 gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
E/D 34984 Ig-163 43 rs1434654451 0.3543 None 0.434 N 0.246 0.077 0.183819452728 gnomAD-4.0.0 8.0552E-06 None None None None N None 1.3349E-05 0 None 0 0 None 0 0 8.47545E-06 0 3.20184E-05
T/I 35171 Ig-164 43 rs774524898 0.1659 -0.299 0.004 N 0.297 0.254 None gnomAD-2.1.1 1.64534E-04 None None None None N None 0 0 None 0 0 None 1.11104E-03 None 0 6.2E-05 0
T/I 35171 Ig-164 43 rs774524898 0.1659 -0.299 0.004 N 0.297 0.254 None gnomAD-3.1.2 7.23E-05 None None None None N None 0 0 0 0 0 None 0 0 7.35E-05 1.24327E-03 0
T/I 35171 Ig-164 43 rs774524898 0.1659 -0.299 0.004 N 0.297 0.254 None gnomAD-4.0.0 1.01619E-04 None None None None N None 0 0 None 0 0 None 0 3.28731E-04 5.00049E-05 1.08691E-03 6.40369E-05
Q/R 35462 Ig-166 43 rs376392819 0.0996 None 0.001 N 0.145 0.201 None gnomAD-3.1.2 3.94E-05 None None None None N None 1.44746E-04 0 0 0 0 None 0 0 0 0 0
Q/R 35462 Ig-166 43 rs376392819 0.0996 None 0.001 N 0.145 0.201 None gnomAD-4.0.0 5.6268E-06 None None None None N None 1.08213E-04 0 None 0 0 None 0 0 8.50044E-07 0 0
N/S 35647 Ig-167 41 None 0.12 None 0.999 N 0.494 0.289 0.362758974969 gnomAD-4.0.0 2.05272E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69845E-06 0 0
I/L 35744 Ig-168 43 rs142336788 0.1049 None None N 0.139 0.074 0.0551355673512 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/L 35744 Ig-168 43 rs142336788 0.1049 None None N 0.139 0.074 0.0551355673512 gnomAD-4.0.0 6.57065E-06 None None None None N None 2.41278E-05 0 None 0 0 None 0 0 0 0 0
I/T 35744 Ig-168 43 None 0.1841 None 0.012 N 0.335 0.321 0.508755544265 gnomAD-4.0.0 6.84708E-07 None None None None N None 0 0 None 0 2.52003E-05 None 0 0 0 0 0
I/V 35744 Ig-168 43 rs142336788 0.0652 0.114 None N 0.159 0.053 None gnomAD-2.1.1 7.91E-05 None None None None N None 6.62471E-04 2.86E-05 None 0 0 None 0 None 0 3.92E-05 0
I/V 35744 Ig-168 43 rs142336788 0.0652 0.114 None N 0.159 0.053 None gnomAD-3.1.2 1.90549E-04 None None None None N None 6.99706E-04 0 0 0 0 None 0 0 0 0 0
I/V 35744 Ig-168 43 rs142336788 0.0652 0.114 None N 0.159 0.053 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
I/V 35744 Ig-168 43 rs142336788 0.0652 0.114 None N 0.159 0.053 None gnomAD-4.0.0 1.04168E-04 None None None None N None 7.20192E-04 1.67235E-05 None 3.38226E-05 2.22896E-05 None 0 0 8.90155E-05 2.20814E-05 6.40594E-05
S/T 35939 Ig-169 43 rs762284215 0.0829 -0.396 None N 0.168 0.069 0.0762999501168 gnomAD-2.1.1 1.07E-05 None None None -1.57(OBSL1) -0.632(OBSCN) N None 0 0 None 0 1.5361E-04 None 0 None 0 0 0
S/T 35939 Ig-169 43 rs762284215 0.0829 -0.396 None N 0.168 0.069 0.0762999501168 gnomAD-3.1.2 1.31E-05 None None None -1.57(OBSL1) -0.632(OBSCN) N None 0 0 0 0 3.84615E-04 None 0 0 0 0 0
S/T 35939 Ig-169 43 rs762284215 0.0829 -0.396 None N 0.168 0.069 0.0762999501168 gnomAD-4.0.0 9.91381E-06 None None None -1.57(OBSL1) -0.632(OBSCN) N None 0 0 None 0 3.34105E-04 None 0 0 0 0 1.60082E-05

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.