Structural position:

  • Domain Type: Ig
  • Aligned Position: 73
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
S/F 49 Ig-1 44 rs368887734 0.3917 -0.913 0.926 D 0.442 0.442 None gnomAD-2.1.1 3.98E-06 None None None 0.177(TCAP) N None 0 0 None 0 0 None 0 None 0 8.8E-06 0
S/F 49 Ig-1 44 rs368887734 0.3917 -0.913 0.926 D 0.442 0.442 None gnomAD-3.1.2 6.57E-06 None None None 0.177(TCAP) N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/F 49 Ig-1 44 rs368887734 0.3917 -0.913 0.926 D 0.442 0.442 None gnomAD-4.0.0 6.57004E-06 None None None 0.177(TCAP) N None 0 0 None 0 0 None 0 0 1.46985E-05 0 0
S/P 49 Ig-1 44 rs531066665 0.5153 -0.478 0.489 D 0.347 0.19 None gnomAD-2.1.1 1.19E-05 None None None 0.001(TCAP) N None 6.15E-05 0 None 0 0 None 0 None 0 1.76E-05 0
S/P 49 Ig-1 44 rs531066665 0.5153 -0.478 0.489 D 0.347 0.19 None gnomAD-3.1.2 6.57E-06 None None None 0.001(TCAP) N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/P 49 Ig-1 44 rs531066665 0.5153 -0.478 0.489 D 0.347 0.19 None 1000 genomes 1.99681E-04 None None None 0.001(TCAP) N None 0 0 None None 0 1E-03 None None None 0 None
S/P 49 Ig-1 44 rs531066665 0.5153 -0.478 0.489 D 0.347 0.19 None gnomAD-4.0.0 3.40742E-05 None None None 0.001(TCAP) N None 3.99808E-05 0 None 0 0 None 0 0 4.40676E-05 0 0
S/Y 49 Ig-1 44 rs368887734 0.3626 None 0.975 D 0.434 0.44 0.616854986462 gnomAD-3.1.2 1.97E-05 None None None 0.422(TCAP) N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
S/Y 49 Ig-1 44 rs368887734 0.3626 None 0.975 D 0.434 0.44 0.616854986462 gnomAD-4.0.0 5.12205E-06 None None None 0.422(TCAP) N None 6.76293E-05 0 None 0 0 None 0 0 0 0 0
S/F 147 Ig-2 44 None 0.8978 None 1.0 D 0.757 0.586 0.860464115049 gnomAD-4.0.0 1.20032E-06 None None None -0.105(TCAP) N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
S/F 986 Ig-3 44 rs755373497 0.98 -1.015 1.0 D 0.77 0.523 0.862337548322 gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/F 986 Ig-3 44 rs755373497 0.98 -1.015 1.0 D 0.77 0.523 0.862337548322 gnomAD-4.0.0 3.18109E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85659E-06 1.43271E-05 0
G/R 1334 Ig-5 44 rs977217136 0.6104 None 0.946 N 0.673 0.276 0.5073929853 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/R 1334 Ig-5 44 rs977217136 0.6104 None 0.946 N 0.673 0.276 0.5073929853 gnomAD-4.0.0 2.5619E-06 None None None None N None 1.69102E-05 1.6952E-05 None 0 0 None 0 0 0 0 0
H/Y 1599 Ig-7 44 rs757510119 0.1674 0.851 0.997 N 0.455 0.425 0.198526703765 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
H/Y 1599 Ig-7 44 rs757510119 0.1674 0.851 0.997 N 0.455 0.425 0.198526703765 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
H/Y 1599 Ig-7 44 rs757510119 0.1674 0.851 0.997 N 0.455 0.425 0.198526703765 gnomAD-4.0.0 2.56127E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78386E-06 0 0
S/N 1884 Ig-9 44 rs749151809 0.8988 -0.181 0.999 N 0.585 0.22 0.137902524267 gnomAD-2.1.1 1.19E-05 None None None None N None 0 0 None 0 0 None 9.8E-05 None 0 0 0
S/N 1884 Ig-9 44 rs749151809 0.8988 -0.181 0.999 N 0.585 0.22 0.137902524267 gnomAD-4.0.0 4.10444E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99303E-07 5.7967E-05 0
S/T 1884 Ig-9 44 rs749151809 0.6474 -0.169 0.999 N 0.479 0.251 0.136095386433 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
S/T 1884 Ig-9 44 rs749151809 0.6474 -0.169 0.999 N 0.479 0.251 0.136095386433 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
S/T 1884 Ig-9 44 rs749151809 0.6474 -0.169 0.999 N 0.479 0.251 0.136095386433 gnomAD-4.0.0 1.85871E-06 None None None None N None 2.66987E-05 0 None 0 0 None 0 0 8.4745E-07 0 0
G/A 2217 Ig-11 44 rs146236689 0.1904 -0.328 0.983 N 0.529 0.254 0.132336055621 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/A 2217 Ig-11 44 rs146236689 0.1904 -0.328 0.983 N 0.529 0.254 0.132336055621 gnomAD-4.0.0 2.05236E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99326E-07 2.31863E-05 0
G/R 2217 Ig-11 44 None 0.3787 None 0.999 N 0.765 0.355 0.410337123052 gnomAD-4.0.0 2.05236E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69797E-06 0 0
N/K 2309 Ig-12 43 rs147580120 0.4188 0.587 0.801 N 0.289 0.109 0.0986583533028 gnomAD-2.1.1 2.39E-05 None None None None N None 3.6914E-04 0 None 0 0 None 0 None 0 0 0
N/K 2309 Ig-12 43 rs147580120 0.4188 0.587 0.801 N 0.289 0.109 0.0986583533028 gnomAD-3.1.2 8.54E-05 None None None None N None 3.13767E-04 0 0 0 0 None 0 0 0 0 0
N/K 2309 Ig-12 43 rs147580120 0.4188 0.587 0.801 N 0.289 0.109 0.0986583533028 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
N/K 2309 Ig-12 43 rs147580120 0.4188 0.587 0.801 N 0.289 0.109 0.0986583533028 gnomAD-4.0.0 1.17714E-05 None None None None N None 2.3991E-04 0 None 0 0 None 0 0 0 0 1.59974E-05
N/S 2309 Ig-12 43 rs1405410487 0.0613 0.351 0.007 N 0.125 0.109 0.0806252709748 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 5.44E-05 None 0 None 0 0 0
N/S 2309 Ig-12 43 rs1405410487 0.0613 0.351 0.007 N 0.125 0.109 0.0806252709748 gnomAD-4.0.0 1.59055E-06 None None None None N None 0 0 None 0 2.77254E-05 None 0 0 0 0 0
S/I 2398 Ig-13 43 rs766170235 0.3951 0.174 0.667 D 0.529 0.366 0.584767571859 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.82E-06 0
S/I 2398 Ig-13 43 rs766170235 0.3951 0.174 0.667 D 0.529 0.366 0.584767571859 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/I 2398 Ig-13 43 rs766170235 0.3951 0.174 0.667 D 0.529 0.366 0.584767571859 gnomAD-4.0.0 3.84197E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17552E-06 0 0
D/H 2488 Ig-14 44 rs928988828 0.487 None 1.0 D 0.388 0.279 0.276482976112 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
D/H 2488 Ig-14 44 rs928988828 0.487 None 1.0 D 0.388 0.279 0.276482976112 gnomAD-4.0.0 2.02985E-06 None None None None N None 3.49504E-05 0 None 0 0 None 0 0 0 0 0
D/V 2488 Ig-14 44 None 0.4246 None 0.994 D 0.527 0.416 0.40146981186 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/C 2575 Ig-15 43 rs1469009599 0.1743 -0.387 0.78 N 0.336 0.185 0.282575091529 gnomAD-2.1.1 3.18E-05 None None None None N None 0 0 None 0 6.42674E-04 None 0 None 0 0 0
S/C 2575 Ig-15 43 rs1469009599 0.1743 -0.387 0.78 N 0.336 0.185 0.282575091529 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92604E-04 None 0 0 0 0 0
S/C 2575 Ig-15 43 rs1469009599 0.1743 -0.387 0.78 N 0.336 0.185 0.282575091529 gnomAD-4.0.0 6.57117E-06 None None None None N None 0 0 None 0 1.92604E-04 None 0 0 0 0 0
S/G 2575 Ig-15 43 None 0.0806 None None N 0.129 0.093 0.104622674875 gnomAD-4.0.0 1.591E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85695E-06 0 0
N/I 2750 Ig-17 44 rs1471538206 0.3233 -0.024 0.317 D 0.471 0.248 0.437314048365 gnomAD-2.1.1 3.98E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
N/I 2750 Ig-17 44 rs1471538206 0.3233 -0.024 0.317 D 0.471 0.248 0.437314048365 gnomAD-4.0.0 3.42032E-06 None None None None N None 0 4.47207E-05 None 0 0 None 0 0 2.69788E-06 0 0
N/S 2750 Ig-17 44 rs1471538206 0.0568 -0.148 None N 0.154 0.06 0.126345400529 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.82E-06 0
N/S 2750 Ig-17 44 rs1471538206 0.0568 -0.148 None N 0.154 0.06 0.126345400529 gnomAD-3.1.2 6.57E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
N/S 2750 Ig-17 44 rs1471538206 0.0568 -0.148 None N 0.154 0.06 0.126345400529 gnomAD-4.0.0 5.57615E-06 None None None None N None 0 1.66689E-05 None 0 1.11408E-04 None 0 0 2.54237E-06 0 0
S/C 2837 Ig-18 43 rs202024134 0.2051 -0.275 1.0 D 0.435 0.473 None gnomAD-2.1.1 4.78E-05 None None None None N None 0 0 None 0 0 None 0 None 9.24E-05 8.8E-05 0
S/C 2837 Ig-18 43 rs202024134 0.2051 -0.275 1.0 D 0.435 0.473 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 9.41E-05 0 2.94E-05 0 0
S/C 2837 Ig-18 43 rs202024134 0.2051 -0.275 1.0 D 0.435 0.473 None gnomAD-4.0.0 4.22571E-05 None None None None N None 0 0 None 0 0 None 1.56828E-04 0 5.26175E-05 0 2.84172E-05
S/G 2837 Ig-18 43 rs202024134 0.0936 -0.522 0.135 N 0.186 0.172 0.124217242631 gnomAD-2.1.1 3.98E-06 None None None None N None 0 2.89E-05 None 0 0 None 0 None 0 0 0
S/G 2837 Ig-18 43 rs202024134 0.0936 -0.522 0.135 N 0.186 0.172 0.124217242631 gnomAD-4.0.0 3.18094E-06 None None None None N None 0 4.57268E-05 None 0 0 None 0 0 0 0 0
S/R 2837 Ig-18 43 rs1166608062 0.9449 None 0.997 D 0.35 0.452 0.277317399466 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/R 2837 Ig-18 43 rs1166608062 0.9449 None 0.997 D 0.35 0.452 0.277317399466 gnomAD-4.0.0 6.19566E-06 None None None None N None 0 0 None 0 0 None 0 0 8.4744E-06 0 0
S/N 2924 Ig-19 43 rs745523949 0.5186 -0.033 0.994 D 0.435 0.36 0.39162414616 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
S/N 2924 Ig-19 43 rs745523949 0.5186 -0.033 0.994 D 0.435 0.36 0.39162414616 gnomAD-4.0.0 1.16291E-05 None None None None N None 0 0 None 0 2.51902E-05 None 0 0 1.43887E-05 0 0
S/R 2924 Ig-19 43 rs778525693 0.9881 0.036 0.998 D 0.535 0.693 0.483816155017 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
S/R 2924 Ig-19 43 rs778525693 0.9881 0.036 0.998 D 0.535 0.693 0.483816155017 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/R 2924 Ig-19 43 rs778525693 0.9881 0.036 0.998 D 0.535 0.693 0.483816155017 gnomAD-4.0.0 1.59049E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85652E-06 0 0
S/T 2924 Ig-19 43 rs745523949 0.2808 None 0.543 D 0.267 0.378 0.28297238246 gnomAD-4.0.0 6.84062E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99295E-07 0 0
T/I 3011 Ig-20 43 rs753265092 0.8269 -0.079 0.994 N 0.412 0.391 0.267299060538 gnomAD-2.1.1 7.96E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.76E-05 0
T/I 3011 Ig-20 43 rs753265092 0.8269 -0.079 0.994 N 0.412 0.391 0.267299060538 gnomAD-4.0.0 3.18122E-06 None None None None N None 0 0 None 0 0 None 0 0 5.71298E-06 0 0
T/I 3100 Ig-21 43 rs780950679 0.1303 0.089 None N 0.203 0.039 0.0401082797425 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
T/I 3100 Ig-21 43 rs780950679 0.1303 0.089 None N 0.203 0.039 0.0401082797425 gnomAD-4.0.0 3.1811E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85651E-06 1.43271E-05 0
Q/E 3191 Ig-22 45 rs33997263 0.055 -0.627 None N 0.086 0.092 None gnomAD-2.1.1 8.5E-05 None None None None N None 0 0 None 0 1.10464E-03 None 6.53E-05 None 0 0 0
Q/E 3191 Ig-22 45 rs33997263 0.055 -0.627 None N 0.086 0.092 None gnomAD-3.1.2 8.54E-05 None None None None N None 0 0 0 0 2.31214E-03 None 0 0 0 2.07641E-04 0
Q/E 3191 Ig-22 45 rs33997263 0.055 -0.627 None N 0.086 0.092 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
Q/E 3191 Ig-22 45 rs33997263 0.055 -0.627 None N 0.086 0.092 None gnomAD-4.0.0 2.72603E-05 None None None None N None 0 0 None 0 7.80309E-04 None 0 0 0 4.39223E-05 7.99923E-05
T/A 3508 Ig-25 44 None 0.0911 None None None None 0.101 None gnomAD-4.0.0 3.42092E-06 None None None None I None 0 0 None 0 0 None 0 0 3.59779E-06 0 1.65645E-05
T/I 3508 Ig-25 44 rs397517823 0.4262 None None None None 0.147 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07039E-04 0
T/I 3508 Ig-25 44 rs397517823 0.4262 None None None None 0.147 None gnomAD-4.0.0 9.29552E-06 None None None None I None 6.67646E-05 0 None 0 0 None 0 0 3.39043E-06 6.58733E-05 0
T/K 3508 Ig-25 44 rs397517823 0.1908 -0.197 None None None 0.131 None gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
T/K 3508 Ig-25 44 rs397517823 0.1908 -0.197 None None None 0.131 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
T/K 3508 Ig-25 44 rs397517823 0.1908 -0.197 None None None 0.131 None gnomAD-4.0.0 6.57402E-06 None None None None I None 0 0 None 0 0 None 0 0 1.4702E-05 0 0
T/P 3508 Ig-25 44 None 0.2778 None None None None 0.078 None gnomAD-4.0.0 1.36837E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79889E-06 0 0
T/R 3508 Ig-25 44 None 0.1373 None None None None 0.135 None gnomAD-4.0.0 6.84198E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99463E-07 0 0
S/F 3703 Ig-26 44 rs773438970 0.3324 None None None None 0.117 None gnomAD-4.0.0 6.84195E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65645E-05
S/Y 3703 Ig-26 44 rs773438970 0.2555 -0.519 None None None 0.114 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
S/Y 3703 Ig-26 44 rs773438970 0.2555 -0.519 None None None 0.114 None gnomAD-4.0.0 1.36839E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79888E-06 0 0
S/F 3863 Ig-27 44 None 0.4666 None 0.997 D 0.595 0.414 None gnomAD-4.0.0 6.84196E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9946E-07 0 0
S/Y 3863 Ig-27 44 None 0.447 None 0.997 D 0.581 0.414 None gnomAD-4.0.0 6.84196E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.15931E-05 0
S/T 3981 Ig-28 44 rs761366397 0.124 0.017 0.027 N 0.373 0.102 0.0401082797425 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/T 3981 Ig-28 44 rs761366397 0.124 0.017 0.027 N 0.373 0.102 0.0401082797425 gnomAD-4.0.0 3.18219E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85789E-06 1.43271E-05 0
D/G 4647 Ig-29 42 rs781348816 0.1068 -0.588 None N 0.199 0.129 None gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.91E-05 0
D/G 4647 Ig-29 42 rs781348816 0.1068 -0.588 None N 0.199 0.129 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/G 4647 Ig-29 42 rs781348816 0.1068 -0.588 None N 0.199 0.129 None gnomAD-4.0.0 1.17786E-05 None None None None I None 1.33447E-04 0 None 0 0 None 0 3.29164E-04 5.9352E-06 0 0
D/N 4647 Ig-29 42 rs2082068479 0.0829 None 0.324 N 0.298 0.135 None gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
D/N 4647 Ig-29 42 rs2082068479 0.0829 None 0.324 N 0.298 0.135 None gnomAD-4.0.0 1.23994E-06 None None None None I None 1.33515E-05 0 None 0 0 None 0 0 8.47919E-07 0 0
S/N 4743 Ig-30 44 None 0.2982 None 0.549 N 0.391 0.153 0.149567049428 gnomAD-4.0.0 1.5917E-06 None None None None N None 5.65419E-05 0 None 0 0 None 0 0 0 0 0
S/R 4743 Ig-30 44 None 0.9626 None 0.81 D 0.327 0.253 0.227934060464 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/L 4838 Ig-31 44 rs758347900 0.0976 0.017 0.002 D 0.205 0.198 0.366277470483 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
S/L 4838 Ig-31 44 rs758347900 0.0976 0.017 0.002 D 0.205 0.198 0.366277470483 gnomAD-4.0.0 4.77339E-06 None None None None I None 0 0 None 0 0 None 0 0 8.57412E-06 0 0
G/R 4931 Ig-32 44 rs767070682 0.3227 -0.315 0.901 N 0.466 0.281 0.443695250439 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 9.3E-05 0 0
G/R 4931 Ig-32 44 rs767070682 0.3227 -0.315 0.901 N 0.466 0.281 0.443695250439 gnomAD-4.0.0 3.18289E-06 None None None None N None 0 0 None 0 0 None 3.7679E-05 0 0 0 0
S/G 5118 Ig-34 44 rs747924639 0.1329 -0.524 0.91 N 0.407 0.283 0.281780670237 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/G 5118 Ig-34 44 rs747924639 0.1329 -0.524 0.91 N 0.407 0.283 0.281780670237 gnomAD-4.0.0 1.36847E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.31922E-05 0
S/R 5118 Ig-34 44 rs747924639 0.9844 0.109 0.994 D 0.377 0.606 0.515603885326 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
S/R 5118 Ig-34 44 rs747924639 0.9844 0.109 0.994 D 0.377 0.606 0.515603885326 gnomAD-4.0.0 6.84234E-06 None None None None N None 0 0 None 0 0 None 0 1.7343E-04 4.49746E-06 4.63843E-05 0
S/T 5118 Ig-34 44 rs781058314 0.1904 0.017 0.98 D 0.423 0.316 0.346768085243 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
S/T 5118 Ig-34 44 rs781058314 0.1904 0.017 0.98 D 0.423 0.316 0.346768085243 gnomAD-4.0.0 1.59161E-06 None None None None N None 0 0 None 0 2.775E-05 None 0 0 0 0 0
D/A 5211 Ig-35 44 rs1174909402 0.1658 -0.423 0.865 N 0.485 0.142 0.301455362545 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
D/A 5211 Ig-35 44 rs1174909402 0.1658 -0.423 0.865 N 0.485 0.142 0.301455362545 gnomAD-4.0.0 1.59118E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
D/E 5211 Ig-35 44 rs534365478 0.1923 -0.257 0.985 N 0.397 0.193 0.163833314356 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
D/E 5211 Ig-35 44 rs534365478 0.1923 -0.257 0.985 N 0.397 0.193 0.163833314356 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/E 5211 Ig-35 44 rs534365478 0.1923 -0.257 0.985 N 0.397 0.193 0.163833314356 gnomAD-4.0.0 6.57557E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47029E-05 0 0
D/H 5211 Ig-35 44 None 0.289 None 0.999 N 0.615 0.335 0.220303561663 gnomAD-4.0.0 2.05257E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99468E-07 2.31868E-05 0
D/N 5211 Ig-35 44 None 0.0813 None 0.978 N 0.533 0.22 0.194818534648 gnomAD-4.0.0 6.84191E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99468E-07 0 0
S/G 5304 Ig-36 44 None 0.1037 None 0.002 N 0.15 0.158 0.0846915920261 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/N 5304 Ig-36 44 rs1560825296 0.3035 None 0.012 N 0.243 0.132 0.104622674875 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
S/N 5304 Ig-36 44 rs1560825296 0.3035 None 0.012 N 0.243 0.132 0.104622674875 gnomAD-4.0.0 1.36843E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79896E-06 0 0
S/T 5304 Ig-36 44 None 0.1472 None 0.801 N 0.411 0.18 0.148003135375 gnomAD-4.0.0 6.84214E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99478E-07 0 0
S/F 5400 Ig-37 44 None 0.4092 None 0.317 N 0.376 0.233 0.382592752248 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
S/P 5400 Ig-37 44 None 0.6094 None 0.484 N 0.347 0.123 0.28492961333 gnomAD-4.0.0 1.59169E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85855E-06 0 0
G/D 5493 Ig-38 44 rs1418252439 0.2212 -0.068 1.0 N 0.655 0.418 0.19670166235 gnomAD-2.1.1 4.03E-06 None None None None I None 6.47E-05 0 None 0 0 None 0 None 0 0 0
G/D 5493 Ig-38 44 rs1418252439 0.2212 -0.068 1.0 N 0.655 0.418 0.19670166235 gnomAD-3.1.2 1.97E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 2.07469E-04 0
G/D 5493 Ig-38 44 rs1418252439 0.2212 -0.068 1.0 N 0.655 0.418 0.19670166235 gnomAD-4.0.0 4.06003E-06 None None None None I None 3.49601E-05 0 None 0 0 None 0 0 0 9.3985E-05 0
G/S 5493 Ig-38 44 rs377042940 0.1001 -0.345 1.0 N 0.667 0.288 None gnomAD-2.1.1 1.03706E-04 None None None None I None 1.19973E-03 0 None 0 0 None 0 None 0 0 0
G/S 5493 Ig-38 44 rs377042940 0.1001 -0.345 1.0 N 0.667 0.288 None gnomAD-3.1.2 2.36777E-04 None None None None I None 8.69607E-04 0 0 0 0 None 0 0 0 0 0
G/S 5493 Ig-38 44 rs377042940 0.1001 -0.345 1.0 N 0.667 0.288 None 1000 genomes 3.99361E-04 None None None None I None 1.5E-03 0 None None 0 0 None None None 0 None
G/S 5493 Ig-38 44 rs377042940 0.1001 -0.345 1.0 N 0.667 0.288 None gnomAD-4.0.0 4.27613E-05 None None None None I None 9.06739E-04 0 None 0 0 None 0 0 0 0 1.60072E-05
S/G 5587 Ig-39 45 rs2080667352 0.0731 None None N 0.185 0.091 0.0806252709748 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/D 5680 Ig-40 44 None 0.5256 None 0.012 N 0.305 0.242 0.107399877778 gnomAD-4.0.0 6.84208E-07 None None None None I None 2.98775E-05 0 None 0 0 None 0 0 0 0 0
G/R 5680 Ig-40 44 rs769986653 0.574 -0.051 0.934 N 0.413 0.275 0.478680857624 gnomAD-2.1.1 1.61E-05 None None None None I None 0 1.15908E-04 None 0 0 None 0 None 0 0 0
G/R 5680 Ig-40 44 rs769986653 0.574 -0.051 0.934 N 0.413 0.275 0.478680857624 gnomAD-4.0.0 3.42107E-06 None None None None I None 0 1.11817E-04 None 0 0 None 0 0 0 0 0
G/S 5680 Ig-40 44 rs769986653 0.0756 None 0.051 N 0.236 0.094 0.0762999501168 gnomAD-4.0.0 3.42107E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49744E-06 0 0
G/V 5680 Ig-40 44 None 0.2843 None 0.669 N 0.409 0.278 0.547384771329 gnomAD-4.0.0 6.84208E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99488E-07 0 0
D/E 5773 Ig-41 44 rs760724229 0.2601 0.12 0.967 N 0.397 0.14 0.132336055621 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
G/C 5866 Ig-42 44 rs753136638 0.2152 -0.619 0.999 N 0.758 0.42 0.548443230319 gnomAD-2.1.1 8.03E-05 None None None None N None 0 4.63768E-04 None 0 0 None 0 None 0 1.77E-05 3.30688E-04
G/C 5866 Ig-42 44 rs753136638 0.2152 -0.619 0.999 N 0.758 0.42 0.548443230319 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.31148E-04 0 0 0 None 0 0 1.47E-05 0 0
G/C 5866 Ig-42 44 rs753136638 0.2152 -0.619 0.999 N 0.758 0.42 0.548443230319 gnomAD-4.0.0 1.73544E-05 None None None None N None 4.00919E-05 3.0019E-04 None 0 0 None 0 0 5.93371E-06 0 0
S/G 5962 Ig-43 44 None 0.087 None 0.001 N 0.135 0.06 0.110078149338 gnomAD-4.0.0 2.05278E-06 None None None None N None 0 0 None 0 0 None 0 0 2.6986E-06 0 0
S/I 5962 Ig-43 44 None 0.6101 None 0.963 N 0.375 0.399 0.405839309607 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.21507E-04 0
G/E 6055 Ig-44 44 rs879034244 0.4657 None 0.669 N 0.373 0.246 0.407357902709 gnomAD-4.0.0 2.7375E-06 None None None None N None 0 2.23944E-05 None 0 0 None 0 0 1.79915E-06 0 1.65728E-05
I/V 6149 Ig-45 45 rs368897297 0.0657 -0.311 None N 0.118 0.121 None gnomAD-2.1.1 1.43E-05 None None None None N None 0 0 None 0 5.13E-05 None 0 None 0 2.34E-05 0
I/V 6149 Ig-45 45 rs368897297 0.0657 -0.311 None N 0.118 0.121 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 2.06868E-04 0
I/V 6149 Ig-45 45 rs368897297 0.0657 -0.311 None N 0.118 0.121 None gnomAD-4.0.0 3.03638E-05 None None None None N None 0 0 None 0 2.23005E-05 None 0 0 3.98394E-05 1.09786E-05 0
S/G 6242 Ig-46 44 None 0.0609 None 0.001 N 0.237 0.106 0.0806252709748 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
D/G 6335 Ig-47 44 rs72648951 0.0907 0.386 0.001 N 0.301 0.104 None gnomAD-2.1.1 3.03735E-03 None None None None I None 3.22379E-02 1.33819E-03 None 0 0 None 6.57E-05 None 0 7.11E-05 1.56383E-03
D/G 6335 Ig-47 44 rs72648951 0.0907 0.386 0.001 N 0.301 0.104 None gnomAD-3.1.2 9.37455E-03 None None None None I None 3.2413E-02 3.53774E-03 0 0 0 None 0 3.16456E-03 5.88E-05 2.06782E-04 1.09838E-02
D/G 6335 Ig-47 44 rs72648951 0.0907 0.386 0.001 N 0.301 0.104 None 1000 genomes 9.1853E-03 None None None None I None 3.25E-02 4.3E-03 None None 0 0 None None None 0 None
D/G 6335 Ig-47 44 rs72648951 0.0907 0.386 0.001 N 0.301 0.104 None gnomAD-4.0.0 1.66469E-03 None None None None I None 3.14917E-02 2.15481E-03 None 0 0 None 0 4.95704E-04 2.79797E-05 6.59413E-05 2.4348E-03
D/N 6335 Ig-47 44 rs1346291126 0.0767 0.708 0.002 N 0.217 0.072 0.126345400529 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.99E-06 0
D/N 6335 Ig-47 44 rs1346291126 0.0767 0.708 0.002 N 0.217 0.072 0.126345400529 gnomAD-4.0.0 1.36926E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79948E-06 0 0
D/V 6335 Ig-47 44 None 0.2098 None 0.497 N 0.517 0.214 0.471292358255 gnomAD-4.0.0 1.36923E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79947E-06 0 0
S/C 6428 Ig-48 44 rs727505137 0.4006 None 1.0 N 0.424 0.448 0.370240404367 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06868E-04 0
S/C 6428 Ig-48 44 rs727505137 0.4006 None 1.0 N 0.424 0.448 0.370240404367 gnomAD-4.0.0 6.40932E-06 None None None None N None 0 0 None 0 4.85861E-05 None 0 0 0 2.68039E-05 2.84835E-05
S/I 6428 Ig-48 44 rs748391553 0.8694 0.169 0.4 N 0.314 0.266 0.479893544335 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
S/I 6428 Ig-48 44 rs748391553 0.8694 0.169 0.4 N 0.314 0.266 0.479893544335 gnomAD-4.0.0 1.59246E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85972E-06 0 0
S/T 6428 Ig-48 44 None 0.2422 None 0.99 N 0.423 0.233 0.141422826196 gnomAD-4.0.0 1.59246E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
G/D 6617 Ig-50 44 rs371847228 0.3446 0.166 1.0 N 0.684 0.43 None gnomAD-2.1.1 6.78E-05 None None None None N None 6.20347E-04 8.49E-05 None 0 0 None 0 None 0 0 1.40449E-04
G/D 6617 Ig-50 44 rs371847228 0.3446 0.166 1.0 N 0.684 0.43 None gnomAD-3.1.2 2.17025E-04 None None None None N None 7.48395E-04 6.56E-05 0 0 0 None 0 0 1.47E-05 0 0
G/D 6617 Ig-50 44 rs371847228 0.3446 0.166 1.0 N 0.684 0.43 None gnomAD-4.0.0 3.53334E-05 None None None None N None 6.54608E-04 8.33722E-05 None 0 0 None 0 0 8.47836E-07 0 3.20318E-05
S/G 6898 Ig-53 45 rs878854291 0.1136 None 0.005 N 0.119 0.098 0.0806252709748 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
S/G 6898 Ig-53 45 rs878854291 0.1136 None 0.005 N 0.119 0.098 0.0806252709748 gnomAD-4.0.0 8.05822E-06 None None None None N None 0 0 None 0 0 None 0 0 1.01736E-05 0 1.60149E-05
S/R 6898 Ig-53 45 rs878854291 0.8253 None 0.988 N 0.318 0.282 0.281780670237 gnomAD-4.0.0 1.59237E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86026E-06 0 0
S/I 6991 Ig-54 44 rs373585016 0.3803 0.119 0.966 N 0.388 0.375 0.500426043041 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/I 6991 Ig-54 44 rs373585016 0.3803 0.119 0.966 N 0.388 0.375 0.500426043041 gnomAD-4.0.0 2.7373E-06 None None None None I None 0 0 None 0 5.04032E-05 None 0 0 8.99599E-07 1.15947E-05 0
S/N 6991 Ig-54 44 rs373585016 0.1341 0.126 0.012 N 0.309 0.155 None gnomAD-2.1.1 8.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
S/N 6991 Ig-54 44 rs373585016 0.1341 0.126 0.012 N 0.309 0.155 None gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/N 6991 Ig-54 44 rs373585016 0.1341 0.126 0.012 N 0.309 0.155 None gnomAD-4.0.0 1.05364E-05 None None None None I None 0 0 None 0 0 None 0 0 1.27161E-05 0 3.20307E-05
S/R 6991 Ig-54 44 rs778559152 0.7189 0.1 0.934 N 0.311 0.235 0.241078983079 gnomAD-2.1.1 2.14E-05 None None None None I None 0 2.83E-05 None 0 0 None 0 None 0 3.13E-05 1.40687E-04
S/R 6991 Ig-54 44 rs778559152 0.7189 0.1 0.934 N 0.311 0.235 0.241078983079 gnomAD-3.1.2 1.97E-05 None None None None I None 0 6.56E-05 0 0 0 None 0 0 2.94E-05 0 0
S/R 6991 Ig-54 44 rs778559152 0.7189 0.1 0.934 N 0.311 0.235 0.241078983079 gnomAD-4.0.0 1.02529E-05 None None None None I None 0 3.39179E-05 None 0 0 None 0 0 1.43647E-05 0 0
G/R 7087 Ig-55 44 rs1170087818 0.351 -0.078 0.999 N 0.747 0.385 0.615496883321 gnomAD-2.1.1 8.06E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 4.64E-05 0 0
G/R 7087 Ig-55 44 rs1170087818 0.351 -0.078 0.999 N 0.747 0.385 0.615496883321 gnomAD-4.0.0 3.1838E-06 None None None None I None 0 0 None 0 0 None 1.8826E-05 0 0 1.43295E-05 0
G/R 7180 Ig-56 44 rs760549917 0.4509 -0.33 0.595 N 0.413 0.34 0.395289904662 gnomAD-2.1.1 3.62E-05 None None None None N None 0 0 None 0 0 None 0 None 0 8E-05 0
G/R 7180 Ig-56 44 rs760549917 0.4509 -0.33 0.595 N 0.413 0.34 0.395289904662 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
G/R 7180 Ig-56 44 rs760549917 0.4509 -0.33 0.595 N 0.413 0.34 0.395289904662 gnomAD-4.0.0 1.85951E-05 None None None None N None 0 0 None 0 0 None 1.56299E-05 0 2.45845E-05 0 0
S/F 7273 Ig-57 44 rs768091794 0.4606 -0.981 0.999 N 0.693 0.342 0.606518698375 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.59E-05 None 0 None 0 0 0
S/F 7273 Ig-57 44 rs768091794 0.4606 -0.981 0.999 N 0.693 0.342 0.606518698375 gnomAD-4.0.0 6.36791E-06 None None None None N None 0 0 None 0 1.10994E-04 None 0 0 0 0 0
T/S 7366 Ig-58 44 None 0.0844 None 0.159 N 0.187 0.062 0.0611884634855 gnomAD-4.0.0 1.36875E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99603E-07 0 1.65788E-05
D/E 7462 Ig-59 44 rs183482849 0.2157 0.025 0.994 D 0.421 0.329 0.285698343383 gnomAD-2.1.1 1.18103E-04 None None None None I None 0 1.13295E-04 None 0 0 None 0 None 0 2.27565E-04 0
D/E 7462 Ig-59 44 rs183482849 0.2157 0.025 0.994 D 0.421 0.329 0.285698343383 gnomAD-3.1.2 4.6E-05 None None None None I None 0 6.56E-05 0 0 0 None 0 0 8.82E-05 0 0
D/E 7462 Ig-59 44 rs183482849 0.2157 0.025 0.994 D 0.421 0.329 0.285698343383 1000 genomes 1.99681E-04 None None None None I None 0 1.4E-03 None None 0 0 None None None 0 None
D/E 7462 Ig-59 44 rs183482849 0.2157 0.025 0.994 D 0.421 0.329 0.285698343383 gnomAD-4.0.0 1.3687E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79926E-06 0 0
D/G 7462 Ig-59 44 rs750133852 0.1287 0.212 0.999 N 0.587 0.301 0.348101942276 gnomAD-2.1.1 1.79E-05 None None None None I None 2.06817E-04 0 None 0 0 None 0 None 0 0 0
D/G 7462 Ig-59 44 rs750133852 0.1287 0.212 0.999 N 0.587 0.301 0.348101942276 gnomAD-3.1.2 5.92E-05 None None None None I None 2.17108E-04 0 0 0 0 None 0 0 0 0 0
D/G 7462 Ig-59 44 rs750133852 0.1287 0.212 0.999 N 0.587 0.301 0.348101942276 gnomAD-4.0.0 1.0537E-05 None None None None I None 1.73565E-04 1.66783E-05 None 0 2.22985E-05 None 0 0 0 1.09815E-05 1.60154E-05
D/H 7462 Ig-59 44 rs12693166 0.2703 0.559 1.0 N 0.683 0.532 None gnomAD-2.1.1 1.76716E-01 None None None None I None 1.70641E-01 1.74297E-01 None 1.22599E-01 4.30641E-01 None 2.22364E-01 None 9.448E-02 1.50119E-01 1.61877E-01
D/H 7462 Ig-59 44 rs12693166 0.2703 0.559 1.0 N 0.683 0.532 None gnomAD-3.1.2 1.70045E-01 None None None None I None 1.71672E-01 1.72923E-01 4.75664E-01 1.26009E-01 4.34149E-01 None 9.82615E-02 1.20253E-01 1.5413E-01 2.25083E-01 1.68744E-01
D/H 7462 Ig-59 44 rs12693166 0.2703 0.559 1.0 N 0.683 0.532 None 1000 genomes 2.47005E-01 None None None None I None 2.02E-01 1.844E-01 None None 4.375E-01 1.581E-01 None None None 2.474E-01 None
D/H 7462 Ig-59 44 rs12693166 0.2703 0.559 1.0 N 0.683 0.532 None gnomAD-4.0.0 1.64438E-01 None None None None I None 1.71917E-01 1.74628E-01 None 1.24223E-01 4.42954E-01 None 9.43334E-02 1.95343E-01 1.52596E-01 2.20228E-01 1.71519E-01
D/N 7462 Ig-59 44 rs12693166 0.0897 0.666 1.0 N 0.683 0.356 0.45755974854 gnomAD-2.1.1 2.82E-05 None None None None I None 0 2.91E-05 None 0 3.34747E-04 None 0 None 0 0 0
D/N 7462 Ig-59 44 rs12693166 0.0897 0.666 1.0 N 0.683 0.356 0.45755974854 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 1.9425E-04 None 0 0 0 0 0
D/N 7462 Ig-59 44 rs12693166 0.0897 0.666 1.0 N 0.683 0.356 0.45755974854 gnomAD-4.0.0 3.71935E-06 None None None None I None 0 1.66828E-05 None 0 6.69523E-05 None 0 0 1.69565E-06 0 0
G/R 7558 Ig-60 44 None 0.8192 None 1.0 N 0.711 0.404 0.409665357357 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/V 7558 Ig-60 44 rs886055294 0.7516 -0.388 1.0 N 0.732 0.422 0.478527412683 gnomAD-2.1.1 8.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.77E-05 0
G/V 7558 Ig-60 44 rs886055294 0.7516 -0.388 1.0 N 0.732 0.422 0.478527412683 gnomAD-4.0.0 2.73727E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59843E-06 0 0
S/R 7839 Ig-63 45 None 0.7915 None None N 0.233 0.252 0.166414681773 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/E 7932 Ig-64 44 rs1271514661 0.2005 None 0.117 N 0.262 0.05 0.107399877778 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/E 7932 Ig-64 44 rs1271514661 0.2005 None 0.117 N 0.262 0.05 0.107399877778 gnomAD-4.0.0 6.57428E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47024E-05 0 0
D/G 7932 Ig-64 44 None 0.0867 None None N 0.19 0.116 0.0666544352282 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
G/A 8028 Ig-65 44 rs560897705 0.1232 -0.12 0.41 N 0.369 0.286 0.194818534648 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.49E-05 0
G/A 8028 Ig-65 44 rs560897705 0.1232 -0.12 0.41 N 0.369 0.286 0.194818534648 gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 0 0 None 0 0 4.41E-05 0 0
G/A 8028 Ig-65 44 rs560897705 0.1232 -0.12 0.41 N 0.369 0.286 0.194818534648 gnomAD-4.0.0 6.19751E-06 None None None None I None 0 0 None 0 0 None 0 0 8.47644E-06 0 0
G/A 8121 Ig-66 44 rs1394976705 0.1526 0.058 0.955 N 0.477 0.263 0.148003135375 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 4.64E-05 0 0
G/A 8121 Ig-66 44 rs1394976705 0.1526 0.058 0.955 N 0.477 0.263 0.148003135375 gnomAD-4.0.0 6.84222E-07 None None None None N None 0 0 None 0 0 None 1.87301E-05 0 0 0 0
G/E 8121 Ig-66 44 None 0.1888 None 0.987 N 0.624 0.31 0.327686398923 gnomAD-4.0.0 6.84222E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99486E-07 0 0
G/R 8121 Ig-66 44 rs778894201 0.2039 -0.021 0.997 N 0.723 0.392 0.512707719942 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/R 8121 Ig-66 44 rs778894201 0.2039 -0.021 0.997 N 0.723 0.392 0.512707719942 gnomAD-4.0.0 1.59133E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
A/G 8307 Ig-68 44 rs2077769834 0.1604 None None N 0.106 0.216 0.295974979623 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
D/G 8403 Ig-69 44 rs758110981 0.1809 0.358 0.001 N 0.173 0.145 0.0611884634855 gnomAD-2.1.1 8.07E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
D/G 8403 Ig-69 44 rs758110981 0.1809 0.358 0.001 N 0.173 0.145 0.0611884634855 gnomAD-4.0.0 2.73746E-06 None None None None I None 0 0 None 0 0 None 0 0 3.59841E-06 0 0
D/V 8403 Ig-69 44 None 0.3643 None 0.283 N 0.348 0.174 0.326074293725 gnomAD-4.0.0 6.84364E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99603E-07 0 0
D/Y 8403 Ig-69 44 rs779553584 0.3658 0.119 0.99 N 0.29 0.248 0.38242337071 gnomAD-2.1.1 8.07E-06 None None None None I None 0 0 None 0 0 None 6.55E-05 None 0 0 0
D/Y 8403 Ig-69 44 rs779553584 0.3658 0.119 0.99 N 0.29 0.248 0.38242337071 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
D/Y 8403 Ig-69 44 rs779553584 0.3658 0.119 0.99 N 0.29 0.248 0.38242337071 gnomAD-4.0.0 5.12681E-06 None None None None I None 3.38318E-05 0 None 0 0 None 0 0 0 2.6824E-05 0
S/R 8593 Ig-71 45 rs560562125 0.7274 -0.086 0.92 N 0.329 0.257 0.260735089382 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
S/R 8593 Ig-71 45 rs560562125 0.7274 -0.086 0.92 N 0.329 0.257 0.260735089382 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.08247E-04 0
S/R 8593 Ig-71 45 rs560562125 0.7274 -0.086 0.92 N 0.329 0.257 0.260735089382 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
S/R 8593 Ig-71 45 rs560562125 0.7274 -0.086 0.92 N 0.329 0.257 0.260735089382 gnomAD-4.0.0 6.57255E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.0842E-04 0
G/A 8686 Ig-72 44 None 0.1531 None 0.062 N 0.453 0.108 0.101711395817 gnomAD-4.0.0 6.84242E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.1595E-05 0
G/S 8686 Ig-72 44 rs370578197 0.0674 -0.258 0.002 N 0.231 0.046 None gnomAD-2.1.1 8.92E-05 None None None None N None 1.24028E-04 4.80606E-04 None 0 5.12E-05 None 0 None 4E-05 2.34E-05 0
G/S 8686 Ig-72 44 rs370578197 0.0674 -0.258 0.002 N 0.231 0.046 None gnomAD-3.1.2 5.26E-05 None None None None N None 1.69066E-04 0 0 0 0 None 0 0 1.47E-05 0 0
G/S 8686 Ig-72 44 rs370578197 0.0674 -0.258 0.002 N 0.231 0.046 None gnomAD-4.0.0 3.0988E-05 None None None None N None 1.46949E-04 3.16751E-04 None 0 2.22806E-05 None 0 3.28947E-04 1.27151E-05 1.09801E-05 1.60113E-05
G/V 8686 Ig-72 44 None 0.2939 None 0.865 N 0.62 0.218 0.537915542499 gnomAD-4.0.0 1.36848E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79904E-06 0 0
S/G 8780 Ig-73 45 None 0.096 None 0.001 N 0.143 0.075 0.0762999501168 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
S/N 8780 Ig-73 45 rs764652580 0.1481 -0.256 0.083 N 0.435 0.262 0.0920862733494 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
S/N 8780 Ig-73 45 rs764652580 0.1481 -0.256 0.083 N 0.435 0.262 0.0920862733494 gnomAD-4.0.0 1.77904E-05 None None None None N None 0 0 None 0 0 None 0 0 2.33872E-05 0 0
S/R 8780 Ig-73 45 rs756708089 0.6979 -0.324 0.953 N 0.339 0.272 0.306377322295 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
S/R 8780 Ig-73 45 rs756708089 0.6979 -0.324 0.953 N 0.339 0.272 0.306377322295 gnomAD-4.0.0 1.59146E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85863E-06 0 0
D/E 8873 Ig-74 44 rs772596633 0.2311 -0.004 0.961 N 0.35 0.179 0.16115917748 gnomAD-2.1.1 1.32209E-04 None None None None N None 8.27E-05 9.92851E-04 None 0 0 None 0 None 0 0 0
D/E 8873 Ig-74 44 rs772596633 0.2311 -0.004 0.961 N 0.35 0.179 0.16115917748 gnomAD-3.1.2 4.6E-05 None None None None N None 2.41E-05 3.93185E-04 0 0 0 None 0 0 0 0 0
D/E 8873 Ig-74 44 rs772596633 0.2311 -0.004 0.961 N 0.35 0.179 0.16115917748 gnomAD-4.0.0 8.07342E-05 None None None None N None 3.38375E-05 1.01767E-03 None 0 0 None 0 0 0 0 2.84544E-05
D/G 8873 Ig-74 44 rs776032171 0.1156 -0.372 0.031 N 0.265 0.127 0.0954503805726 gnomAD-2.1.1 7.15E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.56E-05 0
D/G 8873 Ig-74 44 rs776032171 0.1156 -0.372 0.031 N 0.265 0.127 0.0954503805726 gnomAD-4.0.0 4.10585E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39726E-06 0 0
G/D 9062 Ig-76 44 rs2076863963 0.2103 None 0.956 N 0.429 0.248 0.168933306366 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/D 9062 Ig-76 44 rs2076863963 0.2103 None 0.956 N 0.429 0.248 0.168933306366 gnomAD-4.0.0 6.57142E-06 None None None None N None 2.41255E-05 0 None 0 0 None 0 0 0 0 0
G/R 9062 Ig-76 44 rs1287177900 0.3039 -0.046 0.997 N 0.521 0.271 0.464270400615 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
G/R 9062 Ig-76 44 rs1287177900 0.3039 -0.046 0.997 N 0.521 0.271 0.464270400615 gnomAD-4.0.0 6.84233E-07 None None None None N None 0 0 None 0 2.52067E-05 None 0 0 0 0 0
G/S 9062 Ig-76 44 None 0.1015 None 0.63 N 0.256 0.109 0.107399877778 gnomAD-4.0.0 6.84233E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9947E-07 0 0
S/C 9155 Ig-77 44 rs774307822 0.2009 -0.364 1.0 N 0.669 0.427 0.484109215787 gnomAD-2.1.1 8.03E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
S/C 9155 Ig-77 44 rs774307822 0.2009 -0.364 1.0 N 0.669 0.427 0.484109215787 gnomAD-4.0.0 4.10512E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.9562E-05 0
S/F 9155 Ig-77 44 rs774307822 0.3187 -0.84 1.0 D 0.697 0.464 0.665400188923 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
S/P 9155 Ig-77 44 None 0.7858 None 1.0 N 0.629 0.414 0.354396617058 gnomAD-4.0.0 1.59115E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85798E-06 0 0
T/I 9248 Ig-78 44 rs397517523 0.3894 -0.126 0.379 N 0.263 0.203 0.288727942641 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
T/I 9248 Ig-78 44 rs397517523 0.3894 -0.126 0.379 N 0.263 0.203 0.288727942641 gnomAD-4.0.0 6.84213E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99473E-07 0 0
T/N 9248 Ig-78 44 rs397517523 0.1324 None 0.379 N 0.358 0.154 0.216624796971 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 1.92976E-04 None 0 0 1.47E-05 0 0
T/N 9248 Ig-78 44 rs397517523 0.1324 None 0.379 N 0.358 0.154 0.216624796971 gnomAD-4.0.0 6.81618E-06 None None None None N None 1.33287E-05 0 None 0 2.22886E-05 None 0 0 5.08569E-06 0 4.80169E-05
S/R 9344 Ig-79 44 rs1338895544 0.429 0.066 0.106 None 0.327 0.174 0.223146558224 gnomAD-2.1.1 4.01E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
S/R 9344 Ig-79 44 rs1338895544 0.429 0.066 0.106 None 0.327 0.174 0.223146558224 gnomAD-4.0.0 6.84182E-07 None None None None N None 0 2.23604E-05 None 0 0 None 0 0 0 0 0
G/R 9440 Ig-80 44 rs940069606 0.4668 None 1.0 None 0.751 0.448 0.5343833383 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
T/I 9537 Ig-81 45 None 0.3075 None 0.627 None 0.333 0.101 0.311387274539 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
G/A 9742 Ig-83 45 rs1461138247 0.4182 None 1.0 None 0.581 0.407 0.268211541103 gnomAD-4.0.0 1.59103E-06 None None None None N None 5.65355E-05 0 None 0 0 None 0 0 0 0 0
G/E 9742 Ig-83 45 rs1461138247 0.9339 -0.299 1.0 None 0.733 0.404 0.366085729538 gnomAD-2.1.1 7.13E-06 None None None None N None 4.13E-05 2.83E-05 None 0 0 None 0 None 0 0 0
G/E 9742 Ig-83 45 rs1461138247 0.9339 -0.299 1.0 None 0.733 0.404 0.366085729538 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
G/E 9742 Ig-83 45 rs1461138247 0.9339 -0.299 1.0 None 0.733 0.404 0.366085729538 gnomAD-4.0.0 2.5619E-06 None None None None N None 1.69142E-05 0 None 0 0 None 0 0 0 1.34009E-05 0
S/N 9944 Ig-84 45 rs766917273 0.2071 -0.11 0.026 None 0.152 0.066 0.148003135375 gnomAD-2.1.1 4.07E-06 None None None None N None 0 0 None 0 0 None 3.3E-05 None 0 0 0
S/N 9944 Ig-84 45 rs766917273 0.2071 -0.11 0.026 None 0.152 0.066 0.148003135375 gnomAD-4.0.0 1.36974E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.3238E-05 0
S/T 9944 Ig-84 45 rs766917273 0.1129 -0.113 0.896 None 0.471 0.214 0.211220785272 gnomAD-2.1.1 4.07E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.02E-06 0
S/T 9944 Ig-84 45 rs766917273 0.1129 -0.113 0.896 None 0.471 0.214 0.211220785272 gnomAD-4.0.0 6.8487E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00108E-07 0 0
S/G 10120 Ig-86 43 rs1577676588 0.4052 None 0.104 None 0.243 0.129 0.0551355673512 gnomAD-4.0.0 1.20033E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
S/R 10120 Ig-86 43 rs1292517657 0.9941 -0.142 0.999 None 0.495 0.281 0.227934060464 gnomAD-2.1.1 4.01E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
S/R 10120 Ig-86 43 rs1292517657 0.9941 -0.142 0.999 None 0.495 0.281 0.227934060464 gnomAD-4.0.0 6.84134E-07 None None None None N None 0 2.23594E-05 None 0 0 None 0 0 0 0 0
S/G 13729 Ig-87 46 rs1372970593 0.1811 -0.764 0.999 N 0.461 0.191 0.188950314367 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
S/G 13729 Ig-87 46 rs1372970593 0.1811 -0.764 0.999 N 0.461 0.191 0.188950314367 gnomAD-4.0.0 4.10599E-06 None None None None N None 0 2.23654E-05 None 0 0 None 0 0 4.49801E-06 0 0
S/R 13729 Ig-87 46 rs1303644206 0.9913 -0.448 1.0 N 0.629 0.525 0.293502639404 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
N/D 13918 Ig-89 43 rs2060334868 0.1396 None 0.011 N 0.409 0.126 0.130388298395 gnomAD-4.0.0 3.46618E-06 None None None None N None 9.00793E-05 0 None 0 0 None 0 0 9.0812E-07 0 1.67482E-05
N/K 13918 Ig-89 43 rs1396769268 0.6558 -0.127 0.011 N 0.336 0.021 0.0611884634855 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
N/K 13918 Ig-89 43 rs1396769268 0.6558 -0.127 0.011 N 0.336 0.021 0.0611884634855 gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
N/K 13918 Ig-89 43 rs1396769268 0.6558 -0.127 0.011 N 0.336 0.021 0.0611884634855 gnomAD-4.0.0 1.3152E-05 None None None None N None 4.82532E-05 0 None 0 0 None 0 0 0 0 0
S/F 14095 Ig-91 42 rs762662244 0.8028 -1.187 0.989 D 0.447 0.346 0.505518066752 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
S/F 14095 Ig-91 42 rs762662244 0.8028 -1.187 0.989 D 0.447 0.346 0.505518066752 gnomAD-4.0.0 1.59237E-06 None None None None N None 0 0 None 0 2.77639E-05 None 0 0 0 0 0
S/C 14361 Ig-94 43 None 0.2732 None 1.0 N 0.743 0.451 0.300110245524 gnomAD-4.0.0 6.8571E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.6613E-05
S/Y 14361 Ig-94 43 None 0.3978 None 0.999 D 0.798 0.481 0.523806315272 gnomAD-4.0.0 1.37142E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80224E-06 0 0
S/F 14628 Ig-97 43 None 0.4762 None 1.0 D 0.751 0.467 0.541692676538 gnomAD-4.0.0 1.59238E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85963E-06 0 0
S/T 14806 Ig-99 42 rs778340859 0.0972 -0.225 0.124 N 0.459 0.092 0.0986583533028 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 1.13289E-04 None 0 None 0 0 0
S/T 14806 Ig-99 42 rs778340859 0.0972 -0.225 0.124 N 0.459 0.092 0.0986583533028 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94401E-04 None 0 0 0 0 0
S/T 14806 Ig-99 42 rs778340859 0.0972 -0.225 0.124 N 0.459 0.092 0.0986583533028 gnomAD-4.0.0 2.56689E-06 None None None None N None 0 0 None 0 4.88257E-05 None 0 0 0 0 0
S/C 14895 Ig-100 43 None 0.2743 None 0.99 N 0.315 0.262 0.200317383148 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
S/I 14895 Ig-100 43 None 0.663 None 0.81 N 0.417 0.155 None gnomAD-4.0.0 4.78063E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.29947E-05 0
G/C 14984 Ig-101 43 rs555721876 0.7034 -0.37 1.0 N 0.694 0.402 0.366848117066 gnomAD-2.1.1 4.08E-06 None None None None N None 0 0 None 0 0 None 3.29E-05 None 0 0 0
G/C 14984 Ig-101 43 rs555721876 0.7034 -0.37 1.0 N 0.694 0.402 0.366848117066 gnomAD-3.1.2 6.59E-06 None None None None N None 0 6.58E-05 0 0 0 None 0 0 0 0 0
G/C 14984 Ig-101 43 rs555721876 0.7034 -0.37 1.0 N 0.694 0.402 0.366848117066 gnomAD-4.0.0 1.24192E-06 None None None None N None 0 1.67774E-05 None 0 0 None 0 0 0 1.10076E-05 0
G/D 14984 Ig-101 43 rs1190798574 0.6204 None 1.0 N 0.639 0.421 0.252162846088 gnomAD-4.0.0 1.59892E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87028E-06 0 0
G/R 14984 Ig-101 43 rs555721876 0.8801 -0.213 1.0 D 0.68 0.426 0.325533332567 gnomAD-2.1.1 3.67E-05 None None None None N None 0 0 None 0 5.13699E-04 None 0 None 0 0 0
G/R 14984 Ig-101 43 rs555721876 0.8801 -0.213 1.0 D 0.68 0.426 0.325533332567 gnomAD-3.1.2 6.59E-06 None None None None N None 0 0 0 0 1.95313E-04 None 0 0 0 0 0
G/R 14984 Ig-101 43 rs555721876 0.8801 -0.213 1.0 D 0.68 0.426 0.325533332567 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
G/R 14984 Ig-101 43 rs555721876 0.8801 -0.213 1.0 D 0.68 0.426 0.325533332567 gnomAD-4.0.0 9.93463E-06 None None None None N None 0 0 None 0 2.92319E-04 None 0 0 8.48768E-07 0 3.20914E-05
T/A 15073 Ig-102 43 rs1444196912 0.101 -0.466 0.139 N 0.223 0.161 0.26547132957 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
T/A 15073 Ig-102 43 rs1444196912 0.101 -0.466 0.139 N 0.223 0.161 0.26547132957 gnomAD-4.0.0 4.79256E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39944E-06 0 1.65837E-05
G/E 15162 Ig-103 43 None 0.3486 None 0.999 N 0.7 0.304 0.322510055762 gnomAD-4.0.0 1.59429E-06 None None None None N None 0 0 None 0 0 None 1.88466E-05 0 0 0 0
S/C 15250 Ig-104 43 rs776190494 0.3154 -0.265 1.0 D 0.543 0.472 0.444305618086 gnomAD-2.1.1 8.08E-05 None None None None N None 0 0 None 0 0 None 6.54065E-04 None 0 0 0
S/C 15250 Ig-104 43 rs776190494 0.3154 -0.265 1.0 D 0.543 0.472 0.444305618086 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 0 4.14079E-04 0
S/C 15250 Ig-104 43 rs776190494 0.3154 -0.265 1.0 D 0.543 0.472 0.444305618086 gnomAD-4.0.0 4.03089E-05 None None None None N None 0 0 None 0 0 None 0 0 0 6.91943E-04 3.20523E-05
S/G 15250 Ig-104 43 None 0.17 None 0.104 N 0.275 0.15 0.187945064343 gnomAD-4.0.0 6.84641E-07 None None None None N None 0 2.23994E-05 None 0 0 None 0 0 0 0 0
S/T 15250 Ig-104 43 None 0.1631 None 0.994 N 0.449 0.237 0.276898752692 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/G 15344 Ig-105 43 None 0.2339 None 0.454 N 0.333 0.138 0.134241683229 gnomAD-4.0.0 1.59412E-06 None None None None N None 0 0 None 0 0 None 1.88331E-05 0 0 0 0
G/C 15433 Ig-106 43 None 0.5467 None 0.997 D 0.776 0.416 0.666410456768 gnomAD-4.0.0 7.22964E-07 None None None None N None 0 0 None 0 0 None 0 0 9.27869E-07 0 0
G/D 15433 Ig-106 43 rs1553715070 0.3844 -0.047 0.957 N 0.645 0.335 0.325263233342 gnomAD-2.1.1 5.36E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.1E-05 0
G/D 15433 Ig-106 43 rs1553715070 0.3844 -0.047 0.957 N 0.645 0.335 0.325263233342 gnomAD-4.0.0 1.81664E-06 None None None None N None 0 0 None 0 0 None 0 0 3.16552E-06 0 0
G/R 15522 Ig-107 43 rs750435043 0.8926 -0.209 1.0 D 0.766 0.476 0.639656643812 gnomAD-2.1.1 3.22E-05 None None None None N None 0 0 None 0 0 None 0 None 0 7.13E-05 0
G/R 15522 Ig-107 43 rs750435043 0.8926 -0.209 1.0 D 0.766 0.476 0.639656643812 gnomAD-3.1.2 2.64E-05 None None None None N None 2.42E-05 0 0 0 0 None 0 0 4.42E-05 0 0
G/R 15522 Ig-107 43 rs750435043 0.8926 -0.209 1.0 D 0.766 0.476 0.639656643812 gnomAD-4.0.0 8.12541E-05 None None None None N None 1.33797E-05 0 None 0 0 None 0 0 1.09422E-04 0 1.60292E-05
G/V 15522 Ig-107 43 rs1246339782 0.8664 None 1.0 D 0.778 0.517 0.643109767165 gnomAD-4.0.0 1.59392E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43365E-05 0
D/E 16302 Ig-110 41 rs2056963801 0.4017 None 1.0 N 0.456 0.202 0.245101548738 gnomAD-4.0.0 6.84735E-07 None None None None N None 0 0 None 0 2.53254E-05 None 0 0 0 0 0
S/N 16998 Ig-111 44 rs749043514 0.1255 -0.072 None N 0.139 0.087 0.0806252709748 gnomAD-2.1.1 1.21E-05 None None None None N None 0 2.9E-05 None 0 0 None 3.27E-05 None 4.65E-05 0 0
S/N 16998 Ig-111 44 rs749043514 0.1255 -0.072 None N 0.139 0.087 0.0806252709748 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 0 2.07125E-04 4.78469E-04
S/N 16998 Ig-111 44 rs749043514 0.1255 -0.072 None N 0.139 0.087 0.0806252709748 gnomAD-4.0.0 8.97889E-06 None None None None N None 0 0 None 0 0 None 1.56897E-05 0 2.39617E-06 5.36207E-05 2.84852E-05
E/Q 17291 Ig-112 41 None 0.1437 None 0.984 N 0.721 0.214 0.391775403332 gnomAD-4.0.0 1.59434E-06 None None None None N None 5.67666E-05 0 None 0 0 None 0 0 0 0 0
P/S 18010 Ig-114 43 None 0.1091 None 0.022 N 0.281 0.099 0.16115917748 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
N/D 18728 Ig-116 41 None 0.0738 None None N 0.116 0.089 0.181679512989 gnomAD-4.0.0 4.10717E-06 None None None None N None 0 0 None 0 0 None 0 1.73732E-04 4.49892E-06 0 0
N/K 18728 Ig-116 41 rs2052768843 0.1387 None None N 0.116 0.079 0.0762999501168 gnomAD-4.0.0 6.84544E-07 None None None None N None 2.99204E-05 0 None 0 0 None 0 0 0 0 0
E/D 19136 Ig-117 42 rs553505206 0.1489 -0.108 0.999 N 0.522 0.126 0.167679373172 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94175E-04 None 0 0 0 0 0
E/D 19136 Ig-117 42 rs553505206 0.1489 -0.108 0.999 N 0.522 0.126 0.167679373172 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
E/D 19136 Ig-117 42 rs553505206 0.1489 -0.108 0.999 N 0.522 0.126 0.167679373172 gnomAD-4.0.0 3.8448E-06 None None None None N None 0 0 None 0 2.43285E-05 None 0 0 0 1.34016E-05 2.84382E-05
E/G 19136 Ig-117 42 None 0.2099 None 1.0 N 0.648 0.374 0.28058544554 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
D/N 19430 Ig-118 40 None 0.1572 None 0.322 N 0.263 0.112 0.17948927462 gnomAD-4.0.0 1.59201E-06 None None None None N None 0 0 None 0 0 None 0 2.41429E-04 0 0 0
K/R 19830 Ig-119 41 rs764259290 0.0816 -0.022 0.003 N 0.172 0.077 None gnomAD-2.1.1 1.79E-05 None None None None N None 2.06714E-04 0 None 0 0 None 0 None 0 0 0
K/R 19830 Ig-119 41 rs764259290 0.0816 -0.022 0.003 N 0.172 0.077 None gnomAD-3.1.2 9.86E-05 None None None None N None 3.37756E-04 0 0 0 0 None 0 0 0 0 4.78011E-04
K/R 19830 Ig-119 41 rs764259290 0.0816 -0.022 0.003 N 0.172 0.077 None gnomAD-4.0.0 2.3068E-05 None None None None N None 2.8758E-04 0 None 0 0 None 0 0 0 0 2.84479E-05
D/N 20122 Ig-120 43 rs776191153 0.0802 0.128 0.021 N 0.149 0.061 None gnomAD-2.1.1 2.86E-05 None None None None N None 4.13E-05 0 None 0 0 None 0 None 0 5.48E-05 0
D/N 20122 Ig-120 43 rs776191153 0.0802 0.128 0.021 N 0.149 0.061 None gnomAD-3.1.2 5.26E-05 None None None None N None 4.83E-05 0 0 2.88018E-04 0 None 0 0 7.36E-05 0 0
D/N 20122 Ig-120 43 rs776191153 0.0802 0.128 0.021 N 0.149 0.061 None gnomAD-4.0.0 8.74065E-05 None None None None N None 2.67158E-05 0 None 3.38021E-05 0 None 0 0 1.16154E-04 0 1.60185E-05
S/P 21510 Ig-124 42 None 0.8652 None 1.0 N 0.727 0.518 0.36893422563 gnomAD-4.0.0 1.59229E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43353E-05 0
R/G 22305 Ig-126 41 None 0.8879 None 1.0 N 0.64 0.361 0.194818534648 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/T 22305 Ig-126 41 None 0.8698 None 1.0 N 0.717 0.466 0.278968121808 gnomAD-4.0.0 1.59277E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86072E-06 0 0
D/V 22594 Ig-127 35 rs369911767 0.5117 0.193 0.949 N 0.565 0.237 None gnomAD-2.1.1 2.41E-05 None None None None N None 3.87747E-04 0 None 0 0 None 0 None 0 0 0
D/V 22594 Ig-127 35 rs369911767 0.5117 0.193 0.949 N 0.565 0.237 None gnomAD-3.1.2 8.55E-05 None None None None N None 2.89561E-04 6.56E-05 0 0 0 None 0 0 0 0 0
D/V 22594 Ig-127 35 rs369911767 0.5117 0.193 0.949 N 0.565 0.237 None gnomAD-4.0.0 1.36365E-05 None None None None N None 2.80419E-04 1.6675E-05 None 0 0 None 0 0 0 0 0
R/G 23388 Ig-129 44 rs781540455 0.7553 -0.553 1.0 N 0.632 0.402 0.484109215787 gnomAD-2.1.1 7.15E-06 None None None None N None 0 2.83E-05 None 0 0 None 0 None 0 7.81E-06 0
R/G 23388 Ig-129 44 rs781540455 0.7553 -0.553 1.0 N 0.632 0.402 0.484109215787 gnomAD-3.1.2 1.97E-05 None None None None N None 0 6.56E-05 0 0 0 None 0 3.16456E-03 1.47E-05 0 0
R/G 23388 Ig-129 44 rs781540455 0.7553 -0.553 1.0 N 0.632 0.402 0.484109215787 gnomAD-4.0.0 6.20683E-06 None None None None N None 0 1.66867E-05 None 0 0 None 0 1.64962E-04 5.94327E-06 0 1.60344E-05
R/Q 23388 Ig-129 44 rs55853138 0.2342 0.163 1.0 N 0.675 0.338 None gnomAD-2.1.1 6.07E-05 None None None None N None 0 0 None 0 5.13E-05 None 0 None 4.02E-05 1.17186E-04 0
R/Q 23388 Ig-129 44 rs55853138 0.2342 0.163 1.0 N 0.675 0.338 None gnomAD-3.1.2 7.23E-05 None None None None N None 0 0 0 0 0 None 9.43E-05 0 1.47098E-04 0 0
R/Q 23388 Ig-129 44 rs55853138 0.2342 0.163 1.0 N 0.675 0.338 None gnomAD-4.0.0 6.33061E-05 None None None None N None 0 0 None 0 2.23294E-05 None 3.13156E-05 0 8.1505E-05 2.19785E-05 1.60323E-05
T/I 24073 Ig-131 45 None 0.3778 None 0.565 N 0.387 0.234 0.256793551483 gnomAD-4.0.0 2.05464E-06 None None None None N None 0 0 None 0 0 None 1.87406E-05 0 1.80045E-06 0 0
T/R 24073 Ig-131 45 rs753519331 0.2377 0.218 0.949 N 0.402 0.203 0.257786959452 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 1.3107E-04 None 0 0 0
T/R 24073 Ig-131 45 rs753519331 0.2377 0.218 0.949 N 0.402 0.203 0.257786959452 gnomAD-4.0.0 6.84881E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.16044E-04 0
K/N 24472 Ig-132 42 rs1239070012 0.3315 -0.713 0.896 N 0.453 0.112 0.166414681773 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.65948E-04
K/N 24472 Ig-132 42 rs1239070012 0.3315 -0.713 0.896 N 0.453 0.112 0.166414681773 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/N 24472 Ig-132 42 rs1239070012 0.3315 -0.713 0.896 N 0.453 0.112 0.166414681773 gnomAD-4.0.0 3.84493E-06 None None None None N None 0 0 None 0 0 None 0 0 4.78822E-06 0 2.84527E-05
T/I 24759 Ig-133 44 rs1421105301 0.9476 0.051 0.994 N 0.689 0.45 0.412980791724 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
T/I 24759 Ig-133 44 rs1421105301 0.9476 0.051 0.994 N 0.689 0.45 0.412980791724 gnomAD-4.0.0 1.59175E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85932E-06 0 0
T/I 25155 Ig-134 45 None 0.3932 None 0.998 N 0.456 0.401 0.437314048365 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
A/G 25554 Ig-135 41 rs879087699 0.1176 -0.064 0.201 N 0.325 0.169 None gnomAD-2.1.1 7.16E-06 None None None None N None 8.27E-05 0 None 0 0 None 0 None 0 0 0
A/G 25554 Ig-135 41 rs879087699 0.1176 -0.064 0.201 N 0.325 0.169 None gnomAD-3.1.2 3.29E-05 None None None None N None 1.20715E-04 0 0 0 0 None 0 0 0 0 0
A/G 25554 Ig-135 41 rs879087699 0.1176 -0.064 0.201 N 0.325 0.169 None gnomAD-4.0.0 4.34072E-06 None None None None N None 8.0156E-05 0 None 0 0 None 0 0 0 0 1.6022E-05
T/I 25841 Ig-136 44 None 0.9448 None 1.0 N 0.717 0.445 0.412328234245 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
S/F 26237 Ig-137 45 rs1706305589 0.4814 None 0.901 N 0.537 0.374 0.515430650102 gnomAD-4.0.0 1.60647E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87747E-06 0 0
K/E 26636 Ig-138 43 None 0.4322 None 0.977 N 0.457 0.277 0.20549828249 gnomAD-4.0.0 1.59146E-06 None None None None N None 0 0 None 0 2.77393E-05 None 0 0 0 0 0
T/I 26923 Ig-139 44 None 0.9503 None 0.988 N 0.652 0.428 0.402326594622 gnomAD-4.0.0 1.36857E-06 None None None None N None 0 0 None 0 2.51991E-05 None 0 0 8.99549E-07 0 0
T/K 26923 Ig-139 44 rs2154164717 0.8447 None 0.988 N 0.625 0.427 0.355865052028 gnomAD-4.0.0 6.84284E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15955E-05 0
T/I 27319 Ig-140 42 rs1175606376 0.1344 0.101 0.193 N 0.351 0.159 0.244539031024 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.94E-06 0
R/G 27719 Ig-141 44 rs929458467 0.4303 None 0.025 N 0.385 0.206 0.319686207203 gnomAD-4.0.0 2.40064E-06 None None None None I None 1.26695E-04 0 None 0 0 None 0 0 0 0 0
R/S 27719 Ig-141 44 rs1342825597 0.6656 0.194 0.892 N 0.457 0.291 0.327952845175 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
R/S 27719 Ig-141 44 rs1342825597 0.6656 0.194 0.892 N 0.457 0.291 0.327952845175 gnomAD-4.0.0 1.59155E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85855E-06 0 0
R/G 28401 Ig-143 44 None 0.1093 None 0.285 N 0.234 0.175 0.326616659874 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/K 28401 Ig-143 44 None 0.0782 None None N 0.105 0.091 0.0846915920261 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
R/G 28798 Ig-144 44 rs748375797 0.5881 -0.295 0.939 N 0.432 0.288 0.533035250729 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.49E-05 0
R/G 28798 Ig-144 44 rs748375797 0.5881 -0.295 0.939 N 0.432 0.288 0.533035250729 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/G 28798 Ig-144 44 rs748375797 0.5881 -0.295 0.939 N 0.432 0.288 0.533035250729 gnomAD-4.0.0 6.57203E-06 None None None None N None 0 0 None 0 0 None 0 0 1.46998E-05 0 0
R/I 28798 Ig-144 44 None 0.5184 None 0.991 N 0.573 0.409 0.738858788324 gnomAD-4.0.0 1.62837E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.49058E-05 0
R/K 28798 Ig-144 44 rs781458689 0.173 0.095 0.76 N 0.507 0.307 0.229264304666 gnomAD-2.1.1 8.45E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.85E-05 0
R/K 28798 Ig-144 44 rs781458689 0.173 0.095 0.76 N 0.507 0.307 0.229264304666 gnomAD-4.0.0 7.82918E-06 None None None None N None 3.39121E-05 0 None 0 0 None 0 0 9.74778E-06 0 0
T/I 29088 Ig-145 44 rs565333965 0.7709 -0.083 0.235 N 0.272 0.4 0.319686207203 gnomAD-2.1.1 2.41E-05 None None None None N None 0 0 None 0 3.34374E-04 None 0 None 0 0 0
T/I 29088 Ig-145 44 rs565333965 0.7709 -0.083 0.235 N 0.272 0.4 0.319686207203 gnomAD-3.1.2 2.63E-05 None None None None N None 0 0 0 0 7.71307E-04 None 0 0 0 0 0
T/I 29088 Ig-145 44 rs565333965 0.7709 -0.083 0.235 N 0.272 0.4 0.319686207203 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
T/I 29088 Ig-145 44 rs565333965 0.7709 -0.083 0.235 N 0.272 0.4 0.319686207203 gnomAD-4.0.0 5.88637E-05 None None None None N None 0 0 None 0 2.09513E-03 None 0 0 0 0 1.60031E-05
T/P 29088 Ig-145 44 rs1252696671 0.4316 -0.511 0.999 N 0.603 0.471 0.360565625551 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
T/P 29088 Ig-145 44 rs1252696671 0.4316 -0.511 0.999 N 0.603 0.471 0.360565625551 gnomAD-4.0.0 1.59103E-06 None None None None N None 0 2.28624E-05 None 0 0 None 0 0 0 0 0
N/K 29484 Ig-146 41 None 0.4483 None 0.379 N 0.225 0.078 0.115124310173 gnomAD-4.0.0 1.59155E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
N/S 29484 Ig-146 41 None 0.0722 None 0.002 N 0.113 0.115 0.0762999501168 gnomAD-4.0.0 2.05278E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69839E-06 0 0
S/G 30175 Ig-148 44 rs201060254 0.1208 -0.288 0.939 N 0.375 0.205 0.137902524267 gnomAD-2.1.1 2.15E-05 None None None None N None 0 0 None 0 5.67E-05 None 0 None 0 3.74E-05 0
S/G 30175 Ig-148 44 rs201060254 0.1208 -0.288 0.939 N 0.375 0.205 0.137902524267 gnomAD-4.0.0 1.15489E-05 None None None None N None 0 2.37462E-05 None 0 2.80002E-05 None 0 0 1.18523E-05 0 3.12149E-05
S/R 30175 Ig-148 44 rs1220880668 0.9032 0.021 0.991 N 0.469 0.394 0.16115917748 gnomAD-2.1.1 7.58E-06 None None None None N None 4.17E-05 2.98E-05 None 0 0 None 0 None 0 0 0
S/R 30175 Ig-148 44 rs1220880668 0.9032 0.021 0.991 N 0.469 0.394 0.16115917748 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
S/R 30175 Ig-148 44 rs1220880668 0.9032 0.021 0.991 N 0.469 0.394 0.16115917748 gnomAD-4.0.0 2.6377E-06 None None None None N None 1.70928E-05 1.74392E-05 None 0 0 None 0 0 0 0 0
S/T 30175 Ig-148 44 None 0.0795 None 0.17 N 0.273 0.069 0.0716867268079 gnomAD-4.0.0 1.64977E-06 None None None None N None 0 0 None 0 0 None 0 0 2.96238E-06 0 0
R/T 30570 Ig-149 39 None 0.1427 None 0.001 N 0.231 0.038 0.0401082797425 gnomAD-4.0.0 1.59126E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43283E-05 0
R/P 30969 Ig-150 43 None 0.8229 None 0.992 N 0.422 0.341 0.349204839081 gnomAD-4.0.0 6.84213E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99457E-07 0 0
R/Q 30969 Ig-150 43 rs751345368 0.1259 0.114 0.924 N 0.361 0.229 0.184867976434 gnomAD-2.1.1 8.04E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
R/Q 30969 Ig-150 43 rs751345368 0.1259 0.114 0.924 N 0.361 0.229 0.184867976434 gnomAD-4.0.0 5.47371E-06 None None None None N None 0 4.47247E-05 None 0 0 None 0 0 4.49728E-06 0 1.65656E-05
R/W 30969 Ig-150 43 rs754767262 0.2169 -0.499 0.999 N 0.426 0.375 0.504848970537 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 1.77E-05 0
R/W 30969 Ig-150 43 rs754767262 0.2169 -0.499 0.999 N 0.426 0.375 0.504848970537 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 3.16456E-03 0 0 0
R/W 30969 Ig-150 43 rs754767262 0.2169 -0.499 0.999 N 0.426 0.375 0.504848970537 gnomAD-4.0.0 1.54913E-05 None None None None N None 0 8.33028E-05 None 0 2.22866E-05 None 0 1.64962E-04 1.44092E-05 1.09794E-05 0
T/A 31259 Ig-151 42 None 0.2858 None 0.981 N 0.455 0.288 0.202949470691 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
C/Y 31659 Ig-152 39 rs747276133 0.2343 -0.818 0.975 N 0.427 0.382 0.532263770911 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
C/Y 31659 Ig-152 39 rs747276133 0.2343 -0.818 0.975 N 0.427 0.382 0.532263770911 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
C/Y 31659 Ig-152 39 rs747276133 0.2343 -0.818 0.975 N 0.427 0.382 0.532263770911 gnomAD-4.0.0 6.57367E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47011E-05 0 0
S/P 32350 Ig-154 44 None 0.6508 None 0.989 N 0.319 0.241 0.245660935333 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
G/R 33540 Ig-158 45 None 0.6187 None 1.0 D 0.723 0.571 0.775112900452 gnomAD-4.0.0 1.59166E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85886E-06 0 0
G/V 33540 Ig-158 45 rs1691396278 0.5618 None 1.0 N 0.725 0.538 0.880811135049 gnomAD-4.0.0 1.59171E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02572E-05
N/Y 33639 Ig-159 44 rs752173646 0.4712 -0.56 0.995 N 0.382 0.317 0.409665357357 gnomAD-2.1.1 1.79E-05 None None None None N None 0 0 None 0 0 None 0 None 1.59974E-04 7.82E-06 0
N/Y 33639 Ig-159 44 rs752173646 0.4712 -0.56 0.995 N 0.382 0.317 0.409665357357 gnomAD-3.1.2 3.94E-05 None None None None N None 0 0 0 0 0 None 4.70898E-04 0 1.47E-05 0 0
N/Y 33639 Ig-159 44 rs752173646 0.4712 -0.56 0.995 N 0.382 0.317 0.409665357357 gnomAD-4.0.0 1.2811E-05 None None None None N None 0 0 None 0 0 None 1.09859E-04 0 4.78611E-06 0 2.84446E-05
S/G 34180 Ig-160 44 None 0.1545 None 0.001 N 0.211 0.1 0.0884992946249 gnomAD-4.0.0 3.18201E-06 None None None None N None 0 0 None 0 0 None 3.76478E-05 0 0 0 0
S/I 34180 Ig-160 44 None 0.6558 None 0.667 N 0.478 0.216 0.482792760554 gnomAD-4.0.0 1.591E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85773E-06 0 0
S/N 34180 Ig-160 44 rs1254821683 0.211 -0.037 0.001 N 0.203 0.11 0.0806252709748 gnomAD-2.1.1 1.2E-05 None None None None N None 0 8.69E-05 None 0 0 None 0 None 0 0 0
S/N 34180 Ig-160 44 rs1254821683 0.211 -0.037 0.001 N 0.203 0.11 0.0806252709748 gnomAD-4.0.0 6.36402E-06 None None None None N None 0 9.14578E-05 None 0 0 None 0 0 0 0 0
S/R 34180 Ig-160 44 None 0.8504 None 0.497 N 0.371 0.233 0.284150004643 gnomAD-4.0.0 1.591E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85771E-06 0 0
G/E 34406 Ig-162 44 rs1346830355 0.6861 -0.285 0.901 N 0.477 0.397 0.589843679045 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
G/E 34406 Ig-162 44 rs1346830355 0.6861 -0.285 0.901 N 0.477 0.397 0.589843679045 gnomAD-4.0.0 3.18307E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86549E-05 0
G/R 34406 Ig-162 44 rs371753532 0.7534 -0.155 0.195 N 0.394 0.256 0.592943046075 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 1.77E-05 0
G/R 34406 Ig-162 44 rs371753532 0.7534 -0.155 0.195 N 0.394 0.256 0.592943046075 gnomAD-4.0.0 1.30011E-05 None None None None N None 0 0 None 0 2.51902E-05 None 1.88104E-05 0 1.25919E-05 3.4781E-05 0
S/G 34985 Ig-163 44 rs765030518 0.1632 -0.417 0.994 N 0.409 0.215 0.144782658237 gnomAD-2.1.1 2.41E-05 None None None None N None 0 0 None 0 5.56E-05 None 0 None 0 3.54E-05 1.65289E-04
S/G 34985 Ig-163 44 rs765030518 0.1632 -0.417 0.994 N 0.409 0.215 0.144782658237 gnomAD-4.0.0 2.3945E-05 None None None None N None 2.98704E-05 0 None 0 2.51889E-05 None 0 0 2.96802E-05 0 0
S/F 35172 Ig-164 44 rs749354699 0.3331 -0.905 0.999 N 0.605 0.476 0.582419091513 gnomAD-2.1.1 1.78E-05 None None None None N None 0 1.41347E-04 None 0 0 None 0 None 0 0 0
S/F 35172 Ig-164 44 rs749354699 0.3331 -0.905 0.999 N 0.605 0.476 0.582419091513 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.96386E-04 0 0 0 None 0 0 0 0 0
S/F 35172 Ig-164 44 rs749354699 0.3331 -0.905 0.999 N 0.605 0.476 0.582419091513 gnomAD-4.0.0 8.97273E-06 None None None None N None 0 1.1862E-04 None 0 0 None 0 0 0 0 0
S/Y 35172 Ig-164 44 rs749354699 0.3436 -0.656 0.999 N 0.605 0.489 0.582419091513 gnomAD-2.1.1 4.01E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
S/Y 35172 Ig-164 44 rs749354699 0.3436 -0.656 0.999 N 0.605 0.489 0.582419091513 gnomAD-4.0.0 1.59224E-06 None None None None N None 0 2.28645E-05 None 0 0 None 0 0 0 0 0
G/A 35463 Ig-166 44 rs373369136 0.1119 0.102 0.262 N 0.447 0.09 None gnomAD-2.1.1 1.89E-05 None None None None N None 8.37E-05 0 None 0 0 None 0 None 0 2.41E-05 0
G/A 35463 Ig-166 44 rs373369136 0.1119 0.102 0.262 N 0.447 0.09 None gnomAD-3.1.2 4.6E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 8.82E-05 0 0
G/A 35463 Ig-166 44 rs373369136 0.1119 0.102 0.262 N 0.447 0.09 None gnomAD-4.0.0 6.55598E-05 None None None None N None 2.69957E-05 0 None 0 0 None 0 0 8.58147E-05 0 3.22601E-05
G/R 35463 Ig-166 44 rs1474079403 0.2732 None 0.713 N 0.65 0.219 0.402471007487 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
G/R 35463 Ig-166 44 rs1474079403 0.2732 None 0.713 N 0.65 0.219 0.402471007487 gnomAD-4.0.0 1.06155E-05 None None None None N None 0 0 None 0 0 None 0 0 1.35957E-05 0 1.61296E-05
S/P 35648 Ig-167 42 None 0.8981 None 1.0 N 0.719 0.52 0.278968121808 gnomAD-4.0.0 2.05272E-06 None None None None N None 0 0 None 0 5.03931E-05 None 0 0 8.99493E-07 0 0
Q/H 35940 Ig-169 44 None 0.1614 None 0.927 N 0.285 0.128 0.119812018005 gnomAD-4.0.0 1.5909E-06 None None None -1.205(OBSL1) 0.247(OBSCN) N None 0 0 None 0 2.77269E-05 None 0 0 0 0 0
Q/R 35940 Ig-169 44 None 0.0799 None 0.002 N 0.22 0.135 0.0666544352282 gnomAD-4.0.0 1.20032E-06 None None None -2.032(OBSL1) -0.23(OBSCN) N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.