TITINdb

Map SAVs to Structure

Position	Domain position	SAV	Structural Position	RS	Q(SASA)	Disease	Source	MAF
19479	1	R/C	1	rs768666860	0.5250	None	gnomAD-2.1.1	4.15E-06
19479	1	R/C	1	rs768666860	0.5250	None	gnomAD-4.0.0	6.86725E-06
19479	1	R/H	1	rs2288569	0.5250	None	gnomAD-2.1.1	1.74251E-01
19479	1	R/H	1	rs2288569	0.5250	None	gnomAD-3.1.2	1.42208E-01
19479	1	R/H	1	rs2288569	0.5250	None	1000 genomes	2.1246E-01
19479	1	R/H	1	rs2288569	0.5250	None	gnomAD-4.0.0	1.53386E-01
19479	1	R/L	1	rs2288569	0.5250	None	gnomAD-2.1.1	4.1E-06
19479	1	R/L	1	rs2288569	0.5250	None	gnomAD-4.0.0	1.37171E-06
19480	2	P/S	2	None	0.1120	None	gnomAD-4.0.0	3.19982E-06
19482	4	P/L	4	rs746380279	0.4162	None	gnomAD-2.1.1	4.12E-06
19482	4	P/L	4	rs746380279	0.4162	None	gnomAD-4.0.0	2.05932E-06
19482	4	P/Q	4	None	0.4162	None	gnomAD-4.0.0	6.86439E-07
19482	4	P/S	4	rs758990147	0.4162	None	gnomAD-2.1.1	4.09E-06
19482	4	P/S	4	rs758990147	0.4162	None	gnomAD-3.1.2	1.32E-05
19482	4	P/S	4	rs758990147	0.4162	None	gnomAD-4.0.0	1.31728E-05
19483	5	P/A	5	rs367624056	0.1031	None	gnomAD-2.1.1	4.05E-06
19483	5	P/A	5	rs367624056	0.1031	None	gnomAD-3.1.2	6.59E-06
19483	5	P/A	5	rs367624056	0.1031	None	gnomAD-4.0.0	5.13346E-06
19483	5	P/R	5	rs1329556229	0.1031	None	gnomAD-2.1.1	4.05E-06
19483	5	P/R	5	rs1329556229	0.1031	None	gnomAD-4.0.0	4.78141E-06
19483	5	P/T	5	None	0.1031	None	gnomAD-2.1.1	4.05E-06
19483	5	P/T	5	None	0.1031	None	gnomAD-4.0.0	1.59386E-06
19485	7	G/R	7	None	0.4461	None	gnomAD-4.0.0	6.84572E-07
19486	8	P/L	8	None	0.8506	None	gnomAD-4.0.0	6.84566E-07
19486	8	P/R	8	None	0.8506	None	gnomAD-4.0.0	2.0537E-06
19489	11	F/L	12	rs1484820483	0.2810	None	gnomAD-3.1.2	1.31E-05
19489	11	F/L	12	rs1484820483	0.2810	None	gnomAD-4.0.0	3.71989E-06
19490	12	D/E	13	rs374118468	0.4822	None	gnomAD-2.1.1	8.1E-06
19490	12	D/E	13	rs374118468	0.4822	None	gnomAD-3.1.2	5.26E-05
19490	12	D/E	13	rs374118468	0.4822	None	gnomAD-4.0.0	4.10718E-06
19491	13	E/V	14	rs2050771375	0.3984	None	gnomAD-3.1.2	6.58E-06
19491	13	E/V	14	rs2050771375	0.3984	None	gnomAD-4.0.0	6.57851E-06
19492	14	V/G	15	rs2050770436	0.2200	None	gnomAD-3.1.2	6.58E-06
19492	14	V/G	15	rs2050770436	0.2200	None	gnomAD-4.0.0	6.57938E-06
19492	14	V/L	15	rs1224533828	0.2200	None	gnomAD-2.1.1	3.19E-05
19492	14	V/L	15	rs1224533828	0.2200	None	gnomAD-3.1.2	6.58E-06
19492	14	V/L	15	rs1224533828	0.2200	None	gnomAD-4.0.0	6.5786E-06
19492	14	V/M	15	None	0.2200	None	gnomAD-4.0.0	1.20032E-06
19494	16	K/R	17	None	0.3251	None	gnomAD-4.0.0	1.59297E-06
19496	18	Y/F	19	None	0.2380	None	gnomAD-4.0.0	1.20032E-06
19496	18	Y/S	19	None	0.2380	None	gnomAD-4.0.0	1.20032E-06
19497	19	M/I	20	rs752006805	0.0648	None	gnomAD-2.1.1	3.19E-05
19497	19	M/I	20	rs752006805	0.0648	None	gnomAD-4.0.0	2.5327E-05
19497	19	M/T	20	rs375365886	0.0648	None	gnomAD-2.1.1	8.09E-06
19497	19	M/T	20	rs375365886	0.0648	None	gnomAD-3.1.2	6.58E-06
19497	19	M/T	20	rs375365886	0.0648	None	gnomAD-4.0.0	1.30194E-05
19497	19	M/V	20	rs754532919	0.0648	None	gnomAD-2.1.1	1.21E-05
19497	19	M/V	20	rs754532919	0.0648	None	gnomAD-3.1.2	6.58E-06
19497	19	M/V	20	rs754532919	0.0648	None	gnomAD-4.0.0	6.41185E-06
19500	22	S/F	23	rs1465284889	0.1780	None	gnomAD-2.1.1	4.04E-06
19500	22	S/F	23	rs1465284889	0.1780	None	gnomAD-4.0.0	6.8451E-07
19503	25	P/A	26	rs762898731	0.4541	None	gnomAD-2.1.1	4.04E-06
19503	25	P/A	26	rs762898731	0.4541	None	gnomAD-4.0.0	1.59279E-06
19503	25	P/L	26	rs2050765996	0.4541	None	gnomAD-3.1.2	6.58E-06
19503	25	P/S	26	rs762898731	0.4541	None	gnomAD-2.1.1	4.04E-06
19503	25	P/S	26	rs762898731	0.4541	None	gnomAD-4.0.0	1.59279E-06
19504	26	P/L	27	rs1454300536	0.1611	None	gnomAD-2.1.1	4.04E-06
19504	26	P/L	27	rs1454300536	0.1611	None	gnomAD-4.0.0	6.84479E-07
19504	26	P/R	27	None	0.1611	None	gnomAD-4.0.0	6.84479E-07
19506	28	D/E	29	rs1238125586	0.6338	None	gnomAD-2.1.1	1.21E-05
19506	28	D/E	29	rs1238125586	0.6338	None	gnomAD-4.0.0	2.87473E-05
19506	28	D/G	29	None	0.6338	None	gnomAD-4.0.0	1.20037E-06
19507	29	D/V	30	rs1177368382	0.2645	None	gnomAD-2.1.1	4.04E-06
19508	30	G/E	31	None	0.3043	None	gnomAD-4.0.0	2.40065E-06
19509	31	G/S	32	rs1251770626	0.5876	None	gnomAD-2.1.1	4.04E-06
19509	31	G/S	32	rs1251770626	0.5876	None	gnomAD-4.0.0	1.59255E-06
19510	32	S/G	33	None	0.1856	None	gnomAD-4.0.0	1.59249E-06
19510	32	S/N	33	rs1209004438	0.1856	None	gnomAD-4.0.0	1.59249E-06
19512	34	I/T	35	rs1343150103	0.1902	None	gnomAD-2.1.1	4.04E-06
19512	34	I/T	35	rs1343150103	0.1902	None	gnomAD-4.0.0	1.59241E-06
19514	36	N/D	37	rs765019992	0.2562	None	gnomAD-2.1.1	8.07E-06
19514	36	N/D	37	rs765019992	0.2562	None	gnomAD-4.0.0	6.84408E-07
19514	36	N/H	37	None	0.2562	None	gnomAD-4.0.0	6.84408E-07
19514	36	N/S	37	rs761612554	0.2562	None	gnomAD-2.1.1	4.03E-06
19514	36	N/S	37	rs761612554	0.2562	None	gnomAD-4.0.0	2.05323E-06
19515	37	Y/C	38	rs1353143854	0.1073	None	gnomAD-2.1.1	4.03E-06
19515	37	Y/C	38	rs1353143854	0.1073	None	gnomAD-4.0.0	6.84406E-06
19516	38	I/V	39	rs776824040	0.2219	None	gnomAD-2.1.1	4.03E-06
19516	38	I/V	39	rs776824040	0.2219	None	gnomAD-4.0.0	1.59231E-06
19517	39	I/T	40	rs72646838	0.0728	None	gnomAD-2.1.1	4.03E-06
19517	39	I/T	40	rs72646838	0.0728	None	gnomAD-3.1.2	3.29E-05
19517	39	I/T	40	rs72646838	0.0728	ARVC	Literature	None
19517	39	I/T	40	rs72646838	0.0728	None	gnomAD-4.0.0	1.6116E-05
19518	40	E/D	41	rs747066203	0.1516	None	gnomAD-2.1.1	4.03E-06
19518	40	E/D	41	rs747066203	0.1516	None	gnomAD-4.0.0	6.84383E-07
19518	40	E/K	41	rs1329313961	0.1516	None	gnomAD-2.1.1	4.03E-06
19518	40	E/K	41	rs1329313961	0.1516	None	gnomAD-4.0.0	1.59227E-06
19519	41	K/E	42	rs775586810	0.1341	None	gnomAD-2.1.1	4.03E-06
19519	41	K/E	42	rs775586810	0.1341	None	gnomAD-4.0.0	1.59218E-06
19519	41	K/N	42	rs772071197	0.1341	None	gnomAD-2.1.1	4.03E-06
19519	41	K/N	42	rs772071197	0.1341	None	gnomAD-4.0.0	1.59223E-06
19521	43	E/D	44	rs1156295835	0.2196	None	gnomAD-2.1.1	8.06E-06
19521	43	E/D	44	rs1156295835	0.2196	None	gnomAD-4.0.0	3.18433E-06
19521	43	E/G	44	rs543122164	0.2196	None	gnomAD-2.1.1	4.03E-06
19521	43	E/G	44	rs543122164	0.2196	None	gnomAD-3.1.2	6.58E-06
19521	43	E/G	44	rs543122164	0.2196	None	1000 genomes	1.99681E-04
19521	43	E/G	44	rs543122164	0.2196	None	gnomAD-4.0.0	2.56333E-06
19521	43	E/K	44	rs746319976	0.2196	None	gnomAD-2.1.1	2.02E-05
19521	43	E/K	44	rs746319976	0.2196	None	gnomAD-3.1.2	1.32E-05
19521	43	E/K	44	rs746319976	0.2196	None	gnomAD-4.0.0	5.579E-06
19521	43	E/V	44	rs543122164	0.2196	None	gnomAD-2.1.1	4.03E-06
19526	48	V/F	64	rs377682563	0.7466	None	gnomAD-2.1.1	4.03E-06
19526	48	V/F	64	rs377682563	0.7466	None	gnomAD-4.0.0	6.84375E-07
19526	48	V/I	64	rs377682563	0.7466	None	gnomAD-2.1.1	1.43085E-04
19526	48	V/I	64	rs377682563	0.7466	None	gnomAD-3.1.2	1.90779E-04
19526	48	V/I	64	rs377682563	0.7466	None	1000 genomes	1.99681E-04
19526	48	V/I	64	rs377682563	0.7466	None	gnomAD-4.0.0	3.30376E-04
19528	50	M/T	66	None	0.3924	None	gnomAD-4.0.0	3.60097E-06
19529	51	P/S	67	None	0.6684	None	gnomAD-4.0.0	4.10625E-06
19529	51	P/T	67	rs878972430	0.6684	None	gnomAD-2.1.1	3.19E-05
19529	51	P/T	67	rs878972430	0.6684	None	gnomAD-3.1.2	2.63E-05
19529	51	P/T	67	rs878972430	0.6684	None	gnomAD-4.0.0	3.71945E-06
19530	52	V/A	68	rs1187285216	0.2773	None	gnomAD-2.1.1	4.03E-06
19530	52	V/A	68	rs1187285216	0.2773	None	gnomAD-4.0.0	3.18425E-06
19531	53	T/I	69	rs1258679826	0.2604	None	gnomAD-4.0.0	1.36873E-06
19531	53	T/R	69	rs1258679826	0.2604	None	gnomAD-2.1.1	4.03E-06
19531	53	T/R	69	rs1258679826	0.2604	None	gnomAD-4.0.0	6.84366E-07
19533	55	A/P	75	rs751194562	0.5640	None	gnomAD-2.1.1	4.03E-06
19533	55	A/P	75	rs751194562	0.5640	None	gnomAD-4.0.0	3.18433E-06
19534	56	S/G	77	None	0.1671	None	gnomAD-4.0.0	1.59211E-06
19534	56	S/N	77	rs563833549	0.1671	None	gnomAD-2.1.1	3.22E-05
19534	56	S/N	77	rs563833549	0.1671	None	gnomAD-3.1.2	3.29E-05
19534	56	S/N	77	rs563833549	0.1671	None	1000 genomes	1.99681E-04
19534	56	S/N	77	rs563833549	0.1671	None	gnomAD-4.0.0	1.67353E-05
19536	58	K/E	88	None	0.7674	None	gnomAD-4.0.0	3.18421E-06
19537	59	T/R	89	None	0.2245	None	gnomAD-4.0.0	6.84382E-07
19537	59	T/S	89	rs750320421	0.2245	None	gnomAD-2.1.1	4.03E-06
19537	59	T/S	89	rs750320421	0.2245	None	gnomAD-3.1.2	1.97E-05
19537	59	T/S	89	rs750320421	0.2245	None	gnomAD-4.0.0	5.12726E-06
19538	60	T/A	90	rs200017524	0.3787	None	gnomAD-2.1.1	4.54308E-04
19538	60	T/A	90	rs200017524	0.3787	None	gnomAD-3.1.2	1.40725E-03
19538	60	T/A	90	rs200017524	0.3787	None	1000 genomes	1.19808E-03
19538	60	T/A	90	rs200017524	0.3787	None	gnomAD-4.0.0	2.61564E-04
19538	60	T/I	90	rs370686112	0.3787	None	gnomAD-3.1.2	6.58E-06
19538	60	T/I	90	rs370686112	0.3787	None	gnomAD-4.0.0	6.57877E-06
19538	60	T/K	90	rs370686112	0.3787	None	gnomAD-2.1.1	3.22E-05
19538	60	T/K	90	rs370686112	0.3787	None	gnomAD-3.1.2	1.0526E-04
19538	60	T/K	90	rs370686112	0.3787	None	gnomAD-4.0.0	2.54157E-05
19539	61	C/F	91	rs539868284	0.1504	None	gnomAD-2.1.1	1.21E-05
19539	61	C/F	91	rs539868284	0.1504	None	gnomAD-3.1.2	6.58E-06
19539	61	C/F	91	rs539868284	0.1504	None	gnomAD-4.0.0	6.81905E-06
19539	61	C/R	91	rs753678261	0.1504	None	gnomAD-2.1.1	2.82E-05
19539	61	C/R	91	rs753678261	0.1504	None	gnomAD-3.1.2	1.97E-05
19539	61	C/R	91	rs753678261	0.1504	None	gnomAD-4.0.0	1.05377E-05
19539	61	C/S	91	rs753678261	0.1504	None	gnomAD-2.1.1	4.03E-06
19539	61	C/S	91	rs753678261	0.1504	None	gnomAD-4.0.0	1.36875E-06
19540	62	K/I	92	rs2050741869	0.3578	None	gnomAD-4.0.0	1.59229E-06
19541	63	V/A	93	rs760841948	0.1251	None	gnomAD-2.1.1	4.03E-06
19541	63	V/A	93	rs760841948	0.1251	None	gnomAD-4.0.0	1.59233E-06
19542	64	S/P	94	rs145198325	0.3906	None	gnomAD-2.1.1	2.42E-05
19542	64	S/P	94	rs145198325	0.3906	None	gnomAD-3.1.2	1.05213E-04
19542	64	S/P	94	rs145198325	0.3906	None	1000 genomes	1.99681E-04
19542	64	S/P	94	rs145198325	0.3906	None	gnomAD-4.0.0	1.98349E-05
19542	64	S/Y	94	None	0.3906	None	gnomAD-4.0.0	1.20032E-06
19543	65	K/E	96	None	0.8582	None	gnomAD-4.0.0	1.59232E-06
19544	66	L/P	97	rs373353480	0.1132	None	gnomAD-3.1.2	1.31E-05
19544	66	L/P	97	rs373353480	0.1132	None	gnomAD-4.0.0	8.97355E-06
19544	66	L/V	97	rs772132591	0.1132	None	gnomAD-2.1.1	4.03E-06
19544	66	L/V	97	rs772132591	0.1132	None	gnomAD-4.0.0	4.1066E-06
19546	68	E/Q	99	rs201840554	0.4781	None	gnomAD-2.1.1	9.91836E-04
19546	68	E/Q	99	rs201840554	0.4781	None	gnomAD-3.1.2	2.93355E-03
19546	68	E/Q	99	rs201840554	0.4781	None	1000 genomes	2.19649E-03
19546	68	E/Q	99	rs201840554	0.4781	None	gnomAD-4.0.0	5.47979E-04
19547	69	G/E	100	rs374713701	0.2984	None	gnomAD-2.1.1	8.07E-06
19547	69	G/E	100	rs374713701	0.2984	None	gnomAD-4.0.0	1.57427E-05
19547	69	G/R	100	rs886055260	0.2984	None	gnomAD-4.0.0	1.20032E-06
19547	69	G/V	100	rs374713701	0.2984	None	gnomAD-2.1.1	4.03E-06
19547	69	G/V	100	rs374713701	0.2984	None	gnomAD-3.1.2	2.63E-05
19547	69	G/V	100	rs374713701	0.2984	None	gnomAD-4.0.0	2.6303E-05
19549	71	D/Y	103	rs1472080899	0.2773	None	gnomAD-2.1.1	8.07E-06
19549	71	D/Y	103	rs1472080899	0.2773	None	gnomAD-3.1.2	6.58E-06
19549	71	D/Y	103	rs1472080899	0.2773	None	gnomAD-4.0.0	4.33978E-06
19550	72	Y/C	104	rs770314252	0.1103	None	gnomAD-2.1.1	7.17E-06
19550	72	Y/C	104	rs770314252	0.1103	None	gnomAD-3.1.2	6.57E-06
19550	72	Y/C	104	rs770314252	0.1103	None	gnomAD-4.0.0	1.17788E-05
19550	72	Y/D	104	None	0.1103	None	gnomAD-4.0.0	1.59279E-06
19550	72	Y/H	104	rs2154186587	0.1103	None	gnomAD-3.1.2	6.57E-06
19550	72	Y/H	104	rs2154186587	0.1103	None	gnomAD-4.0.0	2.56394E-06
19551	73	I/V	105	rs1264084790	0.1920	None	gnomAD-4.0.0	3.18563E-06
19553	75	R/G	107	None	0.1566	None	gnomAD-2.1.1	4.04E-06
19553	75	R/G	107	None	0.1566	None	gnomAD-3.1.2	6.58E-06
19553	75	R/G	107	None	0.1566	None	gnomAD-4.0.0	3.10014E-06
19553	75	R/P	107	None	0.1566	None	gnomAD-4.0.0	3.42273E-06
19553	75	R/Q	107	rs543279513	0.1566	None	gnomAD-2.1.1	1.08E-05
19553	75	R/Q	107	rs543279513	0.1566	None	gnomAD-3.1.2	1.97E-05
19553	75	R/Q	107	rs543279513	0.1566	None	1000 genomes	3.99361E-04
19553	75	R/Q	107	rs543279513	0.1566	None	gnomAD-4.0.0	7.43962E-06
19553	75	R/W	107	rs372959465	0.1566	None	gnomAD-2.1.1	1.43E-05
19553	75	R/W	107	rs372959465	0.1566	None	gnomAD-3.1.2	1.97E-05
19553	75	R/W	107	rs372959465	0.1566	None	gnomAD-4.0.0	1.30206E-05
19554	76	I/L	108	rs879139698	0.0577	None	gnomAD-4.0.0	2.40064E-06
19554	76	I/T	108	rs974431132	0.0577	None	gnomAD-2.1.1	4.04E-06
19554	76	I/T	108	rs974431132	0.0577	None	gnomAD-4.0.0	3.18593E-06
19555	77	H/R	109	None	0.1784	None	gnomAD-4.0.0	1.59301E-06
19555	77	H/Y	109	rs1289211242	0.1784	None	gnomAD-2.1.1	4.04E-06
19555	77	H/Y	109	rs1289211242	0.1784	None	gnomAD-4.0.0	6.84543E-06
19557	79	E/K	111	None	0.2705	None	gnomAD-4.0.0	2.40065E-06
19558	80	N/K	112	rs1455635388	0.0979	None	gnomAD-3.1.2	6.57E-06
19558	80	N/K	112	rs1455635388	0.0979	None	gnomAD-4.0.0	6.57445E-06
19558	80	N/S	112	rs369224233	0.0979	None	gnomAD-2.1.1	7.18E-06
19558	80	N/S	112	rs369224233	0.0979	None	gnomAD-3.1.2	1.31E-05
19558	80	N/S	112	rs369224233	0.0979	None	gnomAD-4.0.0	3.84724E-06
19559	81	L/M	113	None	0.7447	None	gnomAD-4.0.0	6.84595E-07
19559	81	L/Q	113	rs76604657	0.7447	None	gnomAD-2.1.1	1.43533E-04
19559	81	L/Q	113	rs76604657	0.7447	None	gnomAD-3.1.2	1.18315E-04
19559	81	L/Q	113	rs76604657	0.7447	None	1000 genomes	5.99042E-04
19559	81	L/Q	113	rs76604657	0.7447	None	gnomAD-4.0.0	1.76068E-04
19559	81	L/V	113	None	0.7447	None	gnomAD-4.0.0	6.84595E-07
19561	83	G/A	115	rs372491628	0.1993	None	gnomAD-2.1.1	4.05E-06
19561	83	G/A	115	rs372491628	0.1993	None	gnomAD-3.1.2	6.58E-06
19561	83	G/A	115	rs372491628	0.1993	None	gnomAD-4.0.0	4.34038E-06
19561	83	G/E	115	rs372491628	0.1993	None	gnomAD-2.1.1	4.05E-06
19561	83	G/R	115	rs760399687	0.1993	None	gnomAD-2.1.1	4.05E-06
19561	83	G/R	115	rs760399687	0.1993	None	gnomAD-3.1.2	6.58E-06
19561	83	G/R	115	rs760399687	0.1993	None	gnomAD-4.0.0	5.1307E-06
19562	84	I/L	117	rs397517637	0.4633	None	gnomAD-2.1.1	7.18E-06
19562	84	I/L	117	rs397517637	0.4633	None	gnomAD-3.1.2	6.57E-06
19562	84	I/L	117	rs397517637	0.4633	None	gnomAD-4.0.0	6.57272E-06
19562	84	I/R	117	None	0.4633	None	gnomAD-4.0.0	4.80129E-06
19562	84	I/V	117	rs397517637	0.4633	None	gnomAD-4.0.0	6.00164E-06
19563	85	S/N	118	rs759628569	0.0857	None	gnomAD-2.1.1	8.09E-06
19563	85	S/N	118	rs759628569	0.0857	None	gnomAD-3.1.2	1.97E-05
19563	85	S/N	118	rs759628569	0.0857	None	gnomAD-4.0.0	1.79818E-05
19564	86	D/E	119	rs1236959839	0.6103	None	gnomAD-2.1.1	3.19E-05
19564	86	D/E	119	rs1236959839	0.6103	None	gnomAD-3.1.2	6.57E-06
19564	86	D/E	119	rs1236959839	0.6103	None	gnomAD-4.0.0	6.08982E-06
19564	86	D/N	119	rs182400450	0.6103	None	gnomAD-2.1.1	4.05E-06
19564	86	D/N	119	rs182400450	0.6103	None	gnomAD-3.1.2	6.57E-06
19564	86	D/N	119	rs182400450	0.6103	None	1000 genomes	1.99681E-04
19564	86	D/N	119	rs182400450	0.6103	None	gnomAD-4.0.0	6.56961E-06
19564	86	D/Y	119	None	0.6103	None	gnomAD-4.0.0	3.18728E-06
19565	87	P/H	120	None	0.3359	None	gnomAD-4.0.0	2.40065E-06
19565	87	P/L	120	rs878880222	0.3359	None	gnomAD-2.1.1	3.19E-05
19565	87	P/L	120	rs878880222	0.3359	None	gnomAD-3.1.2	1.97E-05
19565	87	P/L	120	rs878880222	0.3359	None	gnomAD-4.0.0	1.97306E-05
19567	89	V/A	122	rs763514219	0.3777	None	gnomAD-2.1.1	4.05E-06
19567	89	V/A	122	rs763514219	0.3777	None	gnomAD-4.0.0	1.02704E-05
19567	89	V/L	122	None	0.3777	None	gnomAD-4.0.0	1.20032E-06
19567	89	V/M	122	rs1448926202	0.3777	None	gnomAD-2.1.1	3.19E-05
19567	89	V/M	122	rs1448926202	0.3777	None	gnomAD-3.1.2	1.32E-05
19567	89	V/M	122	rs1448926202	0.3777	None	gnomAD-4.0.0	1.31544E-05
19568	90	S/C	123	rs1465396608	0.1440	None	gnomAD-2.1.1	4.05E-06
19568	90	S/C	123	rs1465396608	0.1440	None	gnomAD-4.0.0	1.59417E-06
19569	91	D/N	125	rs397517638	0.9253	None	gnomAD-2.1.1	8.11E-06
19569	91	D/N	125	rs397517638	0.9253	None	gnomAD-3.1.2	6.58E-06
19569	91	D/N	125	rs397517638	0.9253	None	gnomAD-4.0.0	1.86072E-06
19571	93	M/V	127	rs770228515	0.1882	None	gnomAD-2.1.1	8.11E-06
19571	93	M/V	127	rs770228515	0.1882	None	gnomAD-4.0.0	8.90388E-06
19574	96	K/E	131	rs1032128606	0.6722	None	gnomAD-3.1.2	6.57E-06
19574	96	K/E	131	rs1032128606	0.6722	None	gnomAD-4.0.0	6.57376E-06
19575	97	D/Y	132	rs748522705	0.4854	None	gnomAD-2.1.1	4.07E-06
19575	97	D/Y	132	rs748522705	0.4854	None	gnomAD-4.0.0	1.5961E-06

Position	Domain position	SAV	RS	Q(SASA)	Source	Structural Position	Disease	AlphaMissense (IC)	AlphaMissense (N2AB)	CADD	Condel	DUET	FATHMM	M-CAP	mCSM	MetaLR	MetaSVM	MPC	MutationAssessor	MutationTaster	MutPred	MVP	PolyPhen-2	PrimateAI	PROVEAN	REVEL	Rhapsody	SIFT	Zygosity	Comments	MAF	AFR	AMR	AMS	ASJ	EAS	EUR	FIN	MDE	NFE	SAS	OTH	Site Annotation	Predicted PPI	mCSM-PPI
19479	1	R/C	rs768666860	0.5250	gnomAD-2.1.1	1	None	0.2446	0.2107	33.0	N	-0.549	0.92	0.011205	-0.337	0.3349	-0.4009	0.53609283062	3.02	1.0	0.358	0.575712373409	1.0	0.668404459953	-6.02	0.389	0.857	0.003	None	None	4.15E-06	0	0	0	0	None	3.54E-05	None	4.15E-06	0	0	0	None	I	None
19479	1	R/C	rs768666860	0.5250	gnomAD-4.0.0	1	None	0.2446	0.2107	33.0	N	-0.549	0.92	0.011205	-0.337	0.3349	-0.4009	0.53609283062	3.02	1.0	0.358	0.575712373409	1.0	0.668404459953	-6.02	0.389	0.857	0.003	None	None	6.86725E-06	0	0	0	0	None	0	6.95652E-04	6.86725E-06	2.70152E-06	3.5529E-05	0	None	I	None
19479	1	R/H	rs2288569	0.5250	gnomAD-2.1.1	1	None	0.2331	0.2259	None	N	-1.161	None	None	-1.068	None	None	None	None	None	None	None	1.0	None	None	0.463	0.784	None	None	None	1.74251E-01	7.19275E-02	1.49893E-01	1.73444E-01	4.31415E-01	None	2.65477E-01	None	1.74251E-01	1.51649E-01	1.457E-01	1.62504E-01	None	I	None
19479	1	R/H	rs2288569	0.5250	gnomAD-3.1.2	1	None	0.2331	0.2259	None	N	-1.161	None	None	-1.068	None	None	None	None	None	None	None	1.0	None	None	0.463	0.784	None	None	None	1.42208E-01	7.56783E-02	1.29391E-01	1.74754E-01	4.40946E-01	None	1.6331E-01	1.13924E-01	1.42208E-01	1.45641E-01	2.63213E-01	1.28955E-01	None	I	None
19479	1	R/H	rs2288569	0.5250	1000 genomes	1	None	0.2331	0.2259	None	N	-1.161	None	None	-1.068	None	None	None	None	None	None	None	1.0	None	None	0.463	0.784	None	None	None	2.1246E-01	6.66E-02	1.513E-01	None	4.544E-01	1.402E-01	None	None	2.1246E-01	None	2.781E-01	None	None	I	None
19479	1	R/H	rs2288569	0.5250	gnomAD-4.0.0	1	None	0.2331	0.2259	None	N	-1.161	None	None	-1.068	None	None	None	None	None	None	None	1.0	None	None	0.463	0.784	None	None	None	1.53386E-01	7.40343E-02	1.43709E-01	1.7421E-01	4.30079E-01	None	1.53113E-01	1.31779E-01	1.53386E-01	1.39271E-01	2.58419E-01	1.62847E-01	None	I	None
19479	1	R/L	rs2288569	0.5250	gnomAD-2.1.1	1	None	0.4755	0.4383	None	N	0.035	None	None	0.101	None	None	None	None	None	None	None	1.0	None	None	0.377	0.682	None	None	None	4.1E-06	0	0	0	0	None	0	None	4.1E-06	0	9.04E-06	0	None	I	None
19479	1	R/L	rs2288569	0.5250	gnomAD-4.0.0	1	None	0.4755	0.4383	None	N	0.035	None	None	0.101	None	None	None	None	None	None	None	1.0	None	None	0.377	0.682	None	None	None	1.37171E-06	0	0	0	0	None	0	0	1.37171E-06	1.80037E-06	0	0	None	I	None
19480	2	P/S	None	0.1120	gnomAD-4.0.0	2	None	0.9936	0.9927	28.1	D	None	0.43	0.039168	-2.194	0.5384	0.2941	0.464868906428	4.11	1.0	0.623	0.531531992086	1.0	0.66569507122	-6.13	0.479	0.769	0.008	None	None	3.19982E-06	0	4.64188E-05	0	0	None	0	0	3.19982E-06	0	0	0	None	N	None
19482	4	P/L	rs746380279	0.4162	gnomAD-2.1.1	4	None	0.1535	0.1532	32.0	N	-0.78	0.32	0.013044	-0.864	0.5284	0.1785	0.469182032742	3.985	1.0	0.535	0.710211490884	1.0	0.59451520443	-7.6	0.481	0.892	0.004	None	None	4.12E-06	0	0	0	0	None	0	None	4.12E-06	0	0	1.70184E-04	None	I	None
19482	4	P/L	rs746380279	0.4162	gnomAD-4.0.0	4	None	0.1535	0.1532	32.0	N	-0.78	0.32	0.013044	-0.864	0.5284	0.1785	0.469182032742	3.985	1.0	0.535	0.710211490884	1.0	0.59451520443	-7.6	0.481	0.892	0.004	None	None	2.05932E-06	0	0	0	0	None	0	0	2.05932E-06	2.701E-06	0	0	None	I	None
19482	4	P/Q	None	0.4162	gnomAD-4.0.0	4	None	0.2278	0.2642	31.0	N	None	0.29	0.008294	-1.18	0.4968	0.0499	0.450256649311	3.09	1.0	0.445	0.522344865107	1.0	0.538736701012	-6.13	0.465	0.883	0.009	None	None	6.86439E-07	0	0	0	0	None	0	0	6.86439E-07	9.00333E-07	0	0	None	I	None
19482	4	P/S	rs758990147	0.4162	gnomAD-2.1.1	4	None	0.2396	0.2873	26.9	N	-1.792	0.63	0.015516	-1.455	0.3838	-0.2446	0.466644225527	3.09	1.0	0.428	0.425148423609	1.0	0.533331096172	-6.07	0.433	0.886	0.005	None	None	4.09E-06	0	0	0	5.74E-05	None	0	None	4.09E-06	0	0	0	None	I	None
19482	4	P/S	rs758990147	0.4162	gnomAD-3.1.2	4	None	0.2396	0.2873	26.9	N	-1.792	0.63	0.015516	-1.455	0.3838	-0.2446	0.466644225527	3.09	1.0	0.428	0.425148423609	1.0	0.533331096172	-6.07	0.433	0.886	0.005	None	None	1.32E-05	0	0	0	3.87898E-04	None	0	0	1.32E-05	0	0	0	None	I	None
19482	4	P/S	rs758990147	0.4162	gnomAD-4.0.0	4	None	0.2396	0.2873	26.9	N	-1.792	0.63	0.015516	-1.455	0.3838	-0.2446	0.466644225527	3.09	1.0	0.428	0.425148423609	1.0	0.533331096172	-6.07	0.433	0.886	0.005	None	None	1.31728E-05	0	0	0	3.87898E-04	None	0	0	1.31728E-05	0	0	0	None	I	None
19483	5	P/A	rs367624056	0.1031	gnomAD-2.1.1	5	None	0.6104	0.5426	None	N	-2.594	None	None	-2.251	None	None	None	None	None	None	None	1.0	None	None	0.404	0.82	None	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.97E-06	0	None	N	None
19483	5	P/A	rs367624056	0.1031	gnomAD-3.1.2	5	None	0.6104	0.5426	None	N	-2.594	None	None	-2.251	None	None	None	None	None	None	None	1.0	None	None	0.404	0.82	None	None	None	6.59E-06	0	0	0	0	None	0	0	6.59E-06	1.47E-05	0	0	None	N	None
19483	5	P/A	rs367624056	0.1031	gnomAD-4.0.0	5	None	0.6104	0.5426	None	N	-2.594	None	None	-2.251	None	None	None	None	None	None	None	1.0	None	None	0.404	0.82	None	None	None	5.13346E-06	0	0	0	0	None	0	0	5.13346E-06	9.57992E-06	0	0	None	N	None
19483	5	P/R	rs1329556229	0.1031	gnomAD-2.1.1	5	None	0.9939	0.9925	32.0	D	-1.877	0.29	0.017144	-1.796	0.5804	0.392	0.4773412541	4.275	1.0	0.778	0.58934274002	1.0	0.633861660957	-6.9	0.58	0.949	0.003	None	None	4.05E-06	0	0	0	0	None	3.29E-05	None	4.05E-06	0	0	0	None	N	None
19483	5	P/R	rs1329556229	0.1031	gnomAD-4.0.0	5	None	0.9939	0.9925	32.0	D	-1.877	0.29	0.017144	-1.796	0.5804	0.392	0.4773412541	4.275	1.0	0.778	0.58934274002	1.0	0.633861660957	-6.9	0.58	0.949	0.003	None	None	4.78141E-06	0	0	0	0	None	0	0	4.78141E-06	0	4.3101E-05	0	None	N	None
19483	5	P/T	None	0.1031	gnomAD-2.1.1	5	None	0.8622	0.8248	26.7	D	-2.682	0.26	0.009891	-2.544	0.5804	0.392	0.48919594472	3.93	1.0	0.721	0.565722134273	1.0	0.595853388309	-6.13	0.547	0.885	0.012	None	None	4.05E-06	0	2.92E-05	0	0	None	0	None	4.05E-06	0	0	0	None	N	None
19483	5	P/T	None	0.1031	gnomAD-4.0.0	5	None	0.8622	0.8248	26.7	D	-2.682	0.26	0.009891	-2.544	0.5804	0.392	0.48919594472	3.93	1.0	0.721	0.565722134273	1.0	0.595853388309	-6.13	0.547	0.885	0.012	None	None	1.59386E-06	0	2.29284E-05	0	0	None	0	0	1.59386E-06	0	0	0	None	N	None
19485	7	G/R	None	0.4461	gnomAD-4.0.0	7	None	0.9799	0.9815	26.6	N	None	0.87	0.017727	-0.582	0.3126	-0.4709	0.506463245118	2.655	1.0	0.436	0.3571064206	1.0	0.783180773258	-5.63	0.472	0.743	0.162	None	None	6.84572E-07	0	0	0	0	None	0	0	6.84572E-07	8.99658E-07	0	0	None	N	None
19486	8	P/L	None	0.8506	gnomAD-4.0.0	8	None	0.4363	0.4718	32.0	N	None	0.6	0.00946	-0.26	0.4086	-0.2201	0.469182032742	3.505	1.0	0.503	0.517876074734	1.0	0.68390917778	-7.3	0.469	0.911	0.005	None	None	6.84566E-07	0	0	0	0	None	0	0	6.84566E-07	0	0	1.65766E-05	None	N	None
19486	8	P/R	None	0.8506	gnomAD-4.0.0	8	None	0.5668	0.5939	31.0	N	None	0.34	0.009242	0.041	0.3985	-0.2587	0.4773412541	3.36	1.0	0.483	0.569878715874	1.0	0.679160773754	-6.57	0.521	0.922	0.06	None	None	2.0537E-06	0	0	0	0	None	0	0	2.0537E-06	2.69894E-06	0	0	None	N	None
19489	11	F/L	rs1484820483	0.2810	gnomAD-3.1.2	12	None	0.9491	0.9416	26.0	N	-1.323	0.41	0.020462	-1.391	0.1853	-0.7297	0.496083062219	1.42	0.999757	0.503	0.398283496042	0.999	0.706959187984	-4.33	0.448	0.571	0.234	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	2.94E-05	0	0	None	N	None
19489	11	F/L	rs1484820483	0.2810	gnomAD-4.0.0	12	None	0.9491	0.9416	26.0	N	-1.323	0.41	0.020462	-1.391	0.1853	-0.7297	0.496083062219	1.42	0.999757	0.503	0.398283496042	0.999	0.706959187984	-4.33	0.448	0.571	0.234	None	None	3.71989E-06	0	0	0	0	None	0	0	3.71989E-06	4.23876E-06	0	1.6022E-05	None	N	None
19490	12	D/E	rs374118468	0.4822	gnomAD-2.1.1	13	None	0.1179	0.1309	26.2	N	-0.225	0.49	0.02234	-0.346	0.1888	-0.8245	0.391569321929	0.51	0.990853	0.349	0.257786959452	0.996	0.49250382185	-2.4	0.143	0.402	0.41	None	None	8.1E-06	0	2.91E-05	0	0	None	0	None	8.1E-06	0	8.97E-06	0	None	N	None
19490	12	D/E	rs374118468	0.4822	gnomAD-3.1.2	13	None	0.1179	0.1309	26.2	N	-0.225	0.49	0.02234	-0.346	0.1888	-0.8245	0.391569321929	0.51	0.990853	0.349	0.257786959452	0.996	0.49250382185	-2.4	0.143	0.402	0.41	None	None	5.26E-05	4.83E-05	6.55E-05	0	3.87747E-04	None	0	0	5.26E-05	0	4.13736E-04	4.78469E-04	None	N	None
19490	12	D/E	rs374118468	0.4822	gnomAD-4.0.0	13	None	0.1179	0.1309	26.2	N	-0.225	0.49	0.02234	-0.346	0.1888	-0.8245	0.391569321929	0.51	0.990853	0.349	0.257786959452	0.996	0.49250382185	-2.4	0.143	0.402	0.41	None	None	4.10718E-06	0	2.24034E-05	0	0	None	0	0	4.10718E-06	4.49811E-06	0	0	None	N	None
19491	13	E/V	rs2050771375	0.3984	gnomAD-3.1.2	14	None	0.3994	0.4075	34.0	N	None	0.31	0.034152	-0.066	0.4624	0.0455	0.500354548257	2.98	1.0	0.531	0.556695477184	1.0	0.534637987614	-5.3	0.603	0.7	0.041	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	0	4.78469E-04	None	N	None
19491	13	E/V	rs2050771375	0.3984	gnomAD-4.0.0	14	None	0.3994	0.4075	34.0	N	None	0.31	0.034152	-0.066	0.4624	0.0455	0.500354548257	2.98	1.0	0.531	0.556695477184	1.0	0.534637987614	-5.3	0.603	0.7	0.041	None	None	6.57851E-06	0	0	0	0	None	0	0	6.57851E-06	0	0	4.78469E-04	None	N	None
19492	14	V/G	rs2050770436	0.2200	gnomAD-3.1.2	15	None	0.6358	0.6436	31.0	N	None	0.19	0.04809	-1.807	0.4456	-0.0081	0.517821669362	3.2	1.0	0.606	0.7700109816	1.0	0.57960498333	-5.37	0.513	0.847	0.001	None	None	6.58E-06	2.42E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
19492	14	V/G	rs2050770436	0.2200	gnomAD-4.0.0	15	None	0.6358	0.6436	31.0	N	None	0.19	0.04809	-1.807	0.4456	-0.0081	0.517821669362	3.2	1.0	0.606	0.7700109816	1.0	0.57960498333	-5.37	0.513	0.847	0.001	None	None	6.57938E-06	2.41581E-05	0	0	0	None	0	0	6.57938E-06	0	0	0	None	N	None
19492	14	V/L	rs1224533828	0.2200	gnomAD-2.1.1	15	None	0.4656	0.4585	26.2	N	-0.7	0.3	0.023439	-0.617	0.2299	-0.6759	0.27893692603	2.015	0.999996	0.548	0.430126000877	0.962	0.650803804398	-2.17	0.274	0.387	0.012	None	None	3.19E-05	1.14758E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	None
19492	14	V/L	rs1224533828	0.2200	gnomAD-3.1.2	15	None	0.4656	0.4585	26.2	N	-0.7	0.3	0.023439	-0.617	0.2299	-0.6759	0.27893692603	2.015	0.999996	0.548	0.430126000877	0.962	0.650803804398	-2.17	0.274	0.387	0.012	None	None	6.58E-06	2.42E-05	0	0	0	None	0	0	6.58E-06	0	0	0	None	N	None
19492	14	V/L	rs1224533828	0.2200	gnomAD-4.0.0	15	None	0.4656	0.4585	26.2	N	-0.7	0.3	0.023439	-0.617	0.2299	-0.6759	0.27893692603	2.015	0.999996	0.548	0.430126000877	0.962	0.650803804398	-2.17	0.274	0.387	0.012	None	None	6.5786E-06	2.41558E-05	0	0	0	None	0	0	6.5786E-06	0	0	0	None	N	None
19492	14	V/M	None	0.2200	gnomAD-4.0.0	15	None	0.3069	0.3122	28.0	N	None	0.21	0.015213	-0.477	0.4174	-0.234	0.451439691398	2.465	0.999996	0.558	0.502568190621	0.999	0.673651099205	-2.23	0.382	0.709	0.051	None	None	1.20032E-06	0	0	0	0	None	0	6.17284E-04	1.20032E-06	0	0	0	None	N	None
19494	16	K/R	None	0.3251	gnomAD-4.0.0	17	None	0.0675	0.0756	25.8	N	None	0.41	0.019194	-0.397	0.1062	-1.0025	0.0707425195306	0.415	0.957958	0.485	0.273070737957	0.011	0.390016138554	-1.2	0.08	0.105	0.675	None	None	1.59297E-06	0	0	0	0	None	0	0	1.59297E-06	2.85976E-06	0	0	None	N	None
19496	18	Y/F	None	0.2380	gnomAD-4.0.0	19	None	0.0724	0.0742	26.3	N	None	0.4	0.036021	-1.159	0.1144	-0.9012	0.0770561423283	0.955	0.738889	0.48	0.293147016451	None	0.36212182045	-2.8	0.126	0.131	0.22	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
19496	18	Y/S	None	0.2380	gnomAD-4.0.0	19	None	0.0642	0.0716	27.8	N	None	0.88	0.022826	-2.105	0.0408	-0.9709	0.143490453161	-1.005	0.972351	0.516	0.442567846599	0.117	0.362459242344	-5.6	0.253	0.513	0.479	None	None	1.20032E-06	6.33473E-05	0	0	0	None	0	0	1.20032E-06	0	0	0	None	N	None
19497	19	M/I	rs752006805	0.0648	gnomAD-2.1.1	20	None	0.4464	0.415	24.3	N	0.394	0.57	0.015294	-0.127	0.0871	-1.0215	0.0942643627443	-0.08	0.999797	0.523	0.464528537357	0.006	0.52009344101	-2.53	0.163	0.329	0.31	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.49E-05	0	None	N	None
19497	19	M/I	rs752006805	0.0648	gnomAD-4.0.0	20	None	0.4464	0.415	24.3	N	0.394	0.57	0.015294	-0.127	0.0871	-1.0215	0.0942643627443	-0.08	0.999797	0.523	0.464528537357	0.006	0.52009344101	-2.53	0.163	0.329	0.31	None	None	2.5327E-05	0	0	0	0	None	0	0	2.5327E-05	2.87876E-05	0	8.2872E-05	None	N	None
19497	19	M/T	rs375365886	0.0648	gnomAD-2.1.1	20	None	0.6633	0.6038	None	D	-1.318	None	None	-1.64	None	None	None	None	None	None	None	0.492	None	None	0.397	0.767	None	None	None	8.09E-06	0	0	0	0	None	3.27E-05	None	8.09E-06	0	8.96E-06	0	None	N	None
19497	19	M/T	rs375365886	0.0648	gnomAD-3.1.2	20	None	0.6633	0.6038	None	D	-1.318	None	None	-1.64	None	None	None	None	None	None	None	0.492	None	None	0.397	0.767	None	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
19497	19	M/T	rs375365886	0.0648	gnomAD-4.0.0	20	None	0.6633	0.6038	None	D	-1.318	None	None	-1.64	None	None	None	None	None	None	None	0.492	None	None	0.397	0.767	None	None	None	1.30194E-05	1.3354E-05	1.669E-05	0	0	None	0	0	1.30194E-05	1.27162E-05	1.0983E-05	4.80677E-05	None	N	None
19497	19	M/V	rs754532919	0.0648	gnomAD-2.1.1	20	None	0.1046	0.0925	24.4	N	-0.13	0.64	0.024665	-0.601	0.0553	-1.0501	0.0924982757339	0.235	0.999599	0.561	0.43046518545	0.041	0.472535312176	-2.5	0.17	0.431	0.735	None	None	1.21E-05	0	0	0	0	None	6.54E-05	None	1.21E-05	0	8.96E-06	0	None	N	None
19497	19	M/V	rs754532919	0.0648	gnomAD-3.1.2	20	None	0.1046	0.0925	24.4	N	-0.13	0.64	0.024665	-0.601	0.0553	-1.0501	0.0924982757339	0.235	0.999599	0.561	0.43046518545	0.041	0.472535312176	-2.5	0.17	0.431	0.735	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
19497	19	M/V	rs754532919	0.0648	gnomAD-4.0.0	20	None	0.1046	0.0925	24.4	N	-0.13	0.64	0.024665	-0.601	0.0553	-1.0501	0.0924982757339	0.235	0.999599	0.561	0.43046518545	0.041	0.472535312176	-2.5	0.17	0.431	0.735	None	None	6.41185E-06	0	0	0	0	None	0	0	6.41185E-06	2.3942E-06	5.36222E-05	0	None	N	None
19500	22	S/F	rs1465284889	0.1780	gnomAD-2.1.1	23	None	0.452	0.429	35.0	D	-0.659	0.08	0.019122	-0.901	0.5598	0.3077	0.484728417222	3.865	1.0	0.528	0.741150988799	1.0	0.641292333603	-4.53	0.495	0.9	0.001	None	None	4.04E-06	0	2.91E-05	0	0	None	0	None	4.04E-06	0	0	0	None	N	None
19500	22	S/F	rs1465284889	0.1780	gnomAD-4.0.0	23	None	0.452	0.429	35.0	D	-0.659	0.08	0.019122	-0.901	0.5598	0.3077	0.484728417222	3.865	1.0	0.528	0.741150988799	1.0	0.641292333603	-4.53	0.495	0.9	0.001	None	None	6.8451E-07	0	2.23994E-05	0	0	None	0	0	6.8451E-07	0	0	0	None	N	None
19503	25	P/A	rs762898731	0.4541	gnomAD-2.1.1	26	None	0.1022	0.0985	25.9	N	-1.684	0.24	0.009069	-1.658	0.3441	-0.4352	0.457628982806	2.135	1.0	0.57	0.364342057095	1.0	0.523396492004	-5.83	0.385	0.823	0.011	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.95E-06	0	None	N	None
19503	25	P/A	rs762898731	0.4541	gnomAD-4.0.0	26	None	0.1022	0.0985	25.9	N	-1.684	0.24	0.009069	-1.658	0.3441	-0.4352	0.457628982806	2.135	1.0	0.57	0.364342057095	1.0	0.523396492004	-5.83	0.385	0.823	0.011	None	None	1.59279E-06	0	0	0	0	None	0	0	1.59279E-06	2.85961E-06	0	0	None	N	None
19503	25	P/L	rs2050765996	0.4541	gnomAD-3.1.2	26	None	0.1621	0.1519	32.0	N	None	0.1	0.02598	-0.701	0.4863	0.008	0.469182032742	3.395	1.0	0.593	0.717771820488	1.0	0.606214880943	-7.33	0.496	0.885	0.01	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
19503	25	P/S	rs762898731	0.4541	gnomAD-2.1.1	26	None	0.2291	0.2328	26.8	N	-2.14	0.12	0.014997	-1.944	0.4443	-0.1505	0.466644225527	2.36	1.0	0.542	0.415438038341	1.0	0.53540623188	-5.8	0.442	0.858	0.011	None	None	4.04E-06	0	0	0	5.65E-05	None	0	None	4.04E-06	0	0	0	None	N	None
19503	25	P/S	rs762898731	0.4541	gnomAD-4.0.0	26	None	0.2291	0.2328	26.8	N	-2.14	0.12	0.014997	-1.944	0.4443	-0.1505	0.466644225527	2.36	1.0	0.542	0.415438038341	1.0	0.53540623188	-5.8	0.442	0.858	0.011	None	None	1.59279E-06	0	0	0	2.79049E-05	None	0	0	1.59279E-06	0	0	0	None	N	None
19504	26	P/L	rs1454300536	0.1611	gnomAD-2.1.1	27	None	0.951	0.9495	32.0	D	-0.755	-0.83	0.014894	-0.716	0.7213	0.6102	0.469182032742	3.93	1.0	0.781	0.805501000142	1.0	0.669958233833	-7.67	0.616	0.892	0.002	None	None	4.04E-06	0	2.91E-05	0	0	None	0	None	4.04E-06	0	0	0	None	N	None
19504	26	P/L	rs1454300536	0.1611	gnomAD-4.0.0	27	None	0.951	0.9495	32.0	D	-0.755	-0.83	0.014894	-0.716	0.7213	0.6102	0.469182032742	3.93	1.0	0.781	0.805501000142	1.0	0.669958233833	-7.67	0.616	0.892	0.002	None	None	6.84479E-07	0	2.23964E-05	0	0	None	0	0	6.84479E-07	0	0	0	None	N	None
19504	26	P/R	None	0.1611	gnomAD-4.0.0	27	None	0.992	0.9904	32.0	D	None	-0.87	0.017596	-1.239	0.704	0.543	0.4773412541	3.93	1.0	0.772	0.678699861113	1.0	0.664010941982	-6.9	0.635	0.882	0.003	None	None	6.84479E-07	0	0	0	0	None	0	0	6.84479E-07	8.99591E-07	0	0	None	N	None
19506	28	D/E	rs1238125586	0.6338	gnomAD-2.1.1	29	None	0.5357	0.5661	25.7	N	-0.021	0.64	0.011187	-0.248	0.3035	-0.4208	0.450463449177	2.465	0.998155	0.464	0.351830644314	1.0	0.636876404285	-3.07	0.334	0.403	0.086	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.68E-05	0	None	I	None
19506	28	D/E	rs1238125586	0.6338	gnomAD-4.0.0	29	None	0.5357	0.5661	25.7	N	-0.021	0.64	0.011187	-0.248	0.3035	-0.4208	0.450463449177	2.465	0.998155	0.464	0.351830644314	1.0	0.636876404285	-3.07	0.334	0.403	0.086	None	None	2.87473E-05	0	0	0	0	None	0	0	2.87473E-05	3.7783E-05	0	0	None	I	None
19506	28	D/G	None	0.6338	gnomAD-4.0.0	29	None	0.7332	0.7064	32.0	N	None	0.54	0.018298	-0.431	0.4471	0.0712	0.528847580626	3.32	1.0	0.481	0.411265580357	1.0	0.619786977768	-5.37	0.542	0.72	0.008	None	None	1.20037E-06	0	0	0	0	None	0	0	1.20037E-06	1.31255E-06	0	0	None	I	None
19507	29	D/V	rs1177368382	0.2645	gnomAD-2.1.1	30	None	0.8229	0.8554	29.3	N	0.205	0.32	0.038626	0.109	0.4551	0.0519	0.51541283519	3.25	1.0	0.516	0.515882253919	0.989	0.476135551929	-6.67	0.485	0.696	0.002	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.93E-06	0	None	I	None
19508	30	G/E	None	0.3043	gnomAD-4.0.0	31	None	0.9953	0.9956	27.1	D	None	0.44	0.019383	-0.496	0.5445	0.3462	0.526218639335	3.61	1.0	0.728	0.541466613703	1.0	0.695421814919	-6.13	0.624	0.852	0.005	None	None	2.40065E-06	0	0	0	0	None	0	0	2.40065E-06	2.62501E-06	0	0	None	I	None
19509	31	G/S	rs1251770626	0.5876	gnomAD-2.1.1	32	None	0.6213	0.6909	25.3	N	-0.345	-0.1	0.01423	-0.324	0.5122	0.0327	0.463496485926	2.99	1.0	0.446	0.4018988957	1.0	0.555840015411	-4.6	0.472	0.695	0.009	None	None	4.04E-06	0	0	0	0	None	3.27E-05	None	4.04E-06	0	0	0	None	I	None
19509	31	G/S	rs1251770626	0.5876	gnomAD-4.0.0	32	None	0.6213	0.6909	25.3	N	-0.345	-0.1	0.01423	-0.324	0.5122	0.0327	0.463496485926	2.99	1.0	0.446	0.4018988957	1.0	0.555840015411	-4.6	0.472	0.695	0.009	None	None	1.59255E-06	0	0	0	0	None	0	0	1.59255E-06	0	1.43316E-05	0	None	I	None
19510	32	S/G	None	0.1856	gnomAD-4.0.0	33	None	0.1886	0.1819	23.3	N	None	0.61	0.046599	-1.14	0.1956	-0.6789	0.184971320754	2.88	0.98758	0.43	0.222439326576	0.704	0.448808521032	-2.77	0.156	0.545	0.018	None	None	1.59249E-06	0	0	0	0	None	0	0	1.59249E-06	0	0	3.02608E-05	None	I	None
19510	32	S/N	rs1209004438	0.1856	gnomAD-4.0.0	33	None	0.3886	0.4305	24.4	N	None	0.3	0.024647	-0.72	0.4059	-0.1999	0.343141758443	2.755	0.997512	0.434	0.307966526162	0.986	0.516009092331	-2.23	0.339	0.65	0.007	None	None	1.59249E-06	0	0	0	0	None	0	0	1.59249E-06	2.85943E-06	0	0	None	I	None
19512	34	I/T	rs1343150103	0.1902	gnomAD-2.1.1	35	None	0.9518	0.9386	27.0	D	-2.227	0.03	0.023913	-1.866	0.4585	0.1014	0.331718741098	3.7	0.999966	0.691	0.768437955185	0.822	0.73973274231	-3.63	0.545	0.807	0.002	None	None	4.04E-06	0	2.91E-05	0	0	None	0	None	4.04E-06	0	0	0	None	I	None
19512	34	I/T	rs1343150103	0.1902	gnomAD-4.0.0	35	None	0.9518	0.9386	27.0	D	-2.227	0.03	0.023913	-1.866	0.4585	0.1014	0.331718741098	3.7	0.999966	0.691	0.768437955185	0.822	0.73973274231	-3.63	0.545	0.807	0.002	None	None	1.59241E-06	0	2.28959E-05	0	0	None	0	0	1.59241E-06	0	0	0	None	I	None
19514	36	N/D	rs765019992	0.2562	gnomAD-2.1.1	37	None	0.6571	0.6991	25.3	N	-1.593	0.4	0.024692	-0.991	0.2888	-0.4215	0.319658233137	3.095	0.999981	0.643	0.338110398507	0.892	0.636321902275	-3.83	0.468	0.467	0.039	None	None	8.07E-06	0	0	0	1.12511E-04	None	0	None	8.07E-06	0	0	0	None	N	None
19514	36	N/D	rs765019992	0.2562	gnomAD-4.0.0	37	None	0.6571	0.6991	25.3	N	-1.593	0.4	0.024692	-0.991	0.2888	-0.4215	0.319658233137	3.095	0.999981	0.643	0.338110398507	0.892	0.636321902275	-3.83	0.468	0.467	0.039	None	None	6.84408E-07	0	0	0	2.52921E-05	None	0	0	6.84408E-07	0	0	0	None	N	None
19514	36	N/H	None	0.2562	gnomAD-4.0.0	37	None	0.3616	0.3552	25.5	D	None	0.4	0.018535	-1.112	0.3149	-0.4299	0.44369051695	1.825	0.999991	0.574	0.349870743963	0.994	0.598105192184	-3.83	0.45	0.522	0.041	None	None	6.84408E-07	0	0	0	0	None	0	0	6.84408E-07	8.99578E-07	0	0	None	N	None
19514	36	N/S	rs761612554	0.2562	gnomAD-2.1.1	37	None	0.1627	0.1533	25.5	N	-0.97	0.48	0.020629	-0.959	0.1635	-0.8184	0.167897587978	1.62	0.999721	0.492	0.188950314367	0.805	0.531452059746	-3.83	0.235	0.493	0.107	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
19514	36	N/S	rs761612554	0.2562	gnomAD-4.0.0	37	None	0.1627	0.1533	25.5	N	-0.97	0.48	0.020629	-0.959	0.1635	-0.8184	0.167897587978	1.62	0.999721	0.492	0.188950314367	0.805	0.531452059746	-3.83	0.235	0.493	0.107	None	None	2.05323E-06	0	0	0	0	None	0	0	2.05323E-06	2.69873E-06	0	0	None	N	None
19515	37	Y/C	rs1353143854	0.1073	gnomAD-2.1.1	38	None	0.9406	0.9212	32.0	D	-2.003	-1.48	0.0802	-2.27	0.7885	0.8467	0.517459491388	4.31	1.0	0.816	0.87881004843	1.0	0.774373292923	-6.9	0.919	0.858	0.001	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
19515	37	Y/C	rs1353143854	0.1073	gnomAD-4.0.0	38	None	0.9406	0.9212	32.0	D	-2.003	-1.48	0.0802	-2.27	0.7885	0.8467	0.517459491388	4.31	1.0	0.816	0.87881004843	1.0	0.774373292923	-6.9	0.919	0.858	0.001	None	None	6.84406E-06	0	0	0	0	None	0	0	6.84406E-06	8.99577E-06	0	0	None	N	None
19516	38	I/V	rs776824040	0.2219	gnomAD-2.1.1	39	None	0.114	0.0974	23.4	N	-1.754	0.46	0.014412	-1.623	0.1442	-0.8598	0.0943034016203	0.605	0.999886	0.352	0.426084969639	0.333	0.510870218277	-0.63	0.105	0.267	0.425	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	I	None
19516	38	I/V	rs776824040	0.2219	gnomAD-4.0.0	39	None	0.114	0.0974	23.4	N	-1.754	0.46	0.014412	-1.623	0.1442	-0.8598	0.0943034016203	0.605	0.999886	0.352	0.426084969639	0.333	0.510870218277	-0.63	0.105	0.267	0.425	None	None	1.59231E-06	0	0	0	0	None	0	0	1.59231E-06	2.85932E-06	0	0	None	I	None
19517	39	I/T	rs72646838	0.0728	gnomAD-2.1.1	40	None	0.715	0.6856	None	D	-3.215	None	None	-3.196	None	None	None	None	None	None	None	0.201	None	None	0.515	0.669	None	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
19517	39	I/T	rs72646838	0.0728	gnomAD-3.1.2	40	None	0.715	0.6856	None	D	-3.215	None	None	-3.196	None	None	None	None	None	None	None	0.201	None	None	0.515	0.669	None	None	None	3.29E-05	0	0	0	0	None	0	9.49367E-03	3.29E-05	1.47E-05	0	4.78927E-04	None	N	None
19517	39	I/T	rs72646838	0.0728	http://www.ncbi.nlm.nih.gov/pubmed/21810661;	40	ARVC;	0.715	0.6856	None	D	-3.215	None	None	-3.196	None	None	None	None	None	None	None	0.201	None	None	0.515	0.669	None	het	Genetic analysis of TTN in 38 ARVC families, incomplete penetrance	None	None	None	None	None	None	None	None	None	None	None	None	None	N	None
19517	39	I/T	rs72646838	0.0728	gnomAD-4.0.0	40	None	0.715	0.6856	None	D	-3.215	None	None	-3.196	None	None	None	None	None	None	None	0.201	None	None	0.515	0.669	None	None	None	1.6116E-05	0	1.66817E-05	0	0	None	0	9.90753E-04	1.6116E-05	1.52591E-05	0	1.60113E-05	None	N	None
19518	40	E/D	rs747066203	0.1516	gnomAD-2.1.1	41	None	0.6911	0.6494	24.3	N	-2.09	0.32	0.013163	-1.691	0.385	-0.2548	0.442122350618	2.225	0.999936	0.484	0.295974979623	0.999	0.572602629662	-2.3	0.345	0.649	0.013	None	None	4.03E-06	0	0	0	5.62E-05	None	0	None	4.03E-06	0	0	0	None	N	None
19518	40	E/D	rs747066203	0.1516	gnomAD-4.0.0	41	None	0.6911	0.6494	24.3	N	-2.09	0.32	0.013163	-1.691	0.385	-0.2548	0.442122350618	2.225	0.999936	0.484	0.295974979623	0.999	0.572602629662	-2.3	0.345	0.649	0.013	None	None	6.84383E-07	0	0	0	2.52755E-05	None	0	0	6.84383E-07	0	0	0	None	N	None
19518	40	E/K	rs1329313961	0.1516	gnomAD-2.1.1	41	None	0.854	0.8072	28.4	N	-2.384	0.38	0.009681	-1.591	0.4814	0.0796	0.489131336793	3.45	1.0	0.649	0.489243007833	0.999	0.648198604584	-3.07	0.377	0.686	0.006	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
19518	40	E/K	rs1329313961	0.1516	gnomAD-4.0.0	41	None	0.854	0.8072	28.4	N	-2.384	0.38	0.009681	-1.591	0.4814	0.0796	0.489131336793	3.45	1.0	0.649	0.489243007833	0.999	0.648198604584	-3.07	0.377	0.686	0.006	None	None	1.59227E-06	0	0	0	0	None	0	0	1.59227E-06	0	1.43308E-05	0	None	N	None
19519	41	K/E	rs775586810	0.1341	gnomAD-2.1.1	42	None	0.9054	0.8861	29.3	N	-2.557	0.38	0.015381	-1.958	0.4367	0.0268	0.543662385431	3.235	0.999999	0.62	0.440604514059	0.999	0.598856925964	-3.07	0.457	0.712	0.004	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.92E-06	0	None	N	None
19519	41	K/E	rs775586810	0.1341	gnomAD-4.0.0	42	None	0.9054	0.8861	29.3	N	-2.557	0.38	0.015381	-1.958	0.4367	0.0268	0.543662385431	3.235	0.999999	0.62	0.440604514059	0.999	0.598856925964	-3.07	0.457	0.712	0.004	None	None	1.59218E-06	0	0	0	0	None	0	0	1.59218E-06	2.85928E-06	0	0	None	N	None
19519	41	K/N	rs772071197	0.1341	gnomAD-2.1.1	42	None	0.9778	0.9756	24.4	D	-2.497	0.38	0.014011	-2.087	0.4675	0.2156	0.500188843923	3.785	0.999999	0.586	0.256283259241	1.0	0.616891205311	-3.83	0.441	0.824	0.003	None	None	4.03E-06	0	2.9E-05	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
19519	41	K/N	rs772071197	0.1341	gnomAD-4.0.0	42	None	0.9778	0.9756	24.4	D	-2.497	0.38	0.014011	-2.087	0.4675	0.2156	0.500188843923	3.785	0.999999	0.586	0.256283259241	1.0	0.616891205311	-3.83	0.441	0.824	0.003	None	None	1.59223E-06	0	2.28896E-05	0	0	None	0	0	1.59223E-06	0	0	0	None	N	None
19521	43	E/D	rs1156295835	0.2196	gnomAD-2.1.1	44	None	0.179	0.1259	18.4	N	-1.244	0.33	0.012282	-1.226	0.0741	-1.0355	0.0764562275565	None	0.999907	0.447	0.0611884634855	0.001	0.481802731752	-0.67	0.039	0.083	0.784	None	None	8.06E-06	0	0	9.97E-05	0	None	0	None	8.06E-06	0	8.91E-06	0	None	N	None
19521	43	E/D	rs1156295835	0.2196	gnomAD-4.0.0	44	None	0.179	0.1259	18.4	N	-1.244	0.33	0.012282	-1.226	0.0741	-1.0355	0.0764562275565	None	0.999907	0.447	0.0611884634855	0.001	0.481802731752	-0.67	0.039	0.083	0.784	None	None	3.18433E-06	0	0	4.77008E-05	0	None	0	0	3.18433E-06	2.8593E-06	0	0	None	N	None
19521	43	E/G	rs543122164	0.2196	gnomAD-2.1.1	44	None	0.5183	0.325	24.7	N	-1.112	0.28	0.044387	-1.064	0.2008	-0.6737	0.133499110863	2.37	0.999885	0.447	0.482209950775	0.549	0.465244948864	-4.43	0.32	0.456	0.059	None	None	4.03E-06	0	0	0	5.61E-05	None	0	None	4.03E-06	0	0	0	None	N	None
19521	43	E/G	rs543122164	0.2196	gnomAD-3.1.2	44	None	0.5183	0.325	24.7	N	-1.112	0.28	0.044387	-1.064	0.2008	-0.6737	0.133499110863	2.37	0.999885	0.447	0.482209950775	0.549	0.465244948864	-4.43	0.32	0.456	0.059	None	None	6.58E-06	0	0	0	1.94175E-04	None	0	0	6.58E-06	0	0	0	None	N	None
19521	43	E/G	rs543122164	0.2196	1000 genomes	44	None	0.5183	0.325	24.7	N	-1.112	0.28	0.044387	-1.064	0.2008	-0.6737	0.133499110863	2.37	0.999885	0.447	0.482209950775	0.549	0.465244948864	-4.43	0.32	0.456	0.059	None	None	1.99681E-04	0	0	None	1E-03	0	None	None	1.99681E-04	None	0	None	None	N	None
19521	43	E/G	rs543122164	0.2196	gnomAD-4.0.0	44	None	0.5183	0.325	24.7	N	-1.112	0.28	0.044387	-1.064	0.2008	-0.6737	0.133499110863	2.37	0.999885	0.447	0.482209950775	0.549	0.465244948864	-4.43	0.32	0.456	0.059	None	None	2.56333E-06	0	0	0	4.86997E-05	None	0	0	2.56333E-06	0	0	0	None	N	None
19521	43	E/K	rs746319976	0.2196	gnomAD-2.1.1	44	None	0.7126	0.5065	25.2	N	-0.338	0.39	0.033947	-0.763	0.151	-0.8582	0.128479209888	1.645	0.999981	0.604	0.394384168047	0.549	0.532165408134	-2.83	0.223	0.381	0.036	None	None	2.02E-05	0	1.45214E-04	0	0	None	0	None	2.02E-05	0	0	0	None	N	None
19521	43	E/K	rs746319976	0.2196	gnomAD-3.1.2	44	None	0.7126	0.5065	25.2	N	-0.338	0.39	0.033947	-0.763	0.151	-0.8582	0.128479209888	1.645	0.999981	0.604	0.394384168047	0.549	0.532165408134	-2.83	0.223	0.381	0.036	None	None	1.32E-05	0	1.31113E-04	0	0	None	0	0	1.32E-05	0	0	0	None	N	None
19521	43	E/K	rs746319976	0.2196	gnomAD-4.0.0	44	None	0.7126	0.5065	25.2	N	-0.338	0.39	0.033947	-0.763	0.151	-0.8582	0.128479209888	1.645	0.999981	0.604	0.394384168047	0.549	0.532165408134	-2.83	0.223	0.381	0.036	None	None	5.579E-06	0	1.5017E-04	0	0	None	0	0	5.579E-06	0	0	0	None	N	None
19521	43	E/V	rs543122164	0.2196	gnomAD-2.1.1	44	None	0.4538	0.2564	26.8	N	0.553	0.28	0.064932	0.095	0.2821	-0.4574	0.295493529801	2.025	0.999943	0.55	0.640367608718	0.896	0.466303855181	-4.9	0.388	0.457	0.008	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
19526	48	V/F	rs377682563	0.7466	gnomAD-2.1.1	64	None	0.1572	0.1115	13.07	N	-0.759	0.41	0.023273	-0.797	0.1355	-0.8376	0.141868470361	1.29	0.999996	0.455	0.273503213844	0.144	0.266975700855	-2.45	0.098	0.283	0.162	None	None	4.03E-06	0	0	0	5.61E-05	None	0	None	4.03E-06	0	0	0	None	I	None
19526	48	V/F	rs377682563	0.7466	gnomAD-4.0.0	64	None	0.1572	0.1115	13.07	N	-0.759	0.41	0.023273	-0.797	0.1355	-0.8376	0.141868470361	1.29	0.999996	0.455	0.273503213844	0.144	0.266975700855	-2.45	0.098	0.283	0.162	None	None	6.84375E-07	0	0	0	2.52666E-05	None	0	0	6.84375E-07	0	0	0	None	I	None
19526	48	V/I	rs377682563	0.7466	gnomAD-2.1.1	64	None	0.0711	0.0635	None	N	-0.189	None	None	-0.344	None	None	None	None	None	None	None	0.001	None	None	0.037	0.13	None	None	None	1.43085E-04	1.65344E-04	0	0	0	None	6.54E-05	None	1.43085E-04	0	2.58483E-04	1.40528E-04	None	I	None
19526	48	V/I	rs377682563	0.7466	gnomAD-3.1.2	64	None	0.0711	0.0635	None	N	-0.189	None	None	-0.344	None	None	None	None	None	None	None	0.001	None	None	0.037	0.13	None	None	None	1.90779E-04	7.25E-05	6.56E-05	0	0	None	0	0	1.90779E-04	3.53045E-04	0	4.78927E-04	None	I	None
19526	48	V/I	rs377682563	0.7466	1000 genomes	64	None	0.0711	0.0635	None	N	-0.189	None	None	-0.344	None	None	None	None	None	None	None	0.001	None	None	0.037	0.13	None	None	None	1.99681E-04	0	0	None	0	1E-03	None	None	1.99681E-04	None	0	None	None	I	None
19526	48	V/I	rs377682563	0.7466	gnomAD-4.0.0	64	None	0.0711	0.0635	None	N	-0.189	None	None	-0.344	None	None	None	None	None	None	None	0.001	None	None	0.037	0.13	None	None	None	3.30376E-04	8.00149E-05	3.33589E-05	0	0	None	0	1.65125E-04	3.30376E-04	4.22179E-04	7.68707E-05	3.04185E-04	None	I	None
19528	50	M/T	None	0.3924	gnomAD-4.0.0	66	None	0.2961	0.2599	23.8	N	None	0.53	0.027197	-1.072	0.0822	-0.9308	0.144161381094	-0.425	0.998886	0.432	0.710242159801	0.324	0.700312256813	-3.1	0.265	0.352	0.737	None	None	3.60097E-06	6.33473E-05	0	0	0	None	0	0	3.60097E-06	2.625E-06	0	0	None	N	None
19529	51	P/S	None	0.6684	gnomAD-4.0.0	67	None	0.2324	0.2388	27.8	N	None	0.52	0.011544	-0.585	0.2867	-0.5674	0.466644225527	1.68	0.999998	0.409	0.342865806769	1.0	0.604678809643	-4.83	0.351	0.813	0.246	None	None	4.10625E-06	0	0	0	0	None	0	0	4.10625E-06	5.39751E-06	0	0	None	N	None
19529	51	P/T	rs878972430	0.6684	gnomAD-2.1.1	67	None	0.1375	0.1333	27.2	N	-0.733	0.53	0.018806	-0.605	0.1821	-0.529	0.48919594472	0.47	0.999998	0.419	0.445711490874	1.0	0.633628189564	-4.43	0.367	0.804	0.546	None	None	3.19E-05	0	0	0	0	None	0	None	3.19E-05	0	6.49E-05	0	None	N	None
19529	51	P/T	rs878972430	0.6684	gnomAD-3.1.2	67	None	0.1375	0.1333	27.2	N	-0.733	0.53	0.018806	-0.605	0.1821	-0.529	0.48919594472	0.47	0.999998	0.419	0.445711490874	1.0	0.633628189564	-4.43	0.367	0.804	0.546	None	None	2.63E-05	0	0	0	0	None	0	0	2.63E-05	5.89E-05	0	0	None	N	None
19529	51	P/T	rs878972430	0.6684	gnomAD-4.0.0	67	None	0.1375	0.1333	27.2	N	-0.733	0.53	0.018806	-0.605	0.1821	-0.529	0.48919594472	0.47	0.999998	0.419	0.445711490874	1.0	0.633628189564	-4.43	0.367	0.804	0.546	None	None	3.71945E-06	0	0	0	0	None	0	0	3.71945E-06	5.08655E-06	0	0	None	N	None
19530	52	V/A	rs1187285216	0.2773	gnomAD-2.1.1	68	None	0.5517	0.5735	28.0	N	-1.618	0.39	0.012937	-1.2	0.3356	-0.371	0.504685203352	2.595	1.0	0.65	0.604839314244	0.999	0.587192893028	-3.07	0.389	0.563	0.055	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	I	None
19530	52	V/A	rs1187285216	0.2773	gnomAD-4.0.0	68	None	0.5517	0.5735	28.0	N	-1.618	0.39	0.012937	-1.2	0.3356	-0.371	0.504685203352	2.595	1.0	0.65	0.604839314244	0.999	0.587192893028	-3.07	0.389	0.563	0.055	None	None	3.18425E-06	0	0	0	2.78133E-05	None	0	0	3.18425E-06	0	1.43303E-05	0	None	I	None
19531	53	T/I	rs1258679826	0.2604	gnomAD-4.0.0	69	None	0.4899	0.4254	26.8	N	None	0.3	0.033196	-0.179	0.2935	-0.5767	0.292874867899	2.345	0.99999	0.561	0.357724736475	0.638	0.584712028503	-4.4	0.297	0.709	0.07	None	None	1.36873E-06	0	0	0	0	None	0	1.73611E-04	1.36873E-06	0	1.15955E-05	0	None	N	None
19531	53	T/R	rs1258679826	0.2604	gnomAD-2.1.1	69	None	0.6007	0.5372	27.1	N	-0.135	0.32	0.036325	-0.245	0.2988	-0.5673	0.311975432261	2.14	0.999996	0.642	0.503683571763	0.638	0.53903055191	-4.27	0.331	0.724	0.01	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	4.64E-05	0	0	None	N	None
19531	53	T/R	rs1258679826	0.2604	gnomAD-4.0.0	69	None	0.6007	0.5372	27.1	N	-0.135	0.32	0.036325	-0.245	0.2988	-0.5673	0.311975432261	2.14	0.999996	0.642	0.503683571763	0.638	0.53903055191	-4.27	0.331	0.724	0.01	None	None	6.84366E-07	0	0	0	0	None	1.87371E-05	0	6.84366E-07	0	0	0	None	N	None
19533	55	A/P	rs751194562	0.5640	gnomAD-2.1.1	75	None	0.702	0.7617	22.5	N	0.015	0.62	0.044749	-0.274	0.1442	-0.8707	0.261073601384	1.51	0.999996	0.484	0.245660935333	0.667	0.55936050415	-3.4	0.106	0.541	0.057	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	I	None
19533	55	A/P	rs751194562	0.5640	gnomAD-4.0.0	75	None	0.702	0.7617	22.5	N	0.015	0.62	0.044749	-0.274	0.1442	-0.8707	0.261073601384	1.51	0.999996	0.484	0.245660935333	0.667	0.55936050415	-3.4	0.106	0.541	0.057	None	None	3.18433E-06	0	0	0	0	None	0	0	3.18433E-06	5.71866E-06	0	0	None	I	None
19534	56	S/G	None	0.1671	gnomAD-4.0.0	77	None	0.1329	0.1325	22.4	N	None	0.51	0.016363	-1.109	0.1333	-0.928	0.0842442114282	0.82	0.94017	0.418	0.101711395817	0.012	0.350750207901	-2.7	0.057	0.347	0.156	None	None	1.59211E-06	0	0	0	0	None	0	0	1.59211E-06	0	1.43308E-05	0	None	N	None
19534	56	S/N	rs563833549	0.1671	gnomAD-2.1.1	77	None	0.2036	0.1732	21.7	N	-0.681	0.44	0.011291	-0.806	0.1226	-0.9465	0.0781518737448	1.37	0.937561	0.475	0.104622674875	None	0.398640871048	-2.0	0.119	0.14	0.279	None	None	3.22E-05	8.27E-05	1.13385E-04	1.93573E-04	0	None	0	None	3.22E-05	0	7.83E-06	0	None	N	None
19534	56	S/N	rs563833549	0.1671	gnomAD-3.1.2	77	None	0.2036	0.1732	21.7	N	-0.681	0.44	0.011291	-0.806	0.1226	-0.9465	0.0781518737448	1.37	0.937561	0.475	0.104622674875	None	0.398640871048	-2.0	0.119	0.14	0.279	None	None	3.29E-05	9.65E-05	6.56E-05	0	0	None	0	0	3.29E-05	0	0	0	None	N	None
19534	56	S/N	rs563833549	0.1671	1000 genomes	77	None	0.2036	0.1732	21.7	N	-0.681	0.44	0.011291	-0.806	0.1226	-0.9465	0.0781518737448	1.37	0.937561	0.475	0.104622674875	None	0.398640871048	-2.0	0.119	0.14	0.279	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
19534	56	S/N	rs563833549	0.1671	gnomAD-4.0.0	77	None	0.2036	0.1732	21.7	N	-0.681	0.44	0.011291	-0.806	0.1226	-0.9465	0.0781518737448	1.37	0.937561	0.475	0.104622674875	None	0.398640871048	-2.0	0.119	0.14	0.279	None	None	1.67353E-05	9.33134E-05	1.00087E-04	0	0	None	0	0	1.67353E-05	8.47736E-06	0	6.40389E-05	None	N	None
19536	58	K/E	None	0.7674	gnomAD-4.0.0	88	None	0.2531	0.2254	25.4	N	None	0.57	0.032671	0.097	0.2222	-0.6788	0.382947142725	0.525	0.999993	0.547	0.33340067248	0.961	0.634584844112	-2.87	0.266	0.459	0.094	None	None	3.18421E-06	0	0	0	0	None	0	0	3.18421E-06	0	2.86607E-05	0	None	N	None
19537	59	T/R	None	0.2245	gnomAD-4.0.0	89	None	0.3016	0.2786	25.0	N	None	0.31	0.031916	-0.189	0.3549	-0.3505	0.334990745553	2.55	0.999986	0.667	0.568036332872	0.667	0.6084420681	-4.6	0.472	0.628	0.043	None	None	6.84382E-07	0	0	0	0	None	0	0	6.84382E-07	8.99583E-07	0	0	None	N	None
19537	59	T/S	rs750320421	0.2245	gnomAD-2.1.1	89	None	0.2314	0.204	23.4	N	-0.949	0.34	0.029458	-0.859	0.199	-0.7224	0.120956172942	2.515	0.996248	0.59	0.141422826196	0.22	0.544582247734	-3.07	0.193	0.435	0.049	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
19537	59	T/S	rs750320421	0.2245	gnomAD-3.1.2	89	None	0.2314	0.204	23.4	N	-0.949	0.34	0.029458	-0.859	0.199	-0.7224	0.120956172942	2.515	0.996248	0.59	0.141422826196	0.22	0.544582247734	-3.07	0.193	0.435	0.049	None	None	1.97E-05	4.83E-05	0	0	0	None	0	0	1.97E-05	1.47E-05	0	0	None	N	None
19537	59	T/S	rs750320421	0.2245	gnomAD-4.0.0	89	None	0.2314	0.204	23.4	N	-0.949	0.34	0.029458	-0.859	0.199	-0.7224	0.120956172942	2.515	0.996248	0.59	0.141422826196	0.22	0.544582247734	-3.07	0.193	0.435	0.049	None	None	5.12726E-06	3.38467E-05	0	0	0	None	0	0	5.12726E-06	4.78792E-06	0	0	None	N	None
19538	60	T/A	rs200017524	0.3787	gnomAD-2.1.1	90	None	0.0996	0.0999	None	N	-0.811	None	None	-0.876	None	None	None	None	None	None	None	0.9	None	None	0.249	0.46	None	None	None	4.54308E-04	4.46465E-03	3.4029E-04	0	0	None	0	None	4.54308E-04	0	4.7E-05	1.40687E-04	None	N	None
19538	60	T/A	rs200017524	0.3787	gnomAD-3.1.2	90	None	0.0996	0.0999	None	N	-0.811	None	None	-0.876	None	None	None	None	None	None	None	0.9	None	None	0.249	0.46	None	None	None	1.40725E-03	4.63499E-03	6.55136E-04	0	0	None	0	0	1.40725E-03	5.88E-05	0	3.83142E-03	None	N	None
19538	60	T/A	rs200017524	0.3787	1000 genomes	90	None	0.0996	0.0999	None	N	-0.811	None	None	-0.876	None	None	None	None	None	None	None	0.9	None	None	0.249	0.46	None	None	None	1.19808E-03	4.5E-03	0	None	0	0	None	None	1.19808E-03	None	0	None	None	N	None
19538	60	T/A	rs200017524	0.3787	gnomAD-4.0.0	90	None	0.0996	0.0999	None	N	-0.811	None	None	-0.876	None	None	None	None	None	None	None	0.9	None	None	0.249	0.46	None	None	None	2.61564E-04	4.69296E-03	4.16945E-04	6.7595E-05	0	None	0	1.6518E-04	2.61564E-04	1.52593E-05	0	3.84234E-04	None	N	None
19538	60	T/I	rs370686112	0.3787	gnomAD-3.1.2	90	None	0.1994	0.2088	28.0	N	None	0.27	0.031009	-0.195	0.4056	-0.2683	0.466674898207	2.785	0.998149	0.502	0.565649094883	0.997	0.575815856457	-4.1	0.433	0.722	0.144	None	None	6.58E-06	0	0	0	0	None	9.43E-05	0	6.58E-06	0	0	0	None	N	None
19538	60	T/I	rs370686112	0.3787	gnomAD-4.0.0	90	None	0.1994	0.2088	28.0	N	None	0.27	0.031009	-0.195	0.4056	-0.2683	0.466674898207	2.785	0.998149	0.502	0.565649094883	0.997	0.575815856457	-4.1	0.433	0.722	0.144	None	None	6.57877E-06	0	0	0	0	None	9.42507E-05	0	6.57877E-06	0	0	0	None	N	None
19538	60	T/K	rs370686112	0.3787	gnomAD-2.1.1	90	None	0.263	0.2416	None	N	-0.374	None	None	-0.593	None	None	None	None	None	None	None	0.994	None	None	0.368	0.691	None	None	None	3.22E-05	3.72055E-04	0	0	0	None	0	None	3.22E-05	0	0	0	None	N	None
19538	60	T/K	rs370686112	0.3787	gnomAD-3.1.2	90	None	0.263	0.2416	None	N	-0.374	None	None	-0.593	None	None	None	None	None	None	None	0.994	None	None	0.368	0.691	None	None	None	1.0526E-04	3.86436E-04	0	0	0	None	0	0	1.0526E-04	0	0	0	None	N	None
19538	60	T/K	rs370686112	0.3787	gnomAD-4.0.0	90	None	0.263	0.2416	None	N	-0.374	None	None	-0.593	None	None	None	None	None	None	None	0.994	None	None	0.368	0.691	None	None	None	2.54157E-05	5.47689E-04	0	0	0	None	0	0	2.54157E-05	0	0	0	None	N	None
19539	61	C/F	rs539868284	0.1504	gnomAD-2.1.1	91	None	0.2373	0.2697	32.0	N	-1.027	0.53	0.017959	-0.679	0.2303	-0.598	0.57123600094	0.98	1.0	0.55	0.746742446189	1.0	0.625880360603	-7.4	0.424	0.853	0.221	None	None	1.21E-05	0	0	0	0	None	0	None	1.21E-05	0	2.67E-05	0	None	N	None
19539	61	C/F	rs539868284	0.1504	gnomAD-3.1.2	91	None	0.2373	0.2697	32.0	N	-1.027	0.53	0.017959	-0.679	0.2303	-0.598	0.57123600094	0.98	1.0	0.55	0.746742446189	1.0	0.625880360603	-7.4	0.424	0.853	0.221	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
19539	61	C/F	rs539868284	0.1504	gnomAD-4.0.0	91	None	0.2373	0.2697	32.0	N	-1.027	0.53	0.017959	-0.679	0.2303	-0.598	0.57123600094	0.98	1.0	0.55	0.746742446189	1.0	0.625880360603	-7.4	0.424	0.853	0.221	None	None	6.81905E-06	0	0	0	0	None	0	0	6.81905E-06	9.32535E-06	0	0	None	N	None
19539	61	C/R	rs753678261	0.1504	gnomAD-2.1.1	91	None	0.8281	0.8342	26.6	N	-0.431	0.41	0.022073	-0.21	0.3871	-0.1826	0.615612516959	3.265	1.0	0.648	0.825775482533	1.0	0.698008716106	-8.43	0.545	0.875	0.015	None	None	2.82E-05	0	0	0	3.92773E-04	None	0	None	2.82E-05	0	0	0	None	N	None
19539	61	C/R	rs753678261	0.1504	gnomAD-3.1.2	91	None	0.8281	0.8342	26.6	N	-0.431	0.41	0.022073	-0.21	0.3871	-0.1826	0.615612516959	3.265	1.0	0.648	0.825775482533	1.0	0.698008716106	-8.43	0.545	0.875	0.015	None	None	1.97E-05	0	0	0	5.82072E-04	None	0	0	1.97E-05	0	0	0	None	N	None
19539	61	C/R	rs753678261	0.1504	gnomAD-4.0.0	91	None	0.8281	0.8342	26.6	N	-0.431	0.41	0.022073	-0.21	0.3871	-0.1826	0.615612516959	3.265	1.0	0.648	0.825775482533	1.0	0.698008716106	-8.43	0.545	0.875	0.015	None	None	1.05377E-05	0	0	0	3.5775E-04	None	0	0	1.05377E-05	0	0	1.60149E-05	None	N	None
19539	61	C/S	rs753678261	0.1504	gnomAD-2.1.1	91	None	0.549	0.586	29.8	N	-1.141	0.42	0.010027	-0.88	0.3999	-0.253	0.511892525395	2.46	1.0	0.599	0.694136321851	1.0	0.609964609146	-7.0	0.546	0.689	0.015	None	None	4.03E-06	0	0	0	0	None	0	None	4.03E-06	0	8.91E-06	0	None	N	None
19539	61	C/S	rs753678261	0.1504	gnomAD-4.0.0	91	None	0.549	0.586	29.8	N	-1.141	0.42	0.010027	-0.88	0.3999	-0.253	0.511892525395	2.46	1.0	0.599	0.694136321851	1.0	0.609964609146	-7.0	0.546	0.689	0.015	None	None	1.36875E-06	0	0	0	0	None	0	0	1.36875E-06	1.79915E-06	0	0	None	N	None
19540	62	K/I	rs2050741869	0.3578	gnomAD-4.0.0	92	None	0.624	0.6042	28.7	N	None	0.42	0.027911	0.437	0.3291	-0.396	0.615612516959	1.93	1.0	0.57	0.574056412462	1.0	0.572862744331	-5.93	0.339	0.812	0.008	None	None	1.59229E-06	0	0	0	2.7835E-05	None	0	0	1.59229E-06	0	0	0	None	N	None
19541	63	V/A	rs760841948	0.1251	gnomAD-2.1.1	93	None	0.6485	0.4498	24.5	N	-2.293	0.08	0.034773	-1.959	0.2059	-0.7802	0.108086438741	2.23	0.999363	0.687	0.427596317008	0.025	0.578534722328	-3.07	0.211	0.373	0.003	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
19541	63	V/A	rs760841948	0.1251	gnomAD-4.0.0	93	None	0.6485	0.4498	24.5	N	-2.293	0.08	0.034773	-1.959	0.2059	-0.7802	0.108086438741	2.23	0.999363	0.687	0.427596317008	0.025	0.578534722328	-3.07	0.211	0.373	0.003	None	None	1.59233E-06	0	0	0	0	None	0	0	1.59233E-06	0	1.43308E-05	0	None	N	None
19542	64	S/P	rs145198325	0.3906	gnomAD-2.1.1	94	None	0.0514	0.0485	None	N	-0.208	None	None	0.053	None	None	None	None	None	None	None	None	None	None	0.108	0.215	None	None	None	2.42E-05	1.93773E-04	8.72E-05	0	0	None	0	None	2.42E-05	0	0	0	None	N	None
19542	64	S/P	rs145198325	0.3906	gnomAD-3.1.2	94	None	0.0514	0.0485	None	N	-0.208	None	None	0.053	None	None	None	None	None	None	None	None	None	None	0.108	0.215	None	None	None	1.05213E-04	3.61934E-04	0	0	0	None	0	0	1.05213E-04	0	0	0	None	N	None
19542	64	S/P	rs145198325	0.3906	1000 genomes	94	None	0.0514	0.0485	None	N	-0.208	None	None	0.053	None	None	None	None	None	None	None	None	None	None	0.108	0.215	None	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	N	None
19542	64	S/P	rs145198325	0.3906	gnomAD-4.0.0	94	None	0.0514	0.0485	None	N	-0.208	None	None	0.053	None	None	None	None	None	None	None	None	None	None	0.108	0.215	None	None	None	1.98349E-05	3.59904E-04	6.67223E-05	0	0	None	0	0	1.98349E-05	0	0	0	None	N	None
19542	64	S/Y	None	0.3906	gnomAD-4.0.0	94	None	0.2097	0.1797	26.4	D	None	0.29	0.100208	-0.372	0.286	-0.5364	0.173436500226	1.71	0.923635	0.453	0.666034180468	0.295	0.407944977283	-2.47	0.312	0.519	0.01	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
19543	65	K/E	None	0.8582	gnomAD-4.0.0	96	None	0.5704	0.5168	26.0	N	None	0.43	0.011874	-0.311	0.3018	-0.4776	0.543662385431	2.13	0.999999	0.515	0.357313475932	0.999	0.635779619217	-3.07	0.337	0.613	0.014	None	None	1.59232E-06	0	0	0	0	None	0	0	1.59232E-06	0	1.43308E-05	0	None	N	None
19544	66	L/P	rs373353480	0.1132	gnomAD-3.1.2	97	None	0.9923	0.987	None	D	-1.698	None	None	-1.595	None	None	None	None	None	None	None	1.0	None	None	0.912	0.827	None	None	None	1.31E-05	0	0	0	0	None	0	0	1.31E-05	2.94E-05	0	0	None	N	None
19544	66	L/P	rs373353480	0.1132	gnomAD-4.0.0	97	None	0.9923	0.987	None	D	-1.698	None	None	-1.595	None	None	None	None	None	None	None	1.0	None	None	0.912	0.827	None	None	None	8.97355E-06	0	0	0	0	None	0	0	8.97355E-06	1.67585E-05	0	0	None	N	None
19544	66	L/V	rs772132591	0.1132	gnomAD-2.1.1	97	None	0.5069	0.4195	25.0	D	-1.672	-1.9	0.039432	-1.595	0.7549	0.6179	0.465770963553	2.395	0.998869	0.763	0.764855773497	0.999	0.592388510704	-2.3	0.699	0.835	0.012	None	None	4.03E-06	0	0	0	0	None	3.27E-05	None	4.03E-06	0	0	0	None	N	None
19544	66	L/V	rs772132591	0.1132	gnomAD-4.0.0	97	None	0.5069	0.4195	25.0	D	-1.672	-1.9	0.039432	-1.595	0.7549	0.6179	0.465770963553	2.395	0.998869	0.763	0.764855773497	0.999	0.592388510704	-2.3	0.699	0.835	0.012	None	None	4.1066E-06	0	0	0	0	None	0	0	4.1066E-06	0	6.95717E-05	0	None	N	None
19546	68	E/Q	rs201840554	0.4781	gnomAD-2.1.1	99	None	0.2461	0.2577	None	N	-0.224	None	None	-0.366	None	None	None	None	None	None	None	1.0	None	None	0.354	0.673	None	None	None	9.91836E-04	1.0508E-02	3.12181E-04	0	0	None	0	None	9.91836E-04	0	4.7E-05	8.44832E-04	None	N	None
19546	68	E/Q	rs201840554	0.4781	gnomAD-3.1.2	99	None	0.2461	0.2577	None	N	-0.224	None	None	-0.366	None	None	None	None	None	None	None	1.0	None	None	0.354	0.673	None	None	None	2.93355E-03	1.04313E-02	3.93494E-04	0	0	None	0	0	2.93355E-03	8.83E-05	0	9.5511E-04	None	N	None
19546	68	E/Q	rs201840554	0.4781	1000 genomes	99	None	0.2461	0.2577	None	N	-0.224	None	None	-0.366	None	None	None	None	None	None	None	1.0	None	None	0.354	0.673	None	None	None	2.19649E-03	8.3E-03	0	None	0	0	None	None	2.19649E-03	None	0	None	None	N	None
19546	68	E/Q	rs201840554	0.4781	gnomAD-4.0.0	99	None	0.2461	0.2577	None	N	-0.224	None	None	-0.366	None	None	None	None	None	None	None	1.0	None	None	0.354	0.673	None	None	None	5.47979E-04	1.08272E-02	3.83794E-04	0	0	None	0	3.30469E-04	5.47979E-04	9.32537E-06	3.29468E-05	5.28372E-04	None	N	None
19547	69	G/E	rs374713701	0.2984	gnomAD-2.1.1	100	None	0.4679	0.4496	None	N	-1.185	None	None	-1.466	None	None	None	None	None	None	None	1.0	None	None	0.634	0.858	None	None	None	8.07E-06	6.46E-05	0	0	0	None	0	None	8.07E-06	0	8.92E-06	0	None	N	None
19547	69	G/E	rs374713701	0.2984	gnomAD-4.0.0	100	None	0.4679	0.4496	None	N	-1.185	None	None	-1.466	None	None	None	None	None	None	None	1.0	None	None	0.634	0.858	None	None	None	1.57427E-05	0	0	0	0	None	0	0	1.57427E-05	2.06912E-05	0	0	None	N	None
19547	69	G/R	rs886055260	0.2984	gnomAD-4.0.0	100	None	0.7635	0.7753	27.7	N	None	0.01	0.024641	-0.785	0.5348	0.1179	0.506463245118	3.425	1.0	0.747	0.498259528926	1.0	0.743345499039	-6.13	0.625	0.851	0.059	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
19547	69	G/V	rs374713701	0.2984	gnomAD-2.1.1	100	None	0.8451	0.8355	None	D	-0.388	None	None	-0.53	None	None	None	None	None	None	None	1.0	None	None	0.588	0.841	None	None	None	4.03E-06	6.46E-05	0	0	0	None	0	None	4.03E-06	0	0	0	None	N	None
19547	69	G/V	rs374713701	0.2984	gnomAD-3.1.2	100	None	0.8451	0.8355	None	D	-0.388	None	None	-0.53	None	None	None	None	None	None	None	1.0	None	None	0.588	0.841	None	None	None	2.63E-05	9.65E-05	0	0	0	None	0	0	2.63E-05	0	0	0	None	N	None
19547	69	G/V	rs374713701	0.2984	gnomAD-4.0.0	100	None	0.8451	0.8355	None	D	-0.388	None	None	-0.53	None	None	None	None	None	None	None	1.0	None	None	0.588	0.841	None	None	None	2.6303E-05	9.65391E-05	0	0	0	None	0	0	2.6303E-05	0	0	0	None	N	None
19549	71	D/Y	rs1472080899	0.2773	gnomAD-2.1.1	103	None	0.2169	0.1997	25.5	N	0.095	0.35	0.015241	0.025	0.268	-0.6047	0.492780550998	2.095	0.999997	0.519	0.341696514166	0.997	0.536029875278	-5.53	0.433	0.785	0.004	None	None	8.07E-06	0	0	0	0	None	6.54E-05	None	8.07E-06	0	0	0	None	N	None
19549	71	D/Y	rs1472080899	0.2773	gnomAD-3.1.2	103	None	0.2169	0.1997	25.5	N	0.095	0.35	0.015241	0.025	0.268	-0.6047	0.492780550998	2.095	0.999997	0.519	0.341696514166	0.997	0.536029875278	-5.53	0.433	0.785	0.004	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	0	2.07125E-04	0	None	N	None
19549	71	D/Y	rs1472080899	0.2773	gnomAD-4.0.0	103	None	0.2169	0.1997	25.5	N	0.095	0.35	0.015241	0.025	0.268	-0.6047	0.492780550998	2.095	0.999997	0.519	0.341696514166	0.997	0.536029875278	-5.53	0.433	0.785	0.004	None	None	4.33978E-06	0	0	3.37952E-05	0	None	0	0	4.33978E-06	1.69559E-06	3.2946E-05	1.60195E-05	None	N	None
19550	72	Y/C	rs770314252	0.1103	gnomAD-2.1.1	104	None	0.8434	0.7753	32.0	D	-1.652	-2.5	0.076334	-2.098	0.8752	0.985	0.517459491388	4.03	1.0	0.913	0.895564509889	1.0	0.712573289871	-6.9	0.857	0.877	0.002	None	None	7.17E-06	0	0	0	0	None	0	None	7.17E-06	0	1.57E-05	0	None	N	None
19550	72	Y/C	rs770314252	0.1103	gnomAD-3.1.2	104	None	0.8434	0.7753	32.0	D	-1.652	-2.5	0.076334	-2.098	0.8752	0.985	0.517459491388	4.03	1.0	0.913	0.895564509889	1.0	0.712573289871	-6.9	0.857	0.877	0.002	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
19550	72	Y/C	rs770314252	0.1103	gnomAD-4.0.0	104	None	0.8434	0.7753	32.0	D	-1.652	-2.5	0.076334	-2.098	0.8752	0.985	0.517459491388	4.03	1.0	0.913	0.895564509889	1.0	0.712573289871	-6.9	0.857	0.877	0.002	None	None	1.17788E-05	0	0	0	2.23894E-05	None	0	0	1.17788E-05	1.44118E-05	0	1.60195E-05	None	N	None
19550	72	Y/D	None	0.1103	gnomAD-4.0.0	104	None	0.9863	0.9815	27.2	D	None	-2.5	0.134313	-3.8	0.9004	1.0617	0.615612516959	4.38	1.0	0.928	0.837468629341	1.0	0.702553272247	-7.67	0.896	0.877	0.006	None	None	1.59279E-06	0	0	0	0	None	0	0	1.59279E-06	0	1.43336E-05	0	None	N	None
19550	72	Y/H	rs2154186587	0.1103	gnomAD-3.1.2	104	None	0.9406	0.9165	26.9	D	None	-2.5	0.113664	-2.348	0.9004	1.0617	0.52537510995	4.03	0.999999	0.915	0.802906345537	1.0	0.711462080479	-3.83	0.862	0.818	0.002	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
19550	72	Y/H	rs2154186587	0.1103	gnomAD-4.0.0	104	None	0.9406	0.9165	26.9	D	None	-2.5	0.113664	-2.348	0.9004	1.0617	0.52537510995	4.03	0.999999	0.915	0.802906345537	1.0	0.711462080479	-3.83	0.862	0.818	0.002	None	None	2.56394E-06	0	0	0	0	None	0	0	2.56394E-06	4.78854E-06	0	0	None	N	None
19551	73	I/V	rs1264084790	0.1920	gnomAD-4.0.0	105	None	0.0782	0.0695	24.1	N	None	0.51	0.009015	-1.058	0.0699	-1.0163	0.0719583658917	0.045	0.706418	0.409	0.302793454619	0.001	0.371669203043	-0.53	0.06	0.237	0.267	None	None	3.18563E-06	0	0	0	5.57569E-05	None	0	0	3.18563E-06	0	0	0	None	N	None
19553	75	R/G	None	0.1566	gnomAD-2.1.1	107	None	0.9321	0.9147	None	D	-2.172	None	None	-2.044	None	None	None	None	None	None	None	0.922	None	None	0.47	0.591	None	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.94E-06	0	None	N	None
19553	75	R/G	None	0.1566	gnomAD-3.1.2	107	None	0.9321	0.9147	None	D	-2.172	None	None	-2.044	None	None	None	None	None	None	None	0.922	None	None	0.47	0.591	None	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
19553	75	R/G	None	0.1566	gnomAD-4.0.0	107	None	0.9321	0.9147	None	D	-2.172	None	None	-2.044	None	None	None	None	None	None	None	0.922	None	None	0.47	0.591	None	None	None	3.10014E-06	1.33618E-05	0	0	0	None	0	0	3.10014E-06	3.39115E-06	0	0	None	N	None
19553	75	R/P	None	0.1566	gnomAD-4.0.0	107	None	0.9983	0.9982	24.9	D	None	0.14	0.104102	-0.923	0.5511	0.4754	0.521877933732	4.33	0.999988	0.777	0.614679400128	0.988	0.443678706884	-5.37	0.522	0.68	0.005	None	None	3.42273E-06	0	0	0	0	None	0	0	3.42273E-06	4.49817E-06	0	0	None	N	None
19553	75	R/Q	rs543279513	0.1566	gnomAD-2.1.1	107	None	0.3011	0.2679	None	N	-1.068	None	None	-1.157	None	None	None	None	None	None	None	0.447	None	None	0.314	0.475	None	None	None	1.08E-05	1.24152E-04	0	0	0	None	0	None	1.08E-05	0	0	0	None	N	None
19553	75	R/Q	rs543279513	0.1566	gnomAD-3.1.2	107	None	0.3011	0.2679	None	N	-1.068	None	None	-1.157	None	None	None	None	None	None	None	0.447	None	None	0.314	0.475	None	None	None	1.97E-05	7.24E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	N	None
19553	75	R/Q	rs543279513	0.1566	1000 genomes	107	None	0.3011	0.2679	None	N	-1.068	None	None	-1.157	None	None	None	None	None	None	None	0.447	None	None	0.314	0.475	None	None	None	3.99361E-04	1.5E-03	0	None	0	0	None	None	3.99361E-04	None	0	None	None	N	None
19553	75	R/Q	rs543279513	0.1566	gnomAD-4.0.0	107	None	0.3011	0.2679	None	N	-1.068	None	None	-1.157	None	None	None	None	None	None	None	0.447	None	None	0.314	0.475	None	None	None	7.43962E-06	5.33305E-05	0	0	0	None	0	0	7.43962E-06	5.93453E-06	1.09847E-05	0	None	N	None
19553	75	R/W	rs372959465	0.1566	gnomAD-2.1.1	107	None	0.737	0.6937	None	D	-0.666	None	None	-0.26	None	None	None	None	None	None	None	1.0	None	None	0.526	0.729	None	None	None	1.43E-05	8.28E-05	0	0	5.2E-05	None	0	None	1.43E-05	0	7.85E-06	0	None	N	None
19553	75	R/W	rs372959465	0.1566	gnomAD-3.1.2	107	None	0.737	0.6937	None	D	-0.666	None	None	-0.26	None	None	None	None	None	None	None	1.0	None	None	0.526	0.729	None	None	None	1.97E-05	4.83E-05	0	0	0	None	0	0	1.97E-05	1.47E-05	0	0	None	N	None
19553	75	R/W	rs372959465	0.1566	gnomAD-4.0.0	107	None	0.737	0.6937	None	D	-0.666	None	None	-0.26	None	None	None	None	None	None	None	1.0	None	None	0.526	0.729	None	None	None	1.30206E-05	4.00855E-05	0	0	2.24024E-05	None	0	0	1.30206E-05	1.35646E-05	1.09837E-05	0	None	N	None
19554	76	I/L	rs879139698	0.0577	gnomAD-4.0.0	108	None	0.4717	0.4492	25.7	N	None	0.31	0.011427	-1.805	0.3317	-0.3985	0.456683706047	2.665	0.999998	0.73	0.631849437455	0.993	0.70325756073	-1.53	0.379	0.343	0.012	None	None	2.40064E-06	1.26695E-04	0	0	0	None	0	0	2.40064E-06	0	0	0	None	N	None
19554	76	I/T	rs974431132	0.0577	gnomAD-2.1.1	108	None	0.977	0.9739	28.7	N	-3.572	0.13	0.016346	-3.75	0.3918	-0.2215	0.51877166463	3.09	1.0	0.701	0.798160069708	1.0	0.77240049839	-3.77	0.524	0.785	0.002	None	None	4.04E-06	0	0	0	0	None	3.27E-05	None	4.04E-06	0	0	0	None	N	None
19554	76	I/T	rs974431132	0.0577	gnomAD-4.0.0	108	None	0.977	0.9739	28.7	N	-3.572	0.13	0.016346	-3.75	0.3918	-0.2215	0.51877166463	3.09	1.0	0.701	0.798160069708	1.0	0.77240049839	-3.77	0.524	0.785	0.002	None	None	3.18593E-06	0	0	0	0	None	0	0	3.18593E-06	0	2.86664E-05	0	None	N	None
19555	77	H/R	None	0.1784	gnomAD-4.0.0	109	None	0.1776	0.1608	20.9	N	None	0.54	0.004847	-1.878	0.0398	-0.9938	0.102427798663	-2.89	0.999949	0.539	0.0716867268079	None	0.440449774265	-4.07	0.195	0.236	0.355	None	None	1.59301E-06	0	0	0	0	None	0	0	1.59301E-06	0	1.43345E-05	0	None	N	None
19555	77	H/Y	rs1289211242	0.1784	gnomAD-2.1.1	109	None	0.0812	0.0714	17.48	N	0.178	0.47	0.004268	0.384	0.0397	-0.9862	0.0969859525798	-2.35	0.999967	0.56	0.0716867268079	None	0.437106251717	-2.16	0.144	0.158	1.0	None	None	4.04E-06	0	0	0	0	None	0	None	4.04E-06	0	8.94E-06	0	None	N	None
19555	77	H/Y	rs1289211242	0.1784	gnomAD-4.0.0	109	None	0.0812	0.0714	17.48	N	0.178	0.47	0.004268	0.384	0.0397	-0.9862	0.0969859525798	-2.35	0.999967	0.56	0.0716867268079	None	0.437106251717	-2.16	0.144	0.158	1.0	None	None	6.84543E-06	0	0	0	0	None	0	0	6.84543E-06	8.9963E-06	0	0	None	N	None
19557	79	E/K	None	0.2705	gnomAD-4.0.0	111	None	0.5557	0.4938	24.7	N	None	0.44	0.037412	-0.473	0.2451	-0.6394	0.305504204818	2.095	0.999997	0.589	0.34854441366	0.956	0.735117077827	-2.87	0.282	0.513	0.121	None	None	2.40065E-06	0	0	0	0	None	0	0	2.40065E-06	1.31251E-06	6.07533E-05	0	None	I	None
19558	80	N/K	rs1455635388	0.0979	gnomAD-3.1.2	112	None	0.9992	0.9991	24.8	D	None	0.15	0.02178	-0.353	0.4828	-0.0521	0.496214373149	4.31	0.999721	0.773	0.28492961333	1.0	0.773243069649	-4.6	0.563	0.763	None	None	None	6.57E-06	0	0	0	0	None	0	0	6.57E-06	1.47E-05	0	0	None	N	None
19558	80	N/K	rs1455635388	0.0979	gnomAD-4.0.0	112	None	0.9992	0.9991	24.8	D	None	0.15	0.02178	-0.353	0.4828	-0.0521	0.496214373149	4.31	0.999721	0.773	0.28492961333	1.0	0.773243069649	-4.6	0.563	0.763	None	None	None	6.57445E-06	0	0	0	0	None	0	0	6.57445E-06	1.47054E-05	0	0	None	N	None
19558	80	N/S	rs369224233	0.0979	gnomAD-2.1.1	112	None	0.9251	0.9457	None	N	-1.396	None	None	-1.252	None	None	None	None	None	None	None	0.999	None	None	0.589	0.601	None	None	None	7.18E-06	8.27E-05	0	0	0	None	0	None	7.18E-06	0	0	0	None	N	None
19558	80	N/S	rs369224233	0.0979	gnomAD-3.1.2	112	None	0.9251	0.9457	None	N	-1.396	None	None	-1.252	None	None	None	None	None	None	None	0.999	None	None	0.589	0.601	None	None	None	1.31E-05	4.82E-05	0	0	0	None	0	0	1.31E-05	0	0	0	None	N	None
19558	80	N/S	rs369224233	0.0979	gnomAD-4.0.0	112	None	0.9251	0.9457	None	N	-1.396	None	None	-1.252	None	None	None	None	None	None	None	0.999	None	None	0.589	0.601	None	None	None	3.84724E-06	5.07408E-05	0	0	0	None	0	0	3.84724E-06	0	0	0	None	N	None
19559	81	L/M	None	0.7447	gnomAD-4.0.0	113	None	0.1145	0.1098	24.2	N	None	0.43	0.006516	-0.554	0.09	-0.9965	0.0990663541488	0.105	0.937649	0.427	0.413761986042	0.136	0.577549695969	-0.93	0.035	0.253	0.355	None	None	6.84595E-07	2.98954E-05	0	0	0	None	0	0	6.84595E-07	0	0	0	None	I	None
19559	81	L/Q	rs76604657	0.7447	gnomAD-2.1.1	113	None	0.1522	0.1423	None	N	-0.209	None	None	-0.373	None	None	None	None	None	None	None	0.966	None	None	0.382	0.49	None	None	None	1.43533E-04	0	0	0	2.07987E-03	None	0	None	1.43533E-04	0	0	0	None	I	None
19559	81	L/Q	rs76604657	0.7447	gnomAD-3.1.2	113	None	0.1522	0.1423	None	N	-0.209	None	None	-0.373	None	None	None	None	None	None	None	0.966	None	None	0.382	0.49	None	None	None	1.18315E-04	0	0	0	3.48567E-03	None	0	0	1.18315E-04	0	0	0	None	I	None
19559	81	L/Q	rs76604657	0.7447	1000 genomes	113	None	0.1522	0.1423	None	N	-0.209	None	None	-0.373	None	None	None	None	None	None	None	0.966	None	None	0.382	0.49	None	None	None	5.99042E-04	0	0	None	3E-03	0	None	None	5.99042E-04	None	0	None	None	I	None
19559	81	L/Q	rs76604657	0.7447	gnomAD-4.0.0	113	None	0.1522	0.1423	None	N	-0.209	None	None	-0.373	None	None	None	None	None	None	None	0.966	None	None	0.382	0.49	None	None	None	1.76068E-04	0	0	0	6.34358E-03	None	0	0	1.76068E-04	0	0	1.60169E-05	None	I	None
19559	81	L/V	None	0.7447	gnomAD-4.0.0	113	None	0.087	0.0854	24.0	N	None	0.49	0.010648	-0.388	0.0881	-0.9994	0.129289507032	0.415	0.92483	0.463	0.459463830659	0.454	0.545124471188	-1.7	0.087	0.359	0.472	None	None	6.84595E-07	0	0	3.82848E-05	0	None	0	0	6.84595E-07	0	0	0	None	I	None
19561	83	G/A	rs372491628	0.1993	gnomAD-2.1.1	115	None	0.9304	0.9205	26.4	D	-0.473	-0.34	0.030109	-0.72	0.6881	0.6376	0.480971576196	3.995	1.0	0.661	0.59827724986	1.0	0.807599008083	-4.6	0.588	0.764	0.004	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.95E-06	0	None	I	None
19561	83	G/A	rs372491628	0.1993	gnomAD-3.1.2	115	None	0.9304	0.9205	26.4	D	-0.473	-0.34	0.030109	-0.72	0.6881	0.6376	0.480971576196	3.995	1.0	0.661	0.59827724986	1.0	0.807599008083	-4.6	0.588	0.764	0.004	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
19561	83	G/A	rs372491628	0.1993	gnomAD-4.0.0	115	None	0.9304	0.9205	26.4	D	-0.473	-0.34	0.030109	-0.72	0.6881	0.6376	0.480971576196	3.995	1.0	0.661	0.59827724986	1.0	0.807599008083	-4.6	0.588	0.764	0.004	None	None	4.34038E-06	0	0	0	0	None	0	0	4.34038E-06	5.93476E-06	0	0	None	I	None
19561	83	G/E	rs372491628	0.1993	gnomAD-2.1.1	115	None	0.9919	0.9903	None	D	-0.689	None	None	-1.188	None	None	None	None	None	None	None	1.0	None	None	0.668	0.907	None	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.95E-06	0	None	I	None
19561	83	G/R	rs760399687	0.1993	gnomAD-2.1.1	115	None	0.9849	0.982	28.0	D	-0.522	-0.35	0.033385	-0.697	0.6603	0.5294	0.506463245118	4.345	1.0	0.693	0.647335815468	1.0	0.85526496172	-6.13	0.65	0.917	0.002	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.95E-06	0	None	I	None
19561	83	G/R	rs760399687	0.1993	gnomAD-3.1.2	115	None	0.9849	0.982	28.0	D	-0.522	-0.35	0.033385	-0.697	0.6603	0.5294	0.506463245118	4.345	1.0	0.693	0.647335815468	1.0	0.85526496172	-6.13	0.65	0.917	0.002	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	I	None
19561	83	G/R	rs760399687	0.1993	gnomAD-4.0.0	115	None	0.9849	0.982	28.0	D	-0.522	-0.35	0.033385	-0.697	0.6603	0.5294	0.506463245118	4.345	1.0	0.693	0.647335815468	1.0	0.85526496172	-6.13	0.65	0.917	0.002	None	None	5.1307E-06	0	0	0	0	None	0	0	5.1307E-06	9.57864E-06	0	0	None	I	None
19562	84	I/L	rs397517637	0.4633	gnomAD-2.1.1	117	None	0.1718	0.1747	24.3	N	-1.113	0.67	0.013948	-0.991	0.0946	-1.0371	0.0916761220119	0.905	0.999942	0.371	0.44318313171	0.031	0.734163284302	-1.47	0.121	0.267	0.14	None	None	7.18E-06	8.28E-05	0	0	0	None	0	None	7.18E-06	0	0	0	None	I	None
19562	84	I/L	rs397517637	0.4633	gnomAD-3.1.2	117	None	0.1718	0.1747	24.3	N	-1.113	0.67	0.013948	-0.991	0.0946	-1.0371	0.0916761220119	0.905	0.999942	0.371	0.44318313171	0.031	0.734163284302	-1.47	0.121	0.267	0.14	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	I	None
19562	84	I/L	rs397517637	0.4633	gnomAD-4.0.0	117	None	0.1718	0.1747	24.3	N	-1.113	0.67	0.013948	-0.991	0.0946	-1.0371	0.0916761220119	0.905	0.999942	0.371	0.44318313171	0.031	0.734163284302	-1.47	0.121	0.267	0.14	None	None	6.57272E-06	2.41161E-05	0	0	0	None	0	0	6.57272E-06	0	0	0	None	I	None
19562	84	I/R	None	0.4633	gnomAD-4.0.0	117	None	0.3825	0.3901	28.0	N	None	0.6	0.034508	-0.316	0.2115	-0.7118	0.427318418718	1.655	1.0	0.502	0.67247961064	0.879	0.765022397041	-5.17	0.374	0.82	0.001	None	None	4.80129E-06	0	0	0	0	None	0	0	4.80129E-06	5.25001E-06	0	0	None	I	None
19562	84	I/V	rs397517637	0.4633	gnomAD-4.0.0	117	None	0.1012	0.0986	23.8	N	None	0.66	0.008294	-1.189	0.0799	-1.07	0.0719583658917	0.44	0.99986	0.377	0.384919354899	0.001	0.662133276463	-0.67	0.115	0.223	0.29	None	None	6.00164E-06	0	0	0	0	None	0	0	6.00164E-06	5.25002E-06	0	3.66327E-05	None	I	None
19563	85	S/N	rs759628569	0.0857	gnomAD-2.1.1	118	None	0.9697	0.9706	None	D	-1.549	None	None	-1.369	None	None	None	None	None	None	None	0.999	None	None	0.499	0.679	None	None	None	8.09E-06	0	0	0	0	None	3.27E-05	None	8.09E-06	0	8.95E-06	0	None	N	None
19563	85	S/N	rs759628569	0.0857	gnomAD-3.1.2	118	None	0.9697	0.9706	None	D	-1.549	None	None	-1.369	None	None	None	None	None	None	None	0.999	None	None	0.499	0.679	None	None	None	1.97E-05	0	6.55E-05	0	0	None	0	0	1.97E-05	2.94E-05	0	0	None	N	None
19563	85	S/N	rs759628569	0.0857	gnomAD-4.0.0	118	None	0.9697	0.9706	None	D	-1.549	None	None	-1.369	None	None	None	None	None	None	None	0.999	None	None	0.499	0.679	None	None	None	1.79818E-05	0	1.66962E-05	0	0	None	0	0	1.79818E-05	2.20433E-05	1.09876E-05	1.60241E-05	None	N	None
19564	86	D/E	rs1236959839	0.6103	gnomAD-2.1.1	119	None	0.1703	0.153	24.2	N	-0.475	0.71	0.014929	-0.494	0.0687	-1.0724	0.103124469384	0.43	0.998858	0.356	0.101711395817	0.17	0.726748347282	-2.73	0.092	0.268	0.328	None	None	3.19E-05	0	0	0	6.52742E-04	None	0	None	3.19E-05	0	0	0	None	I	None
19564	86	D/E	rs1236959839	0.6103	gnomAD-3.1.2	119	None	0.1703	0.153	24.2	N	-0.475	0.71	0.014929	-0.494	0.0687	-1.0724	0.103124469384	0.43	0.998858	0.356	0.101711395817	0.17	0.726748347282	-2.73	0.092	0.268	0.328	None	None	6.57E-06	0	0	0	1.93874E-04	None	0	0	6.57E-06	0	0	0	None	I	None
19564	86	D/E	rs1236959839	0.6103	gnomAD-4.0.0	119	None	0.1703	0.153	24.2	N	-0.475	0.71	0.014929	-0.494	0.0687	-1.0724	0.103124469384	0.43	0.998858	0.356	0.101711395817	0.17	0.726748347282	-2.73	0.092	0.268	0.328	None	None	6.08982E-06	0	0	0	2.27583E-04	None	0	0	6.08982E-06	4.81979E-06	0	0	None	I	None
19564	86	D/N	rs182400450	0.6103	gnomAD-2.1.1	119	None	0.1482	0.1325	None	N	-0.81	None	None	-0.398	None	None	None	None	None	None	None	0.046	None	None	0.174	0.231	None	None	None	4.05E-06	6.47E-05	0	0	0	None	0	None	4.05E-06	0	0	0	None	I	None
19564	86	D/N	rs182400450	0.6103	gnomAD-3.1.2	119	None	0.1482	0.1325	None	N	-0.81	None	None	-0.398	None	None	None	None	None	None	None	0.046	None	None	0.174	0.231	None	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	I	None
19564	86	D/N	rs182400450	0.6103	1000 genomes	119	None	0.1482	0.1325	None	N	-0.81	None	None	-0.398	None	None	None	None	None	None	None	0.046	None	None	0.174	0.231	None	None	None	1.99681E-04	8E-04	0	None	0	0	None	None	1.99681E-04	None	0	None	None	I	None
19564	86	D/N	rs182400450	0.6103	gnomAD-4.0.0	119	None	0.1482	0.1325	None	N	-0.81	None	None	-0.398	None	None	None	None	None	None	None	0.046	None	None	0.174	0.231	None	None	None	6.56961E-06	2.40512E-05	0	0	0	None	0	0	6.56961E-06	0	0	0	None	I	None
19564	86	D/Y	None	0.6103	gnomAD-4.0.0	119	None	0.3291	0.2978	26.6	N	None	0.59	0.020091	-0.13	0.3712	-0.2478	0.492780550998	3.465	0.999999	0.456	0.36256342048	0.999	0.749537110329	-6.27	0.305	0.772	0.003	None	None	3.18728E-06	0	0	0	0	None	0	2.41896E-04	3.18728E-06	2.86053E-06	0	0	None	I	None
19565	87	P/H	None	0.3359	gnomAD-4.0.0	120	None	0.5205	0.4597	32.0	N	None	0.42	0.020496	-1.681	0.4934	0.132	0.49825478594	3.815	1.0	0.386	0.546174653742	1.0	0.738579392433	-6.9	0.445	0.793	0.006	None	None	2.40065E-06	0	0	0	0	None	0	0	2.40065E-06	2.625E-06	0	0	None	I	None
19565	87	P/L	rs878880222	0.3359	gnomAD-2.1.1	120	None	0.5072	0.4726	None	N	-0.724	None	None	-0.925	None	None	None	None	None	None	None	1.0	None	None	0.485	0.812	None	None	None	3.19E-05	1.14784E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	I	None
19565	87	P/L	rs878880222	0.3359	gnomAD-3.1.2	120	None	0.5072	0.4726	None	N	-0.724	None	None	-0.925	None	None	None	None	None	None	None	1.0	None	None	0.485	0.812	None	None	None	1.97E-05	7.24E-05	0	0	0	None	0	0	1.97E-05	0	0	0	None	I	None
19565	87	P/L	rs878880222	0.3359	gnomAD-4.0.0	120	None	0.5072	0.4726	None	N	-0.724	None	None	-0.925	None	None	None	None	None	None	None	1.0	None	None	0.485	0.812	None	None	None	1.97306E-05	7.24323E-05	0	0	0	None	0	0	1.97306E-05	0	0	0	None	I	None
19567	89	V/A	rs763514219	0.3777	gnomAD-2.1.1	122	None	0.2181	0.1952	23.5	N	-1.274	0.3	0.013464	-0.882	0.1215	-0.9246	0.115832161471	-0.025	0.986989	0.398	0.389283895039	0.435	0.469884604216	-2.27	0.186	0.429	0.756	None	None	4.05E-06	0	0	0	0	None	0	None	4.05E-06	0	8.96E-06	0	None	N	None
19567	89	V/A	rs763514219	0.3777	gnomAD-4.0.0	122	None	0.2181	0.1952	23.5	N	-1.274	0.3	0.013464	-0.882	0.1215	-0.9246	0.115832161471	-0.025	0.986989	0.398	0.389283895039	0.435	0.469884604216	-2.27	0.186	0.429	0.756	None	None	1.02704E-05	0	0	0	0	None	0	3.47464E-04	1.02704E-05	1.16962E-05	0	0	None	N	None
19567	89	V/L	None	0.3777	gnomAD-4.0.0	122	None	0.1339	0.1082	22.6	N	None	0.31	0.007247	-0.271	0.1179	-1.0147	0.0821069030307	-0.08	0.990245	0.321	0.290962096972	0.002	0.44876652956	-1.53	0.188	0.191	0.373	None	None	1.20032E-06	0	0	0	0	None	0	0	1.20032E-06	1.3125E-06	0	0	None	N	None
19567	89	V/M	rs1448926202	0.3777	gnomAD-2.1.1	122	None	0.1593	0.1254	24.1	N	-0.453	0.22	0.019859	-0.416	0.1853	-0.7594	0.169774760906	0.685	0.988132	0.305	0.415313616471	0.868	0.473608672619	-1.58	0.152	0.483	0.112	None	None	3.19E-05	1.14837E-04	0	0	0	None	0	None	3.19E-05	0	0	0	None	N	None
19567	89	V/M	rs1448926202	0.3777	gnomAD-3.1.2	122	None	0.1593	0.1254	24.1	N	-0.453	0.22	0.019859	-0.416	0.1853	-0.7594	0.169774760906	0.685	0.988132	0.305	0.415313616471	0.868	0.473608672619	-1.58	0.152	0.483	0.112	None	None	1.32E-05	4.83E-05	0	0	0	None	0	0	1.32E-05	0	0	0	None	N	None
19567	89	V/M	rs1448926202	0.3777	gnomAD-4.0.0	122	None	0.1593	0.1254	24.1	N	-0.453	0.22	0.019859	-0.416	0.1853	-0.7594	0.169774760906	0.685	0.988132	0.305	0.415313616471	0.868	0.473608672619	-1.58	0.152	0.483	0.112	None	None	1.31544E-05	4.82928E-05	0	0	0	None	0	0	1.31544E-05	0	0	0	None	N	None
19568	90	S/C	rs1465396608	0.1440	gnomAD-2.1.1	123	None	0.5052	0.4398	32.0	N	-0.323	0.03	0.015766	-0.101	0.5709	0.181	0.456698694381	3.15	1.0	0.426	0.535439087667	1.0	0.663216233253	-3.73	0.486	0.797	0.001	None	None	4.05E-06	0	0	0	0	None	3.28E-05	None	4.05E-06	0	0	0	None	N	None
19568	90	S/C	rs1465396608	0.1440	gnomAD-4.0.0	123	None	0.5052	0.4398	32.0	N	-0.323	0.03	0.015766	-0.101	0.5709	0.181	0.456698694381	3.15	1.0	0.426	0.535439087667	1.0	0.663216233253	-3.73	0.486	0.797	0.001	None	None	1.59417E-06	0	0	0	0	None	0	0	1.59417E-06	0	1.43678E-05	0	None	N	None
19569	91	D/N	rs397517638	0.9253	gnomAD-2.1.1	125	None	0.0962	0.0956	23.7	N	0.353	0.16	0.036677	-0.016	0.2004	-0.6553	0.143002494057	1.71	0.999565	0.333	0.330069100803	0.915	0.517246127129	-3.0	0.203	0.499	0.031	None	None	8.11E-06	0	0	0	0	None	3.29E-05	None	8.11E-06	0	8.96E-06	0	None	N	None
19569	91	D/N	rs397517638	0.9253	gnomAD-3.1.2	125	None	0.0962	0.0956	23.7	N	0.353	0.16	0.036677	-0.016	0.2004	-0.6553	0.143002494057	1.71	0.999565	0.333	0.330069100803	0.915	0.517246127129	-3.0	0.203	0.499	0.031	None	None	6.58E-06	0	0	0	0	None	0	0	6.58E-06	1.47E-05	0	0	None	N	None
19569	91	D/N	rs397517638	0.9253	gnomAD-4.0.0	125	None	0.0962	0.0956	23.7	N	0.353	0.16	0.036677	-0.016	0.2004	-0.6553	0.143002494057	1.71	0.999565	0.333	0.330069100803	0.915	0.517246127129	-3.0	0.203	0.499	0.031	None	None	1.86072E-06	0	0	0	0	None	0	0	1.86072E-06	1.69579E-06	1.10135E-05	0	None	N	None
19571	93	M/V	rs770228515	0.1882	gnomAD-2.1.1	127	None	0.0625	0.0641	23.6	N	-1.461	0.55	0.022395	-1.315	0.0888	-1.0325	0.0848295226273	-0.555	0.983778	0.321	0.357519025918	None	0.437649071217	-2.3	0.276	0.149	0.382	None	None	8.11E-06	0	0	0	0	None	0	None	8.11E-06	0	1.79E-05	0	None	N	None
19571	93	M/V	rs770228515	0.1882	gnomAD-4.0.0	127	None	0.0625	0.0641	23.6	N	-1.461	0.55	0.022395	-1.315	0.0888	-1.0325	0.0848295226273	-0.555	0.983778	0.321	0.357519025918	None	0.437649071217	-2.3	0.276	0.149	0.382	None	None	8.90388E-06	0	0	0	0	None	0	0	8.90388E-06	1.07974E-05	0	1.65893E-05	None	N	None
19574	96	K/E	rs1032128606	0.6722	gnomAD-3.1.2	131	None	0.2018	0.2001	25.2	N	None	0.2	0.033726	0.07	0.2878	-0.5727	0.126302431423	2.42	0.99998	0.428	0.27132560031	0.104	0.468582093716	-2.82	0.246	0.431	0.009	None	None	6.57E-06	2.41E-05	0	0	0	None	0	0	6.57E-06	0	0	0	None	N	None
19574	96	K/E	rs1032128606	0.6722	gnomAD-4.0.0	131	None	0.2018	0.2001	25.2	N	None	0.2	0.033726	0.07	0.2878	-0.5727	0.126302431423	2.42	0.99998	0.428	0.27132560031	0.104	0.468582093716	-2.82	0.246	0.431	0.009	None	None	6.57376E-06	2.41266E-05	0	0	0	None	0	0	6.57376E-06	0	0	0	None	N	None
19575	97	D/Y	rs748522705	0.4854	gnomAD-2.1.1	132	None	0.5565	0.5162	28.6	N	0.109	0.11	0.017217	0.155	0.3185	-0.4676	0.367357544423	2.405	1.0	0.421	0.426670027402	0.995	0.659301996231	-6.9	0.464	0.771	0.06	None	None	4.07E-06	0	2.93E-05	0	0	None	0	None	4.07E-06	0	0	0	None	N	None
19575	97	D/Y	rs748522705	0.4854	gnomAD-4.0.0	132	None	0.5565	0.5162	28.6	N	0.109	0.11	0.017217	0.155	0.3185	-0.4676	0.367357544423	2.405	1.0	0.421	0.426670027402	0.995	0.659301996231	-6.9	0.464	0.771	0.06	None	None	1.5961E-06	0	2.30213E-05	0	0	None	0	0	1.5961E-06	0	0	0	None	N	None

Whole Population MAF	African (AFR)	Latin American (AMR)
Amish (AMS)	Ashkenazi Jewish (ASJ)	East Asian (EAS)
European/1KGP (EUR)	Finnish (FIN)	Middle Eastern (MDE)
Non-Finnish European (NFE)	South Asian (SAS)	Other (OTH)

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