Structural position:
- Domain Type: Fn3
- Aligned Position: 89
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C/F | 15714 |
Fn3-1 |
58 | rs750388617 |
0.4373 | -1.22 | 0.996 | N | 0.553 | 0.39 | 0.631375494303 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| C/F | 15714 |
Fn3-1 |
58 | rs750388617 |
0.4373 | -1.22 | 0.996 | N | 0.553 | 0.39 | 0.631375494303 | gnomAD-4.0.0 | 6.84605E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65837E-05 |
| C/S | 15714 |
Fn3-1 |
58 | None | 0.285 | None | 0.704 | N | 0.415 | 0.193 | 0.520161069619 | gnomAD-4.0.0 | 6.84605E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99881E-07 | 0 | 0 |
| L/Q | 15917 |
Fn3-3 |
59 | None | 0.1876 | None | 1.0 | N | 0.801 | 0.479 | 0.704706922069 | gnomAD-4.0.0 | 3.38924E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.21543E-05 | 0 |
| L/V | 16112 |
Fn3-4 |
58 | rs747917712 |
0.1083 | -1.045 | 0.722 | N | 0.465 | 0.185 | 0.396794106654 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| L/V | 16112 |
Fn3-4 |
58 | rs747917712 |
0.1083 | -1.045 | 0.722 | N | 0.465 | 0.185 | 0.396794106654 | gnomAD-4.0.0 | 3.42527E-06 | None | None | None | None | N | None | 2.99796E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70086E-06 | 0 | 1.6597E-05 |
| T/I | 16212 |
Fn3-5 |
58 | None | 0.291 | None | 0.565 | D | 0.525 | 0.294 | 0.402043589563 | gnomAD-4.0.0 | 1.59506E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03324E-05 |
| T/K | 16508 |
Fn3-7 |
59 | rs1429836100 |
0.3774 | None | 0.993 | N | 0.663 | 0.406 | 0.469333501611 | gnomAD-4.0.0 | 7.97443E-06 | None | None | None | None | N | None | 0 | 2.28812E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.21278E-04 |
| T/R | 16508 |
Fn3-7 |
59 | None | 0.3258 | None | 0.997 | N | 0.717 | 0.402 | 0.520427616228 | gnomAD-4.0.0 | 1.59489E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86521E-06 | 0 | 0 |
| T/A | 16708 |
Fn3-9 |
58 | rs2056500591 |
0.1644 | None | 0.625 | D | 0.471 | 0.278 | 0.220303561663 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 16708 |
Fn3-9 |
58 | rs2056500591 |
0.1644 | None | 0.625 | D | 0.471 | 0.278 | 0.220303561663 | gnomAD-4.0.0 | 2.56635E-06 | None | None | None | None | N | None | 0 | 1.69745E-05 | None | 0 | 0 | None | 0 | 2.24719E-04 | 0 | 0 | 0 |
| T/N | 16708 |
Fn3-9 |
58 | rs777539591 |
0.2841 | -0.752 | 0.989 | N | 0.465 | 0.284 | 0.372268306217 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/N | 16708 |
Fn3-9 |
58 | rs777539591 |
0.2841 | -0.752 | 0.989 | N | 0.465 | 0.284 | 0.372268306217 | gnomAD-4.0.0 | 1.36939E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31922E-05 | 0 |
| T/P | 16708 |
Fn3-9 |
58 | None | 0.2606 | None | 0.989 | N | 0.527 | 0.488 | 0.430579932962 | gnomAD-4.0.0 | 1.59389E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03214E-05 |
| T/S | 16708 |
Fn3-9 |
58 | None | 0.2685 | None | 0.891 | N | 0.475 | 0.286 | 0.199424873507 | gnomAD-4.0.0 | 1.36939E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79969E-06 | 0 | 0 |
| C/R | 16809 |
Fn3-10 |
59 | None | 0.7163 | None | 1.0 | N | 0.817 | 0.497 | 0.498830998431 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/S | 16910 |
Fn3-11 |
59 | rs1161195119 |
0.5107 | -2.683 | 0.998 | N | 0.712 | 0.429 | 0.72290962679 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| L/S | 16910 |
Fn3-11 |
59 | rs1161195119 |
0.5107 | -2.683 | 0.998 | N | 0.712 | 0.429 | 0.72290962679 | gnomAD-4.0.0 | 1.59288E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86146E-06 | 0 | 0 |
| L/V | 16910 |
Fn3-11 |
59 | rs1559779803 |
0.1526 | None | 0.996 | N | 0.581 | 0.167 | 0.405150804464 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 0 | 0 | 0 |
| L/V | 16910 |
Fn3-11 |
59 | rs1559779803 |
0.1526 | None | 0.996 | N | 0.581 | 0.167 | 0.405150804464 | gnomAD-4.0.0 | 6.57505E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 3.40136E-03 | 0 | 0 | 0 |
| L/P | 17104 |
Fn3-12 |
58 | rs1301202997 |
0.2999 | -0.929 | 1.0 | N | 0.7 | 0.492 | 0.699866572147 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| L/P | 17104 |
Fn3-12 |
58 | rs1301202997 |
0.2999 | -0.929 | 1.0 | N | 0.7 | 0.492 | 0.699866572147 | gnomAD-4.0.0 | 1.59279E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4332E-05 | 0 |
| L/R | 17104 |
Fn3-12 |
58 | rs1301202997 |
0.3138 | None | 1.0 | N | 0.711 | 0.469 | 0.659250127719 | gnomAD-4.0.0 | 3.18558E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.5534E-05 | None | 0 | 0 | 0 | 0 | 0 |
| C/G | 17428 |
Fn3-14 |
60 | rs2055534842 |
0.238 | None | 1.0 | N | 0.791 | 0.378 | 0.78109972193 | gnomAD-4.0.0 | 3.18769E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.58098E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 17627 |
Fn3-16 |
59 | rs767433978 |
0.1458 | -0.816 | 1.0 | N | 0.707 | 0.319 | 0.504235531984 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 8.88E-06 | 0 |
| R/C | 17627 |
Fn3-16 |
59 | rs767433978 |
0.1458 | -0.816 | 1.0 | N | 0.707 | 0.319 | 0.504235531984 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 17627 |
Fn3-16 |
59 | rs767433978 |
0.1458 | -0.816 | 1.0 | N | 0.707 | 0.319 | 0.504235531984 | gnomAD-4.0.0 | 4.34014E-06 | None | None | None | None | N | None | 4.00898E-05 | 0 | None | 0 | 2.23594E-05 | None | 0 | 0 | 2.5438E-06 | 0 | 0 |
| R/G | 17627 |
Fn3-16 |
59 | None | 0.3719 | None | 0.988 | N | 0.587 | 0.34 | 0.512883945787 | gnomAD-4.0.0 | 6.84474E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99755E-07 | 0 | 0 |
| R/H | 17627 |
Fn3-16 |
59 | rs536494011 |
0.1397 | -1.296 | 1.0 | N | 0.628 | 0.299 | 0.17948927462 | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 0 | None | 0 | None | 4E-05 | 1.0157E-04 | 0 |
| R/H | 17627 |
Fn3-16 |
59 | rs536494011 |
0.1397 | -1.296 | 1.0 | N | 0.628 | 0.299 | 0.17948927462 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.42E-05 | 0 | 0 |
| R/H | 17627 |
Fn3-16 |
59 | rs536494011 |
0.1397 | -1.296 | 1.0 | N | 0.628 | 0.299 | 0.17948927462 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/H | 17627 |
Fn3-16 |
59 | rs536494011 |
0.1397 | -1.296 | 1.0 | N | 0.628 | 0.299 | 0.17948927462 | gnomAD-4.0.0 | 3.3478E-05 | None | None | None | None | N | None | 2.66773E-05 | 3.33567E-05 | None | 0 | 0 | None | 1.5627E-05 | 0 | 3.56141E-05 | 2.19616E-05 | 8.0082E-05 |
| T/I | 17920 |
Fn3-18 |
59 | None | 0.2505 | None | 0.852 | N | 0.444 | 0.402 | 0.483816155017 | gnomAD-4.0.0 | 1.59419E-06 | None | None | None | None | N | None | 0 | 2.28791E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 17920 |
Fn3-18 |
59 | rs2054577412 |
0.1009 | None | 0.996 | N | 0.595 | 0.439 | 0.473300991676 | gnomAD-4.0.0 | 1.68045E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.8375E-05 | 0 | 0 |
| V/L | 18229 |
Fn3-20 |
64 | rs116142642 |
0.2312 | -0.269 | None | N | 0.083 | 0.107 | 0.193865811164 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | I | None | 0 | 1.4486E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 18229 |
Fn3-20 |
64 | rs116142642 |
0.2312 | -0.269 | None | N | 0.083 | 0.107 | 0.193865811164 | gnomAD-4.0.0 | 3.4227E-06 | None | None | None | None | I | None | 0 | 1.11842E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 18229 |
Fn3-20 |
64 | rs116142642 |
0.1855 | -0.349 | 0.808 | N | 0.28 | 0.055 | None | gnomAD-2.1.1 | 1.39335E-04 | None | None | None | None | I | None | 1.65508E-04 | 0 | None | 0 | 8.73946E-04 | None | 3.59501E-04 | None | 0 | 3.13E-05 | 4.21467E-04 |
| V/M | 18229 |
Fn3-20 |
64 | rs116142642 |
0.1855 | -0.349 | 0.808 | N | 0.28 | 0.055 | None | gnomAD-3.1.2 | 1.11891E-04 | None | None | None | None | I | None | 2.41464E-04 | 0 | 0 | 0 | 5.83885E-04 | None | 0 | 0 | 5.89E-05 | 0 | 0 |
| V/M | 18229 |
Fn3-20 |
64 | rs116142642 |
0.1855 | -0.349 | 0.808 | N | 0.28 | 0.055 | None | 1000 genomes | 5.99042E-04 | None | None | None | None | I | None | 8E-04 | 0 | None | None | 2E-03 | 0 | None | None | None | 0 | None |
| V/M | 18229 |
Fn3-20 |
64 | rs116142642 |
0.1855 | -0.349 | 0.808 | N | 0.28 | 0.055 | None | gnomAD-4.0.0 | 6.94407E-05 | None | None | None | None | I | None | 2.80187E-04 | 0 | None | 0 | 5.80435E-04 | None | 0 | 0 | 2.20491E-05 | 3.07591E-04 | 1.76186E-04 |
| L/Q | 18642 |
Fn3-23 |
64 | rs140714512 |
0.1979 | -1.503 | 0.879 | N | 0.644 | 0.247 | None | gnomAD-2.1.1 | 4.83133E-04 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 5.3367E-03 | 0 | None | 6.54E-05 | None | 0 | 5.41822E-04 | 9.83699E-04 |
| L/Q | 18642 |
Fn3-23 |
64 | rs140714512 |
0.1979 | -1.503 | 0.879 | N | 0.644 | 0.247 | None | gnomAD-3.1.2 | 4.67228E-04 | None | None | None | None | N | None | 2.41E-05 | 5.24728E-04 | 0 | 6.62442E-03 | 0 | None | 0 | 3.16456E-03 | 5.59268E-04 | 0 | 0 |
| L/Q | 18642 |
Fn3-23 |
64 | rs140714512 |
0.1979 | -1.503 | 0.879 | N | 0.644 | 0.247 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| L/Q | 18642 |
Fn3-23 |
64 | rs140714512 |
0.1979 | -1.503 | 0.879 | N | 0.644 | 0.247 | None | gnomAD-4.0.0 | 3.50269E-04 | None | None | None | None | N | None | 1.33394E-05 | 1.66761E-04 | None | 5.57885E-03 | 0 | None | 1.56235E-05 | 9.91736E-04 | 2.80667E-04 | 3.29518E-05 | 7.6859E-04 |
| C/G | 18842 |
Fn3-24 |
59 | None | 0.1854 | None | 1.0 | N | 0.783 | 0.498 | 0.760305313083 | gnomAD-4.0.0 | 6.9777E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.07079E-07 | 0 | 0 |
| C/R | 18842 |
Fn3-24 |
59 | rs371437953 |
0.2533 | -0.69 | 1.0 | N | 0.836 | 0.516 | None | gnomAD-2.1.1 | 8.95E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.91E-05 | 0 |
| C/R | 18842 |
Fn3-24 |
59 | rs371437953 |
0.2533 | -0.69 | 1.0 | N | 0.836 | 0.516 | None | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/R | 18842 |
Fn3-24 |
59 | rs371437953 |
0.2533 | -0.69 | 1.0 | N | 0.836 | 0.516 | None | gnomAD-4.0.0 | 1.893E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.56334E-06 | 0 | 0 |
| C/Y | 18842 |
Fn3-24 |
59 | None | 0.3065 | None | 1.0 | N | 0.816 | 0.443 | 0.659526208185 | gnomAD-4.0.0 | 6.97818E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0708E-07 | 0 | 0 |
| V/A | 18946 |
Fn3-25 |
63 | None | 0.4125 | None | 0.994 | N | 0.397 | 0.243 | 0.480574121323 | gnomAD-4.0.0 | 1.59226E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85994E-06 | 0 | 0 |
| T/A | 19046 |
Fn3-26 |
59 | rs1177930416 |
0.1385 | -0.711 | 0.349 | N | 0.417 | 0.249 | 0.210429274316 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| T/A | 19046 |
Fn3-26 |
59 | rs1177930416 |
0.1385 | -0.711 | 0.349 | N | 0.417 | 0.249 | 0.210429274316 | gnomAD-4.0.0 | 1.3691E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73792E-04 | 8.99706E-07 | 0 | 0 |
| T/I | 19046 |
Fn3-26 |
59 | rs1039868345 |
0.3855 | None | 0.82 | N | 0.605 | 0.505 | 0.56542871222 | gnomAD-4.0.0 | 1.59307E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86056E-06 | 0 | 0 |
| T/R | 19046 |
Fn3-26 |
59 | rs1039868345 |
0.2038 | None | 0.949 | N | 0.635 | 0.409 | 0.677692543746 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/I | 19342 |
Fn3-28 |
59 | None | 0.7893 | None | 0.998 | N | 0.71 | 0.34 | 0.596289430357 | gnomAD-4.0.0 | 2.05311E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69887E-06 | 0 | 0 |
| R/K | 19342 |
Fn3-28 |
59 | None | 0.1788 | None | 0.973 | N | 0.555 | 0.26 | 0.201204373187 | gnomAD-4.0.0 | 6.84371E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99622E-07 | 0 | 0 |
| T/R | 19537 |
Fn3-29 |
59 | None | 0.3016 | None | 0.667 | N | 0.628 | 0.472 | 0.568036332872 | gnomAD-4.0.0 | 6.84382E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99583E-07 | 0 | 0 |
| T/S | 19537 |
Fn3-29 |
59 | rs750320421 |
0.2314 | -0.949 | 0.22 | N | 0.435 | 0.193 | 0.141422826196 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/S | 19537 |
Fn3-29 |
59 | rs750320421 |
0.2314 | -0.949 | 0.22 | N | 0.435 | 0.193 | 0.141422826196 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/S | 19537 |
Fn3-29 |
59 | rs750320421 |
0.2314 | -0.949 | 0.22 | N | 0.435 | 0.193 | 0.141422826196 | gnomAD-4.0.0 | 5.12726E-06 | None | None | None | None | N | None | 3.38467E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78792E-06 | 0 | 0 |
| T/A | 19637 |
Fn3-30 |
59 | rs780393880 |
0.1101 | -0.675 | 0.64 | N | 0.476 | 0.246 | 0.176091768786 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/S | 19637 |
Fn3-30 |
59 | rs780393880 |
0.1306 | -0.978 | 0.103 | N | 0.499 | 0.234 | 0.154104182512 | gnomAD-2.1.1 | 2.81E-05 | None | None | None | None | N | None | 0 | 2.03016E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/S | 19637 |
Fn3-30 |
59 | rs780393880 |
0.1306 | -0.978 | 0.103 | N | 0.499 | 0.234 | 0.154104182512 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
| K/N | 19934 |
Fn3-32 |
58 | rs1363638353 |
0.4559 | -0.792 | 0.642 | N | 0.425 | 0.139 | 0.183819452728 | gnomAD-2.1.1 | 8.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| K/N | 19934 |
Fn3-32 |
58 | rs1363638353 |
0.4559 | -0.792 | 0.642 | N | 0.425 | 0.139 | 0.183819452728 | gnomAD-4.0.0 | 3.18587E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72014E-06 | 0 | 0 |
| L/V | 20033 |
Fn3-33 |
57 | rs878993043 |
0.1257 | -0.923 | 0.946 | N | 0.428 | 0.123 | None | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| L/V | 20033 |
Fn3-33 |
57 | rs878993043 |
0.1257 | -0.923 | 0.946 | N | 0.428 | 0.123 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 0 | 0 |
| L/V | 20033 |
Fn3-33 |
57 | rs878993043 |
0.1257 | -0.923 | 0.946 | N | 0.428 | 0.123 | None | gnomAD-4.0.0 | 1.02556E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.67605E-05 | 0 | 2.84495E-05 |
| T/A | 20229 |
Fn3-34 |
59 | rs747588848 |
0.1097 | None | 0.055 | N | 0.439 | 0.187 | 0.20549828249 | gnomAD-4.0.0 | 2.73735E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52169E-05 | None | 0 | 0 | 2.69885E-06 | 0 | 0 |
| T/I | 20229 |
Fn3-34 |
59 | None | 0.2408 | None | 0.124 | N | 0.512 | 0.166 | 0.259761712551 | gnomAD-4.0.0 | 1.59205E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85987E-06 | 0 | 0 |
| C/G | 20430 |
Fn3-36 |
60 | None | 0.5093 | None | 1.0 | N | 0.757 | 0.568 | 0.782359736722 | gnomAD-4.0.0 | 6.84667E-07 | None | None | None | None | I | None | 0 | 0 | None | 3.8323E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 20430 |
Fn3-36 |
60 | rs527704660 |
0.8308 | -1.153 | 1.0 | N | 0.797 | 0.432 | 0.604686531655 | gnomAD-2.1.1 | 7.54E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.68299E-04 | None | 0 | None | 0 | 7.07E-05 | 1.41084E-04 |
| C/Y | 20430 |
Fn3-36 |
60 | rs527704660 |
0.8308 | -1.153 | 1.0 | N | 0.797 | 0.432 | 0.604686531655 | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 9.70497E-04 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| C/Y | 20430 |
Fn3-36 |
60 | rs527704660 |
0.8308 | -1.153 | 1.0 | N | 0.797 | 0.432 | 0.604686531655 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| C/Y | 20430 |
Fn3-36 |
60 | rs527704660 |
0.8308 | -1.153 | 1.0 | N | 0.797 | 0.432 | 0.604686531655 | gnomAD-4.0.0 | 5.33305E-05 | None | None | None | None | I | None | 2.66759E-05 | 0 | None | 0 | 6.25978E-04 | None | 0 | 0 | 4.66404E-05 | 0 | 1.60195E-05 |
| R/Q | 20626 |
Fn3-37 |
58 | rs745731267 |
0.1863 | -0.37 | 1.0 | N | 0.739 | 0.363 | 0.202086224978 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| R/Q | 20626 |
Fn3-37 |
58 | rs745731267 |
0.1863 | -0.37 | 1.0 | N | 0.739 | 0.363 | 0.202086224978 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/Q | 20626 |
Fn3-37 |
58 | rs745731267 |
0.1863 | -0.37 | 1.0 | N | 0.739 | 0.363 | 0.202086224978 | gnomAD-4.0.0 | 1.05375E-05 | None | None | None | None | N | None | 1.33522E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18686E-05 | 2.19631E-05 | 0 |
| P/R | 20921 |
Fn3-39 |
58 | rs2154183465 |
0.174 | None | 0.968 | N | 0.605 | 0.215 | 0.3349148499 | gnomAD-4.0.0 | 3.18856E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58722E-05 | None | 0 | 0 | 0 | 0 | 0 |
| P/S | 20921 |
Fn3-39 |
58 | rs935268567 |
0.1152 | None | 0.811 | N | 0.485 | 0.081 | 0.242244723065 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| P/S | 20921 |
Fn3-39 |
58 | rs935268567 |
0.1152 | None | 0.811 | N | 0.485 | 0.081 | 0.242244723065 | gnomAD-4.0.0 | 1.86062E-06 | None | None | None | None | N | None | 1.33568E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.6958E-06 | 0 | 0 |
| P/T | 20921 |
Fn3-39 |
58 | None | 0.0875 | -1.559 | 0.103 | N | 0.348 | 0.067 | 0.146414634003 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14732E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 20921 |
Fn3-39 |
58 | None | 0.0875 | -1.559 | 0.103 | N | 0.348 | 0.067 | 0.146414634003 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.79846E-04 |
| P/T | 20921 |
Fn3-39 |
58 | None | 0.0875 | -1.559 | 0.103 | N | 0.348 | 0.067 | 0.146414634003 | gnomAD-4.0.0 | 5.58187E-06 | None | None | None | None | N | None | 1.33568E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47902E-07 | 0 | 1.12197E-04 |
| K/E | 21128 |
Fn3-41 |
65 | rs2049409571 |
0.1688 | None | 0.014 | N | 0.329 | 0.06 | 0.163833314356 | gnomAD-4.0.0 | 2.05362E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69926E-06 | 0 | 0 |
| T/I | 21323 |
Fn3-42 |
58 | None | 0.2003 | None | 0.987 | N | 0.631 | 0.324 | 0.365892764245 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/Q | 21424 |
Fn3-43 |
59 | None | 0.325 | None | 0.999 | N | 0.785 | 0.453 | 0.783626635962 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 21424 |
Fn3-43 |
59 | None | 0.1744 | None | 0.992 | N | 0.499 | 0.318 | 0.600208187352 | gnomAD-4.0.0 | 1.36889E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99735E-07 | 0 | 1.65733E-05 |
| T/I | 21617 |
Fn3-44 |
59 | rs1455243319 |
0.4639 | 0.085 | 0.978 | N | 0.757 | 0.505 | 0.428630128466 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| T/I | 21617 |
Fn3-44 |
59 | rs1455243319 |
0.4639 | 0.085 | 0.978 | N | 0.757 | 0.505 | 0.428630128466 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 21617 |
Fn3-44 |
59 | rs1455243319 |
0.4639 | 0.085 | 0.978 | N | 0.757 | 0.505 | 0.428630128466 | gnomAD-4.0.0 | 6.57704E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47106E-05 | 0 | 0 |
| E/K | 21817 |
Fn3-46 |
61 | rs751947173 |
0.4774 | -0.091 | 0.999 | N | 0.617 | 0.438 | 0.32714864917 | gnomAD-2.1.1 | 1.08E-05 | None | None | None | None | N | None | 0 | 8.54E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 21817 |
Fn3-46 |
61 | rs751947173 |
0.4774 | -0.091 | 0.999 | N | 0.617 | 0.438 | 0.32714864917 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 21817 |
Fn3-46 |
61 | rs751947173 |
0.4774 | -0.091 | 0.999 | N | 0.617 | 0.438 | 0.32714864917 | gnomAD-4.0.0 | 2.48111E-06 | None | None | None | None | N | None | 0 | 3.34046E-05 | None | 0 | 0 | None | 0 | 0 | 1.69612E-06 | 0 | 0 |
| T/I | 22013 |
Fn3-47 |
58 | rs2047988324 |
0.3737 | None | 0.999 | N | 0.733 | 0.439 | 0.491996647052 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 22013 |
Fn3-47 |
58 | rs2047988324 |
0.3737 | None | 0.999 | N | 0.733 | 0.439 | 0.491996647052 | gnomAD-4.0.0 | 3.84754E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.18608E-06 | 0 | 0 |
| R/K | 22113 |
Fn3-48 |
59 | rs748719400 |
0.2637 | -0.37 | 0.997 | N | 0.552 | 0.258 | 0.233785782151 | gnomAD-4.0.0 | 1.59217E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86044E-06 | 0 | 0 |
| T/N | 22215 |
Fn3-49 |
60 | None | 0.1639 | None | 0.998 | N | 0.623 | 0.377 | 0.354610295913 | gnomAD-4.0.0 | 1.59361E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43345E-05 | 0 |
| L/P | 22506 |
Fn3-51 |
56 | None | 0.1948 | None | 0.773 | N | 0.591 | 0.338 | 0.561523483268 | gnomAD-4.0.0 | 1.59225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86015E-06 | 0 | 0 |
| T/A | 22701 |
Fn3-52 |
59 | rs536702948 |
0.1443 | -0.74 | 0.996 | N | 0.455 | 0.448 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| T/A | 22701 |
Fn3-52 |
59 | rs536702948 |
0.1443 | -0.74 | 0.996 | N | 0.455 | 0.448 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 22701 |
Fn3-52 |
59 | rs536702948 |
0.1443 | -0.74 | 0.996 | N | 0.455 | 0.448 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| T/A | 22701 |
Fn3-52 |
59 | rs536702948 |
0.1443 | -0.74 | 0.996 | N | 0.455 | 0.448 | None | gnomAD-4.0.0 | 9.91816E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35654E-05 | 0 | 0 |
| R/G | 22801 |
Fn3-53 |
59 | rs1465137040 |
0.2195 | -1.389 | 0.117 | N | 0.453 | 0.172 | 0.377976839388 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| R/G | 22801 |
Fn3-53 |
59 | rs1465137040 |
0.2195 | -1.389 | 0.117 | N | 0.453 | 0.172 | 0.377976839388 | gnomAD-4.0.0 | 1.59241E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86049E-06 | 0 | 0 |
| C/Y | 22899 |
Fn3-54 |
59 | None | 0.3533 | None | 1.0 | N | 0.783 | 0.367 | 0.739227818891 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| C/G | 23097 |
Fn3-55 |
58 | rs1165725715 |
0.214 | -2.221 | 1.0 | N | 0.766 | 0.546 | 0.80155032981 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| C/G | 23097 |
Fn3-55 |
58 | rs1165725715 |
0.214 | -2.221 | 1.0 | N | 0.766 | 0.546 | 0.80155032981 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/G | 23097 |
Fn3-55 |
58 | rs1165725715 |
0.214 | -2.221 | 1.0 | N | 0.766 | 0.546 | 0.80155032981 | gnomAD-4.0.0 | 3.7189E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.0865E-06 | 0 | 0 |
| C/R | 23097 |
Fn3-55 |
58 | rs1165725715 |
0.4211 | None | 1.0 | N | 0.798 | 0.53 | 0.778074337641 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| C/R | 23097 |
Fn3-55 |
58 | rs1165725715 |
0.4211 | None | 1.0 | N | 0.798 | 0.53 | 0.778074337641 | gnomAD-4.0.0 | 1.61152E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.20415E-05 | 0 | 0 |
| L/F | 23197 |
Fn3-56 |
59 | rs2046500337 |
0.4864 | None | 0.994 | N | 0.742 | 0.206 | 0.521122704751 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 1.90042E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/S | 23588 |
Fn3-59 |
57 | None | 0.3964 | None | 1.0 | N | 0.761 | 0.531 | 0.675944014053 | gnomAD-4.0.0 | 4.79008E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39724E-06 | 0 | 1.65684E-05 |
| T/I | 23784 |
Fn3-60 |
59 | None | 0.7979 | None | 1.0 | N | 0.743 | 0.481 | 0.449956787536 | gnomAD-4.0.0 | 1.59524E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78211E-05 | None | 0 | 0 | 0 | 0 | 0 |
| N/K | 23884 |
Fn3-61 |
59 | None | 0.2932 | None | 0.977 | N | 0.543 | 0.296 | 0.234412748748 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| N/D | 23982 |
Fn3-62 |
59 | rs199755820 |
0.1653 | -0.958 | 0.625 | N | 0.452 | 0.247 | 0.117506650769 | gnomAD-2.1.1 | 8.23E-05 | None | None | None | None | N | None | 0 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 2.39789E-04 | 1.17723E-04 | 1.40607E-04 |
| N/D | 23982 |
Fn3-62 |
59 | rs199755820 |
0.1653 | -0.958 | 0.625 | N | 0.452 | 0.247 | 0.117506650769 | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 2.82433E-04 | 0 | 1.17661E-04 | 0 | 0 |
| N/D | 23982 |
Fn3-62 |
59 | rs199755820 |
0.1653 | -0.958 | 0.625 | N | 0.452 | 0.247 | 0.117506650769 | gnomAD-4.0.0 | 1.05367E-04 | None | None | None | None | N | None | 0 | 1.66728E-05 | None | 0 | 0 | None | 3.43664E-04 | 0 | 1.1868E-04 | 0 | 1.12108E-04 |
| L/F | 24280 |
Fn3-64 |
59 | None | 0.3501 | None | 1.0 | N | 0.681 | 0.263 | 0.464183351471 | gnomAD-4.0.0 | 1.65939E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.79799E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 24382 |
Fn3-65 |
60 | None | 0.1586 | None | 0.999 | N | 0.579 | 0.351 | 0.342168650903 | gnomAD-4.0.0 | 1.59273E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.88352E-05 | 0 | 0 | 0 | 0 |
| T/A | 24866 |
Fn3-68 |
59 | rs199784966 |
0.2724 | -0.9 | 0.999 | N | 0.501 | 0.448 | None | gnomAD-2.1.1 | 2.04577E-04 | None | None | None | None | N | None | 2.27574E-03 | 2.84E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.41123E-04 |
| T/A | 24866 |
Fn3-68 |
59 | rs199784966 |
0.2724 | -0.9 | 0.999 | N | 0.501 | 0.448 | None | gnomAD-3.1.2 | 5.85126E-04 | None | None | None | None | N | None | 2.12355E-03 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 24866 |
Fn3-68 |
59 | rs199784966 |
0.2724 | -0.9 | 0.999 | N | 0.501 | 0.448 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/A | 24866 |
Fn3-68 |
59 | rs199784966 |
0.2724 | -0.9 | 0.999 | N | 0.501 | 0.448 | None | gnomAD-4.0.0 | 1.10953E-04 | None | None | None | None | N | None | 2.27957E-03 | 3.33489E-05 | None | 0 | 0 | None | 0 | 1.65125E-04 | 1.69552E-06 | 0 | 4.80369E-05 |
| T/K | 24866 |
Fn3-68 |
59 | None | 0.6182 | None | 1.0 | N | 0.751 | 0.5 | 0.487277728379 | gnomAD-4.0.0 | 2.05348E-06 | None | None | None | None | N | None | 2.98918E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.7994E-06 | 0 | 0 |
| T/R | 24866 |
Fn3-68 |
59 | rs940915212 |
0.5507 | None | 1.0 | N | 0.765 | 0.508 | 0.62347134366 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 0 | 4.59016E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| T/R | 24866 |
Fn3-68 |
59 | rs940915212 |
0.5507 | None | 1.0 | N | 0.765 | 0.508 | 0.62347134366 | gnomAD-4.0.0 | 7.43989E-06 | None | None | None | None | N | None | 0 | 1.5017E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.806E-05 |
| T/N | 24966 |
Fn3-69 |
59 | None | 0.1018 | None | 0.204 | N | 0.385 | 0.25 | 0.239305524855 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 25064 |
Fn3-70 |
59 | rs893428451 |
0.1363 | -0.816 | 0.656 | N | 0.423 | 0.297 | 0.228597637076 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| T/A | 25064 |
Fn3-70 |
59 | rs893428451 |
0.1363 | -0.816 | 0.656 | N | 0.423 | 0.297 | 0.228597637076 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/A | 25064 |
Fn3-70 |
59 | rs893428451 |
0.1363 | -0.816 | 0.656 | N | 0.423 | 0.297 | 0.228597637076 | gnomAD-4.0.0 | 2.85118E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.81481E-05 | 0 | 1.60149E-05 |
| T/P | 25064 |
Fn3-70 |
59 | None | 0.2012 | None | 0.99 | N | 0.619 | 0.519 | 0.480724696071 | gnomAD-4.0.0 | 6.84284E-07 | None | None | None | None | N | None | 0 | 2.23614E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/F | 25362 |
Fn3-72 |
59 | None | 0.5017 | None | 0.988 | N | 0.754 | 0.352 | 0.452640719197 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| L/V | 25362 |
Fn3-72 |
59 | rs1409589701 |
0.1913 | None | 0.919 | N | 0.565 | 0.165 | 0.300110245524 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93874E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 25362 |
Fn3-72 |
59 | rs1409589701 |
0.1913 | None | 0.919 | N | 0.565 | 0.165 | 0.300110245524 | gnomAD-4.0.0 | 6.58354E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93874E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/R | 25464 |
Fn3-73 |
60 | None | 0.1396 | None | 0.997 | N | 0.663 | 0.36 | 0.478755181577 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/S | 25658 |
Fn3-74 |
58 | None | 0.0842 | None | None | N | 0.161 | 0.106 | 0.0401082797425 | gnomAD-4.0.0 | 1.59233E-06 | None | None | None | None | N | None | 0 | 2.2876E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 25754 |
Fn3-75 |
57 | rs1369560200 |
0.2082 | -0.739 | 0.998 | N | 0.801 | 0.443 | 0.801626560535 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 2.87687E-04 | 0 | 0 |
| L/P | 25754 |
Fn3-75 |
57 | rs1369560200 |
0.2082 | -0.739 | 0.998 | N | 0.801 | 0.443 | 0.801626560535 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/P | 25754 |
Fn3-75 |
57 | rs1369560200 |
0.2082 | -0.739 | 0.998 | N | 0.801 | 0.443 | 0.801626560535 | gnomAD-4.0.0 | 6.57557E-06 | None | None | None | None | N | None | 2.41336E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 26048 |
Fn3-77 |
59 | None | 0.1567 | None | 0.472 | N | 0.451 | 0.155 | 0.235664433957 | gnomAD-4.0.0 | 1.59194E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85953E-06 | 0 | 0 |
| T/P | 26048 |
Fn3-77 |
59 | rs794729508 |
0.2921 | -0.003 | 0.979 | N | 0.516 | 0.376 | 0.371344866733 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 1.14863E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/P | 26048 |
Fn3-77 |
59 | rs794729508 |
0.2921 | -0.003 | 0.979 | N | 0.516 | 0.376 | 0.371344866733 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 26048 |
Fn3-77 |
59 | rs794729508 |
0.2921 | -0.003 | 0.979 | N | 0.516 | 0.376 | 0.371344866733 | gnomAD-4.0.0 | 2.56329E-06 | None | None | None | None | I | None | 3.3849E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 26048 |
Fn3-77 |
59 | rs1383437099 |
0.1908 | -1.365 | 0.684 | N | 0.539 | 0.255 | 0.257292322809 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/S | 26048 |
Fn3-77 |
59 | rs1383437099 |
0.1908 | -1.365 | 0.684 | N | 0.539 | 0.255 | 0.257292322809 | gnomAD-4.0.0 | 1.5919E-06 | None | None | None | None | I | None | 0 | 2.28728E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 26546 |
Fn3-81 |
60 | rs775053902 |
0.1049 | -0.491 | 0.928 | N | 0.522 | 0.322 | 0.181679512989 | gnomAD-2.1.1 | 2.42E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 4.45E-05 | 0 |
| T/A | 26546 |
Fn3-81 |
60 | rs775053902 |
0.1049 | -0.491 | 0.928 | N | 0.522 | 0.322 | 0.181679512989 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| T/A | 26546 |
Fn3-81 |
60 | rs775053902 |
0.1049 | -0.491 | 0.928 | N | 0.522 | 0.322 | 0.181679512989 | gnomAD-4.0.0 | 5.45432E-05 | None | None | None | None | N | None | 0 | 5.00267E-05 | None | 0 | 0 | None | 0 | 0 | 7.12058E-05 | 0 | 1.60154E-05 |
| C/S | 26836 |
Fn3-83 |
57 | None | 0.3568 | None | 0.961 | N | 0.469 | 0.412 | 0.552822141497 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/Y | 26836 |
Fn3-83 |
57 | rs893506951 |
0.4616 | None | 0.999 | N | 0.694 | 0.368 | 0.661710244528 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/Y | 26836 |
Fn3-83 |
57 | rs893506951 |
0.4616 | None | 0.999 | N | 0.694 | 0.368 | 0.661710244528 | gnomAD-4.0.0 | 6.57575E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47098E-05 | 0 | 0 |
| T/A | 27030 |
Fn3-84 |
59 | None | 0.2287 | None | 0.958 | N | 0.438 | 0.401 | 0.241664281697 | gnomAD-4.0.0 | 1.59164E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85901E-06 | 0 | 0 |
| T/I | 27030 |
Fn3-84 |
59 | rs1705177542 |
0.8411 | None | 0.976 | N | 0.574 | 0.449 | 0.471456661759 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 27030 |
Fn3-84 |
59 | rs1705177542 |
0.8411 | None | 0.976 | N | 0.574 | 0.449 | 0.471456661759 | gnomAD-4.0.0 | 1.85932E-06 | None | None | None | None | N | None | 0 | 1.66767E-05 | None | 0 | 0 | None | 0 | 0 | 1.69537E-06 | 0 | 0 |
| T/K | 27030 |
Fn3-84 |
59 | None | 0.5516 | None | 0.994 | N | 0.647 | 0.497 | 0.480274617672 | gnomAD-4.0.0 | 1.36856E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99548E-07 | 1.15972E-05 | 0 |
| T/R | 27030 |
Fn3-84 |
59 | rs1705177542 |
0.4858 | None | 0.994 | N | 0.709 | 0.454 | 0.606288219858 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| T/R | 27030 |
Fn3-84 |
59 | rs1705177542 |
0.4858 | None | 0.994 | N | 0.709 | 0.454 | 0.606288219858 | gnomAD-4.0.0 | 6.57436E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| T/A | 27130 |
Fn3-85 |
59 | rs1458266524 |
0.1357 | -0.748 | 0.058 | N | 0.281 | 0.176 | 0.144782658237 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.98E-06 | 0 |
| T/A | 27130 |
Fn3-85 |
59 | rs1458266524 |
0.1357 | -0.748 | 0.058 | N | 0.281 | 0.176 | 0.144782658237 | gnomAD-4.0.0 | 3.18701E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72253E-06 | 0 | 0 |
| T/I | 27130 |
Fn3-85 |
59 | rs757768218 |
0.3915 | 0.329 | 0.698 | N | 0.485 | 0.421 | 0.425148423609 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| T/I | 27130 |
Fn3-85 |
59 | rs757768218 |
0.3915 | 0.329 | 0.698 | N | 0.485 | 0.421 | 0.425148423609 | gnomAD-4.0.0 | 6.16132E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59899E-06 | 0 | 8.2905E-05 |
| L/P | 27527 |
Fn3-88 |
59 | rs202169004 |
0.6602 | -0.983 | 1.0 | N | 0.815 | 0.427 | 0.787995792498 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| L/P | 27527 |
Fn3-88 |
59 | rs202169004 |
0.6602 | -0.983 | 1.0 | N | 0.815 | 0.427 | 0.787995792498 | gnomAD-4.0.0 | 1.43215E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.28671E-05 | 1.43271E-05 | 0 |
| T/A | 27823 |
Fn3-90 |
58 | rs940216066 |
0.0823 | -0.809 | 0.001 | N | 0.297 | 0.325 | 0.283761946502 | gnomAD-2.1.1 | 4.28E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.25E-06 | 0 |
| T/A | 27823 |
Fn3-90 |
58 | rs940216066 |
0.0823 | -0.809 | 0.001 | N | 0.297 | 0.325 | 0.283761946502 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 27823 |
Fn3-90 |
58 | rs940216066 |
0.0823 | -0.809 | 0.001 | N | 0.297 | 0.325 | 0.283761946502 | gnomAD-4.0.0 | 3.9291E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.28905E-06 | 0 | 0 |
| T/I | 28112 |
Fn3-92 |
58 | rs1429490203 |
0.7126 | 0.062 | 0.994 | N | 0.729 | 0.475 | 0.467839254973 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/I | 28112 |
Fn3-92 |
58 | rs1429490203 |
0.7126 | 0.062 | 0.994 | N | 0.729 | 0.475 | 0.467839254973 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 28112 |
Fn3-92 |
58 | rs1429490203 |
0.7126 | 0.062 | 0.994 | N | 0.729 | 0.475 | 0.467839254973 | gnomAD-4.0.0 | 3.71853E-06 | None | None | None | None | N | None | 1.33479E-05 | 1.66733E-05 | None | 0 | 0 | None | 0 | 0 | 2.5429E-06 | 0 | 1.60123E-05 |
| T/K | 28112 |
Fn3-92 |
58 | None | 0.4076 | None | 0.988 | N | 0.654 | 0.484 | 0.408714661073 | gnomAD-4.0.0 | 6.84286E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65673E-05 |
| T/I | 28212 |
Fn3-93 |
59 | rs527851457 |
0.3566 | 0.165 | 0.97 | D | 0.636 | 0.406 | 0.530803083455 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | I | None | 0 | 1.45003E-04 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/I | 28212 |
Fn3-93 |
59 | rs527851457 |
0.3566 | 0.165 | 0.97 | D | 0.636 | 0.406 | 0.530803083455 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 1.31027E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 28212 |
Fn3-93 |
59 | rs527851457 |
0.3566 | 0.165 | 0.97 | D | 0.636 | 0.406 | 0.530803083455 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/I | 28212 |
Fn3-93 |
59 | rs527851457 |
0.3566 | 0.165 | 0.97 | D | 0.636 | 0.406 | 0.530803083455 | gnomAD-4.0.0 | 1.0249E-05 | None | None | None | None | I | None | 0 | 1.01667E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 2.68068E-05 | 0 |
| T/P | 28212 |
Fn3-93 |
59 | None | 0.2045 | None | 0.99 | N | 0.637 | 0.467 | 0.510642626009 | gnomAD-4.0.0 | 1.59157E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85871E-06 | 0 | 0 |
| T/S | 28212 |
Fn3-93 |
59 | None | 0.1368 | None | 0.822 | N | 0.49 | 0.327 | 0.317378411342 | gnomAD-4.0.0 | 1.59156E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85873E-06 | 0 | 0 |
| T/I | 28310 |
Fn3-94 |
59 | rs765062342 |
0.4313 | 0.505 | 0.994 | N | 0.777 | 0.439 | 0.523082183605 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 0 | 0 |
| T/I | 28310 |
Fn3-94 |
59 | rs765062342 |
0.4313 | 0.505 | 0.994 | N | 0.777 | 0.439 | 0.523082183605 | gnomAD-4.0.0 | 3.18382E-06 | None | None | None | None | N | None | 0 | 2.28686E-05 | None | 0 | 2.77824E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 28998 |
Fn3-99 |
57 | None | 0.0822 | None | 0.775 | N | 0.4 | 0.373 | 0.233785782151 | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85802E-06 | 0 | 0 |
| T/I | 28998 |
Fn3-99 |
57 | rs1206763274 |
0.1674 | None | 0.789 | N | 0.36 | 0.303 | 0.390531646278 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/N | 29195 |
Fn3-100 |
59 | rs751134822 |
0.0847 | -1.055 | None | N | 0.231 | 0.186 | 0.223847106136 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/N | 29195 |
Fn3-100 |
59 | rs751134822 |
0.0847 | -1.055 | None | N | 0.231 | 0.186 | 0.223847106136 | gnomAD-4.0.0 | 2.0525E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.47818E-05 | 0 |
| T/S | 29295 |
Fn3-101 |
59 | None | 0.1327 | None | 0.103 | N | 0.344 | 0.354 | 0.178374595973 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| T/I | 29393 |
Fn3-102 |
59 | rs746109021 |
0.3733 | 0.31 | 0.994 | N | 0.527 | 0.39 | 0.399740851666 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 29393 |
Fn3-102 |
59 | rs746109021 |
0.3733 | 0.31 | 0.994 | N | 0.527 | 0.39 | 0.399740851666 | gnomAD-4.0.0 | 1.59131E-06 | None | None | None | None | N | None | 0 | 2.28624E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 29393 |
Fn3-102 |
59 | rs746109021 |
0.158 | -1.178 | 0.775 | N | 0.571 | 0.242 | 0.156986980423 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/S | 29393 |
Fn3-102 |
59 | rs746109021 |
0.158 | -1.178 | 0.775 | N | 0.571 | 0.242 | 0.156986980423 | gnomAD-4.0.0 | 1.59131E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43283E-05 | 0 |
| C/Y | 29591 |
Fn3-103 |
59 | None | 0.4472 | None | 0.004 | N | 0.5 | 0.353 | 0.62347134366 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/N | 29691 |
Fn3-104 |
59 | rs794729525 |
0.2306 | None | 1.0 | N | 0.669 | 0.371 | 0.390842690916 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 29691 |
Fn3-104 |
59 | rs794729525 |
0.2306 | None | 1.0 | N | 0.669 | 0.371 | 0.390842690916 | gnomAD-4.0.0 | 1.1155E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52567E-05 | 0 | 0 |
| T/I | 29990 |
Fn3-106 |
58 | None | 0.2335 | None | 0.89 | N | 0.562 | 0.338 | 0.41518383557 | gnomAD-4.0.0 | 6.84257E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| T/K | 29990 |
Fn3-106 |
58 | rs1699983035 |
0.2636 | None | 0.89 | N | 0.562 | 0.366 | 0.402899589544 | gnomAD-4.0.0 | 1.36851E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79891E-06 | 0 | 0 |
| C/R | 30086 |
Fn3-107 |
57 | rs372568082 |
0.462 | -0.579 | 0.999 | N | 0.707 | 0.502 | None | gnomAD-2.1.1 | 2.14E-05 | None | None | None | None | N | None | 1.65303E-04 | 0 | None | 0 | 1.02564E-04 | None | 0 | None | 0 | 0 | 0 |
| C/R | 30086 |
Fn3-107 |
57 | rs372568082 |
0.462 | -0.579 | 0.999 | N | 0.707 | 0.502 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/R | 30086 |
Fn3-107 |
57 | rs372568082 |
0.462 | -0.579 | 0.999 | N | 0.707 | 0.502 | None | gnomAD-4.0.0 | 8.96638E-06 | None | None | None | None | N | None | 1.01468E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39258E-06 | 0 | 0 |
| C/S | 30086 |
Fn3-107 |
57 | rs372568082 |
0.3202 | -1.431 | 0.997 | N | 0.526 | 0.431 | 0.583804852878 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| C/S | 30086 |
Fn3-107 |
57 | rs372568082 |
0.3202 | -1.431 | 0.997 | N | 0.526 | 0.431 | 0.583804852878 | gnomAD-4.0.0 | 4.7731E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57329E-06 | 0 | 0 |
| C/Y | 30086 |
Fn3-107 |
57 | rs1699883953 |
0.544 | None | 0.999 | N | 0.653 | 0.324 | 0.650169478884 | gnomAD-4.0.0 | 2.05249E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69825E-06 | 0 | 0 |
| T/M | 30282 |
Fn3-108 |
59 | rs756769026 |
0.1573 | -0.184 | 1.0 | N | 0.75 | 0.489 | 0.562617508568 | gnomAD-2.1.1 | 3.21E-05 | None | None | None | None | N | None | 8.27E-05 | 1.41507E-04 | None | 0 | 5.13E-05 | None | 0 | None | 0 | 7.81E-06 | 0 |
| T/M | 30282 |
Fn3-108 |
59 | rs756769026 |
0.1573 | -0.184 | 1.0 | N | 0.75 | 0.489 | 0.562617508568 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| T/M | 30282 |
Fn3-108 |
59 | rs756769026 |
0.1573 | -0.184 | 1.0 | N | 0.75 | 0.489 | 0.562617508568 | gnomAD-4.0.0 | 2.47899E-05 | None | None | None | None | N | None | 6.67592E-05 | 8.33639E-05 | None | 0 | 2.22846E-05 | None | 0 | 0 | 2.03431E-05 | 1.09844E-05 | 6.40533E-05 |
| T/R | 30282 |
Fn3-108 |
59 | None | 0.3132 | None | 1.0 | N | 0.709 | 0.478 | 0.517432700143 | gnomAD-4.0.0 | 6.84258E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99496E-07 | 0 | 0 |
| R/G | 30382 |
Fn3-109 |
59 | None | 0.2426 | None | 0.994 | N | 0.597 | 0.321 | 0.41958645093 | gnomAD-4.0.0 | 2.40085E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62524E-06 | 0 | 0 |
| R/I | 30382 |
Fn3-109 |
59 | rs1699529751 |
0.349 | None | 0.999 | N | 0.733 | 0.316 | 0.469000238065 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/I | 30382 |
Fn3-109 |
59 | rs1699529751 |
0.349 | None | 0.999 | N | 0.733 | 0.316 | 0.469000238065 | gnomAD-4.0.0 | 2.02989E-06 | None | None | None | None | N | None | 1.74734E-05 | 6.15233E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/S | 30382 |
Fn3-109 |
59 | rs771142882 |
0.5195 | -1.67 | 0.989 | N | 0.585 | 0.31 | 0.258779203287 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/S | 30382 |
Fn3-109 |
59 | rs771142882 |
0.5195 | -1.67 | 0.989 | N | 0.585 | 0.31 | 0.258779203287 | gnomAD-4.0.0 | 1.59121E-06 | None | None | None | None | N | None | 5.65483E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| C/S | 30479 |
Fn3-110 |
58 | rs1248613242 |
0.4211 | -1.773 | 0.828 | N | 0.463 | 0.237 | 0.569599524359 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| C/S | 30479 |
Fn3-110 |
58 | rs1248613242 |
0.4211 | -1.773 | 0.828 | N | 0.463 | 0.237 | 0.569599524359 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| C/S | 30479 |
Fn3-110 |
58 | rs1248613242 |
0.4211 | -1.773 | 0.828 | N | 0.463 | 0.237 | 0.569599524359 | gnomAD-4.0.0 | 1.2397E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69544E-06 | 0 | 0 |
| C/Y | 30479 |
Fn3-110 |
58 | None | 0.4868 | None | 0.998 | N | 0.553 | 0.366 | 0.71479990609 | gnomAD-4.0.0 | 2.73751E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59836E-06 | 0 | 0 |
| T/R | 30778 |
Fn3-112 |
60 | rs201019681 |
0.2555 | -0.498 | 0.81 | N | 0.548 | 0.218 | None | gnomAD-2.1.1 | 8.55E-05 | None | None | None | None | N | None | 4.13E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 1.59859E-04 | 1.40198E-04 | 0 |
| T/R | 30778 |
Fn3-112 |
60 | rs201019681 |
0.2555 | -0.498 | 0.81 | N | 0.548 | 0.218 | None | gnomAD-3.1.2 | 1.18307E-04 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 1.88573E-04 | 0 | 2.05804E-04 | 0 | 0 |
| T/R | 30778 |
Fn3-112 |
60 | rs201019681 |
0.2555 | -0.498 | 0.81 | N | 0.548 | 0.218 | None | gnomAD-4.0.0 | 2.29277E-04 | None | None | None | None | N | None | 2.67008E-05 | 3.33356E-05 | None | 0 | 0 | None | 1.09372E-04 | 0 | 2.98346E-04 | 0 | 1.12072E-04 |
| T/A | 31366 |
Fn3-116 |
59 | rs1369343605 |
0.1484 | -0.706 | 0.928 | N | 0.451 | 0.487 | 0.322230723748 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| T/A | 31366 |
Fn3-116 |
59 | rs1369343605 |
0.1484 | -0.706 | 0.928 | N | 0.451 | 0.487 | 0.322230723748 | gnomAD-4.0.0 | 2.05276E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69842E-06 | 0 | 0 |
| T/I | 31366 |
Fn3-116 |
59 | None | 0.5775 | None | 0.085 | N | 0.356 | 0.438 | 0.286081765059 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/P | 31366 |
Fn3-116 |
59 | None | 0.0913 | None | 0.996 | N | 0.729 | 0.475 | 0.379881503574 | gnomAD-4.0.0 | 6.84255E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87357E-05 | 0 | 0 | 0 | 0 |
| C/G | 31466 |
Fn3-117 |
59 | rs1697549166 |
0.1423 | None | 1.0 | N | 0.779 | 0.501 | 0.816487136085 | gnomAD-4.0.0 | 1.59128E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85847E-06 | 0 | 0 |
| N/S | 31567 |
Fn3-118 |
62 | rs886042885 |
0.0973 | -0.94 | 0.992 | N | 0.499 | 0.192 | 0.152612264143 | gnomAD-2.1.1 | 4.29E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.62E-05 | 0 |
| N/S | 31567 |
Fn3-118 |
62 | rs886042885 |
0.0973 | -0.94 | 0.992 | N | 0.499 | 0.192 | 0.152612264143 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| N/S | 31567 |
Fn3-118 |
62 | rs886042885 |
0.0973 | -0.94 | 0.992 | N | 0.499 | 0.192 | 0.152612264143 | gnomAD-4.0.0 | 5.51569E-05 | None | None | None | None | N | None | 4.00759E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.12012E-05 | 0 | 3.20297E-05 |
| T/A | 31866 |
Fn3-120 |
60 | rs1559138864 |
0.1428 | -0.692 | 0.999 | N | 0.575 | 0.532 | 0.290222751274 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/A | 31866 |
Fn3-120 |
60 | rs1559138864 |
0.1428 | -0.692 | 0.999 | N | 0.575 | 0.532 | 0.290222751274 | gnomAD-4.0.0 | 3.1831E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86574E-05 | 0 |
| T/I | 31968 |
Fn3-121 |
60 | None | 0.2075 | None | 0.029 | N | 0.462 | 0.199 | 0.165133752707 | gnomAD-4.0.0 | 1.59144E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85873E-06 | 0 | 0 |
| T/N | 31968 |
Fn3-121 |
60 | rs1696025684 |
0.0726 | None | None | N | 0.135 | 0.139 | 0.124217242631 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 31968 |
Fn3-121 |
60 | rs1696025684 |
0.0726 | None | None | N | 0.135 | 0.139 | 0.124217242631 | gnomAD-4.0.0 | 2.56251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39338E-06 | 0 | 2.84495E-05 |
| L/V | 32260 |
Fn3-123 |
59 | rs1695466303 |
0.1101 | None | 0.801 | N | 0.401 | 0.161 | 0.408714661073 | gnomAD-4.0.0 | 1.36841E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79893E-06 | 0 | 0 |
| R/G | 32658 |
Fn3-126 |
59 | None | 0.3285 | None | 0.954 | N | 0.493 | 0.348 | 0.46614307118 | gnomAD-4.0.0 | 6.84191E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99467E-07 | 0 | 0 |
| R/Q | 32658 |
Fn3-126 |
59 | rs769581585 |
0.1334 | -0.455 | 0.998 | N | 0.561 | 0.35 | 0.159798565429 | gnomAD-2.1.1 | 4.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.33816E-04 | None | 9.8E-05 | None | 0 | 8.87E-06 | 0 |
| R/Q | 32658 |
Fn3-126 |
59 | rs769581585 |
0.1334 | -0.455 | 0.998 | N | 0.561 | 0.35 | 0.159798565429 | gnomAD-4.0.0 | 1.36839E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.25945E-04 | None | 0 | 0 | 1.79894E-06 | 1.50711E-04 | 0 |
| T/I | 32853 |
Fn3-127 |
59 | rs746181929 |
0.3548 | -0.03 | 0.999 | D | 0.759 | 0.525 | 0.650937406085 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| T/I | 32853 |
Fn3-127 |
59 | rs746181929 |
0.3548 | -0.03 | 0.999 | D | 0.759 | 0.525 | 0.650937406085 | gnomAD-4.0.0 | 4.10519E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49739E-06 | 1.15931E-05 | 0 |
| T/A | 32955 |
Fn3-128 |
60 | None | 0.223 | None | 0.999 | N | 0.509 | 0.403 | 0.351830644314 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.50964E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 33056 |
Fn3-129 |
59 | rs1692876127 |
0.3835 | None | 0.117 | N | 0.478 | 0.113 | 0.0666544352282 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| K/N | 33056 |
Fn3-129 |
59 | rs1692876127 |
0.3835 | None | 0.117 | N | 0.478 | 0.113 | 0.0666544352282 | gnomAD-4.0.0 | 6.57341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| T/N | 33450 |
Fn3-131 |
59 | rs1691516796 |
0.2291 | None | 1.0 | N | 0.751 | 0.39 | 0.457377140028 | gnomAD-4.0.0 | 1.36857E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.799E-06 | 0 | 0 |
| T/R | 33745 |
Fn3-132 |
57 | None | 0.2222 | None | 0.999 | N | 0.622 | 0.401 | 0.591849201417 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.