Structural position:
- Domain Type: Fn3
- Aligned Position: 96
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G/A | 15720 |
Fn3-1 |
64 | None | 0.3371 | None | 0.984 | D | 0.587 | 0.439 | 0.369682402691 | gnomAD-4.0.0 | 1.36922E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79976E-06 | 0 | 0 |
| D/N | 15822 |
Fn3-2 |
65 | None | 0.2005 | None | 1.0 | N | 0.655 | 0.365 | 0.327419511103 | gnomAD-4.0.0 | 2.05384E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69977E-06 | 0 | 0 |
| D/Y | 15822 |
Fn3-2 |
65 | rs1180743833 |
0.5942 | 0.145 | 1.0 | D | 0.653 | 0.495 | 0.739327834083 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 15822 |
Fn3-2 |
65 | rs1180743833 |
0.5942 | 0.145 | 1.0 | D | 0.653 | 0.495 | 0.739327834083 | gnomAD-4.0.0 | 2.73845E-06 | None | None | None | None | N | None | 2.99419E-05 | 0 | None | 0 | 7.57079E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/E | 15923 |
Fn3-3 |
65 | rs763457943 |
0.3861 | -0.082 | 0.777 | N | 0.48 | 0.402 | 0.276482976112 | gnomAD-2.1.1 | 1.24E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.69E-05 | None | 0 | 0 | 0 |
| G/E | 15923 |
Fn3-3 |
65 | rs763457943 |
0.3861 | -0.082 | 0.777 | N | 0.48 | 0.402 | 0.276482976112 | gnomAD-4.0.0 | 3.55191E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.34907E-05 | 0 |
| G/R | 15923 |
Fn3-3 |
65 | rs371943746 |
0.465 | -0.053 | 1.0 | D | 0.747 | 0.395 | 0.414150184683 | gnomAD-2.1.1 | 1.79236E-04 | None | None | None | None | N | None | 9.39227E-04 | 1.75316E-04 | None | 0 | 8.15E-05 | None | 0 | None | 0 | 1.47362E-04 | 0 |
| G/R | 15923 |
Fn3-3 |
65 | rs371943746 |
0.465 | -0.053 | 1.0 | D | 0.747 | 0.395 | 0.414150184683 | gnomAD-3.1.2 | 4.28291E-04 | None | None | None | None | N | None | 9.67118E-04 | 1.97057E-04 | 1.09649E-02 | 0 | 1.94856E-04 | None | 9.46E-05 | 0 | 1.32606E-04 | 0 | 4.78927E-04 |
| G/R | 15923 |
Fn3-3 |
65 | rs371943746 |
0.465 | -0.053 | 1.0 | D | 0.747 | 0.395 | 0.414150184683 | gnomAD-4.0.0 | 1.14647E-04 | None | None | None | None | N | None | 8.20744E-04 | 1.67863E-04 | None | 0 | 2.40662E-05 | None | 1.6456E-05 | 1.69205E-04 | 7.23915E-05 | 2.48231E-05 | 2.00743E-04 |
| D/G | 16118 |
Fn3-4 |
64 | rs376273101 |
0.1441 | -0.095 | 1.0 | N | 0.681 | 0.478 | 0.209622950755 | gnomAD-2.1.1 | 2.2911E-04 | None | None | None | None | N | None | 0 | 2.84E-05 | None | 0 | 2.95459E-03 | None | 1.96284E-04 | None | 0 | 0 | 0 |
| D/G | 16118 |
Fn3-4 |
64 | rs376273101 |
0.1441 | -0.095 | 1.0 | N | 0.681 | 0.478 | 0.209622950755 | gnomAD-3.1.2 | 1.58007E-04 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 3.5074E-03 | None | 0 | 0 | 0 | 8.285E-04 | 4.78011E-04 |
| D/G | 16118 |
Fn3-4 |
64 | rs376273101 |
0.1441 | -0.095 | 1.0 | N | 0.681 | 0.478 | 0.209622950755 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 2E-03 | 0 | None | None | None | 0 | None |
| D/G | 16118 |
Fn3-4 |
64 | rs376273101 |
0.1441 | -0.095 | 1.0 | N | 0.681 | 0.478 | 0.209622950755 | gnomAD-4.0.0 | 8.18837E-05 | None | None | None | None | N | None | 0 | 3.34024E-05 | None | 0 | 1.5009E-03 | None | 0 | 0 | 3.39338E-06 | 3.62677E-04 | 4.16693E-04 |
| D/V | 16118 |
Fn3-4 |
64 | None | 0.312 | None | 1.0 | D | 0.657 | 0.569 | 0.754712892271 | gnomAD-4.0.0 | 6.84916E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00203E-07 | 0 | 0 |
| G/S | 16218 |
Fn3-5 |
64 | rs566086846 |
0.1165 | -0.324 | 0.955 | D | 0.663 | 0.299 | 0.225215365344 | gnomAD-2.1.1 | 8.78E-06 | None | None | None | None | N | None | 0 | 3.11E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.77683E-04 |
| G/S | 16218 |
Fn3-5 |
64 | rs566086846 |
0.1165 | -0.324 | 0.955 | D | 0.663 | 0.299 | 0.225215365344 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 1.31423E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 16218 |
Fn3-5 |
64 | rs566086846 |
0.1165 | -0.324 | 0.955 | D | 0.663 | 0.299 | 0.225215365344 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| G/S | 16218 |
Fn3-5 |
64 | rs566086846 |
0.1165 | -0.324 | 0.955 | D | 0.663 | 0.299 | 0.225215365344 | gnomAD-4.0.0 | 5.22654E-06 | None | None | None | None | N | None | 0 | 5.2567E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.89001E-05 |
| K/R | 16414 |
Fn3-6 |
64 | rs1329659749 |
0.0834 | 0.272 | 0.801 | N | 0.395 | 0.149 | 0.28297238246 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| K/R | 16414 |
Fn3-6 |
64 | rs1329659749 |
0.0834 | 0.272 | 0.801 | N | 0.395 | 0.149 | 0.28297238246 | gnomAD-4.0.0 | 2.73877E-06 | None | None | None | None | N | None | 0 | 4.48209E-05 | None | 0 | 0 | None | 0 | 0 | 8.99826E-07 | 1.15974E-05 | 0 |
| G/D | 16514 |
Fn3-7 |
65 | rs776604541 |
0.823 | -0.422 | 1.0 | N | 0.753 | 0.534 | 0.328486982098 | gnomAD-4.0.0 | 1.60373E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.46469E-05 | 0 |
| G/V | 16614 |
Fn3-8 |
64 | None | 0.4658 | None | 0.999 | D | 0.797 | 0.442 | 0.585140355757 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| P/L | 16714 |
Fn3-9 |
64 | rs1309789816 |
0.8043 | 0.216 | 1.0 | N | 0.665 | 0.462 | 0.675375996808 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.95E-06 | 0 |
| P/L | 16714 |
Fn3-9 |
64 | rs1309789816 |
0.8043 | 0.216 | 1.0 | N | 0.665 | 0.462 | 0.675375996808 | gnomAD-4.0.0 | 2.05411E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69959E-06 | 0 | 0 |
| G/D | 16917 |
Fn3-11 |
66 | None | 0.3963 | None | 1.0 | N | 0.766 | 0.46 | 0.445107144611 | gnomAD-4.0.0 | 1.59294E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86131E-06 | 0 | 0 |
| D/G | 17110 |
Fn3-12 |
64 | None | 0.6101 | None | 1.0 | N | 0.686 | 0.503 | 0.27132560031 | gnomAD-4.0.0 | 1.59281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86153E-06 | 0 | 0 |
| D/Y | 17110 |
Fn3-12 |
64 | rs1176787179 |
0.7829 | 0.153 | 1.0 | N | 0.665 | 0.561 | 0.657092304468 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| D/Y | 17110 |
Fn3-12 |
64 | rs1176787179 |
0.7829 | 0.153 | 1.0 | N | 0.665 | 0.561 | 0.657092304468 | gnomAD-4.0.0 | 1.59281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86151E-06 | 0 | 0 |
| G/E | 17211 |
Fn3-13 |
65 | rs1447802224 |
0.2638 | None | 0.987 | N | 0.697 | 0.426 | 0.362960570912 | gnomAD-4.0.0 | 1.36901E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79967E-06 | 0 | 0 |
| G/V | 17211 |
Fn3-13 |
65 | rs1447802224 |
0.4323 | 0.038 | 0.997 | D | 0.741 | 0.482 | 0.490489133298 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| G/V | 17211 |
Fn3-13 |
65 | rs1447802224 |
0.4323 | 0.038 | 0.997 | D | 0.741 | 0.482 | 0.490489133298 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/V | 17211 |
Fn3-13 |
65 | rs1447802224 |
0.4323 | 0.038 | 0.997 | D | 0.741 | 0.482 | 0.490489133298 | gnomAD-4.0.0 | 4.34036E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.23155E-05 | None | 0 | 0 | 5.08813E-06 | 0 | 0 |
| G/C | 17533 |
Fn3-15 |
64 | rs2055410849 |
0.3646 | None | 1.0 | D | 0.722 | 0.66 | 0.723393103801 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/C | 17533 |
Fn3-15 |
64 | rs2055410849 |
0.3646 | None | 1.0 | D | 0.722 | 0.66 | 0.723393103801 | gnomAD-4.0.0 | 6.58111E-06 | None | None | None | None | N | None | 2.41546E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/C | 17826 |
Fn3-17 |
63 | None | 0.7478 | None | 1.0 | N | 0.765 | 0.55 | 0.766626682668 | gnomAD-4.0.0 | 1.59317E-06 | None | None | None | None | N | None | 0 | 2.28791E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 17826 |
Fn3-17 |
63 | rs1158023438 |
0.8683 | -0.113 | 1.0 | N | 0.743 | 0.469 | 0.253726318573 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/D | 17826 |
Fn3-17 |
63 | rs1158023438 |
0.8683 | -0.113 | 1.0 | N | 0.743 | 0.469 | 0.253726318573 | gnomAD-4.0.0 | 6.84567E-07 | None | None | None | None | N | None | 0 | 2.23764E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 17826 |
Fn3-17 |
63 | rs1158023438 |
0.855 | None | 1.0 | N | 0.76 | 0.567 | 0.797182237053 | gnomAD-4.0.0 | 1.36913E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79966E-06 | 0 | 0 |
| N/D | 17926 |
Fn3-18 |
65 | None | 0.0805 | None | None | N | 0.177 | 0.073 | 0.107399877778 | gnomAD-4.0.0 | 1.59431E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43476E-05 | 0 |
| R/C | 18235 |
Fn3-20 |
70 | rs758019427 |
0.377 | -0.19 | 1.0 | N | 0.659 | 0.351 | 0.568285537894 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.9E-06 | 0 |
| R/C | 18235 |
Fn3-20 |
70 | rs758019427 |
0.377 | -0.19 | 1.0 | N | 0.659 | 0.351 | 0.568285537894 | gnomAD-4.0.0 | 2.73845E-06 | None | None | None | None | N | None | 2.99383E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99941E-07 | 1.16015E-05 | 1.65799E-05 |
| R/G | 18235 |
Fn3-20 |
70 | rs758019427 |
0.4203 | 0.035 | 0.996 | N | 0.505 | 0.333 | 0.393471546983 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| R/G | 18235 |
Fn3-20 |
70 | rs758019427 |
0.4203 | 0.035 | 0.996 | N | 0.505 | 0.333 | 0.393471546983 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/G | 18235 |
Fn3-20 |
70 | rs758019427 |
0.4203 | 0.035 | 0.996 | N | 0.505 | 0.333 | 0.393471546983 | gnomAD-4.0.0 | 3.10069E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.24046E-06 | 0 | 0 |
| R/H | 18235 |
Fn3-20 |
70 | rs750125113 |
0.1969 | -0.509 | 0.67 | N | 0.417 | 0.269 | 0.253205268125 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| R/H | 18235 |
Fn3-20 |
70 | rs750125113 |
0.1969 | -0.509 | 0.67 | N | 0.417 | 0.269 | 0.253205268125 | gnomAD-4.0.0 | 8.89995E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.51355E-04 | None | 0 | 0 | 3.59978E-06 | 3.48044E-05 | 0 |
| N/K | 18338 |
Fn3-21 |
67 | None | 0.2301 | None | 0.801 | N | 0.346 | 0.111 | 0.162503812791 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/H | 18542 |
Fn3-22 |
64 | rs1391131193 |
0.489 | 0.574 | 0.994 | N | 0.51 | 0.394 | 0.346315397577 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/H | 18542 |
Fn3-22 |
64 | rs1391131193 |
0.489 | 0.574 | 0.994 | N | 0.51 | 0.394 | 0.346315397577 | gnomAD-4.0.0 | 1.59372E-06 | None | None | None | None | N | None | 0 | 2.2899E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 18542 |
Fn3-22 |
64 | rs1391131193 |
0.4366 | 0.189 | 0.998 | N | 0.599 | 0.392 | 0.585624173979 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| D/Y | 18542 |
Fn3-22 |
64 | rs1391131193 |
0.4366 | 0.189 | 0.998 | N | 0.599 | 0.392 | 0.585624173979 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/Y | 18542 |
Fn3-22 |
64 | rs1391131193 |
0.4366 | 0.189 | 0.998 | N | 0.599 | 0.392 | 0.585624173979 | gnomAD-4.0.0 | 5.13189E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.58405E-06 | 0 | 0 |
| K/E | 18848 |
Fn3-24 |
65 | rs2052641171 |
0.4179 | None | 0.961 | N | 0.461 | 0.204 | 0.272639205421 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 18848 |
Fn3-24 |
65 | rs2052641171 |
0.4179 | None | 0.961 | N | 0.461 | 0.204 | 0.272639205421 | gnomAD-4.0.0 | 6.57765E-06 | None | None | None | None | N | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 18848 |
Fn3-24 |
65 | rs879138127 |
0.0797 | None | 0.031 | N | 0.139 | 0.084 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 18848 |
Fn3-24 |
65 | rs879138127 |
0.0797 | None | 0.031 | N | 0.139 | 0.084 | None | gnomAD-4.0.0 | 6.57843E-06 | None | None | None | None | N | None | 2.41383E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 18952 |
Fn3-25 |
69 | rs766126662 |
0.1274 | -0.276 | 1.0 | N | 0.749 | 0.504 | 0.393775345888 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 0 | 2.32072E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/S | 18952 |
Fn3-25 |
69 | rs766126662 |
0.1274 | -0.276 | 1.0 | N | 0.749 | 0.504 | 0.393775345888 | gnomAD-4.0.0 | 4.79067E-06 | None | None | None | None | N | None | 0 | 1.56593E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 18952 |
Fn3-25 |
69 | rs762735652 |
0.781 | -0.001 | 1.0 | D | 0.749 | 0.53 | 0.586023110755 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| G/V | 18952 |
Fn3-25 |
69 | rs762735652 |
0.781 | -0.001 | 1.0 | D | 0.749 | 0.53 | 0.586023110755 | gnomAD-4.0.0 | 1.02657E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.34946E-05 | 0 | 0 |
| G/E | 19052 |
Fn3-26 |
65 | rs867041175 |
0.1947 | None | 0.01 | N | 0.312 | 0.219 | 0.326616659874 | gnomAD-4.0.0 | 2.40068E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62504E-06 | 0 | 0 |
| G/R | 19052 |
Fn3-26 |
65 | rs2052208575 |
0.312 | None | 0.83 | N | 0.689 | 0.358 | 0.637269506179 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 19052 |
Fn3-26 |
65 | rs2052208575 |
0.312 | None | 0.83 | N | 0.689 | 0.358 | 0.637269506179 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31252E-06 | 0 | 0 |
| G/A | 19247 |
Fn3-27 |
65 | None | 0.2497 | None | 1.0 | N | 0.686 | 0.454 | 0.411265580357 | gnomAD-4.0.0 | 6.91505E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.06024E-07 | 0 | 0 |
| G/D | 19247 |
Fn3-27 |
65 | None | 0.204 | None | 1.0 | N | 0.734 | 0.48 | 0.399304321381 | gnomAD-4.0.0 | 6.91505E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.67079E-05 |
| G/R | 19247 |
Fn3-27 |
65 | None | 0.6191 | None | 1.0 | D | 0.767 | 0.512 | 0.66259775642 | gnomAD-4.0.0 | 1.63002E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.8255E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 19247 |
Fn3-27 |
65 | rs1222912274 |
0.519 | 0.017 | 1.0 | D | 0.749 | 0.575 | 0.701705663459 | gnomAD-2.1.1 | 4.43E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.97E-06 | 0 |
| G/V | 19247 |
Fn3-27 |
65 | rs1222912274 |
0.519 | 0.017 | 1.0 | D | 0.749 | 0.575 | 0.701705663459 | gnomAD-4.0.0 | 6.91505E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.74216E-04 | 0 | 0 | 0 |
| G/D | 19348 |
Fn3-28 |
65 | rs530742564 |
0.1163 | -0.323 | 0.085 | N | 0.327 | 0.148 | 0.0986583533028 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/D | 19348 |
Fn3-28 |
65 | rs530742564 |
0.1163 | -0.323 | 0.085 | N | 0.327 | 0.148 | 0.0986583533028 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| G/D | 19348 |
Fn3-28 |
65 | rs530742564 |
0.1163 | -0.323 | 0.085 | N | 0.327 | 0.148 | 0.0986583533028 | gnomAD-4.0.0 | 6.57376E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47119E-05 | 0 | 0 |
| K/E | 19543 |
Fn3-29 |
65 | None | 0.5704 | None | 0.999 | N | 0.613 | 0.337 | 0.357313475932 | gnomAD-4.0.0 | 1.59232E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| D/G | 19643 |
Fn3-30 |
65 | rs2050641106 |
0.1914 | None | 0.989 | N | 0.704 | 0.418 | 0.200317383148 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/G | 19643 |
Fn3-30 |
65 | rs2050641106 |
0.1914 | None | 0.989 | N | 0.704 | 0.418 | 0.200317383148 | gnomAD-4.0.0 | 6.57696E-06 | None | None | None | None | N | None | 2.41383E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 19643 |
Fn3-30 |
65 | rs794729464 |
0.3978 | 0.449 | 0.999 | N | 0.689 | 0.414 | 0.358540694251 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/H | 19643 |
Fn3-30 |
65 | rs794729464 |
0.3978 | 0.449 | 0.999 | N | 0.689 | 0.414 | 0.358540694251 | gnomAD-4.0.0 | 3.18394E-06 | None | None | None | None | N | None | 0 | 4.5754E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 19746 |
Fn3-31 |
67 | None | 0.4961 | None | 1.0 | N | 0.669 | 0.44 | 0.623005408949 | gnomAD-4.0.0 | 6.84321E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99603E-07 | 0 | 0 |
| G/S | 19746 |
Fn3-31 |
67 | rs372802352 |
0.1158 | -0.327 | 0.999 | N | 0.494 | 0.322 | None | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | N | None | 4.54771E-04 | 8.49E-05 | None | 0 | 0 | None | 0 | None | 0 | 7.82E-06 | 0 |
| G/S | 19746 |
Fn3-31 |
67 | rs372802352 |
0.1158 | -0.327 | 0.999 | N | 0.494 | 0.322 | None | gnomAD-3.1.2 | 1.11847E-04 | None | None | None | None | N | None | 3.86417E-04 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 19746 |
Fn3-31 |
67 | rs372802352 |
0.1158 | -0.327 | 0.999 | N | 0.494 | 0.322 | None | gnomAD-4.0.0 | 3.22322E-05 | None | None | None | None | N | None | 4.00759E-04 | 6.67223E-05 | None | 0 | 0 | None | 0 | 0 | 1.35642E-05 | 0 | 3.20287E-05 |
| H/Q | 19940 |
Fn3-32 |
64 | None | 0.1944 | None | 0.995 | N | 0.461 | 0.185 | 0.262662153117 | gnomAD-4.0.0 | 5.47618E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.29764E-06 | 0 | 1.65777E-05 |
| H/Y | 19940 |
Fn3-32 |
64 | rs192279089 |
0.0639 | 0.99 | 0.026 | N | 0.181 | 0.137 | 0.1749357433 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| H/Y | 19940 |
Fn3-32 |
64 | rs192279089 |
0.0639 | 0.99 | 0.026 | N | 0.181 | 0.137 | 0.1749357433 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/Y | 19940 |
Fn3-32 |
64 | rs192279089 |
0.0639 | 0.99 | 0.026 | N | 0.181 | 0.137 | 0.1749357433 | gnomAD-4.0.0 | 8.06018E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.10216E-05 | 0 | 0 |
| G/R | 20039 |
Fn3-33 |
63 | rs2050244000 |
0.4561 | None | 1.0 | N | 0.803 | 0.509 | 0.724626463931 | gnomAD-4.0.0 | 1.59195E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43316E-05 | 0 |
| G/V | 20039 |
Fn3-33 |
63 | None | 0.5795 | None | 1.0 | N | 0.785 | 0.514 | 0.753156384521 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| H/L | 20235 |
Fn3-34 |
65 | None | 0.1383 | None | 0.425 | N | 0.401 | 0.201 | 0.485493271093 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| H/Q | 20235 |
Fn3-34 |
65 | rs745785822 |
0.1977 | 0.279 | 0.642 | N | 0.299 | 0.069 | 0.162503812791 | gnomAD-2.1.1 | 5.65E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.57576E-04 | None | 0 | 0 | 0 |
| H/Q | 20235 |
Fn3-34 |
65 | rs745785822 |
0.1977 | 0.279 | 0.642 | N | 0.299 | 0.069 | 0.162503812791 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| H/Q | 20235 |
Fn3-34 |
65 | rs745785822 |
0.1977 | 0.279 | 0.642 | N | 0.299 | 0.069 | 0.162503812791 | gnomAD-4.0.0 | 2.47931E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.17243E-04 | 3.20297E-05 |
| H/R | 20235 |
Fn3-34 |
65 | rs2050096769 |
0.0885 | None | 0.001 | N | 0.116 | 0.15 | 0.136095386433 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 20235 |
Fn3-34 |
65 | rs2050096769 |
0.0885 | None | 0.001 | N | 0.116 | 0.15 | 0.136095386433 | gnomAD-4.0.0 | 2.03005E-06 | None | None | None | None | N | None | 1.74758E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20497E-06 | 0 | 0 |
| G/E | 20334 |
Fn3-35 |
64 | rs779468027 |
0.6649 | -0.429 | 1.0 | N | 0.751 | 0.549 | 0.609889067838 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| G/E | 20334 |
Fn3-35 |
64 | rs779468027 |
0.6649 | -0.429 | 1.0 | N | 0.751 | 0.549 | 0.609889067838 | gnomAD-4.0.0 | 1.59411E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86288E-06 | 0 | 0 |
| G/R | 20334 |
Fn3-35 |
64 | rs2050027400 |
0.7658 | None | 1.0 | N | 0.769 | 0.557 | 0.728201419959 | gnomAD-4.0.0 | 2.73905E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.6999E-06 | 1.16201E-05 | 0 |
| N/D | 20631 |
Fn3-37 |
63 | None | 0.2231 | None | 0.425 | N | 0.421 | 0.18 | 0.115124310173 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/K | 20631 |
Fn3-37 |
63 | rs940775890 |
0.4182 | 0.083 | 0.01 | N | 0.155 | 0.173 | 0.0986583533028 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| N/K | 20631 |
Fn3-37 |
63 | rs940775890 |
0.4182 | 0.083 | 0.01 | N | 0.155 | 0.173 | 0.0986583533028 | gnomAD-4.0.0 | 3.42163E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.52321E-05 | None | 0 | 0 | 3.59837E-06 | 0 | 0 |
| N/S | 20631 |
Fn3-37 |
63 | rs2049834334 |
0.087 | None | 0.023 | N | 0.19 | 0.153 | 0.104622674875 | gnomAD-4.0.0 | 1.59188E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02462E-05 |
| R/S | 20732 |
Fn3-38 |
65 | None | 0.3654 | None | 0.012 | N | 0.279 | 0.062 | 0.158396225186 | gnomAD-4.0.0 | 6.36819E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.14362E-05 | 0 | 0 |
| R/C | 20927 |
Fn3-39 |
64 | rs547604540 |
0.3892 | 0.002 | 1.0 | N | 0.651 | 0.451 | 0.661991603742 | gnomAD-2.1.1 | 1.44E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 2.36E-05 | 0 |
| R/C | 20927 |
Fn3-39 |
64 | rs547604540 |
0.3892 | 0.002 | 1.0 | N | 0.651 | 0.451 | 0.661991603742 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/C | 20927 |
Fn3-39 |
64 | rs547604540 |
0.3892 | 0.002 | 1.0 | N | 0.651 | 0.451 | 0.661991603742 | gnomAD-4.0.0 | 1.79839E-05 | None | None | None | None | N | None | 1.33586E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.3741E-05 | 0 | 0 |
| R/H | 20927 |
Fn3-39 |
64 | rs397517652 |
0.1726 | -0.765 | 0.132 | N | 0.165 | 0.178 | 0.166414681773 | gnomAD-2.1.1 | 1.08E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| R/H | 20927 |
Fn3-39 |
64 | rs397517652 |
0.1726 | -0.765 | 0.132 | N | 0.165 | 0.178 | 0.166414681773 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 1.20802E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/H | 20927 |
Fn3-39 |
64 | rs397517652 |
0.1726 | -0.765 | 0.132 | N | 0.165 | 0.178 | 0.166414681773 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/H | 20927 |
Fn3-39 |
64 | rs397517652 |
0.1726 | -0.765 | 0.132 | N | 0.165 | 0.178 | 0.166414681773 | gnomAD-4.0.0 | 1.61224E-05 | None | None | None | None | N | None | 8.00406E-05 | 1.66995E-05 | None | 0 | 2.24266E-05 | None | 0 | 0 | 1.52622E-05 | 0 | 0 |
| S/I | 21134 |
Fn3-41 |
71 | None | 0.2659 | None | 0.996 | N | 0.423 | 0.32 | 0.430579932962 | gnomAD-4.0.0 | 1.59341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43361E-05 | 0 |
| S/N | 21134 |
Fn3-41 |
71 | None | 0.1215 | None | 0.134 | N | 0.149 | 0.121 | 0.0611884634855 | gnomAD-4.0.0 | 1.59341E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86139E-06 | 0 | 0 |
| N/S | 21329 |
Fn3-42 |
64 | rs754342548 |
0.0688 | 0.211 | 0.944 | N | 0.521 | 0.205 | 0.224531998449 | gnomAD-2.1.1 | 2.82E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 4.45E-05 | 0 |
| N/S | 21329 |
Fn3-42 |
64 | rs754342548 |
0.0688 | 0.211 | 0.944 | N | 0.521 | 0.205 | 0.224531998449 | gnomAD-3.1.2 | 4.61E-05 | None | None | None | None | N | None | 2.41E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 7.36E-05 | 0 | 0 |
| N/S | 21329 |
Fn3-42 |
64 | rs754342548 |
0.0688 | 0.211 | 0.944 | N | 0.521 | 0.205 | 0.224531998449 | gnomAD-4.0.0 | 1.73578E-05 | None | None | None | None | N | None | 2.67222E-05 | 1.66834E-05 | None | 0 | 0 | None | 3.12383E-05 | 0 | 1.44132E-05 | 1.09803E-05 | 8.01E-05 |
| N/T | 21329 |
Fn3-42 |
64 | rs754342548 |
0.1263 | None | 0.892 | N | 0.596 | 0.311 | 0.298403945805 | gnomAD-4.0.0 | 6.84404E-07 | None | None | None | None | N | None | 2.99097E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 21430 |
Fn3-43 |
65 | rs1186264863 |
0.3472 | None | 1.0 | N | 0.695 | 0.447 | 0.400468435593 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 21430 |
Fn3-43 |
65 | rs1186264863 |
0.3472 | None | 1.0 | N | 0.695 | 0.447 | 0.400468435593 | gnomAD-4.0.0 | 6.57601E-06 | None | None | None | None | N | None | 2.41348E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 21430 |
Fn3-43 |
65 | None | 0.5062 | None | 1.0 | N | 0.757 | 0.427 | 0.379707525713 | gnomAD-4.0.0 | 3.18524E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72207E-06 | 0 | 0 |
| G/S | 21430 |
Fn3-43 |
65 | rs2049038476 |
0.2202 | None | 1.0 | N | 0.767 | 0.444 | 0.370240404367 | gnomAD-4.0.0 | 1.59258E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43303E-05 | 0 |
| G/D | 21723 |
Fn3-45 |
65 | rs371802736 |
0.4985 | -0.283 | 0.997 | N | 0.765 | 0.405 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| G/D | 21723 |
Fn3-45 |
65 | rs371802736 |
0.4985 | -0.283 | 0.997 | N | 0.765 | 0.405 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 9.56938E-04 |
| G/D | 21723 |
Fn3-45 |
65 | rs371802736 |
0.4985 | -0.283 | 0.997 | N | 0.765 | 0.405 | None | gnomAD-4.0.0 | 6.19899E-06 | None | None | None | None | N | None | 0 | 1.66744E-05 | None | 0 | 0 | None | 0 | 3.29056E-04 | 4.23913E-06 | 0 | 3.20338E-05 |
| G/D | 21823 |
Fn3-46 |
67 | None | 0.1535 | None | 0.235 | N | 0.312 | 0.215 | 0.168933306366 | gnomAD-4.0.0 | 1.59466E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88523E-05 | 0 | 0 | 0 | 0 |
| K/I | 22019 |
Fn3-47 |
64 | rs1164328228 |
0.9373 | None | 0.97 | N | 0.61 | 0.366 | 0.48748946032 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/S | 22119 |
Fn3-48 |
65 | rs901951990 |
0.1303 | -0.28 | 0.698 | N | 0.381 | 0.208 | 0.214338557667 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| N/Y | 22417 |
Fn3-50 |
64 | rs769066160 |
0.1974 | -0.43 | 0.998 | N | 0.674 | 0.411 | 0.507687591559 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| N/Y | 22417 |
Fn3-50 |
64 | rs769066160 |
0.1974 | -0.43 | 0.998 | N | 0.674 | 0.411 | 0.507687591559 | gnomAD-4.0.0 | 1.59219E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| D/E | 22512 |
Fn3-51 |
62 | rs760531418 |
0.1526 | None | 0.039 | N | 0.225 | 0.069 | 0.130388298395 | gnomAD-4.0.0 | 1.08029E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18125E-05 | 0 | 0 |
| D/G | 22512 |
Fn3-51 |
62 | None | 0.1058 | None | 0.928 | N | 0.719 | 0.459 | 0.297031009988 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/Y | 22512 |
Fn3-51 |
62 | rs786205540 |
0.1809 | None | 0.999 | N | 0.749 | 0.371 | 0.638151879823 | gnomAD-4.0.0 | 3.18433E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.82859E-04 | 0 | 0 | 0 |
| G/E | 22807 |
Fn3-53 |
65 | None | 0.4609 | None | 1.0 | N | 0.718 | 0.564 | 0.453307948783 | gnomAD-4.0.0 | 1.59237E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43316E-05 | 0 |
| G/R | 22807 |
Fn3-53 |
65 | rs753494082 |
0.5563 | 0.011 | 1.0 | N | 0.759 | 0.495 | 0.578910049572 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| G/R | 22807 |
Fn3-53 |
65 | rs753494082 |
0.5563 | 0.011 | 1.0 | N | 0.759 | 0.495 | 0.578910049572 | gnomAD-4.0.0 | 6.84419E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99672E-07 | 0 | 0 |
| D/E | 22905 |
Fn3-54 |
65 | None | 0.2331 | None | 1.0 | N | 0.453 | 0.298 | 0.286465849087 | gnomAD-4.0.0 | 2.05317E-06 | None | None | None | None | N | None | 2.98882E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79923E-06 | 0 | 0 |
| K/R | 23103 |
Fn3-55 |
64 | None | 0.099 | None | 0.99 | N | 0.483 | 0.285 | 0.21279746466 | gnomAD-4.0.0 | 1.59186E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85966E-06 | 0 | 0 |
| G/E | 23203 |
Fn3-56 |
65 | rs575899662 |
0.6309 | -0.193 | 0.995 | N | 0.751 | 0.419 | 0.484691182572 | gnomAD-2.1.1 | 1.08585E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 8.82353E-04 | None | 0 | 0 | 0 |
| G/E | 23203 |
Fn3-56 |
65 | rs575899662 |
0.6309 | -0.193 | 0.995 | N | 0.751 | 0.419 | 0.484691182572 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 8.30565E-04 | 0 |
| G/E | 23203 |
Fn3-56 |
65 | rs575899662 |
0.6309 | -0.193 | 0.995 | N | 0.751 | 0.419 | 0.484691182572 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| G/E | 23203 |
Fn3-56 |
65 | rs575899662 |
0.6309 | -0.193 | 0.995 | N | 0.751 | 0.419 | 0.484691182572 | gnomAD-4.0.0 | 5.6397E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 9.3345E-04 | 9.60584E-05 |
| D/N | 23305 |
Fn3-57 |
66 | None | 0.069 | None | None | N | 0.163 | 0.176 | 0.219573609325 | gnomAD-4.0.0 | 2.05367E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69921E-06 | 0 | 0 |
| G/D | 23498 |
Fn3-58 |
64 | rs770261949 |
0.1342 | 0.126 | None | N | 0.233 | 0.076 | 0.159798565429 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| G/S | 23498 |
Fn3-58 |
64 | rs370771532 |
0.0884 | -0.149 | 0.442 | N | 0.399 | 0.154 | None | gnomAD-2.1.1 | 2.32246E-04 | None | None | None | None | N | None | 4.54658E-04 | 0 | None | 4.06425E-03 | 0 | None | 3.27E-05 | None | 0 | 7.82E-05 | 1.40568E-04 |
| G/S | 23498 |
Fn3-58 |
64 | rs370771532 |
0.0884 | -0.149 | 0.442 | N | 0.399 | 0.154 | None | gnomAD-3.1.2 | 2.43328E-04 | None | None | None | None | N | None | 3.86138E-04 | 0 | 0 | 3.4642E-03 | 0 | None | 0 | 0 | 1.32372E-04 | 0 | 0 |
| G/S | 23498 |
Fn3-58 |
64 | rs370771532 |
0.0884 | -0.149 | 0.442 | N | 0.399 | 0.154 | None | gnomAD-4.0.0 | 1.80983E-04 | None | None | None | None | N | None | 2.93733E-04 | 0 | None | 3.27858E-03 | 0 | None | 0 | 0 | 1.30548E-04 | 2.19631E-05 | 2.72253E-04 |
| N/D | 23594 |
Fn3-59 |
63 | None | 0.1357 | None | None | N | 0.081 | 0.106 | 0.195762928549 | gnomAD-4.0.0 | 6.84314E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99546E-07 | 0 | 0 |
| N/Y | 23594 |
Fn3-59 |
63 | None | 0.2159 | None | 0.602 | N | 0.405 | 0.344 | 0.424670345773 | gnomAD-4.0.0 | 6.84314E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15942E-05 | 0 |
| R/C | 23790 |
Fn3-60 |
65 | rs775743818 |
0.2371 | -0.187 | 1.0 | N | 0.639 | 0.413 | 0.6544015285 | gnomAD-2.1.1 | 3.23E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.03252E-04 | None | 0 | None | 4.02E-05 | 4.72E-05 | 0 |
| R/C | 23790 |
Fn3-60 |
65 | rs775743818 |
0.2371 | -0.187 | 1.0 | N | 0.639 | 0.413 | 0.6544015285 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/C | 23790 |
Fn3-60 |
65 | rs775743818 |
0.2371 | -0.187 | 1.0 | N | 0.639 | 0.413 | 0.6544015285 | gnomAD-4.0.0 | 3.41152E-05 | None | None | None | None | I | None | 1.33576E-05 | 0 | None | 0 | 4.47067E-05 | None | 0 | 0 | 4.3257E-05 | 0 | 1.60313E-05 |
| R/G | 23790 |
Fn3-60 |
65 | None | 0.3767 | None | 0.922 | N | 0.486 | 0.333 | 0.418718287753 | gnomAD-4.0.0 | 6.8487E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00093E-07 | 0 | 0 |
| R/H | 23790 |
Fn3-60 |
65 | rs55677134 |
0.1136 | -0.511 | 0.159 | N | 0.363 | 0.083 | None | gnomAD-2.1.1 | 1.21492E-03 | None | None | None | None | I | None | 0 | 1.13733E-04 | None | 0 | 1.65119E-02 | None | 1.97811E-04 | None | 0 | 3.15E-05 | 5.67054E-04 |
| R/H | 23790 |
Fn3-60 |
65 | rs55677134 |
0.1136 | -0.511 | 0.159 | N | 0.363 | 0.083 | None | gnomAD-3.1.2 | 7.03827E-04 | None | None | None | None | I | None | 0 | 6.56E-05 | 0 | 0 | 2.00078E-02 | None | 0 | 0 | 2.94E-05 | 2.07469E-04 | 0 |
| R/H | 23790 |
Fn3-60 |
65 | rs55677134 |
0.1136 | -0.511 | 0.159 | N | 0.363 | 0.083 | None | 1000 genomes | 5.79073E-03 | None | None | None | None | I | None | 0 | 0 | None | None | 2.88E-02 | 0 | None | None | None | 0 | None |
| R/H | 23790 |
Fn3-60 |
65 | rs55677134 |
0.1136 | -0.511 | 0.159 | N | 0.363 | 0.083 | None | gnomAD-4.0.0 | 7.80964E-04 | None | None | None | None | I | None | 0 | 8.35031E-05 | None | 0 | 2.63581E-02 | None | 0 | 0 | 2.12066E-05 | 2.09187E-04 | 4.96779E-04 |
| R/P | 23790 |
Fn3-60 |
65 | None | 0.8664 | None | 0.988 | N | 0.563 | 0.298 | 0.288352970974 | gnomAD-4.0.0 | 6.84947E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65859E-05 |
| G/D | 23988 |
Fn3-62 |
65 | rs1320505610 |
0.6396 | None | 1.0 | N | 0.743 | 0.525 | 0.177238962908 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 23988 |
Fn3-62 |
65 | rs1320505610 |
0.6396 | None | 1.0 | N | 0.743 | 0.525 | 0.177238962908 | gnomAD-4.0.0 | 6.57514E-06 | None | None | None | None | N | None | 2.41383E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 24186 |
Fn3-63 |
65 | rs768699380 |
0.7865 | 0.197 | 0.892 | N | 0.549 | 0.232 | 0.311691414656 | gnomAD-2.1.1 | 2.51E-05 | None | None | None | None | N | None | 2.16863E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/E | 24186 |
Fn3-63 |
65 | rs768699380 |
0.7865 | 0.197 | 0.892 | N | 0.549 | 0.232 | 0.311691414656 | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 2.65316E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 24186 |
Fn3-63 |
65 | rs768699380 |
0.7865 | 0.197 | 0.892 | N | 0.549 | 0.232 | 0.311691414656 | gnomAD-4.0.0 | 1.13497E-05 | None | None | None | None | N | None | 2.38409E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 24286 |
Fn3-64 |
65 | rs1198682781 |
0.6802 | 0.009 | 1.0 | N | 0.763 | 0.488 | 0.700283151579 | gnomAD-2.1.1 | 4.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.15E-06 | 0 |
| G/R | 24286 |
Fn3-64 |
65 | rs1198682781 |
0.6802 | 0.009 | 1.0 | N | 0.763 | 0.488 | 0.700283151579 | gnomAD-4.0.0 | 1.38034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80919E-06 | 0 | 0 |
| G/V | 24286 |
Fn3-64 |
65 | None | 0.5043 | None | 1.0 | D | 0.758 | 0.54 | 0.857685105731 | gnomAD-4.0.0 | 1.62324E-06 | None | None | None | None | N | None | 0 | 2.37575E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 24388 |
Fn3-65 |
66 | rs768369089 |
0.0664 | -0.143 | None | N | 0.095 | 0.082 | 0.0611884634855 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/S | 24388 |
Fn3-65 |
66 | rs768369089 |
0.0664 | -0.143 | None | N | 0.095 | 0.082 | 0.0611884634855 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 24388 |
Fn3-65 |
66 | rs768369089 |
0.0664 | -0.143 | None | N | 0.095 | 0.082 | 0.0611884634855 | gnomAD-4.0.0 | 2.56421E-06 | None | None | None | None | N | None | 1.69228E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.34055E-05 | 0 |
| Q/H | 24582 |
Fn3-66 |
64 | None | 0.1123 | None | 0.448 | N | 0.357 | 0.066 | 0.264081493735 | gnomAD-4.0.0 | 6.84538E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65755E-05 |
| Q/P | 24582 |
Fn3-66 |
64 | rs375186364 |
0.1284 | -0.306 | None | N | 0.151 | 0.24 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Q/P | 24582 |
Fn3-66 |
64 | rs375186364 |
0.1284 | -0.306 | None | N | 0.151 | 0.24 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| Q/P | 24582 |
Fn3-66 |
64 | rs375186364 |
0.1284 | -0.306 | None | N | 0.151 | 0.24 | None | gnomAD-4.0.0 | 1.30192E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.78074E-05 | 0 | 0 |
| G/E | 24678 |
Fn3-67 |
63 | rs1708418492 |
0.5709 | None | 0.998 | N | 0.773 | 0.48 | 0.581056753333 | gnomAD-4.0.0 | 3.18518E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56948E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 24678 |
Fn3-67 |
63 | rs756307970 |
0.6413 | -0.109 | 1.0 | N | 0.77 | 0.466 | 0.613267566169 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 0 | 0 |
| G/R | 24678 |
Fn3-67 |
63 | rs756307970 |
0.6413 | -0.109 | 1.0 | N | 0.77 | 0.466 | 0.613267566169 | gnomAD-4.0.0 | 3.18522E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86681E-05 | 0 |
| R/K | 24872 |
Fn3-68 |
65 | rs923165795 |
0.1665 | 0.305 | 0.026 | N | 0.23 | 0.129 | 0.188950314367 | gnomAD-2.1.1 | 7.17E-06 | None | None | None | None | I | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/K | 24872 |
Fn3-68 |
65 | rs923165795 |
0.1665 | 0.305 | 0.026 | N | 0.23 | 0.129 | 0.188950314367 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.77555E-04 |
| R/K | 24872 |
Fn3-68 |
65 | rs923165795 |
0.1665 | 0.305 | 0.026 | N | 0.23 | 0.129 | 0.188950314367 | gnomAD-4.0.0 | 5.1278E-06 | None | None | None | None | I | None | 5.07666E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84592E-05 |
| G/S | 24972 |
Fn3-69 |
65 | None | 0.111 | None | 0.997 | N | 0.745 | 0.343 | 0.241664281697 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 25268 |
Fn3-71 |
65 | rs1324895308 |
0.8077 | 0.318 | 0.967 | N | 0.648 | 0.252 | 0.180583059064 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/N | 25268 |
Fn3-71 |
65 | rs1324895308 |
0.8077 | 0.318 | 0.967 | N | 0.648 | 0.252 | 0.180583059064 | gnomAD-4.0.0 | 1.59236E-06 | None | None | None | None | N | None | 0 | 2.28822E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 25368 |
Fn3-72 |
65 | rs551988703 |
0.8363 | -0.102 | 1.0 | N | 0.775 | 0.588 | 0.745312688576 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94024E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 25368 |
Fn3-72 |
65 | rs551988703 |
0.8363 | -0.102 | 1.0 | N | 0.775 | 0.588 | 0.745312688576 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| G/R | 25368 |
Fn3-72 |
65 | rs551988703 |
0.8363 | -0.102 | 1.0 | N | 0.775 | 0.588 | 0.745312688576 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| G/V | 25368 |
Fn3-72 |
65 | rs753304499 |
0.7702 | 0.013 | 1.0 | D | 0.762 | 0.622 | 0.883579667158 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| G/V | 25368 |
Fn3-72 |
65 | rs753304499 |
0.7702 | 0.013 | 1.0 | D | 0.762 | 0.622 | 0.883579667158 | gnomAD-4.0.0 | 1.59238E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85987E-06 | 0 | 0 |
| Q/R | 25664 |
Fn3-74 |
64 | rs750836294 |
0.1002 | 0.519 | 0.004 | N | 0.345 | 0.127 | 0.0806252709748 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.65E-05 | 2.67E-05 | 0 |
| Q/R | 25664 |
Fn3-74 |
64 | rs750836294 |
0.1002 | 0.519 | 0.004 | N | 0.345 | 0.127 | 0.0806252709748 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| Q/R | 25664 |
Fn3-74 |
64 | rs750836294 |
0.1002 | 0.519 | 0.004 | N | 0.345 | 0.127 | 0.0806252709748 | gnomAD-4.0.0 | 4.33896E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.12402E-05 | 0 | 4.23895E-06 | 0 | 0 |
| N/K | 25760 |
Fn3-75 |
63 | None | 0.3734 | None | 0.892 | N | 0.496 | 0.232 | 0.126345400529 | gnomAD-4.0.0 | 6.84495E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99604E-07 | 0 | 0 |
| N/S | 25760 |
Fn3-75 |
63 | rs3813246 |
0.0789 | 0.257 | 0.243 | N | 0.283 | 0.116 | None | gnomAD-2.1.1 | 2.57166E-02 | None | None | None | None | N | None | 4.83791E-03 | 3.34768E-02 | None | 1.4612E-02 | 6.13756E-02 | None | 6.04891E-03 | None | 4.81879E-02 | 2.33044E-02 | 2.64565E-02 |
| N/S | 25760 |
Fn3-75 |
63 | rs3813246 |
0.0789 | 0.257 | 0.243 | N | 0.283 | 0.116 | None | gnomAD-3.1.2 | 2.01989E-02 | None | None | None | None | N | None | 4.44166E-03 | 2.18619E-02 | 3.07018E-02 | 1.90202E-02 | 6.1339E-02 | None | 4.42036E-02 | 6.32911E-03 | 2.34033E-02 | 8.28157E-03 | 1.95985E-02 |
| N/S | 25760 |
Fn3-75 |
63 | rs3813246 |
0.0789 | 0.257 | 0.243 | N | 0.283 | 0.116 | None | 1000 genomes | 2.23642E-02 | None | None | None | None | N | None | 8E-04 | 2.45E-02 | None | None | 6.05E-02 | 2.68E-02 | None | None | None | 6.1E-03 | None |
| N/S | 25760 |
Fn3-75 |
63 | rs3813246 |
0.0789 | 0.257 | 0.243 | N | 0.283 | 0.116 | None | gnomAD-4.0.0 | 2.28761E-02 | None | None | None | None | N | None | 4.25367E-03 | 2.93706E-02 | None | 1.48719E-02 | 6.31891E-02 | None | 4.76071E-02 | 9.74884E-03 | 2.24335E-02 | 6.7762E-03 | 2.16459E-02 |
| K/Q | 25954 |
Fn3-76 |
65 | rs776215265 |
0.2896 | 0.212 | 0.994 | N | 0.508 | 0.293 | 0.233785782151 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| K/Q | 25954 |
Fn3-76 |
65 | rs776215265 |
0.2896 | 0.212 | 0.994 | N | 0.508 | 0.293 | 0.233785782151 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| N/T | 26054 |
Fn3-77 |
65 | None | 0.1052 | None | 0.98 | N | 0.439 | 0.258 | 0.337621943819 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/C | 26152 |
Fn3-78 |
65 | None | 0.5429 | None | 1.0 | D | 0.728 | 0.502 | 0.645716986391 | gnomAD-4.0.0 | 6.84836E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0014E-07 | 0 | 0 |
| G/D | 26152 |
Fn3-78 |
65 | None | 0.7524 | None | 0.997 | N | 0.769 | 0.41 | 0.176091768786 | gnomAD-4.0.0 | 1.59453E-06 | None | None | None | None | N | None | 0 | 2.28969E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 26152 |
Fn3-78 |
65 | rs781374181 |
0.2009 | -0.285 | 0.778 | N | 0.523 | 0.373 | 0.143124449307 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 0 |
| G/S | 26152 |
Fn3-78 |
65 | rs781374181 |
0.2009 | -0.285 | 0.778 | N | 0.523 | 0.373 | 0.143124449307 | gnomAD-4.0.0 | 2.05451E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.70042E-06 | 0 | 0 |
| K/R | 26350 |
Fn3-79 |
65 | rs1278375861 |
0.0987 | 0.239 | 0.142 | N | 0.271 | 0.182 | 0.297375071883 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| K/R | 26350 |
Fn3-79 |
65 | rs1278375861 |
0.0987 | 0.239 | 0.142 | N | 0.271 | 0.182 | 0.297375071883 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| K/R | 26350 |
Fn3-79 |
65 | rs1278375861 |
0.0987 | 0.239 | 0.142 | N | 0.271 | 0.182 | 0.297375071883 | gnomAD-4.0.0 | 3.09891E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.45911E-05 | None | 0 | 0 | 2.54318E-06 | 0 | 0 |
| G/R | 26450 |
Fn3-80 |
65 | rs752326213 |
0.9154 | -0.117 | 0.997 | N | 0.763 | 0.527 | 0.700708160949 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/R | 26450 |
Fn3-80 |
65 | rs752326213 |
0.9154 | -0.117 | 0.997 | N | 0.763 | 0.527 | 0.700708160949 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 26450 |
Fn3-80 |
65 | rs752326213 |
0.9154 | -0.117 | 0.997 | N | 0.763 | 0.527 | 0.700708160949 | gnomAD-4.0.0 | 5.12723E-06 | None | None | None | None | N | None | 1.69165E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.18095E-06 | 0 | 0 |
| K/N | 26552 |
Fn3-81 |
66 | rs1305128121 |
0.1531 | 0.364 | 0.967 | N | 0.667 | 0.199 | 0.110078149338 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| K/N | 26552 |
Fn3-81 |
66 | rs1305128121 |
0.1531 | 0.364 | 0.967 | N | 0.667 | 0.199 | 0.110078149338 | gnomAD-4.0.0 | 7.95932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.42938E-05 | 0 | 0 |
| N/H | 26746 |
Fn3-82 |
64 | None | 0.128 | None | 0.015 | N | 0.259 | 0.151 | 0.168933306366 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 7.32654E-05 |
| N/K | 26746 |
Fn3-82 |
64 | rs1299776307 |
0.3119 | 0.473 | 0.684 | N | 0.325 | 0.134 | 0.148003135375 | gnomAD-4.0.0 | 1.59162E-06 | None | None | None | None | N | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 26842 |
Fn3-83 |
63 | rs1333464688 |
0.2395 | None | 0.408 | N | 0.73 | 0.312 | 0.399304321381 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 26842 |
Fn3-83 |
63 | rs1333464688 |
0.2395 | None | 0.408 | N | 0.73 | 0.312 | 0.399304321381 | gnomAD-4.0.0 | 3.71864E-06 | None | None | None | None | N | None | 6.67699E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47712E-07 | 0 | 0 |
| K/E | 27036 |
Fn3-84 |
65 | rs545554093 |
0.5548 | 0.111 | 0.822 | N | 0.484 | 0.256 | 0.269558022972 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| K/E | 27036 |
Fn3-84 |
65 | rs545554093 |
0.5548 | 0.111 | 0.822 | N | 0.484 | 0.256 | 0.269558022972 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 27036 |
Fn3-84 |
65 | rs545554093 |
0.5548 | 0.111 | 0.822 | N | 0.484 | 0.256 | 0.269558022972 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| K/E | 27036 |
Fn3-84 |
65 | rs545554093 |
0.5548 | 0.111 | 0.822 | N | 0.484 | 0.256 | 0.269558022972 | gnomAD-4.0.0 | 2.0297E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.2779E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 27136 |
Fn3-85 |
65 | rs879200560 |
0.1359 | None | 0.201 | N | 0.368 | 0.229 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| G/A | 27136 |
Fn3-85 |
65 | rs879200560 |
0.1359 | None | 0.201 | N | 0.368 | 0.229 | None | gnomAD-4.0.0 | 2.47974E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39107E-05 | 0 | 0 |
| G/E | 27234 |
Fn3-86 |
65 | rs372189553 |
0.7258 | -0.427 | 1.0 | N | 0.744 | 0.409 | None | gnomAD-2.1.1 | 3.96E-05 | None | None | None | None | N | None | 4.15E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.91E-05 | 0 |
| G/E | 27234 |
Fn3-86 |
65 | rs372189553 |
0.7258 | -0.427 | 1.0 | N | 0.744 | 0.409 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| G/E | 27234 |
Fn3-86 |
65 | rs372189553 |
0.7258 | -0.427 | 1.0 | N | 0.744 | 0.409 | None | gnomAD-4.0.0 | 3.96824E-05 | None | None | None | None | N | None | 4.00555E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.74819E-05 | 0 | 8.01128E-05 |
| G/S | 27533 |
Fn3-88 |
65 | rs1704471479 |
0.1533 | None | 1.0 | N | 0.749 | 0.463 | 0.342631996419 | gnomAD-4.0.0 | 4.1053E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39691E-06 | 0 | 0 |
| K/E | 27635 |
Fn3-89 |
66 | None | 0.1116 | None | None | N | 0.267 | 0.075 | 0.19670166235 | gnomAD-4.0.0 | 3.18283E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71749E-06 | 0 | 0 |
| N/K | 27829 |
Fn3-90 |
64 | rs374322635 |
0.2323 | 0.467 | 0.27 | N | 0.276 | 0.079 | 0.119812018005 | gnomAD-2.1.1 | 8.48E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.84E-05 | 0 |
| N/K | 27829 |
Fn3-90 |
64 | rs374322635 |
0.2323 | 0.467 | 0.27 | N | 0.276 | 0.079 | 0.119812018005 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/K | 27829 |
Fn3-90 |
64 | rs374322635 |
0.2323 | 0.467 | 0.27 | N | 0.276 | 0.079 | 0.119812018005 | gnomAD-4.0.0 | 1.38009E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80568E-06 | 0 | 0 |
| G/A | 27925 |
Fn3-91 |
63 | None | 0.1957 | None | 0.937 | N | 0.639 | 0.417 | 0.344710718752 | gnomAD-4.0.0 | 1.59986E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44965E-05 | 0 |
| R/C | 28118 |
Fn3-92 |
64 | rs56057221 |
0.1977 | -0.279 | 1.0 | N | 0.65 | 0.371 | None | gnomAD-2.1.1 | 6.02293E-03 | None | None | None | None | I | None | 6.4408E-02 | 2.40766E-03 | None | 0 | 0 | None | 3.92336E-04 | None | 4E-05 | 1.33243E-04 | 1.5493E-03 |
| R/C | 28118 |
Fn3-92 |
64 | rs56057221 |
0.1977 | -0.279 | 1.0 | N | 0.65 | 0.371 | None | gnomAD-3.1.2 | 1.80138E-02 | None | None | None | None | I | None | 6.32456E-02 | 4.97969E-03 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 2.49919E-04 | 6.21633E-04 | 1.14723E-02 |
| R/C | 28118 |
Fn3-92 |
64 | rs56057221 |
0.1977 | -0.279 | 1.0 | N | 0.65 | 0.371 | None | 1000 genomes | 1.61741E-02 | None | None | None | None | I | None | 5.67E-02 | 8.6E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/C | 28118 |
Fn3-92 |
64 | rs56057221 |
0.1977 | -0.279 | 1.0 | N | 0.65 | 0.371 | None | gnomAD-4.0.0 | 3.41543E-03 | None | None | None | None | I | None | 6.51652E-02 | 3.36712E-03 | None | 0 | 4.46867E-05 | None | 1.56274E-05 | 1.81638E-03 | 7.62893E-05 | 3.07469E-04 | 4.64163E-03 |
| R/G | 28118 |
Fn3-92 |
64 | None | 0.2262 | None | 0.998 | N | 0.544 | 0.3 | 0.365509141856 | gnomAD-4.0.0 | 3.42152E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49759E-06 | 0 | 0 |
| R/H | 28118 |
Fn3-92 |
64 | rs72648220 |
0.0963 | -0.514 | 1.0 | N | 0.585 | 0.299 | 0.273938319068 | gnomAD-2.1.1 | 3.63E-05 | None | None | None | None | I | None | 0 | 8.71E-05 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 4.46E-05 | 0 |
| R/H | 28118 |
Fn3-92 |
64 | rs72648220 |
0.0963 | -0.514 | 1.0 | N | 0.585 | 0.299 | 0.273938319068 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | I | None | 7.24E-05 | 1.3101E-04 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| R/H | 28118 |
Fn3-92 |
64 | rs72648220 |
0.0963 | -0.514 | 1.0 | N | 0.585 | 0.299 | 0.273938319068 | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/H | 28118 |
Fn3-92 |
64 | rs72648220 |
0.0963 | -0.514 | 1.0 | N | 0.585 | 0.299 | 0.273938319068 |
Begay (2015)
| None |
DCM
|
het | None | None | I | WGS prioritisation; filtering with ANNOVAR; co-segregates within family (n = 2, 2 affected (total 2)) | None | None | None | None | None | None | None | None | None | None | None |
| R/H | 28118 |
Fn3-92 |
64 | rs72648220 |
0.0963 | -0.514 | 1.0 | N | 0.585 | 0.299 | 0.273938319068 | gnomAD-4.0.0 | 1.85924E-05 | None | None | None | None | I | None | 5.33248E-05 | 1.0001E-04 | None | 0 | 0 | None | 0 | 0 | 1.61057E-05 | 0 | 1.60082E-05 |
| R/L | 28118 |
Fn3-92 |
64 | rs72648220 |
0.4121 | 0.319 | 0.998 | N | 0.544 | 0.324 | None | gnomAD-2.1.1 | 2.15E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.7E-05 | 0 |
| R/L | 28118 |
Fn3-92 |
64 | rs72648220 |
0.4121 | 0.319 | 0.998 | N | 0.544 | 0.324 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| R/L | 28118 |
Fn3-92 |
64 | rs72648220 |
0.4121 | 0.319 | 0.998 | N | 0.544 | 0.324 | None | gnomAD-4.0.0 | 1.23959E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69533E-05 | 0 | 0 |
| R/P | 28118 |
Fn3-92 |
64 | None | 0.692 | None | 1.0 | N | 0.591 | 0.34 | 0.37550373646 | gnomAD-4.0.0 | 6.84312E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99526E-07 | 0 | 0 |
| G/S | 28218 |
Fn3-93 |
65 | rs727504693 |
0.0972 | -0.162 | 0.999 | N | 0.733 | 0.424 | 0.316788114976 | gnomAD-2.1.1 | 4.02E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 7.11E-05 | 0 |
| G/S | 28218 |
Fn3-93 |
65 | rs727504693 |
0.0972 | -0.162 | 0.999 | N | 0.733 | 0.424 | 0.316788114976 | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 1.20616E-04 | 1.31044E-04 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| G/S | 28218 |
Fn3-93 |
65 | rs727504693 |
0.0972 | -0.162 | 0.999 | N | 0.733 | 0.424 | 0.316788114976 | gnomAD-4.0.0 | 1.07213E-04 | None | None | None | None | N | None | 9.34305E-05 | 5.00167E-05 | None | 0 | 0 | None | 0 | 0 | 1.33078E-04 | 2.19602E-05 | 6.4041E-05 |
| E/K | 28316 |
Fn3-94 |
65 | None | 0.3763 | None | 0.285 | N | 0.314 | 0.241 | 0.258779203287 | gnomAD-4.0.0 | 6.84317E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99446E-07 | 0 | 0 |
| E/Q | 28316 |
Fn3-94 |
65 | rs183238138 |
0.2192 | 0.463 | 0.662 | N | 0.398 | 0.184 | None | gnomAD-2.1.1 | 3.58E-05 | None | None | None | None | N | None | 3.71962E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.40528E-04 |
| E/Q | 28316 |
Fn3-94 |
65 | rs183238138 |
0.2192 | 0.463 | 0.662 | N | 0.398 | 0.184 | None | gnomAD-3.1.2 | 9.86E-05 | None | None | None | None | N | None | 3.13646E-04 | 1.30959E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 28316 |
Fn3-94 |
65 | rs183238138 |
0.2192 | 0.463 | 0.662 | N | 0.398 | 0.184 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| E/Q | 28316 |
Fn3-94 |
65 | rs183238138 |
0.2192 | 0.463 | 0.662 | N | 0.398 | 0.184 | None | gnomAD-4.0.0 | 1.79727E-05 | None | None | None | None | N | None | 3.33156E-04 | 3.33311E-05 | None | 0 | 0 | None | 0 | 0 | 8.47601E-07 | 0 | 1.60087E-05 |
| K/N | 28514 |
Fn3-95 |
65 | None | 0.4951 | None | 0.967 | N | 0.492 | 0.204 | 0.159798565429 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/Q | 28514 |
Fn3-95 |
65 | rs1401382571 |
0.231 | 0.248 | 0.967 | N | 0.561 | 0.317 | 0.221734844693 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 28514 |
Fn3-95 |
65 | rs1401382571 |
0.231 | 0.248 | 0.967 | N | 0.561 | 0.317 | 0.221734844693 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93199E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 28514 |
Fn3-95 |
65 | rs1401382571 |
0.231 | 0.248 | 0.967 | N | 0.561 | 0.317 | 0.221734844693 | gnomAD-4.0.0 | 6.57134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93199E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 28714 |
Fn3-97 |
64 | rs532818379 |
0.3015 | -0.004 | 0.998 | D | 0.695 | 0.409 | 0.691364277267 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | N | None | 1.24069E-04 | 8.49E-05 | None | 0 | 0 | None | 9.81E-05 | None | 0 | 0 | 0 |
| G/R | 28714 |
Fn3-97 |
64 | rs532818379 |
0.3015 | -0.004 | 0.998 | D | 0.695 | 0.409 | 0.691364277267 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 1.31044E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 28714 |
Fn3-97 |
64 | rs532818379 |
0.3015 | -0.004 | 0.998 | D | 0.695 | 0.409 | 0.691364277267 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 0 | 2.9E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| G/R | 28714 |
Fn3-97 |
64 | rs532818379 |
0.3015 | -0.004 | 0.998 | D | 0.695 | 0.409 | 0.691364277267 | gnomAD-4.0.0 | 1.30139E-05 | None | None | None | None | N | None | 3.99925E-05 | 1.00007E-04 | None | 3.37815E-05 | 0 | None | 0 | 0 | 3.39043E-06 | 6.58819E-05 | 1.60087E-05 |
| N/S | 28908 |
Fn3-98 |
64 | rs377612718 |
0.0691 | 0.243 | 0.896 | N | 0.451 | 0.1 | None | gnomAD-2.1.1 | 1.06992E-04 | None | None | None | None | N | None | 2.89232E-04 | 4.80633E-04 | None | 0 | 0 | None | 0 | None | 0 | 4.68E-05 | 0 |
| N/S | 28908 |
Fn3-98 |
64 | rs377612718 |
0.0691 | 0.243 | 0.896 | N | 0.451 | 0.1 | None | gnomAD-3.1.2 | 1.90516E-04 | None | None | None | None | N | None | 3.8584E-04 | 5.89545E-04 | 0 | 0 | 1.9253E-04 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| N/S | 28908 |
Fn3-98 |
64 | rs377612718 |
0.0691 | 0.243 | 0.896 | N | 0.451 | 0.1 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| N/S | 28908 |
Fn3-98 |
64 | rs377612718 |
0.0691 | 0.243 | 0.896 | N | 0.451 | 0.1 | None | gnomAD-4.0.0 | 6.87824E-05 | None | None | None | None | N | None | 2.9313E-04 | 4.49955E-04 | None | 0 | 6.68568E-05 | None | 0 | 0 | 4.83166E-05 | 0 | 3.20102E-05 |
| G/R | 29004 |
Fn3-99 |
63 | None | 0.2073 | None | 0.994 | D | 0.807 | 0.443 | 0.569137904973 | gnomAD-4.0.0 | 1.23936E-06 | None | None | None | None | N | None | 1.33276E-05 | 0 | None | 0 | 2.23204E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 29004 |
Fn3-99 |
63 | rs761251825 |
0.0774 | -0.22 | 0.119 | D | 0.537 | 0.137 | 0.225902525712 | gnomAD-2.1.1 | 4.65E-05 | None | None | None | None | N | None | 1.23977E-04 | 8.49E-05 | None | 0 | 1.54337E-04 | None | 6.54E-05 | None | 0 | 1.57E-05 | 0 |
| G/S | 29004 |
Fn3-99 |
63 | rs761251825 |
0.0774 | -0.22 | 0.119 | D | 0.537 | 0.137 | 0.225902525712 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 9.65E-05 | 6.56E-05 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 1.47E-05 | 2.07555E-04 | 0 |
| G/S | 29004 |
Fn3-99 |
63 | rs761251825 |
0.0774 | -0.22 | 0.119 | D | 0.537 | 0.137 | 0.225902525712 | gnomAD-4.0.0 | 4.58598E-05 | None | None | None | None | N | None | 8.00961E-05 | 8.33778E-05 | None | 0 | 4.46289E-05 | None | 0 | 0 | 3.81418E-05 | 1.20789E-04 | 8.00538E-05 |
| T/I | 29301 |
Fn3-101 |
65 | None | 0.2947 | None | 0.669 | N | 0.419 | 0.177 | 0.362160248664 | gnomAD-4.0.0 | 1.36832E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79883E-06 | 0 | 0 |
| T/K | 29301 |
Fn3-101 |
65 | rs780957474 |
0.2416 | 0.092 | 0.801 | N | 0.379 | 0.256 | 0.3085936734 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/K | 29301 |
Fn3-101 |
65 | rs780957474 |
0.2416 | 0.092 | 0.801 | N | 0.379 | 0.256 | 0.3085936734 | gnomAD-4.0.0 | 6.8416E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| G/A | 29399 |
Fn3-102 |
65 | rs1701744078 |
0.3039 | None | 1.0 | N | 0.694 | 0.406 | 0.243972157842 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 29399 |
Fn3-102 |
65 | rs1701744078 |
0.3039 | None | 1.0 | N | 0.694 | 0.406 | 0.243972157842 | gnomAD-4.0.0 | 2.56222E-06 | None | None | None | None | I | None | 3.38215E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 29799 |
Fn3-105 |
66 | None | 0.0776 | None | None | N | 0.154 | 0.098 | 0.134241683229 | gnomAD-4.0.0 | 1.20046E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31266E-06 | 0 | 0 |
| N/S | 29799 |
Fn3-105 |
66 | None | 0.0752 | None | None | N | 0.174 | 0.111 | 0.0954503805726 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| N/T | 29799 |
Fn3-105 |
66 | rs371949055 |
0.1154 | 0.286 | 0.062 | N | 0.289 | 0.075 | None | gnomAD-2.1.1 | 6.37E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.29702E-04 | 0 |
| N/T | 29799 |
Fn3-105 |
66 | rs371949055 |
0.1154 | 0.286 | 0.062 | N | 0.289 | 0.075 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| N/T | 29799 |
Fn3-105 |
66 | rs371949055 |
0.1154 | 0.286 | 0.062 | N | 0.289 | 0.075 | None | gnomAD-4.0.0 | 1.31413E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.93962E-05 | 0 | 0 |
| N/T | 30288 |
Fn3-108 |
65 | rs763525672 |
0.272 | 0.282 | 0.999 | N | 0.683 | 0.551 | 0.500303608228 | gnomAD-2.1.1 | 3.22E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.11E-05 | 0 |
| N/T | 30288 |
Fn3-108 |
65 | rs763525672 |
0.272 | 0.282 | 0.999 | N | 0.683 | 0.551 | 0.500303608228 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/T | 30288 |
Fn3-108 |
65 | rs763525672 |
0.272 | 0.282 | 0.999 | N | 0.683 | 0.551 | 0.500303608228 | gnomAD-4.0.0 | 1.0536E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35626E-05 | 0 | 1.60138E-05 |
| G/R | 30485 |
Fn3-110 |
64 | rs748001852 |
0.7377 | -0.101 | 1.0 | N | 0.767 | 0.44 | 0.637519714765 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| G/R | 30485 |
Fn3-110 |
64 | rs748001852 |
0.7377 | -0.101 | 1.0 | N | 0.767 | 0.44 | 0.637519714765 | gnomAD-4.0.0 | 1.59231E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85961E-06 | 0 | 0 |
| G/C | 30784 |
Fn3-112 |
66 | rs979303656 |
0.268 | -0.547 | 0.997 | D | 0.674 | 0.448 | 0.575514189583 | gnomAD-2.1.1 | 6.37E-05 | None | None | None | None | N | None | 2.29463E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/C | 30784 |
Fn3-112 |
66 | rs979303656 |
0.268 | -0.547 | 0.997 | D | 0.674 | 0.448 | 0.575514189583 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/C | 30784 |
Fn3-112 |
66 | rs979303656 |
0.268 | -0.547 | 0.997 | D | 0.674 | 0.448 | 0.575514189583 | gnomAD-4.0.0 | 1.31427E-05 | None | None | None | None | N | None | 4.82532E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 30784 |
Fn3-112 |
66 | rs979303656 |
0.6283 | -0.101 | 0.942 | N | 0.595 | 0.379 | 0.481246930725 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 8.27E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/R | 30784 |
Fn3-112 |
66 | rs979303656 |
0.6283 | -0.101 | 0.942 | N | 0.595 | 0.379 | 0.481246930725 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20633E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 30784 |
Fn3-112 |
66 | rs979303656 |
0.6283 | -0.101 | 0.942 | N | 0.595 | 0.379 | 0.481246930725 | gnomAD-4.0.0 | 4.33758E-06 | None | None | None | None | N | None | 8.00961E-05 | 1.66689E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 31175 |
Fn3-115 |
63 | rs766346925 |
0.1248 | -0.212 | 0.983 | N | 0.395 | 0.245 | None | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.87E-06 | 0 |
| R/C | 31175 |
Fn3-115 |
63 | rs766346925 |
0.1248 | -0.212 | 0.983 | N | 0.395 | 0.245 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 31175 |
Fn3-115 |
63 | rs766346925 |
0.1248 | -0.212 | 0.983 | N | 0.395 | 0.245 | None | gnomAD-4.0.0 | 3.7182E-06 | None | None | None | None | N | None | 1.3354E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54282E-06 | 1.09794E-05 | 1.60102E-05 |
| R/H | 31175 |
Fn3-115 |
63 | rs72648251 |
0.0671 | -0.521 | 0.002 | N | 0.257 | 0.105 | None | gnomAD-2.1.1 | 4.31563E-04 | None | None | None | None | N | None | 1.23998E-04 | 5.65E-05 | None | 0 | 2.04876E-04 | None | 3.27E-05 | None | 9.99121E-04 | 6.55339E-04 | 2.80505E-04 |
| R/H | 31175 |
Fn3-115 |
63 | rs72648251 |
0.0671 | -0.521 | 0.002 | N | 0.257 | 0.105 | None | gnomAD-3.1.2 | 2.95792E-04 | None | None | None | None | N | None | 2.41359E-04 | 0 | 0 | 0 | 0 | None | 1.88324E-04 | 0 | 4.85223E-04 | 0 | 0 |
| R/H | 31175 |
Fn3-115 |
63 | rs72648251 |
0.0671 | -0.521 | 0.002 | N | 0.257 | 0.105 | None | gnomAD-4.0.0 | 4.41832E-04 | None | None | None | None | N | None | 1.60209E-04 | 5.00067E-05 | None | 0 | 8.91186E-05 | None | 7.96626E-04 | 0 | 5.29754E-04 | 2.19563E-05 | 2.56189E-04 |
| R/S | 31175 |
Fn3-115 |
63 | rs766346925 |
0.1412 | -0.172 | 0.002 | N | 0.201 | 0.139 | 0.176091768786 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| R/S | 31175 |
Fn3-115 |
63 | rs766346925 |
0.1412 | -0.172 | 0.002 | N | 0.201 | 0.139 | 0.176091768786 | gnomAD-4.0.0 | 6.84181E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99455E-07 | 0 | 0 |
| H/L | 31372 |
Fn3-116 |
65 | rs761630773 |
0.3188 | 0.729 | 0.968 | N | 0.521 | 0.319 | 0.347659731818 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| H/L | 31372 |
Fn3-116 |
65 | rs761630773 |
0.3188 | 0.729 | 0.968 | N | 0.521 | 0.319 | 0.347659731818 | gnomAD-4.0.0 | 2.0529E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79899E-06 | 0 | 1.65689E-05 |
| H/R | 31372 |
Fn3-116 |
65 | rs761630773 |
0.1804 | -0.054 | 0.026 | N | 0.279 | 0.176 | 0.168933306366 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 0 | 8.71E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| H/R | 31372 |
Fn3-116 |
65 | rs761630773 |
0.1804 | -0.054 | 0.026 | N | 0.279 | 0.176 | 0.168933306366 | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | I | None | 0 | 3.92876E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/R | 31372 |
Fn3-116 |
65 | rs761630773 |
0.1804 | -0.054 | 0.026 | N | 0.279 | 0.176 | 0.168933306366 | gnomAD-4.0.0 | 6.19749E-06 | None | None | None | None | I | None | 0 | 1.50055E-04 | None | 0 | 0 | None | 0 | 0 | 8.47629E-07 | 0 | 0 |
| H/Y | 31372 |
Fn3-116 |
65 | rs1349108221 |
0.1846 | None | 0.982 | N | 0.482 | 0.407 | 0.279776271856 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/Y | 31372 |
Fn3-116 |
65 | rs1349108221 |
0.1846 | None | 0.982 | N | 0.482 | 0.407 | 0.279776271856 | gnomAD-4.0.0 | 2.56291E-06 | None | None | None | None | I | None | 1.69165E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39329E-06 | 0 | 0 |
| G/S | 31472 |
Fn3-117 |
65 | rs1331080177 |
0.0971 | -0.38 | 0.489 | N | 0.141 | 0.244 | 0.180583059064 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/S | 31472 |
Fn3-117 |
65 | rs1331080177 |
0.0971 | -0.38 | 0.489 | N | 0.141 | 0.244 | 0.180583059064 | gnomAD-4.0.0 | 2.05263E-06 | None | None | None | None | N | None | 2.98846E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.31863E-05 | 0 |
| A/T | 31573 |
Fn3-118 |
68 | rs1175642523 |
0.2828 | -0.262 | 0.852 | N | 0.344 | 0.199 | 0.225902525712 | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| A/T | 31573 |
Fn3-118 |
68 | rs1175642523 |
0.2828 | -0.262 | 0.852 | N | 0.344 | 0.199 | 0.225902525712 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| A/T | 31573 |
Fn3-118 |
68 | rs1175642523 |
0.2828 | -0.262 | 0.852 | N | 0.344 | 0.199 | 0.225902525712 | gnomAD-4.0.0 | 3.09847E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.23812E-06 | 0 | 0 |
| R/K | 31771 |
Fn3-119 |
64 | rs397517760 |
0.1118 | 0.052 | 0.001 | N | 0.212 | 0.084 | 0.124217242631 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | I | None | 1.29132E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/K | 31771 |
Fn3-119 |
64 | rs397517760 |
0.1118 | 0.052 | 0.001 | N | 0.212 | 0.084 | 0.124217242631 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 7.24E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 31771 |
Fn3-119 |
64 | rs397517760 |
0.1118 | 0.052 | 0.001 | N | 0.212 | 0.084 | 0.124217242631 | gnomAD-4.0.0 | 1.9714E-05 | None | None | None | None | I | None | 7.23729E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 31872 |
Fn3-120 |
66 | None | 0.0451 | None | None | N | 0.089 | 0.071 | 0.0297737177859 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| S/R | 31872 |
Fn3-120 |
66 | rs757129504 |
0.5362 | 0.091 | 0.055 | N | 0.452 | 0.052 | 0.19670166235 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| S/R | 31872 |
Fn3-120 |
66 | rs757129504 |
0.5362 | 0.091 | 0.055 | N | 0.452 | 0.052 | 0.19670166235 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/R | 31872 |
Fn3-120 |
66 | rs757129504 |
0.5362 | 0.091 | 0.055 | N | 0.452 | 0.052 | 0.19670166235 | gnomAD-4.0.0 | 6.01193E-05 | None | None | None | None | N | None | 1.33515E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 7.96871E-05 | 0 | 3.20266E-05 |
| S/T | 31872 |
Fn3-120 |
66 | rs1696652076 |
0.0989 | None | 0.024 | N | 0.336 | 0.08 | 0.0666544352282 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| S/T | 31872 |
Fn3-120 |
66 | rs1696652076 |
0.0989 | None | 0.024 | N | 0.336 | 0.08 | 0.0666544352282 | gnomAD-4.0.0 | 6.57168E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| D/E | 31974 |
Fn3-121 |
66 | rs1239268108 |
0.1233 | 0.11 | 0.007 | N | 0.17 | 0.106 | 0.0482279557977 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| D/E | 31974 |
Fn3-121 |
66 | rs1239268108 |
0.1233 | 0.11 | 0.007 | N | 0.17 | 0.106 | 0.0482279557977 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02444E-05 |
| D/G | 31974 |
Fn3-121 |
66 | rs1441974085 |
0.0841 | 0.075 | 0.001 | N | 0.233 | 0.208 | 0.119812018005 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/G | 31974 |
Fn3-121 |
66 | rs1441974085 |
0.0841 | 0.075 | 0.001 | N | 0.233 | 0.208 | 0.119812018005 | gnomAD-4.0.0 | 1.59138E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| G/E | 32168 |
Fn3-122 |
64 | rs745694652 |
0.3168 | -0.057 | 1.0 | N | 0.757 | 0.426 | 0.48095081912 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 1.66223E-04 |
| G/E | 32168 |
Fn3-122 |
64 | rs745694652 |
0.3168 | -0.057 | 1.0 | N | 0.757 | 0.426 | 0.48095081912 | gnomAD-4.0.0 | 4.10544E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49737E-06 | 0 | 1.65678E-05 |
| G/R | 32168 |
Fn3-122 |
64 | rs1381527063 |
0.4885 | -0.058 | 1.0 | N | 0.774 | 0.433 | 0.616854986462 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| G/R | 32168 |
Fn3-122 |
64 | rs1381527063 |
0.4885 | -0.058 | 1.0 | N | 0.774 | 0.433 | 0.616854986462 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/R | 32168 |
Fn3-122 |
64 | rs1381527063 |
0.4885 | -0.058 | 1.0 | N | 0.774 | 0.433 | 0.616854986462 | gnomAD-4.0.0 | 1.31442E-05 | None | None | None | None | N | None | 2.41359E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47011E-05 | 0 | 0 |
| S/F | 32266 |
Fn3-123 |
65 | rs773092840 |
0.2685 | -0.865 | 1.0 | N | 0.689 | 0.401 | 0.624938293356 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.56E-05 | None | 0 | None | 0 | 0 | 0 |
| S/F | 32266 |
Fn3-123 |
65 | rs773092840 |
0.2685 | -0.865 | 1.0 | N | 0.689 | 0.401 | 0.624938293356 | gnomAD-4.0.0 | 1.59146E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77331E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 32266 |
Fn3-123 |
65 | rs933521240 |
0.4842 | -0.518 | 1.0 | N | 0.661 | 0.525 | 0.270889551736 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| S/P | 32266 |
Fn3-123 |
65 | rs933521240 |
0.4842 | -0.518 | 1.0 | N | 0.661 | 0.525 | 0.270889551736 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 0 | 0 |
| S/P | 32266 |
Fn3-123 |
65 | rs933521240 |
0.4842 | -0.518 | 1.0 | N | 0.661 | 0.525 | 0.270889551736 | gnomAD-4.0.0 | 4.95865E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78159E-06 | 0 | 0 |
| R/G | 32463 |
Fn3-124 |
65 | rs1398002611 |
0.326 | -0.055 | 0.896 | N | 0.481 | 0.196 | 0.263612267334 | gnomAD-2.1.1 | 9.56E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.94578E-04 | 0 |
| R/G | 32463 |
Fn3-124 |
65 | rs1398002611 |
0.326 | -0.055 | 0.896 | N | 0.481 | 0.196 | 0.263612267334 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/G | 32463 |
Fn3-124 |
65 | rs1398002611 |
0.326 | -0.055 | 0.896 | N | 0.481 | 0.196 | 0.263612267334 | gnomAD-4.0.0 | 5.12568E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.57391E-06 | 0 | 0 |
| R/K | 32463 |
Fn3-124 |
65 | rs1257117887 |
0.1579 | -0.073 | 0.011 | N | 0.215 | 0.115 | 0.104622674875 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| R/K | 32463 |
Fn3-124 |
65 | rs1257117887 |
0.1579 | -0.073 | 0.011 | N | 0.215 | 0.115 | 0.104622674875 | gnomAD-4.0.0 | 3.18322E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71755E-06 | 0 | 0 |
| G/D | 32563 |
Fn3-125 |
65 | rs1268910714 |
0.3456 | 0.119 | 1.0 | N | 0.742 | 0.436 | 0.310458034454 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/D | 32563 |
Fn3-125 |
65 | rs1268910714 |
0.3456 | 0.119 | 1.0 | N | 0.742 | 0.436 | 0.310458034454 | gnomAD-4.0.0 | 1.59747E-06 | None | None | None | None | N | None | 0 | 2.29716E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| H/Q | 32664 |
Fn3-126 |
65 | rs794729549 |
0.3222 | None | 1.0 | N | 0.703 | 0.22 | 0.146414634003 | gnomAD-4.0.0 | 8.21042E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.02267E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 32859 |
Fn3-127 |
65 | rs370747109 |
0.4993 | -0.023 | 0.991 | N | 0.627 | 0.332 | 0.180583059064 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| G/A | 32859 |
Fn3-127 |
65 | rs370747109 |
0.4993 | -0.023 | 0.991 | N | 0.627 | 0.332 | 0.180583059064 | gnomAD-4.0.0 | 2.73674E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 5.20291E-04 | 0 | 0 | 1.65645E-05 |
| G/D | 32859 |
Fn3-127 |
65 | rs370747109 |
0.5949 | -0.186 | 0.45 | N | 0.505 | 0.306 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/D | 32859 |
Fn3-127 |
65 | rs370747109 |
0.5949 | -0.186 | 0.45 | N | 0.505 | 0.306 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 32859 |
Fn3-127 |
65 | rs370747109 |
0.5949 | -0.186 | 0.45 | N | 0.505 | 0.306 | None | gnomAD-4.0.0 | 1.85914E-06 | None | None | None | None | N | None | 2.67173E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.09794E-05 | 0 |
| G/S | 32859 |
Fn3-127 |
65 | rs747772240 |
0.3704 | -0.449 | 0.997 | N | 0.739 | 0.423 | 0.1749357433 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| G/S | 32859 |
Fn3-127 |
65 | rs747772240 |
0.3704 | -0.449 | 0.997 | N | 0.739 | 0.423 | 0.1749357433 | gnomAD-4.0.0 | 1.59114E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85817E-06 | 0 | 0 |
| G/V | 32859 |
Fn3-127 |
65 | None | 0.7657 | None | 0.999 | N | 0.777 | 0.487 | 0.670683552153 | gnomAD-4.0.0 | 6.84185E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99459E-07 | 0 | 0 |
| G/E | 32961 |
Fn3-128 |
66 | rs1225559660 |
0.8398 | -0.46 | 1.0 | N | 0.768 | 0.508 | 0.515995215087 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/E | 32961 |
Fn3-128 |
66 | rs1225559660 |
0.8398 | -0.46 | 1.0 | N | 0.768 | 0.508 | 0.515995215087 | gnomAD-4.0.0 | 3.18268E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86558E-05 | 0 |
| G/A | 33062 |
Fn3-129 |
65 | None | 0.1842 | None | 1.0 | N | 0.703 | 0.395 | 0.306053231325 | gnomAD-4.0.0 | 9.60271E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.05002E-05 | 0 | 0 |
| N/T | 33355 |
Fn3-130 |
66 | None | 0.4241 | None | 0.998 | N | 0.585 | 0.497 | 0.355865052028 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/S | 33456 |
Fn3-131 |
65 | None | 0.1111 | None | 0.625 | N | 0.356 | 0.178 | 0.148003135375 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/Y | 33456 |
Fn3-131 |
65 | None | 0.1981 | None | 0.989 | N | 0.427 | 0.404 | 0.541149246611 | gnomAD-4.0.0 | 1.59152E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02425E-05 |
| N/H | 33751 |
Fn3-132 |
63 | rs753658469 |
0.2842 | -0.187 | 0.999 | N | 0.668 | 0.522 | None | gnomAD-2.1.1 | 2.85E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.24E-05 | 0 |
| N/H | 33751 |
Fn3-132 |
63 | rs753658469 |
0.2842 | -0.187 | 0.999 | N | 0.668 | 0.522 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.02878E-04 | 0 | 0 |
| N/H | 33751 |
Fn3-132 |
63 | rs753658469 |
0.2842 | -0.187 | 0.999 | N | 0.668 | 0.522 | None | gnomAD-4.0.0 | 2.78835E-05 | None | None | None | None | N | None | 1.33444E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.64448E-05 | 0 | 1.60087E-05 |
| N/S | 33751 |
Fn3-132 |
63 | rs1475672598 |
0.0956 | 0.154 | 0.98 | N | 0.533 | 0.288 | 0.28798054836 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/S | 33751 |
Fn3-132 |
63 | rs1475672598 |
0.0956 | 0.154 | 0.98 | N | 0.533 | 0.288 | 0.28798054836 | gnomAD-4.0.0 | 1.59107E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8578E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.