Structural position:
- Domain Type: Ig
- Aligned Position: 130
- Secondary Structure Element: e
- Secondary Structure Region: β-strand D
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S/R | 59 |
Ig-1 |
54 | rs191057824 |
0.438 | 0.249 | 1.0 | N | 0.649 | 0.528 | 0.460795861206 | gnomAD-2.1.1 | 5.31E-05 | None | None | None | -0.455(TCAP) | N | None | 4.01E-05 | 5.64E-05 | None | 0 | 0 | None | 0 | None | 0 | 9.3E-05 | 0 |
| S/R | 59 |
Ig-1 |
54 | rs191057824 |
0.438 | 0.249 | 1.0 | N | 0.649 | 0.528 | 0.460795861206 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | -0.455(TCAP) | N | None | 7.24E-05 | 6.54E-05 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| S/R | 59 |
Ig-1 |
54 | rs191057824 |
0.438 | 0.249 | 1.0 | N | 0.649 | 0.528 | 0.460795861206 | gnomAD-4.0.0 | 8.86006E-05 | None | None | None | -0.455(TCAP) | N | None | 4.00513E-05 | 8.33278E-05 | None | 0 | 0 | None | 0 | 0 | 1.09321E-04 | 0 | 9.60215E-05 |
| E/Q | 155 |
Ig-2 |
52 | rs1429805491 |
0.2811 | 0.676 | 0.623 | N | 0.35 | 0.205 | 0.266385636622 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | -1.009(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/Q | 155 |
Ig-2 |
52 | rs1429805491 |
0.2811 | 0.676 | 0.623 | N | 0.35 | 0.205 | 0.266385636622 | gnomAD-4.0.0 | 1.59045E-06 | None | None | None | -1.009(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| Q/R | 994 |
Ig-3 |
52 | None | 0.1055 | None | None | N | 0.229 | 0.151 | 0.12205267543 | gnomAD-4.0.0 | 1.59054E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8566E-06 | 0 | 0 |
| N/S | 1133 |
Ig-4 |
52 | rs775192919 |
0.1048 | -0.512 | 0.027 | N | 0.329 | 0.146 | 0.198526703765 | gnomAD-2.1.1 | 1.99E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63345E-04 | None | 0 | 0 | 0 |
| N/S | 1133 |
Ig-4 |
52 | rs775192919 |
0.1048 | -0.512 | 0.027 | N | 0.329 | 0.146 | 0.198526703765 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14079E-04 | 0 |
| N/S | 1133 |
Ig-4 |
52 | rs775192919 |
0.1048 | -0.512 | 0.027 | N | 0.329 | 0.146 | 0.198526703765 | gnomAD-4.0.0 | 4.60988E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.82444E-04 | 0 |
| Q/R | 1343 |
Ig-5 |
53 | None | 0.1391 | None | 0.004 | N | 0.206 | 0.107 | 0.0762999501168 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/A | 1509 |
Ig-6 |
53 | rs794729575 |
0.7413 | None | 0.999 | D | 0.575 | 0.634 | 0.543561272632 | gnomAD-4.0.0 | 1.36832E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79868E-06 | 0 | 0 |
| E/G | 1509 |
Ig-6 |
53 | rs794729575 |
0.7128 | -0.086 | 1.0 | D | 0.569 | 0.67 | 0.567747928639 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.82E-06 | 0 |
| E/G | 1509 |
Ig-6 |
53 | rs794729575 |
0.7128 | -0.086 | 1.0 | D | 0.569 | 0.67 | 0.567747928639 | gnomAD-4.0.0 | 7.52574E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.89276E-06 | 0 | 0 |
| E/K | 1509 |
Ig-6 |
53 | rs1270432206 |
0.8492 | 0.698 | 0.999 | D | 0.605 | 0.593 | 0.521173705876 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| E/K | 1509 |
Ig-6 |
53 | rs1270432206 |
0.8492 | 0.698 | 0.999 | D | 0.605 | 0.593 | 0.521173705876 | gnomAD-4.0.0 | 6.8162E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32237E-06 | 0 | 0 |
| T/N | 1609 |
Ig-7 |
54 | None | 0.0904 | None | 0.949 | N | 0.417 | 0.126 | 0.195762928549 | gnomAD-4.0.0 | 6.84137E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99321E-07 | 0 | 0 |
| E/K | 2130 |
Ig-10 |
53 | rs762914675 |
0.5558 | -0.316 | 1.0 | D | 0.578 | 0.529 | None | gnomAD-2.1.1 | 4.38E-05 | None | None | None | None | N | None | 0 | 8.69E-05 | None | 0 | 5.46E-05 | None | 1.30668E-04 | None | 0 | 2.64E-05 | 0 |
| E/K | 2130 |
Ig-10 |
53 | rs762914675 |
0.5558 | -0.316 | 1.0 | D | 0.578 | 0.529 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 2130 |
Ig-10 |
53 | rs762914675 |
0.5558 | -0.316 | 1.0 | D | 0.578 | 0.529 | None | gnomAD-4.0.0 | 1.92087E-05 | None | None | None | None | N | None | 1.33518E-05 | 5.003E-05 | None | 0 | 4.4611E-05 | None | 0 | 0 | 1.18645E-05 | 9.88121E-05 | 3.20102E-05 |
| D/N | 2225 |
Ig-11 |
52 | None | 0.5048 | None | 1.0 | D | 0.617 | 0.458 | 0.36036328697 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/C | 2317 |
Ig-12 |
51 | rs750101152 |
0.422 | -0.295 | 1.0 | N | 0.723 | 0.536 | 0.752996958338 | gnomAD-2.1.1 | 1.99E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 2.65E-05 | 0 |
| R/C | 2317 |
Ig-12 |
51 | rs750101152 |
0.422 | -0.295 | 1.0 | N | 0.723 | 0.536 | 0.752996958338 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/C | 2317 |
Ig-12 |
51 | rs750101152 |
0.422 | -0.295 | 1.0 | N | 0.723 | 0.536 | 0.752996958338 | gnomAD-4.0.0 | 2.35448E-05 | None | None | None | None | N | None | 1.33508E-05 | 0 | None | 0 | 0 | None | 0 | 1.64366E-04 | 2.7119E-05 | 2.19606E-05 | 3.20072E-05 |
| R/H | 2317 |
Ig-12 |
51 | rs764882950 |
0.1999 | -0.963 | 1.0 | N | 0.73 | 0.435 | 0.346315397577 | gnomAD-2.1.1 | 6.02E-05 | None | None | None | None | N | None | 1.20163E-04 | 2.54137E-04 | None | 0 | 5.02E-05 | None | 6.53E-05 | None | 0 | 1.55E-05 | 0 |
| R/H | 2317 |
Ig-12 |
51 | rs764882950 |
0.1999 | -0.963 | 1.0 | N | 0.73 | 0.435 | 0.346315397577 | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 7.24E-05 | 5.24384E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/H | 2317 |
Ig-12 |
51 | rs764882950 |
0.1999 | -0.963 | 1.0 | N | 0.73 | 0.435 | 0.346315397577 | gnomAD-4.0.0 | 2.72607E-05 | None | None | None | None | N | None | 1.33305E-04 | 2.83371E-04 | None | 0 | 2.22777E-05 | None | 0 | 0 | 1.18647E-05 | 2.19597E-05 | 0 |
| R/L | 2317 |
Ig-12 |
51 | rs764882950 |
0.5281 | None | 1.0 | N | 0.626 | 0.549 | 0.65596759018 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/L | 2317 |
Ig-12 |
51 | rs764882950 |
0.5281 | None | 1.0 | N | 0.626 | 0.549 | 0.65596759018 | gnomAD-4.0.0 | 1.23921E-06 | None | None | None | None | N | None | 1.33522E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47471E-07 | 0 | 0 |
| R/S | 2317 |
Ig-12 |
51 | rs750101152 |
0.8029 | None | 1.0 | N | 0.671 | 0.533 | 0.491455083755 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/S | 2317 |
Ig-12 |
51 | rs750101152 |
0.8029 | None | 1.0 | N | 0.671 | 0.533 | 0.491455083755 | gnomAD-4.0.0 | 6.57289E-06 | None | None | None | None | N | None | 2.41371E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 2406 |
Ig-13 |
51 | rs772454567 |
0.6654 | 0.192 | 1.0 | D | 0.447 | 0.535 | 0.543209242439 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| D/E | 2406 |
Ig-13 |
51 | rs772454567 |
0.6654 | 0.192 | 1.0 | D | 0.447 | 0.535 | 0.543209242439 | gnomAD-4.0.0 | 1.59052E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| D/G | 2406 |
Ig-13 |
51 | rs2091891924 |
0.7364 | None | 1.0 | D | 0.649 | 0.717 | 0.562617508568 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 2406 |
Ig-13 |
51 | rs2091891924 |
0.7364 | None | 1.0 | D | 0.649 | 0.717 | 0.562617508568 | gnomAD-4.0.0 | 2.56126E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.7837E-06 | 0 | 0 |
| D/N | 2406 |
Ig-13 |
51 | None | 0.4926 | None | 1.0 | D | 0.635 | 0.583 | 0.499218193508 | gnomAD-4.0.0 | 1.59052E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| H/R | 2583 |
Ig-15 |
51 | rs2091790336 |
0.0603 | None | None | N | 0.097 | 0.099 | 0.112648838833 | gnomAD-4.0.0 | 1.36838E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79871E-06 | 0 | 0 |
| H/Y | 2583 |
Ig-15 |
51 | rs367582681 |
0.1019 | 1.022 | 0.391 | N | 0.325 | 0.161 | None | gnomAD-2.1.1 | 7.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.47E-05 | None | 0 | None | 0 | 8.84E-06 | 0 |
| H/Y | 2583 |
Ig-15 |
51 | rs367582681 |
0.1019 | 1.022 | 0.391 | N | 0.325 | 0.161 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/Y | 2583 |
Ig-15 |
51 | rs367582681 |
0.1019 | 1.022 | 0.391 | N | 0.325 | 0.161 | None | gnomAD-4.0.0 | 3.09888E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.46389E-05 | None | 0 | 0 | 1.69505E-06 | 0 | 1.60082E-05 |
| D/N | 2670 |
Ig-16 |
50 | rs1344075805 |
0.0871 | None | 0.015 | N | 0.173 | 0.2 | 0.264547087235 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 2758 |
Ig-17 |
52 | rs748372588 |
0.0872 | 0.25 | 0.801 | D | 0.363 | 0.433 | 0.422404719673 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 5.78E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/R | 2758 |
Ig-17 |
52 | rs748372588 |
0.0872 | 0.25 | 0.801 | D | 0.363 | 0.433 | 0.422404719673 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| K/R | 2758 |
Ig-17 |
52 | rs748372588 |
0.0872 | 0.25 | 0.801 | D | 0.363 | 0.433 | 0.422404719673 | gnomAD-4.0.0 | 6.40277E-06 | None | None | None | None | N | None | 1.69102E-05 | 5.08354E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84204E-05 |
| K/T | 2758 |
Ig-17 |
52 | None | 0.092 | None | 0.801 | D | 0.415 | 0.58 | 0.579989844333 | gnomAD-4.0.0 | 1.59049E-06 | None | None | None | None | N | None | 0 | 2.28645E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 2932 |
Ig-19 |
51 | rs1490705975 |
0.3512 | 0.568 | 0.997 | N | 0.501 | 0.468 | 0.263612267334 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| Q/R | 2932 |
Ig-19 |
51 | rs1490705975 |
0.3512 | 0.568 | 0.997 | N | 0.501 | 0.468 | 0.263612267334 | gnomAD-4.0.0 | 1.59048E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85652E-06 | 0 | 0 |
| K/R | 3019 |
Ig-20 |
51 | None | 0.0828 | None | 0.217 | N | 0.212 | 0.19 | 0.203808441222 | gnomAD-4.0.0 | 1.59058E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85651E-06 | 0 | 0 |
| E/D | 3108 |
Ig-21 |
51 | rs756206178 |
0.2865 | -0.39 | 0.999 | N | 0.424 | 0.264 | 0.233150807113 | gnomAD-2.1.1 | 1.06E-05 | None | None | None | None | N | None | 1.20163E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/D | 3108 |
Ig-21 |
51 | rs756206178 |
0.2865 | -0.39 | 0.999 | N | 0.424 | 0.264 | 0.233150807113 | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 1.68903E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 3108 |
Ig-21 |
51 | rs756206178 |
0.2865 | -0.39 | 0.999 | N | 0.424 | 0.264 | 0.233150807113 | gnomAD-4.0.0 | 8.67421E-06 | None | None | None | None | N | None | 1.86861E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 3199 |
Ig-22 |
53 | rs2090451326 |
0.8079 | None | 0.993 | D | 0.456 | 0.432 | 0.527251791467 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 3199 |
Ig-22 |
53 | rs2090451326 |
0.8079 | None | 0.993 | D | 0.456 | 0.432 | 0.527251791467 | gnomAD-4.0.0 | 6.56883E-06 | None | None | None | None | N | None | 2.4115E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 3290 |
Ig-23 |
52 | rs727503680 |
0.3581 | None | 0.619 | N | 0.255 | 0.22 | 0.362758974969 | gnomAD-4.0.0 | 6.84073E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99297E-06 | 0 | 0 |
| D/G | 3290 |
Ig-23 |
52 | rs2090030791 |
0.5276 | None | 0.996 | N | 0.602 | 0.629 | 0.48087575253 | gnomAD-4.0.0 | 1.59052E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85652E-06 | 0 | 0 |
| D/H | 3290 |
Ig-23 |
52 | rs750489067 |
0.6265 | 0.344 | 1.0 | D | 0.677 | 0.604 | 0.609617904835 | gnomAD-2.1.1 | 2.39E-05 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 3.53E-05 | 1.63185E-04 |
| D/H | 3290 |
Ig-23 |
52 | rs750489067 |
0.6265 | 0.344 | 1.0 | D | 0.677 | 0.604 | 0.609617904835 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/H | 3290 |
Ig-23 |
52 | rs750489067 |
0.6265 | 0.344 | 1.0 | D | 0.677 | 0.604 | 0.609617904835 | gnomAD-4.0.0 | 3.71752E-05 | None | None | None | None | N | None | 0 | 1.66667E-05 | None | 0 | 0 | None | 0 | 0 | 5E-05 | 0 | 0 |
| D/Y | 3290 |
Ig-23 |
52 | rs750489067 |
0.5866 | 0.322 | 1.0 | D | 0.713 | 0.653 | 0.806559599631 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.44E-05 | None | 0 | None | 0 | 0 | 0 |
| D/Y | 3290 |
Ig-23 |
52 | rs750489067 |
0.5866 | 0.322 | 1.0 | D | 0.713 | 0.653 | 0.806559599631 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 3290 |
Ig-23 |
52 | rs750489067 |
0.5866 | 0.322 | 1.0 | D | 0.713 | 0.653 | 0.806559599631 | gnomAD-4.0.0 | 1.23917E-06 | None | None | None | None | N | None | 1.3349E-05 | 0 | None | 0 | 2.22876E-05 | None | 0 | 0 | 0 | 0 | 0 |
| F/S | 3395 |
Ig-24 |
51 | None | 0.4594 | None | 1.0 | N | 0.623 | 0.628 | 0.788010845958 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/C | 3518 |
Ig-25 |
54 | rs1277243327 |
0.2525 | -0.01 | None | None | None | 0.165 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/C | 3518 |
Ig-25 |
54 | rs1277243327 |
0.2525 | -0.01 | None | None | None | 0.165 | None | gnomAD-4.0.0 | 1.59115E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43283E-05 | 0 |
| S/T | 3518 |
Ig-25 |
54 | rs745350155 |
0.0984 | 0.162 | None | None | None | 0.086 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| S/T | 3518 |
Ig-25 |
54 | rs745350155 |
0.0984 | 0.162 | None | None | None | 0.086 | None | gnomAD-4.0.0 | 3.18232E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71615E-06 | 0 | 0 |
| N/S | 3711 |
Ig-26 |
52 | None | 0.087 | None | None | None | None | 0.076 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| P/H | 3990 |
Ig-28 |
53 | rs33971253 |
0.1677 | None | 0.965 | N | 0.435 | 0.236 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/H | 3990 |
Ig-28 |
53 | rs33971253 |
0.1677 | None | 0.965 | N | 0.435 | 0.236 | None | gnomAD-4.0.0 | 1.2394E-06 | None | None | None | None | I | None | 1.33472E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60113E-05 |
| P/L | 3990 |
Ig-28 |
53 | rs33971253 |
0.1287 | 0.129 | 0.338 | N | 0.457 | 0.236 | None | gnomAD-2.1.1 | 6.42171E-03 | None | None | None | None | I | None | 2.64988E-03 | 3.19751E-03 | None | 3.96825E-03 | 0 | None | 5.55556E-04 | None | 2.88485E-03 | 1.13901E-02 | 4.77528E-03 |
| P/L | 3990 |
Ig-28 |
53 | rs33971253 |
0.1287 | 0.129 | 0.338 | N | 0.457 | 0.236 | None | gnomAD-3.1.2 | 6.40074E-03 | None | None | None | None | I | None | 2.46092E-03 | 2.81745E-03 | 0 | 2.88184E-03 | 0 | None | 2.07234E-03 | 0 | 1.14508E-02 | 1.44867E-03 | 5.25813E-03 |
| P/L | 3990 |
Ig-28 |
53 | rs33971253 |
0.1287 | 0.129 | 0.338 | N | 0.457 | 0.236 | None | 1000 genomes | 2.79553E-03 | None | None | None | None | I | None | 0 | 0 | None | None | 0 | 1.29E-02 | None | None | None | 1E-03 | None |
| P/L | 3990 |
Ig-28 |
53 | rs33971253 |
0.1287 | 0.129 | 0.338 | N | 0.457 | 0.236 | None | gnomAD-4.0.0 | 1.00365E-02 | None | None | None | None | I | None | 2.29199E-03 | 2.98343E-03 | None | 4.02E-03 | 0 | None | 3.66083E-03 | 4.94886E-04 | 1.26323E-02 | 5.5991E-04 | 8.56301E-03 |
| P/T | 3990 |
Ig-28 |
53 | None | 0.0885 | None | 0.003 | N | 0.304 | 0.087 | None | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43279E-05 | 0 |
| D/H | 4655 |
Ig-29 |
50 | rs1299692717 |
0.1647 | None | 0.782 | D | 0.429 | 0.359 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/H | 4655 |
Ig-29 |
50 | rs1299692717 |
0.1647 | None | 0.782 | D | 0.429 | 0.359 | None | gnomAD-4.0.0 | 2.48326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39635E-06 | 0 | 0 |
| D/N | 4655 |
Ig-29 |
50 | None | 0.0852 | None | 0.003 | D | 0.188 | 0.135 | None | gnomAD-4.0.0 | 6.85563E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01122E-07 | 0 | 0 |
| A/S | 4846 |
Ig-31 |
52 | rs752150323 |
0.0783 | 0.069 | None | N | 0.07 | 0.091 | 0.209622950755 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| A/T | 4846 |
Ig-31 |
52 | rs752150323 |
0.0681 | -0.024 | 0.064 | N | 0.259 | 0.114 | 0.255777322467 | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 0 | 1.97975E-04 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 1.40331E-04 |
| A/T | 4846 |
Ig-31 |
52 | rs752150323 |
0.0681 | -0.024 | 0.064 | N | 0.259 | 0.114 | 0.255777322467 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| A/T | 4846 |
Ig-31 |
52 | rs752150323 |
0.0681 | -0.024 | 0.064 | N | 0.259 | 0.114 | 0.255777322467 | gnomAD-4.0.0 | 3.71814E-05 | None | None | None | None | N | None | 1.33543E-05 | 1.83419E-04 | None | 0 | 0 | None | 0 | 0 | 3.55986E-05 | 2.19573E-05 | 6.40348E-05 |
| E/D | 4939 |
Ig-32 |
52 | None | 0.1505 | None | 0.998 | N | 0.376 | 0.184 | 0.479893544335 | gnomAD-4.0.0 | 1.59166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85843E-06 | 0 | 0 |
| E/Q | 4939 |
Ig-32 |
52 | rs2081311155 |
0.1208 | None | 0.996 | N | 0.511 | 0.307 | 0.518858945281 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/Q | 4939 |
Ig-32 |
52 | rs2081311155 |
0.1208 | None | 0.996 | N | 0.511 | 0.307 | 0.518858945281 | gnomAD-4.0.0 | 6.57134E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4699E-05 | 0 | 0 |
| V/I | 5033 |
Ig-33 |
53 | rs1296327328 |
0.0704 | None | 0.027 | N | 0.213 | 0.084 | 0.513787655203 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/K | 5126 |
Ig-34 |
52 | rs867299578 |
0.0837 | 0.042 | 0.248 | N | 0.193 | 0.233 | 0.152612264143 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Q/K | 5126 |
Ig-34 |
52 | rs867299578 |
0.0837 | 0.042 | 0.248 | N | 0.193 | 0.233 | 0.152612264143 | gnomAD-4.0.0 | 1.59148E-06 | None | None | None | None | N | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 5219 |
Ig-35 |
52 | rs759581032 |
0.3274 | -0.041 | 0.055 | N | 0.283 | 0.219 | 0.15556083564 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 5.79E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/P | 5219 |
Ig-35 |
52 | rs759581032 |
0.3274 | -0.041 | 0.055 | N | 0.283 | 0.219 | 0.15556083564 | gnomAD-4.0.0 | 3.18225E-06 | None | None | None | None | N | None | 0 | 4.57268E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 5501 |
Ig-38 |
52 | None | 0.1219 | None | 0.013 | N | 0.162 | 0.245 | 0.32580497728 | gnomAD-4.0.0 | 6.84262E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99489E-07 | 0 | 0 |
| V/M | 5595 |
Ig-39 |
53 | None | 0.0926 | None | 0.002 | D | 0.188 | 0.108 | 0.358540694251 | gnomAD-4.0.0 | 1.59122E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85825E-06 | 0 | 0 |
| Q/H | 5688 |
Ig-40 |
52 | rs1314251790 |
0.163 | -0.265 | 0.927 | D | 0.261 | 0.285 | 0.348764635752 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| Q/H | 5688 |
Ig-40 |
52 | rs1314251790 |
0.163 | -0.265 | 0.927 | D | 0.261 | 0.285 | 0.348764635752 | gnomAD-4.0.0 | 3.1825E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71677E-06 | 0 | 0 |
| Q/L | 5688 |
Ig-40 |
52 | None | 0.1593 | None | 0.27 | N | 0.265 | 0.305 | 0.488477830397 | gnomAD-4.0.0 | 6.84205E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| Q/R | 5688 |
Ig-40 |
52 | None | 0.0856 | None | 0.642 | N | 0.159 | 0.257 | 0.180583059064 | gnomAD-4.0.0 | 1.36841E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79896E-06 | 0 | 0 |
| E/G | 5781 |
Ig-41 |
52 | rs1414405507 |
0.2229 | -0.312 | 0.801 | N | 0.434 | 0.361 | 0.42573502686 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| E/K | 5781 |
Ig-41 |
52 | rs1400453149 |
0.1427 | 0.815 | 0.005 | N | 0.124 | 0.246 | 0.236890367714 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 6.4433E-04 | None | 0 | None | 0 | 0 | 0 |
| E/K | 5781 |
Ig-41 |
52 | rs1400453149 |
0.1427 | 0.815 | 0.005 | N | 0.124 | 0.246 | 0.236890367714 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.93125E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 5781 |
Ig-41 |
52 | rs1400453149 |
0.1427 | 0.815 | 0.005 | N | 0.124 | 0.246 | 0.236890367714 | gnomAD-4.0.0 | 6.5741E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 1.93125E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/Q | 5781 |
Ig-41 |
52 | None | 0.1116 | None | 0.801 | D | 0.343 | 0.168 | 0.283761946502 | gnomAD-4.0.0 | 1.59125E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85814E-06 | 0 | 0 |
| T/P | 5874 |
Ig-42 |
52 | None | 0.421 | None | 0.991 | N | 0.529 | 0.352 | 0.561485227407 | gnomAD-4.0.0 | 3.18291E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71736E-06 | 0 | 0 |
| H/P | 5970 |
Ig-43 |
52 | rs539871760 |
0.6571 | 0.68 | 0.822 | N | 0.35 | 0.259 | 0.42324137094 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| H/P | 5970 |
Ig-43 |
52 | rs539871760 |
0.6571 | 0.68 | 0.822 | N | 0.35 | 0.259 | 0.42324137094 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| H/P | 5970 |
Ig-43 |
52 | rs539871760 |
0.6571 | 0.68 | 0.822 | N | 0.35 | 0.259 | 0.42324137094 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| H/P | 5970 |
Ig-43 |
52 | rs539871760 |
0.6571 | 0.68 | 0.822 | N | 0.35 | 0.259 | 0.42324137094 | gnomAD-4.0.0 | 6.56676E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07297E-04 | 0 |
| H/R | 5970 |
Ig-43 |
52 | rs539871760 |
0.1328 | -0.086 | 0.175 | N | 0.228 | 0.196 | 0.236278675362 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/G | 6063 |
Ig-44 |
52 | None | 0.2096 | None | 0.992 | N | 0.659 | 0.535 | 0.366848117066 | gnomAD-4.0.0 | 1.59195E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43295E-05 | 0 |
| I/T | 6157 |
Ig-45 |
53 | rs371882162 |
0.0587 | -0.389 | None | N | 0.138 | 0.085 | None | gnomAD-2.1.1 | 6.78E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.32844E-04 | 1.40292E-04 |
| I/T | 6157 |
Ig-45 |
53 | rs371882162 |
0.0587 | -0.389 | None | N | 0.138 | 0.085 | None | gnomAD-3.1.2 | 7.89E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.61784E-04 | 0 | 0 |
| I/T | 6157 |
Ig-45 |
53 | rs371882162 |
0.0587 | -0.389 | None | N | 0.138 | 0.085 | None | gnomAD-4.0.0 | 7.87055E-05 | None | None | None | None | N | None | 2.6698E-05 | 3.33433E-05 | None | 0 | 0 | None | 0 | 0 | 1.02566E-04 | 0 | 3.20225E-05 |
| I/V | 6157 |
Ig-45 |
53 | None | 0.0662 | None | None | N | 0.091 | 0.182 | 0.210429274316 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/K | 6250 |
Ig-46 |
52 | rs952849958 |
0.0682 | -0.342 | None | N | 0.135 | 0.15 | 0.159798565429 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| R/K | 6250 |
Ig-46 |
52 | rs952849958 |
0.0682 | -0.342 | None | N | 0.135 | 0.15 | 0.159798565429 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/K | 6250 |
Ig-46 |
52 | rs952849958 |
0.0682 | -0.342 | None | N | 0.135 | 0.15 | 0.159798565429 | gnomAD-4.0.0 | 4.95807E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08616E-06 | 2.19563E-05 | 0 |
| V/A | 6343 |
Ig-47 |
52 | None | 0.0828 | None | None | N | 0.075 | 0.129 | 0.486209434461 | gnomAD-4.0.0 | 1.59318E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86056E-06 | 0 | 0 |
| E/A | 6436 |
Ig-48 |
52 | rs778366508 |
0.2385 | -0.2 | 0.896 | D | 0.434 | 0.283 | 0.413891365518 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 0 | None | 0 | 0 | 0 |
| E/A | 6436 |
Ig-48 |
52 | rs778366508 |
0.2385 | -0.2 | 0.896 | D | 0.434 | 0.283 | 0.413891365518 | gnomAD-4.0.0 | 1.59258E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.78056E-05 | None | 0 | 0 | 0 | 0 | 0 |
| H/L | 6532 |
Ig-49 |
52 | None | 0.1186 | None | 0.351 | N | 0.318 | 0.302 | 0.547341738503 | gnomAD-4.0.0 | 1.59275E-06 | None | None | None | None | I | None | 5.66765E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/N | 6719 |
Ig-51 |
53 | rs770377168 |
0.1367 | None | 0.351 | N | 0.414 | 0.201 | 0.659007425792 | gnomAD-4.0.0 | 2.05334E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52067E-05 | None | 0 | 0 | 1.79945E-06 | 0 | 0 |
| I/T | 6719 |
Ig-51 |
53 | rs770377168 |
0.0619 | -0.224 | 0.003 | N | 0.131 | 0.215 | 0.582860479048 | gnomAD-2.1.1 | 3.93E-05 | None | None | None | None | N | None | 0 | 1.41683E-04 | None | 0 | 0 | None | 0 | None | 0 | 3.13E-05 | 2.8177E-04 |
| I/T | 6719 |
Ig-51 |
53 | rs770377168 |
0.0619 | -0.224 | 0.003 | N | 0.131 | 0.215 | 0.582860479048 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| I/T | 6719 |
Ig-51 |
53 | rs770377168 |
0.0619 | -0.224 | 0.003 | N | 0.131 | 0.215 | 0.582860479048 | gnomAD-4.0.0 | 1.48778E-05 | None | None | None | None | N | None | 1.33565E-05 | 8.34195E-05 | None | 0 | 0 | None | 0 | 0 | 1.27179E-05 | 0 | 4.80507E-05 |
| I/V | 6719 |
Ig-51 |
53 | None | 0.0708 | None | 0.003 | N | 0.135 | 0.075 | 0.411932830014 | gnomAD-4.0.0 | 1.59253E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43373E-05 | 0 |
| V/A | 6906 |
Ig-53 |
53 | rs1560728367 |
0.0862 | None | 0.425 | N | 0.198 | 0.134 | 0.58541340546 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/A | 6906 |
Ig-53 |
53 | rs1560728367 |
0.0862 | None | 0.425 | N | 0.198 | 0.134 | 0.58541340546 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/E | 6906 |
Ig-53 |
53 | None | 0.1211 | None | 0.01 | N | 0.178 | 0.24 | 0.709453217969 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| V/L | 6906 |
Ig-53 |
53 | None | 0.1177 | None | 0.053 | N | 0.205 | 0.14 | 0.442567846599 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Y/C | 6999 |
Ig-54 |
52 | rs1343770232 |
0.0876 | -0.286 | 0.56 | D | 0.215 | 0.236 | 0.442466506703 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| Y/C | 6999 |
Ig-54 |
52 | rs1343770232 |
0.0876 | -0.286 | 0.56 | D | 0.215 | 0.236 | 0.442466506703 | gnomAD-4.0.0 | 6.84326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73671E-04 | 8.09636E-06 | 0 | 0 |
| T/A | 7281 |
Ig-57 |
52 | rs1482166056 |
0.1299 | -0.265 | 0.999 | N | 0.465 | 0.34 | 0.367992661779 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| T/A | 7281 |
Ig-57 |
52 | rs1482166056 |
0.1299 | -0.265 | 0.999 | N | 0.465 | 0.34 | 0.367992661779 | gnomAD-4.0.0 | 2.73727E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.59821E-06 | 0 | 0 |
| T/R | 7281 |
Ig-57 |
52 | rs2078711757 |
0.2576 | None | 1.0 | N | 0.669 | 0.454 | 0.741619954273 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.44E-05 | 0 | 0 | 0 | 0 |
| T/R | 7281 |
Ig-57 |
52 | rs2078711757 |
0.2576 | None | 1.0 | N | 0.669 | 0.454 | 0.741619954273 | gnomAD-4.0.0 | 6.57869E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.43752E-05 | 0 | 0 | 0 | 0 |
| T/A | 7374 |
Ig-58 |
52 | None | 0.0823 | None | 0.01 | N | 0.071 | 0.135 | 0.197625483188 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| T/I | 7374 |
Ig-58 |
52 | rs879022559 |
0.1562 | 0.048 | 0.642 | N | 0.338 | 0.268 | None | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.82E-06 | 0 |
| T/I | 7374 |
Ig-58 |
52 | rs879022559 |
0.1562 | 0.048 | 0.642 | N | 0.338 | 0.268 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 7374 |
Ig-58 |
52 | rs879022559 |
0.1562 | 0.048 | 0.642 | N | 0.338 | 0.268 | None | gnomAD-4.0.0 | 2.47957E-06 | None | None | None | None | N | None | 4.00588E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47778E-07 | 0 | 0 |
| V/A | 7470 |
Ig-59 |
52 | rs1429215263 |
0.1285 | -0.381 | 0.425 | N | 0.219 | 0.14 | 0.568500581595 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.59E-05 | None | 0 | None | 0 | 0 | 0 |
| V/A | 7470 |
Ig-59 |
52 | rs1429215263 |
0.1285 | -0.381 | 0.425 | N | 0.219 | 0.14 | 0.568500581595 | gnomAD-4.0.0 | 1.36874E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.52118E-05 | None | 0 | 0 | 8.99619E-07 | 0 | 0 |
| K/E | 7753 |
Ig-62 |
52 | None | 0.1918 | None | 0.959 | N | 0.311 | 0.269 | 0.30212335484 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 7753 |
Ig-62 |
52 | None | 0.3988 | None | 0.994 | N | 0.321 | 0.239 | 0.287603790349 | gnomAD-4.0.0 | 6.84279E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99549E-07 | 0 | 0 |
| I/T | 7847 |
Ig-63 |
53 | rs2078114605 |
0.0664 | None | None | N | 0.135 | 0.12 | 0.346768085243 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 7847 |
Ig-63 |
53 | rs2078114605 |
0.0664 | None | None | N | 0.135 | 0.12 | 0.346768085243 | gnomAD-4.0.0 | 6.57108E-06 | None | None | None | None | I | None | 2.41196E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 7847 |
Ig-63 |
53 | rs1268176947 |
0.0644 | -0.115 | None | N | 0.091 | 0.194 | 0.158396225186 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 1.65782E-04 |
| I/V | 7847 |
Ig-63 |
53 | rs1268176947 |
0.0644 | -0.115 | None | N | 0.091 | 0.194 | 0.158396225186 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| I/V | 7847 |
Ig-63 |
53 | rs1268176947 |
0.0644 | -0.115 | None | N | 0.091 | 0.194 | 0.158396225186 | gnomAD-4.0.0 | 4.95762E-06 | None | None | None | None | I | None | 1.33469E-05 | 0 | None | 0 | 0 | None | 0 | 1.6442E-04 | 5.08596E-06 | 0 | 0 |
| I/N | 7940 |
Ig-64 |
52 | None | 0.1062 | None | 0.033 | N | 0.427 | 0.131 | 0.461058313273 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 7940 |
Ig-64 |
52 | None | 0.0679 | None | None | N | 0.079 | 0.129 | 0.159798565429 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| S/L | 8036 |
Ig-65 |
52 | rs200598509 |
0.078 | 0.134 | None | N | 0.112 | 0.116 | None | gnomAD-2.1.1 | 7.24E-05 | None | None | None | None | N | None | 0 | 8.69E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.24387E-04 | 1.65618E-04 |
| S/L | 8036 |
Ig-65 |
52 | rs200598509 |
0.078 | 0.134 | None | N | 0.112 | 0.116 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 8.82E-05 | 0 | 0 |
| S/L | 8036 |
Ig-65 |
52 | rs200598509 |
0.078 | 0.134 | None | N | 0.112 | 0.116 | None | gnomAD-4.0.0 | 5.82499E-05 | None | None | None | None | N | None | 3.99979E-05 | 4.9995E-05 | None | 0 | 0 | None | 0 | 3.9604E-03 | 5.08583E-05 | 2.19592E-05 | 3.20113E-05 |
| T/I | 8222 |
Ig-67 |
52 | None | 0.7969 | None | 0.994 | D | 0.322 | 0.357 | 0.482283251092 | gnomAD-4.0.0 | 6.84228E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99496E-07 | 0 | 0 |
| T/R | 8222 |
Ig-67 |
52 | None | 0.5133 | None | 0.994 | D | 0.324 | 0.336 | 0.532842626647 | gnomAD-4.0.0 | 6.84228E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99496E-07 | 0 | 0 |
| V/I | 8411 |
Ig-69 |
52 | rs760523669 |
0.0656 | -0.057 | 0.001 | N | 0.124 | 0.039 | 0.417334834585 | gnomAD-2.1.1 | 6.06E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 6.51951E-04 | 8.93E-06 | 0 |
| V/I | 8411 |
Ig-69 |
52 | rs760523669 |
0.0656 | -0.057 | 0.001 | N | 0.124 | 0.039 | 0.417334834585 | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 6.59631E-04 | 0 | 0 | 0 | 4.78011E-04 |
| V/I | 8411 |
Ig-69 |
52 | rs760523669 |
0.0656 | -0.057 | 0.001 | N | 0.124 | 0.039 | 0.417334834585 | gnomAD-4.0.0 | 4.21531E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.69131E-04 | 0 | 2.96723E-05 | 0 | 4.80584E-05 |
| V/I | 8507 |
Ig-70 |
52 | None | 0.0787 | None | None | N | 0.222 | 0.136 | 0.517322629239 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/F | 8601 |
Ig-71 |
53 | rs184812963 |
0.128 | -0.396 | 0.069 | N | 0.372 | 0.113 | None | gnomAD-2.1.1 | 5E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 7.1817E-04 | None | 0 | None | 0 | 0 | 0 |
| V/F | 8601 |
Ig-71 |
53 | rs184812963 |
0.128 | -0.396 | 0.069 | N | 0.372 | 0.113 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | I | None | 0 | 6.55E-05 | 0 | 0 | 3.8625E-04 | None | 0 | 0 | 0 | 0 | 0 |
| V/F | 8601 |
Ig-71 |
53 | rs184812963 |
0.128 | -0.396 | 0.069 | N | 0.372 | 0.113 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | I | None | 0 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| V/F | 8601 |
Ig-71 |
53 | rs184812963 |
0.128 | -0.396 | 0.069 | N | 0.372 | 0.113 | None | gnomAD-4.0.0 | 1.42535E-05 | None | None | None | None | I | None | 0 | 1.66689E-05 | None | 0 | 4.68227E-04 | None | 0 | 0 | 0 | 0 | 1.60087E-05 |
| V/I | 8601 |
Ig-71 |
53 | rs184812963 |
0.0675 | 0.196 | None | N | 0.181 | 0.116 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/I | 8601 |
Ig-71 |
53 | rs184812963 |
0.0675 | 0.196 | None | N | 0.181 | 0.116 | None | gnomAD-4.0.0 | 5.47425E-06 | None | None | None | None | I | None | 0 | 0 | None | 3.82702E-05 | 5.03981E-05 | None | 1.87322E-05 | 0 | 1.79911E-06 | 1.15942E-05 | 1.65689E-05 |
| E/Q | 8694 |
Ig-72 |
52 | rs373247663 |
0.1614 | 0.382 | 0.135 | N | 0.207 | 0.149 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| F/L | 8881 |
Ig-74 |
52 | rs982955034 |
0.5836 | -0.463 | 0.828 | N | 0.251 | 0.188 | 0.386395597597 | gnomAD-2.1.1 | 7.14E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.67E-05 | 0 | None | 0 | None | 0 | 7.81E-06 | 0 |
| F/L | 8881 |
Ig-74 |
52 | rs982955034 |
0.5836 | -0.463 | 0.828 | N | 0.251 | 0.188 | 0.386395597597 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 5.76369E-04 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| F/L | 8881 |
Ig-74 |
52 | rs982955034 |
0.5836 | -0.463 | 0.828 | N | 0.251 | 0.188 | 0.386395597597 | gnomAD-4.0.0 | 5.57812E-06 | None | None | None | None | N | None | 0 | 0 | None | 2.02744E-04 | 0 | None | 0 | 0 | 8.4769E-07 | 0 | 3.20328E-05 |
| F/S | 8881 |
Ig-74 |
52 | None | 0.2035 | None | 0.276 | N | 0.157 | 0.191 | 0.596902567841 | gnomAD-4.0.0 | 1.59173E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02627E-05 |
| F/V | 8881 |
Ig-74 |
52 | rs1174332291 |
0.1299 | None | 0.238 | N | 0.217 | 0.17 | 0.505701759113 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| F/V | 8881 |
Ig-74 |
52 | rs1174332291 |
0.1299 | None | 0.238 | N | 0.217 | 0.17 | 0.505701759113 | gnomAD-4.0.0 | 9.9166E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.35626E-05 | 0 | 0 |
| T/K | 8977 |
Ig-75 |
52 | None | 0.2121 | None | 0.92 | N | 0.246 | 0.263 | 0.371344866733 | gnomAD-4.0.0 | 1.59163E-06 | None | None | None | None | N | None | 0 | 2.28781E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 9070 |
Ig-76 |
52 | rs1226337905 |
0.1265 | None | None | N | 0.093 | 0.099 | 0.143124449307 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/D | 9070 |
Ig-76 |
52 | rs1226337905 |
0.1265 | None | None | N | 0.093 | 0.099 | 0.143124449307 | gnomAD-4.0.0 | 6.57246E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47003E-05 | 0 | 0 |
| R/S | 9256 |
Ig-78 |
52 | None | 0.2695 | None | 0.001 | N | 0.154 | 0.136 | 0.203808441222 | gnomAD-4.0.0 | 1.59129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85835E-06 | 0 | 0 |
| L/S | 9352 |
Ig-79 |
52 | rs776487201 |
0.1153 | -0.046 | 0.801 | None | 0.295 | 0.172 | 0.781844667515 | gnomAD-2.1.1 | 1.40515E-04 | None | None | None | None | N | None | 0 | 9.84879E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65344E-04 |
| L/S | 9352 |
Ig-79 |
52 | rs776487201 |
0.1153 | -0.046 | 0.801 | None | 0.295 | 0.172 | 0.781844667515 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/S | 9352 |
Ig-79 |
52 | rs776487201 |
0.1153 | -0.046 | 0.801 | None | 0.295 | 0.172 | 0.781844667515 | gnomAD-4.0.0 | 2.41676E-05 | None | None | None | None | N | None | 0 | 6.16852E-04 | None | 0 | 0 | None | 0 | 0 | 8.47597E-07 | 0 | 1.60082E-05 |
| K/N | 9750 |
Ig-83 |
53 | None | 0.6044 | None | 0.993 | None | 0.616 | 0.273 | 0.261217442401 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/H | 9952 |
Ig-84 |
53 | rs773555150 |
0.1377 | 0.43 | 0.602 | None | 0.263 | 0.126 | None | gnomAD-2.1.1 | 8.12E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| D/H | 9952 |
Ig-84 |
53 | rs773555150 |
0.1377 | 0.43 | 0.602 | None | 0.263 | 0.126 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 4.78469E-04 |
| D/H | 9952 |
Ig-84 |
53 | rs773555150 |
0.1377 | 0.43 | 0.602 | None | 0.263 | 0.126 | None | gnomAD-4.0.0 | 9.92195E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18728E-05 | 0 | 3.2042E-05 |
| E/K | 10039 |
Ig-85 |
51 | None | 0.2527 | None | 0.003 | None | 0.113 | 0.188 | 0.265929055128 | gnomAD-4.0.0 | 1.36828E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79879E-06 | 0 | 0 |
| D/Y | 10128 |
Ig-86 |
51 | None | 0.7981 | None | 0.997 | None | 0.585 | 0.363 | 0.792777554351 | gnomAD-4.0.0 | 1.36826E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79878E-06 | 0 | 0 |
| I/T | 13831 |
Ig-88 |
52 | rs2154230322 |
0.3099 | None | 1.0 | N | 0.56 | 0.44 | 0.739142977588 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| I/V | 13831 |
Ig-88 |
52 | rs1223688724 |
0.1759 | None | 0.993 | N | 0.347 | 0.283 | 0.547384771329 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/G | 13926 |
Ig-89 |
51 | None | 0.3454 | None | 0.189 | N | 0.51 | 0.27 | 0.188950314367 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| D/N | 13926 |
Ig-89 |
51 | rs2060332594 |
0.1606 | None | 0.449 | N | 0.558 | 0.247 | 0.195762928549 | gnomAD-4.0.0 | 2.56338E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.35837E-05 | 0 | 0 |
| E/K | 14015 |
Ig-90 |
51 | rs2060226377 |
0.3852 | None | 0.297 | N | 0.539 | 0.157 | None | gnomAD-4.0.0 | 1.59968E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86609E-06 | 0 | 0 |
| E/V | 14015 |
Ig-90 |
51 | None | 0.3044 | None | 0.857 | N | 0.648 | 0.276 | None | gnomAD-4.0.0 | 1.59987E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86618E-06 | 0 | 0 |
| D/N | 14103 |
Ig-91 |
50 | None | 0.4219 | None | 1.0 | D | 0.604 | 0.419 | 0.492200611407 | gnomAD-4.0.0 | 1.59233E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86017E-06 | 0 | 0 |
| D/V | 14103 |
Ig-91 |
50 | rs775487599 |
0.7418 | 0.298 | 1.0 | D | 0.746 | 0.57 | 0.724769792947 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| D/V | 14103 |
Ig-91 |
50 | rs775487599 |
0.7418 | 0.298 | 1.0 | D | 0.746 | 0.57 | 0.724769792947 | gnomAD-4.0.0 | 3.18463E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72027E-06 | 0 | 0 |
| D/E | 14280 |
Ig-93 |
50 | rs760643071 |
0.1473 | 0.046 | 0.014 | N | 0.183 | 0.098 | 0.0762999501168 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| D/E | 14280 |
Ig-93 |
50 | rs760643071 |
0.1473 | 0.046 | 0.014 | N | 0.183 | 0.098 | 0.0762999501168 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| D/E | 14280 |
Ig-93 |
50 | rs760643071 |
0.1473 | 0.046 | 0.014 | N | 0.183 | 0.098 | 0.0762999501168 | gnomAD-4.0.0 | 1.59217E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85948E-06 | 0 | 0 |
| D/G | 14280 |
Ig-93 |
50 | rs181902304 |
0.2642 | -0.409 | 0.698 | D | 0.371 | 0.424 | None | gnomAD-2.1.1 | 9.29E-05 | None | None | None | None | N | None | 4.13E-05 | 2.83094E-04 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 1.09539E-04 | 0 |
| D/G | 14280 |
Ig-93 |
50 | rs181902304 |
0.2642 | -0.409 | 0.698 | D | 0.371 | 0.424 | None | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47059E-04 | 0 | 0 |
| D/G | 14280 |
Ig-93 |
50 | rs181902304 |
0.2642 | -0.409 | 0.698 | D | 0.371 | 0.424 | None | gnomAD-4.0.0 | 5.45471E-05 | None | None | None | None | N | None | 1.33522E-05 | 1.66789E-04 | None | 0 | 0 | None | 0 | 0 | 6.27327E-05 | 2.19587E-05 | 1.60174E-05 |
| D/V | 14280 |
Ig-93 |
50 | rs181902304 |
0.2078 | 0.315 | 0.89 | D | 0.617 | 0.46 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93199E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 14280 |
Ig-93 |
50 | rs181902304 |
0.2078 | 0.315 | 0.89 | D | 0.617 | 0.46 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| D/V | 14280 |
Ig-93 |
50 | rs181902304 |
0.2078 | 0.315 | 0.89 | D | 0.617 | 0.46 | None | gnomAD-4.0.0 | 6.56892E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.93648E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 14458 |
Ig-95 |
51 | None | 0.1248 | None | 0.006 | N | 0.218 | 0.264 | 0.376216005999 | gnomAD-4.0.0 | 5.47445E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19673E-06 | 0 | 0 |
| E/K | 14547 |
Ig-96 |
51 | rs761539202 |
0.0942 | 1.041 | 0.426 | D | 0.4 | 0.392 | 0.407082143382 | gnomAD-2.1.1 | 7.35E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.61E-05 | 0 |
| E/K | 14547 |
Ig-96 |
51 | rs761539202 |
0.0942 | 1.041 | 0.426 | D | 0.4 | 0.392 | 0.407082143382 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| E/K | 14547 |
Ig-96 |
51 | rs761539202 |
0.0942 | 1.041 | 0.426 | D | 0.4 | 0.392 | 0.407082143382 | gnomAD-4.0.0 | 1.30534E-05 | None | None | None | None | N | None | 1.33668E-05 | 0 | None | 3.40044E-05 | 0 | None | 0 | 0 | 1.44376E-05 | 0 | 3.21192E-05 |
| E/Q | 14547 |
Ig-96 |
51 | rs761539202 |
0.1359 | 0.854 | 0.405 | D | 0.381 | 0.361 | 0.457197642564 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.18E-06 | 0 |
| E/Q | 14547 |
Ig-96 |
51 | rs761539202 |
0.1359 | 0.854 | 0.405 | D | 0.381 | 0.361 | 0.457197642564 | gnomAD-4.0.0 | 6.86468E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.01315E-07 | 0 | 0 |
| D/E | 14636 |
Ig-97 |
51 | rs1469705451 |
0.2128 | 0.104 | 0.767 | N | 0.274 | 0.101 | 0.393159880135 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.24643E-04 | None | 0 | None | 0 | 0 | 0 |
| D/E | 14636 |
Ig-97 |
51 | rs1469705451 |
0.2128 | 0.104 | 0.767 | N | 0.274 | 0.101 | 0.393159880135 | gnomAD-4.0.0 | 6.36916E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11297E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 14636 |
Ig-97 |
51 | None | 0.3985 | None | 1.0 | D | 0.684 | 0.508 | 0.577797438266 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.21507E-04 | 0 |
| E/G | 14725 |
Ig-98 |
51 | None | 0.1988 | None | 0.999 | N | 0.643 | 0.394 | 0.309530620856 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/D | 14814 |
Ig-99 |
50 | None | 0.1317 | None | None | N | 0.174 | 0.05 | 0.288727942641 | gnomAD-4.0.0 | 6.99536E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.09182E-07 | 0 | 0 |
| D/Y | 14903 |
Ig-100 |
51 | None | 0.3268 | None | 1.0 | D | 0.74 | 0.456 | 0.75049894695 | gnomAD-4.0.0 | 1.59344E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.4332E-05 | 0 |
| K/E | 14992 |
Ig-101 |
51 | rs1174482047 |
0.1914 | 0.465 | 0.134 | N | 0.194 | 0.156 | 0.237489013734 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.89257E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 14992 |
Ig-101 |
51 | rs1174482047 |
0.1914 | 0.465 | 0.134 | N | 0.194 | 0.156 | 0.237489013734 | gnomAD-4.0.0 | 1.31617E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 3.89257E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 14992 |
Ig-101 |
51 | rs2058355200 |
0.5071 | None | 0.959 | N | 0.386 | 0.272 | 0.291694819147 | gnomAD-4.0.0 | 1.59602E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86546E-06 | 0 | 0 |
| K/Q | 14992 |
Ig-101 |
51 | rs1174482047 |
0.172 | 0.201 | 0.31 | N | 0.192 | 0.153 | 0.242825505644 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 14992 |
Ig-101 |
51 | rs1174482047 |
0.172 | 0.201 | 0.31 | N | 0.192 | 0.153 | 0.242825505644 | gnomAD-4.0.0 | 1.59614E-06 | None | None | None | None | N | None | 0 | 2.2979E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 15170 |
Ig-103 |
51 | None | 0.1682 | None | 0.37 | N | 0.259 | 0.105 | 0.291694819147 | gnomAD-4.0.0 | 1.36937E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99819E-07 | 0 | 1.6587E-05 |
| D/N | 15170 |
Ig-103 |
51 | rs751407435 |
0.118 | 0.454 | 0.997 | D | 0.439 | 0.389 | None | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| D/N | 15170 |
Ig-103 |
51 | rs751407435 |
0.118 | 0.454 | 0.997 | D | 0.439 | 0.389 | None | gnomAD-4.0.0 | 1.30101E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.61979E-05 | 0 | 1.65909E-05 |
| D/G | 15352 |
Ig-105 |
51 | rs769556979 |
0.4448 | -0.66 | 1.0 | D | 0.659 | 0.564 | 0.43046518545 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.58E-05 | 0 |
| D/G | 15352 |
Ig-105 |
51 | rs769556979 |
0.4448 | -0.66 | 1.0 | D | 0.659 | 0.564 | 0.43046518545 | gnomAD-4.0.0 | 7.97123E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.43201E-05 | 0 | 0 |
| T/A | 15616 |
Ig-108 |
49 | rs794727331 |
0.0819 | None | 0.835 | N | 0.331 | 0.21 | 0.3691244813 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 15616 |
Ig-108 |
49 | rs794727331 |
0.0819 | None | 0.835 | N | 0.331 | 0.21 | 0.3691244813 | gnomAD-4.0.0 | 1.11655E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52678E-05 | 0 | 0 |
| T/M | 15616 |
Ig-108 |
49 | rs368057764 |
0.1076 | 0.058 | 1.0 | N | 0.545 | 0.446 | 0.576013683475 | gnomAD-2.1.1 | 2.15173E-04 | None | None | None | None | N | None | 4.14E-05 | 2.84E-05 | None | 0 | 1.45349E-03 | None | 7.84929E-04 | None | 4.01E-05 | 3.14E-05 | 1.41243E-04 |
| T/M | 15616 |
Ig-108 |
49 | rs368057764 |
0.1076 | 0.058 | 1.0 | N | 0.545 | 0.446 | 0.576013683475 | gnomAD-3.1.2 | 1.11969E-04 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 1.16731E-03 | None | 0 | 0 | 2.95E-05 | 1.65632E-03 | 0 |
| T/M | 15616 |
Ig-108 |
49 | rs368057764 |
0.1076 | 0.058 | 1.0 | N | 0.545 | 0.446 | 0.576013683475 | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 2E-03 | None |
| T/M | 15616 |
Ig-108 |
49 | rs368057764 |
0.1076 | 0.058 | 1.0 | N | 0.545 | 0.446 | 0.576013683475 | gnomAD-4.0.0 | 9.67704E-05 | None | None | None | None | N | None | 1.33551E-05 | 3.34314E-05 | None | 0 | 6.04622E-04 | None | 4.69381E-05 | 0 | 3.13851E-05 | 7.25147E-04 | 3.20626E-04 |
| T/R | 15616 |
Ig-108 |
49 | rs368057764 |
0.1677 | None | 0.998 | N | 0.54 | 0.482 | 0.559961094632 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/R | 15616 |
Ig-108 |
49 | rs368057764 |
0.1677 | None | 0.998 | N | 0.54 | 0.482 | 0.559961094632 | gnomAD-4.0.0 | 6.5864E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47327E-05 | 0 | 0 |
| L/S | 16014 |
Ig-109 |
47 | None | 0.0941 | None | None | N | 0.183 | 0.137 | 0.634102980643 | gnomAD-4.0.0 | 7.20193E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.87501E-06 | 0 | 0 |
| V/I | 16310 |
Ig-110 |
49 | rs1401698279 |
0.0699 | -0.156 | 0.002 | N | 0.175 | 0.065 | 0.407632638399 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.66778E-04 |
| V/I | 16310 |
Ig-110 |
49 | rs1401698279 |
0.0699 | -0.156 | 0.002 | N | 0.175 | 0.065 | 0.407632638399 | gnomAD-4.0.0 | 1.59407E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.03104E-05 |
| D/V | 17006 |
Ig-111 |
52 | None | 0.3065 | None | 0.942 | N | 0.643 | 0.408 | 0.653256221078 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/Q | 17328 |
Ig-112 |
78 | rs371827403 |
0.1047 | 0.18 | None | N | 0.193 | 0.087 | None | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 17328 |
Ig-112 |
78 | rs371827403 |
0.1047 | 0.18 | None | N | 0.193 | 0.087 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 17328 |
Ig-112 |
78 | rs371827403 |
0.1047 | 0.18 | None | N | 0.193 | 0.087 | None | gnomAD-4.0.0 | 2.57267E-06 | None | None | None | None | N | None | 1.69779E-05 | 0 | None | 0 | 2.44093E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 17328 |
Ig-112 |
78 | rs1268313785 |
0.0718 | None | None | N | 0.243 | 0.03 | 0.18274738541 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 17328 |
Ig-112 |
78 | rs1268313785 |
0.0718 | None | None | N | 0.243 | 0.03 | 0.18274738541 | gnomAD-4.0.0 | 2.03033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20509E-06 | 0 | 3.40321E-05 |
| V/A | 17723 |
Ig-113 |
47 | rs1420844949 |
0.1144 | None | 0.061 | N | 0.135 | 0.123 | 0.413241256734 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 17723 |
Ig-113 |
47 | rs1420844949 |
0.1144 | None | 0.061 | N | 0.135 | 0.123 | 0.413241256734 | gnomAD-4.0.0 | 5.57955E-06 | None | None | None | None | I | None | 0 | 1.66756E-05 | None | 0 | 0 | None | 0 | 0 | 6.78333E-06 | 0 | 0 |
| V/D | 17723 |
Ig-113 |
47 | rs1420844949 |
0.1989 | 0.128 | 0.852 | N | 0.333 | 0.325 | 0.700328372174 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/D | 17723 |
Ig-113 |
47 | rs1420844949 |
0.1989 | 0.128 | 0.852 | N | 0.333 | 0.325 | 0.700328372174 | gnomAD-4.0.0 | 1.3688E-06 | None | None | None | None | I | None | 2.99133E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15955E-05 | 0 |
| V/I | 17723 |
Ig-113 |
47 | rs2055183327 |
0.08 | None | 0.964 | N | 0.227 | 0.178 | 0.563544018958 | gnomAD-4.0.0 | 4.10644E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.87266E-05 | 0 | 1.79946E-06 | 1.15955E-05 | 3.31521E-05 |
| V/L | 17723 |
Ig-113 |
47 | None | 0.2031 | None | 0.924 | N | 0.273 | 0.213 | 0.456462010053 | gnomAD-4.0.0 | 6.84406E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99729E-07 | 0 | 0 |
| S/G | 18024 |
Ig-114 |
57 | None | 0.15 | None | 0.024 | N | 0.453 | 0.085 | 0.124217242631 | gnomAD-4.0.0 | 1.59334E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86229E-06 | 0 | 0 |
| A/T | 18438 |
Ig-115 |
57 | rs1416049620 |
0.0646 | None | 0.007 | N | 0.142 | 0.135 | 0.195762928549 | gnomAD-4.0.0 | 1.62326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.50267E-05 | 0 |
| V/A | 18743 |
Ig-116 |
56 | rs1458979908 |
0.0856 | -0.729 | None | N | 0.128 | 0.142 | 0.258283824007 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| V/A | 18743 |
Ig-116 |
56 | rs1458979908 |
0.0856 | -0.729 | None | N | 0.128 | 0.142 | 0.258283824007 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/A | 18743 |
Ig-116 |
56 | rs1458979908 |
0.0856 | -0.729 | None | N | 0.128 | 0.142 | 0.258283824007 | gnomAD-4.0.0 | 6.5754E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47093E-05 | 0 | 0 |
| V/I | 18743 |
Ig-116 |
56 | rs1412927935 |
0.0737 | -0.297 | 0.116 | N | 0.275 | 0.171 | 0.347879110917 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | I | None | 0 | 8.71E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/I | 18743 |
Ig-116 |
56 | rs1412927935 |
0.0737 | -0.297 | 0.116 | N | 0.275 | 0.171 | 0.347879110917 | gnomAD-4.0.0 | 4.77864E-06 | None | None | None | None | I | None | 0 | 6.86342E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 19142 |
Ig-117 |
48 | None | 0.3743 | None | 0.117 | N | 0.281 | 0.229 | 0.258779203287 | gnomAD-4.0.0 | 1.59268E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86E-06 | 0 | 0 |
| T/I | 19142 |
Ig-117 |
48 | rs1576218735 |
0.9024 | None | 0.993 | D | 0.613 | 0.433 | 0.731554227051 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94326E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 19142 |
Ig-117 |
48 | rs1576218735 |
0.9024 | None | 0.993 | D | 0.613 | 0.433 | 0.731554227051 | gnomAD-4.0.0 | 2.03011E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.13947E-04 | None | 0 | 0 | 1.20498E-06 | 0 | 0 |
| T/P | 19142 |
Ig-117 |
48 | rs760195565 |
0.7912 | -0.481 | 0.997 | N | 0.61 | 0.533 | None | gnomAD-4.0.0 | 6.37075E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 7.54888E-05 | 0 | 0 | 0 | 0 |
| T/I | 19438 |
Ig-118 |
48 | rs182907667 |
0.3442 | None | 0.971 | N | 0.557 | 0.387 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.94024E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 19438 |
Ig-118 |
48 | rs182907667 |
0.3442 | None | 0.971 | N | 0.557 | 0.387 | None | gnomAD-4.0.0 | 6.57212E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.94477E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 20130 |
Ig-120 |
51 | rs2050148296 |
0.2814 | None | 0.999 | N | 0.395 | 0.303 | 0.385906861911 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 20130 |
Ig-120 |
51 | rs2050148296 |
0.2814 | None | 0.999 | N | 0.395 | 0.303 | 0.385906861911 | gnomAD-4.0.0 | 6.57696E-06 | None | None | None | None | N | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 20130 |
Ig-120 |
51 | rs772986855 |
0.4936 | -0.473 | 1.0 | N | 0.649 | 0.425 | 0.455173453901 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| D/H | 20130 |
Ig-120 |
51 | rs772986855 |
0.4936 | -0.473 | 1.0 | N | 0.649 | 0.425 | 0.455173453901 | gnomAD-4.0.0 | 3.18439E-06 | None | None | None | None | N | None | 0 | 4.57352E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 20528 |
Ig-121 |
50 | rs374601610 |
0.1189 | -0.161 | None | N | 0.177 | 0.116 | 0.0884992946249 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| D/E | 20528 |
Ig-121 |
50 | rs374601610 |
0.1189 | -0.161 | None | N | 0.177 | 0.116 | 0.0884992946249 | gnomAD-4.0.0 | 6.84431E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99672E-07 | 0 | 0 |
| R/C | 20823 |
Ig-122 |
55 | rs779686013 |
0.0988 | -0.111 | 0.032 | D | 0.41 | 0.077 | 0.367042808489 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| R/C | 20823 |
Ig-122 |
55 | rs779686013 |
0.0988 | -0.111 | 0.032 | D | 0.41 | 0.077 | 0.367042808489 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 20823 |
Ig-122 |
55 | rs779686013 |
0.0988 | -0.111 | 0.032 | D | 0.41 | 0.077 | 0.367042808489 | gnomAD-4.0.0 | 8.05786E-06 | None | None | None | None | N | None | 2.67065E-05 | 1.66795E-05 | None | 0 | 0 | None | 0 | 0 | 8.47732E-06 | 0 | 0 |
| R/H | 20823 |
Ig-122 |
55 | rs758019778 |
0.0715 | -0.719 | 0.014 | N | 0.283 | 0.074 | 0.300110245524 | gnomAD-2.1.1 | 5.23E-05 | None | None | None | None | N | None | 6.46E-05 | 5.8E-05 | None | 0 | 0 | None | 2.28833E-04 | None | 0 | 2.66E-05 | 0 |
| R/H | 20823 |
Ig-122 |
55 | rs758019778 |
0.0715 | -0.719 | 0.014 | N | 0.283 | 0.074 | 0.300110245524 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.41E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| R/H | 20823 |
Ig-122 |
55 | rs758019778 |
0.0715 | -0.719 | 0.014 | N | 0.283 | 0.074 | 0.300110245524 | gnomAD-4.0.0 | 2.85121E-05 | None | None | None | None | N | None | 1.33497E-05 | 6.67267E-05 | None | 3.37998E-05 | 0 | None | 0 | 0 | 1.61068E-05 | 2.08617E-04 | 3.20297E-05 |
| V/A | 21225 |
Ig-123 |
49 | rs1396646735 |
0.337 | -0.52 | 0.822 | N | 0.384 | 0.28 | 0.607687067698 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.67E-05 | 0 | 0 |
| V/A | 21225 |
Ig-123 |
49 | rs1396646735 |
0.337 | -0.52 | 0.822 | N | 0.384 | 0.28 | 0.607687067698 | gnomAD-4.0.0 | 4.10775E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.87829E-05 | 0 | 4.49865E-06 | 0 | 0 |
| V/I | 21225 |
Ig-123 |
49 | rs777568221 |
0.1044 | -0.103 | 0.058 | N | 0.224 | 0.123 | 0.346315397577 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | I | None | 0 | 2.91E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/I | 21225 |
Ig-123 |
49 | rs777568221 |
0.1044 | -0.103 | 0.058 | N | 0.224 | 0.123 | 0.346315397577 | gnomAD-4.0.0 | 3.18719E-06 | None | None | None | None | I | None | 0 | 2.28938E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43349E-05 | 0 |
| A/P | 21518 |
Ig-124 |
50 | None | 0.4881 | None | 0.484 | N | 0.271 | 0.224 | 0.36355261348 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/K | 21915 |
Ig-125 |
50 | rs62618736 |
0.054 | 0.456 | None | N | 0.097 | 0.141 | None | gnomAD-2.1.1 | 4.62407E-03 | None | None | None | None | N | None | 4.95868E-02 | 1.68822E-03 | None | 0 | 0 | None | 1.97811E-04 | None | 0 | 1.11115E-04 | 1.56472E-03 |
| Q/K | 21915 |
Ig-125 |
50 | rs62618736 |
0.054 | 0.456 | None | N | 0.097 | 0.141 | None | gnomAD-3.1.2 | 1.38779E-02 | None | None | None | None | N | None | 4.87298E-02 | 4.06131E-03 | 0 | 0 | 1.93798E-04 | None | 0 | 3.16456E-03 | 1.47124E-04 | 2.07211E-04 | 8.12619E-03 |
| Q/K | 21915 |
Ig-125 |
50 | rs62618736 |
0.054 | 0.456 | None | N | 0.097 | 0.141 | None | 1000 genomes | 1.59744E-02 | None | None | None | None | N | None | 5.75E-02 | 5.8E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| Q/K | 21915 |
Ig-125 |
50 | rs62618736 |
0.054 | 0.456 | None | N | 0.097 | 0.141 | None | gnomAD-4.0.0 | 2.70174E-03 | None | None | None | None | N | None | 5.11277E-02 | 2.27501E-03 | None | 0 | 2.24709E-05 | None | 0 | 1.98282E-03 | 1.24743E-04 | 1.65242E-04 | 3.38347E-03 |
| Q/R | 21915 |
Ig-125 |
50 | rs758259657 |
0.0808 | 0.578 | 0.003 | N | 0.159 | 0.139 | 0.228597637076 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| Q/R | 21915 |
Ig-125 |
50 | rs758259657 |
0.0808 | 0.578 | 0.003 | N | 0.159 | 0.139 | 0.228597637076 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 21915 |
Ig-125 |
50 | rs758259657 |
0.0808 | 0.578 | 0.003 | N | 0.159 | 0.139 | 0.228597637076 | gnomAD-4.0.0 | 2.56974E-06 | None | None | None | None | N | None | 0 | 1.70074E-05 | None | 0 | 0 | None | 0 | 0 | 2.39983E-06 | 0 | 0 |
| T/A | 22313 |
Ig-126 |
49 | rs761874347 |
0.271 | -0.684 | 0.948 | D | 0.397 | 0.255 | 0.307648195649 | gnomAD-2.1.1 | 2.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.54E-05 | None | 0 | 2.67E-05 | 0 |
| T/A | 22313 |
Ig-126 |
49 | rs761874347 |
0.271 | -0.684 | 0.948 | D | 0.397 | 0.255 | 0.307648195649 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 22313 |
Ig-126 |
49 | rs761874347 |
0.271 | -0.684 | 0.948 | D | 0.397 | 0.255 | 0.307648195649 | gnomAD-4.0.0 | 1.02558E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.19734E-05 | 2.68097E-05 | 2.84706E-05 |
| T/P | 22313 |
Ig-126 |
49 | rs761874347 |
0.7806 | None | 0.998 | D | 0.575 | 0.523 | 0.447410926215 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 22313 |
Ig-126 |
49 | rs761874347 |
0.7806 | None | 0.998 | D | 0.575 | 0.523 | 0.447410926215 | gnomAD-4.0.0 | 6.57436E-06 | None | None | None | None | N | None | 2.41185E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 22313 |
Ig-126 |
49 | rs2047437261 |
0.1346 | None | 0.775 | N | 0.236 | 0.156 | 0.227934060464 | gnomAD-4.0.0 | 1.59248E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86036E-06 | 0 | 0 |
| S/C | 22602 |
Ig-127 |
43 | None | 0.2142 | None | 0.883 | N | 0.413 | 0.415 | 0.524480850804 | gnomAD-4.0.0 | 8.40227E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.25325E-04 | 0 |
| S/F | 22602 |
Ig-127 |
43 | None | 0.5015 | None | 0.667 | N | 0.467 | 0.436 | 0.674675629537 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| S/P | 22602 |
Ig-127 |
43 | rs780276317 |
0.7995 | None | 0.667 | N | 0.336 | 0.21 | 0.258283824007 | gnomAD-4.0.0 | 1.59188E-06 | None | None | None | None | N | None | 5.66316E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 22999 |
Ig-128 |
50 | rs755306597 |
0.3314 | -0.178 | 0.984 | D | 0.485 | 0.31 | 0.535202146198 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| T/I | 22999 |
Ig-128 |
50 | rs755306597 |
0.3314 | -0.178 | 0.984 | D | 0.485 | 0.31 | 0.535202146198 | gnomAD-4.0.0 | 1.57403E-05 | None | None | None | None | N | None | 0 | 6.70961E-05 | None | 0 | 0 | None | 0 | 0 | 1.79921E-05 | 0 | 0 |
| T/A | 23394 |
Ig-129 |
50 | None | 0.4236 | None | 0.999 | N | 0.469 | 0.549 | 0.441740949975 | gnomAD-4.0.0 | 1.59623E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87167E-06 | 0 | 0 |
| T/M | 23394 |
Ig-129 |
50 | rs397517683 |
0.3549 | -0.016 | 1.0 | N | 0.651 | 0.499 | 0.661236301376 | gnomAD-2.1.1 | 2.41E-05 | None | None | None | None | N | None | 0 | 8.7E-05 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 1.78E-05 | 0 |
| T/M | 23394 |
Ig-129 |
50 | rs397517683 |
0.3549 | -0.016 | 1.0 | N | 0.651 | 0.499 | 0.661236301376 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93949E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/M | 23394 |
Ig-129 |
50 | rs397517683 |
0.3549 | -0.016 | 1.0 | N | 0.651 | 0.499 | 0.661236301376 | gnomAD-4.0.0 | 3.16485E-05 | None | None | None | None | N | None | 0 | 5.00517E-05 | None | 0 | 6.69822E-05 | None | 0 | 0 | 3.73517E-05 | 1.09873E-05 | 0 |
| A/P | 24081 |
Ig-131 |
53 | None | 0.5976 | None | 0.966 | N | 0.336 | 0.26 | 0.483596354421 | gnomAD-4.0.0 | 1.5978E-06 | None | None | None | None | N | None | 0 | 2.29368E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 24081 |
Ig-131 |
53 | rs771966894 |
0.1417 | -0.08 | 0.669 | N | 0.322 | 0.245 | 0.396345573744 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.28E-05 | None | 0 | 0 | 0 |
| A/V | 24081 |
Ig-131 |
53 | rs771966894 |
0.1417 | -0.08 | 0.669 | N | 0.322 | 0.245 | 0.396345573744 | gnomAD-4.0.0 | 1.59754E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43488E-05 | 0 |
| T/I | 24478 |
Ig-132 |
48 | None | 0.8095 | None | 0.976 | N | 0.517 | 0.491 | 0.674603152142 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| T/A | 24767 |
Ig-133 |
52 | None | 0.0948 | None | 0.058 | D | 0.228 | 0.115 | 0.168933306366 | gnomAD-4.0.0 | 1.5917E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8593E-06 | 0 | 0 |
| T/A | 25163 |
Ig-134 |
53 | rs879020274 |
0.1217 | -0.535 | 0.273 | D | 0.365 | 0.235 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.13E-05 | 0 |
| T/A | 25163 |
Ig-134 |
53 | rs879020274 |
0.1217 | -0.535 | 0.273 | D | 0.365 | 0.235 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| T/A | 25163 |
Ig-134 |
53 | rs879020274 |
0.1217 | -0.535 | 0.273 | D | 0.365 | 0.235 | None | gnomAD-4.0.0 | 2.78914E-05 | None | None | None | None | N | None | 1.33526E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.73E-05 | 0 | 0 |
| T/I | 25163 |
Ig-134 |
53 | rs765157072 |
0.4422 | -0.23 | 0.761 | D | 0.377 | 0.36 | 0.527251791467 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/I | 25163 |
Ig-134 |
53 | rs765157072 |
0.4422 | -0.23 | 0.761 | D | 0.377 | 0.36 | 0.527251791467 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 25163 |
Ig-134 |
53 | rs765157072 |
0.4422 | -0.23 | 0.761 | D | 0.377 | 0.36 | 0.527251791467 | gnomAD-4.0.0 | 2.47937E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47741E-07 | 3.29424E-05 | 0 |
| T/N | 25163 |
Ig-134 |
53 | None | 0.1181 | None | 0.761 | N | 0.363 | 0.285 | 0.483374165343 | gnomAD-4.0.0 | 6.84335E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15945E-05 | 0 |
| G/E | 26642 |
Ig-138 |
49 | rs778486315 |
0.3359 | -0.232 | 0.83 | N | 0.678 | 0.305 | 0.580509188723 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| G/E | 26642 |
Ig-138 |
49 | rs778486315 |
0.3359 | -0.232 | 0.83 | N | 0.678 | 0.305 | 0.580509188723 | gnomAD-4.0.0 | 1.36851E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79905E-06 | 0 | 0 |
| G/R | 26642 |
Ig-138 |
49 | None | 0.5468 | None | 0.83 | N | 0.687 | 0.389 | 0.77029934569 | gnomAD-4.0.0 | 1.59148E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85884E-06 | 0 | 0 |
| G/V | 26642 |
Ig-138 |
49 | None | 0.2304 | None | 0.709 | N | 0.687 | 0.291 | 0.7895510759 | gnomAD-4.0.0 | 6.84253E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99526E-07 | 0 | 0 |
| T/A | 26931 |
Ig-139 |
52 | rs1397026912 |
0.1596 | -0.308 | 0.958 | N | 0.366 | 0.333 | 0.29132392195 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/A | 26931 |
Ig-139 |
52 | rs1397026912 |
0.1596 | -0.308 | 0.958 | N | 0.366 | 0.333 | 0.29132392195 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 26931 |
Ig-139 |
52 | rs1397026912 |
0.1596 | -0.308 | 0.958 | N | 0.366 | 0.333 | 0.29132392195 | gnomAD-4.0.0 | 8.05682E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01721E-05 | 1.0982E-05 | 0 |
| T/I | 26931 |
Ig-139 |
52 | None | 0.4238 | None | 0.976 | N | 0.533 | 0.54 | 0.589131389434 | gnomAD-4.0.0 | 6.84272E-06 | None | None | None | None | N | None | 2.98918E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09588E-06 | 0 | 0 |
| T/A | 27328 |
Ig-140 |
51 | rs376541881 |
0.1161 | -0.525 | 0.999 | D | 0.444 | 0.433 | None | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.94E-06 | 1.66003E-04 |
| T/A | 27328 |
Ig-140 |
51 | rs376541881 |
0.1161 | -0.525 | 0.999 | D | 0.444 | 0.433 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| T/A | 27328 |
Ig-140 |
51 | rs376541881 |
0.1161 | -0.525 | 0.999 | D | 0.444 | 0.433 | None | gnomAD-4.0.0 | 4.02802E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.8315E-05 | 0 | 1.28102E-04 |
| S/A | 28014 |
Ig-142 |
52 | None | 0.1213 | None | 0.008 | N | 0.199 | 0.105 | 0.143124449307 | gnomAD-4.0.0 | 1.59255E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43398E-05 | 0 |
| T/A | 28804 |
Ig-144 |
50 | rs879038909 |
0.0906 | None | 0.63 | N | 0.423 | 0.24 | None | gnomAD-4.0.0 | 2.02969E-06 | None | None | None | None | N | None | 3.48833E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 28804 |
Ig-144 |
50 | rs879038909 |
0.4597 | None | 0.983 | N | 0.427 | 0.443 | 0.471211772063 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| T/P | 28804 |
Ig-144 |
50 | rs879038909 |
0.4597 | None | 0.983 | N | 0.427 | 0.443 | 0.471211772063 | gnomAD-4.0.0 | 6.57263E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78469E-04 |
| T/R | 28804 |
Ig-144 |
50 | rs750815763 |
0.2466 | -0.247 | 0.935 | N | 0.397 | 0.468 | 0.507628581994 | gnomAD-2.1.1 | 4.2E-06 | None | None | None | None | N | None | 0 | 2.97E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/R | 28804 |
Ig-144 |
50 | rs750815763 |
0.2466 | -0.247 | 0.935 | N | 0.397 | 0.468 | 0.507628581994 | gnomAD-4.0.0 | 1.62247E-06 | None | None | None | None | N | None | 0 | 2.3232E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 29096 |
Ig-145 |
52 | rs1575589104 |
0.124 | None | 0.999 | N | 0.436 | 0.29 | 0.352048277211 | gnomAD-4.0.0 | 1.59105E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85785E-06 | 0 | 0 |
| T/I | 29096 |
Ig-145 |
52 | None | 0.3737 | None | 1.0 | D | 0.655 | 0.474 | 0.657668229798 | gnomAD-4.0.0 | 1.59105E-06 | None | None | None | None | N | None | 5.65163E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 29492 |
Ig-146 |
49 | None | 0.1054 | None | 0.055 | N | 0.351 | 0.108 | 0.318828661733 | gnomAD-4.0.0 | 1.59154E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| T/S | 29492 |
Ig-146 |
49 | rs1700819240 |
0.0876 | None | 0.001 | N | 0.168 | 0.106 | 0.264547087235 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 29492 |
Ig-146 |
49 | rs1700819240 |
0.0876 | None | 0.001 | N | 0.168 | 0.106 | 0.264547087235 | gnomAD-4.0.0 | 6.57341E-06 | None | None | None | None | N | None | 2.41313E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 29891 |
Ig-147 |
50 | rs758970991 |
0.5739 | -0.252 | 1.0 | N | 0.658 | 0.456 | 0.547893116657 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| T/I | 29891 |
Ig-147 |
50 | rs758970991 |
0.5739 | -0.252 | 1.0 | N | 0.658 | 0.456 | 0.547893116657 | gnomAD-4.0.0 | 1.36863E-06 | None | None | None | None | N | None | 0 | 2.23604E-05 | None | 0 | 0 | None | 0 | 0 | 8.99446E-07 | 0 | 0 |
| T/N | 29891 |
Ig-147 |
50 | None | 0.1487 | None | 1.0 | N | 0.683 | 0.384 | 0.488196290542 | gnomAD-4.0.0 | 6.84313E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99446E-07 | 0 | 0 |
| T/S | 29891 |
Ig-147 |
50 | rs758970991 |
0.1292 | -0.194 | 0.999 | N | 0.461 | 0.171 | 0.388495093706 | gnomAD-4.0.0 | 1.36863E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99446E-07 | 1.15934E-05 | 0 |
| V/I | 30578 |
Ig-149 |
47 | rs727504672 |
0.0725 | 0.16 | 0.958 | N | 0.218 | 0.242 | None | gnomAD-2.1.1 | 9.27E-05 | None | None | None | None | I | None | 4.13E-05 | 2.83E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.87283E-04 | 0 |
| V/I | 30578 |
Ig-149 |
47 | rs727504672 |
0.0725 | 0.16 | 0.958 | N | 0.218 | 0.242 | None | gnomAD-3.1.2 | 1.24875E-04 | None | None | None | None | I | None | 7.24E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 1.58228E-02 | 1.32306E-04 | 0 | 4.77555E-04 |
| V/I | 30578 |
Ig-149 |
47 | rs727504672 |
0.0725 | 0.16 | 0.958 | N | 0.218 | 0.242 | None | gnomAD-4.0.0 | 9.4806E-05 | None | None | None | None | I | None | 6.66542E-05 | 1.6665E-05 | None | 0 | 4.45752E-05 | None | 3.12422E-05 | 8.25083E-04 | 1.05104E-04 | 3.29381E-05 | 1.76039E-04 |
| T/I | 30975 |
Ig-150 |
49 | None | 0.6935 | None | 0.999 | N | 0.623 | 0.496 | 0.659988389567 | gnomAD-4.0.0 | 6.84192E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99455E-07 | 0 | 0 |
| T/K | 30975 |
Ig-150 |
49 | rs761971680 |
0.5017 | -0.159 | 0.999 | D | 0.568 | 0.472 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 6.46E-05 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/K | 30975 |
Ig-150 |
49 | rs761971680 |
0.5017 | -0.159 | 0.999 | D | 0.568 | 0.472 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 2.41E-05 | 2.61883E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| T/K | 30975 |
Ig-150 |
49 | rs761971680 |
0.5017 | -0.159 | 0.999 | D | 0.568 | 0.472 | None | gnomAD-4.0.0 | 8.05575E-06 | None | None | None | None | N | None | 1.33479E-05 | 1.00017E-04 | None | 0 | 0 | None | 0 | 0 | 4.23798E-06 | 1.09784E-05 | 0 |
| T/N | 32064 |
Ig-153 |
48 | None | 0.3453 | None | 1.0 | D | 0.648 | 0.365 | 0.500613528874 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/C | 32754 |
Ig-155 |
47 | rs192952263 |
0.2198 | -0.14 | 1.0 | N | 0.436 | 0.392 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92976E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/C | 32754 |
Ig-155 |
47 | rs192952263 |
0.2198 | -0.14 | 1.0 | N | 0.436 | 0.392 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| S/C | 32754 |
Ig-155 |
47 | rs192952263 |
0.2198 | -0.14 | 1.0 | N | 0.436 | 0.392 | None | gnomAD-4.0.0 | 2.02969E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.27273E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 33248 |
Ig-157 |
46 | rs1455373620 |
0.3288 | None | 0.996 | N | 0.46 | 0.335 | 0.421060224861 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/S | 33248 |
Ig-157 |
46 | rs1455373620 |
0.3288 | None | 0.996 | N | 0.46 | 0.335 | 0.421060224861 | gnomAD-4.0.0 | 6.57246E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46994E-05 | 0 | 0 |
| E/K | 34188 |
Ig-160 |
52 | rs577667352 |
0.106 | 0.645 | 0.064 | N | 0.239 | 0.167 | 0.247322355667 | gnomAD-2.1.1 | 5.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63399E-04 | None | 0 | 7.09E-05 | 0 |
| E/K | 34188 |
Ig-160 |
52 | rs577667352 |
0.106 | 0.645 | 0.064 | N | 0.239 | 0.167 | 0.247322355667 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.1425E-04 | 0 |
| E/K | 34188 |
Ig-160 |
52 | rs577667352 |
0.106 | 0.645 | 0.064 | N | 0.239 | 0.167 | 0.247322355667 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| E/K | 34188 |
Ig-160 |
52 | rs577667352 |
0.106 | 0.645 | 0.064 | N | 0.239 | 0.167 | 0.247322355667 | gnomAD-4.0.0 | 3.03603E-05 | None | None | None | None | N | None | 0 | 1.66628E-05 | None | 0 | 2.22806E-05 | None | 1.5624E-05 | 0 | 2.28842E-05 | 1.86649E-04 | 3.20061E-05 |
| T/M | 34993 |
Ig-163 |
52 | rs368945564 |
0.0619 | 0.041 | 0.004 | N | 0.197 | 0.165 | None | gnomAD-2.1.1 | 5.22E-05 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 1.63409E-04 | None | 0 | 6.2E-05 | 0 |
| T/M | 34993 |
Ig-163 |
52 | rs368945564 |
0.0619 | 0.041 | 0.004 | N | 0.197 | 0.165 | None | gnomAD-3.1.2 | 4.6E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.9253E-04 | None | 0 | 0 | 8.82E-05 | 0 | 0 |
| T/M | 34993 |
Ig-163 |
52 | rs368945564 |
0.0619 | 0.041 | 0.004 | N | 0.197 | 0.165 | None | gnomAD-4.0.0 | 9.72742E-05 | None | None | None | None | N | None | 2.66496E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.19504E-04 | 1.20765E-04 | 4.80123E-05 |
| T/R | 34993 |
Ig-163 |
52 | None | 0.146 | None | 0.541 | N | 0.274 | 0.176 | 0.211220785272 | gnomAD-4.0.0 | 6.84147E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99399E-07 | 0 | 0 |
| T/A | 35180 |
Ig-164 |
52 | rs1473790126 |
0.0876 | -0.342 | None | N | 0.143 | 0.125 | 0.12205267543 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.85E-06 | 0 |
| T/A | 35180 |
Ig-164 |
52 | rs1473790126 |
0.0876 | -0.342 | None | N | 0.143 | 0.125 | 0.12205267543 | gnomAD-4.0.0 | 1.36827E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79878E-06 | 0 | 0 |
| T/K | 35180 |
Ig-164 |
52 | rs1575225765 |
0.2959 | None | 0.052 | N | 0.346 | 0.218 | 0.337378238328 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| D/N | 35471 |
Ig-166 |
52 | None | 0.1132 | None | None | N | 0.097 | 0.127 | 0.241078983079 | gnomAD-4.0.0 | 6.86113E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00263E-07 | 0 | 0 |
| S/L | 35656 |
Ig-167 |
50 | None | 0.1462 | None | 1.0 | N | 0.621 | 0.466 | 0.70075097299 | gnomAD-4.0.0 | 1.5942E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8659E-06 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.