Structural position:

  • Domain Type: Ig
  • Aligned Position: 35
  • Secondary Structure Element: e
  • Secondary Structure Region: β-strand B

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
I/F 29 Ig-1 24 None 0.7372 None 0.771 N 0.765 0.414 0.32714864917 gnomAD-4.0.0 1.36834E-06 None None None -1.048(TCAP) N None 0 0 None 0 0 None 0 0 1.79873E-06 0 0
I/V 29 Ig-1 24 rs1458992819 0.0932 -1.367 None N 0.243 0.18 0.144782658237 gnomAD-2.1.1 3.98E-06 None None None -0.801(TCAP) N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
I/V 29 Ig-1 24 rs1458992819 0.0932 -1.367 None N 0.243 0.18 0.144782658237 gnomAD-4.0.0 3.42086E-06 None None None -0.801(TCAP) N None 0 0 None 0 0 None 3.74434E-05 0 1.79873E-06 1.16042E-05 0
V/M 127 Ig-2 24 rs749010768 0.843 -1.135 1.0 D 0.754 0.656 0.721716469435 gnomAD-2.1.1 3.98E-06 None None None -1.464(TCAP) N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
V/M 127 Ig-2 24 rs749010768 0.843 -1.135 1.0 D 0.754 0.656 0.721716469435 gnomAD-4.0.0 4.1051E-06 None None None -1.464(TCAP) N None 0 0 None 0 0 None 0 0 5.39655E-06 0 0
I/M 966 Ig-3 24 rs144408973 0.5666 -1.016 0.998 D 0.73 0.458 None gnomAD-2.1.1 3.99E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.83E-06 0
I/N 966 Ig-3 24 None 0.9953 None 0.999 D 0.814 0.696 0.911554315766 gnomAD-4.0.0 2.40066E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62502E-06 0 0
I/V 966 Ig-3 24 rs2092911302 0.2098 None 0.333 N 0.213 0.175 0.369309618794 gnomAD-4.0.0 3.1811E-06 None None None None N None 0 2.28624E-05 None 0 0 None 0 0 2.85659E-06 0 0
V/A 1105 Ig-4 24 rs1263142800 0.5925 -2.14 0.104 N 0.665 0.364 0.514240282655 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/A 1105 Ig-4 24 rs1263142800 0.5925 -2.14 0.104 N 0.665 0.364 0.514240282655 gnomAD-4.0.0 5.47256E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39577E-06 1.15931E-05 1.65585E-05
M/I 1314 Ig-5 24 rs761039819 0.6894 -0.723 0.454 N 0.601 0.27 0.365703291355 gnomAD-2.1.1 4E-06 None None None None N None 0 0 None 0 5.45E-05 None 0 None 0 0 0
M/I 1314 Ig-5 24 rs761039819 0.6894 -0.723 0.454 N 0.601 0.27 0.365703291355 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92456E-04 None 0 0 0 0 0
M/I 1314 Ig-5 24 rs761039819 0.6894 -0.723 0.454 N 0.601 0.27 0.365703291355 gnomAD-4.0.0 4.06013E-06 None None None None N None 0 0 None 0 1.13302E-04 None 0 0 3.61503E-06 0 0
M/V 1314 Ig-5 24 rs764249439 0.1995 -1.176 0.022 N 0.326 0.259 None gnomAD-2.1.1 2.13E-05 None None None None N None 2.44519E-04 0 None 0 0 None 0 None 0 0 0
M/V 1314 Ig-5 24 rs764249439 0.1995 -1.176 0.022 N 0.326 0.259 None gnomAD-3.1.2 1.05132E-04 None None None None N None 3.61934E-04 6.55E-05 0 0 0 None 0 0 0 0 0
M/V 1314 Ig-5 24 rs764249439 0.1995 -1.176 0.022 N 0.326 0.259 None gnomAD-4.0.0 1.73515E-05 None None None None N None 3.33725E-04 1.66722E-05 None 0 0 None 0 0 0 0 3.20092E-05
V/A 1480 Ig-6 24 None 0.8169 None 0.999 D 0.601 0.61 0.746554498716 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
V/L 1480 Ig-6 24 None 0.9003 None 0.997 D 0.627 0.55 0.689064770846 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/V 1579 Ig-7 24 rs2092328380 0.5815 None 1.0 N 0.619 0.365 0.412328234245 gnomAD-4.0.0 2.05228E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99323E-07 0 3.31159E-05
L/V 1726 Ig-8 24 rs2092262370 0.3106 None 0.999 N 0.55 0.362 0.294206760003 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
L/V 1726 Ig-8 24 rs2092262370 0.3106 None 0.999 N 0.55 0.362 0.294206760003 gnomAD-4.0.0 2.02974E-06 None None None None N None 1.7466E-05 0 None 0 0 None 0 0 0 0 3.40252E-05
V/I 1864 Ig-9 24 rs2092215067 0.1352 None 0.997 N 0.535 0.375 0.638969403159 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
T/A 2198 Ig-11 25 None 0.4056 None 0.995 N 0.631 0.231 0.257292322809 gnomAD-4.0.0 1.36823E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79865E-06 0 0
T/I 2198 Ig-11 25 rs886038879 0.6904 -0.251 0.994 N 0.785 0.375 0.435262743402 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14811E-04 0 None 0 0 None 0 None 0 0 0
T/I 2198 Ig-11 25 rs886038879 0.6904 -0.251 0.994 N 0.785 0.375 0.435262743402 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/I 2198 Ig-11 25 rs886038879 0.6904 -0.251 0.994 N 0.785 0.375 0.435262743402 gnomAD-4.0.0 2.56157E-06 None None None None N None 1.69205E-05 0 None 0 0 None 0 0 2.39188E-06 0 0
T/S 2198 Ig-11 25 None 0.5302 None 0.998 D 0.638 0.311 0.370051654043 gnomAD-4.0.0 6.84115E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99324E-07 0 0
V/L 2379 Ig-13 24 None 0.2357 None 0.002 D 0.319 0.235 0.289847578895 gnomAD-4.0.0 4.10452E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39586E-06 0 0
V/A 2468 Ig-14 24 rs886055300 0.7523 None 0.78 D 0.667 0.532 0.624260124922 gnomAD-4.0.0 3.18148E-06 None None None None N None 0 0 None 0 0 None 0 4.82393E-04 0 0 0
V/L 2468 Ig-14 24 rs1420278166 0.4314 -0.898 0.011 N 0.311 0.322 0.296329037015 gnomAD-2.1.1 3.99E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
V/L 2468 Ig-14 24 rs1420278166 0.4314 -0.898 0.011 N 0.311 0.322 0.296329037015 gnomAD-4.0.0 1.36822E-06 None None None None N None 0 2.23674E-05 None 0 0 None 0 0 8.99319E-07 0 0
V/M 2468 Ig-14 24 rs1420278166 0.4636 None 0.968 D 0.719 0.49 0.574600906166 gnomAD-4.0.0 6.84112E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99319E-07 0 0
V/F 2643 Ig-16 23 rs886042338 0.711 -1.526 1.0 D 0.832 0.621 0.782848552693 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.81E-06 0
V/F 2643 Ig-16 23 rs886042338 0.711 -1.526 1.0 D 0.832 0.621 0.782848552693 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/P 2730 Ig-17 24 None 0.9904 None 1.0 D 0.851 0.816 0.8892766192 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 2905 Ig-19 24 None 0.9501 None 0.999 D 0.612 0.674 0.728496969568 gnomAD-4.0.0 1.59052E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85651E-06 0 0
V/L 2905 Ig-19 24 rs369380469 0.9274 None 0.997 N 0.623 0.424 0.582828786496 gnomAD-4.0.0 2.05221E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69789E-06 0 0
V/M 2905 Ig-19 24 rs369380469 0.9308 -0.997 1.0 D 0.787 0.592 None gnomAD-2.1.1 1.06E-05 None None None None N None 4.01E-05 0 None 0 0 None 0 None 0 1.55E-05 0
V/M 2905 Ig-19 24 rs369380469 0.9308 -0.997 1.0 D 0.787 0.592 None gnomAD-3.1.2 1.31E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
V/M 2905 Ig-19 24 rs369380469 0.9308 -0.997 1.0 D 0.787 0.592 None gnomAD-4.0.0 5.5763E-06 None None None None N None 1.33518E-05 0 None 0 6.68419E-05 None 0 0 4.23727E-06 0 0
V/I 3081 Ig-21 24 rs1037728221 0.1102 None 0.001 N 0.246 0.154 0.210429274316 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/I 3081 Ig-21 24 rs1037728221 0.1102 None 0.001 N 0.246 0.154 0.210429274316 gnomAD-4.0.0 2.56121E-06 None None None None N None 1.69102E-05 0 None 0 2.42542E-05 None 0 0 0 0 0
V/A 3170 Ig-22 24 rs779339626 0.9166 -2.3 0.999 D 0.588 0.697 None gnomAD-2.1.1 2.48E-05 None None None None N None 0 0 None 0 0 None 0 None 0 5.44E-05 0
V/A 3170 Ig-22 24 rs779339626 0.9166 -2.3 0.999 D 0.588 0.697 None gnomAD-3.1.2 3.94E-05 None None None None N None 0 0 0 0 0 None 0 0 8.82E-05 0 0
V/A 3170 Ig-22 24 rs779339626 0.9166 -2.3 0.999 D 0.588 0.697 None gnomAD-4.0.0 6.13403E-05 None None None None N None 0 0 None 0 0 None 0 0 8.13562E-05 0 4.80184E-05
V/L 3170 Ig-22 24 None 0.92 None 0.997 D 0.601 0.477 0.593829253334 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31252E-06 0 0
I/L 3262 Ig-23 24 None 0.2412 None 0.19 N 0.393 0.222 0.54988173901 gnomAD-4.0.0 4.80129E-06 None None None None N None 0 0 None 0 0 None 0 0 5.25001E-06 0 0
V/A 3368 Ig-24 24 rs149309988 0.7317 -2.4 0.999 D 0.614 0.644 None gnomAD-2.1.1 3.98E-06 None None None None N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
V/A 3368 Ig-24 24 rs149309988 0.7317 -2.4 0.999 D 0.614 0.644 None gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
V/A 3368 Ig-24 24 rs149309988 0.7317 -2.4 0.999 D 0.614 0.644 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
V/A 3368 Ig-24 24 rs149309988 0.7317 -2.4 0.999 D 0.614 0.644 None gnomAD-4.0.0 2.02961E-06 None None None None N None 3.48736E-05 0 None 0 0 None 0 0 0 0 0
V/F 3368 Ig-24 24 None 0.7462 None 1.0 D 0.851 0.594 0.884733524946 gnomAD-4.0.0 6.84086E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99326E-07 0 0
V/I 3368 Ig-24 24 rs771921268 0.1127 -0.363 0.997 N 0.556 0.296 0.552980905328 gnomAD-2.1.1 7.96E-06 None None None None N None 0 0 None 0 0 None 6.53E-05 None 0 0 0
V/I 3368 Ig-24 24 rs771921268 0.1127 -0.363 0.997 N 0.556 0.296 0.552980905328 gnomAD-4.0.0 4.10452E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79865E-06 4.63725E-05 0
V/L 3368 Ig-24 24 rs771921268 0.5384 -0.366 0.997 D 0.629 0.437 0.574945690627 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 3368 Ig-24 24 rs771921268 0.5384 -0.366 0.997 D 0.629 0.437 0.574945690627 gnomAD-4.0.0 1.2392E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69495E-06 0 0
V/F 3488 Ig-25 24 None 0.7184 None None None None 0.451 None gnomAD-4.0.0 1.59129E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85847E-06 0 0
L/S 3683 Ig-26 24 rs2154334861 0.4044 None None None None 0.145 None gnomAD-4.0.0 1.59133E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85806E-06 0 0
V/A 3843 Ig-27 24 rs766747906 0.2009 -2.714 0.002 D 0.303 0.19 None gnomAD-2.1.1 2.14E-05 None None None None N None 0 0 None 0 3.07913E-04 None 0 None 0 0 0
V/A 3843 Ig-27 24 rs766747906 0.2009 -2.714 0.002 D 0.303 0.19 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 1.92827E-04 None 0 0 0 0 0
V/A 3843 Ig-27 24 rs766747906 0.2009 -2.714 0.002 D 0.303 0.19 None gnomAD-4.0.0 3.84354E-06 None None None None N None 0 0 None 0 7.27555E-05 None 0 0 0 0 0
V/M 3961 Ig-28 24 rs1017307763 0.3783 None 0.982 D 0.746 0.428 None gnomAD-4.0.0 2.05252E-06 None None None None I None 5.97514E-05 0 None 0 2.5194E-05 None 0 0 0 0 0
I/T 4629 Ig-29 24 rs994541516 0.7328 -2.773 1.0 D 0.779 0.6 None gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
I/T 4629 Ig-29 24 rs994541516 0.7328 -2.773 1.0 D 0.779 0.6 None gnomAD-4.0.0 1.36842E-06 None None None None N None 2.98704E-05 0 None 0 0 None 0 0 8.99446E-07 0 0
I/V 4629 Ig-29 24 rs774964232 0.0881 -1.677 0.993 N 0.339 0.219 None gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
I/V 4629 Ig-29 24 rs774964232 0.0881 -1.677 0.993 N 0.339 0.219 None gnomAD-4.0.0 1.59126E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85804E-06 0 0
I/T 4723 Ig-30 24 None 0.6146 None 0.001 N 0.419 0.425 0.625221479056 gnomAD-4.0.0 1.59196E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85896E-06 0 0
V/I 4911 Ig-32 24 rs2081325701 0.0966 None 0.014 D 0.241 0.202 0.468003879618 gnomAD-4.0.0 3.4212E-06 None None None None N None 0 0 None 0 2.52169E-05 None 0 0 3.59788E-06 0 0
L/V 5005 Ig-33 25 rs1449279284 0.1154 -0.967 0.006 N 0.255 0.163 0.0846915920261 gnomAD-2.1.1 4.07E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.04E-06 0
L/V 5005 Ig-33 25 rs1449279284 0.1154 -0.967 0.006 N 0.255 0.163 0.0846915920261 gnomAD-4.0.0 1.3694E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79972E-06 0 0
V/A 5098 Ig-34 24 rs1349400261 0.6218 -1.709 0.104 D 0.68 0.361 0.544432747571 gnomAD-2.1.1 8.11E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.79E-05 0
V/A 5098 Ig-34 24 rs1349400261 0.6218 -1.709 0.104 D 0.68 0.361 0.544432747571 gnomAD-4.0.0 6.16535E-06 None None None None N None 0 0 None 0 0 None 0 0 8.10272E-06 0 0
V/G 5191 Ig-35 24 None 0.8174 None 0.928 D 0.849 0.774 0.937896326255 gnomAD-4.0.0 6.00161E-06 None None None None N None 0 0 None 0 0 None 0 0 6.56251E-06 0 0
V/A 5284 Ig-36 24 rs1327029023 0.4395 -1.642 0.977 D 0.673 0.563 0.741158856741 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
V/A 5284 Ig-36 24 rs1327029023 0.4395 -1.642 0.977 D 0.673 0.563 0.741158856741 gnomAD-4.0.0 1.59121E-06 None None None None N None 0 2.28645E-05 None 0 0 None 0 0 0 0 0
V/G 5284 Ig-36 24 rs1327029023 0.8284 -2.428 0.999 D 0.823 0.691 0.944711328919 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/G 5284 Ig-36 24 rs1327029023 0.8284 -2.428 0.999 D 0.823 0.691 0.944711328919 gnomAD-4.0.0 1.59121E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
V/M 5284 Ig-36 24 rs66839174 0.5098 0.107 0.997 D 0.708 0.457 None gnomAD-2.1.1 1.15733E-03 None None None None N None 1.23181E-02 6.78848E-04 None 0 0 None 0 None 0 0 2.81057E-04
V/M 5284 Ig-36 24 rs66839174 0.5098 0.107 0.997 D 0.708 0.457 None gnomAD-3.1.2 3.63452E-03 None None None None N None 1.23311E-02 2.42305E-03 0 0 0 None 0 0 0 0 2.39234E-03
V/M 5284 Ig-36 24 rs66839174 0.5098 0.107 0.997 D 0.708 0.457 None 1000 genomes 3.59425E-03 None None None None N None 1.13E-02 4.3E-03 None None 0 0 None None None 0 None
V/M 5284 Ig-36 24 rs66839174 0.5098 0.107 0.997 D 0.708 0.457 None gnomAD-4.0.0 6.51248E-04 None None None None N None 1.22881E-02 1.16647E-03 None 0 0 None 0 4.95376E-04 2.54282E-06 1.09801E-05 8.32266E-04
I/T 5380 Ig-37 24 rs767107151 0.6172 -2.374 0.896 N 0.727 0.498 0.695068833554 gnomAD-2.1.1 2.02E-05 None None None None N None 0 0 None 0 2.80426E-04 None 0 None 0 0 0
I/T 5380 Ig-37 24 rs767107151 0.6172 -2.374 0.896 N 0.727 0.498 0.695068833554 gnomAD-4.0.0 7.96105E-06 None None None None N None 0 0 None 0 1.11247E-04 None 0 0 2.8592E-06 0 0
I/V 5380 Ig-37 24 rs1280725528 0.088 None 0.004 N 0.233 0.112 0.348983352498 gnomAD-4.0.0 1.59225E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85923E-06 0 0
V/L 5567 Ig-39 25 None 0.4979 None 0.026 D 0.302 0.354 0.508398094826 gnomAD-4.0.0 1.59152E-06 None None None None N None 0 0 None 0 2.77346E-05 None 0 0 0 0 0
V/L 5660 Ig-40 24 None 0.3036 None 0.217 D 0.292 0.328 0.469415673434 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
L/Q 5753 Ig-41 24 None 0.9396 None 0.995 D 0.806 0.566 0.82834384376 gnomAD-4.0.0 6.84338E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99543E-07 0 0
L/R 5753 Ig-41 24 None 0.9616 None 0.984 D 0.813 0.628 0.813981597967 gnomAD-4.0.0 6.84338E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99543E-07 0 0
F/L 5846 Ig-42 24 None 0.9798 None 0.978 N 0.635 0.277 0.405012372841 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
V/L 5942 Ig-43 24 None 0.696 None 0.997 D 0.639 0.552 0.652866637519 gnomAD-4.0.0 6.84311E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99569E-07 0 0
V/A 6035 Ig-44 24 rs1207028301 0.1895 -2.166 0.78 N 0.686 0.526 0.556932860221 gnomAD-2.1.1 4.08E-06 None None None None N None 6.52E-05 0 None 0 0 None 0 None 0 0 0
V/A 6035 Ig-44 24 rs1207028301 0.1895 -2.166 0.78 N 0.686 0.526 0.556932860221 gnomAD-4.0.0 1.5956E-06 None None None None N None 5.65867E-05 0 None 0 0 None 0 0 0 0 0
V/L 6035 Ig-44 24 rs909868763 0.2847 None 0.011 D 0.249 0.385 0.307332253619 gnomAD-4.0.0 6.85042E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00106E-07 0 0
V/M 6035 Ig-44 24 rs909868763 0.2552 None 0.437 D 0.431 0.524 0.428630128466 gnomAD-4.0.0 1.37008E-06 None None None None N None 2.98918E-05 0 None 0 0 None 0 1.73671E-04 0 0 0
I/V 6129 Ig-45 25 rs2080081483 0.0825 None None N 0.215 0.066 0.223847106136 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 6129 Ig-45 25 rs2080081483 0.0825 None None N 0.215 0.066 0.223847106136 gnomAD-4.0.0 2.02988E-06 None None None None N None 3.49406E-05 0 None 0 0 None 0 0 0 0 0
V/A 6222 Ig-46 24 None 0.4316 None 0.994 N 0.655 0.537 0.689150956925 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/M 6315 Ig-47 24 rs770552574 0.3169 -0.461 0.996 D 0.787 0.529 0.617849357852 gnomAD-2.1.1 1.64E-05 None None None None N None 0 0 None 0 1.13507E-04 None 6.66E-05 None 0 0 0
V/M 6315 Ig-47 24 rs770552574 0.3169 -0.461 0.996 D 0.787 0.529 0.617849357852 gnomAD-4.0.0 1.37044E-05 None None None None N None 0 0 None 0 5.05663E-05 None 0 0 1.35023E-05 3.49577E-05 0
V/A 6408 Ig-48 24 None 0.5739 None 0.999 D 0.613 0.612 0.706496497531 gnomAD-4.0.0 6.84496E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15966E-05 0
V/G 6408 Ig-48 24 None 0.8837 None 1.0 D 0.857 0.836 0.882822177023 gnomAD-4.0.0 1.36899E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79961E-06 0 0
V/M 6408 Ig-48 24 rs2154306642 0.7296 None 1.0 D 0.767 0.589 0.739150905744 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
V/L 6504 Ig-49 24 rs762156103 0.3111 -0.398 0.031 D 0.459 0.418 0.305730143919 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.96E-06 0
V/L 6504 Ig-49 24 rs762156103 0.3111 -0.398 0.031 D 0.459 0.418 0.305730143919 gnomAD-4.0.0 6.84548E-07 None None None None N None 0 0 None 0 2.52372E-05 None 0 0 0 0 0
L/I 6597 Ig-50 24 None 0.1075 None 0.64 N 0.714 0.141 0.39843156188 gnomAD-4.0.0 6.00161E-06 None None None None N None 0 0 None 0 0 None 0 0 6.56251E-06 0 0
L/P 6597 Ig-50 24 rs745676008 0.8883 -1.095 0.995 N 0.83 0.572 0.690133245405 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.9E-06 0
L/P 6597 Ig-50 24 rs745676008 0.8883 -1.095 0.995 N 0.83 0.572 0.690133245405 gnomAD-4.0.0 2.6012E-05 None None None None N None 0 0 None 0 0 None 0 0 3.41923E-05 0 0
I/T 6691 Ig-51 25 None 0.7165 None 0.954 D 0.693 0.448 0.551550886788 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 6.17284E-04 0 0 0
I/V 6691 Ig-51 25 rs1429994006 0.1048 None None N 0.199 0.155 0.32471235697 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 6691 Ig-51 25 rs1429994006 0.1048 None None N 0.199 0.155 0.32471235697 gnomAD-4.0.0 4.05997E-06 None None None None N None 1.74715E-05 0 None 0 0 None 0 0 3.6149E-06 0 0
L/F 6784 Ig-52 24 None 0.3242 None 0.969 N 0.783 0.309 0.371903410333 gnomAD-4.0.0 1.37097E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80139E-06 0 0
I/L 6877 Ig-53 24 None 0.2068 None 0.002 N 0.242 0.199 0.247322355667 gnomAD-4.0.0 2.73887E-06 None None None None N None 0 0 None 0 0 None 0 0 3.59954E-06 0 0
I/M 6877 Ig-53 24 rs1227070261 0.1918 -1.258 0.81 N 0.697 0.386 0.394536629495 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.58E-05 None 0 None 0 0 0
I/T 6877 Ig-53 24 rs142794598 0.2759 -2.823 0.549 N 0.715 0.4 None gnomAD-2.1.1 3.5868E-04 None None None None N None 3.72794E-03 2.27609E-04 None 0 0 None 0 None 0 7.85E-06 1.41683E-04
I/T 6877 Ig-53 24 rs142794598 0.2759 -2.823 0.549 N 0.715 0.4 None gnomAD-3.1.2 1.01932E-03 None None None None N None 3.57298E-03 3.93494E-04 0 0 0 None 0 0 0 0 4.78011E-04
I/T 6877 Ig-53 24 rs142794598 0.2759 -2.823 0.549 N 0.715 0.4 None 1000 genomes 1.99681E-03 None None None None N None 7.6E-03 0 None None 0 0 None None None 0 None
I/T 6877 Ig-53 24 rs142794598 0.2759 -2.823 0.549 N 0.715 0.4 None gnomAD-4.0.0 1.80456E-04 None None None None N None 3.48316E-03 2.3377E-04 None 0 0 None 0 1.65508E-04 5.93619E-06 0 1.28139E-04
I/V 6877 Ig-53 24 rs1023569847 0.0556 None 0.001 N 0.223 0.164 0.233150807113 gnomAD-4.0.0 1.36944E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99884E-07 0 1.65772E-05
V/A 6971 Ig-54 24 None 0.4129 None 0.951 N 0.666 0.546 0.609443766403 gnomAD-4.0.0 1.59241E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86033E-06 0 0
V/M 6971 Ig-54 24 None 0.5944 None 0.988 D 0.694 0.487 0.623514155702 gnomAD-4.0.0 1.59247E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43365E-05 0
I/T 7160 Ig-56 24 None 0.8005 None 0.642 D 0.675 0.435 0.734902578319 gnomAD-4.0.0 2.40065E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
V/A 7346 Ig-58 24 rs1253051189 0.5839 None 0.636 N 0.698 0.486 0.609565839933 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/A 7346 Ig-58 24 rs1253051189 0.5839 None 0.636 N 0.698 0.486 0.609565839933 gnomAD-4.0.0 2.47973E-06 None None None None N None 5.34131E-05 0 None 0 0 None 0 0 0 0 0
I/T 7632 Ig-61 25 rs561354716 0.9364 -2.785 0.998 N 0.731 0.484 0.62839878287 gnomAD-2.1.1 1.07E-05 None None None None N None 1.24039E-04 0 None 0 0 None 0 None 0 0 0
I/T 7632 Ig-61 25 rs561354716 0.9364 -2.785 0.998 N 0.731 0.484 0.62839878287 gnomAD-3.1.2 2.63E-05 None None None None N None 9.65E-05 0 0 0 0 None 0 0 0 0 0
I/T 7632 Ig-61 25 rs561354716 0.9364 -2.785 0.998 N 0.731 0.484 0.62839878287 1000 genomes 3.99361E-04 None None None None N None 1.5E-03 0 None None 0 0 None None None 0 None
I/T 7632 Ig-61 25 rs561354716 0.9364 -2.785 0.998 N 0.731 0.484 0.62839878287 gnomAD-4.0.0 5.07426E-06 None None None None N None 8.71992E-05 0 None 0 0 None 0 0 0 0 0
I/M 7725 Ig-62 24 rs1270184889 0.2155 None 0.81 N 0.673 0.362 0.449669948863 gnomAD-4.0.0 1.59241E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85999E-06 0 0
I/T 7725 Ig-62 24 None 0.913 None 0.549 N 0.669 0.423 0.631214040921 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
V/A 7818 Ig-63 24 None 0.4745 None 0.76 D 0.643 0.512 0.699956752411 gnomAD-4.0.0 1.5915E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85871E-06 0 0
V/M 7818 Ig-63 24 rs748019401 0.4876 -0.43 0.997 D 0.747 0.514 0.681819901562 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/M 7818 Ig-63 24 rs748019401 0.4876 -0.43 0.997 D 0.747 0.514 0.681819901562 gnomAD-4.0.0 1.5915E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85871E-06 0 0
V/L 7912 Ig-64 24 rs797001857 0.4674 0.053 0.9 D 0.634 0.414 0.653643074943 gnomAD-2.1.1 3.18E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
V/L 7912 Ig-64 24 rs797001857 0.4674 0.053 0.9 D 0.634 0.414 0.653643074943 gnomAD-3.1.2 1.31E-05 None None None None N None 4.82E-05 0 0 0 0 None 0 0 0 0 0
V/L 7912 Ig-64 24 rs797001857 0.4674 0.053 0.9 D 0.634 0.414 0.653643074943 gnomAD-4.0.0 5.12538E-06 None None None None N None 3.38249E-05 0 None 0 0 None 0 0 4.78719E-06 0 0
V/D 8008 Ig-65 24 rs767654858 0.9846 -2.434 0.997 D 0.83 0.774 0.857379640909 gnomAD-2.1.1 1.61E-05 None None None None N None 0 1.15895E-04 None 0 0 None 0 None 0 0 0
V/D 8008 Ig-65 24 rs767654858 0.9846 -2.434 0.997 D 0.83 0.774 0.857379640909 gnomAD-4.0.0 7.95631E-06 None None None None N None 0 9.1462E-05 None 0 0 None 0 0 0 0 3.02425E-05
V/I 8008 Ig-65 24 rs775395125 0.0819 -0.482 0.02 N 0.186 0.214 0.443285836454 gnomAD-2.1.1 1.61E-05 None None None None N None 0 1.15902E-04 None 0 0 None 0 None 0 0 0
V/I 8008 Ig-65 24 rs775395125 0.0819 -0.482 0.02 N 0.186 0.214 0.443285836454 gnomAD-4.0.0 7.95631E-06 None None None None N None 0 9.1462E-05 None 0 0 None 0 0 0 0 3.02407E-05
I/N 8101 Ig-66 24 rs200423910 0.9278 -1.787 0.295 D 0.806 0.506 0.819652658057 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
I/N 8101 Ig-66 24 rs200423910 0.9278 -1.787 0.295 D 0.806 0.506 0.819652658057 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/N 8101 Ig-66 24 rs200423910 0.9278 -1.787 0.295 D 0.806 0.506 0.819652658057 gnomAD-4.0.0 1.17767E-05 None None None None N None 0 0 None 0 0 None 0 0 1.52587E-05 0 1.60154E-05
I/T 8101 Ig-66 24 rs200423910 0.7964 -2.089 0.055 D 0.669 0.355 0.723157768034 gnomAD-2.1.1 8.07E-06 None None None None N None 6.48E-05 0 None 0 0 None 0 None 0 8.92E-06 0
I/T 8101 Ig-66 24 rs200423910 0.7964 -2.089 0.055 D 0.669 0.355 0.723157768034 gnomAD-4.0.0 5.47475E-06 None None None None N None 2.989E-05 0 None 0 0 None 0 0 6.2969E-06 0 0
Y/H 8194 Ig-67 24 rs763264570 0.6782 -1.74 0.295 N 0.647 0.307 0.31291088546 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
Y/H 8194 Ig-67 24 rs763264570 0.6782 -1.74 0.295 N 0.647 0.307 0.31291088546 gnomAD-4.0.0 1.59144E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85848E-06 0 0
V/A 8287 Ig-68 24 rs2077779717 0.7417 None 0.95 N 0.673 0.485 0.631562779424 gnomAD-4.0.0 1.60527E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85909E-06 0 0
I/M 8383 Ig-69 24 rs555511234 0.2124 -1.089 0.997 N 0.735 0.525 0.464098490096 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
I/M 8383 Ig-69 24 rs555511234 0.2124 -1.089 0.997 N 0.735 0.525 0.464098490096 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
I/M 8383 Ig-69 24 rs555511234 0.2124 -1.089 0.997 N 0.735 0.525 0.464098490096 gnomAD-4.0.0 1.23968E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.09876E-05 1.60133E-05
I/T 8383 Ig-69 24 rs760613642 0.9131 -2.67 1.0 N 0.771 0.571 0.640746855568 gnomAD-2.1.1 4.86E-05 None None None None N None 0 0 None 0 0 None 3.93185E-04 None 0 0 0
I/T 8383 Ig-69 24 rs760613642 0.9131 -2.67 1.0 N 0.771 0.571 0.640746855568 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06868E-04 0
I/T 8383 Ig-69 24 rs760613642 0.9131 -2.67 1.0 N 0.771 0.571 0.640746855568 gnomAD-4.0.0 1.85958E-05 None None None None N None 0 0 None 0 0 None 0 0 0 3.29569E-04 0
I/V 8383 Ig-69 24 rs886038829 0.1101 -1.412 0.069 N 0.249 0.085 0.316494231283 gnomAD-2.1.1 8.09E-06 None None None None N None 0 2.91E-05 None 0 5.59E-05 None 0 None 0 0 0
I/V 8383 Ig-69 24 rs886038829 0.1101 -1.412 0.069 N 0.249 0.085 0.316494231283 gnomAD-4.0.0 3.18468E-06 None None None None N None 0 2.28791E-05 None 0 2.77485E-05 None 0 0 0 0 0
V/I 8479 Ig-70 24 rs990182590 0.0844 None None D 0.387 0.149 0.303123707472 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 3.28947E-03 0 0 None 0 0 0 0 0
V/I 8479 Ig-70 24 rs990182590 0.0844 None None D 0.387 0.149 0.303123707472 gnomAD-4.0.0 1.97148E-05 None None None None N None 0 0 None 0 0 None 0 0 0 0 0
I/L 8573 Ig-71 25 rs142609645 0.2224 -0.557 0.009 N 0.453 0.236 None gnomAD-2.1.1 1.1E-05 None None None None N None 1.27378E-04 0 None 0 0 None 0 None 0 0 0
I/L 8573 Ig-71 25 rs142609645 0.2224 -0.557 0.009 N 0.453 0.236 None gnomAD-3.1.2 7.23E-05 None None None None N None 2.65393E-04 0 0 0 0 None 0 0 0 0 0
I/L 8573 Ig-71 25 rs142609645 0.2224 -0.557 0.009 N 0.453 0.236 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
I/L 8573 Ig-71 25 rs142609645 0.2224 -0.557 0.009 N 0.453 0.236 None gnomAD-4.0.0 8.07615E-06 None None None None N None 1.73356E-04 0 None 0 0 None 0 0 0 0 0
L/F 8666 Ig-72 24 None 0.4544 None 0.998 D 0.765 0.299 0.515603885326 gnomAD-4.0.0 2.73703E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79908E-06 2.31906E-05 0
I/M 8759 Ig-73 24 None 0.1074 None 0.019 N 0.661 0.212 0.184867976434 gnomAD-4.0.0 1.59203E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85933E-06 0 0
I/T 8759 Ig-73 24 rs199918663 0.129 -2.897 None D 0.424 0.345 None gnomAD-2.1.1 2.86E-05 None None None None N None 0 0 None 0 2.56437E-04 None 6.54E-05 None 0 7.83E-06 0
I/T 8759 Ig-73 24 rs199918663 0.129 -2.897 None D 0.424 0.345 None gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 3.85951E-04 None 0 0 0 0 0
I/T 8759 Ig-73 24 rs199918663 0.129 -2.897 None D 0.424 0.345 None gnomAD-4.0.0 2.29343E-05 None None None None N None 0 0 None 0 6.46312E-04 None 0 0 1.69548E-06 5.49113E-05 1.60154E-05
I/V 8759 Ig-73 24 rs1317485542 0.0534 -1.533 None N 0.199 0.079 0.154104182512 gnomAD-2.1.1 1.43E-05 None None None None N None 0 2.84E-05 None 0 0 None 0 None 8.02E-05 0 1.40885E-04
I/V 8759 Ig-73 24 rs1317485542 0.0534 -1.533 None N 0.199 0.079 0.154104182512 gnomAD-3.1.2 1.31E-05 None None None None N None 0 6.55E-05 0 0 0 None 9.41E-05 0 0 0 0
I/V 8759 Ig-73 24 rs1317485542 0.0534 -1.533 None N 0.199 0.079 0.154104182512 gnomAD-4.0.0 8.97144E-06 None None None None N None 0 1.6956E-05 None 0 0 None 7.85275E-05 0 0 0 2.84592E-05
V/I 8853 Ig-74 24 None 0.1058 None 0.948 N 0.589 0.287 0.597372938306 gnomAD-4.0.0 6.84261E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99502E-07 0 0
V/L 8853 Ig-74 24 rs757381520 0.4937 -0.19 0.9 D 0.627 0.348 0.587811542155 gnomAD-2.1.1 2.41E-05 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 4.44E-05 0
V/L 8853 Ig-74 24 rs757381520 0.4937 -0.19 0.9 D 0.627 0.348 0.587811542155 gnomAD-4.0.0 6.84261E-06 None None None None N None 0 2.23724E-05 None 0 0 None 0 0 8.09552E-06 0 0
V/L 8949 Ig-75 24 rs781692388 0.5279 -0.509 0.071 D 0.315 0.33 None gnomAD-2.1.1 1.14E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.51E-05 0
V/L 8949 Ig-75 24 rs781692388 0.5279 -0.509 0.071 D 0.315 0.33 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
V/L 8949 Ig-75 24 rs781692388 0.5279 -0.509 0.071 D 0.315 0.33 None gnomAD-4.0.0 3.86317E-05 None None None None N None 0 0 None 0 0 None 0 0 5.19094E-05 0 1.60834E-05
V/I 9042 Ig-76 24 rs766095051 0.0598 0.321 0.001 N 0.238 0.169 None gnomAD-2.1.1 4.3E-05 None None None None N None 4.14E-05 5.69E-05 None 0 0 None 1.64322E-04 None 0 2.36E-05 1.41363E-04
V/I 9042 Ig-76 24 rs766095051 0.0598 0.321 0.001 N 0.238 0.169 None gnomAD-3.1.2 3.29E-05 None None None None N None 2.41E-05 0 0 0 0 None 0 0 4.41E-05 2.06868E-04 0
V/I 9042 Ig-76 24 rs766095051 0.0598 0.321 0.001 N 0.238 0.169 None gnomAD-4.0.0 2.60334E-05 None None None None N None 3.99851E-05 8.34307E-05 None 0 0 None 0 0 1.44118E-05 1.7589E-04 1.60113E-05
F/L 9135 Ig-77 24 None 0.9362 None 0.055 N 0.675 0.19 0.251116650651 gnomAD-4.0.0 2.40065E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
L/P 9228 Ig-78 24 rs756143599 0.9446 -1.866 0.741 N 0.823 0.515 0.786464674917 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
L/P 9228 Ig-78 24 rs756143599 0.9446 -1.866 0.741 N 0.823 0.515 0.786464674917 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
L/P 9228 Ig-78 24 rs756143599 0.9446 -1.866 0.741 N 0.823 0.515 0.786464674917 gnomAD-4.0.0 7.68628E-06 None None None None N None 1.69073E-05 0 None 0 0 None 0 0 1.19644E-05 0 0
I/L 9324 Ig-79 24 None 0.1479 None 0.025 None 0.409 0.211 0.0716867268079 gnomAD-4.0.0 6.8422E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15977E-05 0
I/M 9324 Ig-79 24 None 0.2816 None 0.497 None 0.727 0.272 0.284539287134 gnomAD-4.0.0 1.59132E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85838E-06 0 0
I/T 9324 Ig-79 24 rs761548797 0.8528 -2.604 0.124 None 0.738 0.292 0.647371783203 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
I/T 9324 Ig-79 24 rs761548797 0.8528 -2.604 0.124 None 0.738 0.292 0.647371783203 gnomAD-4.0.0 1.59129E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85835E-06 0 0
I/V 9324 Ig-79 24 rs765190829 0.0823 -1.515 None None 0.243 0.135 0.0806252709748 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
I/V 9324 Ig-79 24 rs765190829 0.0823 -1.515 None None 0.243 0.135 0.0806252709748 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/V 9324 Ig-79 24 rs765190829 0.0823 -1.515 None None 0.243 0.135 0.0806252709748 gnomAD-4.0.0 6.81668E-06 None None None None N None 0 0 None 0 0 None 0 0 9.32388E-06 0 0
V/G 9420 Ig-80 24 None 0.8409 None 0.815 None 0.798 0.563 0.910719852269 gnomAD-4.0.0 1.59106E-06 None None None None N None 0 0 None 4.76599E-05 0 None 0 0 0 0 0
V/I 9420 Ig-80 24 rs777186750 0.0817 -0.771 0.016 None 0.266 0.121 0.218112801441 gnomAD-2.1.1 2.5E-05 None None None None N None 1.23998E-04 0 None 0 0 None 6.54E-05 None 0 1.56E-05 0
V/I 9420 Ig-80 24 rs777186750 0.0817 -0.771 0.016 None 0.266 0.121 0.218112801441 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/I 9420 Ig-80 24 rs777186750 0.0817 -0.771 0.016 None 0.266 0.121 0.218112801441 gnomAD-4.0.0 3.71812E-06 None None None None N None 2.67073E-05 0 None 0 0 None 0 0 8.47583E-07 3.29366E-05 0
V/A 9517 Ig-81 25 None 0.5685 None 0.999 None 0.603 0.596 0.644821044561 gnomAD-4.0.0 2.40065E-06 None None None None N None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
V/M 9517 Ig-81 25 None 0.6755 None 1.0 None 0.758 0.537 0.696542326487 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/I 9613 Ig-82 24 rs749649816 0.1153 -0.581 0.543 None 0.263 0.218 0.389439708392 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
V/I 9613 Ig-82 24 rs749649816 0.1153 -0.581 0.543 None 0.263 0.218 0.389439708392 gnomAD-4.0.0 1.59106E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85791E-06 0 0
V/F 9721 Ig-83 24 None 0.9338 None 1.0 None 0.837 0.489 0.892673261969 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
I/T 9923 Ig-84 24 None 0.9722 None 0.989 None 0.761 0.599 0.746399086789 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31252E-06 0 0
F/V 10012 Ig-85 24 None 0.9272 None 0.925 None 0.68 0.27 0.502005994047 gnomAD-4.0.0 1.36827E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79878E-06 0 0
V/L 10101 Ig-86 24 None 0.9416 None 0.997 None 0.616 0.426 0.588172243141 gnomAD-4.0.0 6.84133E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99392E-07 0 0
V/M 10101 Ig-86 24 None 0.9521 None 1.0 None 0.778 0.578 0.640176730838 gnomAD-4.0.0 6.84133E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99392E-07 0 0
V/I 13710 Ig-87 27 rs1429685157 0.1498 -0.915 0.046 D 0.205 0.161 0.507628581994 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
V/I 13710 Ig-87 27 rs1429685157 0.1498 -0.915 0.046 D 0.205 0.161 0.507628581994 gnomAD-4.0.0 3.18402E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86574E-05 0
I/T 13897 Ig-89 22 rs1288360484 0.5418 None 0.058 N 0.611 0.24 0.537125817887 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/T 13897 Ig-89 22 rs1288360484 0.5418 None 0.058 N 0.611 0.24 0.537125817887 gnomAD-4.0.0 3.75826E-06 None None None None N None 1.33837E-05 0 None 0 0 None 0 0 4.27117E-06 0 0
I/M 13988 Ig-90 24 rs745782442 0.5934 -1.346 0.999 D 0.718 0.267 0.304108284078 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/M 13988 Ig-90 24 rs745782442 0.5934 -1.346 0.999 D 0.718 0.267 0.304108284078 gnomAD-4.0.0 1.59231E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43324E-05 0
I/V 13988 Ig-90 24 None 0.4087 None 0.985 N 0.41 0.164 0.364730456448 gnomAD-4.0.0 1.59224E-06 None None None None N None 5.66444E-05 0 None 0 0 None 0 0 0 0 0
L/F 14077 Ig-91 24 rs758746920 0.7788 -1.681 0.994 N 0.761 0.338 0.582828786496 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
L/F 14077 Ig-91 24 rs758746920 0.7788 -1.681 0.994 N 0.761 0.338 0.582828786496 gnomAD-4.0.0 1.36875E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.31906E-05 0
L/P 14077 Ig-91 24 rs1325439536 0.9848 -2.189 0.998 N 0.834 0.595 0.875711544465 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
L/P 14077 Ig-91 24 rs1325439536 0.9848 -2.189 0.998 N 0.834 0.595 0.875711544465 gnomAD-4.0.0 1.59212E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85999E-06 0 0
L/V 14077 Ig-91 24 None 0.2716 None 0.122 N 0.298 0.179 0.269558022972 gnomAD-4.0.0 6.84377E-07 None None None None N None 2.9915E-05 0 None 0 0 None 0 0 0 0 0
V/E 14254 Ig-93 24 rs1342186371 0.9139 None 0.896 D 0.77 0.664 0.874471701311 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.66327E-05
L/P 14342 Ig-94 24 rs1055213360 0.9933 -2.405 0.994 N 0.901 0.44 0.522770035047 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.78E-05 0
L/P 14342 Ig-94 24 rs1055213360 0.9933 -2.405 0.994 N 0.901 0.44 0.522770035047 gnomAD-4.0.0 1.09508E-05 None None None None N None 0 0 None 0 0 None 0 0 1.43947E-05 0 0
I/L 14609 Ig-97 24 None 0.3173 None 0.005 N 0.269 0.176 0.247322355667 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
L/F 14787 Ig-99 23 None 0.7192 None 1.0 D 0.801 0.447 0.5551182358 gnomAD-4.0.0 6.84568E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99803E-07 0 0
L/I 14787 Ig-99 23 None 0.2486 None 0.999 N 0.557 0.247 0.403752378121 gnomAD-4.0.0 1.36914E-06 None None None None N None 0 0 None 0 0 None 1.87329E-05 0 8.99803E-07 0 0
V/G 14876 Ig-100 24 None 0.8129 None 0.983 D 0.845 0.71 0.933483574898 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
L/V 14965 Ig-101 24 None 0.0931 None None N 0.274 0.089 0.0551355673512 gnomAD-4.0.0 1.60816E-06 None None None None N None 0 0 None 0 0 None 0 0 2.88334E-06 0 0
V/G 15054 Ig-102 24 None 0.7464 None 0.999 D 0.856 0.75 0.874876458758 gnomAD-4.0.0 1.59419E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43345E-05 0
I/V 15143 Ig-103 24 rs778468554 0.0821 -1.316 0.001 N 0.24 0.113 0.249502417897 gnomAD-2.1.1 8.1E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 8.96E-06 0
I/V 15143 Ig-103 24 rs778468554 0.0821 -1.316 0.001 N 0.24 0.113 0.249502417897 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 15143 Ig-103 24 rs778468554 0.0821 -1.316 0.001 N 0.24 0.113 0.249502417897 gnomAD-4.0.0 3.7219E-06 None None None None N None 1.33668E-05 0 None 0 2.24417E-05 None 0 0 2.54427E-06 1.09871E-05 0
L/P 15414 Ig-106 24 None 0.9819 None 1.0 D 0.825 0.776 0.890016908248 gnomAD-4.0.0 7.16396E-07 None None None None N None 0 0 None 0 0 None 0 0 9.24618E-07 0 0
L/V 15503 Ig-107 24 None 0.3092 None 0.999 N 0.53 0.215 0.326881540566 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Y/C 15591 Ig-108 24 rs771962876 0.3894 -2.138 1.0 N 0.865 0.553 0.683444952736 gnomAD-2.1.1 1.22E-05 None None None None N None 0 0 None 0 1.69933E-04 None 0 None 0 0 0
Y/C 15591 Ig-108 24 rs771962876 0.3894 -2.138 1.0 N 0.865 0.553 0.683444952736 gnomAD-4.0.0 1.37026E-06 None None None None N None 0 0 None 0 2.53627E-05 None 0 0 9.00189E-07 0 0
Y/H 15591 Ig-108 24 rs775496863 0.7438 -2.709 1.0 N 0.746 0.574 0.545346552841 gnomAD-2.1.1 3.23E-05 None None None None N None 0 0 None 0 0 None 9.82E-05 None 0 4.73E-05 0
Y/H 15591 Ig-108 24 rs775496863 0.7438 -2.709 1.0 N 0.746 0.574 0.545346552841 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 4.79846E-04
Y/H 15591 Ig-108 24 rs775496863 0.7438 -2.709 1.0 N 0.746 0.574 0.545346552841 gnomAD-4.0.0 1.67538E-05 None None None None N None 0 0 None 0 0 None 0 5.11771E-04 1.52703E-05 3.29714E-05 4.81325E-05
S/G 15986 Ig-109 19 None 0.2667 None 0.911 N 0.561 0.168 0.301455362545 gnomAD-4.0.0 1.59334E-06 None None None None I None 0 2.28854E-05 None 0 0 None 0 0 0 0 0
S/R 15986 Ig-109 19 None 0.9379 None 0.989 N 0.772 0.308 0.320256813643 gnomAD-4.0.0 1.59334E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43324E-05 0
V/A 16282 Ig-110 21 rs878854396 0.9233 None 0.78 N 0.639 0.508 0.656149315556 gnomAD-4.0.0 1.59435E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86313E-06 0 0
V/I 16282 Ig-110 21 rs776265864 0.0991 -0.583 0.06 N 0.215 0.134 0.356484672536 gnomAD-2.1.1 5.02E-05 None None None None I None 8.28E-05 0 None 0 4.17014E-04 None 0 None 0 3.14E-05 0
V/I 16282 Ig-110 21 rs776265864 0.0991 -0.583 0.06 N 0.215 0.134 0.356484672536 gnomAD-3.1.2 6.58E-05 None None None None I None 2.42E-05 6.57E-05 0 0 9.758E-04 None 0 0 4.42E-05 0 0
V/I 16282 Ig-110 21 rs776265864 0.0991 -0.583 0.06 N 0.215 0.134 0.356484672536 gnomAD-4.0.0 4.59015E-05 None None None None I None 5.34802E-05 1.67101E-05 None 0 2.01902E-04 None 0 1.64799E-04 4.9191E-05 0 1.60375E-05
F/C 16978 Ig-111 24 rs1173795392 0.6074 -1.915 1.0 D 0.869 0.489 0.796794439838 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
F/C 16978 Ig-111 24 rs1173795392 0.6074 -1.915 1.0 D 0.869 0.489 0.796794439838 gnomAD-4.0.0 1.59343E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86164E-06 0 0
F/L 16978 Ig-111 24 rs1417308681 0.9637 None 0.999 N 0.617 0.558 0.448498829774 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
F/L 16978 Ig-111 24 rs1417308681 0.9637 None 0.999 N 0.617 0.558 0.448498829774 gnomAD-4.0.0 3.84847E-06 None None None None N None 0 0 None 0 0 None 0 0 7.18752E-06 0 0
F/Y 16978 Ig-111 24 rs1173795392 0.2209 -1.329 0.999 N 0.57 0.286 0.558264529485 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.64E-05 None 0 None 0 0 0
F/Y 16978 Ig-111 24 rs1173795392 0.2209 -1.329 0.999 N 0.57 0.286 0.558264529485 gnomAD-4.0.0 1.59343E-06 None None None None N None 0 0 None 0 2.78909E-05 None 0 0 0 0 0
I/T 17271 Ig-112 21 rs764070559 0.9096 -1.76 0.124 N 0.753 0.47 0.683701784845 gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.79E-05 0
I/T 17271 Ig-112 21 rs764070559 0.9096 -1.76 0.124 N 0.753 0.47 0.683701784845 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
I/T 17271 Ig-112 21 rs764070559 0.9096 -1.76 0.124 N 0.753 0.47 0.683701784845 gnomAD-4.0.0 8.06244E-06 None None None None I None 1.33679E-05 0 None 0 0 None 0 0 8.48067E-06 0 3.20616E-05
I/V 17271 Ig-112 21 rs754159960 0.0876 -0.907 None N 0.258 0.052 0.356072328145 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 3.28E-05 None 0 0 0
I/V 17271 Ig-112 21 rs754159960 0.0876 -0.907 None N 0.258 0.052 0.356072328145 gnomAD-4.0.0 1.59387E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.4346E-05 0
V/A 17696 Ig-113 20 rs764155048 0.868 -0.621 0.999 N 0.615 0.615 0.670712675582 gnomAD-4.0.0 3.18507E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.8659E-05 0
V/G 17696 Ig-113 20 None 0.9398 None 1.0 D 0.823 0.759 0.863498451129 gnomAD-4.0.0 1.59253E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43295E-05 0
V/L 17696 Ig-113 20 None 0.6849 None 0.997 D 0.668 0.506 0.726976991548 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
V/A 17990 Ig-114 23 None 0.8911 None 0.977 N 0.609 0.647 0.723663604452 gnomAD-4.0.0 3.60103E-06 None None None None N None 0 0 None 0 0 None 0 0 3.93757E-06 0 0
I/L 18402 Ig-115 21 None 0.2048 None 0.993 N 0.43 0.453 0.618312362157 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/N 18402 Ig-115 21 rs776899398 0.944 -0.193 1.0 N 0.844 0.686 0.903074480649 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
I/N 18402 Ig-115 21 rs776899398 0.944 -0.193 1.0 N 0.844 0.686 0.903074480649 gnomAD-4.0.0 6.84591E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99847E-07 0 0
I/S 18402 Ig-115 21 rs776899398 0.9372 -0.708 1.0 N 0.813 0.643 0.904873369186 gnomAD-2.1.1 4.84E-05 None None None None I None 0 2.90309E-04 None 0 0 None 0 None 0 1.78E-05 0
I/S 18402 Ig-115 21 rs776899398 0.9372 -0.708 1.0 N 0.813 0.643 0.904873369186 gnomAD-3.1.2 1.64573E-04 None None None None I None 0 1.50978E-03 0 0 0 None 0 0 2.94E-05 0 0
I/S 18402 Ig-115 21 rs776899398 0.9372 -0.708 1.0 N 0.813 0.643 0.904873369186 gnomAD-4.0.0 3.10052E-05 None None None None I None 0 5.34135E-04 None 0 0 None 0 0 1.44162E-05 0 1.60251E-05
I/T 18708 Ig-116 21 None 0.9109 None 0.505 N 0.661 0.517 0.685061634186 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
V/M 19116 Ig-117 22 rs2052100792 0.4686 None 1.0 D 0.774 0.525 0.805721141949 gnomAD-3.1.2 6.58E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
V/M 19116 Ig-117 22 rs2052100792 0.4686 None 1.0 D 0.774 0.525 0.805721141949 gnomAD-4.0.0 6.57765E-06 None None None None I None 0 6.55222E-05 None 0 0 None 0 0 0 0 0
I/S 19810 Ig-119 21 None 0.9747 None 0.998 D 0.816 0.658 0.865813452579 gnomAD-4.0.0 1.59192E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85948E-06 0 0
I/V 19810 Ig-119 21 None 0.1878 None 0.333 N 0.188 0.173 0.485493271093 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
I/L 20102 Ig-120 23 rs755647048 0.1336 -0.428 0.007 D 0.277 0.208 0.539792608675 gnomAD-2.1.1 4.12E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.05E-06 0
I/L 20102 Ig-120 23 rs755647048 0.1336 -0.428 0.007 D 0.277 0.208 0.539792608675 gnomAD-4.0.0 6.86685E-07 None None None None N None 0 0 None 0 0 None 0 0 9.01326E-07 0 0
I/M 20102 Ig-120 23 None 0.1091 None 0.001 N 0.225 0.109 0.421184727016 gnomAD-4.0.0 1.60376E-06 None None None None N None 0 0 None 0 2.7767E-05 None 0 0 0 0 0
I/T 20102 Ig-120 23 rs998020901 0.7537 -1.961 0.183 D 0.616 0.443 0.703810458386 gnomAD-2.1.1 4.11E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.05E-06 0
I/T 20102 Ig-120 23 rs998020901 0.7537 -1.961 0.183 D 0.616 0.443 0.703810458386 gnomAD-4.0.0 1.60437E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87704E-06 0 0
I/V 20102 Ig-120 23 rs755647048 0.1241 -0.931 0.001 N 0.194 0.119 0.494433119893 gnomAD-2.1.1 4.12E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.05E-06 0
I/V 20102 Ig-120 23 rs755647048 0.1241 -0.931 0.001 N 0.194 0.119 0.494433119893 gnomAD-4.0.0 5.49348E-06 None None None None N None 0 0 None 0 0 None 0 0 6.30928E-06 0 1.66262E-05
V/L 20500 Ig-121 22 None 0.6832 None 0.369 D 0.545 0.44 0.546521485473 gnomAD-4.0.0 1.63546E-06 None None None None N None 0 0 None 0 0 None 0 0 2.92754E-06 0 0
V/I 20793 Ig-122 25 None 0.068 None 0.454 N 0.613 0.175 0.502752565406 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
V/A 21198 Ig-123 22 None 0.6278 None 0.78 N 0.648 0.496 0.699911873028 gnomAD-4.0.0 1.59332E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43406E-05 0
V/G 21198 Ig-123 22 rs1559553614 0.7551 None 0.995 D 0.837 0.653 0.88472872791 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.92E-06 0
V/G 21198 Ig-123 22 rs1559553614 0.7551 None 0.995 D 0.837 0.653 0.88472872791 gnomAD-4.0.0 1.59332E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86125E-06 0 0
V/L 21198 Ig-123 22 None 0.345 None 0.437 D 0.461 0.36 0.552085806491 gnomAD-4.0.0 6.84584E-07 None None None None I None 0 0 None 0 0 None 1.8742E-05 0 0 0 0
V/M 21198 Ig-123 22 None 0.3968 None 0.968 D 0.704 0.596 0.69131558434 gnomAD-4.0.0 6.84584E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99769E-07 0 0
V/A 21490 Ig-124 22 None 0.6948 None 0.999 N 0.614 0.579 0.70308399845 gnomAD-4.0.0 1.59329E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.0259E-05
V/L 21490 Ig-124 22 rs138858121 0.3511 -0.792 0.997 D 0.635 0.498 0.692415691238 gnomAD-2.1.1 8.06E-06 None None None None N None 0 0 None 0 1.11669E-04 None 0 None 0 0 0
V/L 21490 Ig-124 22 rs138858121 0.3511 -0.792 0.997 D 0.635 0.498 0.692415691238 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.94175E-04 None 0 0 0 0 0
V/L 21490 Ig-124 22 rs138858121 0.3511 -0.792 0.997 D 0.635 0.498 0.692415691238 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
V/L 21490 Ig-124 22 rs138858121 0.3511 -0.792 0.997 D 0.635 0.498 0.692415691238 gnomAD-4.0.0 3.84789E-06 None None None None N None 0 0 None 0 4.85814E-05 None 0 0 0 0 2.84446E-05
V/I 21887 Ig-125 22 None 0.0978 None 0.767 N 0.25 0.244 0.556581311739 gnomAD-4.0.0 3.18865E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72659E-06 0 0
V/I 22285 Ig-126 21 None 0.1061 None 0.248 N 0.303 0.141 0.414798848334 gnomAD-4.0.0 6.84633E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99815E-07 0 0
V/L 22285 Ig-126 21 rs754121833 0.5053 -0.467 0.031 D 0.27 0.244 0.45746916685 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.93E-06 0
V/L 22285 Ig-126 21 rs754121833 0.5053 -0.467 0.031 D 0.27 0.244 0.45746916685 gnomAD-4.0.0 6.84633E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99815E-07 0 0
I/M 22574 Ig-127 15 None 0.1745 None 0.267 N 0.315 0.24 0.236890367714 gnomAD-4.0.0 6.85482E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00812E-07 0 0
I/V 22574 Ig-127 15 rs754723277 0.0801 -1.115 0.022 N 0.209 0.08 0.349204839081 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.91E-06 0
I/V 22574 Ig-127 15 rs754723277 0.0801 -1.115 0.022 N 0.209 0.08 0.349204839081 gnomAD-4.0.0 3.19679E-06 None None None None I None 0 0 None 0 0 None 0 0 2.87221E-06 1.43579E-05 0
I/F 22971 Ig-128 22 rs1335554435 0.5237 -1.431 1.0 N 0.808 0.604 0.581565680727 gnomAD-2.1.1 4.04E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
I/F 22971 Ig-128 22 rs1335554435 0.5237 -1.431 1.0 N 0.808 0.604 0.581565680727 gnomAD-4.0.0 3.19523E-06 None None None None N None 0 2.28833E-05 None 0 0 None 0 0 2.86937E-06 0 0
I/N 23368 Ig-129 24 None 0.9694 None 1.0 N 0.859 0.698 0.90350922459 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/V 23368 Ig-129 24 rs367914610 0.0977 -1.415 0.993 N 0.353 0.25 None gnomAD-2.1.1 9.65E-05 None None None None N None 4.13E-05 0 None 0 0 None 1.30779E-04 None 0 1.56345E-04 2.81057E-04
I/V 23368 Ig-129 24 rs367914610 0.0977 -1.415 0.993 N 0.353 0.25 None gnomAD-3.1.2 5.26E-05 None None None None N None 0 1.96515E-04 0 0 0 None 0 0 4.41E-05 0 9.5511E-04
I/V 23368 Ig-129 24 rs367914610 0.0977 -1.415 0.993 N 0.353 0.25 None gnomAD-4.0.0 8.98834E-05 None None None None N None 8.01089E-05 8.33611E-05 None 0 0 None 0 1.811E-03 7.88494E-05 1.2081E-04 3.04273E-04
V/A 23657 Ig-130 21 rs754468593 0.6768 -1.651 0.999 N 0.598 0.637 0.721090787401 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.97E-06 0
V/A 23657 Ig-130 21 rs754468593 0.6768 -1.651 0.999 N 0.598 0.637 0.721090787401 gnomAD-4.0.0 3.42342E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49903E-06 0 0
V/G 23657 Ig-130 21 rs754468593 0.8304 -2.245 1.0 D 0.82 0.76 0.88305327775 gnomAD-2.1.1 4.06E-06 None None None None I None 0 2.92E-05 None 0 0 None 0 None 0 0 0
V/G 23657 Ig-130 21 rs754468593 0.8304 -2.245 1.0 D 0.82 0.76 0.88305327775 gnomAD-4.0.0 6.84684E-07 None None None None I None 0 2.24044E-05 None 0 0 None 0 0 0 0 0
V/L 23657 Ig-130 21 None 0.2516 None 0.997 D 0.621 0.505 0.744215552228 gnomAD-4.0.0 6.84679E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.16104E-05 0
V/M 23657 Ig-130 21 rs752876499 0.2762 -0.634 1.0 D 0.74 0.6 0.784675601237 gnomAD-2.1.1 8.11E-06 None None None None I None 0 0 None 0 0 None 6.58E-05 None 0 0 0
V/M 23657 Ig-130 21 rs752876499 0.2762 -0.634 1.0 D 0.74 0.6 0.784675601237 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07469E-04 0
V/M 23657 Ig-130 21 rs752876499 0.2762 -0.634 1.0 D 0.74 0.6 0.784675601237 gnomAD-4.0.0 1.86035E-06 None None None None I None 0 0 None 0 0 None 0 0 0 3.29852E-05 0
V/D 24053 Ig-131 25 None 0.9924 None 1.0 D 0.844 0.875 0.922313786736 gnomAD-4.0.0 1.59221E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85948E-06 0 0
I/V 24452 Ig-132 22 rs1708703348 0.0928 None 0.011 N 0.229 0.082 0.312001716656 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
F/L 24739 Ig-133 24 None 0.9237 None 0.309 N 0.583 0.332 0.298056030225 gnomAD-4.0.0 1.59234E-06 None None None None N None 0 2.28749E-05 None 0 0 None 0 0 0 0 0
I/L 25534 Ig-135 21 rs1245433477 0.2065 None 0.164 D 0.446 0.209 0.338592109245 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.62E-05 None 0 None 0 0 0
I/L 25534 Ig-135 21 rs1245433477 0.2065 None 0.164 D 0.446 0.209 0.338592109245 gnomAD-4.0.0 6.84689E-07 None None None None N None 0 0 None 0 2.52717E-05 None 0 0 0 0 0
I/V 25534 Ig-135 21 rs1245433477 0.0892 -1.394 0.012 N 0.221 0.06 0.311691414656 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
I/V 25534 Ig-135 21 rs1245433477 0.0892 -1.394 0.012 N 0.221 0.06 0.311691414656 gnomAD-4.0.0 6.84689E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99831E-07 0 0
I/L 25821 Ig-136 24 None 0.1454 None 0.084 N 0.49 0.149 0.312306559268 gnomAD-4.0.0 1.59212E-06 None None None None N None 5.66059E-05 0 None 0 0 None 0 0 0 0 0
V/A 26217 Ig-137 25 rs748869015 0.8712 -2.4 0.998 N 0.659 0.64 0.633262315121 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.28E-05 None 0 0 0
V/A 26217 Ig-137 25 rs748869015 0.8712 -2.4 0.998 N 0.659 0.64 0.633262315121 gnomAD-4.0.0 1.59286E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43497E-05 0
F/L 26616 Ig-138 23 rs1705818116 0.966 None 0.369 N 0.601 0.421 0.274366138417 gnomAD-4.0.0 1.20034E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07681E-05 0
V/I 26903 Ig-139 24 rs1559341049 0.076 None None N 0.289 0.151 0.409533910539 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.66058E-04
V/I 26903 Ig-139 24 rs1559341049 0.076 None None N 0.289 0.151 0.409533910539 gnomAD-4.0.0 4.79048E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49788E-06 1.15982E-05 1.65733E-05
I/N 27699 Ig-141 24 None 0.9799 None 0.994 D 0.806 0.643 0.899465142518 gnomAD-4.0.0 6.84242E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9952E-07 0 0
I/T 27699 Ig-141 24 rs1411163896 0.9272 -2.383 0.892 N 0.726 0.553 0.760912148185 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
I/T 27699 Ig-141 24 rs1411163896 0.9272 -2.383 0.892 N 0.726 0.553 0.760912148185 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/T 27699 Ig-141 24 rs1411163896 0.9272 -2.383 0.892 N 0.726 0.553 0.760912148185 gnomAD-4.0.0 1.85927E-06 None None None None N None 4.00598E-05 0 None 0 0 None 0 0 0 0 0
I/V 27699 Ig-141 24 None 0.1212 None 0.011 N 0.201 0.154 0.443592365053 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
F/L 27986 Ig-142 24 rs1184136352 0.8482 -1.774 0.027 N 0.603 0.195 0.257786959452 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.95E-06 0
F/V 28778 Ig-144 24 None 0.5425 None 0.805 N 0.735 0.355 0.53832913131 gnomAD-4.0.0 1.37279E-06 None None None None I None 0 0 None 0 0 None 0 0 1.80095E-06 0 0
I/V 29068 Ig-145 24 rs766759385 0.064 -1.675 0.005 N 0.205 0.067 0.288352970974 gnomAD-2.1.1 1.24939E-04 None None None None N None 0 0 None 0 0 None 9.80777E-04 None 0 0 1.66334E-04
I/V 29068 Ig-145 24 rs766759385 0.064 -1.675 0.005 N 0.205 0.067 0.288352970974 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 2.06954E-04 0
I/V 29068 Ig-145 24 rs766759385 0.064 -1.675 0.005 N 0.205 0.067 0.288352970974 gnomAD-4.0.0 5.0814E-05 None None None None N None 0 0 None 0 0 None 0 1.64528E-04 5.933E-06 7.79483E-04 4.80292E-05
I/L 29464 Ig-146 21 rs1700847616 0.2695 None 0.993 D 0.413 0.462 0.687289144923 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 9.42E-05 0 0 0 0
I/L 29464 Ig-146 21 rs1700847616 0.2695 None 0.993 D 0.413 0.462 0.687289144923 gnomAD-4.0.0 6.57091E-06 None None None None N None 0 0 None 0 0 None 9.4162E-05 0 0 0 0
F/S 29863 Ig-147 22 None 0.9616 None 0.998 N 0.805 0.6 0.746065682744 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
Y/C 30155 Ig-148 24 rs918516226 0.2016 -1.486 1.0 D 0.754 0.374 0.442977140156 gnomAD-2.1.1 4.09E-06 None None None None N None 6.47E-05 0 None 0 0 None 0 None 0 0 0
Y/C 30155 Ig-148 24 rs918516226 0.2016 -1.486 1.0 D 0.754 0.374 0.442977140156 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
Y/C 30155 Ig-148 24 rs918516226 0.2016 -1.486 1.0 D 0.754 0.374 0.442977140156 gnomAD-4.0.0 1.87219E-06 None None None None N None 1.33829E-05 0 None 0 0 None 0 0 8.53477E-07 0 1.61457E-05
Y/H 30155 Ig-148 24 None 0.7364 None 0.999 N 0.707 0.533 0.402326594622 gnomAD-4.0.0 2.40066E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 1.31251E-06 0 0
V/I 30550 Ig-149 19 None 0.0819 None 0.001 N 0.27 0.196 0.392395365052 gnomAD-4.0.0 1.59137E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43287E-05 0
I/N 31239 Ig-151 22 None 0.9535 None 0.999 D 0.833 0.685 0.819228050113 gnomAD-4.0.0 1.36838E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79887E-06 0 0
I/V 31239 Ig-151 22 None 0.075 None 0.941 N 0.457 0.163 0.400468435593 gnomAD-4.0.0 2.40065E-06 None None None None I None 0 0 None 0 0 None 0 0 2.62501E-06 0 0
V/A 31639 Ig-152 19 rs759136839 0.4728 -1.733 0.939 N 0.59 0.581 0.57068417637 gnomAD-2.1.1 4.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
V/A 31639 Ig-152 19 rs759136839 0.4728 -1.733 0.939 N 0.59 0.581 0.57068417637 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 2.75482E-04 None 0 0 0 0 0
V/A 32038 Ig-153 22 rs1274429401 0.6198 -1.809 0.999 N 0.627 0.613 0.73768680617 gnomAD-2.1.1 1.21E-05 None None None None N None 0 8.69E-05 None 0 0 None 0 None 0 0 0
V/A 32038 Ig-153 22 rs1274429401 0.6198 -1.809 0.999 N 0.627 0.613 0.73768680617 gnomAD-4.0.0 6.3662E-06 None None None None N None 0 9.1462E-05 None 0 0 None 0 0 0 0 0
V/I 32038 Ig-153 22 rs753330318 0.0895 -0.782 0.997 N 0.576 0.316 None gnomAD-2.1.1 1.21E-05 None None None None N None 1.93748E-04 0 None 0 0 None 0 None 0 0 0
V/I 32038 Ig-153 22 rs753330318 0.0895 -0.782 0.997 N 0.576 0.316 None gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
V/I 32038 Ig-153 22 rs753330318 0.0895 -0.782 0.997 N 0.576 0.316 None gnomAD-4.0.0 1.85928E-06 None None None None N None 4.00662E-05 0 None 0 0 None 0 0 0 0 0
I/L 32330 Ig-154 24 None 0.1507 None 0.817 N 0.512 0.26 0.519837540645 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.07533E-05 0
I/T 32330 Ig-154 24 rs201023432 0.4889 -2.365 0.98 N 0.757 0.605 None gnomAD-2.1.1 5.73E-05 None None None None N None 0 2.83E-05 None 0 0 None 0 None 0 1.18092E-04 0
I/T 32330 Ig-154 24 rs201023432 0.4889 -2.365 0.98 N 0.757 0.605 None gnomAD-3.1.2 8.54E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 1.61703E-04 0 0
I/T 32330 Ig-154 24 rs201023432 0.4889 -2.365 0.98 N 0.757 0.605 None gnomAD-4.0.0 2.20611E-04 None None None None N None 4.00416E-05 1.667E-05 None 0 0 None 0 0 2.86492E-04 2.19602E-05 1.92117E-04
I/N 32728 Ig-155 21 rs764737796 0.945 -1.102 0.975 N 0.785 0.622 0.843158877575 gnomAD-2.1.1 1.07E-05 None None None None I None 0 0 None 0 0 None 0 None 0 2.34E-05 0
I/N 32728 Ig-155 21 rs764737796 0.945 -1.102 0.975 N 0.785 0.622 0.843158877575 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
I/N 32728 Ig-155 21 rs764737796 0.945 -1.102 0.975 N 0.785 0.622 0.843158877575 gnomAD-4.0.0 3.84425E-06 None None None None I None 0 0 None 0 0 None 0 0 7.17964E-06 0 0
I/V 32728 Ig-155 21 None 0.0795 None 0.002 N 0.23 0.083 0.293502639404 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
I/T 33124 Ig-156 24 rs1460988809 0.8805 -3.047 1.0 D 0.777 0.601 0.785110947316 gnomAD-2.1.1 4.02E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 0 0
I/T 33124 Ig-156 24 rs1460988809 0.8805 -3.047 1.0 D 0.777 0.601 0.785110947316 gnomAD-4.0.0 2.73708E-06 None None None None N None 5.978E-05 0 None 0 0 None 0 0 1.79901E-06 0 0
Y/C 33220 Ig-157 18 None 0.6484 None 1.0 N 0.697 0.558 0.61844985043 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
Y/H 33220 Ig-157 18 rs776277442 0.8997 -3.152 1.0 N 0.747 0.55 0.504175077286 gnomAD-4.0.0 1.11401E-05 None None None None N None 0 0 None 0 1.94175E-04 None 0 0 0 0 0
V/L 33519 Ig-158 24 None 0.7915 None 0.381 D 0.673 0.378 0.485493271093 gnomAD-4.0.0 1.36873E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79922E-06 0 0
V/M 33519 Ig-158 24 None 0.7963 None 0.994 D 0.727 0.548 0.688093782497 gnomAD-4.0.0 6.84367E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99609E-07 0 0
I/T 34159 Ig-160 23 rs1690397017 0.8434 None 0.999 D 0.779 0.743 0.800328269811 gnomAD-4.0.0 1.59095E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85765E-06 0 0
I/L 34281 Ig-161 24 rs758945559 0.4123 -0.914 0.973 N 0.441 0.378 0.636570122401 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.85E-06 0
I/L 34281 Ig-161 24 rs758945559 0.4123 -0.914 0.973 N 0.441 0.378 0.636570122401 gnomAD-4.0.0 4.78906E-06 None None None None N None 0 0 None 0 0 None 0 0 6.29587E-06 0 0
I/M 34281 Ig-161 24 None 0.3797 None 0.999 N 0.719 0.417 0.642701035604 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
I/R 34281 Ig-161 24 rs779369864 0.9928 -1.424 0.998 N 0.851 0.817 0.878042342013 gnomAD-2.1.1 4.01E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/R 34281 Ig-161 24 rs779369864 0.9928 -1.424 0.998 N 0.851 0.817 0.878042342013 gnomAD-4.0.0 1.36831E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.15931E-05 1.6564E-05
I/T 34281 Ig-161 24 rs779369864 0.9593 -2.721 0.543 N 0.447 0.54 0.700574847502 gnomAD-2.1.1 3.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 7.08E-05 0
I/T 34281 Ig-161 24 rs779369864 0.9593 -2.721 0.543 N 0.447 0.54 0.700574847502 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
I/T 34281 Ig-161 24 rs779369864 0.9593 -2.721 0.543 N 0.447 0.54 0.700574847502 gnomAD-4.0.0 1.05337E-05 None None None None N None 0 0 None 0 0 None 0 0 1.44082E-05 0 0
I/V 34281 Ig-161 24 rs758945559 0.1176 -1.444 0.941 N 0.413 0.261 0.448794319169 gnomAD-2.1.1 8.03E-06 None None None None N None 6.46E-05 0 None 0 0 None 0 None 0 8.85E-06 0
I/V 34281 Ig-161 24 rs758945559 0.1176 -1.444 0.941 N 0.413 0.261 0.448794319169 gnomAD-3.1.2 6.57E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
I/V 34281 Ig-161 24 rs758945559 0.1176 -1.444 0.941 N 0.413 0.261 0.448794319169 gnomAD-4.0.0 1.85885E-06 None None None None N None 1.33451E-05 0 None 0 0 None 0 0 8.47541E-07 1.09779E-05 0
V/A 34386 Ig-162 24 rs1407044012 0.9212 -2.721 0.999 N 0.623 0.676 0.663921437314 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.88E-06 0
V/A 34386 Ig-162 24 rs1407044012 0.9212 -2.721 0.999 N 0.623 0.676 0.663921437314 gnomAD-4.0.0 6.84275E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9957E-07 0 0
V/E 34386 Ig-162 24 None 0.9955 None 1.0 D 0.865 0.876 0.875711544465 gnomAD-4.0.0 6.84275E-07 None None None None N None 0 0 None 0 0 None 0 0 8.9957E-07 0 0
V/M 34386 Ig-162 24 rs763989580 0.8962 -0.97 1.0 D 0.757 0.646 0.682792094187 gnomAD-2.1.1 1.61E-05 None None None None N None 0 0 None 0 0 None 0 None 0 3.55E-05 0
V/M 34386 Ig-162 24 rs763989580 0.8962 -0.97 1.0 D 0.757 0.646 0.682792094187 gnomAD-3.1.2 1.31E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
V/M 34386 Ig-162 24 rs763989580 0.8962 -0.97 1.0 D 0.757 0.646 0.682792094187 gnomAD-4.0.0 6.1973E-06 None None None None N None 0 0 None 0 0 None 0 0 7.62916E-06 1.09786E-05 0
V/I 34965 Ig-163 24 None 0.1423 None 0.767 D 0.262 0.247 0.551838628669 gnomAD-4.0.0 1.36828E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7988E-06 0 0
V/L 34965 Ig-163 24 rs886042785 0.7633 -0.858 0.981 D 0.645 0.43 0.590433232774 gnomAD-2.1.1 1.07E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.34E-05 0
V/L 34965 Ig-163 24 rs886042785 0.7633 -0.858 0.981 D 0.645 0.43 0.590433232774 gnomAD-3.1.2 4.6E-05 None None None None N None 0 0 4.38597E-03 0 0 None 0 0 4.41E-05 0 0
V/L 34965 Ig-163 24 rs886042785 0.7633 -0.858 0.981 D 0.645 0.43 0.590433232774 gnomAD-4.0.0 7.43553E-06 None None None None N None 0 0 None 0 0 None 0 0 5.93277E-06 0 1.60082E-05
T/I 35152 Ig-164 24 None 0.2545 None 0.002 N 0.402 0.189 0.245660935333 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/N 35152 Ig-164 24 None 0.6801 None 0.917 D 0.647 0.267 0.446310458034 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
T/P 35152 Ig-164 24 rs772336949 0.7198 -2.058 0.784 N 0.729 0.321 0.385417323374 gnomAD-2.1.1 1.2E-05 None None None None N None 0 0 None 0 0 None 9.8E-05 None 0 0 0
T/P 35152 Ig-164 24 rs772336949 0.7198 -2.058 0.784 N 0.729 0.321 0.385417323374 gnomAD-4.0.0 4.10482E-06 None None None None N None 0 0 None 0 0 None 0 0 0 6.95588E-05 0
V/A 35307 Ig-165 22 rs780629996 0.1726 -2.259 0.025 N 0.341 0.327 0.531629458225 gnomAD-2.1.1 9.64E-05 None None None None N None 0 6.0866E-04 None 0 0 None 0 None 0 1.77E-05 1.65563E-04
V/A 35307 Ig-165 22 rs780629996 0.1726 -2.259 0.025 N 0.341 0.327 0.531629458225 gnomAD-3.1.2 1.77494E-04 None None None None N None 0 1.70224E-03 0 0 0 None 0 0 1.47E-05 0 0
V/A 35307 Ig-165 22 rs780629996 0.1726 -2.259 0.025 N 0.341 0.327 0.531629458225 gnomAD-4.0.0 5.20511E-05 None None None None N None 0 9.33427E-04 None 0 0 None 0 0 2.11886E-05 1.09794E-05 3.20174E-05
A/G 35443 Ig-166 24 None 0.2335 None 0.094 N 0.645 0.237 0.201204373187 gnomAD-4.0.0 3.60097E-06 None None None None N None 0 0 None 0 0 None 0 0 3.9375E-06 0 0
A/T 35443 Ig-166 24 rs1369230756 0.1566 -1.176 0.011 N 0.601 0.138 0.296329037015 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
A/T 35443 Ig-166 24 rs1369230756 0.1566 -1.176 0.011 N 0.601 0.138 0.296329037015 gnomAD-4.0.0 1.5929E-06 None None None None N None 0 2.28749E-05 None 0 0 None 0 0 0 0 0
I/V 35630 Ig-167 24 rs754830278 0.132 -0.804 0.19 N 0.498 0.094 0.314716216878 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
I/V 35630 Ig-167 24 rs754830278 0.132 -0.804 0.19 N 0.498 0.094 0.314716216878 gnomAD-4.0.0 1.5909E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
I/V 35725 Ig-168 24 rs1687594887 0.1234 None None N 0.215 0.15 0.199424873507 gnomAD-4.0.0 3.18728E-06 None None None None N None 5.66123E-05 0 None 0 0 None 0 0 2.86226E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.