Structural position:

  • Domain Type: Ig
  • Aligned Position: 42
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
P/L 131 Ig-2 28 rs781001961 0.8817 -0.417 1.0 D 0.757 0.659 0.890570975953 gnomAD-2.1.1 3.98E-06 None None None -0.645(TCAP) N None 6.15E-05 0 None 0 0 None 0 None 0 0 0
P/L 131 Ig-2 28 rs781001961 0.8817 -0.417 1.0 D 0.757 0.659 0.890570975953 gnomAD-3.1.2 1.97E-05 None None None -0.645(TCAP) N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
P/L 131 Ig-2 28 rs781001961 0.8817 -0.417 1.0 D 0.757 0.659 0.890570975953 gnomAD-4.0.0 1.97114E-05 None None None -0.645(TCAP) N None 7.23798E-05 0 None 0 0 None 0 0 0 0 0
P/S 131 Ig-2 28 rs747867752 0.8712 -1.096 1.0 D 0.747 0.718 0.606623169391 gnomAD-2.1.1 1.19E-05 None None None -0.279(TCAP) N None 0 0 None 0 0 None 9.81E-05 None 0 0 0
P/S 131 Ig-2 28 rs747867752 0.8712 -1.096 1.0 D 0.747 0.718 0.606623169391 gnomAD-3.1.2 6.57E-06 None None None -0.279(TCAP) N None 0 0 0 0 0 None 0 0 0 2.07211E-04 0
P/S 131 Ig-2 28 rs747867752 0.8712 -1.096 1.0 D 0.747 0.718 0.606623169391 gnomAD-4.0.0 6.19567E-06 None None None -0.279(TCAP) N None 0 0 None 0 0 None 0 0 0 1.09823E-04 0
P/A 970 Ig-3 28 rs771852108 0.9297 -0.59 1.0 D 0.769 0.537 0.620928753958 gnomAD-2.1.1 1.99E-05 None None None None I None 0 0 None 0 2.7245E-04 None 0 None 0 0 0
P/A 970 Ig-3 28 rs771852108 0.9297 -0.59 1.0 D 0.769 0.537 0.620928753958 gnomAD-4.0.0 1.27245E-05 None None None None I None 0 0 None 0 2.21902E-04 None 0 0 0 0 0
P/L 970 Ig-3 28 rs745978235 0.9458 -0.257 1.0 D 0.803 0.59 0.893290774992 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.83E-06 0
P/S 1109 Ig-4 28 rs375285782 0.9806 -0.395 1.0 D 0.724 0.732 None gnomAD-2.1.1 3.98E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.82E-06 0
P/S 1109 Ig-4 28 rs375285782 0.9806 -0.395 1.0 D 0.724 0.732 None gnomAD-4.0.0 6.84072E-06 None None None None I None 0 0 None 0 0 None 0 0 8.993E-06 0 0
P/A 1318 Ig-5 28 None 0.9371 None 1.0 D 0.724 0.831 0.63026181922 gnomAD-4.0.0 6.84307E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65601E-05
P/S 1318 Ig-5 28 rs879048673 0.9821 None 1.0 D 0.746 0.834 None gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 1318 Ig-5 28 rs879048673 0.9821 None 1.0 D 0.746 0.834 None gnomAD-4.0.0 6.57358E-06 None None None None I None 2.41441E-05 0 None 0 0 None 0 0 0 0 0
P/L 1484 Ig-6 28 rs2092381354 0.9848 None 1.0 D 0.784 0.723 0.890216517135 gnomAD-4.0.0 1.36824E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79866E-06 0 0
P/R 1484 Ig-6 28 None 0.9882 None 1.0 D 0.807 0.799 0.809028025951 gnomAD-4.0.0 6.84119E-07 None None None None I None 2.98829E-05 0 None 0 0 None 0 0 0 0 0
P/T 1484 Ig-6 28 rs1275579483 0.984 None 1.0 D 0.769 0.74 0.755714991105 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 1484 Ig-6 28 rs1275579483 0.984 None 1.0 D 0.769 0.74 0.755714991105 gnomAD-4.0.0 6.57194E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46972E-05 0 0
P/H 1583 Ig-7 28 rs2092326705 0.9831 None 1.0 D 0.784 0.739 0.71266998192 gnomAD-4.0.0 1.59063E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85673E-06 0 0
P/S 1583 Ig-7 28 rs1023231093 0.9739 None 1.0 D 0.755 0.741 0.640766565566 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 1583 Ig-7 28 rs1023231093 0.9739 None 1.0 D 0.755 0.741 0.640766565566 gnomAD-4.0.0 2.02997E-06 None None None None I None 0 0 None 0 0 None 0 0 2.40987E-06 0 0
P/T 1583 Ig-7 28 None 0.9297 -0.346 1.0 D 0.751 0.762 0.683407299014 gnomAD-2.1.1 3.19E-05 None None None None I None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
P/T 1583 Ig-7 28 None 0.9297 -0.346 1.0 D 0.751 0.762 0.683407299014 gnomAD-3.1.2 1.31E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/T 1583 Ig-7 28 None 0.9297 -0.346 1.0 D 0.751 0.762 0.683407299014 gnomAD-4.0.0 3.04495E-06 None None None None I None 3.49724E-05 0 None 0 0 None 0 0 1.20493E-06 0 0
P/S 1732 Ig-8 30 rs1375104988 0.7571 -0.127 1.0 D 0.749 0.742 0.606545613963 gnomAD-2.1.1 3.18E-05 None None None None I None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
P/S 1732 Ig-8 30 rs1375104988 0.7571 -0.127 1.0 D 0.749 0.742 0.606545613963 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 1732 Ig-8 30 rs1375104988 0.7571 -0.127 1.0 D 0.749 0.742 0.606545613963 gnomAD-4.0.0 6.57082E-06 None None None None I None 2.41231E-05 0 None 0 0 None 0 0 0 0 0
P/H 1868 Ig-9 28 None 0.9934 -0.954 1.0 D 0.801 0.62 0.544432747571 gnomAD-2.1.1 3.98E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.8E-06 0
P/H 1868 Ig-9 28 None 0.9934 -0.954 1.0 D 0.801 0.62 0.544432747571 gnomAD-4.0.0 1.5906E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85659E-06 0 0
P/L 1868 Ig-9 28 rs773566945 0.971 None 1.0 D 0.769 0.569 0.702021384705 gnomAD-4.0.0 1.5906E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85659E-06 0 0
P/R 1868 Ig-9 28 rs773566945 0.9862 -0.382 1.0 D 0.801 0.639 0.540879910095 gnomAD-2.1.1 3.98E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.8E-06 0
P/R 1868 Ig-9 28 rs773566945 0.9862 -0.382 1.0 D 0.801 0.639 0.540879910095 gnomAD-4.0.0 1.5906E-06 None None None None I None 0 0 None 0 2.77254E-05 None 0 0 0 0 0
P/R 2105 Ig-10 28 rs547169244 0.9882 -0.529 1.0 D 0.772 0.816 0.694656268378 gnomAD-2.1.1 1.99E-05 None None None None I None 0 8.69E-05 None 9.95E-05 0 None 0 None 4.62E-05 0 0
P/R 2105 Ig-10 28 rs547169244 0.9882 -0.529 1.0 D 0.772 0.816 0.694656268378 gnomAD-3.1.2 1.32E-05 None None None None I None 0 1.30993E-04 0 0 0 None 0 0 0 0 0
P/R 2105 Ig-10 28 rs547169244 0.9882 -0.529 1.0 D 0.772 0.816 0.694656268378 1000 genomes 1.99681E-04 None None None None I None 0 1.4E-03 None None 0 0 None None None 0 None
P/R 2105 Ig-10 28 rs547169244 0.9882 -0.529 1.0 D 0.772 0.816 0.694656268378 gnomAD-4.0.0 1.02455E-05 None None None None I None 0 8.47371E-05 None 4.09031E-05 0 None 3.13804E-05 0 0 0 0
P/S 2201 Ig-11 28 rs763426070 0.481 -1.095 1.0 N 0.793 0.418 0.119812018005 gnomAD-2.1.1 7.97E-06 None None None None N None 0 0 None 0 0 None 6.53E-05 None 0 0 0
D/N 2472 Ig-14 28 rs1486709515 0.1755 0.552 1.0 N 0.679 0.454 0.419957187557 gnomAD-2.1.1 3.99E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
D/N 2472 Ig-14 28 rs1486709515 0.1755 0.552 1.0 N 0.679 0.454 0.419957187557 gnomAD-4.0.0 3.18146E-06 None None None None I None 0 0 None 4.7669E-05 0 None 0 0 0 1.43279E-05 0
S/Y 2559 Ig-15 27 None 0.2087 None 0.912 N 0.547 0.434 0.606724348718 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
N/D 2734 Ig-17 28 rs775219028 0.056 0.441 None N 0.083 0.198 0.0401082797425 gnomAD-2.1.1 7.96E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.76E-05 0
N/D 2734 Ig-17 28 rs775219028 0.056 0.441 None N 0.083 0.198 0.0401082797425 gnomAD-4.0.0 1.36815E-06 None None None None N None 0 0 None 0 0 None 0 0 1.7986E-06 0 0
N/H 2734 Ig-17 28 rs775219028 0.1168 -0.043 0.171 D 0.409 0.206 0.112648838833 gnomAD-2.1.1 3.98E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
N/H 2734 Ig-17 28 rs775219028 0.1168 -0.043 0.171 D 0.409 0.206 0.112648838833 gnomAD-4.0.0 6.84075E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15931E-05 0
N/K 2734 Ig-17 28 None 0.2016 None 0.012 N 0.349 0.128 0.0551355673512 gnomAD-4.0.0 1.59052E-06 None None None None N None 5.65163E-05 0 None 0 0 None 0 0 0 0 0
D/E 2821 Ig-18 27 None 0.6202 None 0.767 N 0.353 0.271 0.267755039894 gnomAD-4.0.0 1.59048E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85647E-06 0 0
D/Y 2821 Ig-18 27 None 0.8616 None 1.0 D 0.772 0.585 0.788725443766 gnomAD-4.0.0 1.59049E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85647E-06 0 0
N/S 2909 Ig-19 28 rs1300254374 0.2039 0.143 0.999 N 0.633 0.4 0.26547132957 gnomAD-2.1.1 1.77E-05 None None None None I None 0 8.47E-05 None 0 0 None 0 None 0 1.55E-05 0
N/S 2909 Ig-19 28 rs1300254374 0.2039 0.143 0.999 N 0.633 0.4 0.26547132957 gnomAD-3.1.2 5.92E-05 None None None None I None 0 4.58235E-04 0 0 0 None 0 0 2.94E-05 0 0
N/S 2909 Ig-19 28 rs1300254374 0.2039 0.143 0.999 N 0.633 0.4 0.26547132957 gnomAD-4.0.0 1.487E-05 None None None None I None 1.33472E-05 1.83339E-04 None 0 0 None 0 0 1.01695E-05 0 0
N/Y 2909 Ig-19 28 None 0.7049 None 1.0 D 0.588 0.626 0.697725006634 gnomAD-4.0.0 7.52473E-06 None None None None I None 0 0 None 0 0 None 0 0 9.89225E-06 0 0
E/D 2995 Ig-20 27 None 0.3224 None 0.999 N 0.531 0.367 0.266385636622 gnomAD-4.0.0 6.84098E-07 None None None None N None 0 0 None 0 0 None 0 0 8.993E-07 0 0
D/E 3173 Ig-22 27 rs151129843 0.5847 None 0.092 N 0.359 0.068 0.0297737177859 gnomAD-4.0.0 5.47288E-06 None None None None N None 2.98686E-05 0 None 0 0 None 0 0 8.99308E-07 0 9.93608E-05
P/L 3266 Ig-23 28 None 0.9204 None 1.0 D 0.767 0.756 0.904293489814 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 3266 Ig-23 28 rs2090043271 0.9658 None 1.0 D 0.757 0.739 0.669000193909 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
P/L 3492 Ig-25 28 rs1418266828 0.8839 0.07 None None None 0.586 None gnomAD-2.1.1 8.04E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 1.65453E-04
P/L 3492 Ig-25 28 rs1418266828 0.8839 0.07 None None None 0.586 None gnomAD-4.0.0 4.77328E-06 None None None None I None 0 2.28624E-05 None 0 0 None 0 0 5.71611E-06 0 0
P/T 3492 Ig-25 28 rs1297125768 0.8638 -0.475 None None None 0.573 None gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
P/T 3492 Ig-25 28 rs1297125768 0.8638 -0.475 None None None 0.573 None gnomAD-4.0.0 1.59111E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85811E-06 0 0
S/F 3687 Ig-26 28 None 0.1744 None None None None 0.115 None gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
S/T 3687 Ig-26 28 None 0.0837 None None None None 0.08 None gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 4727 Ig-30 28 rs1212488962 0.2791 -0.207 1.0 N 0.747 0.693 0.488477830397 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/S 4727 Ig-30 28 rs1212488962 0.2791 -0.207 1.0 N 0.747 0.693 0.488477830397 gnomAD-4.0.0 2.60045E-05 None None None None I None 0 0 None 0 0 None 0 0 3.05841E-05 0 6.6291E-05
P/L 4822 Ig-31 28 rs1381535545 0.8262 -0.032 0.959 D 0.554 0.555 0.845233866649 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
P/L 4822 Ig-31 28 rs1381535545 0.8262 -0.032 0.959 D 0.554 0.555 0.845233866649 gnomAD-4.0.0 4.10534E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39684E-06 0 0
P/S 4822 Ig-31 28 rs762428750 0.8772 -0.297 0.159 D 0.109 0.51 0.375326005269 gnomAD-2.1.1 2.81E-05 None None None None I None 0 5.8E-05 None 0 0 None 3.27E-05 None 0 3.55E-05 0
P/S 4822 Ig-31 28 rs762428750 0.8772 -0.297 0.159 D 0.109 0.51 0.375326005269 gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 2.07297E-04 0
P/S 4822 Ig-31 28 rs762428750 0.8772 -0.297 0.159 D 0.109 0.51 0.375326005269 gnomAD-4.0.0 1.11547E-05 None None None None I None 1.33465E-05 3.33444E-05 None 0 0 None 0 0 1.01713E-05 2.19602E-05 1.60133E-05
G/R 5102 Ig-34 28 None 0.4146 None 0.999 N 0.714 0.5 0.716320526391 gnomAD-4.0.0 1.59285E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86113E-06 0 0
E/G 5195 Ig-35 28 rs72648931 0.1188 -0.117 0.454 N 0.415 0.244 None gnomAD-2.1.1 9.81729E-04 None None None None I None 1.08696E-02 3.39443E-04 None 0 0 None 0 None 0 0 0
E/G 5195 Ig-35 28 rs72648931 0.1188 -0.117 0.454 N 0.415 0.244 None gnomAD-3.1.2 2.82582E-03 None None None None I None 9.91413E-03 1.04781E-03 0 0 0 None 0 0 0 0 1.43678E-03
E/G 5195 Ig-35 28 rs72648931 0.1188 -0.117 0.454 N 0.415 0.244 None 1000 genomes 2.39617E-03 None None None None I None 9.1E-03 0 None None 0 0 None None None 0 None
E/G 5195 Ig-35 28 rs72648931 0.1188 -0.117 0.454 N 0.415 0.244 None gnomAD-4.0.0 4.85801E-04 None None None None I None 9.52724E-03 4.99917E-04 None 0 0 None 0 0 1.18669E-05 0 4.00154E-04
P/L 5288 Ig-36 28 None 0.5818 None 1.0 D 0.639 0.728 0.895153570487 gnomAD-4.0.0 1.36842E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79895E-06 0 0
L/F 5384 Ig-37 28 rs879244251 0.182 None 0.966 N 0.386 0.323 0.663891511034 gnomAD-4.0.0 6.84362E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99548E-07 0 0
L/V 5384 Ig-37 28 None 0.1296 None 0.891 N 0.345 0.218 0.615873902259 gnomAD-4.0.0 6.84362E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99548E-07 0 0
T/I 5477 Ig-38 28 rs2080755955 0.0825 None 0.01 N 0.42 0.125 0.252162846088 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
T/I 5477 Ig-38 28 rs2080755955 0.0825 None 0.01 N 0.42 0.125 0.252162846088 gnomAD-4.0.0 1.23974E-06 None None None None I None 1.33551E-05 0 None 0 2.23244E-05 None 0 0 0 0 0
T/P 5477 Ig-38 28 rs756878354 0.0565 -0.121 None N 0.165 0.213 0.0551355673512 gnomAD-2.1.1 4.04E-06 None None None None I None 6.47E-05 0 None 0 0 None 0 None 0 0 0
T/P 5477 Ig-38 28 rs756878354 0.0565 -0.121 None N 0.165 0.213 0.0551355673512 gnomAD-3.1.2 6.59E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
T/P 5477 Ig-38 28 rs756878354 0.0565 -0.121 None N 0.165 0.213 0.0551355673512 gnomAD-4.0.0 6.58605E-06 None None None None I None 2.42002E-05 0 None 0 0 None 0 0 0 0 0
P/S 5571 Ig-39 29 rs566415754 0.2809 -0.191 1.0 D 0.665 0.586 0.607079148747 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 5571 Ig-39 29 rs566415754 0.2809 -0.191 1.0 D 0.665 0.586 0.607079148747 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07383E-04 0
P/S 5571 Ig-39 29 rs566415754 0.2809 -0.191 1.0 D 0.665 0.586 0.607079148747 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 0 None None None 1E-03 None
P/S 5571 Ig-39 29 rs566415754 0.2809 -0.191 1.0 D 0.665 0.586 0.607079148747 gnomAD-4.0.0 6.56918E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.07555E-04 0
P/L 5664 Ig-40 28 None 0.1139 None 0.379 D 0.431 0.504 0.73019596334 gnomAD-4.0.0 1.59139E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85856E-06 0 0
P/S 5664 Ig-40 28 None 0.1152 None 0.045 N 0.213 0.327 0.252681307341 gnomAD-4.0.0 6.84239E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99504E-07 0 0
P/T 5664 Ig-40 28 None 0.117 None 0.004 D 0.215 0.397 0.393316636838 gnomAD-4.0.0 2.05272E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69851E-06 0 0
K/E 5850 Ig-42 28 rs753692209 0.1351 0.04 0.994 N 0.579 0.321 0.460438652622 gnomAD-2.1.1 7.13E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.56E-05 0
K/E 5850 Ig-42 28 rs753692209 0.1351 0.04 0.994 N 0.579 0.321 0.460438652622 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
K/E 5850 Ig-42 28 rs753692209 0.1351 0.04 0.994 N 0.579 0.321 0.460438652622 gnomAD-4.0.0 2.29298E-05 None None None None I None 0 0 None 0 0 None 0 0 3.13634E-05 0 0
K/N 5850 Ig-42 28 rs1364212803 0.4279 0.121 0.999 N 0.655 0.408 0.290590437066 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
K/N 5850 Ig-42 28 rs1364212803 0.4279 0.121 0.999 N 0.655 0.408 0.290590437066 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
K/N 5850 Ig-42 28 rs1364212803 0.4279 0.121 0.999 N 0.655 0.408 0.290590437066 gnomAD-4.0.0 6.84237E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99514E-07 0 0
K/R 5850 Ig-42 28 None 0.0854 None 0.998 N 0.623 0.373 0.442054744378 gnomAD-4.0.0 1.59141E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85869E-06 0 0
H/L 5946 Ig-43 28 None 0.1299 None 0.005 N 0.139 0.287 0.503498835695 gnomAD-4.0.0 6.84283E-07 None None None None I None 2.98846E-05 0 None 0 0 None 0 0 0 0 0
H/R 5946 Ig-43 28 rs1417520677 0.1913 None 0.986 N 0.466 0.398 0.307332253619 gnomAD-4.0.0 1.36857E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79909E-06 0 0
H/Y 5946 Ig-43 28 rs1251182445 0.123 0.957 0.986 N 0.46 0.402 0.4744847356 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
H/Y 5946 Ig-43 28 rs1251182445 0.123 0.957 0.986 N 0.46 0.402 0.4744847356 gnomAD-4.0.0 2.73716E-06 None None None None I None 0 0 None 0 0 None 0 0 1.7991E-06 2.31889E-05 0
P/H 6226 Ig-46 28 rs746345160 0.1548 None 0.295 D 0.547 0.539 None gnomAD-3.1.2 1.97E-05 None None None None I None 7.25E-05 0 0 0 0 None 0 0 0 0 0
P/H 6226 Ig-46 28 rs746345160 0.1548 None 0.295 D 0.547 0.539 None gnomAD-4.0.0 1.9728E-05 None None None None I None 7.24673E-05 0 None 0 0 None 0 0 0 0 0
P/L 6226 Ig-46 28 rs746345160 0.1008 -0.045 0.012 D 0.427 0.388 None gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
P/L 6226 Ig-46 28 rs746345160 0.1008 -0.045 0.012 D 0.427 0.388 None gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 6226 Ig-46 28 rs746345160 0.1008 -0.045 0.012 D 0.427 0.388 None gnomAD-4.0.0 8.05745E-06 None None None None I None 0 0 None 0 0 None 0 3.29272E-04 8.47722E-06 0 1.60138E-05
P/S 6226 Ig-46 28 rs1466849790 0.0746 -0.599 None N 0.139 0.32 None gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/S 6226 Ig-46 28 rs1466849790 0.0746 -0.599 None N 0.139 0.32 None gnomAD-4.0.0 2.05288E-06 None None None None I None 8.96807E-05 0 None 0 0 None 0 0 0 0 0
P/T 6226 Ig-46 28 rs1466849790 0.0895 None None D 0.188 0.33 0.0401082797425 gnomAD-4.0.0 6.84292E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9957E-07 0 0
P/L 6319 Ig-47 28 rs2079901596 0.0784 None 0.032 D 0.321 0.517 0.638853250657 gnomAD-4.0.0 1.59475E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02994E-05
P/S 6319 Ig-47 28 rs749058126 0.0919 -0.086 0.942 D 0.4 0.558 0.487772906946 gnomAD-2.1.1 8.17E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.81E-05 0
P/S 6319 Ig-47 28 rs749058126 0.0919 -0.086 0.942 D 0.4 0.558 0.487772906946 gnomAD-4.0.0 2.05466E-05 None None None None I None 0 0 None 0 0 None 0 0 2.60982E-05 0 1.65837E-05
P/Q 6412 Ig-48 28 None 0.9342 None 1.0 D 0.636 0.753 0.631970868704 gnomAD-4.0.0 3.60097E-06 None None None None I None 0 0 None 0 0 None 0 0 3.93751E-06 0 0
L/V 6508 Ig-49 28 None 0.1274 None 0.948 N 0.487 0.217 0.536334086147 gnomAD-4.0.0 1.59281E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02847E-05
P/L 6601 Ig-50 28 None 0.1075 None 0.942 D 0.619 0.725 0.551384154659 gnomAD-4.0.0 6.84477E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65733E-05
P/Q 6601 Ig-50 28 rs1578111426 0.1391 None 0.126 D 0.311 0.638 0.398133443147 gnomAD-4.0.0 6.84477E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99771E-07 0 0
P/S 6601 Ig-50 28 rs1175980116 0.1169 -0.379 0.698 D 0.502 0.602 0.490144168196 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/S 6601 Ig-50 28 rs1175980116 0.1169 -0.379 0.698 D 0.502 0.602 0.490144168196 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/S 6601 Ig-50 28 rs1175980116 0.1169 -0.379 0.698 D 0.502 0.602 0.490144168196 gnomAD-4.0.0 6.81922E-06 None None None None I None 2.67123E-05 0 None 0 0 None 0 0 5.93521E-06 0 3.20349E-05
P/L 6695 Ig-51 29 None 0.7007 None 0.936 D 0.523 0.504 0.728988515233 gnomAD-4.0.0 1.59292E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86118E-06 0 0
P/S 6695 Ig-51 29 rs1278595517 0.6598 -0.206 0.137 D 0.224 0.437 0.369867359543 gnomAD-2.1.1 4.03E-06 None None None None I None 0 2.91E-05 None 0 0 None 0 None 0 0 0
P/S 6695 Ig-51 29 rs1278595517 0.6598 -0.206 0.137 D 0.224 0.437 0.369867359543 gnomAD-4.0.0 1.59304E-06 None None None None I None 0 2.29022E-05 None 0 0 None 0 0 0 0 0
P/L 6788 Ig-52 28 None 0.4439 None 0.919 D 0.62 0.59 0.863795767011 gnomAD-4.0.0 6.84992E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00182E-07 0 0
P/T 6788 Ig-52 28 rs2154304599 0.4577 None 0.414 D 0.463 0.553 0.604527667468 gnomAD-4.0.0 3.42457E-06 None None None None I None 0 0 None 0 0 None 0 0 4.50061E-06 0 0
Q/L 6881 Ig-53 28 None 0.1074 None 0.324 N 0.477 0.193 0.367992661779 gnomAD-4.0.0 2.73805E-06 None None None None I None 0 0 None 0 0 None 0 0 3.5989E-06 0 0
P/L 6975 Ig-54 28 rs374493881 0.522 0.018 0.998 D 0.57 0.615 None gnomAD-2.1.1 2.82E-05 None None None None I None 1.93874E-04 0 None 0 5.58E-05 None 0 None 0 2.67E-05 0
P/L 6975 Ig-54 28 rs374493881 0.522 0.018 0.998 D 0.57 0.615 None gnomAD-3.1.2 6.58E-05 None None None None I None 1.93115E-04 0 0 0 1.92976E-04 None 0 0 0 0 4.78011E-04
P/L 6975 Ig-54 28 rs374493881 0.522 0.018 0.998 D 0.57 0.615 None gnomAD-4.0.0 2.54156E-05 None None None None I None 2.40442E-04 0 None 0 2.22985E-05 None 0 1.64636E-04 1.27172E-05 3.29468E-05 4.80646E-05
P/A 7164 Ig-56 28 rs927054837 0.0734 None 0.248 D 0.273 0.443 0.270889551736 gnomAD-4.0.0 1.36911E-05 None None None None I None 0 0 None 0 0 None 0 0 1.79939E-05 0 0
P/L 7164 Ig-56 28 rs981191810 0.0987 -0.075 0.961 D 0.593 0.51 None gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.79E-05 0
P/L 7164 Ig-56 28 rs981191810 0.0987 -0.075 0.961 D 0.593 0.51 None gnomAD-3.1.2 1.31E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/L 7164 Ig-56 28 rs981191810 0.0987 -0.075 0.961 D 0.593 0.51 None gnomAD-4.0.0 3.84664E-06 None None None None I None 3.38444E-05 0 None 0 0 None 0 0 2.3946E-06 0 0
P/A 7350 Ig-58 28 rs2078649611 0.6657 None 0.958 D 0.544 0.674 0.505701759113 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 0 2.07383E-04 0
P/A 7350 Ig-58 28 rs2078649611 0.6657 None 0.958 D 0.544 0.674 0.505701759113 gnomAD-4.0.0 2.5642E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.68183E-05 0
P/Q 7350 Ig-58 28 rs1467666220 0.8574 None 0.999 D 0.638 0.72 0.714142150149 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/Q 7350 Ig-58 28 rs1467666220 0.8574 None 0.999 D 0.638 0.72 0.714142150149 gnomAD-4.0.0 2.56447E-06 None None None None I None 0 0 None 0 0 None 0 0 4.7895E-06 0 0
A/T 7446 Ig-59 28 None 0.0733 None 0.012 N 0.385 0.151 0.218112801441 gnomAD-4.0.0 1.59196E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.0259E-05
Q/P 7542 Ig-60 28 None 0.092 None 0.003 N 0.153 0.255 0.112648838833 gnomAD-4.0.0 1.59226E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.4346E-05 0
P/A 7636 Ig-61 29 rs1220583171 0.3158 -0.024 0.883 D 0.561 0.548 0.449187354989 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
P/A 7636 Ig-61 29 rs1220583171 0.3158 -0.024 0.883 D 0.561 0.548 0.449187354989 gnomAD-4.0.0 3.18538E-06 None None None None I None 0 0 None 0 0 None 0 0 5.72318E-06 0 0
P/L 7729 Ig-62 28 None 0.374 None 0.928 D 0.452 0.583 0.781312296865 gnomAD-4.0.0 6.84418E-07 None None None None I None 0 0 None 0 0 None 0 0 0 0 1.65755E-05
Q/H 7822 Ig-63 28 None 0.2353 None 0.921 N 0.423 0.384 0.358134431457 gnomAD-4.0.0 1.5915E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85873E-06 0 0
P/R 7916 Ig-64 28 rs764130233 0.7429 0.367 0.467 D 0.411 0.544 0.503930629158 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 0 None 0 None 9.29E-05 1.78E-05 0
P/R 7916 Ig-64 28 rs764130233 0.7429 0.367 0.467 D 0.411 0.544 0.503930629158 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 9.43E-05 0 0 0 0
P/R 7916 Ig-64 28 rs764130233 0.7429 0.367 0.467 D 0.411 0.544 0.503930629158 gnomAD-4.0.0 2.29309E-05 None None None None I None 0 0 None 0 0 None 2.3439E-04 0 1.69534E-05 0 3.20266E-05
P/S 7916 Ig-64 28 rs1264639309 0.7696 None 0.999 D 0.614 0.609 0.568535626052 gnomAD-4.0.0 1.59153E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02517E-05
A/P 8012 Ig-65 28 rs749655622 0.0836 -0.364 None N 0.113 0.289 0.201204373187 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.88E-06 0
A/P 8012 Ig-65 28 rs749655622 0.0836 -0.364 None N 0.113 0.289 0.201204373187 gnomAD-4.0.0 1.59122E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85834E-06 0 0
A/T 8012 Ig-65 28 rs749655622 0.0816 None 0.042 N 0.371 0.127 0.299086750705 gnomAD-4.0.0 1.59122E-06 None None None None I None 0 0 None 0 0 None 0 0 0 0 3.02407E-05
P/R 8105 Ig-66 28 rs1215904654 0.1594 -0.024 0.984 D 0.597 0.614 0.656596202622 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/R 8105 Ig-66 28 rs1215904654 0.1594 -0.024 0.984 D 0.597 0.614 0.656596202622 gnomAD-4.0.0 3.18352E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.86648E-05 0
P/S 8105 Ig-66 28 None 0.1237 None 0.251 D 0.314 0.432 0.362758974969 gnomAD-4.0.0 6.84299E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9952E-07 0 0
P/T 8291 Ig-68 28 None 0.8405 None 0.992 D 0.714 0.576 0.761910172549 gnomAD-4.0.0 1.60168E-06 None None None None I None 0 0 None 0 0 None 2.03252E-05 0 0 0 0
E/G 8387 Ig-69 28 None 0.1946 None 0.855 N 0.327 0.149 0.185906805712 gnomAD-4.0.0 1.59212E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85963E-06 0 0
A/T 8483 Ig-70 28 rs1156463241 0.08 -0.564 0.001 N 0.25 0.268 0.158396225186 gnomAD-2.1.1 3.18E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.48E-05 0
A/T 8483 Ig-70 28 rs1156463241 0.08 -0.564 0.001 N 0.25 0.268 0.158396225186 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
A/T 8483 Ig-70 28 rs1156463241 0.08 -0.564 0.001 N 0.25 0.268 0.158396225186 gnomAD-4.0.0 3.09871E-06 None None None None I None 0 0 None 0 0 None 0 0 4.23837E-06 0 0
P/T 8577 Ig-71 29 None 0.3484 None 0.03 D 0.261 0.602 0.418095516054 gnomAD-4.0.0 1.59731E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86814E-06 0 0
P/A 8670 Ig-72 28 rs1577904664 0.0941 None 0.012 N 0.146 0.331 0.252681307341 gnomAD-4.0.0 5.47397E-06 None None None None I None 0 0 None 0 0 None 0 0 7.19622E-06 0 0
P/H 8670 Ig-72 28 rs770195041 0.3952 -0.239 0.999 D 0.53 0.631 0.677392558384 gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/H 8670 Ig-72 28 rs770195041 0.3952 -0.239 0.999 D 0.53 0.631 0.677392558384 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/H 8670 Ig-72 28 rs770195041 0.3952 -0.239 0.999 D 0.53 0.631 0.677392558384 gnomAD-4.0.0 1.23948E-06 None None None None I None 2.67144E-05 0 None 0 0 None 0 0 0 0 0
P/L 8670 Ig-72 28 rs770195041 0.2095 None 0.841 D 0.401 0.577 0.746547232912 gnomAD-4.0.0 1.36849E-05 None None None None I None 0 0 None 0 0 None 0 0 1.7091E-05 0 1.65651E-05
P/S 8670 Ig-72 28 None 0.1836 None 0.781 D 0.395 0.42 0.344251166708 gnomAD-4.0.0 6.84246E-07 None None None None I None 0 0 None 3.8276E-05 0 None 0 0 0 0 0
P/T 8670 Ig-72 28 None 0.2213 None 0.761 D 0.439 0.46 0.529510553188 gnomAD-4.0.0 1.36849E-06 None None None None I None 5.97872E-05 0 None 0 0 None 0 0 0 0 0
E/A 8763 Ig-73 28 rs1453342840 0.0931 0.161 0.567 N 0.478 0.254 0.365120060079 gnomAD-2.1.1 6.37E-05 None None None None I None 2.29621E-04 0 None 0 0 None 0 None 0 0 0
E/A 8763 Ig-73 28 rs1453342840 0.0931 0.161 0.567 N 0.478 0.254 0.365120060079 gnomAD-3.1.2 1.97E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 0 0 0
E/A 8763 Ig-73 28 rs1453342840 0.0931 0.161 0.567 N 0.478 0.254 0.365120060079 gnomAD-4.0.0 1.97174E-05 None None None None I None 7.23903E-05 0 None 0 0 None 0 0 0 0 0
P/S 8857 Ig-74 28 rs1317672432 0.5895 0.082 1.0 D 0.659 0.777 0.558889990735 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 4.65E-05 0 0
P/S 8857 Ig-74 28 rs1317672432 0.5895 0.082 1.0 D 0.659 0.777 0.558889990735 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 9.42E-05 0 0 0 0
P/S 8857 Ig-74 28 rs1317672432 0.5895 0.082 1.0 D 0.659 0.777 0.558889990735 gnomAD-4.0.0 3.84438E-06 None None None None I None 0 0 None 0 0 None 4.70898E-05 0 0 0 0
P/L 8953 Ig-75 28 rs1195723456 0.1147 None 0.98 D 0.531 0.625 0.862594239932 gnomAD-4.0.0 1.60145E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.45033E-05 0
P/S 8953 Ig-75 28 rs756003188 0.1207 -0.289 0.659 D 0.235 0.515 0.429203605099 gnomAD-2.1.1 3.75E-05 None None None None I None 0 1.19624E-04 None 1.01626E-04 0 None 0 None 4.72E-05 2.78E-05 0
P/S 8953 Ig-75 28 rs756003188 0.1207 -0.289 0.659 D 0.235 0.515 0.429203605099 gnomAD-3.1.2 9.2E-05 None None None None I None 0 5.89468E-04 0 0 0 None 2.82912E-04 0 2.94E-05 0 0
P/S 8953 Ig-75 28 rs756003188 0.1207 -0.289 0.659 D 0.235 0.515 0.429203605099 gnomAD-4.0.0 2.29953E-05 None None None None I None 0 2.36048E-04 None 0 0 None 1.25372E-04 0 1.27403E-05 0 0
P/S 9046 Ig-76 28 rs772800519 0.1263 -0.592 0.136 N 0.16 0.4 0.317084106153 gnomAD-2.1.1 2.82E-05 None None None None I None 0 2.03678E-04 None 0 0 None 0 None 0 0 0
P/S 9046 Ig-76 28 rs772800519 0.1263 -0.592 0.136 N 0.16 0.4 0.317084106153 gnomAD-4.0.0 6.84321E-06 None None None None I None 0 2.01468E-04 None 3.82878E-05 0 None 0 0 0 0 0
P/L 9139 Ig-77 28 rs770133378 0.111 0.035 0.018 D 0.327 0.478 0.585352569408 gnomAD-2.1.1 8.03E-06 None None None None I None 0 0 None 0 0 None 6.54E-05 None 0 0 0
P/L 9139 Ig-77 28 rs770133378 0.111 0.035 0.018 D 0.327 0.478 0.585352569408 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 0 4.14422E-04 0
P/L 9139 Ig-77 28 rs770133378 0.111 0.035 0.018 D 0.327 0.478 0.585352569408 gnomAD-4.0.0 1.36338E-05 None None None None I None 0 0 None 0 0 None 0 0 0 2.41546E-04 0
P/L 9232 Ig-78 28 rs1354298331 0.8282 0.039 0.942 D 0.529 0.702 0.839298628363 gnomAD-2.1.1 8.05E-06 None None None None I None 6.52E-05 2.9E-05 None 0 0 None 0 None 0 0 0
P/L 9232 Ig-78 28 rs1354298331 0.8282 0.039 0.942 D 0.529 0.702 0.839298628363 gnomAD-4.0.0 1.59123E-06 None None None None I None 0 2.28686E-05 None 0 0 None 0 0 0 0 0
P/S 9232 Ig-78 28 rs1228009511 0.8647 0.077 0.942 D 0.407 0.725 0.585777056924 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/S 9232 Ig-78 28 rs1228009511 0.8647 0.077 0.942 D 0.407 0.725 0.585777056924 gnomAD-4.0.0 1.59122E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85817E-06 0 0
E/D 9328 Ig-79 28 rs1577830171 0.1246 None 0.472 None 0.393 0.092 0.238096912614 gnomAD-4.0.0 1.5911E-06 None None None None I None 0 2.28634E-05 None 0 0 None 0 0 0 0 0
Q/K 9424 Ig-80 28 rs748778927 0.1066 0.3 0.27 None 0.317 0.279 0.193865811164 gnomAD-2.1.1 7.13E-06 None None None None I None 4.13E-05 0 None 0 0 None 0 None 0 7.8E-06 0
Q/K 9424 Ig-80 28 rs748778927 0.1066 0.3 0.27 None 0.317 0.279 0.193865811164 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
Q/K 9424 Ig-80 28 rs748778927 0.1066 0.3 0.27 None 0.317 0.279 0.193865811164 gnomAD-4.0.0 4.33777E-06 None None None None I None 5.34045E-05 0 None 0 0 None 0 0 2.54274E-06 0 0
Q/E 9521 Ig-81 29 None 0.1318 None 0.977 None 0.503 0.306 0.300110245524 gnomAD-4.0.0 6.842E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99436E-07 0 0
Q/L 9521 Ig-81 29 None 0.1934 None 0.98 None 0.472 0.528 0.649088479846 gnomAD-4.0.0 1.59113E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85791E-06 0 0
Q/P 9521 Ig-81 29 rs760280055 0.1345 0.227 0.997 None 0.434 0.486 0.338110398507 gnomAD-2.1.1 7.13E-06 None None None None I None 8.27E-05 0 None 0 0 None 0 None 0 0 0
Q/P 9521 Ig-81 29 rs760280055 0.1345 0.227 0.997 None 0.434 0.486 0.338110398507 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
Q/P 9521 Ig-81 29 rs760280055 0.1345 0.227 0.997 None 0.434 0.486 0.338110398507 gnomAD-4.0.0 6.57117E-06 None None None None I None 2.41208E-05 0 None 0 0 None 0 0 0 0 0
E/K 9617 Ig-82 28 rs144025230 0.1753 0.805 0.454 None 0.393 0.209 None gnomAD-2.1.1 4.28E-05 None None None None I None 0 0 None 0 0 None 0 None 0 9.35E-05 0
E/K 9617 Ig-82 28 rs144025230 0.1753 0.805 0.454 None 0.393 0.209 None gnomAD-3.1.2 5.91E-05 None None None None I None 0 0 0 0 1.9253E-04 None 0 0 1.17564E-04 0 0
E/K 9617 Ig-82 28 rs144025230 0.1753 0.805 0.454 None 0.393 0.209 None 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 1E-03 None None None 0 None
E/K 9617 Ig-82 28 rs144025230 0.1753 0.805 0.454 None 0.393 0.209 None gnomAD-4.0.0 3.22185E-05 None None None None I None 0 0 None 0 4.45633E-05 None 0 0 4.06828E-05 0 3.20061E-05
P/S 9928 Ig-84 29 None 0.8533 None 1.0 None 0.753 0.618 0.549504238362 gnomAD-4.0.0 6.8528E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00165E-07 0 0
P/L 10015 Ig-85 27 rs1178694077 0.7114 0.211 1.0 None 0.677 0.675 0.78927792584 gnomAD-2.1.1 3.18E-05 None None None None I None 1.14705E-04 0 None 0 0 None 0 None 0 0 0
P/L 10015 Ig-85 27 rs1178694077 0.7114 0.211 1.0 None 0.677 0.675 0.78927792584 gnomAD-3.1.2 1.31E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/L 10015 Ig-85 27 rs1178694077 0.7114 0.211 1.0 None 0.677 0.675 0.78927792584 gnomAD-4.0.0 4.05983E-06 None None None None I None 5.24384E-05 0 None 0 0 None 0 0 1.2049E-06 0 0
P/S 10015 Ig-85 27 rs779333871 0.7005 -0.213 1.0 None 0.686 0.658 0.550503487074 gnomAD-2.1.1 4.01E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 10015 Ig-85 27 rs779333871 0.7005 -0.213 1.0 None 0.686 0.658 0.550503487074 gnomAD-4.0.0 7.95434E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85752E-06 5.73082E-05 0
D/H 13900 Ig-89 25 rs1188616797 0.8379 -0.277 0.862 N 0.367 0.403 0.260249123532 gnomAD-2.1.1 9.13E-06 None None None None N None 7.44E-05 0 None 0 0 None 3.66E-05 None 0 0 0
D/H 13900 Ig-89 25 rs1188616797 0.8379 -0.277 0.862 N 0.367 0.403 0.260249123532 gnomAD-4.0.0 3.28008E-06 None None None None N None 5.72541E-05 0 None 0 0 None 0 0 0 1.49107E-05 0
D/G 13992 Ig-90 28 None 0.6555 None 1.0 N 0.767 0.479 0.15556083564 gnomAD-4.0.0 5.47514E-06 None None None None N None 0 0 None 0 0 None 0 0 7.19723E-06 0 0
D/H 13992 Ig-90 28 rs778681628 0.8844 0.655 1.0 N 0.79 0.398 0.17258766438 gnomAD-2.1.1 8.05E-06 None None None None N None 0 5.8E-05 None 0 0 None 0 None 0 0 0
D/H 13992 Ig-90 28 rs778681628 0.8844 0.655 1.0 N 0.79 0.398 0.17258766438 gnomAD-4.0.0 3.18458E-06 None None None None N None 0 4.57498E-05 None 0 0 None 0 0 0 0 0
D/V 13992 Ig-90 28 None 0.87 None 1.0 N 0.755 0.557 0.429435026966 gnomAD-4.0.0 6.84392E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99654E-07 0 0
P/L 14345 Ig-94 27 None 0.2451 None 0.974 D 0.46 0.354 0.435371449458 gnomAD-4.0.0 1.36889E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99682E-07 0 1.65739E-05
P/R 14345 Ig-94 27 rs1228136995 0.3131 -0.829 0.949 N 0.445 0.373 0.31501682445 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14758E-04 0 None 0 0 None 0 None 0 0 0
P/R 14345 Ig-94 27 rs1228136995 0.3131 -0.829 0.949 N 0.445 0.373 0.31501682445 gnomAD-3.1.2 6.58E-06 None None None None N None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/R 14345 Ig-94 27 rs1228136995 0.3131 -0.829 0.949 N 0.445 0.373 0.31501682445 gnomAD-4.0.0 1.23984E-06 None None None None N None 2.67165E-05 0 None 0 0 None 0 0 0 0 0
P/S 14345 Ig-94 27 rs1576701632 0.1914 None 0.842 N 0.381 0.262 0.223847106136 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
P/S 14345 Ig-94 27 rs1576701632 0.1914 None 0.842 N 0.381 0.262 0.223847106136 gnomAD-4.0.0 6.57583E-06 None None None None N None 0 6.55652E-05 None 0 0 None 0 0 0 0 0
P/A 14435 Ig-95 28 None 0.34 None 0.37 D 0.247 0.346 0.386558576397 gnomAD-4.0.0 6.84374E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99628E-07 0 0
P/L 14435 Ig-95 28 rs2059952331 0.6232 None 0.241 D 0.315 0.484 0.491592572028 gnomAD-4.0.0 6.36857E-06 None None None None N None 0 0 None 0 0 None 0 0 1.14397E-05 0 0
D/E 14523 Ig-96 27 rs758154539 0.2687 -0.047 0.02 N 0.301 0.277 0.124217242631 gnomAD-2.1.1 8.44E-06 None None None None N None 0 0 None 0 0 None 3.44E-05 None 0 9.37E-06 0
D/E 14523 Ig-96 27 rs758154539 0.2687 -0.047 0.02 N 0.301 0.277 0.124217242631 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 2.07039E-04 0
D/E 14523 Ig-96 27 rs758154539 0.2687 -0.047 0.02 N 0.301 0.277 0.124217242631 gnomAD-4.0.0 4.97754E-06 None None None None N None 0 0 None 0 0 None 0 0 2.54966E-06 5.5605E-05 0
D/A 14701 Ig-98 27 rs1286396788 0.1193 None 0.012 N 0.267 0.135 0.178374595973 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
D/A 14701 Ig-98 27 rs1286396788 0.1193 None 0.012 N 0.267 0.135 0.178374595973 gnomAD-4.0.0 6.57341E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47046E-05 0 0
D/G 14701 Ig-98 27 None 0.127 None 0.058 N 0.276 0.146 0.154104182512 gnomAD-4.0.0 1.5922E-06 None None None None N None 0 0 None 0 0 None 0 0 2.8603E-06 0 0
E/D 15417 Ig-106 27 rs993637686 0.161 None 0.999 D 0.539 0.478 0.378148810121 gnomAD-4.0.0 1.79013E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.77847E-05 0
P/R 15595 Ig-108 28 None 0.9148 None 1.0 D 0.817 0.635 0.622259118589 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/S 15595 Ig-108 28 None 0.923 None 1.0 D 0.781 0.621 0.543647257999 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 15990 Ig-109 23 rs1253292798 0.9276 -0.084 1.0 D 0.761 0.65 0.787459768874 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.96E-06 0
P/L 15990 Ig-109 23 rs1253292798 0.9276 -0.084 1.0 D 0.761 0.65 0.787459768874 gnomAD-4.0.0 1.59339E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86248E-06 0 0
P/T 15990 Ig-109 23 rs2057439809 0.9458 None 1.0 D 0.744 0.697 0.618957995044 gnomAD-3.1.2 6.59E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 15990 Ig-109 23 rs2057439809 0.9458 None 1.0 D 0.744 0.697 0.618957995044 gnomAD-4.0.0 6.58597E-06 None None None None I None 0 0 None 0 0 None 0 0 1.47284E-05 0 0
P/T 16286 Ig-110 25 rs1033904978 0.9746 None 1.0 D 0.75 0.764 0.773923737282 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
P/R 16982 Ig-111 28 rs1402845968 0.9754 None 1.0 D 0.789 0.752 0.681754529401 gnomAD-2.1.1 3.19E-05 None None None None I None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
P/R 16982 Ig-111 28 rs1402845968 0.9754 None 1.0 D 0.789 0.752 0.681754529401 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/R 16982 Ig-111 28 rs1402845968 0.9754 None 1.0 D 0.789 0.752 0.681754529401 gnomAD-4.0.0 6.58276E-06 None None None None I None 2.41569E-05 0 None 0 0 None 0 0 0 0 0
P/S 16982 Ig-111 28 rs1178993608 0.9722 -0.622 1.0 D 0.751 0.783 0.606518698375 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.49E-05 0
P/S 16982 Ig-111 28 rs1178993608 0.9722 -0.622 1.0 D 0.751 0.783 0.606518698375 gnomAD-3.1.2 6.59E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 16982 Ig-111 28 rs1178993608 0.9722 -0.622 1.0 D 0.751 0.783 0.606518698375 gnomAD-4.0.0 3.84918E-06 None None None None I None 0 0 None 0 0 None 0 0 4.79207E-06 0 2.85014E-05
P/H 17275 Ig-112 25 None 0.9814 None 0.999 D 0.661 0.766 0.611492100817 gnomAD-4.0.0 1.36941E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79982E-06 0 0
P/S 17275 Ig-112 25 rs752852690 0.9818 -0.148 0.989 D 0.657 0.691 0.590995569847 gnomAD-2.1.1 1.43E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.14E-05 0
P/S 17275 Ig-112 25 rs752852690 0.9818 -0.148 0.989 D 0.657 0.691 0.590995569847 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/S 17275 Ig-112 25 rs752852690 0.9818 -0.148 0.989 D 0.657 0.691 0.590995569847 gnomAD-4.0.0 1.1784E-05 None None None None I None 0 0 None 0 0 None 0 0 1.61135E-05 0 0
P/T 17275 Ig-112 25 None 0.9587 None 0.978 D 0.656 0.705 0.627559020554 gnomAD-4.0.0 6.84704E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99913E-07 0 0
P/L 17700 Ig-113 24 rs767647740 0.9518 0.055 1.0 D 0.739 0.624 0.719680077433 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/L 17700 Ig-113 24 rs767647740 0.9518 0.055 1.0 D 0.739 0.624 0.719680077433 gnomAD-4.0.0 1.59242E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
P/S 18406 Ig-115 25 None 0.9671 None 1.0 D 0.759 0.623 0.677512986068 gnomAD-4.0.0 1.59328E-06 None None None None I None 0 0 None 0 0 None 0 0 2.8621E-06 0 0
P/A 18712 Ig-116 25 None 0.9156 None 1.0 D 0.753 0.828 0.599832994901 gnomAD-4.0.0 6.85089E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00135E-07 0 0
P/L 18712 Ig-116 25 rs780740937 0.9301 0.04 1.0 D 0.773 0.808 0.882796826995 gnomAD-2.1.1 4.05E-06 None None None None I None 0 2.93E-05 None 0 0 None 0 None 0 0 0
P/L 18712 Ig-116 25 rs780740937 0.9301 0.04 1.0 D 0.773 0.808 0.882796826995 gnomAD-4.0.0 1.59566E-06 None None None None I None 0 2.29474E-05 None 0 0 None 0 0 0 0 0
P/S 18712 Ig-116 25 rs747472312 0.9652 -0.798 1.0 D 0.764 0.829 0.59271447433 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 1.69147E-04 None 0 None 0 0 0
P/S 18712 Ig-116 25 rs747472312 0.9652 -0.798 1.0 D 0.764 0.829 0.59271447433 gnomAD-4.0.0 2.74036E-06 None None None None I None 0 0 None 0 7.59417E-05 None 0 0 9.00135E-07 0 0
P/L 19120 Ig-117 26 rs936369232 0.7952 0.019 1.0 D 0.761 0.586 0.803403390734 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.93E-06 0
P/L 19120 Ig-117 26 rs936369232 0.7952 0.019 1.0 D 0.761 0.586 0.803403390734 gnomAD-4.0.0 1.3688E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79924E-06 0 0
P/R 19120 Ig-117 26 None 0.9176 None 1.0 D 0.782 0.618 0.691061782995 gnomAD-4.0.0 4.10639E-06 None None None None I None 0 0 None 0 0 None 0 0 5.39773E-06 0 0
P/Q 19414 Ig-118 24 rs878901352 0.9847 -0.45 1.0 D 0.795 0.57 None gnomAD-2.1.1 1.79E-05 None None None None I None 2.06663E-04 0 None 0 0 None 0 None 0 0 0
P/Q 19414 Ig-118 24 rs878901352 0.9847 -0.45 1.0 D 0.795 0.57 None gnomAD-3.1.2 3.95E-05 None None None None I None 1.20645E-04 6.56E-05 0 0 0 None 0 0 0 0 0
P/Q 19414 Ig-118 24 rs878901352 0.9847 -0.45 1.0 D 0.795 0.57 None gnomAD-4.0.0 8.67809E-06 None None None None I None 1.60205E-04 1.66856E-05 None 0 0 None 0 0 0 0 1.60149E-05
P/S 19414 Ig-118 24 None 0.9894 None 1.0 D 0.773 0.575 0.713342169113 gnomAD-4.0.0 6.84377E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99575E-07 0 0
P/T 19414 Ig-118 24 None 0.9653 None 1.0 D 0.768 0.57 0.850758466603 gnomAD-4.0.0 1.36875E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79915E-06 0 0
P/S 19814 Ig-119 25 None 0.9894 None 1.0 D 0.698 0.697 0.648632380062 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/T 20106 Ig-120 27 rs1576103220 0.9242 None 1.0 D 0.743 0.563 0.597732455086 gnomAD-4.0.0 6.85284E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00281E-07 0 0
P/A 20504 Ig-121 26 rs765388232 0.9284 -0.077 1.0 D 0.762 0.711 0.717373546064 gnomAD-2.1.1 4.18E-06 None None None None I None 0 2.98E-05 None 0 0 None 0 None 0 0 0
P/A 20504 Ig-121 26 rs765388232 0.9284 -0.077 1.0 D 0.762 0.711 0.717373546064 gnomAD-4.0.0 6.88953E-07 None None None None I None 0 2.27759E-05 None 0 0 None 0 0 0 0 0
P/S 20504 Ig-121 26 rs765388232 0.9779 -0.286 1.0 D 0.77 0.718 0.734656905842 gnomAD-2.1.1 4.18E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.18E-06 0
P/S 20504 Ig-121 26 rs765388232 0.9779 -0.286 1.0 D 0.77 0.718 0.734656905842 gnomAD-4.0.0 6.88953E-07 None None None None I None 0 0 None 0 0 None 0 0 9.03417E-07 0 0
P/T 20504 Ig-121 26 None 0.9365 None 1.0 D 0.769 0.708 0.765495324787 gnomAD-4.0.0 2.75581E-06 None None None None I None 3.01332E-05 0 None 0 0 None 0 0 0 3.56752E-05 0
P/L 20797 Ig-122 29 None 0.976 None 1.0 D 0.755 0.604 0.828969124369 gnomAD-4.0.0 6.84547E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99818E-07 0 0
P/Q 20797 Ig-122 29 None 0.9931 None 1.0 D 0.775 0.707 0.682284130214 gnomAD-4.0.0 1.36909E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79964E-06 0 0
P/S 21202 Ig-123 26 rs752725604 0.9655 -0.077 1.0 D 0.661 0.783 0.600640161457 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 21202 Ig-123 26 rs752725604 0.9655 -0.077 1.0 D 0.661 0.783 0.600640161457 gnomAD-4.0.0 2.73823E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69925E-06 1.15988E-05 0
P/T 21202 Ig-123 26 None 0.9108 None 1.0 D 0.657 0.757 0.641703553165 gnomAD-4.0.0 6.84558E-07 None None None None I None 0 0 None 0 0 None 0 0 8.9975E-07 0 0
P/L 21494 Ig-124 26 rs587780492 0.9665 0.024 1.0 D 0.76 0.543 0.797964816289 gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.92E-05 0
P/L 21494 Ig-124 26 rs587780492 0.9665 0.024 1.0 D 0.76 0.543 0.797964816289 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/L 21494 Ig-124 26 rs587780492 0.9665 0.024 1.0 D 0.76 0.543 0.797964816289 gnomAD-4.0.0 2.54172E-05 None None None None I None 0 0 None 0 0 None 0 0 2.96759E-05 0 9.60922E-05
P/L 21891 Ig-125 26 rs397517662 0.965 0.086 1.0 D 0.759 0.653 None gnomAD-2.1.1 5.4E-05 None None None None I None 4.15E-05 1.706E-04 None 0 0 None 0 None 0 5.52E-05 1.41804E-04
P/L 21891 Ig-125 26 rs397517662 0.965 0.086 1.0 D 0.759 0.653 None gnomAD-3.1.2 8.56E-05 None None None None I None 2.42E-05 3.93391E-04 0 0 0 None 0 0 5.89E-05 0 9.58773E-04
P/L 21891 Ig-125 26 rs397517662 0.965 0.086 1.0 D 0.759 0.653 None gnomAD-4.0.0 5.08679E-05 None None None None I None 1.33679E-05 2.17108E-04 None 0 0 None 0 1.6469E-04 4.58014E-05 3.2991E-05 1.60339E-04
P/Q 21891 Ig-125 26 rs397517662 0.986 -0.142 1.0 D 0.759 0.733 0.763579139685 gnomAD-2.1.1 4.06E-06 None None None None I None 0 2.91E-05 None 0 0 None 0 None 0 0 0
P/Q 21891 Ig-125 26 rs397517662 0.986 -0.142 1.0 D 0.759 0.733 0.763579139685 gnomAD-4.0.0 1.36979E-06 None None None None I None 0 4.48169E-05 None 0 0 None 0 0 0 0 0
P/S 21891 Ig-125 26 None 0.9887 None 1.0 D 0.745 0.744 0.59105502098 gnomAD-4.0.0 6.84839E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99993E-07 0 0
P/T 21891 Ig-125 26 rs1446139113 0.9706 -0.265 1.0 D 0.745 0.752 0.759977468783 gnomAD-2.1.1 7.19E-06 None None None None I None 4.15E-05 0 None 0 0 None 0 None 0 7.89E-06 0
P/T 21891 Ig-125 26 rs1446139113 0.9706 -0.265 1.0 D 0.745 0.752 0.759977468783 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/T 21891 Ig-125 26 rs1446139113 0.9706 -0.265 1.0 D 0.745 0.752 0.759977468783 gnomAD-4.0.0 1.36462E-05 None None None None I None 2.67358E-05 0 None 0 0 None 0 0 1.69623E-05 0 0
P/L 22289 Ig-126 25 rs751203353 0.9235 -0.187 1.0 D 0.722 0.72 0.773713791686 gnomAD-2.1.1 4.04E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/L 22289 Ig-126 25 rs751203353 0.9235 -0.187 1.0 D 0.722 0.72 0.773713791686 gnomAD-4.0.0 1.59339E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43357E-05 0
P/H 22975 Ig-128 26 rs778464451 0.9798 -0.558 1.0 D 0.787 0.761 None gnomAD-2.1.1 1.21E-05 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 8.9E-06 1.66834E-04
P/H 22975 Ig-128 26 rs778464451 0.9798 -0.558 1.0 D 0.787 0.761 None gnomAD-3.1.2 6.6E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/H 22975 Ig-128 26 rs778464451 0.9798 -0.558 1.0 D 0.787 0.761 None gnomAD-4.0.0 9.92482E-06 None None None None I None 0 1.67023E-05 None 0 0 None 0 1.64636E-04 1.10237E-05 0 1.60231E-05
P/L 22975 Ig-128 26 None 0.9423 None 1.0 D 0.762 0.738 0.874729657411 gnomAD-4.0.0 6.847E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99795E-07 0 0
P/R 22975 Ig-128 26 rs778464451 0.9752 None 1.0 D 0.797 0.782 0.806807560233 gnomAD-3.1.2 6.6E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/R 22975 Ig-128 26 rs778464451 0.9752 None 1.0 D 0.797 0.782 0.806807560233 gnomAD-4.0.0 6.59517E-06 None None None None I None 2.42272E-05 0 None 0 0 None 0 0 0 0 0
P/T 22975 Ig-128 26 rs1218001244 0.9529 -0.72 1.0 D 0.736 0.762 0.764784440165 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/T 22975 Ig-128 26 rs1218001244 0.9529 -0.72 1.0 D 0.736 0.762 0.764784440165 gnomAD-4.0.0 1.5939E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43365E-05 0
P/L 23372 Ig-129 28 rs1709955188 0.8892 None 1.0 D 0.781 0.685 0.864968170662 gnomAD-4.0.0 1.59332E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86293E-06 0 0
P/L 23661 Ig-130 25 rs1060500459 0.968 -0.035 1.0 D 0.686 0.741 0.691170790121 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.98E-06 0
P/L 23661 Ig-130 25 rs1060500459 0.968 -0.035 1.0 D 0.686 0.741 0.691170790121 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/L 23661 Ig-130 25 rs1060500459 0.968 -0.035 1.0 D 0.686 0.741 0.691170790121 gnomAD-4.0.0 1.24041E-05 None None None None I None 0 1.66967E-05 None 0 0 None 0 0 1.44159E-05 2.19969E-05 0
P/S 23661 Ig-130 25 rs763795097 0.9918 -0.122 1.0 D 0.693 0.76 0.578198000816 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 3.29E-05 None 0 0 0
P/S 23661 Ig-130 25 rs763795097 0.9918 -0.122 1.0 D 0.693 0.76 0.578198000816 gnomAD-4.0.0 3.18747E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.87002E-05 0
P/L 24057 Ig-131 29 rs781601295 0.8513 -0.49 1.0 D 0.779 0.688 0.898687159605 gnomAD-2.1.1 4.03E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/Q 24057 Ig-131 29 None 0.9606 None 1.0 D 0.8 0.694 0.813645464229 gnomAD-4.0.0 6.84388E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99594E-07 0 0
P/H 24456 Ig-132 26 None 0.991 None 1.0 D 0.761 0.69 0.868472475781 gnomAD-4.0.0 1.59187E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85951E-06 0 0
P/R 24456 Ig-132 26 None 0.9858 None 1.0 D 0.76 0.698 0.86712314379 gnomAD-4.0.0 1.59187E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85951E-06 0 0
P/L 25139 Ig-134 29 rs771430495 0.9628 -0.152 1.0 D 0.779 0.747 0.856178836396 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/L 25139 Ig-134 29 rs771430495 0.9628 -0.152 1.0 D 0.779 0.747 0.856178836396 gnomAD-4.0.0 2.73714E-06 None None None None I None 0 0 None 0 0 None 0 0 3.59829E-06 0 0
P/S 25139 Ig-134 29 rs1462179644 0.9912 -0.8 1.0 D 0.763 0.761 0.68571362967 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/S 25139 Ig-134 29 rs1462179644 0.9912 -0.8 1.0 D 0.763 0.761 0.68571362967 gnomAD-4.0.0 1.59164E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85927E-06 0 0
P/R 25825 Ig-136 28 rs1177838501 0.9847 -0.165 1.0 D 0.771 0.638 0.844690456794 gnomAD-2.1.1 6.37E-05 None None None None I None 0 0 None 0 0 None 0 None 0 1.29668E-04 0
P/R 25825 Ig-136 28 rs1177838501 0.9847 -0.165 1.0 D 0.771 0.638 0.844690456794 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/R 25825 Ig-136 28 rs1177838501 0.9847 -0.165 1.0 D 0.771 0.638 0.844690456794 gnomAD-4.0.0 1.31537E-05 None None None None I None 0 0 None 0 0 None 0 0 2.94152E-05 0 0
P/S 25825 Ig-136 28 None 0.9924 None 1.0 D 0.733 0.634 0.685599082871 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 26221 Ig-137 29 rs912454417 0.97 None 1.0 D 0.804 0.776 0.785369063986 gnomAD-3.1.2 1.97E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 0 0 0
P/L 26221 Ig-137 29 rs912454417 0.97 None 1.0 D 0.804 0.776 0.785369063986 gnomAD-4.0.0 3.71991E-06 None None None None I None 6.67985E-05 0 None 0 0 None 0 0 0 0 1.6019E-05
P/R 26221 Ig-137 29 None 0.9889 None 1.0 D 0.817 0.777 0.701389159433 gnomAD-4.0.0 2.05348E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69903E-06 0 0
P/T 26221 Ig-137 29 rs1421106206 0.9833 None 1.0 D 0.804 0.81 0.65411270277 gnomAD-4.0.0 4.10706E-06 None None None None I None 0 0 None 0 0 None 0 0 5.3982E-06 0 0
P/L 26620 Ig-138 27 rs1260392231 0.9525 None 1.0 D 0.761 0.728 0.891535782347 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/L 26620 Ig-138 27 rs1260392231 0.9525 None 1.0 D 0.761 0.728 0.891535782347 gnomAD-4.0.0 3.04525E-06 None None None None I None 3.49724E-05 0 None 0 0 None 0 0 0 0 3.40252E-05
P/Q 26907 Ig-139 28 rs375693686 0.977 -0.369 1.0 D 0.788 0.818 None gnomAD-2.1.1 2.14E-05 None None None None I None 2.4818E-04 0 None 0 0 None 0 None 0 0 0
P/Q 26907 Ig-139 28 rs375693686 0.977 -0.369 1.0 D 0.788 0.818 None gnomAD-3.1.2 5.26E-05 None None None None I None 1.69131E-04 6.56E-05 0 0 0 None 0 0 0 0 0
P/Q 26907 Ig-139 28 rs375693686 0.977 -0.369 1.0 D 0.788 0.818 None gnomAD-4.0.0 1.1157E-05 None None None None I None 2.27151E-04 1.66806E-05 None 0 0 None 0 0 0 0 0
P/S 26907 Ig-139 28 None 0.9836 None 1.0 D 0.759 0.825 0.626257759281 gnomAD-4.0.0 1.36865E-06 None None None None I None 0 0 None 0 0 None 0 0 1.79913E-06 0 0
P/T 26907 Ig-139 28 rs776780869 0.9607 -0.409 1.0 D 0.755 0.837 0.678982705601 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/T 26907 Ig-139 28 rs776780869 0.9607 -0.409 1.0 D 0.755 0.837 0.678982705601 gnomAD-4.0.0 1.36865E-06 None None None None I None 0 0 None 0 0 None 0 0 0 2.31916E-05 0
P/L 27303 Ig-140 26 None 0.9657 None 1.0 D 0.772 0.747 0.75814979803 gnomAD-4.0.0 2.05314E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69841E-06 0 0
P/R 27303 Ig-140 26 None 0.9859 None 1.0 D 0.798 0.748 0.604839314244 gnomAD-4.0.0 6.8438E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99471E-07 0 0
P/Q 27703 Ig-141 28 None 0.9785 None 1.0 D 0.791 0.704 0.777365078794 gnomAD-4.0.0 1.59151E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85884E-06 0 0
P/S 27990 Ig-142 28 None 0.9588 None 1.0 D 0.719 0.583 0.620635632974 gnomAD-4.0.0 1.20035E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31253E-06 0 0
P/L 28782 Ig-144 28 rs561319491 0.9474 -0.181 1.0 D 0.759 0.561 None gnomAD-2.1.1 1.65E-05 None None None None I None 6.47E-05 0 None 0 0 None 0 None 0 2.71E-05 0
P/L 28782 Ig-144 28 rs561319491 0.9474 -0.181 1.0 D 0.759 0.561 None gnomAD-3.1.2 3.29E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 5.88E-05 0 0
P/L 28782 Ig-144 28 rs561319491 0.9474 -0.181 1.0 D 0.759 0.561 None 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 0 1E-03 None None None 0 None
P/L 28782 Ig-144 28 rs561319491 0.9474 -0.181 1.0 D 0.759 0.561 None gnomAD-4.0.0 2.61359E-05 None None None None I None 1.33422E-05 0 None 0 0 None 0 0 3.39778E-05 0 1.60694E-05
P/Q 28782 Ig-144 28 None 0.981 -0.395 1.0 D 0.769 0.591 0.678050635466 gnomAD-2.1.1 4.12E-06 None None None None I None 0 0 None 0 0 None 0 None 0 9.03E-06 0
P/Q 28782 Ig-144 28 None 0.981 -0.395 1.0 D 0.769 0.591 0.678050635466 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/Q 28782 Ig-144 28 None 0.981 -0.395 1.0 D 0.769 0.591 0.678050635466 gnomAD-4.0.0 1.30689E-05 None None None None I None 0 0 None 0 0 None 0 0 1.69888E-05 0 1.60751E-05
P/R 28782 Ig-144 28 rs561319491 0.9732 0.162 1.0 D 0.789 0.582 0.712739669407 gnomAD-2.1.1 4.12E-06 None None None None I None 0 0 None 0 0 None 3.39E-05 None 0 0 0
P/R 28782 Ig-144 28 rs561319491 0.9732 0.162 1.0 D 0.789 0.582 0.712739669407 gnomAD-4.0.0 6.87399E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.17233E-05 0
P/L 29468 Ig-146 25 rs747441311 0.9208 0.079 1.0 D 0.755 0.71 0.873541437591 gnomAD-2.1.1 2.01E-05 None None None None I None 0 0 None 0 0 None 6.54E-05 None 0 2.67E-05 0
P/L 29468 Ig-146 25 rs747441311 0.9208 0.079 1.0 D 0.755 0.71 0.873541437591 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 2.07469E-04 0
P/L 29468 Ig-146 25 rs747441311 0.9208 0.079 1.0 D 0.755 0.71 0.873541437591 gnomAD-4.0.0 9.91551E-06 None None None None I None 0 0 None 0 0 None 0 0 7.62823E-06 5.49028E-05 3.20256E-05
P/R 29468 Ig-146 25 rs747441311 0.9735 0.288 1.0 D 0.773 0.722 0.803054873015 gnomAD-2.1.1 4.03E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/R 29468 Ig-146 25 rs747441311 0.9735 0.288 1.0 D 0.773 0.722 0.803054873015 gnomAD-3.1.2 1.31E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/R 29468 Ig-146 25 rs747441311 0.9735 0.288 1.0 D 0.773 0.722 0.803054873015 gnomAD-4.0.0 2.47888E-06 None None None None I None 4.00534E-05 0 None 0 0 None 0 0 0 0 1.60128E-05
P/S 29468 Ig-146 25 rs769270365 0.9826 -0.035 1.0 D 0.744 0.775 0.620317764101 gnomAD-2.1.1 4.03E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/S 29468 Ig-146 25 rs769270365 0.9826 -0.035 1.0 D 0.744 0.775 0.620317764101 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 29867 Ig-147 26 rs1163231523 0.8757 -0.365 1.0 D 0.768 0.719 0.804401214385 gnomAD-2.1.1 4.09E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/L 29867 Ig-147 26 rs1163231523 0.8757 -0.365 1.0 D 0.768 0.719 0.804401214385 gnomAD-4.0.0 1.60561E-06 None None None None I None 0 2.28676E-05 None 0 0 None 0 0 0 0 0
P/R 29867 Ig-147 26 rs1163231523 0.9482 -0.039 1.0 D 0.793 0.735 0.735466501022 gnomAD-2.1.1 3.18E-05 None None None None I None 1.14732E-04 0 None 0 0 None 0 None 0 0 0
P/R 29867 Ig-147 26 rs1163231523 0.9482 -0.039 1.0 D 0.793 0.735 0.735466501022 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/R 29867 Ig-147 26 rs1163231523 0.9482 -0.039 1.0 D 0.793 0.735 0.735466501022 gnomAD-4.0.0 6.5697E-06 None None None None I None 2.41185E-05 0 None 0 0 None 0 0 0 0 0
P/H 30159 Ig-148 28 rs1699807023 0.9856 None 1.0 D 0.719 0.656 0.746219950608 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/H 30159 Ig-148 28 rs1699807023 0.9856 None 1.0 D 0.719 0.656 0.746219950608 gnomAD-4.0.0 6.57436E-06 None None None None I None 2.41499E-05 0 None 0 0 None 0 0 0 0 0
P/L 30554 Ig-149 23 rs1698777400 0.9429 None 1.0 D 0.739 0.73 0.882422999392 gnomAD-4.0.0 1.43684E-05 None None None None I None 0 0 None 0 0 None 0 0 1.88892E-05 0 0
P/Q 30554 Ig-149 23 None 0.9779 None 1.0 D 0.726 0.751 0.794492043152 gnomAD-4.0.0 6.84211E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99486E-07 0 0
P/L 30953 Ig-150 27 None 0.9267 None 1.0 D 0.753 0.689 0.798201095406 gnomAD-4.0.0 1.59255E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
P/L 31243 Ig-151 26 None 0.7218 None 1.0 D 0.776 0.702 0.703604667544 gnomAD-4.0.0 1.59116E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85793E-06 0 0
P/S 31243 Ig-151 26 rs757118302 0.8922 -0.02 1.0 D 0.763 0.68 0.62230568396 gnomAD-2.1.1 2.01E-05 None None None None I None 0 1.16036E-04 None 0 0 None 0 None 0 0 1.65782E-04
P/S 31243 Ig-151 26 rs757118302 0.8922 -0.02 1.0 D 0.763 0.68 0.62230568396 gnomAD-3.1.2 6.57E-06 None None None None I None 0 6.55E-05 0 0 0 None 0 0 0 0 0
P/S 31243 Ig-151 26 rs757118302 0.8922 -0.02 1.0 D 0.763 0.68 0.62230568396 gnomAD-4.0.0 8.96783E-06 None None None None I None 0 1.01723E-04 None 0 0 None 0 2.24215E-04 0 0 0
P/L 32042 Ig-153 26 rs879110168 0.8182 None 0.946 D 0.712 0.676 None gnomAD-4.0.0 2.73713E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69857E-06 0 1.65678E-05
P/L 32334 Ig-154 28 rs748395939 0.8421 0.004 1.0 D 0.745 0.693 0.797824397609 gnomAD-2.1.1 1.21E-05 None None None None I None 0 0 None 0 5.57E-05 None 0 None 0 1.79E-05 0
P/L 32334 Ig-154 28 rs748395939 0.8421 0.004 1.0 D 0.745 0.693 0.797824397609 gnomAD-4.0.0 2.05259E-06 None None None None I None 0 0 None 0 2.51927E-05 None 0 0 1.79893E-06 0 0
P/R 32334 Ig-154 28 rs748395939 0.9402 None 1.0 D 0.767 0.702 0.661616411291 gnomAD-4.0.0 4.78938E-06 None None None None I None 0 0 None 0 0 None 0 0 6.29624E-06 0 0
P/H 33128 Ig-156 28 rs1457575286 0.99 None 1.0 D 0.819 0.642 0.698937693345 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/H 33128 Ig-156 28 rs1457575286 0.99 None 1.0 D 0.819 0.642 0.698937693345 gnomAD-4.0.0 6.5735E-06 None None None None I None 2.41383E-05 0 None 0 0 None 0 0 0 0 0
P/L 33128 Ig-156 28 None 0.9663 None 1.0 D 0.783 0.634 0.802141629741 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/S 33224 Ig-157 22 rs879139495 0.9835 -2.58 1.0 D 0.763 0.703 None gnomAD-2.1.1 7.14E-06 None None None None N None 0 0 None 0 0 None 0 None 0 7.8E-06 1.40607E-04
P/S 33224 Ig-157 22 rs879139495 0.9835 -2.58 1.0 D 0.763 0.703 None gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 33224 Ig-157 22 rs879139495 0.9835 -2.58 1.0 D 0.763 0.703 None gnomAD-4.0.0 6.4062E-06 None None None None N None 0 0 None 0 0 None 0 0 7.17927E-06 2.68068E-05 0
P/Q 33523 Ig-158 28 rs794729558 0.9866 None 1.0 D 0.793 0.717 0.633466640759 gnomAD-4.0.0 3.18402E-06 None None None None I None 0 0 None 0 0 None 0 4.82393E-04 0 0 0
P/L 33623 Ig-159 28 rs1199682198 0.9895 -0.368 1.0 D 0.757 0.735 0.856589233873 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.89E-06 0
P/L 33623 Ig-159 28 rs1199682198 0.9895 -0.368 1.0 D 0.757 0.735 0.856589233873 gnomAD-4.0.0 1.59158E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85842E-06 0 0
Q/P 34164 Ig-160 28 None 0.1154 None 0.106 N 0.487 0.191 0.188950314367 gnomAD-4.0.0 1.36832E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79883E-06 0 0
Q/R 34164 Ig-160 28 rs1329503424 0.113 0.279 0.012 N 0.343 0.134 0.191931220699 gnomAD-2.1.1 4.02E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
Q/R 34164 Ig-160 28 rs1329503424 0.113 0.279 0.012 N 0.343 0.134 0.191931220699 gnomAD-4.0.0 6.84159E-07 None None None None N None 0 2.23604E-05 None 0 0 None 0 0 0 0 0
P/A 34285 Ig-161 28 rs794729563 0.9335 None 1.0 N 0.727 0.549 0.299770980665 gnomAD-4.0.0 3.42079E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49707E-06 0 0
P/L 34285 Ig-161 28 rs1690211632 0.966 None 1.0 D 0.747 0.623 0.53754225682 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 34285 Ig-161 28 rs1690211632 0.966 None 1.0 D 0.747 0.623 0.53754225682 gnomAD-4.0.0 6.57272E-06 None None None None I None 0 0 None 0 0 None 0 0 1.46998E-05 0 0
P/S 34285 Ig-161 28 None 0.9785 None 1.0 N 0.751 0.586 0.341460817117 gnomAD-4.0.0 3.42079E-06 None None None None I None 0 0 None 0 0 None 0 0 4.49707E-06 0 0
P/T 34285 Ig-161 28 None 0.9452 None 1.0 D 0.744 0.608 0.420080204436 gnomAD-4.0.0 6.84158E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.15931E-05 0
P/L 34390 Ig-162 28 rs1163886514 0.9082 -0.309 1.0 D 0.751 0.778 0.801125762009 gnomAD-2.1.1 4.02E-06 None None None None I None 6.47E-05 0 None 0 0 None 0 None 0 0 0
P/L 34390 Ig-162 28 rs1163886514 0.9082 -0.309 1.0 D 0.751 0.778 0.801125762009 gnomAD-3.1.2 1.31E-05 None None None None I None 2.41E-05 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 34390 Ig-162 28 rs1163886514 0.9082 -0.309 1.0 D 0.751 0.778 0.801125762009 gnomAD-4.0.0 6.40576E-06 None None None None I None 5.07614E-05 0 None 0 0 None 0 0 4.78595E-06 0 0
P/R 34969 Ig-163 28 rs2154133728 0.9903 None 1.0 D 0.807 0.752 0.809714403538 gnomAD-4.0.0 4.77268E-06 None None None None I None 0 6.85902E-05 None 0 0 None 0 0 0 0 0
P/T 34969 Ig-163 28 rs1256480602 0.9611 None 1.0 D 0.763 0.759 0.75516907234 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/T 34969 Ig-163 28 rs1256480602 0.9611 None 1.0 D 0.763 0.759 0.75516907234 gnomAD-4.0.0 6.57194E-06 None None None None I None 2.41324E-05 0 None 0 0 None 0 0 0 0 0
P/L 35156 Ig-164 28 rs538363206 0.7704 0.254 1.0 D 0.744 0.686 0.88459850544 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.54E-05 0
P/L 35156 Ig-164 28 rs538363206 0.7704 0.254 1.0 D 0.744 0.686 0.88459850544 gnomAD-4.0.0 9.5779E-06 None None None None I None 0 0 None 0 0 None 0 0 6.29575E-06 4.63725E-05 4.96903E-05
P/R 35156 Ig-164 28 rs538363206 0.8823 0.388 1.0 D 0.761 0.703 0.80067929644 gnomAD-2.1.1 1.61E-05 None None None None I None 0 0 None 0 1.66908E-04 None 3.27E-05 None 0 0 0
P/R 35156 Ig-164 28 rs538363206 0.8823 0.388 1.0 D 0.761 0.703 0.80067929644 gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 3.84911E-04 None 0 0 0 0 0
P/R 35156 Ig-164 28 rs538363206 0.8823 0.388 1.0 D 0.761 0.703 0.80067929644 1000 genomes 1.99681E-04 None None None None I None 0 0 None None 1E-03 0 None None None 0 None
P/R 35156 Ig-164 28 rs538363206 0.8823 0.388 1.0 D 0.761 0.703 0.80067929644 gnomAD-4.0.0 4.33723E-06 None None None None I None 0 0 None 0 1.11398E-04 None 0 0 0 0 3.20061E-05
R/G 35313 Ig-165 28 None 0.063 None 0.001 N 0.187 0.092 0.208000267992 gnomAD-4.0.0 2.40064E-06 None None None None I None 0 0 None 0 0 None 0 0 2.625E-06 0 0
R/S 35313 Ig-165 28 rs1688720188 0.0799 None None N 0.097 0.1 0.0716867268079 gnomAD-4.0.0 6.84136E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99392E-07 0 0
P/R 35447 Ig-166 28 None 0.7041 None 0.986 D 0.571 0.627 0.565865824572 gnomAD-4.0.0 8.23794E-06 None None None None I None 0 0 None 0 0 None 0 0 1.08255E-05 0 0
P/S 35447 Ig-166 28 None 0.5986 None 0.271 D 0.254 0.552 0.379366414296 gnomAD-4.0.0 2.05894E-06 None None None None I None 0 0 None 0 0 None 0 0 2.70579E-06 0 0
P/S 35729 Ig-168 28 None 0.7665 None 1.0 D 0.748 0.815 0.65692934574 gnomAD-4.0.0 1.59631E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86824E-06 0 0
P/A 35924 Ig-169 28 rs752429003 0.6148 -1.238 0.767 D 0.321 0.552 0.438064232554 gnomAD-2.1.1 4.02E-06 None None None -0.379(OBSL1) -0.417(OBSCN) N None 0 0 None 0 0 None 0 None 0 8.86E-06 0
P/A 35924 Ig-169 28 rs752429003 0.6148 -1.238 0.767 D 0.321 0.552 0.438064232554 gnomAD-4.0.0 1.20032E-06 None None None -0.379(OBSL1) -0.417(OBSCN) N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.