Structural position:
- Domain Type: Ig
- Aligned Position: 47
- Secondary Structure Element: e
- Secondary Structure Region: β-strand C
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S/N | 38 |
Ig-1 |
33 | None | 0.2395 | None | 0.006 | N | 0.355 | 0.176 | 0.191931220699 | gnomAD-4.0.0 | 1.59066E-06 | None | None | None | -0.686(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02151E-05 |
| S/R | 38 |
Ig-1 |
33 | None | 0.6374 | None | 0.995 | N | 0.69 | 0.669 | 0.594650670498 | gnomAD-4.0.0 | 1.59063E-06 | None | None | None | -0.206(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0217E-05 |
| T/A | 975 |
Ig-3 |
33 | rs2092909709 |
0.1312 | None | None | N | 0.165 | 0.216 | 0.238705975628 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14422E-04 | 0 |
| T/A | 975 |
Ig-3 |
33 | rs2092909709 |
0.1312 | None | None | N | 0.165 | 0.216 | 0.238705975628 | gnomAD-4.0.0 | 3.84149E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.02015E-05 | 0 |
| A/S | 1323 |
Ig-5 |
33 | rs555618887 |
0.2135 | -0.71 | 0.978 | N | 0.454 | 0.262 | 0.229264304666 | gnomAD-2.1.1 | 5.6E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.57905E-04 | None | 0 | 0 | 0 |
| A/S | 1323 |
Ig-5 |
33 | rs555618887 |
0.2135 | -0.71 | 0.978 | N | 0.454 | 0.262 | 0.229264304666 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14422E-04 | 0 |
| A/S | 1323 |
Ig-5 |
33 | rs555618887 |
0.2135 | -0.71 | 0.978 | N | 0.454 | 0.262 | 0.229264304666 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| A/S | 1323 |
Ig-5 |
33 | rs555618887 |
0.2135 | -0.71 | 0.978 | N | 0.454 | 0.262 | 0.229264304666 | gnomAD-4.0.0 | 2.97443E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69501E-06 | 4.8323E-04 | 3.20031E-05 |
| A/T | 1323 |
Ig-5 |
33 | rs555618887 |
0.3175 | -0.331 | 0.733 | N | 0.349 | 0.266 | 0.230578612272 | gnomAD-2.1.1 | 1.6E-05 | None | None | None | None | N | None | 0 | 1.16016E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 1323 |
Ig-5 |
33 | rs555618887 |
0.3175 | -0.331 | 0.733 | N | 0.349 | 0.266 | 0.230578612272 | gnomAD-4.0.0 | 2.737E-06 | None | None | None | None | N | None | 0 | 8.95015E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 1323 |
Ig-5 |
33 | rs774954394 |
0.3835 | 0.764 | 0.733 | N | 0.358 | 0.408 | 0.408988072059 | gnomAD-2.1.1 | 4E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/V | 1323 |
Ig-5 |
33 | rs774954394 |
0.3835 | 0.764 | 0.733 | N | 0.358 | 0.408 | 0.408988072059 | gnomAD-4.0.0 | 1.59154E-06 | None | None | None | None | N | None | 0 | 2.28781E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 1588 |
Ig-7 |
33 | rs1561301529 |
0.8783 | None | 0.928 | N | 0.573 | 0.319 | 0.610589977033 | gnomAD-4.0.0 | 1.59062E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02151E-05 |
| V/I | 1588 |
Ig-7 |
33 | rs1375582195 |
0.1953 | None | 0.039 | N | 0.308 | 0.121 | 0.470318359215 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/I | 1588 |
Ig-7 |
33 | rs1375582195 |
0.1953 | None | 0.039 | N | 0.308 | 0.121 | 0.470318359215 | gnomAD-4.0.0 | 3.09789E-06 | None | None | None | None | N | None | 2.66937E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47471E-07 | 2.19553E-05 | 0 |
| V/L | 1588 |
Ig-7 |
33 | rs1375582195 |
0.8068 | -0.272 | 0.476 | D | 0.494 | 0.223 | 0.47185959272 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14811E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/L | 1588 |
Ig-7 |
33 | rs1375582195 |
0.8068 | -0.272 | 0.476 | D | 0.494 | 0.223 | 0.47185959272 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/L | 1588 |
Ig-7 |
33 | rs1375582195 |
0.8068 | -0.272 | 0.476 | D | 0.494 | 0.223 | 0.47185959272 | gnomAD-4.0.0 | 6.56953E-06 | None | None | None | None | N | None | 2.41243E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 1737 |
Ig-8 |
35 | None | 0.3935 | None | 0.999 | D | 0.504 | 0.416 | 0.223146558224 | gnomAD-4.0.0 | 1.59066E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85647E-06 | 0 | 0 |
| E/G | 1737 |
Ig-8 |
35 | rs766132240 |
0.8302 | -0.932 | 1.0 | D | 0.73 | 0.684 | 0.645789463786 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/G | 1737 |
Ig-8 |
35 | rs766132240 |
0.8302 | -0.932 | 1.0 | D | 0.73 | 0.684 | 0.645789463786 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/G | 1737 |
Ig-8 |
35 | rs766132240 |
0.8302 | -0.932 | 1.0 | D | 0.73 | 0.684 | 0.645789463786 | gnomAD-4.0.0 | 2.56119E-06 | None | None | None | None | N | None | 1.69085E-05 | 1.69492E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 1873 |
Ig-9 |
33 | rs762273184 |
0.1149 | -0.549 | 0.905 | N | 0.381 | 0.22 | 0.141422826196 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| N/S | 1873 |
Ig-9 |
33 | rs762273184 |
0.1149 | -0.549 | 0.905 | N | 0.381 | 0.22 | 0.141422826196 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/S | 1873 |
Ig-9 |
33 | rs762273184 |
0.1149 | -0.549 | 0.905 | N | 0.381 | 0.22 | 0.141422826196 | gnomAD-4.0.0 | 6.5684E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46968E-05 | 0 | 0 |
| K/R | 2206 |
Ig-11 |
33 | None | 0.0916 | None | 0.999 | N | 0.587 | 0.428 | 0.339316883193 | gnomAD-4.0.0 | 1.59074E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85678E-06 | 0 | 0 |
| V/I | 2387 |
Ig-13 |
32 | rs377691143 |
0.0581 | -0.383 | 0.008 | N | 0.241 | 0.044 | None | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 1.98768E-04 | 1.08873E-04 | None | 6.53E-05 | None | 0 | 1.76E-05 | 0 |
| V/I | 2387 |
Ig-13 |
32 | rs377691143 |
0.0581 | -0.383 | 0.008 | N | 0.241 | 0.044 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 2.88351E-04 | 0 | None | 0 | 0 | 4.41E-05 | 2.07211E-04 | 0 |
| V/I | 2387 |
Ig-13 |
32 | rs377691143 |
0.0581 | -0.383 | 0.008 | N | 0.241 | 0.044 | None | gnomAD-4.0.0 | 1.85877E-05 | None | None | None | None | N | None | 1.33472E-05 | 0 | None | 1.01338E-04 | 4.45593E-05 | None | 0 | 0 | 1.52543E-05 | 3.29366E-05 | 4.80108E-05 |
| E/K | 2651 |
Ig-16 |
31 | rs770388400 |
0.1099 | -1.176 | 0.019 | N | 0.162 | 0.257 | 0.314417295294 | gnomAD-2.1.1 | 2.39E-05 | None | None | None | None | N | None | 1.23031E-04 | 0 | None | 0 | 0 | None | 9.8E-05 | None | 0 | 0 | 1.63185E-04 |
| E/K | 2651 |
Ig-16 |
31 | rs770388400 |
0.1099 | -1.176 | 0.019 | N | 0.162 | 0.257 | 0.314417295294 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 2651 |
Ig-16 |
31 | rs770388400 |
0.1099 | -1.176 | 0.019 | N | 0.162 | 0.257 | 0.314417295294 | gnomAD-4.0.0 | 1.85882E-05 | None | None | None | None | N | None | 4.00374E-05 | 0 | None | 0 | 2.22906E-05 | None | 0 | 1.6442E-04 | 1.52545E-05 | 5.48992E-05 | 3.20092E-05 |
| K/R | 3000 |
Ig-20 |
32 | None | 0.1081 | None | 0.999 | N | 0.593 | 0.416 | 0.314417295294 | gnomAD-4.0.0 | 1.59063E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85651E-06 | 0 | 0 |
| H/L | 3178 |
Ig-22 |
32 | rs1334781459 |
0.1943 | -0.99 | 0.183 | N | 0.475 | 0.283 | 0.474722520063 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| H/L | 3178 |
Ig-22 |
32 | rs1334781459 |
0.1943 | -0.99 | 0.183 | N | 0.475 | 0.283 | 0.474722520063 | gnomAD-4.0.0 | 4.78863E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39581E-06 | 0 | 1.65596E-05 |
| H/P | 3178 |
Ig-22 |
32 | None | 0.8323 | None | 0.523 | N | 0.552 | 0.405 | 0.356897458496 | gnomAD-4.0.0 | 6.8409E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99302E-07 | 0 | 0 |
| H/R | 3178 |
Ig-22 |
32 | rs1334781459 |
0.0897 | -1.106 | None | N | 0.241 | 0.297 | 0.0954503805726 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| H/R | 3178 |
Ig-22 |
32 | rs1334781459 |
0.0897 | -1.106 | None | N | 0.241 | 0.297 | 0.0954503805726 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| H/R | 3178 |
Ig-22 |
32 | rs1334781459 |
0.0897 | -1.106 | None | N | 0.241 | 0.297 | 0.0954503805726 | gnomAD-4.0.0 | 1.23919E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69491E-06 | 0 | 0 |
| S/A | 3271 |
Ig-23 |
33 | rs556720151 |
0.0996 | -0.448 | None | N | 0.225 | 0.172 | 0.193865811164 | gnomAD-2.1.1 | 3.54E-05 | None | None | None | None | N | None | 4.00481E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/A | 3271 |
Ig-23 |
33 | rs556720151 |
0.0996 | -0.448 | None | N | 0.225 | 0.172 | 0.193865811164 | gnomAD-3.1.2 | 1.11705E-04 | None | None | None | None | N | None | 4.10133E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 3271 |
Ig-23 |
33 | rs556720151 |
0.0996 | -0.448 | None | N | 0.225 | 0.172 | 0.193865811164 | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| S/A | 3271 |
Ig-23 |
33 | rs556720151 |
0.0996 | -0.448 | None | N | 0.225 | 0.172 | 0.193865811164 | gnomAD-4.0.0 | 1.73467E-05 | None | None | None | None | N | None | 3.46426E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.19949E-05 |
| S/F | 3271 |
Ig-23 |
33 | rs867536098 |
0.167 | -0.554 | None | N | 0.411 | 0.245 | 0.458013479912 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 2.89E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/F | 3271 |
Ig-23 |
33 | rs867536098 |
0.167 | -0.554 | None | N | 0.411 | 0.245 | 0.458013479912 | gnomAD-4.0.0 | 4.77164E-06 | None | None | None | None | N | None | 0 | 2.28645E-05 | None | 0 | 0 | None | 0 | 0 | 2.85657E-06 | 0 | 3.02151E-05 |
| S/P | 3271 |
Ig-23 |
33 | rs556720151 |
0.9468 | 0.043 | 0.295 | D | 0.572 | 0.477 | 0.319402600006 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| S/Y | 3271 |
Ig-23 |
33 | rs867536098 |
0.1679 | -0.271 | 0.093 | D | 0.589 | 0.363 | 0.489243007833 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.83E-06 | 0 |
| S/L | 3376 |
Ig-24 |
32 | rs781368765 |
0.1378 | 0.966 | 0.574 | N | 0.611 | 0.28 | 0.615590475704 | gnomAD-2.1.1 | 2.49E-05 | None | None | None | None | N | None | 2.00481E-04 | 2.83E-05 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/L | 3376 |
Ig-24 |
32 | rs781368765 |
0.1378 | 0.966 | 0.574 | N | 0.611 | 0.28 | 0.615590475704 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 1.20825E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 3376 |
Ig-24 |
32 | rs781368765 |
0.1378 | 0.966 | 0.574 | N | 0.611 | 0.28 | 0.615590475704 | gnomAD-4.0.0 | 9.29588E-06 | None | None | None | None | N | None | 1.60304E-04 | 1.66767E-05 | None | 0 | 0 | None | 0 | 0 | 8.47525E-07 | 1.09837E-05 | 0 |
| Q/R | 3497 |
Ig-25 |
33 | None | 0.1381 | None | None | None | None | 0.086 | None | gnomAD-4.0.0 | 1.59111E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85809E-06 | 0 | 0 |
| T/I | 3692 |
Ig-26 |
33 | rs767415803 |
0.1273 | 0.201 | None | None | None | 0.103 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65948E-04 |
| T/I | 3692 |
Ig-26 |
33 | rs767415803 |
0.1273 | 0.201 | None | None | None | 0.103 | None | gnomAD-4.0.0 | 1.71055E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.06874E-05 | 0 | 3.31312E-05 |
| T/N | 3692 |
Ig-26 |
33 | rs767415803 |
0.1612 | -0.707 | None | None | None | 0.147 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| T/N | 3692 |
Ig-26 |
33 | rs767415803 |
0.1612 | -0.707 | None | None | None | 0.147 | None | gnomAD-4.0.0 | 6.15799E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.09505E-06 | 0 | 0 |
| Q/L | 3852 |
Ig-27 |
33 | None | 0.212 | None | 0.801 | N | 0.542 | 0.287 | None | gnomAD-4.0.0 | 1.59123E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85832E-06 | 0 | 0 |
| T/A | 3970 |
Ig-28 |
33 | rs767950309 |
0.0575 | -0.871 | None | N | 0.18 | 0.084 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/A | 3970 |
Ig-28 |
33 | rs767950309 |
0.0575 | -0.871 | None | N | 0.18 | 0.084 | None | gnomAD-4.0.0 | 1.5911E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85791E-06 | 0 | 0 |
| T/I | 3970 |
Ig-28 |
33 | None | 0.0923 | None | None | N | 0.364 | 0.158 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/S | 4636 |
Ig-29 |
31 | rs773324490 |
0.0984 | -0.767 | 0.324 | N | 0.529 | 0.08 | None | gnomAD-2.1.1 | 2.5E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 3.08801E-04 | None | 0 | None | 0 | 0 | 0 |
| N/S | 4636 |
Ig-29 |
31 | rs773324490 |
0.0984 | -0.767 | 0.324 | N | 0.529 | 0.08 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 4636 |
Ig-29 |
31 | rs773324490 |
0.0984 | -0.767 | 0.324 | N | 0.529 | 0.08 | None | gnomAD-4.0.0 | 7.68673E-06 | None | None | None | None | N | None | 1.69039E-05 | 0 | None | 0 | 7.28403E-05 | None | 0 | 2.24215E-04 | 2.39295E-06 | 0 | 0 |
| I/N | 4827 |
Ig-31 |
33 | None | 0.2391 | None | 0.655 | N | 0.603 | 0.263 | 0.767856249327 | gnomAD-4.0.0 | 6.84205E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.52042E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/T | 4827 |
Ig-31 |
33 | None | 0.1845 | None | 0.003 | N | 0.278 | 0.205 | 0.583677480531 | gnomAD-4.0.0 | 6.84205E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99457E-07 | 0 | 0 |
| T/A | 4920 |
Ig-32 |
33 | rs1178136076 |
0.0736 | -0.839 | 0.001 | N | 0.169 | 0.101 | 0.139678290688 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 4920 |
Ig-32 |
33 | rs1178136076 |
0.0736 | -0.839 | 0.001 | N | 0.169 | 0.101 | 0.139678290688 | gnomAD-4.0.0 | 1.5913E-06 | None | None | None | None | N | None | 0 | 2.28655E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/K | 4920 |
Ig-32 |
33 | rs371455094 |
0.1667 | -0.649 | 0.408 | N | 0.493 | 0.266 | 0.273938319068 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/K | 4920 |
Ig-32 |
33 | rs371455094 |
0.1667 | -0.649 | 0.408 | N | 0.493 | 0.266 | 0.273938319068 | gnomAD-4.0.0 | 6.84233E-07 | None | None | None | None | N | None | 0 | 2.23654E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/M | 4920 |
Ig-32 |
33 | rs371455094 |
0.071 | 0.111 | 0.216 | N | 0.353 | 0.121 | None | gnomAD-2.1.1 | 7.14E-05 | None | None | None | None | N | None | 5.78752E-04 | 0 | None | 0 | 1.54099E-04 | None | 3.27E-05 | None | 0 | 1.56E-05 | 0 |
| T/M | 4920 |
Ig-32 |
33 | rs371455094 |
0.071 | 0.111 | 0.216 | N | 0.353 | 0.121 | None | gnomAD-3.1.2 | 1.24908E-04 | None | None | None | None | N | None | 4.58782E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/M | 4920 |
Ig-32 |
33 | rs371455094 |
0.071 | 0.111 | 0.216 | N | 0.353 | 0.121 | None | gnomAD-4.0.0 | 4.02826E-05 | None | None | None | None | N | None | 5.74206E-04 | 0 | None | 0 | 6.68866E-05 | None | 0 | 1.64474E-04 | 1.18663E-05 | 4.39174E-05 | 0 |
| T/A | 5014 |
Ig-33 |
34 | rs143093473 |
0.0997 | -0.932 | 0.64 | N | 0.577 | 0.235 | 0.317667799068 | gnomAD-2.1.1 | 6.05E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.90709E-04 | None | 0 | 0 | 0 |
| T/A | 5014 |
Ig-33 |
34 | rs143093473 |
0.0997 | -0.932 | 0.64 | N | 0.577 | 0.235 | 0.317667799068 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| T/A | 5014 |
Ig-33 |
34 | rs143093473 |
0.0997 | -0.932 | 0.64 | N | 0.577 | 0.235 | 0.317667799068 | gnomAD-4.0.0 | 2.35528E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.69534E-06 | 3.73356E-04 | 3.2039E-05 |
| T/I | 5014 |
Ig-33 |
34 | None | 0.1768 | None | 0.984 | N | 0.674 | 0.453 | 0.684344447183 | gnomAD-4.0.0 | 1.59202E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43299E-05 | 0 |
| T/S | 5014 |
Ig-33 |
34 | rs143093473 |
0.1099 | -1.252 | 0.103 | N | 0.431 | 0.093 | 0.226586394389 | gnomAD-2.1.1 | 9.67E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.39348E-03 | None | 0 | None | 0 | 0 | 0 |
| T/S | 5014 |
Ig-33 |
34 | rs143093473 |
0.1099 | -1.252 | 0.103 | N | 0.431 | 0.093 | 0.226586394389 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 9.64134E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 5014 |
Ig-33 |
34 | rs143093473 |
0.1099 | -1.252 | 0.103 | N | 0.431 | 0.093 | 0.226586394389 | 1000 genomes | 5.99042E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 3E-03 | 0 | None | None | None | 0 | None |
| T/S | 5014 |
Ig-33 |
34 | rs143093473 |
0.1099 | -1.252 | 0.103 | N | 0.431 | 0.093 | 0.226586394389 | gnomAD-4.0.0 | 2.41708E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.04218E-04 | None | 0 | 0 | 0 | 0 | 4.80415E-05 |
| S/I | 5107 |
Ig-34 |
33 | rs748973546 |
0.1226 | 0.643 | 0.317 | N | 0.595 | 0.395 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.5E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/I | 5107 |
Ig-34 |
33 | rs748973546 |
0.1226 | 0.643 | 0.317 | N | 0.595 | 0.395 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| S/I | 5107 |
Ig-34 |
33 | rs748973546 |
0.1226 | 0.643 | 0.317 | N | 0.595 | 0.395 | None | gnomAD-4.0.0 | 2.72695E-05 | None | None | None | None | N | None | 1.33472E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.64493E-05 | 0 | 0 |
| K/Q | 5293 |
Ig-36 |
33 | rs930814645 |
0.1258 | -0.912 | 0.998 | N | 0.643 | 0.36 | 0.357313475932 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14837E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/Q | 5293 |
Ig-36 |
33 | rs930814645 |
0.1258 | -0.912 | 0.998 | N | 0.643 | 0.36 | 0.357313475932 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/Q | 5293 |
Ig-36 |
33 | rs930814645 |
0.1258 | -0.912 | 0.998 | N | 0.643 | 0.36 | 0.357313475932 | gnomAD-4.0.0 | 2.56208E-06 | None | None | None | None | N | None | 3.38123E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 5293 |
Ig-36 |
33 | rs761945485 |
0.0764 | -0.291 | 0.994 | N | 0.549 | 0.236 | 0.419957187557 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 8.89E-06 | 0 |
| K/R | 5293 |
Ig-36 |
33 | rs761945485 |
0.0764 | -0.291 | 0.994 | N | 0.549 | 0.236 | 0.419957187557 | gnomAD-4.0.0 | 6.36491E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.57476E-06 | 1.43279E-05 | 0 |
| K/T | 5293 |
Ig-36 |
33 | None | 0.1696 | None | 0.998 | N | 0.681 | 0.373 | 0.547512163748 | gnomAD-4.0.0 | 1.59122E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85824E-06 | 0 | 0 |
| S/F | 5389 |
Ig-37 |
33 | rs780968460 |
0.1555 | -0.286 | 0.667 | N | 0.713 | 0.424 | 0.702110701905 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/F | 5389 |
Ig-37 |
33 | rs780968460 |
0.1555 | -0.286 | 0.667 | N | 0.713 | 0.424 | 0.702110701905 | gnomAD-4.0.0 | 3.18385E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85878E-06 | 1.43303E-05 | 0 |
| R/G | 5482 |
Ig-38 |
33 | rs1261601154 |
0.1313 | None | 0.055 | N | 0.581 | 0.348 | 0.434606191737 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/G | 5482 |
Ig-38 |
33 | rs1261601154 |
0.1313 | None | 0.055 | N | 0.581 | 0.348 | 0.434606191737 | gnomAD-4.0.0 | 2.47918E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39065E-06 | 0 | 0 |
| T/A | 5576 |
Ig-39 |
34 | rs769401892 |
0.0772 | -0.932 | 0.454 | N | 0.484 | 0.251 | 0.33085137897 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/R | 5576 |
Ig-39 |
34 | None | 0.0926 | None | 0.012 | N | 0.373 | 0.309 | 0.536851905119 | gnomAD-4.0.0 | 1.59124E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85822E-06 | 0 | 0 |
| T/I | 5669 |
Ig-40 |
33 | rs2080592409 |
0.1193 | None | 0.473 | N | 0.543 | 0.302 | 0.455173453901 | gnomAD-4.0.0 | 7.95684E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.38673E-04 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 5855 |
Ig-42 |
33 | None | 0.2155 | None | 0.027 | N | 0.551 | 0.205 | 0.282179105231 | gnomAD-4.0.0 | 2.05271E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69853E-06 | 0 | 0 |
| K/R | 5855 |
Ig-42 |
33 | rs772017452 |
0.0694 | -0.636 | None | N | 0.208 | 0.111 | 0.236278675362 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| K/R | 5855 |
Ig-42 |
33 | rs772017452 |
0.0694 | -0.636 | None | N | 0.208 | 0.111 | 0.236278675362 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 5855 |
Ig-42 |
33 | rs772017452 |
0.0694 | -0.636 | None | N | 0.208 | 0.111 | 0.236278675362 | gnomAD-4.0.0 | 2.56249E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.42495E-05 | None | 0 | 0 | 2.39329E-06 | 0 | 0 |
| K/N | 6044 |
Ig-44 |
33 | rs749108620 |
0.552 | -0.636 | 0.576 | N | 0.408 | 0.195 | 0.21737058555 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| K/N | 6044 |
Ig-44 |
33 | rs749108620 |
0.552 | -0.636 | 0.576 | N | 0.408 | 0.195 | 0.21737058555 | gnomAD-4.0.0 | 1.5931E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43464E-05 | 0 |
| K/Q | 6044 |
Ig-44 |
33 | rs1560783710 |
0.145 | None | 0.997 | N | 0.597 | 0.348 | 0.310458034454 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| K/Q | 6044 |
Ig-44 |
33 | rs1560783710 |
0.145 | None | 0.997 | N | 0.597 | 0.348 | 0.310458034454 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/Q | 6044 |
Ig-44 |
33 | rs1560783710 |
0.145 | None | 0.997 | N | 0.597 | 0.348 | 0.310458034454 | gnomAD-4.0.0 | 6.57358E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47024E-05 | 0 | 0 |
| K/T | 6044 |
Ig-44 |
33 | rs2080198775 |
0.1892 | None | 0.978 | N | 0.621 | 0.365 | 0.372446077551 | gnomAD-4.0.0 | 1.59318E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86076E-06 | 0 | 0 |
| S/F | 6138 |
Ig-45 |
34 | None | 0.1578 | None | 0.473 | N | 0.585 | 0.391 | 0.517765160837 | gnomAD-4.0.0 | 6.84262E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| S/Y | 6138 |
Ig-45 |
34 | rs727504477 |
0.16 | -0.123 | 0.01 | N | 0.417 | 0.336 | 0.468420198123 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/Y | 6138 |
Ig-45 |
34 | rs727504477 |
0.16 | -0.123 | 0.01 | N | 0.417 | 0.336 | 0.468420198123 | gnomAD-4.0.0 | 7.52688E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.89447E-06 | 0 | 0 |
| T/A | 6231 |
Ig-46 |
33 | None | 0.0864 | None | 0.174 | N | 0.523 | 0.26 | 0.252681307341 | gnomAD-4.0.0 | 1.36857E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79913E-06 | 0 | 0 |
| T/N | 6324 |
Ig-47 |
33 | None | 0.116 | None | 0.175 | N | 0.4 | 0.172 | 0.298745278005 | gnomAD-4.0.0 | 3.42357E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49911E-06 | 0 | 0 |
| T/S | 6324 |
Ig-47 |
33 | rs2079898671 |
0.0923 | None | 0.001 | N | 0.202 | 0.075 | 0.186928172975 | gnomAD-4.0.0 | 1.36943E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79965E-06 | 0 | 0 |
| K/E | 6417 |
Ig-48 |
33 | rs771838033 |
0.295 | -0.252 | 0.939 | D | 0.493 | 0.292 | None | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| K/E | 6417 |
Ig-48 |
33 | rs771838033 |
0.295 | -0.252 | 0.939 | D | 0.493 | 0.292 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| K/E | 6417 |
Ig-48 |
33 | rs771838033 |
0.295 | -0.252 | 0.939 | D | 0.493 | 0.292 | None | gnomAD-4.0.0 | 3.71904E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08644E-06 | 0 | 0 |
| K/T | 6417 |
Ig-48 |
33 | None | 0.1783 | None | 0.991 | N | 0.676 | 0.327 | 0.444706120422 | gnomAD-4.0.0 | 6.84403E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9963E-07 | 0 | 0 |
| V/A | 6700 |
Ig-51 |
34 | rs367635778 |
0.0971 | None | 0.005 | N | 0.322 | 0.074 | 0.468753983522 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| V/A | 6700 |
Ig-51 |
34 | rs367635778 |
0.0971 | None | 0.005 | N | 0.322 | 0.074 | 0.468753983522 | gnomAD-4.0.0 | 3.7196E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08718E-06 | 0 | 0 |
| V/L | 6700 |
Ig-51 |
34 | rs72648957 |
0.108 | -0.336 | 0.004 | N | 0.368 | 0.114 | 0.326074293725 | gnomAD-4.0.0 | 1.5928E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.861E-06 | 0 | 0 |
| V/I | 6793 |
Ig-52 |
33 | rs2079262565 |
0.0639 | None | None | N | 0.205 | 0.053 | 0.515490261806 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/P | 6886 |
Ig-53 |
33 | None | 0.7638 | None | 0.202 | D | 0.499 | 0.391 | 0.318828661733 | gnomAD-4.0.0 | 6.84516E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.5208E-05 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 6886 |
Ig-53 |
33 | None | 0.1159 | None | 0.025 | N | 0.369 | 0.263 | 0.132336055621 | gnomAD-4.0.0 | 6.84516E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99734E-07 | 0 | 0 |
| A/V | 7076 |
Ig-55 |
33 | rs374625641 |
0.1457 | 0.406 | 0.473 | N | 0.535 | 0.216 | None | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| A/V | 7076 |
Ig-55 |
33 | rs374625641 |
0.1457 | 0.406 | 0.473 | N | 0.535 | 0.216 | None | gnomAD-4.0.0 | 2.2583E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69876E-05 | 0 | 4.97183E-05 |
| N/I | 7169 |
Ig-56 |
33 | rs786205314 |
0.1035 | None | 0.003 | N | 0.487 | 0.145 | 0.414930877219 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/I | 7169 |
Ig-56 |
33 | rs786205314 |
0.1035 | None | 0.003 | N | 0.487 | 0.145 | 0.414930877219 | gnomAD-4.0.0 | 6.5741E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.4705E-05 | 0 | 0 |
| N/S | 7169 |
Ig-56 |
33 | rs786205314 |
0.0477 | -0.686 | None | N | 0.143 | 0.122 | None | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.55E-05 | None | 0 | 1.78E-05 | 0 |
| N/S | 7169 |
Ig-56 |
33 | rs786205314 |
0.0477 | -0.686 | None | N | 0.143 | 0.122 | None | gnomAD-4.0.0 | 1.30043E-05 | None | None | None | None | N | None | 2.98989E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 9.89606E-06 | 6.96056E-05 | 1.65777E-05 |
| N/T | 7169 |
Ig-56 |
33 | None | 0.0678 | -0.215 | None | N | 0.14 | 0.104 | 0.149567049428 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 1.29333E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| N/T | 7169 |
Ig-56 |
33 | None | 0.0678 | -0.215 | None | N | 0.14 | 0.104 | 0.149567049428 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| N/T | 7169 |
Ig-56 |
33 | None | 0.0678 | -0.215 | None | N | 0.14 | 0.104 | 0.149567049428 | gnomAD-4.0.0 | 8.05871E-06 | None | None | None | None | N | None | 5.34102E-05 | 0 | None | 0 | 1.785E-04 | None | 0 | 0 | 8.47775E-07 | 0 | 0 |
| T/A | 7262 |
Ig-57 |
33 | None | 0.0801 | None | 0.285 | N | 0.386 | 0.112 | 0.200317383148 | gnomAD-4.0.0 | 3.18385E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.86607E-05 | 0 |
| T/S | 7262 |
Ig-57 |
33 | rs200954184 |
0.0938 | -0.983 | 0.166 | N | 0.419 | 0.076 | 0.15556083564 | gnomAD-2.1.1 | 6.09E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.25739E-04 | 0 |
| T/S | 7262 |
Ig-57 |
33 | rs200954184 |
0.0938 | -0.983 | 0.166 | N | 0.419 | 0.076 | 0.15556083564 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.35E-05 | 0 | 0 |
| T/S | 7262 |
Ig-57 |
33 | rs200954184 |
0.0938 | -0.983 | 0.166 | N | 0.419 | 0.076 | 0.15556083564 | gnomAD-4.0.0 | 3.90515E-05 | None | None | None | None | N | None | 1.33579E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25606E-05 | 0 | 0 |
| S/P | 7355 |
Ig-58 |
33 | None | 0.9251 | None | 0.979 | D | 0.702 | 0.606 | 0.519187973786 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/S | 7547 |
Ig-60 |
33 | rs1437517914 |
0.0975 | -1.179 | 0.573 | N | 0.519 | 0.17 | 0.210429274316 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| T/S | 7547 |
Ig-60 |
33 | rs1437517914 |
0.0975 | -1.179 | 0.573 | N | 0.519 | 0.17 | 0.210429274316 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/S | 7547 |
Ig-60 |
33 | rs1437517914 |
0.0975 | -1.179 | 0.573 | N | 0.519 | 0.17 | 0.210429274316 | gnomAD-4.0.0 | 2.56298E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78829E-06 | 0 | 0 |
| S/L | 7641 |
Ig-61 |
34 | rs369508943 |
0.0611 | 0.579 | None | D | 0.299 | 0.152 | None | gnomAD-2.1.1 | 5.36E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.09582E-04 | 1.40687E-04 |
| S/L | 7641 |
Ig-61 |
34 | rs369508943 |
0.0611 | 0.579 | None | D | 0.299 | 0.152 | None | gnomAD-3.1.2 | 5.91E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.02911E-04 | 0 | 0 |
| S/L | 7641 |
Ig-61 |
34 | rs369508943 |
0.0611 | 0.579 | None | D | 0.299 | 0.152 | None | gnomAD-4.0.0 | 7.12877E-05 | None | None | None | None | N | None | 2.67073E-05 | 0 | None | 0 | 0 | None | 1.56245E-05 | 0 | 9.24216E-05 | 0 | 4.80554E-05 |
| V/G | 7734 |
Ig-62 |
33 | rs778239287 |
0.204 | -1.999 | 0.213 | N | 0.569 | 0.312 | 0.783236671049 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/G | 7734 |
Ig-62 |
33 | rs778239287 |
0.204 | -1.999 | 0.213 | N | 0.569 | 0.312 | 0.783236671049 | gnomAD-4.0.0 | 1.59215E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02663E-05 |
| V/I | 7734 |
Ig-62 |
33 | rs749838164 |
0.0748 | -0.43 | 0.002 | N | 0.192 | 0.093 | 0.52991035303 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| V/I | 7734 |
Ig-62 |
33 | rs749838164 |
0.0748 | -0.43 | 0.002 | N | 0.192 | 0.093 | 0.52991035303 | gnomAD-4.0.0 | 4.10626E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49814E-06 | 0 | 1.65728E-05 |
| V/L | 7734 |
Ig-62 |
33 | None | 0.1338 | None | 0.017 | N | 0.341 | 0.134 | 0.445210270852 | gnomAD-4.0.0 | 1.36875E-06 | None | None | None | None | N | None | 5.9805E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 7827 |
Ig-63 |
33 | rs758655083 |
0.1808 | -1.585 | 0.041 | N | 0.378 | 0.246 | 0.404733080969 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| V/F | 7827 |
Ig-63 |
33 | None | 0.1397 | None | 0.773 | D | 0.568 | 0.329 | 0.754833360098 | gnomAD-4.0.0 | 1.59146E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02462E-05 |
| S/N | 8203 |
Ig-67 |
33 | None | 0.0956 | None | None | N | 0.153 | 0.15 | 0.176091768786 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/R | 8203 |
Ig-67 |
33 | None | 0.2368 | None | 0.175 | N | 0.505 | 0.285 | 0.308278614506 | gnomAD-4.0.0 | 1.59154E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77423E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/P | 8296 |
Ig-68 |
33 | None | 0.9608 | None | 0.117 | D | 0.588 | 0.527 | 0.305086939656 | gnomAD-4.0.0 | 6.85202E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99535E-07 | 0 | 0 |
| S/T | 8296 |
Ig-68 |
33 | rs767731986 |
0.1114 | -0.34 | 0.001 | N | 0.248 | 0.091 | 0.149567049428 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 8.7E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/T | 8296 |
Ig-68 |
33 | rs767731986 |
0.1114 | -0.34 | 0.001 | N | 0.248 | 0.091 | 0.149567049428 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 8296 |
Ig-68 |
33 | rs767731986 |
0.1114 | -0.34 | 0.001 | N | 0.248 | 0.091 | 0.149567049428 | gnomAD-4.0.0 | 2.48203E-06 | None | None | None | None | N | None | 0 | 6.66756E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/S | 8582 |
Ig-71 |
34 | None | 0.1048 | None | 0.123 | N | 0.469 | 0.22 | 0.585261766934 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/V | 8582 |
Ig-71 |
34 | rs1420202972 |
0.06 | -1.593 | None | N | 0.219 | 0.094 | 0.245101548738 | gnomAD-2.1.1 | 7.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| L/V | 8582 |
Ig-71 |
34 | rs1420202972 |
0.06 | -1.593 | None | N | 0.219 | 0.094 | 0.245101548738 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| L/V | 8582 |
Ig-71 |
34 | rs1420202972 |
0.06 | -1.593 | None | N | 0.219 | 0.094 | 0.245101548738 | gnomAD-4.0.0 | 2.56512E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.79067E-06 | 0 | 0 |
| S/F | 8675 |
Ig-72 |
33 | rs868429008 |
0.1351 | -0.461 | 0.963 | D | 0.583 | 0.559 | 0.712839202888 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/F | 8675 |
Ig-72 |
33 | rs868429008 |
0.1351 | -0.461 | 0.963 | D | 0.583 | 0.559 | 0.712839202888 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 8675 |
Ig-72 |
33 | rs868429008 |
0.1351 | -0.461 | 0.963 | D | 0.583 | 0.559 | 0.712839202888 | gnomAD-4.0.0 | 2.56254E-06 | None | None | None | None | N | None | 3.38432E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 8958 |
Ig-75 |
33 | rs751670561 |
0.1563 | -0.413 | 0.188 | N | 0.597 | 0.277 | 0.619456947012 | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.25378E-04 | None | 0 | None | 0 | 0 | 0 |
| S/F | 8958 |
Ig-75 |
33 | rs751670561 |
0.1563 | -0.413 | 0.188 | N | 0.597 | 0.277 | 0.619456947012 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 8958 |
Ig-75 |
33 | rs751670561 |
0.1563 | -0.413 | 0.188 | N | 0.597 | 0.277 | 0.619456947012 | gnomAD-4.0.0 | 6.20299E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.33887E-04 | None | 0 | 0 | 3.39262E-06 | 0 | 0 |
| S/P | 8958 |
Ig-75 |
33 | rs886038913 |
0.8623 | None | 0.484 | N | 0.545 | 0.567 | 0.321393169273 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| S/P | 8958 |
Ig-75 |
33 | rs886038913 |
0.8623 | None | 0.484 | N | 0.545 | 0.567 | 0.321393169273 | gnomAD-4.0.0 | 6.57281E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47016E-05 | 0 | 0 |
| S/R | 9051 |
Ig-76 |
33 | rs1159097738 |
0.1715 | 0.048 | 0.473 | N | 0.516 | 0.338 | 0.3085936734 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| S/R | 9051 |
Ig-76 |
33 | rs1159097738 |
0.1715 | 0.048 | 0.473 | N | 0.516 | 0.338 | 0.3085936734 | gnomAD-4.0.0 | 1.36857E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99517E-07 | 1.15972E-05 | 0 |
| S/A | 9237 |
Ig-78 |
33 | rs766638714 |
0.0943 | -0.434 | 0.543 | D | 0.279 | 0.23 | 0.244539031024 | gnomAD-2.1.1 | 1.21408E-04 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.69023E-03 | None | 0 | None | 0 | 0 | 1.4041E-04 |
| S/A | 9237 |
Ig-78 |
33 | rs766638714 |
0.0943 | -0.434 | 0.543 | D | 0.279 | 0.23 | 0.244539031024 | gnomAD-3.1.2 | 5.92E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.73812E-03 | None | 0 | 0 | 0 | 0 | 0 |
| S/A | 9237 |
Ig-78 |
33 | rs766638714 |
0.0943 | -0.434 | 0.543 | D | 0.279 | 0.23 | 0.244539031024 | gnomAD-4.0.0 | 2.4788E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.24568E-04 | None | 0 | 0 | 0 | 0 | 4.80338E-05 |
| S/F | 9237 |
Ig-78 |
33 | rs1297278620 |
0.1231 | -0.469 | 0.999 | N | 0.733 | 0.625 | 0.825885774221 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/F | 9237 |
Ig-78 |
33 | rs1297278620 |
0.1231 | -0.469 | 0.999 | N | 0.733 | 0.625 | 0.825885774221 | gnomAD-4.0.0 | 2.05262E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99471E-07 | 2.31884E-05 | 0 |
| S/Y | 9237 |
Ig-78 |
33 | rs1297278620 |
0.1597 | -0.296 | 0.999 | N | 0.731 | 0.547 | 0.821864051555 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/Y | 9237 |
Ig-78 |
33 | rs1297278620 |
0.1597 | -0.296 | 0.999 | N | 0.731 | 0.547 | 0.821864051555 | gnomAD-4.0.0 | 2.05262E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99471E-07 | 1.15942E-05 | 1.65651E-05 |
| S/C | 9333 |
Ig-79 |
33 | None | 0.1622 | None | 0.965 | None | 0.643 | 0.608 | 0.729836406417 | gnomAD-4.0.0 | 1.59109E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43283E-05 | 0 |
| S/L | 9933 |
Ig-84 |
34 | rs764352461 |
0.5 | 0.601 | 1.0 | None | 0.715 | 0.494 | 0.673560067753 | gnomAD-2.1.1 | 1.09E-05 | None | None | None | None | N | None | 4.18E-05 | 0 | None | 0 | 0 | None | 3.3E-05 | None | 0 | 7.95E-06 | 0 |
| S/L | 9933 |
Ig-84 |
34 | rs764352461 |
0.5 | 0.601 | 1.0 | None | 0.715 | 0.494 | 0.673560067753 | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 1.44872E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 9933 |
Ig-84 |
34 | rs764352461 |
0.5 | 0.601 | 1.0 | None | 0.715 | 0.494 | 0.673560067753 | gnomAD-4.0.0 | 1.1789E-05 | None | None | None | None | N | None | 1.20179E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 7.63433E-06 | 1.10047E-05 | 0 |
| S/P | 9933 |
Ig-84 |
34 | rs1186600028 |
0.9884 | None | 1.0 | None | 0.786 | 0.594 | 0.494366844524 | gnomAD-4.0.0 | 1.59584E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86528E-06 | 0 | 0 |
| E/D | 10020 |
Ig-85 |
32 | rs764487564 |
0.2471 | -0.974 | 0.012 | None | 0.515 | 0.115 | 0.351830644314 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| E/D | 10020 |
Ig-85 |
32 | rs764487564 |
0.2471 | -0.974 | 0.012 | None | 0.515 | 0.115 | 0.351830644314 | gnomAD-4.0.0 | 6.84135E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15931E-05 | 0 |
| T/A | 10109 |
Ig-86 |
32 | rs2075197256 |
0.4795 | None | 0.911 | None | 0.581 | 0.334 | 0.342631996419 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| T/A | 13718 |
Ig-87 |
35 | rs562561380 |
0.0897 | -1.016 | 0.012 | D | 0.463 | 0.119 | 0.269111216191 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.06868E-04 | 0 |
| T/A | 13718 |
Ig-87 |
35 | rs562561380 |
0.0897 | -1.016 | 0.012 | D | 0.463 | 0.119 | 0.269111216191 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| T/A | 13718 |
Ig-87 |
35 | rs562561380 |
0.0897 | -1.016 | 0.012 | D | 0.463 | 0.119 | 0.269111216191 | gnomAD-4.0.0 | 6.57004E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| T/S | 13718 |
Ig-87 |
35 | rs562561380 |
0.0691 | None | None | N | 0.296 | 0.112 | 0.162503812791 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/I | 13811 |
Ig-88 |
32 | rs920253062 |
0.0954 | None | 0.543 | N | 0.293 | 0.118 | 0.246215685461 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| V/I | 13811 |
Ig-88 |
32 | rs920253062 |
0.0954 | None | 0.543 | N | 0.293 | 0.118 | 0.246215685461 | gnomAD-4.0.0 | 1.3153E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.94144E-05 | 0 | 0 |
| V/L | 13811 |
Ig-88 |
32 | None | 0.4529 | None | 0.948 | N | 0.509 | 0.12 | 0.384419519794 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| Q/R | 13996 |
Ig-90 |
32 | rs756260320 |
0.3998 | 0.029 | 0.03 | N | 0.525 | 0.15 | 0.101711395817 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| Q/R | 13996 |
Ig-90 |
32 | rs756260320 |
0.3998 | 0.029 | 0.03 | N | 0.525 | 0.15 | 0.101711395817 | gnomAD-4.0.0 | 1.50604E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.88945E-05 | 0 | 1.65744E-05 |
| I/M | 14084 |
Ig-91 |
31 | rs1163597313 |
0.1085 | -0.488 | 0.136 | N | 0.231 | 0.047 | 0.3349148499 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/M | 14084 |
Ig-91 |
31 | rs1163597313 |
0.1085 | -0.488 | 0.136 | N | 0.231 | 0.047 | 0.3349148499 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| I/M | 14084 |
Ig-91 |
31 | rs1163597313 |
0.1085 | -0.488 | 0.136 | N | 0.231 | 0.047 | 0.3349148499 | gnomAD-4.0.0 | 4.33899E-06 | None | None | None | None | N | None | 0 | 3.335E-05 | None | 0 | 0 | None | 0 | 0 | 1.69558E-06 | 2.19626E-05 | 1.60179E-05 |
| I/T | 14084 |
Ig-91 |
31 | rs757636133 |
0.3384 | -1.196 | 0.801 | N | 0.547 | 0.313 | 0.619433965396 | gnomAD-4.0.0 | 1.59216E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43308E-05 | 0 |
| I/V | 14084 |
Ig-91 |
31 | None | 0.1224 | None | 0.005 | N | 0.179 | 0.061 | 0.543254643676 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| V/A | 14173 |
Ig-92 |
32 | None | 0.1182 | None | 0.019 | N | 0.323 | 0.058 | 0.506068822696 | gnomAD-4.0.0 | 5.47485E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87273E-05 | 0 | 6.2975E-06 | 0 | 0 |
| K/R | 14261 |
Ig-93 |
31 | None | 0.0977 | None | 0.99 | N | 0.628 | 0.266 | 0.473774312618 | gnomAD-4.0.0 | 1.5923E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85959E-06 | 0 | 0 |
| R/C | 14439 |
Ig-95 |
32 | rs200914097 |
0.1814 | -1.253 | 1.0 | D | 0.68 | 0.447 | None | gnomAD-2.1.1 | 5.02E-05 | None | None | None | None | N | None | 3.72702E-04 | 2.83E-05 | None | 0 | 5.14E-05 | None | 0 | None | 0 | 2.36E-05 | 0 |
| R/C | 14439 |
Ig-95 |
32 | rs200914097 |
0.1814 | -1.253 | 1.0 | D | 0.68 | 0.447 | None | gnomAD-3.1.2 | 1.57936E-04 | None | None | None | None | N | None | 5.55797E-04 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 14439 |
Ig-95 |
32 | rs200914097 |
0.1814 | -1.253 | 1.0 | D | 0.68 | 0.447 | None | gnomAD-4.0.0 | 3.16147E-05 | None | None | None | None | N | None | 4.54351E-04 | 8.33973E-05 | None | 0 | 0 | None | 0 | 0 | 7.63011E-06 | 1.09808E-05 | 3.20379E-05 |
| R/H | 14439 |
Ig-95 |
32 | rs764117439 |
0.1101 | -1.64 | 0.159 | N | 0.325 | 0.247 | None | gnomAD-2.1.1 | 1.79E-05 | None | None | None | None | N | None | 0 | 5.66E-05 | None | 0 | 5.14E-05 | None | 0 | None | 0 | 1.58E-05 | 0 |
| R/H | 14439 |
Ig-95 |
32 | rs764117439 |
0.1101 | -1.64 | 0.159 | N | 0.325 | 0.247 | None | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 1.3113E-04 | 0 | 0 | 1.94099E-04 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/H | 14439 |
Ig-95 |
32 | rs764117439 |
0.1101 | -1.64 | 0.159 | N | 0.325 | 0.247 | None | gnomAD-4.0.0 | 1.05378E-05 | None | None | None | None | N | None | 1.33583E-05 | 5.00283E-05 | None | 0 | 2.23085E-05 | None | 0 | 0 | 6.78234E-06 | 3.29424E-05 | 1.60164E-05 |
| R/L | 14439 |
Ig-95 |
32 | rs764117439 |
0.3677 | -0.23 | 0.976 | D | 0.659 | 0.458 | 0.421427970867 | gnomAD-4.0.0 | 6.84359E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52054E-05 | None | 0 | 0 | 0 | 0 | 0 |
| N/S | 14706 |
Ig-98 |
32 | rs878854309 |
0.076 | -0.608 | 0.001 | N | 0.202 | 0.086 | 0.0551355673512 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14705E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/T | 15062 |
Ig-102 |
32 | rs373627060 |
0.087 | -1.723 | None | N | 0.178 | 0.23 | None | gnomAD-2.1.1 | 5.66E-05 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 3.92311E-04 | None | 0 | 0 | 1.66556E-04 |
| I/T | 15062 |
Ig-102 |
32 | rs373627060 |
0.087 | -1.723 | None | N | 0.178 | 0.23 | None | gnomAD-3.1.2 | 1.98E-05 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.1632E-04 | 0 |
| I/T | 15062 |
Ig-102 |
32 | rs373627060 |
0.087 | -1.723 | None | N | 0.178 | 0.23 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| I/T | 15062 |
Ig-102 |
32 | rs373627060 |
0.087 | -1.723 | None | N | 0.178 | 0.23 | None | gnomAD-4.0.0 | 2.29474E-05 | None | None | None | None | N | None | 2.67051E-05 | 0 | None | 0 | 2.23954E-05 | None | 0 | 0 | 1.69627E-06 | 3.40562E-04 | 1.60251E-05 |
| K/N | 15239 |
Ig-104 |
32 | None | 0.7336 | None | 1.0 | D | 0.757 | 0.446 | 0.345405024496 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/I | 15995 |
Ig-109 |
28 | rs1205858771 |
0.1516 | -0.007 | 0.035 | N | 0.592 | 0.186 | 0.514015564596 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.68161E-04 | None | 0 | None | 0 | 0 | 0 |
| T/I | 15995 |
Ig-109 |
28 | rs1205858771 |
0.1516 | -0.007 | 0.035 | N | 0.592 | 0.186 | 0.514015564596 | gnomAD-4.0.0 | 4.78025E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 8.34307E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 16987 |
Ig-111 |
33 | rs532794938 |
0.4221 | -0.648 | 0.627 | N | 0.586 | 0.175 | 0.257786959452 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 1.29316E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/R | 16987 |
Ig-111 |
33 | rs532794938 |
0.4221 | -0.648 | 0.627 | N | 0.586 | 0.175 | 0.257786959452 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 1.44809E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/R | 16987 |
Ig-111 |
33 | rs532794938 |
0.4221 | -0.648 | 0.627 | N | 0.586 | 0.175 | 0.257786959452 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| S/R | 16987 |
Ig-111 |
33 | rs532794938 |
0.4221 | -0.648 | 0.627 | N | 0.586 | 0.175 | 0.257786959452 | gnomAD-4.0.0 | 8.68048E-06 | None | None | None | None | N | None | 1.7337E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60195E-05 |
| T/K | 17280 |
Ig-112 |
30 | rs1225457381 |
0.2418 | -0.116 | 0.997 | D | 0.777 | 0.423 | 0.490489133298 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| T/K | 17280 |
Ig-112 |
30 | rs1225457381 |
0.2418 | -0.116 | 0.997 | D | 0.777 | 0.423 | 0.490489133298 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/K | 17280 |
Ig-112 |
30 | rs1225457381 |
0.2418 | -0.116 | 0.997 | D | 0.777 | 0.423 | 0.490489133298 | gnomAD-4.0.0 | 6.58432E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47223E-05 | 0 | 0 |
| V/I | 17705 |
Ig-113 |
29 | None | 0.0793 | None | 0.101 | N | 0.41 | 0.067 | 0.318252033908 | gnomAD-4.0.0 | 4.77693E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72138E-06 | 1.43303E-05 | 0 |
| T/I | 18717 |
Ig-116 |
30 | rs794729460 |
0.1443 | 0.605 | 0.885 | D | 0.603 | 0.338 | 0.442054744378 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| T/I | 18717 |
Ig-116 |
30 | rs794729460 |
0.1443 | 0.605 | 0.885 | D | 0.603 | 0.338 | 0.442054744378 | gnomAD-4.0.0 | 2.05405E-06 | None | None | None | None | N | None | 5.98587E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99878E-07 | 0 | 0 |
| T/I | 19819 |
Ig-119 |
30 | rs758287054 |
0.117 | 0.147 | 0.322 | N | 0.415 | 0.322 | 0.374434639691 | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 1.65399E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 19819 |
Ig-119 |
30 | rs758287054 |
0.117 | 0.147 | 0.322 | N | 0.415 | 0.322 | 0.374434639691 | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 1.44816E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 19819 |
Ig-119 |
30 | rs758287054 |
0.117 | 0.147 | 0.322 | N | 0.415 | 0.322 | 0.374434639691 | gnomAD-4.0.0 | 4.95871E-06 | None | None | None | None | N | None | 1.06846E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 19819 |
Ig-119 |
30 | rs758287054 |
0.1083 | -1.057 | 0.17 | N | 0.452 | 0.087 | 0.221019684889 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/S | 19819 |
Ig-119 |
30 | rs758287054 |
0.1083 | -1.057 | 0.17 | N | 0.452 | 0.087 | 0.221019684889 | gnomAD-4.0.0 | 6.84318E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99588E-07 | 0 | 0 |
| T/S | 20509 |
Ig-121 |
31 | None | 0.1013 | None | 0.669 | N | 0.57 | 0.093 | 0.180583059064 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| A/V | 20802 |
Ig-122 |
34 | rs1285688683 |
0.0668 | None | None | N | 0.249 | 0.085 | 0.124217242631 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/V | 20802 |
Ig-122 |
34 | rs1285688683 |
0.0668 | None | None | N | 0.249 | 0.085 | 0.124217242631 | gnomAD-4.0.0 | 6.57748E-06 | None | None | None | None | N | None | 0 | 6.55652E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 21207 |
Ig-123 |
31 | None | 0.627 | None | 1.0 | D | 0.727 | 0.604 | 0.498705051145 | gnomAD-4.0.0 | 1.59309E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86085E-06 | 0 | 0 |
| T/S | 22294 |
Ig-126 |
30 | rs2047448209 |
0.1377 | None | 0.17 | N | 0.258 | 0.109 | 0.148003135375 | gnomAD-4.0.0 | 2.05367E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99769E-07 | 2.31959E-05 | 0 |
| S/Y | 22583 |
Ig-127 |
24 | None | 0.1528 | None | 0.295 | D | 0.578 | 0.273 | 0.545739167163 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/G | 22980 |
Ig-128 |
31 | rs2046674740 |
0.1323 | None | None | N | 0.184 | 0.186 | 0.201204373187 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 6.58E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/G | 22980 |
Ig-128 |
31 | rs2046674740 |
0.1323 | None | None | N | 0.184 | 0.186 | 0.201204373187 | gnomAD-4.0.0 | 2.56537E-06 | None | None | None | None | N | None | 0 | 1.69722E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 2.84722E-05 |
| T/I | 23666 |
Ig-130 |
30 | rs548118690 |
0.0939 | 0.076 | 0.925 | D | 0.549 | 0.349 | 0.477529508747 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| T/I | 23666 |
Ig-130 |
30 | rs548118690 |
0.0939 | 0.076 | 0.925 | D | 0.549 | 0.349 | 0.477529508747 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07383E-04 | 0 |
| T/I | 23666 |
Ig-130 |
30 | rs548118690 |
0.0939 | 0.076 | 0.925 | D | 0.549 | 0.349 | 0.477529508747 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| T/I | 23666 |
Ig-130 |
30 | rs548118690 |
0.0939 | 0.076 | 0.925 | D | 0.549 | 0.349 | 0.477529508747 | gnomAD-4.0.0 | 2.56714E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39646E-06 | 1.34452E-05 | 0 |
| T/S | 23666 |
Ig-130 |
30 | None | 0.0886 | None | 0.287 | N | 0.233 | 0.125 | 0.141422826196 | gnomAD-4.0.0 | 1.59348E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86128E-06 | 0 | 0 |
| E/G | 24062 |
Ig-131 |
34 | rs893332061 |
0.143 | None | 0.27 | N | 0.459 | 0.305 | 0.402471007487 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/G | 24062 |
Ig-131 |
34 | rs893332061 |
0.143 | None | 0.27 | N | 0.459 | 0.305 | 0.402471007487 | gnomAD-4.0.0 | 2.56352E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78819E-06 | 0 | 0 |
| K/E | 24461 |
Ig-132 |
31 | rs916071227 |
0.2558 | 0.426 | 0.892 | D | 0.556 | 0.297 | 0.33110744837 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| K/E | 24461 |
Ig-132 |
31 | rs916071227 |
0.2558 | 0.426 | 0.892 | D | 0.556 | 0.297 | 0.33110744837 | gnomAD-4.0.0 | 1.02648E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.34938E-05 | 0 | 0 |
| K/R | 24461 |
Ig-132 |
31 | None | 0.082 | None | 0.056 | N | 0.483 | 0.088 | 0.284150004643 | gnomAD-4.0.0 | 1.59185E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.77624E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 24748 |
Ig-133 |
33 | rs768606900 |
0.0811 | 0.226 | 0.193 | D | 0.569 | 0.153 | 0.227260227426 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/I | 24748 |
Ig-133 |
33 | rs768606900 |
0.0811 | 0.226 | 0.193 | D | 0.569 | 0.153 | 0.227260227426 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 24748 |
Ig-133 |
33 | rs768606900 |
0.0811 | 0.226 | 0.193 | D | 0.569 | 0.153 | 0.227260227426 | gnomAD-4.0.0 | 5.57875E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.62978E-06 | 0 | 0 |
| Q/L | 25144 |
Ig-134 |
34 | rs1168512437 |
0.0999 | 0.634 | 0.213 | N | 0.493 | 0.231 | 0.373537453441 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| Q/L | 25144 |
Ig-134 |
34 | rs1168512437 |
0.0999 | 0.634 | 0.213 | N | 0.493 | 0.231 | 0.373537453441 | gnomAD-4.0.0 | 1.59167E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| K/E | 25543 |
Ig-135 |
30 | rs372016541 |
0.2553 | 0.108 | 0.892 | N | 0.479 | 0.34 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| K/E | 25543 |
Ig-135 |
30 | rs372016541 |
0.2553 | 0.108 | 0.892 | N | 0.479 | 0.34 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/E | 25543 |
Ig-135 |
30 | rs372016541 |
0.2553 | 0.108 | 0.892 | N | 0.479 | 0.34 | None | gnomAD-4.0.0 | 4.34098E-06 | None | None | None | None | N | None | 2.67158E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.24057E-06 | 0 | 0 |
| K/R | 25543 |
Ig-135 |
30 | None | 0.0858 | None | 0.892 | N | 0.495 | 0.238 | 0.425028116352 | gnomAD-4.0.0 | 1.20033E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31251E-06 | 0 | 0 |
| T/N | 25830 |
Ig-136 |
33 | rs1475904379 |
0.1104 | -0.491 | 0.331 | N | 0.548 | 0.245 | 0.372446077551 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/N | 25830 |
Ig-136 |
33 | rs1475904379 |
0.1104 | -0.491 | 0.331 | N | 0.548 | 0.245 | 0.372446077551 | gnomAD-4.0.0 | 1.59205E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43332E-05 | 0 |
| T/S | 25830 |
Ig-136 |
33 | rs1475904379 |
0.088 | -0.779 | 0.001 | N | 0.351 | 0.051 | 0.134241683229 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.665E-04 |
| E/D | 26226 |
Ig-137 |
34 | rs1251054791 |
0.2386 | -1.164 | 0.285 | N | 0.404 | 0.06 | 0.211220785272 | gnomAD-2.1.1 | 8.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.56E-05 | None | 0 | 0 | 0 |
| E/D | 26226 |
Ig-137 |
34 | rs1251054791 |
0.2386 | -1.164 | 0.285 | N | 0.404 | 0.06 | 0.211220785272 | gnomAD-4.0.0 | 2.05362E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.48489E-05 | 0 |
| E/K | 26226 |
Ig-137 |
34 | rs754878387 |
0.1154 | -0.557 | 0.001 | N | 0.152 | 0.255 | 0.266385636622 | gnomAD-2.1.1 | 5.01E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 4.41023E-04 | 1.56E-05 | 1.40924E-04 |
| E/K | 26226 |
Ig-137 |
34 | rs754878387 |
0.1154 | -0.557 | 0.001 | N | 0.152 | 0.255 | 0.266385636622 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.42E-05 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 26226 |
Ig-137 |
34 | rs754878387 |
0.1154 | -0.557 | 0.001 | N | 0.152 | 0.255 | 0.266385636622 | gnomAD-4.0.0 | 1.98402E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.06415E-04 | 0 | 2.54365E-06 | 0 | 4.80554E-05 |
| E/Q | 26226 |
Ig-137 |
34 | rs754878387 |
0.0831 | -0.791 | 0.002 | N | 0.11 | 0.096 | None | gnomAD-2.1.1 | 6.8E-05 | None | None | None | None | N | None | 0 | 2.83672E-04 | None | 2.9098E-04 | 0 | None | 0 | None | 0 | 3.91E-05 | 1.40924E-04 |
| E/Q | 26226 |
Ig-137 |
34 | rs754878387 |
0.0831 | -0.791 | 0.002 | N | 0.11 | 0.096 | None | gnomAD-3.1.2 | 5.26E-05 | None | None | None | None | N | None | 0 | 1.96567E-04 | 0 | 8.65052E-04 | 0 | None | 0 | 3.16456E-03 | 1.47E-05 | 0 | 0 |
| E/Q | 26226 |
Ig-137 |
34 | rs754878387 |
0.0831 | -0.791 | 0.002 | N | 0.11 | 0.096 | None | gnomAD-4.0.0 | 4.15375E-05 | None | None | None | None | N | None | 0 | 2.66845E-04 | None | 3.72024E-04 | 0 | None | 0 | 4.96032E-04 | 2.54367E-05 | 0 | 1.1209E-04 |
| T/I | 26625 |
Ig-138 |
32 | rs1705799804 |
0.0982 | None | 0.002 | N | 0.351 | 0.147 | 0.311079019809 | gnomAD-4.0.0 | 3.18295E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77393E-05 | None | 0 | 0 | 0 | 1.43275E-05 | 0 |
| S/Y | 26912 |
Ig-139 |
33 | rs1198056349 |
0.1423 | -0.581 | 0.873 | N | 0.553 | 0.449 | 0.450152462452 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| S/Y | 26912 |
Ig-139 |
33 | rs1198056349 |
0.1423 | -0.581 | 0.873 | N | 0.553 | 0.449 | 0.450152462452 | gnomAD-4.0.0 | 1.59171E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77454E-05 | None | 0 | 0 | 0 | 0 | 0 |
| V/F | 27308 |
Ig-140 |
31 | rs1704782856 |
0.0856 | None | 0.188 | N | 0.615 | 0.154 | 0.582232187747 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/F | 27308 |
Ig-140 |
31 | rs1704782856 |
0.0856 | None | 0.188 | N | 0.615 | 0.154 | 0.582232187747 | gnomAD-4.0.0 | 4.95833E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93331E-06 | 0 | 1.60123E-05 |
| V/L | 27308 |
Ig-140 |
31 | rs1704782856 |
0.0881 | None | None | N | 0.247 | 0.064 | 0.227934060464 | gnomAD-4.0.0 | 6.84317E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15934E-05 | 0 |
| K/Q | 27708 |
Ig-141 |
33 | None | 0.1664 | None | 0.942 | N | 0.551 | 0.338 | 0.342400092842 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/T | 27708 |
Ig-141 |
33 | None | 0.1766 | None | 0.032 | N | 0.404 | 0.239 | 0.19670166235 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| N/T | 27995 |
Ig-142 |
33 | rs751728774 |
0.0486 | -0.027 | None | N | 0.115 | 0.084 | 0.0482279557977 | gnomAD-2.1.1 | 8.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| N/T | 27995 |
Ig-142 |
33 | rs751728774 |
0.0486 | -0.027 | None | N | 0.115 | 0.084 | 0.0482279557977 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/T | 27995 |
Ig-142 |
33 | rs751728774 |
0.0486 | -0.027 | None | N | 0.115 | 0.084 | 0.0482279557977 | gnomAD-4.0.0 | 4.95929E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.78203E-06 | 0 | 0 |
| S/F | 28390 |
Ig-143 |
33 | rs267599032 |
0.1653 | None | 0.994 | N | 0.712 | 0.574 | 0.660933345464 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| L/S | 28787 |
Ig-144 |
33 | rs1237283720 |
0.0786 | -1.053 | None | N | 0.256 | 0.105 | 0.181679512989 | gnomAD-2.1.1 | 4.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.13E-06 | 0 |
| L/S | 28787 |
Ig-144 |
33 | rs1237283720 |
0.0786 | -1.053 | None | N | 0.256 | 0.105 | 0.181679512989 | gnomAD-4.0.0 | 1.61777E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89942E-06 | 0 | 0 |
| T/A | 29077 |
Ig-145 |
33 | None | 0.0869 | None | 0.704 | N | 0.495 | 0.203 | 0.271763555656 | gnomAD-4.0.0 | 1.59114E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85788E-06 | 0 | 0 |
| T/I | 29077 |
Ig-145 |
33 | rs763627957 |
0.1069 | 0.018 | 0.988 | N | 0.555 | 0.372 | 0.447311733946 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.67E-05 | 0 |
| T/I | 29077 |
Ig-145 |
33 | rs763627957 |
0.1069 | 0.018 | 0.988 | N | 0.555 | 0.372 | 0.447311733946 | gnomAD-4.0.0 | 4.78932E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39661E-06 | 0 | 1.65645E-05 |
| E/D | 29473 |
Ig-146 |
30 | rs1575552905 |
0.3189 | None | 0.999 | D | 0.511 | 0.229 | 0.266843984389 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 29473 |
Ig-146 |
30 | rs1575552905 |
0.3189 | None | 0.999 | D | 0.511 | 0.229 | 0.266843984389 | gnomAD-4.0.0 | 2.56232E-06 | None | None | None | None | N | None | 0 | 1.69492E-05 | None | 0 | 0 | None | 0 | 0 | 2.39275E-06 | 0 | 0 |
| T/K | 29872 |
Ig-147 |
31 | None | 0.2655 | None | 0.497 | N | 0.611 | 0.231 | 0.280987212366 | gnomAD-4.0.0 | 6.8614E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99467E-07 | 0 | 0 |
| T/I | 30559 |
Ig-149 |
28 | rs1204855591 |
0.0927 | 0.509 | 0.811 | N | 0.579 | 0.294 | 0.430808444494 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| T/I | 30559 |
Ig-149 |
28 | rs1204855591 |
0.0927 | 0.509 | 0.811 | N | 0.579 | 0.294 | 0.430808444494 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/I | 30559 |
Ig-149 |
28 | rs1204855591 |
0.0927 | 0.509 | 0.811 | N | 0.579 | 0.294 | 0.430808444494 | gnomAD-4.0.0 | 6.57756E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47054E-05 | 0 | 0 |
| T/P | 30559 |
Ig-149 |
28 | rs774619016 |
0.7183 | -0.147 | 0.995 | D | 0.672 | 0.557 | 0.557012442849 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| T/P | 30559 |
Ig-149 |
28 | rs774619016 |
0.7183 | -0.147 | 0.995 | D | 0.672 | 0.557 | 0.557012442849 | gnomAD-4.0.0 | 1.59128E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85845E-06 | 0 | 0 |
| I/F | 31648 |
Ig-152 |
28 | rs1409620740 |
0.097 | -0.915 | None | N | 0.157 | 0.215 | 0.464528537357 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| I/F | 31648 |
Ig-152 |
28 | rs1409620740 |
0.097 | -0.915 | None | N | 0.157 | 0.215 | 0.464528537357 | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77316E-05 | None | 0 | 0 | 0 | 0 | 0 |
| I/V | 31648 |
Ig-152 |
28 | None | 0.077 | None | 0.047 | N | 0.27 | 0.138 | 0.496299407791 | gnomAD-4.0.0 | 1.59127E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85838E-06 | 0 | 0 |
| T/M | 32047 |
Ig-153 |
31 | rs375640847 |
0.0998 | 0.029 | 1.0 | N | 0.642 | 0.499 | None | gnomAD-2.1.1 | 3.93E-05 | None | None | None | None | N | None | 4.13E-05 | 0 | None | 0 | 5.12E-05 | None | 9.8E-05 | None | 0 | 4.68E-05 | 0 |
| T/M | 32047 |
Ig-153 |
31 | rs375640847 |
0.0998 | 0.029 | 1.0 | N | 0.642 | 0.499 | None | gnomAD-3.1.2 | 3.95E-05 | None | None | None | None | N | None | 2.42E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 2.07469E-04 | 0 |
| T/M | 32047 |
Ig-153 |
31 | rs375640847 |
0.0998 | 0.029 | 1.0 | N | 0.642 | 0.499 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 0 | None | None | None | 1E-03 | None |
| T/M | 32047 |
Ig-153 |
31 | rs375640847 |
0.0998 | 0.029 | 1.0 | N | 0.642 | 0.499 | None | gnomAD-4.0.0 | 3.40851E-05 | None | None | None | None | N | None | 2.66752E-05 | 1.667E-05 | None | 0 | 0 | None | 0 | 0 | 3.47544E-05 | 8.78445E-05 | 4.80231E-05 |
| T/R | 32047 |
Ig-153 |
31 | None | 0.1098 | None | 0.999 | D | 0.657 | 0.454 | 0.563099480232 | gnomAD-4.0.0 | 6.84258E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.15937E-05 | 0 |
| S/P | 32339 |
Ig-154 |
33 | None | 0.9131 | None | 0.999 | N | 0.744 | 0.671 | 0.47290127212 | gnomAD-4.0.0 | 2.73676E-06 | None | None | None | None | N | None | 0 | 2.23614E-05 | None | 0 | 0 | None | 0 | 0 | 2.69836E-06 | 0 | 0 |
| K/T | 33133 |
Ig-156 |
33 | rs794729552 |
0.3007 | None | 0.998 | N | 0.665 | 0.527 | 0.36893422563 | gnomAD-4.0.0 | 1.59145E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85851E-06 | 0 | 0 |
| T/I | 33628 |
Ig-159 |
33 | rs200085900 |
0.7918 | None | 1.0 | N | 0.761 | 0.567 | 0.7073580974 | gnomAD-4.0.0 | 3.18286E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.4108E-04 | 2.85847E-06 | 0 | 0 |
| T/I | 34169 |
Ig-160 |
33 | rs1410488429 |
0.3593 | 0.401 | 0.994 | N | 0.569 | 0.495 | 0.614800550379 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| T/I | 34169 |
Ig-160 |
33 | rs1410488429 |
0.3593 | 0.401 | 0.994 | N | 0.569 | 0.495 | 0.614800550379 | gnomAD-4.0.0 | 4.77291E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.7154E-06 | 0 | 3.02352E-05 |
| T/P | 34290 |
Ig-161 |
33 | None | 0.8335 | None | 0.99 | D | 0.673 | 0.634 | 0.55350970329 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 3.66327E-05 |
| T/R | 34290 |
Ig-161 |
33 | None | 0.2563 | None | 0.942 | D | 0.673 | 0.387 | 0.490419987736 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/Q | 34395 |
Ig-162 |
33 | rs368320079 |
0.156 | 0.021 | 0.968 | N | 0.646 | 0.238 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| K/Q | 34395 |
Ig-162 |
33 | rs368320079 |
0.156 | 0.021 | 0.968 | N | 0.646 | 0.238 | None | gnomAD-4.0.0 | 3.18218E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.7154E-06 | 0 | 0 |
| T/A | 35161 |
Ig-164 |
33 | rs764804165 |
0.1172 | -0.568 | 0.552 | N | 0.549 | 0.202 | 0.241664281697 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/A | 35161 |
Ig-164 |
33 | rs764804165 |
0.1172 | -0.568 | 0.552 | N | 0.549 | 0.202 | 0.241664281697 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.21507E-04 | 0 |
| T/N | 35161 |
Ig-164 |
33 | rs372263729 |
0.1596 | -0.418 | 0.954 | N | 0.555 | 0.33 | None | gnomAD-2.1.1 | 4.63E-05 | None | None | None | None | N | None | 5.37501E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/N | 35161 |
Ig-164 |
33 | rs372263729 |
0.1596 | -0.418 | 0.954 | N | 0.555 | 0.33 | None | gnomAD-3.1.2 | 1.70913E-04 | None | None | None | None | N | None | 6.27655E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 35161 |
Ig-164 |
33 | rs372263729 |
0.1596 | -0.418 | 0.954 | N | 0.555 | 0.33 | None | gnomAD-4.0.0 | 3.22217E-05 | None | None | None | None | N | None | 6.40837E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 8.47542E-07 | 0 | 4.80246E-05 |
| T/S | 35161 |
Ig-164 |
33 | rs764804165 |
0.1442 | None | 0.189 | N | 0.483 | 0.129 | 0.151104730317 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/S | 35161 |
Ig-164 |
33 | rs764804165 |
0.1442 | None | 0.189 | N | 0.483 | 0.129 | 0.151104730317 | gnomAD-4.0.0 | 6.84137E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.65634E-05 |
| T/N | 35318 |
Ig-165 |
33 | rs1391706140 |
0.1374 | None | 0.029 | N | 0.459 | 0.095 | 0.229924730088 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 35318 |
Ig-165 |
33 | rs1391706140 |
0.1374 | None | 0.029 | N | 0.459 | 0.095 | 0.229924730088 | gnomAD-4.0.0 | 6.57505E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47011E-05 | 0 | 0 |
| T/S | 35318 |
Ig-165 |
33 | rs1688710616 |
0.1142 | None | None | N | 0.183 | 0.162 | 0.143124449307 | gnomAD-4.0.0 | 3.18173E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.715E-06 | 0 | 0 |
| I/M | 35452 |
Ig-166 |
33 | None | 0.1009 | None | 0.074 | N | 0.526 | 0.03 | 0.292062946507 | gnomAD-4.0.0 | 1.61619E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.46675E-05 | 0 |
| K/N | 35637 |
Ig-167 |
31 | rs767045071 |
0.695 | None | 0.782 | N | 0.563 | 0.202 | 0.154104182512 | gnomAD-4.0.0 | 1.91561E-05 | None | None | None | None | N | None | 5.97372E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.33843E-05 | 0 | 0 |
| E/K | 35734 |
Ig-168 |
33 | rs374992991 |
0.4493 | -0.513 | 0.996 | N | 0.514 | 0.336 | None | gnomAD-2.1.1 | 8.16E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| E/K | 35734 |
Ig-168 |
33 | rs374992991 |
0.4493 | -0.513 | 0.996 | N | 0.514 | 0.336 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 35734 |
Ig-168 |
33 | rs374992991 |
0.4493 | -0.513 | 0.996 | N | 0.514 | 0.336 | None | gnomAD-4.0.0 | 1.11887E-05 | None | None | None | None | N | None | 1.33858E-05 | 0 | None | 0 | 2.23294E-05 | None | 0 | 0 | 7.64783E-06 | 6.63394E-05 | 1.60637E-05 |
| T/K | 35929 |
Ig-169 |
33 | rs751035844 |
0.1965 | -0.576 | 0.042 | N | 0.537 | 0.265 | 0.378322506985 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | -1.679(OBSL1) -0.527(OBSCN) | N | None | 0 | 0 | 0 | 0 | 0 | None | 1.8843E-04 | 0 | 0 | 0 | 0 |
| T/K | 35929 |
Ig-169 |
33 | rs751035844 |
0.1965 | -0.576 | 0.042 | N | 0.537 | 0.265 | 0.378322506985 | gnomAD-4.0.0 | 3.71452E-05 | None | None | None | -1.679(OBSL1) -0.527(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 4.0792E-04 | 0 | 2.39252E-06 | 0 | 5.68796E-05 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.