Structural position:
- Domain Type: Ig
- Aligned Position: 5
- Secondary Structure Element: e
- Secondary Structure Region: β-strand A
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q/H | 10 |
Ig-1 |
5 | None | 0.3457 | None | 0.754 | D | 0.349 | 0.403 | 0.508163421412 | gnomAD-4.0.0 | 1.59093E-06 | None | None | None | -0.628(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85721E-06 | 0 | 0 |
| Q/R | 10 |
Ig-1 |
5 | None | 0.1412 | None | 0.124 | N | 0.285 | 0.294 | 0.198526703765 | gnomAD-4.0.0 | 1.59096E-06 | None | None | None | -1.612(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85726E-06 | 0 | 0 |
| Q/E | 108 |
Ig-2 |
5 | None | 0.1132 | None | 0.987 | N | 0.354 | 0.44 | 0.344483371355 | gnomAD-4.0.0 | 1.60107E-06 | None | None | None | -0.238(TCAP) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87439E-06 | 0 | 0 |
| Q/K | 108 |
Ig-2 |
5 | rs1428387902 |
0.2592 | None | 0.994 | N | 0.423 | 0.473 | 0.290590437066 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | -0.902(TCAP) | N | None | 0 | 0 | 0 | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Q/K | 108 |
Ig-2 |
5 | rs1428387902 |
0.2592 | None | 0.994 | N | 0.423 | 0.473 | 0.290590437066 | gnomAD-4.0.0 | 6.5716E-06 | None | None | None | -0.902(TCAP) | N | None | 0 | 0 | None | 0 | 1.92901E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 108 |
Ig-2 |
5 | None | 0.2929 | None | 0.991 | N | 0.471 | 0.533 | 0.272205846399 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | -0.634(TCAP) | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 947 |
Ig-3 |
5 | rs761200839 |
0.1605 | 0.233 | 0.919 | N | 0.386 | 0.368 | None | gnomAD-2.1.1 | 4.38E-05 | None | None | None | None | N | None | 1.23031E-04 | 8.67E-05 | None | 0 | 1.08921E-04 | None | 3.27E-05 | None | 0 | 8.8E-06 | 3.26371E-04 |
| S/L | 947 |
Ig-3 |
5 | rs761200839 |
0.1605 | 0.233 | 0.919 | N | 0.386 | 0.368 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 2.42E-05 | 2.62605E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/L | 947 |
Ig-3 |
5 | rs761200839 |
0.1605 | 0.233 | 0.919 | N | 0.386 | 0.368 | None | gnomAD-4.0.0 | 1.98408E-05 | None | None | None | None | N | None | 4.01241E-05 | 1.0008E-04 | None | 0 | 8.92618E-05 | None | 0 | 0 | 1.0175E-05 | 3.29562E-05 | 6.40779E-05 |
| S/P | 947 |
Ig-3 |
5 | None | 0.8631 | None | 0.966 | N | 0.373 | 0.546 | 0.344945010812 | gnomAD-4.0.0 | 1.59137E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85819E-06 | 0 | 0 |
| T/A | 1086 |
Ig-4 |
5 | rs1167240676 |
0.0972 | -0.786 | 0.005 | N | 0.189 | 0.063 | 0.185906805712 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.81E-06 | 0 |
| T/A | 1086 |
Ig-4 |
5 | rs1167240676 |
0.0972 | -0.786 | 0.005 | N | 0.189 | 0.063 | 0.185906805712 | gnomAD-4.0.0 | 1.59056E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85657E-06 | 0 | 0 |
| T/R | 1086 |
Ig-4 |
5 | None | 0.1298 | None | None | N | 0.103 | 0.096 | 0.439339381091 | gnomAD-4.0.0 | 1.59054E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 1.88196E-05 | 0 | 0 | 0 | 0 |
| S/L | 1295 |
Ig-5 |
5 | rs1552280 |
0.0329 | 0.202 | None | N | 0.157 | 0.182 | None | gnomAD-2.1.1 | 9.60146E-01 | None | None | None | None | I | None | 8.67871E-01 | 9.39765E-01 | None | 9.92169E-01 | 8.80483E-01 | None | 9.57565E-01 | None | 9.78089E-01 | 9.89934E-01 | 9.70711E-01 |
| S/L | 1295 |
Ig-5 |
5 | rs1552280 |
0.0329 | 0.202 | None | N | 0.157 | 0.182 | None | gnomAD-3.1.2 | 9.47703E-01 | None | None | None | None | I | None | 8.68937E-01 | 9.63878E-01 | 8.43202E-01 | 9.93948E-01 | 8.72353E-01 | None | 9.80222E-01 | 9.77848E-01 | 9.91315E-01 | 9.51346E-01 | 9.47897E-01 |
| S/L | 1295 |
Ig-5 |
5 | rs1552280 |
0.0329 | 0.202 | None | N | 0.157 | 0.182 | None | 1000 genomes | 9.20128E-01 | None | None | None | None | I | None | 8.495E-01 | 9.496E-01 | None | None | 8.829E-01 | 9.92E-01 | None | None | None | 9.591E-01 | None |
| S/L | 1295 |
Ig-5 |
5 | rs1552280 |
0.0329 | 0.202 | None | N | 0.157 | 0.182 | None | gnomAD-4.0.0 | 9.77851E-01 | None | None | None | None | I | None | 8.67148E-01 | 9.48334E-01 | None | 9.92903E-01 | 8.7004E-01 | None | 9.77766E-01 | 9.84488E-01 | 9.92126E-01 | 9.58061E-01 | 9.69941E-01 |
| K/E | 1707 |
Ig-8 |
5 | None | 0.9271 | None | 0.999 | N | 0.567 | 0.399 | 0.457650129517 | gnomAD-4.0.0 | 6.84092E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9929E-07 | 0 | 0 |
| K/R | 1707 |
Ig-8 |
5 | None | 0.2141 | None | 0.999 | N | 0.52 | 0.286 | 0.337868961071 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 2082 |
Ig-10 |
5 | None | 0.9168 | -0.05 | 1.0 | N | 0.551 | 0.426 | 0.498259528926 | gnomAD-2.1.1 | 7.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.53E-05 | None | 0 | 0 | 0 |
| E/K | 2082 |
Ig-10 |
5 | None | 0.9168 | -0.05 | 1.0 | N | 0.551 | 0.426 | 0.498259528926 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 0 |
| E/K | 2082 |
Ig-10 |
5 | None | 0.9168 | -0.05 | 1.0 | N | 0.551 | 0.426 | 0.498259528926 | gnomAD-4.0.0 | 1.79681E-05 | None | None | None | None | N | None | 1.33486E-05 | 3.33444E-05 | None | 0 | 0 | None | 0 | 1.6442E-04 | 1.77965E-05 | 3.29337E-05 | 1.60041E-05 |
| E/Q | 2082 |
Ig-10 |
5 | rs750064248 |
0.6216 | None | 1.0 | N | 0.579 | 0.328 | 0.32471235697 | gnomAD-4.0.0 | 6.84091E-07 | None | None | None | None | N | None | 0 | 2.23684E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 2178 |
Ig-11 |
5 | None | 0.1268 | None | 0.77 | N | 0.536 | 0.4 | 0.253205268125 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 6.33473E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 2271 |
Ig-12 |
5 | None | 0.1088 | None | 0.999 | N | 0.544 | 0.354 | 0.409124616982 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/R | 2360 |
Ig-13 |
5 | rs796903749 |
0.2005 | 0.367 | 0.997 | N | 0.46 | 0.48 | 0.357724736475 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.45E-05 | None | 0 | None | 0 | 0 | 0 |
| Q/R | 2360 |
Ig-13 |
5 | rs796903749 |
0.2005 | 0.367 | 0.997 | N | 0.46 | 0.48 | 0.357724736475 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.8506E-04 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 2360 |
Ig-13 |
5 | rs796903749 |
0.2005 | 0.367 | 0.997 | N | 0.46 | 0.48 | 0.357724736475 | gnomAD-4.0.0 | 3.8421E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.27202E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/S | 2537 |
Ig-15 |
5 | None | 0.494 | None | 0.379 | N | 0.452 | 0.359 | 0.28722502521 | gnomAD-4.0.0 | 6.84136E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99319E-07 | 0 | 0 |
| K/Q | 2624 |
Ig-16 |
4 | None | 0.1412 | None | 0.002 | N | 0.133 | 0.128 | 0.119812018005 | gnomAD-4.0.0 | 1.59111E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43287E-05 | 0 |
| K/R | 2624 |
Ig-16 |
4 | rs1163440648 |
0.0895 | None | None | N | 0.138 | 0.124 | 0.207176502487 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 2624 |
Ig-16 |
4 | rs1163440648 |
0.0895 | None | None | N | 0.138 | 0.124 | 0.207176502487 | gnomAD-4.0.0 | 5.07456E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.02458E-06 | 0 | 0 |
| K/E | 2711 |
Ig-17 |
5 | None | 0.2966 | None | 0.999 | D | 0.609 | 0.541 | 0.617224619168 | gnomAD-4.0.0 | 2.40065E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.62501E-06 | 0 | 0 |
| K/I | 2799 |
Ig-18 |
5 | None | 0.9636 | None | 0.013 | D | 0.445 | 0.352 | 0.61907107664 | gnomAD-4.0.0 | 6.84062E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99287E-07 | 0 | 0 |
| K/Q | 2799 |
Ig-18 |
5 | None | 0.5489 | None | 0.975 | N | 0.697 | 0.317 | 0.361558571881 | gnomAD-4.0.0 | 1.59047E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77331E-05 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 2799 |
Ig-18 |
5 | None | 0.12 | None | 0.787 | N | 0.583 | 0.244 | 0.401042353794 | gnomAD-4.0.0 | 6.84062E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99287E-07 | 0 | 0 |
| S/F | 2973 |
Ig-20 |
5 | rs1422918590 |
0.6347 | -0.926 | 1.0 | D | 0.803 | 0.524 | 0.816535969511 | gnomAD-2.1.1 | 3.99E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| S/F | 2973 |
Ig-20 |
5 | rs1422918590 |
0.6347 | -0.926 | 1.0 | D | 0.803 | 0.524 | 0.816535969511 | gnomAD-4.0.0 | 6.36505E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.88758E-05 | 0 | 5.71331E-06 | 1.43299E-05 | 0 |
| K/R | 3062 |
Ig-21 |
5 | rs769821924 |
0.1502 | -0.185 | 0.64 | N | 0.261 | 0.168 | 0.3085936734 | gnomAD-2.1.1 | 1.99E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 4.42E-05 | 0 |
| K/R | 3062 |
Ig-21 |
5 | rs769821924 |
0.1502 | -0.185 | 0.64 | N | 0.261 | 0.168 | 0.3085936734 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/R | 3062 |
Ig-21 |
5 | rs769821924 |
0.1502 | -0.185 | 0.64 | N | 0.261 | 0.168 | 0.3085936734 | gnomAD-4.0.0 | 2.85012E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.81353E-05 | 0 | 1.60046E-05 |
| S/N | 3151 |
Ig-22 |
5 | rs749077031 |
0.3813 | -0.191 | 0.961 | N | 0.39 | 0.233 | 0.318540980066 | gnomAD-2.1.1 | 7.97E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.44E-05 | None | 0 | None | 0 | 8.82E-06 | 0 |
| S/N | 3151 |
Ig-22 |
5 | rs749077031 |
0.3813 | -0.191 | 0.961 | N | 0.39 | 0.233 | 0.318540980066 | gnomAD-4.0.0 | 2.05225E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51902E-05 | None | 0 | 0 | 1.79861E-06 | 0 | 0 |
| S/R | 3151 |
Ig-22 |
5 | rs879041803 |
0.9341 | None | 0.989 | N | 0.429 | 0.326 | 0.230578612272 | gnomAD-4.0.0 | 1.59056E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85659E-06 | 0 | 0 |
| Q/E | 3243 |
Ig-23 |
5 | None | 0.0894 | None | 0.27 | N | 0.21 | 0.264 | 0.258283824007 | gnomAD-4.0.0 | 6.8438E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99394E-07 | 0 | 0 |
| Q/R | 3243 |
Ig-23 |
5 | None | 0.0852 | None | 0.001 | N | 0.117 | 0.268 | 0.183819452728 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/A | 3349 |
Ig-24 |
5 | rs777960129 |
0.0873 | -0.815 | None | N | 0.101 | 0.064 | 0.180583059064 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.8E-06 | 0 |
| T/A | 3349 |
Ig-24 |
5 | rs777960129 |
0.0873 | -0.815 | None | N | 0.101 | 0.064 | 0.180583059064 | gnomAD-4.0.0 | 7.52495E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99313E-06 | 0 | 1.65579E-05 |
| T/I | 3349 |
Ig-24 |
5 | rs727503678 |
0.1203 | 0.098 | None | N | 0.224 | 0.114 | 0.348101942276 | gnomAD-2.1.1 | 1.52137E-04 | None | None | None | None | N | None | 0 | 1.21414E-03 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/I | 3349 |
Ig-24 |
5 | rs727503678 |
0.1203 | 0.098 | None | N | 0.224 | 0.114 | 0.348101942276 | gnomAD-3.1.2 | 7.23E-05 | None | None | None | None | N | None | 0 | 7.19707E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 3349 |
Ig-24 |
5 | rs727503678 |
0.1203 | 0.098 | None | N | 0.224 | 0.114 | 0.348101942276 | gnomAD-4.0.0 | 3.59354E-05 | None | None | None | None | N | None | 0 | 9.49937E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.60051E-05 |
| T/N | 3349 |
Ig-24 |
5 | rs727503678 |
0.1398 | -0.738 | 0.029 | N | 0.272 | 0.107 | 0.316494231283 | gnomAD-2.1.1 | 3.98E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.8E-06 | 0 |
| T/N | 3349 |
Ig-24 |
5 | rs727503678 |
0.1398 | -0.738 | 0.029 | N | 0.272 | 0.107 | 0.316494231283 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/N | 3349 |
Ig-24 |
5 | rs727503678 |
0.1398 | -0.738 | 0.029 | N | 0.272 | 0.107 | 0.316494231283 | gnomAD-4.0.0 | 6.57013E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46977E-05 | 0 | 0 |
| Q/H | 3469 |
Ig-25 |
5 | rs775464538 |
0.4849 | -0.522 | None | None | None | 0.422 | None | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.97E-06 | 0 |
| Q/H | 3469 |
Ig-25 |
5 | rs775464538 |
0.4849 | -0.522 | None | None | None | 0.422 | None | gnomAD-4.0.0 | 4.8027E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 6.31074E-06 | 0 | 0 |
| Q/P | 3469 |
Ig-25 |
5 | None | 0.8252 | None | None | None | None | 0.43 | None | gnomAD-4.0.0 | 1.6004E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44296E-05 | 0 |
| K/E | 3824 |
Ig-27 |
5 | None | 0.1815 | None | 0.193 | N | 0.238 | 0.161 | None | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/E | 3942 |
Ig-28 |
5 | rs2082461755 |
0.1309 | None | 0.625 | N | 0.306 | 0.177 | None | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.8226E-04 | 0 |
| T/A | 4610 |
Ig-29 |
5 | rs756313556 |
0.0866 | -0.865 | 0.019 | N | 0.217 | 0.181 | None | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.9E-06 | 0 |
| T/A | 4610 |
Ig-29 |
5 | rs756313556 |
0.0866 | -0.865 | 0.019 | N | 0.217 | 0.181 | None | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85793E-06 | 0 | 0 |
| T/I | 4610 |
Ig-29 |
5 | None | 0.093 | None | None | N | 0.153 | 0.147 | None | gnomAD-4.0.0 | 1.36838E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52029E-05 | None | 0 | 0 | 8.99437E-07 | 0 | 0 |
| T/K | 4610 |
Ig-29 |
5 | None | 0.0834 | None | None | N | 0.111 | 0.11 | None | gnomAD-4.0.0 | 6.84189E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99437E-07 | 0 | 0 |
| T/R | 4610 |
Ig-29 |
5 | rs748210214 |
0.0689 | -0.396 | None | N | 0.131 | 0.154 | None | gnomAD-2.1.1 | 3.62E-05 | None | None | None | None | N | None | 0 | 2.6093E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/R | 4610 |
Ig-29 |
5 | rs748210214 |
0.0689 | -0.396 | None | N | 0.131 | 0.154 | None | gnomAD-4.0.0 | 6.84189E-06 | None | None | None | None | N | None | 0 | 2.23634E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 4704 |
Ig-30 |
5 | rs775443847 |
0.2213 | -0.111 | 0.055 | N | 0.425 | 0.24 | 0.420447328233 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| R/G | 4704 |
Ig-30 |
5 | rs775443847 |
0.2213 | -0.111 | 0.055 | N | 0.425 | 0.24 | 0.420447328233 | gnomAD-4.0.0 | 1.59525E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43538E-05 | 0 |
| R/K | 4704 |
Ig-30 |
5 | None | 0.0765 | None | None | N | 0.127 | 0.123 | 0.236278675362 | gnomAD-4.0.0 | 1.59526E-06 | None | None | None | None | N | None | 5.66316E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 4892 |
Ig-32 |
5 | rs1200349655 |
0.2595 | 0.125 | 0.999 | N | 0.615 | 0.407 | 0.422524665647 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/E | 4892 |
Ig-32 |
5 | rs1200349655 |
0.2595 | 0.125 | 0.999 | N | 0.615 | 0.407 | 0.422524665647 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/E | 4892 |
Ig-32 |
5 | rs1200349655 |
0.2595 | 0.125 | 0.999 | N | 0.615 | 0.407 | 0.422524665647 | gnomAD-4.0.0 | 1.30139E-05 | None | None | None | None | N | None | 1.33422E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.61043E-05 | 0 | 1.60149E-05 |
| K/T | 4985 |
Ig-33 |
5 | rs750177841 |
0.5253 | -0.205 | 0.989 | N | 0.441 | 0.224 | 0.282575091529 | gnomAD-2.1.1 | 5.67E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 4.50586E-04 | None | 0 | 0 | 0 |
| K/T | 4985 |
Ig-33 |
5 | rs750177841 |
0.5253 | -0.205 | 0.989 | N | 0.441 | 0.224 | 0.282575091529 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.14422E-04 | 0 |
| K/T | 4985 |
Ig-33 |
5 | rs750177841 |
0.5253 | -0.205 | 0.989 | N | 0.441 | 0.224 | 0.282575091529 | gnomAD-4.0.0 | 2.45542E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.31504E-04 | 1.62543E-05 |
| K/E | 5079 |
Ig-34 |
5 | rs1327420984 |
0.1792 | None | 0.124 | D | 0.457 | 0.189 | 0.29132392195 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/E | 5079 |
Ig-34 |
5 | rs1327420984 |
0.1792 | None | 0.124 | D | 0.457 | 0.189 | 0.29132392195 | gnomAD-4.0.0 | 6.57056E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.46998E-05 | 0 | 0 |
| K/R | 5079 |
Ig-34 |
5 | None | 0.0686 | None | 0.001 | N | 0.174 | 0.066 | 0.178374595973 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 5172 |
Ig-35 |
5 | None | 0.6045 | None | 1.0 | D | 0.7 | 0.483 | 0.307648195649 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 1.94099E-04 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| E/K | 5265 |
Ig-36 |
5 | rs1370636944 |
0.1902 | 0.427 | 0.024 | D | 0.353 | 0.259 | 0.31291088546 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| E/K | 5265 |
Ig-36 |
5 | rs1370636944 |
0.1902 | 0.427 | 0.024 | D | 0.353 | 0.259 | 0.31291088546 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 5265 |
Ig-36 |
5 | rs1370636944 |
0.1902 | 0.427 | 0.024 | D | 0.353 | 0.259 | 0.31291088546 | gnomAD-4.0.0 | 4.34592E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.94335E-06 | 0 | 0 |
| E/K | 5547 |
Ig-39 |
5 | rs766334270 |
0.1071 | 0.154 | 0.064 | N | 0.184 | 0.226 | 0.156986980423 | gnomAD-2.1.1 | 4.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.57E-05 | None | 0 | 0 | 0 |
| E/K | 5547 |
Ig-39 |
5 | rs766334270 |
0.1071 | 0.154 | 0.064 | N | 0.184 | 0.226 | 0.156986980423 | gnomAD-4.0.0 | 6.89766E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.18433E-05 | 0 |
| K/T | 5641 |
Ig-40 |
5 | None | 0.1178 | None | 0.062 | N | 0.365 | 0.27 | 0.316198179892 | gnomAD-4.0.0 | 1.60697E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89712E-06 | 0 | 0 |
| K/E | 5734 |
Ig-41 |
5 | None | 0.1857 | None | 0.811 | N | 0.569 | 0.197 | 0.360961692134 | gnomAD-4.0.0 | 1.61419E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.0641E-05 |
| E/K | 5827 |
Ig-42 |
5 | rs753975878 |
0.1938 | -0.03 | 0.426 | N | 0.351 | 0.197 | None | gnomAD-2.1.1 | 4.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.55E-05 | None | 4.66E-05 | 6.22E-05 | 0 |
| E/K | 5827 |
Ig-42 |
5 | rs753975878 |
0.1938 | -0.03 | 0.426 | N | 0.351 | 0.197 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 2.41E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 5827 |
Ig-42 |
5 | rs753975878 |
0.1938 | -0.03 | 0.426 | N | 0.351 | 0.197 | None | gnomAD-4.0.0 | 1.67386E-05 | None | None | None | None | N | None | 1.33651E-05 | 1.66828E-05 | None | 0 | 0 | None | 1.56309E-05 | 0 | 1.69576E-05 | 4.39445E-05 | 0 |
| E/D | 6016 |
Ig-44 |
5 | None | 0.1812 | None | 0.016 | N | 0.205 | 0.043 | 0.281381271821 | gnomAD-4.0.0 | 1.61325E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.89665E-06 | 0 | 0 |
| K/E | 6109 |
Ig-45 |
5 | rs73973139 |
0.1397 | 0.161 | 0.64 | N | 0.433 | 0.176 | None | gnomAD-2.1.1 | 3.10033E-04 | None | None | None | None | N | None | 3.37107E-03 | 5.73E-05 | None | 0 | 0 | None | 0 | None | 0 | 7.88E-06 | 2.83607E-04 |
| K/E | 6109 |
Ig-45 |
5 | rs73973139 |
0.1397 | 0.161 | 0.64 | N | 0.433 | 0.176 | None | gnomAD-3.1.2 | 8.41131E-04 | None | None | None | None | N | None | 2.96686E-03 | 1.30924E-04 | 0 | 0 | 0 | None | 0 | 3.16456E-03 | 1.47E-05 | 0 | 4.78011E-04 |
| K/E | 6109 |
Ig-45 |
5 | rs73973139 |
0.1397 | 0.161 | 0.64 | N | 0.433 | 0.176 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 3.8E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| K/E | 6109 |
Ig-45 |
5 | rs73973139 |
0.1397 | 0.161 | 0.64 | N | 0.433 | 0.176 | None | gnomAD-4.0.0 | 2.00315E-04 | None | None | None | None | N | None | 3.81374E-03 | 8.3626E-05 | None | 0 | 0 | None | 0 | 3.30907E-04 | 7.63176E-06 | 0 | 3.36517E-04 |
| K/N | 6109 |
Ig-45 |
5 | rs556770980 |
0.4198 | -0.499 | 0.896 | N | 0.403 | 0.384 | 0.33340067248 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.96E-06 | 0 |
| K/N | 6109 |
Ig-45 |
5 | rs556770980 |
0.4198 | -0.499 | 0.896 | N | 0.403 | 0.384 | 0.33340067248 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/N | 6109 |
Ig-45 |
5 | rs556770980 |
0.4198 | -0.499 | 0.896 | N | 0.403 | 0.384 | 0.33340067248 | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| K/N | 6109 |
Ig-45 |
5 | rs556770980 |
0.4198 | -0.499 | 0.896 | N | 0.403 | 0.384 | 0.33340067248 | gnomAD-4.0.0 | 3.72104E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.0876E-06 | 0 | 0 |
| R/G | 6203 |
Ig-46 |
5 | None | 0.1974 | None | 0.801 | N | 0.382 | 0.43 | 0.564503807532 | gnomAD-4.0.0 | 1.59392E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86331E-06 | 0 | 0 |
| K/E | 6296 |
Ig-47 |
5 | None | 0.2212 | None | 0.016 | N | 0.139 | 0.262 | 0.309839678437 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| E/Q | 6389 |
Ig-48 |
5 | rs1256437537 |
0.1665 | 0.021 | 0.983 | D | 0.589 | 0.223 | 0.350524144436 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.58E-05 | None | 0 | None | 0 | 0 | 0 |
| E/Q | 6389 |
Ig-48 |
5 | rs1256437537 |
0.1665 | 0.021 | 0.983 | D | 0.589 | 0.223 | 0.350524144436 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/Q | 6389 |
Ig-48 |
5 | rs1256437537 |
0.1665 | 0.021 | 0.983 | D | 0.589 | 0.223 | 0.350524144436 | gnomAD-4.0.0 | 2.49858E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.24588E-05 | None | 0 | 0 | 1.71006E-06 | 1.10514E-05 | 0 |
| K/R | 6485 |
Ig-49 |
5 | None | 0.0841 | None | 0.996 | N | 0.512 | 0.181 | 0.290222751274 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| V/L | 6578 |
Ig-50 |
5 | rs2079625925 |
0.1257 | None | 0.002 | N | 0.072 | 0.197 | 0.284150004643 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.43E-05 | 0 | 0 | 0 | 0 |
| V/L | 6578 |
Ig-50 |
5 | rs2079625925 |
0.1257 | None | 0.002 | N | 0.072 | 0.197 | 0.284150004643 | gnomAD-4.0.0 | 6.57618E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 9.42685E-05 | 0 | 0 | 0 | 0 |
| V/M | 6578 |
Ig-50 |
5 | None | 0.1272 | None | 0.139 | N | 0.127 | 0.207 | 0.342631996419 | gnomAD-4.0.0 | 1.6504E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.9427E-06 | 0 | 0 |
| S/F | 6858 |
Ig-53 |
5 | rs1031134000 |
0.177 | None | 0.602 | N | 0.395 | 0.227 | 0.4897983601 | gnomAD-4.0.0 | 6.27089E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.28847E-06 | 0 | 1.6893E-05 |
| E/A | 6952 |
Ig-54 |
5 | rs779587161 |
0.3926 | 0.033 | 0.698 | D | 0.461 | 0.388 | 0.446111551642 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 6.51E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 6952 |
Ig-54 |
5 | None | 0.3488 | None | 0.822 | N | 0.471 | 0.356 | 0.41337360676 | gnomAD-4.0.0 | 1.38516E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.81787E-06 | 0 | 0 |
| R/L | 7048 |
Ig-55 |
5 | rs148072021 |
0.2894 | 0.466 | 0.975 | N | 0.54 | 0.433 | 0.587992605178 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
| R/L | 7048 |
Ig-55 |
5 | rs148072021 |
0.2894 | 0.466 | 0.975 | N | 0.54 | 0.433 | 0.587992605178 | gnomAD-4.0.0 | 2.73973E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.60091E-06 | 0 | 0 |
| R/Q | 7048 |
Ig-55 |
5 | rs148072021 |
0.1066 | 0.156 | 0.997 | N | 0.573 | 0.272 | None | gnomAD-2.1.1 | 2.03E-05 | None | None | None | None | N | None | 6.48E-05 | 2.91E-05 | None | 0 | 5.6E-05 | None | 0 | None | 0 | 1.8E-05 | 0 |
| R/Q | 7048 |
Ig-55 |
5 | rs148072021 |
0.1066 | 0.156 | 0.997 | N | 0.573 | 0.272 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 7048 |
Ig-55 |
5 | rs148072021 |
0.1066 | 0.156 | 0.997 | N | 0.573 | 0.272 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| R/Q | 7048 |
Ig-55 |
5 | rs148072021 |
0.1066 | 0.156 | 0.997 | N | 0.573 | 0.272 | None | gnomAD-4.0.0 | 6.20282E-06 | None | None | None | None | N | None | 4.00203E-05 | 1.66923E-05 | None | 0 | 0 | None | 0 | 1.65344E-04 | 2.54492E-06 | 1.10009E-05 | 1.60272E-05 |
| K/E | 7234 |
Ig-57 |
5 | rs1243074128 |
0.3089 | 0.64 | 0.999 | N | 0.616 | 0.254 | 0.465464902746 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.02E-06 | 0 |
| K/E | 7234 |
Ig-57 |
5 | rs1243074128 |
0.3089 | 0.64 | 0.999 | N | 0.616 | 0.254 | 0.465464902746 | gnomAD-4.0.0 | 3.19281E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.73227E-06 | 0 | 0 |
| K/R | 7234 |
Ig-57 |
5 | rs2078749547 |
0.1012 | None | 0.999 | N | 0.547 | 0.185 | 0.351180957027 | gnomAD-4.0.0 | 1.59662E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86625E-06 | 0 | 0 |
| T/M | 7327 |
Ig-58 |
5 | rs727504975 |
0.0802 | 0.097 | 0.328 | N | 0.34 | 0.266 | 0.414021929199 | gnomAD-2.1.1 | 1.55155E-04 | None | None | None | None | N | None | 0 | 5.89E-05 | None | 0 | 0 | None | 1.06823E-03 | None | 0 | 2.71E-05 | 1.69319E-04 |
| T/M | 7327 |
Ig-58 |
5 | rs727504975 |
0.0802 | 0.097 | 0.328 | N | 0.34 | 0.266 | 0.414021929199 | gnomAD-3.1.2 | 6.58E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 1.93274E-04 | None | 0 | 0 | 0 | 1.45108E-03 | 0 |
| T/M | 7327 |
Ig-58 |
5 | rs727504975 |
0.0802 | 0.097 | 0.328 | N | 0.34 | 0.266 | 0.414021929199 | gnomAD-4.0.0 | 8.75246E-05 | None | None | None | None | N | None | 2.67523E-05 | 3.3539E-05 | None | 0 | 2.23504E-05 | None | 0 | 0 | 1.61221E-05 | 1.24642E-03 | 6.42158E-05 |
| I/F | 7519 |
Ig-60 |
5 | rs146608139 |
0.2045 | -1.329 | 0.473 | N | 0.267 | 0.197 | 0.517819333224 | gnomAD-2.1.1 | 4.56E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.88E-05 | None | 0 | None | 0 | 0 | 0 |
| I/L | 7519 |
Ig-60 |
5 | rs146608139 |
0.1392 | -0.839 | 0.139 | N | 0.205 | 0.116 | None | gnomAD-2.1.1 | 4.56E-06 | None | None | None | None | I | None | 6.66E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| I/L | 7519 |
Ig-60 |
5 | rs146608139 |
0.1392 | -0.839 | 0.139 | N | 0.205 | 0.116 | None | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | I | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| I/L | 7519 |
Ig-60 |
5 | rs146608139 |
0.1392 | -0.839 | 0.139 | N | 0.205 | 0.116 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | I | None | 1.5E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| I/L | 7519 |
Ig-60 |
5 | rs146608139 |
0.1392 | -0.839 | 0.139 | N | 0.205 | 0.116 | None | gnomAD-4.0.0 | 4.43996E-06 | None | None | None | None | I | None | 9.52977E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 7612 |
Ig-61 |
5 | rs1553908654 |
0.4632 | 0.318 | 0.992 | N | 0.427 | 0.188 | 0.370608029945 | gnomAD-2.1.1 | 4.15E-06 | None | None | None | None | N | None | 0 | 2.98E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/E | 7612 |
Ig-61 |
5 | rs1553908654 |
0.4632 | 0.318 | 0.992 | N | 0.427 | 0.188 | 0.370608029945 | gnomAD-4.0.0 | 6.9122E-07 | None | None | None | None | N | None | 0 | 2.28165E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 7706 |
Ig-62 |
5 | None | 0.0727 | None | 0.001 | N | 0.083 | 0.136 | 0.178374595973 | gnomAD-4.0.0 | 4.80129E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.25001E-06 | 0 | 0 |
| R/C | 7989 |
Ig-65 |
5 | rs201653851 |
0.2057 | -0.171 | 1.0 | D | 0.595 | 0.493 | None | gnomAD-2.1.1 | 1.35735E-04 | None | None | None | None | N | None | 2.48098E-04 | 0 | None | 0 | 9.7366E-04 | None | 3.27E-05 | None | 0 | 9.38E-05 | 0 |
| R/C | 7989 |
Ig-65 |
5 | rs201653851 |
0.2057 | -0.171 | 1.0 | D | 0.595 | 0.493 | None | gnomAD-3.1.2 | 1.7759E-04 | None | None | None | None | N | None | 1.93237E-04 | 0 | 0 | 0 | 9.65624E-04 | None | 0 | 0 | 2.05888E-04 | 0 | 0 |
| R/C | 7989 |
Ig-65 |
5 | rs201653851 |
0.2057 | -0.171 | 1.0 | D | 0.595 | 0.493 | None | 1000 genomes | 3.99361E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| R/C | 7989 |
Ig-65 |
5 | rs201653851 |
0.2057 | -0.171 | 1.0 | D | 0.595 | 0.493 | None | gnomAD-4.0.0 | 1.7174E-04 | None | None | None | None | N | None | 1.73454E-04 | 0 | None | 0 | 7.13426E-04 | None | 0 | 0 | 1.75556E-04 | 7.68927E-05 | 2.88184E-04 |
| R/H | 7989 |
Ig-65 |
5 | rs898421060 |
0.1216 | -0.987 | 0.999 | N | 0.51 | 0.393 | 0.366659145958 | gnomAD-2.1.1 | 8.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| R/H | 7989 |
Ig-65 |
5 | rs898421060 |
0.1216 | -0.987 | 0.999 | N | 0.51 | 0.393 | 0.366659145958 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/H | 7989 |
Ig-65 |
5 | rs898421060 |
0.1216 | -0.987 | 0.999 | N | 0.51 | 0.393 | 0.366659145958 | gnomAD-4.0.0 | 8.06102E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.32948E-06 | 1.09861E-05 | 1.60164E-05 |
| R/P | 7989 |
Ig-65 |
5 | rs898421060 |
0.8534 | 0.161 | 0.999 | N | 0.573 | 0.427 | 0.598196723881 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| R/P | 7989 |
Ig-65 |
5 | rs898421060 |
0.8534 | 0.161 | 0.999 | N | 0.573 | 0.427 | 0.598196723881 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/P | 7989 |
Ig-65 |
5 | rs898421060 |
0.8534 | 0.161 | 0.999 | N | 0.573 | 0.427 | 0.598196723881 | gnomAD-4.0.0 | 6.578E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47072E-05 | 0 | 0 |
| L/Q | 8460 |
Ig-70 |
5 | None | 0.0889 | None | 0.021 | N | 0.249 | 0.141 | 0.598822425987 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/R | 8647 |
Ig-72 |
5 | None | 0.0735 | None | 0.001 | N | 0.209 | 0.078 | 0.243972157842 | gnomAD-4.0.0 | 1.37709E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80549E-06 | 0 | 0 |
| E/G | 8834 |
Ig-74 |
5 | None | 0.1618 | None | 0.92 | D | 0.377 | 0.31 | 0.533997809139 | gnomAD-4.0.0 | 1.5988E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.44957E-05 | 0 |
| R/G | 8930 |
Ig-75 |
5 | None | 0.4532 | None | 0.896 | N | 0.497 | 0.382 | 0.556540827966 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| R/T | 8930 |
Ig-75 |
5 | rs1206653316 |
0.5401 | 0.102 | 0.896 | N | 0.535 | 0.284 | 0.415313616471 | gnomAD-2.1.1 | 3.2E-05 | None | None | None | None | N | None | 1.1489E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| R/T | 8930 |
Ig-75 |
5 | rs1206653316 |
0.5401 | 0.102 | 0.896 | N | 0.535 | 0.284 | 0.415313616471 | gnomAD-3.1.2 | 6.61E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 8930 |
Ig-75 |
5 | rs1206653316 |
0.5401 | 0.102 | 0.896 | N | 0.535 | 0.284 | 0.415313616471 | gnomAD-4.0.0 | 3.04786E-06 | None | None | None | None | N | None | 3.50238E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20516E-06 | 0 | 0 |
| K/E | 9209 |
Ig-78 |
5 | rs148355969 |
0.1128 | 0.366 | 0.001 | N | 0.087 | 0.138 | None | gnomAD-2.1.1 | 8.23E-05 | None | None | None | None | N | None | 7.85838E-04 | 1.1334E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/E | 9209 |
Ig-78 |
5 | rs148355969 |
0.1128 | 0.366 | 0.001 | N | 0.087 | 0.138 | None | gnomAD-3.1.2 | 2.10333E-04 | None | None | None | None | N | None | 7.47997E-04 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/E | 9209 |
Ig-78 |
5 | rs148355969 |
0.1128 | 0.366 | 0.001 | N | 0.087 | 0.138 | None | 1000 genomes | 7.98722E-04 | None | None | None | None | N | None | 3E-03 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| K/E | 9209 |
Ig-78 |
5 | rs148355969 |
0.1128 | 0.366 | 0.001 | N | 0.087 | 0.138 | None | gnomAD-4.0.0 | 4.89684E-05 | None | None | None | None | N | None | 9.46414E-04 | 1.00057E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.20184E-05 |
| K/R | 9209 |
Ig-78 |
5 | rs775941896 |
0.0799 | -0.186 | None | N | 0.093 | 0.063 | 0.162503812791 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| K/R | 9209 |
Ig-78 |
5 | rs775941896 |
0.0799 | -0.186 | None | N | 0.093 | 0.063 | 0.162503812791 | gnomAD-4.0.0 | 1.59251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8609E-06 | 0 | 0 |
| R/L | 9305 |
Ig-79 |
5 | None | 0.3063 | None | 0.954 | N | 0.41 | 0.321 | 0.631068764991 | gnomAD-4.0.0 | 6.87758E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.17697E-05 | 0 |
| R/Q | 9305 |
Ig-79 |
5 | rs397517527 |
0.1244 | 0.235 | 0.958 | N | 0.383 | 0.161 | 0.216624796971 | gnomAD-2.1.1 | 1.95387E-04 | None | None | None | None | N | None | 0 | 1.27001E-03 | None | 0 | 0 | None | 3.37E-05 | None | 0 | 3.58E-05 | 0 |
| R/Q | 9305 |
Ig-79 |
5 | rs397517527 |
0.1244 | 0.235 | 0.958 | N | 0.383 | 0.161 | 0.216624796971 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/Q | 9305 |
Ig-79 |
5 | rs397517527 |
0.1244 | 0.235 | 0.958 | N | 0.383 | 0.161 | 0.216624796971 | gnomAD-4.0.0 | 4.17173E-05 | None | None | None | None | N | None | 0 | 8.42318E-04 | None | 0 | 0 | None | 1.56622E-05 | 0 | 9.36005E-06 | 2.22762E-05 | 4.82532E-05 |
| I/F | 9401 |
Ig-80 |
5 | None | 0.1588 | None | 0.772 | None | 0.281 | 0.311 | 0.463586170655 | gnomAD-4.0.0 | 1.59235E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 2.41546E-04 | 0 | 0 | 0 |
| K/N | 9904 |
Ig-84 |
5 | rs2075586550 |
0.7723 | None | 0.896 | None | 0.507 | 0.344 | 0.284150004643 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| K/N | 9904 |
Ig-84 |
5 | rs2075586550 |
0.7723 | None | 0.896 | None | 0.507 | 0.344 | 0.284150004643 | gnomAD-4.0.0 | 6.57151E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.07211E-04 | 0 |
| K/Q | 9904 |
Ig-84 |
5 | None | 0.2923 | None | 0.968 | None | 0.55 | 0.221 | 0.296329037015 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| K/R | 9904 |
Ig-84 |
5 | rs1268665035 |
0.0998 | None | 0.026 | None | 0.165 | 0.103 | 0.3571064206 | gnomAD-4.0.0 | 1.60131E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43753E-05 | 0 |
| K/T | 9904 |
Ig-84 |
5 | None | 0.5561 | None | 0.811 | None | 0.55 | 0.255 | 0.360565625551 | gnomAD-4.0.0 | 1.60131E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86354E-06 | 0 | 0 |
| R/G | 9993 |
Ig-85 |
5 | None | 0.2886 | None | 0.911 | None | 0.338 | 0.314 | 0.643257150579 | gnomAD-4.0.0 | 6.8446E-07 | None | None | None | None | N | None | 2.99043E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 9993 |
Ig-85 |
5 | rs575360239 |
0.0845 | -0.166 | 0.469 | None | 0.172 | 0.187 | 0.156986980423 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| R/Q | 9993 |
Ig-85 |
5 | rs575360239 |
0.0845 | -0.166 | 0.469 | None | 0.172 | 0.187 | 0.156986980423 | gnomAD-4.0.0 | 3.0992E-06 | None | None | None | None | N | None | 1.33316E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.5437E-06 | 1.09844E-05 | 0 |
| R/W | 9993 |
Ig-85 |
5 | rs375415014 |
0.2442 | -0.057 | 0.999 | None | 0.42 | 0.405 | None | gnomAD-2.1.1 | 1.43E-05 | None | None | None | None | N | None | 8.26E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.56E-05 | 0 |
| R/W | 9993 |
Ig-85 |
5 | rs375415014 |
0.2442 | -0.057 | 0.999 | None | 0.42 | 0.405 | None | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 4.82E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| R/W | 9993 |
Ig-85 |
5 | rs375415014 |
0.2442 | -0.057 | 0.999 | None | 0.42 | 0.405 | None | gnomAD-4.0.0 | 2.29357E-05 | None | None | None | None | N | None | 2.67051E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.79802E-05 | 0 | 3.20318E-05 |
| K/T | 10082 |
Ig-86 |
5 | rs2075208868 |
0.8487 | None | 0.83 | None | 0.761 | 0.243 | 0.336647302497 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/T | 10082 |
Ig-86 |
5 | rs2075208868 |
0.8487 | None | 0.83 | None | 0.761 | 0.243 | 0.336647302497 | gnomAD-4.0.0 | 6.57004E-06 | None | None | None | None | N | None | 2.41371E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/N | 13784 |
Ig-88 |
5 | None | 0.7067 | None | 0.638 | D | 0.54 | 0.248 | 0.274366138417 | gnomAD-4.0.0 | 3.32251E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 3.03776E-05 | 0 |
| K/R | 13784 |
Ig-88 |
5 | None | 0.112 | None | 0.002 | N | 0.407 | 0.144 | 0.376039117802 | gnomAD-4.0.0 | 1.66562E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.52527E-05 | 0 |
| K/N | 13878 |
Ig-89 |
3 | None | 0.8079 | None | 0.999 | D | 0.66 | 0.232 | 0.17258766438 | gnomAD-4.0.0 | 6.89888E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.04254E-07 | 0 | 0 |
| V/M | 14058 |
Ig-91 |
5 | rs774014126 |
0.1967 | -0.276 | 0.999 | N | 0.545 | 0.267 | 0.479818277033 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| V/M | 14058 |
Ig-91 |
5 | rs774014126 |
0.1967 | -0.276 | 0.999 | N | 0.545 | 0.267 | 0.479818277033 | gnomAD-4.0.0 | 1.5925E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.8604E-06 | 0 | 0 |
| S/L | 14146 |
Ig-92 |
5 | rs760628135 |
0.08 | 0.261 | 0.012 | N | 0.341 | 0.262 | 0.312001716656 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| S/L | 14146 |
Ig-92 |
5 | rs760628135 |
0.08 | 0.261 | 0.012 | N | 0.341 | 0.262 | 0.312001716656 | gnomAD-4.0.0 | 1.59317E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86094E-06 | 0 | 0 |
| K/E | 14323 |
Ig-94 |
5 | None | 0.4391 | None | 0.435 | N | 0.411 | 0.168 | 0.149567049428 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/N | 14323 |
Ig-94 |
5 | None | 0.6316 | None | 0.651 | N | 0.305 | 0.101 | 0.115124310173 | gnomAD-4.0.0 | 1.59326E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43728E-05 | 0 |
| T/A | 14412 |
Ig-95 |
5 | rs185007509 |
0.1213 | -0.705 | 0.999 | N | 0.545 | 0.367 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 14412 |
Ig-95 |
5 | rs185007509 |
0.1213 | -0.705 | 0.999 | N | 0.545 | 0.367 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 0 | 0 | None | None | 1E-03 | 0 | None | None | None | 0 | None |
| T/A | 14412 |
Ig-95 |
5 | rs185007509 |
0.1213 | -0.705 | 0.999 | N | 0.545 | 0.367 | None | gnomAD-4.0.0 | 2.56442E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 4.85885E-05 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 14501 |
Ig-96 |
5 | rs764500643 |
0.1173 | -0.624 | 0.005 | N | 0.112 | 0.134 | None | gnomAD-2.1.1 | 3.54E-05 | None | None | None | None | N | None | 3.90761E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 14501 |
Ig-96 |
5 | rs764500643 |
0.1173 | -0.624 | 0.005 | N | 0.112 | 0.134 | None | gnomAD-3.1.2 | 5.93E-05 | None | None | None | None | N | None | 2.17633E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 14501 |
Ig-96 |
5 | rs764500643 |
0.1173 | -0.624 | 0.005 | N | 0.112 | 0.134 | None | gnomAD-4.0.0 | 1.25638E-05 | None | None | None | None | N | None | 2.70205E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/I | 14501 |
Ig-96 |
5 | rs115825044 |
0.1944 | 0.197 | 0.934 | N | 0.441 | 0.248 | 0.459642846412 | gnomAD-2.1.1 | 1.78E-05 | None | None | None | None | N | None | 0 | 9.87E-05 | None | 0 | 0 | None | 0 | None | 0 | 9.8E-06 | 0 |
| T/I | 14501 |
Ig-96 |
5 | rs115825044 |
0.1944 | 0.197 | 0.934 | N | 0.441 | 0.248 | 0.459642846412 | gnomAD-4.0.0 | 2.08197E-06 | None | None | None | None | N | None | 0 | 4.85555E-05 | None | 0 | 0 | None | 0 | 0 | 9.06645E-07 | 0 | 0 |
| T/N | 14501 |
Ig-96 |
5 | None | 0.1434 | -0.324 | 0.891 | N | 0.368 | 0.213 | 0.403328974453 | gnomAD-2.1.1 | 5.08E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.19369E-04 | None | 0 | None | 0 | 1.7E-05 | 0 |
| T/N | 14501 |
Ig-96 |
5 | None | 0.1434 | -0.324 | 0.891 | N | 0.368 | 0.213 | 0.403328974453 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.93648E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 14501 |
Ig-96 |
5 | None | 0.1434 | -0.324 | 0.891 | N | 0.368 | 0.213 | 0.403328974453 | gnomAD-4.0.0 | 1.1928E-05 | None | None | None | None | N | None | 1.34953E-05 | 0 | None | 0 | 2.93507E-04 | None | 0 | 0 | 4.27009E-06 | 0 | 0 |
| T/S | 14501 |
Ig-96 |
5 | rs115825044 |
0.1599 | -0.651 | 0.454 | N | 0.373 | 0.211 | 0.156986980423 | gnomAD-2.1.1 | 1.21208E-04 | None | None | None | None | N | None | 1.03645E-03 | 9.61E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.51E-06 | 4.55512E-04 |
| T/S | 14501 |
Ig-96 |
5 | rs115825044 |
0.1599 | -0.651 | 0.454 | N | 0.373 | 0.211 | 0.156986980423 | gnomAD-3.1.2 | 4.14626E-04 | None | None | None | None | N | None | 1.23165E-03 | 4.59619E-04 | 0 | 0 | 0 | None | 0 | 0 | 4.41E-05 | 0 | 9.61538E-04 |
| T/S | 14501 |
Ig-96 |
5 | rs115825044 |
0.1599 | -0.651 | 0.454 | N | 0.373 | 0.211 | 0.156986980423 | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 3E-03 | 1.4E-03 | None | None | 0 | 0 | None | None | None | 0 | None |
| T/S | 14501 |
Ig-96 |
5 | rs115825044 |
0.1599 | -0.651 | 0.454 | N | 0.373 | 0.211 | 0.156986980423 | gnomAD-4.0.0 | 1.04206E-04 | None | None | None | None | N | None | 1.29345E-03 | 2.12615E-04 | None | 0 | 0 | None | 0 | 8.35561E-04 | 3.15989E-05 | 0 | 2.59648E-04 |
| G/R | 14590 |
Ig-97 |
5 | None | 0.1841 | None | 0.028 | N | 0.368 | 0.205 | 0.473538153929 | gnomAD-4.0.0 | 7.54763E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.93065E-05 | 0 | 9.00455E-06 | 0 | 0 |
| R/Q | 14679 |
Ig-98 |
5 | rs369709751 |
0.1366 | 0.407 | 0.999 | N | 0.66 | 0.308 | None | gnomAD-2.1.1 | 1.04341E-04 | None | None | None | None | N | None | 8.28E-05 | 1.43275E-04 | None | 0 | 3.64166E-04 | None | 3.32E-05 | None | 4.01E-05 | 1.02092E-04 | 0 |
| R/Q | 14679 |
Ig-98 |
5 | rs369709751 |
0.1366 | 0.407 | 0.999 | N | 0.66 | 0.308 | None | gnomAD-3.1.2 | 9.87E-05 | None | None | None | None | N | None | 4.83E-05 | 1.96721E-04 | 0 | 0 | 1.94401E-04 | None | 0 | 0 | 1.32376E-04 | 0 | 0 |
| R/Q | 14679 |
Ig-98 |
5 | rs369709751 |
0.1366 | 0.407 | 0.999 | N | 0.66 | 0.308 | None | gnomAD-4.0.0 | 7.26008E-05 | None | None | None | None | N | None | 6.68986E-05 | 1.343E-04 | None | 0 | 2.01387E-04 | None | 0 | 1.64908E-04 | 7.54789E-05 | 1.1038E-05 | 6.41416E-05 |
| R/K | 14768 |
Ig-99 |
4 | None | 0.1645 | None | 0.37 | N | 0.231 | 0.155 | 0.200317383148 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.17284E-04 | 0 | 0 | 3.66327E-05 |
| R/K | 14946 |
Ig-101 |
5 | rs1291314776 |
0.0976 | 0.031 | 0.002 | N | 0.146 | 0.126 | 0.298056030225 | gnomAD-2.1.1 | 4.28E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.46E-06 | 0 |
| R/K | 14946 |
Ig-101 |
5 | rs1291314776 |
0.0976 | 0.031 | 0.002 | N | 0.146 | 0.126 | 0.298056030225 | gnomAD-4.0.0 | 4.13487E-06 | None | None | None | None | N | None | 3.01277E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.51743E-06 | 0 | 0 |
| K/R | 15035 |
Ig-102 |
5 | None | 0.0894 | None | 0.999 | N | 0.543 | 0.301 | 0.444102476654 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| S/A | 15124 |
Ig-103 |
5 | None | 0.0822 | None | 0.007 | N | 0.109 | 0.053 | 0.194818534648 | gnomAD-4.0.0 | 1.59693E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86466E-06 | 0 | 0 |
| V/I | 15212 |
Ig-104 |
5 | None | 0.0801 | None | 0.003 | N | 0.123 | 0.084 | 0.401042353794 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| E/D | 15306 |
Ig-105 |
5 | rs761792062 |
0.2468 | -0.534 | 0.993 | N | 0.463 | 0.201 | 0.353761421236 | gnomAD-2.1.1 | 1.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.71E-05 | 0 |
| E/D | 15306 |
Ig-105 |
5 | rs761792062 |
0.2468 | -0.534 | 0.993 | N | 0.463 | 0.201 | 0.353761421236 | gnomAD-4.0.0 | 1.2352E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.62151E-05 | 0 | 0 |
| E/K | 15306 |
Ig-105 |
5 | rs774339883 |
0.369 | 0.131 | 0.993 | N | 0.505 | 0.339 | 0.348764635752 | gnomAD-2.1.1 | 1.23E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.71E-05 | 0 |
| E/K | 15306 |
Ig-105 |
5 | rs774339883 |
0.369 | 0.131 | 0.993 | N | 0.505 | 0.339 | 0.348764635752 | gnomAD-3.1.2 | 6.59E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 15306 |
Ig-105 |
5 | rs774339883 |
0.369 | 0.131 | 0.993 | N | 0.505 | 0.339 | 0.348764635752 | gnomAD-4.0.0 | 3.79034E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.09315E-05 | 0 | 1.60736E-05 |
| E/G | 15395 |
Ig-106 |
5 | None | 0.2129 | None | 0.669 | N | 0.483 | 0.208 | 0.36036328697 | gnomAD-4.0.0 | 6.91192E-07 | None | None | None | None | N | None | 3.02828E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 15395 |
Ig-106 |
5 | rs771991019 |
0.1461 | -0.9 | 0.669 | N | 0.424 | 0.247 | 0.271763555656 | gnomAD-2.1.1 | 4.18E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.62E-05 | None | 0 | None | 0 | 0 | 0 |
| E/K | 15395 |
Ig-106 |
5 | rs771991019 |
0.1461 | -0.9 | 0.669 | N | 0.424 | 0.247 | 0.271763555656 | gnomAD-4.0.0 | 4.1461E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 7.60109E-05 | None | 0 | 0 | 0 | 2.38624E-05 | 1.67532E-05 |
| R/K | 15484 |
Ig-107 |
5 | rs72677229 |
0.1963 | -0.21 | 0.997 | N | 0.521 | 0.34 | None | gnomAD-2.1.1 | 1.91319E-04 | None | None | None | None | N | None | 0 | 5.74E-05 | None | 0 | 0 | None | 0 | None | 1.20443E-04 | 3.78997E-04 | 0 |
| R/K | 15484 |
Ig-107 |
5 | rs72677229 |
0.1963 | -0.21 | 0.997 | N | 0.521 | 0.34 | None | gnomAD-3.1.2 | 2.30597E-04 | None | None | None | None | N | None | 7.25E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 4.7142E-04 | 0 | 0 |
| R/K | 15484 |
Ig-107 |
5 | rs72677229 |
0.1963 | -0.21 | 0.997 | N | 0.521 | 0.34 | None | gnomAD-4.0.0 | 2.99292E-04 | None | None | None | None | N | None | 8.03772E-05 | 0 | None | 0 | 2.23864E-05 | None | 4.69763E-05 | 0 | 3.91147E-04 | 0 | 1.76542E-04 |
| R/M | 15484 |
Ig-107 |
5 | rs72677229 |
0.6675 | -0.133 | 1.0 | N | 0.76 | 0.481 | 0.463586170655 | gnomAD-2.1.1 | 8.14E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.8E-05 | 0 |
| R/M | 15484 |
Ig-107 |
5 | rs72677229 |
0.6675 | -0.133 | 1.0 | N | 0.76 | 0.481 | 0.463586170655 | gnomAD-4.0.0 | 3.42774E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 5.21921E-04 | 1.80066E-06 | 0 | 0 |
| T/I | 15572 |
Ig-108 |
5 | rs1398854469 |
0.2308 | None | 0.993 | N | 0.701 | 0.404 | 0.480497669815 | gnomAD-4.0.0 | 1.37204E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80094E-06 | 0 | 0 |
| T/R | 15572 |
Ig-108 |
5 | None | 0.2967 | None | 0.997 | N | 0.685 | 0.43 | 0.528662862717 | gnomAD-4.0.0 | 6.86021E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16474E-05 | 0 |
| R/Q | 17972 |
Ig-114 |
5 | rs377169251 |
0.1892 | -0.124 | 0.985 | N | 0.586 | 0.265 | None | gnomAD-2.1.1 | 1.27E-05 | None | None | None | None | N | None | 6.69E-05 | 0 | None | 0 | 1.16198E-04 | None | 0 | None | 0 | 0 | 0 |
| R/Q | 17972 |
Ig-114 |
5 | rs377169251 |
0.1892 | -0.124 | 0.985 | N | 0.586 | 0.265 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.84E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/Q | 17972 |
Ig-114 |
5 | rs377169251 |
0.1892 | -0.124 | 0.985 | N | 0.586 | 0.265 | None | gnomAD-4.0.0 | 1.06232E-05 | None | None | None | None | N | None | 2.69121E-05 | 0 | None | 0 | 4.50897E-05 | None | 0 | 0 | 7.66943E-06 | 3.36768E-05 | 1.61723E-05 |
| R/C | 20483 |
Ig-121 |
5 | rs770139489 |
0.5403 | -0.407 | 1.0 | N | 0.679 | 0.348 | 0.509053020717 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.46E-05 | 0 |
| R/C | 20483 |
Ig-121 |
5 | rs770139489 |
0.5403 | -0.407 | 1.0 | N | 0.679 | 0.348 | 0.509053020717 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.89E-05 | 0 | 0 |
| R/C | 20483 |
Ig-121 |
5 | rs770139489 |
0.5403 | -0.407 | 1.0 | N | 0.679 | 0.348 | 0.509053020717 | gnomAD-4.0.0 | 6.99394E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.48305E-06 | 0 | 0 |
| R/H | 20483 |
Ig-121 |
5 | rs748693257 |
0.2673 | -0.904 | 0.641 | N | 0.306 | 0.19 | 0.110078149338 | gnomAD-2.1.1 | 9.29E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.77E-05 | None | 0 | None | 0 | 1E-05 | 0 |
| R/H | 20483 |
Ig-121 |
5 | rs748693257 |
0.2673 | -0.904 | 0.641 | N | 0.306 | 0.19 | 0.110078149338 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| R/H | 20483 |
Ig-121 |
5 | rs748693257 |
0.2673 | -0.904 | 0.641 | N | 0.306 | 0.19 | 0.110078149338 | gnomAD-4.0.0 | 2.41634E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.74673E-05 | None | 0 | 0 | 2.67258E-05 | 2.42324E-05 | 3.29685E-05 |
| R/L | 20483 |
Ig-121 |
5 | rs748693257 |
0.6744 | None | 0.999 | N | 0.539 | 0.405 | 0.383256108077 | gnomAD-4.0.0 | 7.03911E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.15771E-07 | 0 | 0 |
| L/M | 20773 |
Ig-122 |
5 | None | 0.1735 | -0.152 | 0.76 | N | 0.385 | 0.045 | None | gnomAD-2.1.1 | 9.66E-05 | None | None | None | None | N | None | 9.92228E-04 | 5.67E-05 | None | 0 | 0 | None | 0 | None | 0 | 7.84E-06 | 0 |
| L/M | 20773 |
Ig-122 |
5 | None | 0.1735 | -0.152 | 0.76 | N | 0.385 | 0.045 | None | gnomAD-3.1.2 | 2.6313E-04 | None | None | None | None | N | None | 9.6595E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/M | 20773 |
Ig-122 |
5 | None | 0.1735 | -0.152 | 0.76 | N | 0.385 | 0.045 | None | 1000 genomes | 1.99681E-04 | None | None | None | None | N | None | 8E-04 | 0 | None | None | 0 | 0 | None | None | None | 0 | None |
| L/M | 20773 |
Ig-122 |
5 | None | 0.1735 | -0.152 | 0.76 | N | 0.385 | 0.045 | None | gnomAD-4.0.0 | 4.5866E-05 | None | None | None | None | N | None | 9.33508E-04 | 1.66767E-05 | None | 0 | 0 | None | 0 | 0 | 8.47716E-07 | 0 | 3.20184E-05 |
| L/P | 20773 |
Ig-122 |
5 | rs2049745835 |
0.8756 | None | 0.997 | N | 0.671 | 0.492 | 0.720495031645 | gnomAD-4.0.0 | 7.95981E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.39121E-04 | None | 0 | 0 | 0 | 0 | 0 |
| L/V | 20773 |
Ig-122 |
5 | rs375173874 |
0.1561 | None | 0.046 | N | 0.307 | 0.052 | 0.233785782151 | gnomAD-4.0.0 | 3.4217E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49772E-06 | 0 | 0 |
| D/N | 22954 |
Ig-128 |
5 | None | 0.0938 | None | 0.967 | N | 0.651 | 0.339 | 0.326074293725 | gnomAD-4.0.0 | 6.92941E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.09099E-07 | 0 | 0 |
| E/D | 23349 |
Ig-129 |
5 | rs774136558 |
0.1936 | -0.159 | 0.025 | N | 0.363 | 0.064 | 0.21737058555 | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.1435E-04 | None | 0 | None | 0 | 0 | 0 |
| E/D | 23349 |
Ig-129 |
5 | rs774136558 |
0.1936 | -0.159 | 0.025 | N | 0.363 | 0.064 | 0.21737058555 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 3.87297E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/D | 23349 |
Ig-129 |
5 | rs774136558 |
0.1936 | -0.159 | 0.025 | N | 0.363 | 0.064 | 0.21737058555 | gnomAD-4.0.0 | 5.57836E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.00857E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 23349 |
Ig-129 |
5 | rs397517682 |
0.7337 | 0.673 | 0.979 | N | 0.536 | 0.313 | None | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | I | None | 0 | 0 | None | 0 | 5.15E-05 | None | 3.27E-05 | None | 0 | 7.82E-06 | 0 |
| E/K | 23349 |
Ig-129 |
5 | rs397517682 |
0.7337 | 0.673 | 0.979 | N | 0.536 | 0.313 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 1.93723E-04 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 23349 |
Ig-129 |
5 | rs397517682 |
0.7337 | 0.673 | 0.979 | N | 0.536 | 0.313 | None | gnomAD-4.0.0 | 4.95879E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 2.23204E-05 | None | 0 | 0 | 1.6955E-06 | 4.3929E-05 | 1.60149E-05 |
| K/Q | 23641 |
Ig-130 |
5 | rs778715011 |
0.2104 | -0.636 | 0.817 | N | 0.291 | 0.159 | 0.223847106136 | gnomAD-2.1.1 | 1.22E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.68E-05 | None | 6.57E-05 | None | 0 | 0 | 0 |
| K/Q | 23641 |
Ig-130 |
5 | rs778715011 |
0.2104 | -0.636 | 0.817 | N | 0.291 | 0.159 | 0.223847106136 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| K/Q | 23641 |
Ig-130 |
5 | rs778715011 |
0.2104 | -0.636 | 0.817 | N | 0.291 | 0.159 | 0.223847106136 | gnomAD-4.0.0 | 8.06037E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.24235E-05 | None | 0 | 0 | 2.5435E-06 | 9.89381E-05 | 0 |
| V/I | 24033 |
Ig-131 |
5 | rs771227294 |
0.0772 | None | None | N | 0.273 | 0.086 | 0.273503213844 | gnomAD-4.0.0 | 1.59202E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43312E-05 | 0 |
| L/F | 24720 |
Ig-133 |
5 | None | 0.3017 | None | 0.997 | N | 0.511 | 0.404 | 0.710867761551 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| P/L | 25802 |
Ig-136 |
5 | None | 0.123 | None | 0.014 | N | 0.456 | 0.217 | 0.321672782286 | gnomAD-4.0.0 | 2.05337E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69898E-06 | 0 | 0 |
| P/A | 26197 |
Ig-137 |
5 | rs747052899 |
0.1747 | None | 0.058 | N | 0.413 | 0.22 | 0.17258766438 | gnomAD-4.0.0 | 3.42842E-06 | None | None | None | None | N | None | 2.99724E-05 | 0 | None | 0 | 0 | None | 0 | 1.74095E-04 | 2.70176E-06 | 0 | 0 |
| P/T | 26197 |
Ig-137 |
5 | rs747052899 |
0.2314 | -1.66 | 0.698 | N | 0.638 | 0.413 | 0.40528724903 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 6.48E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| P/T | 26197 |
Ig-137 |
5 | rs747052899 |
0.2314 | -1.66 | 0.698 | N | 0.638 | 0.413 | 0.40528724903 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| P/T | 26197 |
Ig-137 |
5 | rs747052899 |
0.2314 | -1.66 | 0.698 | N | 0.638 | 0.413 | 0.40528724903 | gnomAD-4.0.0 | 5.58866E-06 | None | None | None | None | N | None | 6.68771E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 3.39452E-06 | 0 | 0 |
| P/L | 27279 |
Ig-140 |
2 | rs776798967 |
0.159 | None | 0.997 | N | 0.555 | 0.438 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/L | 27279 |
Ig-140 |
2 | rs776798967 |
0.159 | None | 0.997 | N | 0.555 | 0.438 | None | gnomAD-4.0.0 | 1.31536E-05 | None | None | None | None | N | None | 4.82905E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| P/R | 27279 |
Ig-140 |
2 | rs776798967 |
0.2738 | 0.108 | 0.997 | D | 0.576 | 0.391 | 0.46682414995 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65728E-04 |
| P/R | 27279 |
Ig-140 |
2 | rs776798967 |
0.2738 | 0.108 | 0.997 | D | 0.576 | 0.391 | 0.46682414995 | gnomAD-4.0.0 | 1.59181E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02407E-05 |
| P/S | 27279 |
Ig-140 |
2 | rs1323358528 |
0.1831 | -0.416 | 0.418 | N | 0.271 | 0.239 | 0.227260227426 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.65782E-04 |
| P/S | 27279 |
Ig-140 |
2 | rs1323358528 |
0.1831 | -0.416 | 0.418 | N | 0.271 | 0.239 | 0.227260227426 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78011E-04 |
| D/A | 27680 |
Ig-141 |
5 | None | 0.4651 | None | 0.919 | N | 0.653 | 0.355 | 0.461058313273 | gnomAD-4.0.0 | 1.59136E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| D/E | 27680 |
Ig-141 |
5 | rs754885118 |
0.2242 | 0.001 | 0.958 | N | 0.533 | 0.233 | 0.199424873507 | gnomAD-2.1.1 | 7.85E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.12751E-03 | None | 0 | None | 0 | 0 | 0 |
| D/E | 27680 |
Ig-141 |
5 | rs754885118 |
0.2242 | 0.001 | 0.958 | N | 0.533 | 0.233 | 0.199424873507 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 3.86548E-04 | None | 0 | 0 | 0 | 0 | 0 |
| D/E | 27680 |
Ig-141 |
5 | rs754885118 |
0.2242 | 0.001 | 0.958 | N | 0.533 | 0.233 | 0.199424873507 | gnomAD-4.0.0 | 6.81694E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.22856E-04 | None | 0 | 0 | 0 | 0 | 1.60123E-05 |
| D/G | 27680 |
Ig-141 |
5 | rs1431056112 |
0.5396 | -0.298 | 0.919 | N | 0.675 | 0.364 | 0.303781844768 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| D/G | 27680 |
Ig-141 |
5 | rs1431056112 |
0.5396 | -0.298 | 0.919 | N | 0.675 | 0.364 | 0.303781844768 | gnomAD-4.0.0 | 6.36543E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 4.82625E-04 | 2.85874E-06 | 0 | 3.02462E-05 |
| E/K | 28759 |
Ig-144 |
5 | rs1180434242 |
0.2996 | 0.361 | 0.722 | N | 0.527 | 0.221 | 0.302459207581 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 1.14758E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 28759 |
Ig-144 |
5 | rs1180434242 |
0.2996 | 0.361 | 0.722 | N | 0.527 | 0.221 | 0.302459207581 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 28759 |
Ig-144 |
5 | rs1180434242 |
0.2996 | 0.361 | 0.722 | N | 0.527 | 0.221 | 0.302459207581 | gnomAD-4.0.0 | 2.56881E-06 | None | None | None | None | N | None | 1.69125E-05 | 0 | None | 0 | 2.42448E-05 | None | 0 | 0 | 0 | 0 | 0 |
| N/H | 31222 |
Ig-151 |
5 | rs760845662 |
0.105 | -0.394 | 0.009 | N | 0.24 | 0.13 | 0.141422826196 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| N/H | 31222 |
Ig-151 |
5 | rs760845662 |
0.105 | -0.394 | 0.009 | N | 0.24 | 0.13 | 0.141422826196 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | I | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| N/H | 31222 |
Ig-151 |
5 | rs760845662 |
0.105 | -0.394 | 0.009 | N | 0.24 | 0.13 | 0.141422826196 | gnomAD-4.0.0 | 3.71841E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.08587E-06 | 0 | 0 |
| N/S | 31222 |
Ig-151 |
5 | rs1559164640 |
0.0772 | None | 0.334 | N | 0.404 | 0.152 | 0.12205267543 | gnomAD-4.0.0 | 3.42129E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.49751E-06 | 0 | 0 |
| N/Y | 31222 |
Ig-151 |
5 | None | 0.2587 | None | 0.681 | N | 0.449 | 0.257 | 0.485348376517 | gnomAD-4.0.0 | 6.8426E-07 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99514E-07 | 0 | 0 |
| M/T | 32311 |
Ig-154 |
5 | None | 0.4834 | None | 0.425 | N | 0.392 | 0.219 | 0.579236789951 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| M/V | 32311 |
Ig-154 |
5 | rs727504981 |
0.0822 | 0.307 | 0.003 | N | 0.149 | 0.105 | 0.300449992093 | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | N | None | 0 | 2.93E-05 | None | 0 | 0 | None | 0 | None | 0 | 2.7E-05 | 0 |
| M/V | 32311 |
Ig-154 |
5 | rs727504981 |
0.0822 | 0.307 | 0.003 | N | 0.149 | 0.105 | 0.300449992093 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| M/V | 32311 |
Ig-154 |
5 | rs727504981 |
0.0822 | 0.307 | 0.003 | N | 0.149 | 0.105 | 0.300449992093 | gnomAD-4.0.0 | 1.55515E-05 | None | None | None | None | N | None | 0 | 1.67588E-05 | None | 0 | 0 | None | 0 | 1.64908E-04 | 1.95703E-05 | 0 | 0 |
| K/I | 33105 |
Ig-156 |
5 | rs1196579817 |
0.3405 | 0.703 | 0.185 | N | 0.381 | 0.275 | 0.578164481777 | gnomAD-2.1.1 | 4.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.01E-06 | 0 |
| K/I | 33105 |
Ig-156 |
5 | rs1196579817 |
0.3405 | 0.703 | 0.185 | N | 0.381 | 0.275 | 0.578164481777 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/I | 33105 |
Ig-156 |
5 | rs1196579817 |
0.3405 | 0.703 | 0.185 | N | 0.381 | 0.275 | 0.578164481777 | gnomAD-4.0.0 | 2.56885E-06 | None | None | None | None | N | None | 1.69296E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40021E-06 | 0 | 0 |
| E/K | 33600 |
Ig-159 |
5 | None | 0.3775 | None | 0.916 | N | 0.555 | 0.189 | 0.18995819373 | gnomAD-4.0.0 | 6.92294E-07 | None | None | None | None | I | None | 0 | 0 | None | 3.90046E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| L/M | 34262 |
Ig-161 |
5 | None | 0.3151 | None | 0.999 | N | 0.613 | 0.169 | 0.484985748688 | gnomAD-4.0.0 | 6.8416E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99408E-07 | 0 | 0 |
| L/V | 34262 |
Ig-161 |
5 | None | 0.3265 | None | 0.989 | N | 0.443 | 0.164 | 0.511047945453 | gnomAD-4.0.0 | 6.8416E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99408E-07 | 0 | 0 |
| R/K | 34367 |
Ig-162 |
5 | None | 0.6577 | None | 0.997 | N | 0.506 | 0.34 | 0.368743488249 | gnomAD-4.0.0 | 1.59172E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.02371E-05 |
| R/T | 34367 |
Ig-162 |
5 | rs749757727 |
0.9776 | -0.548 | 1.0 | N | 0.704 | 0.495 | 0.675097106362 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | I | None | 0 | 0 | None | 9.97E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| L/R | 34946 |
Ig-163 |
5 | rs1185207035 |
0.8568 | None | 0.999 | N | 0.707 | 0.535 | 0.774190524746 | gnomAD-4.0.0 | 2.05242E-06 | None | None | None | None | I | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99402E-07 | 0 | 3.31268E-05 |
| T/A | 35133 |
Ig-164 |
5 | rs1391236798 |
0.2509 | None | 0.999 | N | 0.499 | 0.374 | 0.345405024496 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| T/A | 35133 |
Ig-164 |
5 | rs1391236798 |
0.2509 | None | 0.999 | N | 0.499 | 0.374 | 0.345405024496 | gnomAD-4.0.0 | 6.57117E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47054E-05 | 0 | 0 |
| T/P | 35133 |
Ig-164 |
5 | rs1391236798 |
0.6992 | -0.503 | 1.0 | N | 0.757 | 0.64 | 0.447213685739 | gnomAD-2.1.1 | 4.01E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/P | 35133 |
Ig-164 |
5 | rs1391236798 |
0.6992 | -0.503 | 1.0 | N | 0.757 | 0.64 | 0.447213685739 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/P | 35133 |
Ig-164 |
5 | rs1391236798 |
0.6992 | -0.503 | 1.0 | N | 0.757 | 0.64 | 0.447213685739 | gnomAD-4.0.0 | 3.09814E-06 | None | None | None | None | N | None | 4.00384E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.19568E-05 | 0 |
| T/A | 35424 |
Ig-166 |
5 | None | 0.0868 | None | 0.979 | N | 0.306 | 0.132 | 0.211220785272 | gnomAD-4.0.0 | 1.20034E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.31253E-06 | 0 | 0 |
| A/E | 35611 |
Ig-167 |
5 | None | 0.3902 | None | 0.22 | N | 0.588 | 0.186 | 0.443285836454 | gnomAD-4.0.0 | 6.84139E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99395E-07 | 0 | 0 |
| A/G | 35611 |
Ig-167 |
5 | None | 0.1798 | None | 0.055 | N | 0.516 | 0.145 | 0.250039746154 | gnomAD-4.0.0 | 6.84139E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99395E-07 | 0 | 0 |
| A/P | 35611 |
Ig-167 |
5 | rs1304855425 |
0.2988 | 0.355 | 0.667 | N | 0.65 | 0.236 | 0.308904156042 | gnomAD-2.1.1 | 8.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.77E-05 | 0 |
| A/P | 35611 |
Ig-167 |
5 | rs1304855425 |
0.2988 | 0.355 | 0.667 | N | 0.65 | 0.236 | 0.308904156042 | gnomAD-4.0.0 | 2.52068E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.23125E-05 | 0 | 1.46531E-04 |
| A/V | 35611 |
Ig-167 |
5 | None | 0.1773 | None | 0.124 | N | 0.516 | 0.123 | 0.374434639691 | gnomAD-4.0.0 | 6.84139E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99395E-07 | 0 | 0 |
| A/V | 35901 |
Ig-169 |
5 | None | 0.4361 | None | 1.0 | N | 0.547 | 0.342 | 0.434716162284 | gnomAD-4.0.0 | 1.6349E-06 | None | None | None | -0.986(OBSL1) -1.123(OBSCN) | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.48161E-05 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.