Structural position:
- Domain Type: Fn3
- Aligned Position: 6
- Secondary Structure Element:
- Secondary Structure Region:
SAVs
| SAV | Position (IC) | Domain | Position (Domain) | RS | AlphaMissense (IC) |
DUET |
PolyPhen-2 |
Condel |
Rhapsody |
REVEL |
MVP |
Source |
MAF |
Disease |
Zygosity |
Site annotation |
mCSM PPI |
Predicted PPI site |
Comments |
AFR |
AMR |
AMS |
ASJ |
EAS |
EUR |
FIN |
MDE |
NFE |
SAS |
OTH |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R/C | 15662 |
Fn3-1 |
6 | rs762723635 |
0.1378 | -0.574 | 1.0 | D | 0.554 | 0.286 | 0.347879110917 | gnomAD-2.1.1 | 1.08E-05 | None | None | None | None | N | None | 4.14E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.57E-05 | 0 |
| R/C | 15662 |
Fn3-1 |
6 | rs762723635 |
0.1378 | -0.574 | 1.0 | D | 0.554 | 0.286 | 0.347879110917 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 7.25E-05 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/C | 15662 |
Fn3-1 |
6 | rs762723635 |
0.1378 | -0.574 | 1.0 | D | 0.554 | 0.286 | 0.347879110917 | gnomAD-4.0.0 | 8.68395E-06 | None | None | None | None | N | None | 8.02332E-05 | 1.67146E-05 | None | 0 | 0 | None | 0 | 0 | 5.93706E-06 | 0 | 0 |
| R/H | 15662 |
Fn3-1 |
6 | rs1457971549 |
0.1329 | -1.46 | 0.998 | N | 0.451 | 0.294 | 0.387850303812 | gnomAD-2.1.1 | 4.05E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| R/H | 15662 |
Fn3-1 |
6 | rs1457971549 |
0.1329 | -1.46 | 0.998 | N | 0.451 | 0.294 | 0.387850303812 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.31251E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07125E-04 | 0 |
| R/H | 15662 |
Fn3-1 |
6 | rs1457971549 |
0.1329 | -1.46 | 0.998 | N | 0.451 | 0.294 | 0.387850303812 | gnomAD-4.0.0 | 6.2026E-06 | None | None | None | None | N | None | 0 | 3.34247E-05 | None | 0 | 4.48129E-05 | None | 1.56265E-05 | 0 | 3.39253E-06 | 1.09871E-05 | 0 |
| R/S | 15662 |
Fn3-1 |
6 | None | 0.3773 | None | 0.967 | N | 0.429 | 0.202 | 0.337135696972 | gnomAD-4.0.0 | 6.84798E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99981E-07 | 0 | 0 |
| L/V | 15763 |
Fn3-2 |
6 | None | 0.0763 | None | 0.969 | N | 0.5 | 0.163 | 0.298745278005 | gnomAD-4.0.0 | 1.59467E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86331E-06 | 0 | 0 |
| L/W | 15763 |
Fn3-2 |
6 | rs2154209220 |
0.2375 | None | 0.999 | N | 0.791 | 0.274 | 0.62360313169 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/I | 15864 |
Fn3-3 |
6 | rs1553709304 |
0.0649 | None | None | N | 0.116 | 0.039 | 0.156986980423 | gnomAD-4.0.0 | 1.65486E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.91596E-06 | 0 | 0 |
| K/E | 16060 |
Fn3-4 |
6 | rs2057387280 |
0.218 | None | 0.124 | N | 0.544 | 0.17 | 0.278143212241 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 6.07533E-05 | 0 |
| E/K | 16160 |
Fn3-5 |
6 | rs1314919427 |
0.3305 | -0.897 | 0.999 | N | 0.637 | 0.37 | 0.447803500395 | gnomAD-2.1.1 | 1.07E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 2.35E-05 | 0 |
| E/K | 16160 |
Fn3-5 |
6 | rs1314919427 |
0.3305 | -0.897 | 0.999 | N | 0.637 | 0.37 | 0.447803500395 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| E/K | 16160 |
Fn3-5 |
6 | rs1314919427 |
0.3305 | -0.897 | 0.999 | N | 0.637 | 0.37 | 0.447803500395 | gnomAD-4.0.0 | 4.96271E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.93844E-06 | 0 | 1.60339E-05 |
| T/A | 16455 |
Fn3-7 |
6 | rs374543277 |
0.1078 | -0.706 | 0.954 | N | 0.603 | 0.197 | None | gnomAD-2.1.1 | 4.72E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.4E-05 | None | 0 | 9.49E-05 | 0 |
| T/A | 16455 |
Fn3-7 |
6 | rs374543277 |
0.1078 | -0.706 | 0.954 | N | 0.603 | 0.197 | None | gnomAD-3.1.2 | 8.56E-05 | None | None | None | None | N | None | 0 | 6.57E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.61936E-04 | 2.07555E-04 | 0 |
| T/A | 16455 |
Fn3-7 |
6 | rs374543277 |
0.1078 | -0.706 | 0.954 | N | 0.603 | 0.197 | None | gnomAD-4.0.0 | 1.10704E-04 | None | None | None | None | N | None | 0 | 1.6868E-05 | None | 0 | 0 | None | 0 | 0 | 1.45298E-04 | 4.43941E-05 | 3.21781E-05 |
| T/S | 16455 |
Fn3-7 |
6 | rs1189196149 |
0.1154 | -0.775 | 0.98 | N | 0.59 | 0.178 | 0.233150807113 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
| T/S | 16455 |
Fn3-7 |
6 | rs1189196149 |
0.1154 | -0.775 | 0.98 | N | 0.59 | 0.178 | 0.233150807113 | gnomAD-4.0.0 | 1.60486E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.88032E-06 | 0 | 0 |
| G/E | 16556 |
Fn3-8 |
6 | rs866384387 |
0.6784 | -1.784 | 1.0 | N | 0.819 | 0.435 | 0.40017627803 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/E | 16556 |
Fn3-8 |
6 | rs866384387 |
0.6784 | -1.784 | 1.0 | N | 0.819 | 0.435 | 0.40017627803 | gnomAD-4.0.0 | 4.10807E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 5.79952E-05 | 1.65881E-05 |
| G/R | 16556 |
Fn3-8 |
6 | rs1193616870 |
0.7535 | -1.054 | 1.0 | D | 0.802 | 0.482 | 0.534668972696 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.63E-05 | None | 0 | None | 0 | 0 | 0 |
| G/R | 16556 |
Fn3-8 |
6 | rs1193616870 |
0.7535 | -1.054 | 1.0 | D | 0.802 | 0.482 | 0.534668972696 | gnomAD-4.0.0 | 1.59383E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86257E-06 | 0 | 0 |
| R/C | 16656 |
Fn3-9 |
6 | rs1030093239 |
0.4269 | -0.258 | 0.252 | D | 0.517 | 0.268 | 0.514866526686 | gnomAD-2.1.1 | 7.35E-06 | None | None | None | None | N | None | 4.21E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.13E-06 | 0 |
| R/C | 16656 |
Fn3-9 |
6 | rs1030093239 |
0.4269 | -0.258 | 0.252 | D | 0.517 | 0.268 | 0.514866526686 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 2.0816E-04 | 0 |
| R/C | 16656 |
Fn3-9 |
6 | rs1030093239 |
0.4269 | -0.258 | 0.252 | D | 0.517 | 0.268 | 0.514866526686 | gnomAD-4.0.0 | 1.11796E-05 | None | None | None | None | N | None | 1.33976E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.01805E-05 | 4.42165E-05 | 1.60539E-05 |
| R/H | 16656 |
Fn3-9 |
6 | rs373799076 |
0.2806 | -1.201 | 1.0 | D | 0.647 | 0.382 | None | gnomAD-2.1.1 | 3.32E-05 | None | None | None | None | N | None | 0 | 2.95E-05 | None | 0 | 2.85812E-04 | None | 0 | None | 0 | 1.86E-05 | 0 |
| R/H | 16656 |
Fn3-9 |
6 | rs373799076 |
0.2806 | -1.201 | 1.0 | D | 0.647 | 0.382 | None | gnomAD-3.1.2 | 6.61E-06 | None | None | None | None | N | None | 2.43E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/H | 16656 |
Fn3-9 |
6 | rs373799076 |
0.2806 | -1.201 | 1.0 | D | 0.647 | 0.382 | None | gnomAD-4.0.0 | 3.04448E-05 | None | None | None | None | N | None | 2.68039E-05 | 3.35762E-05 | None | 0 | 4.49762E-05 | None | 0 | 0 | 3.47887E-05 | 1.10735E-05 | 1.60498E-05 |
| R/L | 16656 |
Fn3-9 |
6 | rs373799076 |
0.5086 | None | 0.913 | N | 0.707 | 0.306 | 0.552656131934 | gnomAD-4.0.0 | 6.17284E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.10304E-06 | 0 | 0 |
| R/S | 16656 |
Fn3-9 |
6 | rs1030093239 |
0.7893 | -0.465 | 0.954 | N | 0.719 | 0.332 | 0.394536629495 | gnomAD-2.1.1 | 8.3E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.71E-05 | None | 0 | 0 | 0 |
| R/S | 16656 |
Fn3-9 |
6 | rs1030093239 |
0.7893 | -0.465 | 0.954 | N | 0.719 | 0.332 | 0.394536629495 | gnomAD-4.0.0 | 5.48543E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.80046E-06 | 5.83703E-05 | 1.66091E-05 |
| K/E | 17052 |
Fn3-12 |
6 | rs1451084974 |
0.3012 | None | 0.124 | N | 0.549 | 0.136 | 0.250579442822 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 9.5511E-04 |
| K/E | 17052 |
Fn3-12 |
6 | rs1451084974 |
0.3012 | None | 0.124 | N | 0.549 | 0.136 | 0.250579442822 | gnomAD-4.0.0 | 1.31536E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 9.5511E-04 |
| V/A | 17152 |
Fn3-13 |
6 | None | 0.2711 | None | 0.645 | N | 0.582 | 0.179 | 0.318540980066 | gnomAD-4.0.0 | 1.59519E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86421E-06 | 0 | 0 |
| V/I | 17152 |
Fn3-13 |
6 | rs1553692607 |
0.077 | None | 0.006 | N | 0.277 | 0.05 | 0.146414634003 | gnomAD-4.0.0 | 2.05508E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.05382E-05 | None | 0 | 0 | 9.001E-07 | 0 | 0 |
| D/E | 17475 |
Fn3-15 |
6 | rs1176767614 |
0.1301 | -0.538 | 0.003 | N | 0.097 | 0.03 | 0.223146558224 | gnomAD-2.1.1 | 4.35E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 1.77936E-04 |
| D/E | 17475 |
Fn3-15 |
6 | rs1176767614 |
0.1301 | -0.538 | 0.003 | N | 0.097 | 0.03 | 0.223146558224 | gnomAD-4.0.0 | 1.62648E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.07409E-05 |
| P/A | 17574 |
Fn3-16 |
6 | rs759901950 |
0.7242 | -2.137 | 1.0 | N | 0.825 | 0.351 | 0.438593652726 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
| P/S | 17574 |
Fn3-16 |
6 | rs759901950 |
0.9496 | -2.878 | 1.0 | N | 0.835 | 0.372 | 0.444202592202 | gnomAD-2.1.1 | 8.12E-06 | None | None | None | None | N | None | 6.49E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9E-06 | 0 |
| P/S | 17574 |
Fn3-16 |
6 | rs759901950 |
0.9496 | -2.878 | 1.0 | N | 0.835 | 0.372 | 0.444202592202 | gnomAD-4.0.0 | 3.18914E-06 | None | None | None | None | N | None | 5.67344E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86308E-06 | 0 | 0 |
| L/V | 17769 |
Fn3-17 |
6 | rs759317677 |
0.086 | -1.504 | 0.001 | N | 0.224 | 0.052 | 0.17948927462 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.63773E-04 | None | 0 | 0 | 0 |
| L/V | 17769 |
Fn3-17 |
6 | rs759317677 |
0.086 | -1.504 | 0.001 | N | 0.224 | 0.052 | 0.17948927462 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07297E-04 | 0 |
| L/V | 17769 |
Fn3-17 |
6 | rs759317677 |
0.086 | -1.504 | 0.001 | N | 0.224 | 0.052 | 0.17948927462 | gnomAD-4.0.0 | 1.30233E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.08819E-04 | 3.20636E-05 |
| G/R | 18171 |
Fn3-20 |
6 | rs751216891 |
0.3919 | -1.01 | 0.964 | N | 0.773 | 0.209 | 0.494232246516 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.92E-06 | 0 |
| G/R | 18171 |
Fn3-20 |
6 | rs751216891 |
0.3919 | -1.01 | 0.964 | N | 0.773 | 0.209 | 0.494232246516 | gnomAD-4.0.0 | 3.42444E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 4.50055E-06 | 0 | 0 |
| I/V | 18584 |
Fn3-23 |
6 | rs760979964 |
0.0727 | -0.922 | 0.267 | N | 0.272 | 0.195 | 0.259272394797 | gnomAD-2.1.1 | 5.29E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 6.42E-05 | None | 0 | None | 0 | 0 | 0 |
| I/V | 18584 |
Fn3-23 |
6 | rs760979964 |
0.0727 | -0.922 | 0.267 | N | 0.272 | 0.195 | 0.259272394797 | gnomAD-4.0.0 | 5.03976E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.13294E-05 | None | 0 | 0 | 4.62974E-06 | 0 | 0 |
| V/A | 18789 |
Fn3-24 |
6 | rs377635048 |
0.0867 | -1.595 | 0.565 | N | 0.615 | 0.07 | None | gnomAD-2.1.1 | 8.85E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.85E-05 | 0 |
| V/A | 18789 |
Fn3-24 |
6 | rs377635048 |
0.0867 | -1.595 | 0.565 | N | 0.615 | 0.07 | None | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 7.36E-05 | 0 | 0 |
| V/A | 18789 |
Fn3-24 |
6 | rs377635048 |
0.0867 | -1.595 | 0.565 | N | 0.615 | 0.07 | None | gnomAD-4.0.0 | 8.40602E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.13104E-05 | 0 | 0 |
| V/G | 18789 |
Fn3-24 |
6 | None | 0.1456 | None | 0.901 | N | 0.735 | 0.222 | 0.520963378925 | gnomAD-4.0.0 | 7.17141E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.24712E-07 | 0 | 0 |
| V/M | 18789 |
Fn3-24 |
6 | None | 0.1205 | None | 0.901 | N | 0.622 | 0.178 | 0.27855597813 | gnomAD-4.0.0 | 7.17812E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.83554E-04 | 0 | 0 | 0 |
| G/R | 19188 |
Fn3-27 |
6 | None | 0.3312 | None | 0.413 | N | 0.365 | 0.242 | 0.393623145366 | gnomAD-4.0.0 | 6.89016E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.03271E-07 | 0 | 0 |
| G/V | 19188 |
Fn3-27 |
6 | None | 0.2861 | None | 0.993 | N | 0.788 | 0.447 | 0.522129480193 | gnomAD-4.0.0 | 1.61777E-06 | None | None | None | None | N | None | 0 | 2.36619E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/A | 19289 |
Fn3-28 |
6 | None | 0.3952 | None | 0.999 | N | 0.682 | 0.363 | 0.59128977468 | gnomAD-4.0.0 | 1.6007E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.87581E-06 | 0 | 0 |
| E/K | 19289 |
Fn3-28 |
6 | rs1031046164 |
0.4668 | None | 0.999 | D | 0.573 | 0.385 | 0.573099714865 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 19289 |
Fn3-28 |
6 | rs1031046164 |
0.4668 | None | 0.999 | D | 0.573 | 0.385 | 0.573099714865 | gnomAD-4.0.0 | 6.57652E-06 | None | None | None | None | N | None | 2.41359E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/H | 19584 |
Fn3-30 |
6 | rs765734391 |
0.2697 | -0.651 | 0.484 | N | 0.56 | 0.193 | 0.323615622048 | gnomAD-4.0.0 | 1.59858E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86275E-06 | 0 | 0 |
| D/Y | 19584 |
Fn3-30 |
6 | rs765734391 |
0.2364 | -0.059 | 0.741 | N | 0.605 | 0.213 | 0.317378411342 | gnomAD-2.1.1 | 8.13E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 6.77E-05 | None | 0 | 0 | 0 |
| D/Y | 19584 |
Fn3-30 |
6 | rs765734391 |
0.2364 | -0.059 | 0.741 | N | 0.605 | 0.213 | 0.317378411342 | gnomAD-4.0.0 | 3.19718E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.918E-05 | 0 |
| R/T | 19882 |
Fn3-32 |
6 | rs1309373929 |
0.1518 | -0.247 | 0.98 | N | 0.548 | 0.295 | 0.418344901717 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.1E-06 | 0 |
| R/T | 19882 |
Fn3-32 |
6 | rs1309373929 |
0.1518 | -0.247 | 0.98 | N | 0.548 | 0.295 | 0.418344901717 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 19882 |
Fn3-32 |
6 | rs1309373929 |
0.1518 | -0.247 | 0.98 | N | 0.548 | 0.295 | 0.418344901717 | gnomAD-4.0.0 | 2.56972E-06 | None | None | None | None | N | None | 1.69405E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.39771E-06 | 0 | 0 |
| T/A | 20176 |
Fn3-34 |
6 | None | 0.0783 | None | 0.826 | N | 0.437 | 0.124 | 0.181679512989 | gnomAD-4.0.0 | 1.59199E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85969E-06 | 0 | 0 |
| I/T | 20376 |
Fn3-36 |
6 | rs1366424798 |
0.4357 | -1.759 | 0.978 | N | 0.69 | 0.348 | 0.370608029945 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| I/T | 20376 |
Fn3-36 |
6 | rs1366424798 |
0.4357 | -1.759 | 0.978 | N | 0.69 | 0.348 | 0.370608029945 | gnomAD-4.0.0 | 7.96813E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 7.1804E-05 | 0 |
| I/V | 20376 |
Fn3-36 |
6 | None | 0.0808 | None | 0.198 | N | 0.203 | 0.123 | 0.21279746466 | gnomAD-4.0.0 | 1.5936E-06 | None | None | None | None | N | None | 0 | 2.29106E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| Q/R | 20574 |
Fn3-37 |
6 | rs1176666570 |
0.1239 | -0.435 | 0.99 | N | 0.589 | 0.327 | 0.227934060464 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.91E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/A | 20673 |
Fn3-38 |
6 | rs2049807287 |
0.6691 | None | 0.999 | N | 0.751 | 0.307 | 0.475034548194 | gnomAD-4.0.0 | 1.59178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85943E-06 | 0 | 0 |
| E/K | 20673 |
Fn3-38 |
6 | rs2049807795 |
0.6793 | None | 0.999 | N | 0.654 | 0.344 | 0.46289702323 | gnomAD-4.0.0 | 1.36862E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 1.73732E-04 | 8.99586E-07 | 0 | 0 |
| T/A | 21069 |
Fn3-41 |
6 | None | 0.0732 | None | 0.061 | N | 0.125 | 0.114 | 0.110078149338 | gnomAD-4.0.0 | 7.00326E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 1.70016E-05 |
| R/G | 21371 |
Fn3-43 |
6 | rs748901968 |
0.5913 | None | 0.549 | N | 0.577 | 0.221 | 0.498323335527 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 2.94E-05 | 0 | 0 |
| R/G | 21371 |
Fn3-43 |
6 | rs748901968 |
0.5913 | None | 0.549 | N | 0.577 | 0.221 | 0.498323335527 | gnomAD-4.0.0 | 1.30258E-05 | None | None | None | None | N | None | 0 | 1.67246E-05 | None | 0 | 0 | None | 0 | 0 | 1.52657E-05 | 0 | 3.20554E-05 |
| R/S | 21371 |
Fn3-43 |
6 | rs2049074403 |
0.8482 | None | 0.379 | N | 0.557 | 0.18 | 0.286465849087 | gnomAD-4.0.0 | 1.59492E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43997E-05 | 0 |
| R/T | 21371 |
Fn3-43 |
6 | None | 0.6945 | None | 0.549 | N | 0.586 | 0.217 | 0.409398589964 | gnomAD-4.0.0 | 1.59501E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.86339E-06 | 0 | 0 |
| Q/L | 21564 |
Fn3-44 |
6 | None | 0.1588 | None | 0.801 | N | 0.468 | 0.193 | 0.323886383625 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| K/R | 21664 |
Fn3-45 |
6 | rs376637538 |
0.0758 | None | 0.003 | N | 0.235 | 0.094 | None | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| K/R | 21664 |
Fn3-45 |
6 | rs376637538 |
0.0758 | None | 0.003 | N | 0.235 | 0.094 | None | gnomAD-4.0.0 | 6.57436E-06 | None | None | None | None | N | None | 2.41324E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 21762 |
Fn3-46 |
6 | rs772939753 |
0.8037 | -0.957 | 1.0 | N | 0.821 | 0.431 | 0.624040304256 | gnomAD-2.1.1 | 1.93E-05 | None | None | None | None | N | None | 0 | 1.36064E-04 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 21961 |
Fn3-47 |
6 | rs778340197 |
0.1134 | -1.07 | 0.892 | N | 0.593 | 0.176 | 0.224531998449 | gnomAD-2.1.1 | 4.09E-06 | None | None | None | None | N | None | 0 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| A/T | 21961 |
Fn3-47 |
6 | rs778340197 |
0.1134 | -1.07 | 0.892 | N | 0.593 | 0.176 | 0.224531998449 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 21961 |
Fn3-47 |
6 | rs778340197 |
0.1134 | -1.07 | 0.892 | N | 0.593 | 0.176 | 0.224531998449 | gnomAD-4.0.0 | 6.57756E-06 | None | None | None | None | N | None | 0 | 6.55566E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/G | 22060 |
Fn3-48 |
6 | rs777203619 |
0.3285 | None | 0.989 | N | 0.591 | 0.447 | None | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| D/G | 22060 |
Fn3-48 |
6 | rs777203619 |
0.3285 | None | 0.989 | N | 0.591 | 0.447 | None | gnomAD-4.0.0 | 1.7985E-05 | None | None | None | None | N | None | 1.33654E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.37413E-05 | 0 | 0 |
| D/Y | 22060 |
Fn3-48 |
6 | rs1201131904 |
0.3969 | None | 1.0 | N | 0.747 | 0.418 | 0.498767733754 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/Y | 22060 |
Fn3-48 |
6 | rs1201131904 |
0.3969 | None | 1.0 | N | 0.747 | 0.418 | 0.498767733754 | gnomAD-4.0.0 | 6.57877E-06 | None | None | None | None | N | None | 0 | 6.56254E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/T | 22161 |
Fn3-49 |
6 | rs886038883 |
0.2081 | None | 0.056 | N | 0.273 | 0.184 | 0.115124310173 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 22359 |
Fn3-50 |
6 | rs2303838 |
0.0813 | -0.544 | 0.003 | N | 0.171 | 0.029 | None | gnomAD-2.1.1 | 2.40208E-01 | None | None | None | None | N | None | 3.3412E-01 | 1.92856E-01 | None | 2.35072E-01 | 6.10084E-01 | None | 3.26264E-01 | None | 1.71405E-01 | 1.74205E-01 | 2.1685E-01 |
| V/I | 22359 |
Fn3-50 |
6 | rs2303838 |
0.0813 | -0.544 | 0.003 | N | 0.171 | 0.029 | None | gnomAD-3.1.2 | 2.45014E-01 | None | None | None | None | N | None | 3.35173E-01 | 2.00052E-01 | 4.85619E-01 | 2.36736E-01 | 6.13512E-01 | None | 1.81913E-01 | 2.05696E-01 | 1.74161E-01 | 3.28002E-01 | 2.33014E-01 |
| V/I | 22359 |
Fn3-50 |
6 | rs2303838 |
0.0813 | -0.544 | 0.003 | N | 0.171 | 0.029 | None | 1000 genomes | 3.51238E-01 | None | None | None | None | N | None | 3.434E-01 | 2.147E-01 | None | None | 6.31E-01 | 1.849E-01 | None | None | None | 3.415E-01 | None |
| V/I | 22359 |
Fn3-50 |
6 | rs2303838 |
0.0813 | -0.544 | 0.003 | N | 0.171 | 0.029 | None | gnomAD-4.0.0 | 2.02234E-01 | None | None | None | None | N | None | 3.36518E-01 | 1.97103E-01 | None | 2.36169E-01 | 6.14035E-01 | None | 1.71923E-01 | 2.5091E-01 | 1.68169E-01 | 3.23843E-01 | 2.24165E-01 |
| V/M | 22456 |
Fn3-51 |
6 | rs2047288544 |
0.1243 | None | 0.934 | N | 0.477 | 0.125 | 0.309839678437 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 0 | 1.96696E-04 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/M | 22456 |
Fn3-51 |
6 | rs2047288544 |
0.1243 | None | 0.934 | N | 0.477 | 0.125 | 0.309839678437 | gnomAD-4.0.0 | 1.97275E-05 | None | None | None | None | N | None | 0 | 1.96696E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| T/N | 22648 |
Fn3-52 |
6 | None | 0.1564 | None | 0.998 | N | 0.692 | 0.233 | 0.283761946502 | gnomAD-4.0.0 | 1.71096E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.24906E-05 | 0 | 0 |
| P/L | 22748 |
Fn3-53 |
6 | rs780062324 |
0.0887 | -0.81 | 0.961 | N | 0.606 | 0.318 | 0.491044626064 | gnomAD-2.1.1 | 1.63E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 3.59E-05 | 0 |
| P/L | 22748 |
Fn3-53 |
6 | rs780062324 |
0.0887 | -0.81 | 0.961 | N | 0.606 | 0.318 | 0.491044626064 | gnomAD-4.0.0 | 2.12469E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.87448E-05 | 0 | 2.61045E-05 | 1.16978E-05 | 0 |
| P/R | 22748 |
Fn3-53 |
6 | None | 0.2287 | None | 0.994 | N | 0.635 | 0.358 | 0.375326005269 | gnomAD-4.0.0 | 6.85384E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00155E-07 | 0 | 0 |
| G/A | 22846 |
Fn3-54 |
6 | rs757698964 |
0.4444 | -0.414 | 1.0 | N | 0.616 | 0.457 | None | gnomAD-2.1.1 | 4.5E-06 | None | None | None | None | N | None | 6.64E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/A | 22846 |
Fn3-54 |
6 | rs757698964 |
0.4444 | -0.414 | 1.0 | N | 0.616 | 0.457 | None | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 22846 |
Fn3-54 |
6 | rs757698964 |
0.4444 | -0.414 | 1.0 | N | 0.616 | 0.457 | None | gnomAD-4.0.0 | 6.57575E-06 | None | None | None | None | N | None | 2.41266E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 23045 |
Fn3-55 |
6 | rs762347167 |
0.2699 | -0.912 | 1.0 | N | 0.747 | 0.381 | 0.307016933798 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/S | 23045 |
Fn3-55 |
6 | rs762347167 |
0.2699 | -0.912 | 1.0 | N | 0.747 | 0.381 | 0.307016933798 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.42E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 23045 |
Fn3-55 |
6 | rs762347167 |
0.2699 | -0.912 | 1.0 | N | 0.747 | 0.381 | 0.307016933798 | gnomAD-4.0.0 | 2.56508E-06 | None | None | None | None | N | None | 3.38776E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| D/V | 23537 |
Fn3-59 |
6 | rs1193472633 |
0.1657 | 0.213 | 0.638 | N | 0.759 | 0.288 | 0.504968073517 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| T/S | 23731 |
Fn3-60 |
6 | None | 0.1075 | None | 0.549 | N | 0.543 | 0.13 | 0.156986980423 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| G/C | 23831 |
Fn3-61 |
6 | rs1200630554 |
0.4431 | -0.456 | 1.0 | D | 0.769 | 0.567 | 0.757097561137 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| G/C | 23831 |
Fn3-61 |
6 | rs1200630554 |
0.4431 | -0.456 | 1.0 | D | 0.769 | 0.567 | 0.757097561137 | gnomAD-4.0.0 | 6.84588E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.9979E-07 | 0 | 0 |
| G/V | 23831 |
Fn3-61 |
6 | rs746618179 |
0.6178 | 0.108 | 1.0 | N | 0.803 | 0.549 | 0.751024834577 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| G/V | 23831 |
Fn3-61 |
6 | rs746618179 |
0.6178 | 0.108 | 1.0 | N | 0.803 | 0.549 | 0.751024834577 | gnomAD-4.0.0 | 4.78022E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.72354E-06 | 0 | 3.02755E-05 |
| G/R | 23929 |
Fn3-62 |
6 | rs969302991 |
0.5338 | -0.924 | 1.0 | N | 0.836 | 0.475 | 0.620070164782 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 4.64E-05 | 8.89E-06 | 0 |
| G/R | 23929 |
Fn3-62 |
6 | rs969302991 |
0.5338 | -0.924 | 1.0 | N | 0.836 | 0.475 | 0.620070164782 | gnomAD-3.1.2 | 2.63E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 5.88E-05 | 0 | 0 |
| G/R | 23929 |
Fn3-62 |
6 | rs969302991 |
0.5338 | -0.924 | 1.0 | N | 0.836 | 0.475 | 0.620070164782 | gnomAD-4.0.0 | 3.03713E-05 | None | None | None | None | N | None | 0 | 5.003E-05 | None | 0 | 0 | None | 3.12539E-05 | 0 | 3.72991E-05 | 0 | 0 |
| E/K | 24127 |
Fn3-63 |
6 | rs149763294 |
0.1086 | -0.979 | 0.999 | N | 0.632 | 0.311 | None | gnomAD-2.1.1 | 4.89425E-04 | None | None | None | None | N | None | 1.8046E-03 | 9.08147E-04 | None | 1.564E-03 | 0 | None | 0 | None | 4.22E-05 | 2.93526E-04 | 7.75675E-04 |
| E/K | 24127 |
Fn3-63 |
6 | rs149763294 |
0.1086 | -0.979 | 0.999 | N | 0.632 | 0.311 | None | gnomAD-3.1.2 | 8.2849E-04 | None | None | None | None | N | None | 1.8826E-03 | 1.31044E-03 | 0 | 1.72911E-03 | 0 | None | 0 | 0 | 3.08878E-04 | 0 | 4.78469E-04 |
| E/K | 24127 |
Fn3-63 |
6 | rs149763294 |
0.1086 | -0.979 | 0.999 | N | 0.632 | 0.311 | None | 1000 genomes | 9.98403E-04 | None | None | None | None | N | None | 1.5E-03 | 2.9E-03 | None | None | 0 | 1E-03 | None | None | None | 0 | None |
| E/K | 24127 |
Fn3-63 |
6 | rs149763294 |
0.1086 | -0.979 | 0.999 | N | 0.632 | 0.311 | None | gnomAD-4.0.0 | 2.84901E-04 | None | None | None | None | N | None | 1.80633E-03 | 9.49078E-04 | None | 1.47726E-03 | 0 | None | 0 | 1.19007E-03 | 1.56915E-04 | 0 | 5.72625E-04 |
| K/Q | 24227 |
Fn3-64 |
6 | rs1333523637 |
0.1038 | -0.396 | 0.016 | N | 0.19 | 0.064 | 0.219573609325 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.49E-05 | 0 |
| K/Q | 24227 |
Fn3-64 |
6 | rs1333523637 |
0.1038 | -0.396 | 0.016 | N | 0.19 | 0.064 | 0.219573609325 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| K/Q | 24227 |
Fn3-64 |
6 | rs1333523637 |
0.1038 | -0.396 | 0.016 | N | 0.19 | 0.064 | 0.219573609325 | gnomAD-4.0.0 | 2.92786E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.35272E-06 | 0 | 0 |
| Q/E | 24524 |
Fn3-66 |
6 | None | 0.1226 | None | 0.979 | N | 0.554 | 0.224 | 0.341460817117 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| Q/K | 24524 |
Fn3-66 |
6 | rs753429609 |
0.0888 | None | 0.991 | N | 0.596 | 0.316 | 0.353125101423 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 6.17284E-04 | 0 | 0 | 0 |
| G/R | 24621 |
Fn3-67 |
6 | rs776476061 |
0.5588 | -1.114 | 1.0 | N | 0.784 | 0.336 | 0.5732715451 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/R | 24621 |
Fn3-67 |
6 | rs776476061 |
0.5588 | -1.114 | 1.0 | N | 0.784 | 0.336 | 0.5732715451 |
Huang (2021)
| None |
Other
|
comp het with Y4418* | None | None | N | Genetic analysis of NMD patients; variant prioritisation; no validation | None | None | None | None | None | None | None | None | None | None | None |
| G/R | 24621 |
Fn3-67 |
6 | rs776476061 |
0.5588 | -1.114 | 1.0 | N | 0.784 | 0.336 | 0.5732715451 | gnomAD-4.0.0 | 7.5294E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52666E-05 | None | 0 | 0 | 0 | 1.04408E-04 | 1.65739E-05 |
| T/A | 24813 |
Fn3-68 |
6 | rs750126076 |
0.0815 | -0.695 | 0.004 | N | 0.29 | 0.087 | 0.143124449307 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| T/A | 24813 |
Fn3-68 |
6 | rs750126076 |
0.0815 | -0.695 | 0.004 | N | 0.29 | 0.087 | 0.143124449307 | gnomAD-4.0.0 | 3.42161E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.8735E-05 | 0 | 0 | 4.63779E-05 | 0 |
| T/I | 24813 |
Fn3-68 |
6 | None | 0.1194 | None | 0.81 | N | 0.63 | 0.167 | 0.24896430686 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/N | 24813 |
Fn3-68 |
6 | rs1559405404 |
0.1383 | None | 0.549 | N | 0.563 | 0.124 | 0.20549828249 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| T/P | 24813 |
Fn3-68 |
6 | rs750126076 |
0.4454 | -0.16 | 0.896 | N | 0.629 | 0.233 | 0.263612267334 | gnomAD-2.1.1 | 8.07E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 1.79E-05 | 0 |
| T/P | 24813 |
Fn3-68 |
6 | rs750126076 |
0.4454 | -0.16 | 0.896 | N | 0.629 | 0.233 | 0.263612267334 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 9.41E-05 | 0 | 0 | 0 | 0 |
| T/P | 24813 |
Fn3-68 |
6 | rs750126076 |
0.4454 | -0.16 | 0.896 | N | 0.629 | 0.233 | 0.263612267334 | gnomAD-4.0.0 | 9.91699E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.56245E-05 | 0 | 1.27161E-05 | 0 | 0 |
| G/A | 25011 |
Fn3-70 |
6 | None | 0.3794 | None | 1.0 | N | 0.647 | 0.387 | 0.374255764437 | gnomAD-4.0.0 | 1.59192E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43303E-05 | 0 |
| G/E | 25011 |
Fn3-70 |
6 | rs1267255162 |
0.6354 | -1.867 | 1.0 | N | 0.871 | 0.448 | 0.542007956216 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.97E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/E | 25011 |
Fn3-70 |
6 | rs1267255162 |
0.6354 | -1.867 | 1.0 | N | 0.871 | 0.448 | 0.542007956216 | gnomAD-4.0.0 | 3.18384E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.53652E-05 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 25011 |
Fn3-70 |
6 | rs1448093257 |
0.7878 | -1.087 | 1.0 | N | 0.858 | 0.489 | 0.686066944425 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/R | 25011 |
Fn3-70 |
6 | rs1448093257 |
0.7878 | -1.087 | 1.0 | N | 0.858 | 0.489 | 0.686066944425 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 25011 |
Fn3-70 |
6 | rs1448093257 |
0.7878 | -1.087 | 1.0 | N | 0.858 | 0.489 | 0.686066944425 | gnomAD-4.0.0 | 6.57505E-06 | None | None | None | None | N | None | 2.41266E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| E/K | 25209 |
Fn3-71 |
6 | rs773767237 |
0.1851 | -0.765 | 0.008 | N | 0.405 | 0.127 | 0.176091768786 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 5.81E-05 | None | 9.97E-05 | 0 | None | 0 | None | 0 | 0 | 0 |
| E/K | 25209 |
Fn3-71 |
6 | rs773767237 |
0.1851 | -0.765 | 0.008 | N | 0.405 | 0.127 | 0.176091768786 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| E/K | 25209 |
Fn3-71 |
6 | rs773767237 |
0.1851 | -0.765 | 0.008 | N | 0.405 | 0.127 | 0.176091768786 | gnomAD-4.0.0 | 1.15378E-05 | None | None | None | None | N | None | 0 | 1.01778E-04 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 8.53922E-05 |
| N/D | 25410 |
Fn3-73 |
6 | rs749561648 |
0.309 | -0.545 | 0.981 | N | 0.509 | 0.211 | 0.36893422563 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.91E-06 | 0 |
| N/D | 25410 |
Fn3-73 |
6 | rs749561648 |
0.309 | -0.545 | 0.981 | N | 0.509 | 0.211 | 0.36893422563 | gnomAD-4.0.0 | 1.16341E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.52929E-05 | 0 | 0 |
| N/I | 25410 |
Fn3-73 |
6 | rs397517706 |
0.1386 | 0.353 | 0.056 | N | 0.559 | 0.246 | 0.592484638094 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| N/I | 25410 |
Fn3-73 |
6 | rs397517706 |
0.1386 | 0.353 | 0.056 | N | 0.559 | 0.246 | 0.592484638094 | gnomAD-4.0.0 | 4.77622E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.29984E-05 | 0 |
| N/K | 25410 |
Fn3-73 |
6 | None | 0.4466 | None | 0.983 | N | 0.661 | 0.258 | 0.263140351381 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| V/A | 25606 |
Fn3-74 |
6 | rs1343757002 |
0.1131 | None | None | N | 0.082 | 0.059 | 0.208000267992 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/A | 25606 |
Fn3-74 |
6 | rs1343757002 |
0.1131 | None | None | N | 0.082 | 0.059 | 0.208000267992 | gnomAD-4.0.0 | 1.31465E-05 | None | None | None | None | N | None | 4.82509E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 25606 |
Fn3-74 |
6 | rs794729501 |
0.0699 | -0.745 | None | N | 0.121 | 0.051 | 0.234412748748 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 6.47E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/I | 25606 |
Fn3-74 |
6 | rs794729501 |
0.0699 | -0.745 | None | N | 0.121 | 0.051 | 0.234412748748 | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 25606 |
Fn3-74 |
6 | rs794729501 |
0.0699 | -0.745 | None | N | 0.121 | 0.051 | 0.234412748748 | gnomAD-4.0.0 | 7.44128E-06 | None | None | None | None | N | None | 1.06852E-04 | 1.6695E-05 | None | 0 | 2.22936E-05 | None | 0 | 0 | 1.69604E-06 | 0 | 0 |
| V/L | 25606 |
Fn3-74 |
6 | rs794729501 |
0.1025 | -0.749 | 0.002 | N | 0.313 | 0.04 | 0.110078149338 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.29E-05 | None | 0 | 0 | 0 |
| V/L | 25606 |
Fn3-74 |
6 | rs794729501 |
0.1025 | -0.749 | 0.002 | N | 0.313 | 0.04 | 0.110078149338 | gnomAD-4.0.0 | 6.84686E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.16239E-05 | 0 |
| G/R | 25703 |
Fn3-75 |
6 | None | 0.6271 | None | 0.931 | N | 0.688 | 0.169 | 0.445007932271 | gnomAD-4.0.0 | 1.36884E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.79928E-06 | 0 | 0 |
| K/E | 25895 |
Fn3-76 |
6 | rs1706799678 |
0.0959 | None | 0.042 | N | 0.405 | 0.055 | 0.166414681773 | gnomAD-4.0.0 | 1.59231E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85969E-06 | 0 | 0 |
| K/T | 25895 |
Fn3-76 |
6 | rs751395038 |
0.0719 | -1.207 | None | N | 0.293 | 0.078 | 0.171388866994 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| K/T | 25895 |
Fn3-76 |
6 | rs751395038 |
0.0719 | -1.207 | None | N | 0.293 | 0.078 | 0.171388866994 | gnomAD-4.0.0 | 3.18459E-06 | None | None | None | None | N | None | 0 | 2.28822E-05 | None | 0 | 0 | None | 0 | 0 | 2.85971E-06 | 0 | 0 |
| G/C | 25995 |
Fn3-77 |
6 | None | 0.7131 | None | 1.0 | D | 0.814 | 0.443 | 0.748405412012 | gnomAD-4.0.0 | 1.59181E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85935E-06 | 0 | 0 |
| G/D | 25995 |
Fn3-77 |
6 | rs745801476 |
0.9313 | -1.267 | 0.45 | N | 0.529 | 0.292 | 0.230578612272 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| G/D | 25995 |
Fn3-77 |
6 | rs745801476 |
0.9313 | -1.267 | 0.45 | N | 0.529 | 0.292 | 0.230578612272 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/D | 25995 |
Fn3-77 |
6 | rs745801476 |
0.9313 | -1.267 | 0.45 | N | 0.529 | 0.292 | 0.230578612272 | gnomAD-4.0.0 | 6.57877E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.47132E-05 | 0 | 0 |
| G/S | 25995 |
Fn3-77 |
6 | None | 0.2435 | None | 0.997 | N | 0.693 | 0.327 | 0.233150807113 | gnomAD-4.0.0 | 1.59181E-06 | None | None | None | None | N | None | 0 | 2.28676E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/V | 25995 |
Fn3-77 |
6 | rs745801476 |
0.8512 | 0.01 | 0.999 | N | 0.829 | 0.458 | 0.653206263661 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| G/V | 25995 |
Fn3-77 |
6 | rs745801476 |
0.8512 | 0.01 | 0.999 | N | 0.829 | 0.458 | 0.653206263661 | gnomAD-4.0.0 | 1.36863E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99575E-07 | 1.15939E-05 | 0 |
| G/R | 26093 |
Fn3-78 |
6 | rs757813739 |
0.8547 | -0.679 | 1.0 | N | 0.795 | 0.492 | 0.491996647052 | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 9.95E-05 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| G/R | 26093 |
Fn3-78 |
6 | rs757813739 |
0.8547 | -0.679 | 1.0 | N | 0.795 | 0.492 | 0.491996647052 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/R | 26093 |
Fn3-78 |
6 | rs757813739 |
0.8547 | -0.679 | 1.0 | N | 0.795 | 0.492 | 0.491996647052 | gnomAD-4.0.0 | 6.19836E-06 | None | None | None | None | N | None | 0 | 0 | None | 3.37929E-05 | 0 | None | 0 | 0 | 7.62978E-06 | 0 | 0 |
| G/A | 26785 |
Fn3-83 |
6 | None | 0.2035 | None | 0.996 | N | 0.692 | 0.395 | 0.284539287134 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/R | 26785 |
Fn3-83 |
6 | None | 0.4549 | None | 1.0 | N | 0.89 | 0.47 | 0.445007932271 | gnomAD-4.0.0 | 4.10571E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.39745E-06 | 0 | 0 |
| V/A | 26977 |
Fn3-84 |
6 | rs774769114 |
0.0813 | -1.566 | 0.012 | N | 0.54 | 0.045 | None | gnomAD-2.1.1 | 7.15E-06 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| V/A | 26977 |
Fn3-84 |
6 | rs774769114 |
0.0813 | -1.566 | 0.012 | N | 0.54 | 0.045 | None | gnomAD-3.1.2 | 1.97E-05 | None | None | None | None | N | None | 4.83E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/A | 26977 |
Fn3-84 |
6 | rs774769114 |
0.0813 | -1.566 | 0.012 | N | 0.54 | 0.045 | None | gnomAD-4.0.0 | 3.71874E-06 | None | None | None | None | N | None | 4.00513E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 2.54307E-06 | 0 | 0 |
| V/F | 26977 |
Fn3-84 |
6 | None | 0.1753 | None | 0.295 | D | 0.619 | 0.076 | 0.424549175451 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| V/G | 26977 |
Fn3-84 |
6 | rs774769114 |
0.124 | None | 0.055 | N | 0.643 | 0.109 | 0.414539908741 | gnomAD-3.1.2 | 1.32E-05 | None | None | None | None | N | None | 0 | 6.56E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| V/G | 26977 |
Fn3-84 |
6 | rs774769114 |
0.124 | None | 0.055 | N | 0.643 | 0.109 | 0.414539908741 | gnomAD-4.0.0 | 2.47916E-06 | None | None | None | None | N | None | 0 | 1.66789E-05 | None | 0 | 0 | None | 0 | 0 | 1.69538E-06 | 0 | 1.60159E-05 |
| V/I | 26977 |
Fn3-84 |
6 | None | 0.0797 | None | 0.029 | N | 0.573 | 0.021 | 0.18995819373 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 0 |
| G/E | 27077 |
Fn3-85 |
6 | rs866460539 |
0.92 | -1.595 | 1.0 | N | 0.793 | 0.456 | 0.443592365053 | gnomAD-2.1.1 | 3.19E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 6.48E-05 | 0 |
| G/E | 27077 |
Fn3-85 |
6 | rs866460539 |
0.92 | -1.595 | 1.0 | N | 0.793 | 0.456 | 0.443592365053 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/E | 27077 |
Fn3-85 |
6 | rs866460539 |
0.92 | -1.595 | 1.0 | N | 0.793 | 0.456 | 0.443592365053 | gnomAD-4.0.0 | 2.03002E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40991E-06 | 0 | 0 |
| G/R | 27077 |
Fn3-85 |
6 | rs878898668 |
0.9206 | -1.013 | 1.0 | N | 0.779 | 0.503 | 0.617691798299 | gnomAD-2.1.1 | 1.62E-05 | None | None | None | None | N | None | 1.94099E-04 | 2.92E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/R | 27077 |
Fn3-85 |
6 | rs878898668 |
0.9206 | -1.013 | 1.0 | N | 0.779 | 0.503 | 0.617691798299 | gnomAD-3.1.2 | 3.29E-05 | None | None | None | None | N | None | 9.65E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/R | 27077 |
Fn3-85 |
6 | rs878898668 |
0.9206 | -1.013 | 1.0 | N | 0.779 | 0.503 | 0.617691798299 | gnomAD-4.0.0 | 1.41165E-05 | None | None | None | None | N | None | 1.35598E-04 | 1.69993E-05 | None | 0 | 0 | None | 0 | 0 | 4.79136E-06 | 0 | 0 |
| G/V | 27077 |
Fn3-85 |
6 | None | 0.8527 | None | 1.0 | N | 0.799 | 0.498 | 0.591405023974 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.75482E-04 | None | 0 | 0 | 0 | 0 | 0 |
| G/A | 27175 |
Fn3-86 |
6 | None | 0.4138 | None | 1.0 | N | 0.61 | 0.393 | 0.408853032482 | gnomAD-4.0.0 | 1.20032E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 3.66327E-05 |
| G/D | 27175 |
Fn3-86 |
6 | rs1704984751 |
0.7062 | None | 1.0 | N | 0.752 | 0.467 | 0.431931272081 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| G/D | 27175 |
Fn3-86 |
6 | rs1704984751 |
0.7062 | None | 1.0 | N | 0.752 | 0.467 | 0.431931272081 | gnomAD-4.0.0 | 6.57471E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 4.78927E-04 |
| G/S | 27175 |
Fn3-86 |
6 | rs749305586 |
0.2235 | -1.074 | 1.0 | N | 0.651 | 0.369 | 0.367612772649 | gnomAD-2.1.1 | 1.21E-05 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 1.78E-05 | 0 |
| G/S | 27175 |
Fn3-86 |
6 | rs749305586 |
0.2235 | -1.074 | 1.0 | N | 0.651 | 0.369 | 0.367612772649 | gnomAD-3.1.2 | 6.58E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 27175 |
Fn3-86 |
6 | rs749305586 |
0.2235 | -1.074 | 1.0 | N | 0.651 | 0.369 | 0.367612772649 | gnomAD-4.0.0 | 8.05774E-06 | None | None | None | None | N | None | 0 | 5.00367E-05 | None | 0 | 0 | None | 0 | 0 | 7.62914E-06 | 0 | 1.60159E-05 |
| S/L | 27474 |
Fn3-88 |
6 | rs781507920 |
0.1162 | None | 0.97 | N | 0.739 | 0.291 | 0.470237251169 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/G | 27575 |
Fn3-89 |
6 | rs763068189 |
0.0732 | -0.789 | 0.334 | N | 0.428 | 0.154 | 0.230578612272 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 2.9E-05 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| S/G | 27575 |
Fn3-89 |
6 | rs763068189 |
0.0732 | -0.789 | 0.334 | N | 0.428 | 0.154 | 0.230578612272 | gnomAD-4.0.0 | 3.18304E-06 | None | None | None | None | N | None | 0 | 2.28718E-05 | None | 0 | 0 | None | 0 | 0 | 2.85845E-06 | 0 | 0 |
| G/R | 27868 |
Fn3-91 |
6 | None | 0.4862 | None | 0.999 | D | 0.863 | 0.291 | 0.474722520063 | gnomAD-4.0.0 | 6.85767E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.00328E-07 | 0 | 0 |
| G/D | 28060 |
Fn3-92 |
6 | rs758626435 |
0.4435 | -1.546 | 0.822 | N | 0.757 | 0.267 | 0.320256813643 | gnomAD-2.1.1 | 7.16E-06 | None | None | None | None | N | None | 8.27E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/D | 28060 |
Fn3-92 |
6 | rs758626435 |
0.4435 | -1.546 | 0.822 | N | 0.757 | 0.267 | 0.320256813643 | gnomAD-3.1.2 | 3.94E-05 | None | None | None | None | N | None | 1.44823E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 28060 |
Fn3-92 |
6 | rs758626435 |
0.4435 | -1.546 | 0.822 | N | 0.757 | 0.267 | 0.320256813643 | gnomAD-4.0.0 | 1.02573E-05 | None | None | None | None | N | None | 1.18447E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 2.3952E-06 | 0 | 0 |
| T/A | 28555 |
Fn3-96 |
6 | None | 0.0639 | None | 0.78 | N | 0.588 | 0.156 | 0.198526703765 | gnomAD-4.0.0 | 1.59219E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.85894E-06 | 0 | 0 |
| T/K | 28555 |
Fn3-96 |
6 | None | 0.0933 | None | 0.137 | N | 0.34 | 0.155 | 0.229924730088 | gnomAD-4.0.0 | 6.8437E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99536E-07 | 0 | 0 |
| T/M | 28555 |
Fn3-96 |
6 | rs778254289 |
0.0898 | 0.019 | 1.0 | N | 0.692 | 0.279 | 0.347879110917 | gnomAD-2.1.1 | 2.02E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.61E-05 | None | 9.82E-05 | None | 0 | 8.91E-06 | 0 |
| T/M | 28555 |
Fn3-96 |
6 | rs778254289 |
0.0898 | 0.019 | 1.0 | N | 0.692 | 0.279 | 0.347879110917 | gnomAD-4.0.0 | 9.58118E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19629E-06 | 5.79912E-05 | 1.65706E-05 |
| S/F | 28656 |
Fn3-97 |
6 | rs1703122719 |
0.3522 | None | 0.939 | N | 0.631 | 0.342 | 0.638346370533 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/F | 28656 |
Fn3-97 |
6 | rs1703122719 |
0.3522 | None | 0.939 | N | 0.631 | 0.342 | 0.638346370533 | gnomAD-4.0.0 | 6.57471E-06 | None | None | None | None | N | None | 0 | 6.55308E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 28656 |
Fn3-97 |
6 | None | 0.1 | None | 0.003 | N | 0.098 | 0.036 | 0.117506650769 | gnomAD-4.0.0 | 2.05273E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69854E-06 | 0 | 0 |
| T/N | 28850 |
Fn3-98 |
6 | rs377049333 |
0.0817 | None | 0.007 | N | 0.275 | 0.105 | None | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| T/A | 29142 |
Fn3-100 |
6 | rs1196119784 |
0.0668 | None | 0.019 | N | 0.361 | 0.072 | 0.137902524267 | gnomAD-2.1.1 | 3.18E-05 | None | None | None | None | N | None | 1.14784E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| T/A | 29142 |
Fn3-100 |
6 | rs1196119784 |
0.0668 | None | 0.019 | N | 0.361 | 0.072 | 0.137902524267 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 1.92753E-04 | None | 0 | 0 | 0 | 0 | 0 |
| T/A | 29142 |
Fn3-100 |
6 | rs1196119784 |
0.0668 | None | 0.019 | N | 0.361 | 0.072 | 0.137902524267 | gnomAD-4.0.0 | 4.05955E-06 | None | None | None | None | N | None | 1.74691E-05 | 0 | None | 0 | 1.13404E-04 | None | 0 | 0 | 2.40978E-06 | 0 | 0 |
| S/T | 29242 |
Fn3-101 |
6 | rs1416855828 |
0.2913 | None | 0.999 | N | 0.557 | 0.216 | 0.225902525712 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| S/T | 29242 |
Fn3-101 |
6 | rs1416855828 |
0.2913 | None | 0.999 | N | 0.557 | 0.216 | 0.225902525712 | gnomAD-4.0.0 | 2.02983E-06 | None | None | None | None | N | None | 1.74679E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 1.20492E-06 | 0 | 0 |
| G/A | 29538 |
Fn3-103 |
6 | rs1206917206 |
0.0658 | -0.241 | 0.001 | N | 0.273 | 0.082 | 0.0846915920261 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 6.46E-05 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/C | 29538 |
Fn3-103 |
6 | None | 0.1093 | None | 0.928 | N | 0.705 | 0.194 | 0.425851741357 | gnomAD-4.0.0 | 1.59139E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.773E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 29538 |
Fn3-103 |
6 | None | 0.0758 | None | 0.001 | N | 0.446 | 0.038 | 0.0482279557977 | gnomAD-4.0.0 | 3.18279E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71615E-06 | 0 | 0 |
| G/S | 29638 |
Fn3-104 |
6 | rs1328502977 |
0.0712 | -1.022 | None | N | 0.287 | 0.059 | 0.0551355673512 | gnomAD-2.1.1 | 4.28E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.42E-06 | 0 |
| G/S | 29638 |
Fn3-104 |
6 | rs1328502977 |
0.0712 | -1.022 | None | N | 0.287 | 0.059 | 0.0551355673512 | gnomAD-4.0.0 | 1.38067E-06 | None | None | None | None | N | None | 0 | 2.35239E-05 | None | 0 | 0 | None | 0 | 0 | 9.03592E-07 | 0 | 0 |
| A/P | 29739 |
Fn3-105 |
6 | rs1700259287 |
0.5704 | None | 0.891 | N | 0.559 | 0.183 | 0.178374595973 | gnomAD-4.0.0 | 1.63036E-06 | None | None | None | None | N | None | 0 | 2.3406E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| A/S | 29739 |
Fn3-105 |
6 | None | 0.0785 | None | 0.062 | N | 0.148 | 0.072 | 0.0482279557977 | gnomAD-4.0.0 | 1.63036E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.92879E-06 | 0 | 0 |
| R/C | 30035 |
Fn3-107 |
6 | rs397517747 |
0.1854 | -0.293 | 0.999 | N | 0.603 | 0.371 | None | gnomAD-2.1.1 | 8.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 1.11607E-04 | None | 0 | None | 0 | 0 | 0 |
| R/C | 30035 |
Fn3-107 |
6 | rs397517747 |
0.1854 | -0.293 | 0.999 | N | 0.603 | 0.371 | None | gnomAD-4.0.0 | 6.84189E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.52054E-05 | None | 0 | 0 | 7.19555E-06 | 1.15934E-05 | 0 |
| R/H | 30035 |
Fn3-107 |
6 | rs199895320 |
0.1139 | -1.235 | 0.998 | N | 0.536 | 0.281 | None | gnomAD-2.1.1 | 3.57E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 7.8E-05 | 0 |
| R/H | 30035 |
Fn3-107 |
6 | rs199895320 |
0.1139 | -1.235 | 0.998 | N | 0.536 | 0.281 | None | gnomAD-3.1.2 | 9.86E-05 | None | None | None | None | N | None | 9.65E-05 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 1.32298E-04 | 2.07297E-04 | 0 |
| R/H | 30035 |
Fn3-107 |
6 | rs199895320 |
0.1139 | -1.235 | 0.998 | N | 0.536 | 0.281 | None | gnomAD-4.0.0 | 4.83313E-05 | None | None | None | None | N | None | 5.33021E-05 | 1.66656E-05 | None | 0 | 0 | None | 0 | 1.65071E-04 | 5.76358E-05 | 3.29395E-05 | 1.60031E-05 |
| K/E | 30229 |
Fn3-108 |
6 | rs1311556437 |
0.1452 | -0.223 | 0.986 | N | 0.524 | 0.201 | 0.402899589544 | gnomAD-2.1.1 | 4.04E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.93E-06 | 0 |
| K/E | 30229 |
Fn3-108 |
6 | rs1311556437 |
0.1452 | -0.223 | 0.986 | N | 0.524 | 0.201 | 0.402899589544 | gnomAD-4.0.0 | 6.15936E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 7.19672E-06 | 0 | 1.65711E-05 |
| G/R | 30329 |
Fn3-109 |
6 | rs1178018014 |
0.6095 | -1.042 | 1.0 | N | 0.907 | 0.441 | 0.60359086051 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| G/R | 30329 |
Fn3-109 |
6 | rs1178018014 |
0.6095 | -1.042 | 1.0 | N | 0.907 | 0.441 | 0.60359086051 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.3125E-06 | 0 | 7.32654E-05 |
| V/A | 30624 |
Fn3-111 |
6 | rs886055231 |
0.067 | None | 0.139 | N | 0.269 | 0.061 | 0.233785782151 | gnomAD-4.0.0 | 2.81307E-06 | None | None | None | None | N | None | 0 | 7.78291E-05 | None | 0 | 0 | None | 0 | 0 | 9.14608E-07 | 0 | 0 |
| V/I | 30624 |
Fn3-111 |
6 | rs1474057900 |
0.0775 | None | 0.425 | N | 0.315 | 0.114 | 0.227260227426 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| V/I | 30624 |
Fn3-111 |
6 | rs1474057900 |
0.0775 | None | 0.425 | N | 0.315 | 0.114 | 0.227260227426 | gnomAD-4.0.0 | 6.57151E-06 | None | None | None | None | N | None | 2.41301E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 30724 |
Fn3-112 |
6 | None | 0.3795 | None | 1.0 | N | 0.742 | 0.432 | 0.297031009988 | gnomAD-4.0.0 | 2.40064E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.625E-06 | 0 | 0 |
| G/R | 30724 |
Fn3-112 |
6 | rs370928582 |
0.4592 | -0.914 | 1.0 | N | 0.795 | 0.458 | None | gnomAD-2.1.1 | 1.82E-05 | None | None | None | None | N | None | 2.07348E-04 | 0 | None | 0 | 0 | None | 0 | None | 0 | 0 | 0 |
| G/R | 30724 |
Fn3-112 |
6 | rs370928582 |
0.4592 | -0.914 | 1.0 | N | 0.795 | 0.458 | None | gnomAD-3.1.2 | 1.18321E-04 | None | None | None | None | N | None | 4.34447E-04 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| G/R | 30724 |
Fn3-112 |
6 | rs370928582 |
0.4592 | -0.914 | 1.0 | N | 0.795 | 0.458 | None | gnomAD-4.0.0 | 1.55823E-05 | None | None | None | None | N | None | 3.08725E-04 | 0 | None | 0 | 0 | None | 0 | 0 | 1.70414E-06 | 0 | 0 |
| G/S | 30724 |
Fn3-112 |
6 | rs370928582 |
0.1249 | -1.16 | 1.0 | N | 0.669 | 0.374 | 0.234412748748 | gnomAD-2.1.1 | 4.1E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.07E-06 | 0 |
| G/S | 30724 |
Fn3-112 |
6 | rs370928582 |
0.1249 | -1.16 | 1.0 | N | 0.669 | 0.374 | 0.234412748748 | gnomAD-4.0.0 | 1.17059E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.53765E-05 | 0 | 0 |
| T/I | 30826 |
Fn3-113 |
6 | None | 0.1337 | None | 0.317 | N | 0.586 | 0.109 | 0.247322355667 | gnomAD-4.0.0 | 3.18242E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 5.71592E-06 | 0 | 0 |
| G/C | 31021 |
Fn3-114 |
6 | None | 0.2976 | None | 1.0 | N | 0.793 | 0.456 | 0.604839314244 | gnomAD-4.0.0 | 3.18222E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.54539E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/D | 31021 |
Fn3-114 |
6 | rs1283096478 |
0.7585 | -1.699 | 1.0 | N | 0.838 | 0.346 | 0.338110398507 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 5.57E-05 | None | 0 | None | 0 | 0 | 0 |
| G/D | 31021 |
Fn3-114 |
6 | rs1283096478 |
0.7585 | -1.699 | 1.0 | N | 0.838 | 0.346 | 0.338110398507 | gnomAD-4.0.0 | 1.59111E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.77285E-05 | None | 0 | 0 | 0 | 0 | 0 |
| R/G | 31118 |
Fn3-115 |
6 | rs761397221 |
0.2051 | None | 0.117 | N | 0.517 | 0.242 | 0.202949470691 | gnomAD-4.0.0 | 2.73674E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.69832E-06 | 0 | 1.65651E-05 |
| R/K | 31118 |
Fn3-115 |
6 | rs763830779 |
0.0681 | -0.139 | None | N | 0.124 | 0.07 | 0.110078149338 | gnomAD-2.1.1 | 4.03E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.27E-05 | None | 0 | 0 | 0 |
| R/K | 31118 |
Fn3-115 |
6 | rs763830779 |
0.0681 | -0.139 | None | N | 0.124 | 0.07 | 0.110078149338 | gnomAD-4.0.0 | 1.59113E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 1.43271E-05 | 0 |
| R/S | 31118 |
Fn3-115 |
6 | rs2154147269 |
0.4556 | None | 0.027 | N | 0.518 | 0.11 | 0.0716867268079 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 2.07039E-04 | 0 |
| R/S | 31118 |
Fn3-115 |
6 | rs2154147269 |
0.4556 | None | 0.027 | N | 0.518 | 0.11 | 0.0716867268079 | gnomAD-4.0.0 | 2.56178E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 2.6801E-05 | 0 |
| T/A | 31413 |
Fn3-117 |
6 | rs1361033922 |
0.0748 | -0.794 | 0.64 | N | 0.494 | 0.163 | 0.233785782151 | gnomAD-2.1.1 | 4.06E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.32E-05 | None | 0 | 0 | 0 |
| T/A | 31413 |
Fn3-117 |
6 | rs1361033922 |
0.0748 | -0.794 | 0.64 | N | 0.494 | 0.163 | 0.233785782151 | gnomAD-4.0.0 | 2.7443E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 0 | 4.65864E-05 | 0 |
| G/D | 31511 |
Fn3-118 |
6 | None | 0.7887 | None | 1.0 | N | 0.818 | 0.429 | 0.446010312102 | gnomAD-4.0.0 | 1.66789E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.80568E-05 | None | 0 | 0 | 0 | 0 | 0 |
| G/S | 31812 |
Fn3-120 |
6 | rs754416007 |
0.1473 | -1.28 | 1.0 | N | 0.665 | 0.328 | 0.310458034454 | gnomAD-2.1.1 | 1.61E-05 | None | None | None | None | N | None | 6.46E-05 | 5.8E-05 | None | 0 | 0 | None | 0 | None | 0 | 8.89E-06 | 0 |
| G/S | 31812 |
Fn3-120 |
6 | rs754416007 |
0.1473 | -1.28 | 1.0 | N | 0.665 | 0.328 | 0.310458034454 | gnomAD-4.0.0 | 1.64306E-05 | None | None | None | None | N | None | 5.98444E-05 | 4.47868E-05 | None | 0 | 0 | None | 0 | 0 | 1.61992E-05 | 1.16001E-05 | 1.65744E-05 |
| T/I | 32404 |
Fn3-124 |
6 | rs752957686 |
0.1017 | 0.243 | None | N | 0.295 | 0.107 | 0.132336055621 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 9.02E-06 | 0 |
| T/I | 32404 |
Fn3-124 |
6 | rs752957686 |
0.1017 | 0.243 | None | N | 0.295 | 0.107 | 0.132336055621 | gnomAD-4.0.0 | 2.75297E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.61901E-06 | 0 | 0 |
| E/K | 32504 |
Fn3-125 |
6 | rs768612570 |
0.1174 | -0.359 | 0.117 | N | 0.393 | 0.141 | 0.264081493735 | gnomAD-2.1.1 | 1.65E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 1.00827E-04 | None | 0 | 9.12E-06 | 0 |
| E/K | 32504 |
Fn3-125 |
6 | rs768612570 |
0.1174 | -0.359 | 0.117 | N | 0.393 | 0.141 | 0.264081493735 | gnomAD-3.1.2 | 1.31E-05 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 4.13565E-04 | 0 |
| E/K | 32504 |
Fn3-125 |
6 | rs768612570 |
0.1174 | -0.359 | 0.117 | N | 0.393 | 0.141 | 0.264081493735 | gnomAD-4.0.0 | 1.28914E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 2.40974E-06 | 1.21898E-04 | 0 |
| E/K | 32800 |
Fn3-127 |
6 | None | 0.2674 | None | 0.992 | N | 0.651 | 0.295 | 0.319686207203 | gnomAD-4.0.0 | 1.08029E-05 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.18125E-05 | 0 | 0 |
| S/G | 32901 |
Fn3-128 |
6 | None | 0.0853 | None | 0.805 | N | 0.475 | 0.182 | 0.229264304666 | gnomAD-4.0.0 | 6.84378E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 2.51965E-05 | None | 0 | 0 | 0 | 0 | 0 |
| S/I | 32901 |
Fn3-128 |
6 | None | 0.1639 | None | 0.983 | N | 0.778 | 0.266 | 0.358340041657 | gnomAD-4.0.0 | 3.60097E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 3.9375E-06 | 0 | 0 |
| S/R | 32901 |
Fn3-128 |
6 | rs1450732956 |
0.6754 | -0.475 | 0.967 | N | 0.732 | 0.264 | 0.31501682445 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.88E-06 | 0 |
| S/R | 32901 |
Fn3-128 |
6 | rs1450732956 |
0.6754 | -0.475 | 0.967 | N | 0.732 | 0.264 | 0.31501682445 | gnomAD-4.0.0 | 6.84378E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 8.99703E-07 | 0 | 0 |
| G/E | 33003 |
Fn3-129 |
6 | rs775787996 |
0.4722 | -2.11 | 1.0 | N | 0.877 | 0.391 | 0.458734620958 | gnomAD-2.1.1 | 4.08E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 3.37E-05 | None | 0 | 0 | 0 |
| G/E | 33003 |
Fn3-129 |
6 | rs775787996 |
0.4722 | -2.11 | 1.0 | N | 0.877 | 0.391 | 0.458734620958 | gnomAD-4.0.0 | 1.37369E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.0198E-07 | 1.17222E-05 | 0 |
| G/A | 33397 |
Fn3-131 |
6 | None | 0.1533 | None | 0.001 | N | 0.154 | 0.081 | 0.149567049428 | gnomAD-4.0.0 | 7.44605E-07 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 9.44194E-07 | 0 | 0 |
| G/D | 33397 |
Fn3-131 |
6 | rs1356361274 |
0.3181 | None | 0.324 | N | 0.541 | 0.122 | 0.178374595973 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 0 | 0 | 0 | 0 | None | 0 | 0 | 1.47E-05 | 0 | 0 |
| G/D | 33397 |
Fn3-131 |
6 | rs1356361274 |
0.3181 | None | 0.324 | N | 0.541 | 0.122 | 0.178374595973 | gnomAD-4.0.0 | 1.33768E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.77444E-06 | 0 | 0 |
| G/S | 33397 |
Fn3-131 |
6 | None | 0.1193 | None | 0.001 | N | 0.321 | 0.047 | 0.12205267543 | gnomAD-4.0.0 | 1.48799E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | 0 | 1.88726E-06 | 0 | 0 |
| R/K | 33694 |
Fn3-132 |
6 | rs747732590 |
0.0972 | -0.321 | 0.048 | N | 0.202 | 0.146 | 0.264547087235 | gnomAD-2.1.1 | 4.02E-06 | None | None | None | None | N | None | 0 | 0 | None | 0 | 0 | None | 0 | None | 0 | 8.87E-06 | 0 |
| R/K | 33694 |
Fn3-132 |
6 | rs747732590 |
0.0972 | -0.321 | 0.048 | N | 0.202 | 0.146 | 0.264547087235 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 2.41E-05 | 0 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/K | 33694 |
Fn3-132 |
6 | rs747732590 |
0.0972 | -0.321 | 0.048 | N | 0.202 | 0.146 | 0.264547087235 | gnomAD-4.0.0 | 5.12394E-06 | None | None | None | None | N | None | 1.69125E-05 | 0 | None | 0 | 0 | None | 0 | 0 | 4.78556E-06 | 0 | 2.84398E-05 |
| R/T | 33694 |
Fn3-132 |
6 | rs747732590 |
0.2559 | None | 0.993 | N | 0.715 | 0.288 | 0.568072681961 | gnomAD-3.1.2 | 6.57E-06 | None | None | None | None | N | None | 0 | 6.55E-05 | 0 | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
| R/T | 33694 |
Fn3-132 |
6 | rs747732590 |
0.2559 | None | 0.993 | N | 0.715 | 0.288 | 0.568072681961 | gnomAD-4.0.0 | 6.57065E-06 | None | None | None | None | N | None | 0 | 6.54707E-05 | None | 0 | 0 | None | 0 | 0 | 0 | 0 | 0 |
Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.