Structural position:

  • Domain Type: Fn3
  • Aligned Position: 4
  • Secondary Structure Element:
  • Secondary Structure Region:

SAVs

SAV Position (IC) Domain Position (Domain) RS
AlphaMissense (IC)
DUET
PolyPhen-2
Condel
Rhapsody
REVEL
MVP
Source
MAF
Disease
Zygosity
Site annotation
mCSM PPI
Predicted PPI site
Comments
AFR
AMR
AMS
ASJ
EAS
EUR
FIN
MDE
NFE
SAS
OTH
P/L 15761 Fn3-2 4 None 0.3246 None 0.961 D 0.788 0.464 0.669175797544 gnomAD-4.0.0 1.5949E-06 None None None None I None 0 0 None 0 0 None 0 0 2.86357E-06 0 0
P/S 15761 Fn3-2 4 rs766763223 0.1772 -1.568 0.925 D 0.715 0.386 None gnomAD-2.1.1 4.06E-06 None None None None I None 6.48E-05 0 None 0 0 None 0 None 0 0 0
P/S 15761 Fn3-2 4 rs766763223 0.1772 -1.568 0.925 D 0.715 0.386 None gnomAD-3.1.2 6.59E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/S 15761 Fn3-2 4 rs766763223 0.1772 -1.568 0.925 D 0.715 0.386 None gnomAD-4.0.0 6.58579E-06 None None None None I None 2.41639E-05 0 None 0 0 None 0 0 0 0 0
P/S 15862 Fn3-3 4 rs879096040 0.1804 None 1.0 N 0.866 0.366 0.331619326243 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 2.07211E-04 0
P/S 15862 Fn3-3 4 rs879096040 0.1804 None 1.0 N 0.866 0.366 0.331619326243 gnomAD-4.0.0 3.78513E-06 None None None None I None 0 0 None 0 0 None 0 0 8.53596E-07 5.92459E-05 0
P/T 15862 Fn3-3 4 None 0.2449 None 1.0 D 0.859 0.412 0.567785321435 gnomAD-4.0.0 1.39536E-06 None None None None I None 0 0 None 0 0 None 0 0 9.06093E-07 1.25679E-05 0
A/V 16058 Fn3-4 4 rs767579172 0.1711 -0.625 0.977 D 0.823 0.425 0.420447328233 gnomAD-4.0.0 2.05454E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80008E-06 1.16077E-05 0
P/S 16354 Fn3-6 4 rs747402071 0.443 -1.599 1.0 D 0.823 0.454 0.434934176536 gnomAD-2.1.1 3.6E-05 None None None None N None 0 0 None 0 0 None 6.56E-05 None 0 6.33E-05 0
P/S 16354 Fn3-6 4 rs747402071 0.443 -1.599 1.0 D 0.823 0.454 0.434934176536 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.95E-05 0 0
P/S 16354 Fn3-6 4 rs747402071 0.443 -1.599 1.0 D 0.823 0.454 0.434934176536 gnomAD-4.0.0 4.71404E-05 None None None None N None 0 0 None 0 0 None 0 0 5.59729E-05 7.69484E-05 4.80877E-05
P/L 16453 Fn3-7 4 rs376498195 0.3645 -0.74 0.989 D 0.803 0.464 None gnomAD-2.1.1 1.45E-05 None None None None N None 1.66196E-04 0 None 0 0 None 0 None 0 0 0
P/L 16453 Fn3-7 4 rs376498195 0.3645 -0.74 0.989 D 0.803 0.464 None gnomAD-3.1.2 1.32E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/L 16453 Fn3-7 4 rs376498195 0.3645 -0.74 0.989 D 0.803 0.464 None gnomAD-4.0.0 5.16582E-06 None None None None N None 6.81013E-05 0 None 0 0 None 0 0 0 0 0
P/T 16453 Fn3-7 4 rs200121902 0.2999 -1.287 0.989 D 0.723 0.424 None gnomAD-2.1.1 1.85035E-04 None None None None N None 2.03539E-03 2.9E-05 None 0 0 None 0 None 0 7.9E-06 0
P/T 16453 Fn3-7 4 rs200121902 0.2999 -1.287 0.989 D 0.723 0.424 None gnomAD-3.1.2 5.39744E-04 None None None None N None 1.93171E-03 0 0 0 0 None 0 0 1.47E-05 0 4.78469E-04
P/T 16453 Fn3-7 4 rs200121902 0.2999 -1.287 0.989 D 0.723 0.424 None 1000 genomes 5.99042E-04 None None None None N None 1.5E-03 1.4E-03 None None 0 0 None None None 0 None
P/T 16453 Fn3-7 4 rs200121902 0.2999 -1.287 0.989 D 0.723 0.424 None gnomAD-4.0.0 9.64065E-05 None None None None N None 1.96882E-03 1.68936E-05 None 0 0 None 0 0 8.49749E-07 0 9.64816E-05
P/A 16554 Fn3-8 4 rs1169803505 0.0845 -1.927 0.122 N 0.483 0.102 0.183819452728 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/A 16554 Fn3-8 4 rs1169803505 0.0845 -1.927 0.122 N 0.483 0.102 0.183819452728 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/A 16554 Fn3-8 4 rs1169803505 0.0845 -1.927 0.122 N 0.483 0.102 0.183819452728 gnomAD-4.0.0 5.13306E-06 None None None None N None 0 0 None 0 0 None 0 0 9.58612E-06 0 0
P/L 16554 Fn3-8 4 None 0.3858 None 0.071 D 0.639 0.428 0.504789117978 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/A 16654 Fn3-9 4 rs1362265469 0.1191 -1.498 0.025 N 0.429 0.174 0.130388298395 gnomAD-2.1.1 4.21E-06 None None None None N None 0 3E-05 None 0 0 None 0 None 0 0 0
P/A 16654 Fn3-9 4 rs1362265469 0.1191 -1.498 0.025 N 0.429 0.174 0.130388298395 gnomAD-4.0.0 1.60804E-06 None None None None N None 0 2.34313E-05 None 0 0 None 0 0 0 0 0
P/S 16654 Fn3-9 4 rs1362265469 0.2936 -1.598 0.698 D 0.765 0.298 0.208816687407 gnomAD-2.1.1 4.21E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.38E-06 0
P/S 16654 Fn3-9 4 rs1362265469 0.2936 -1.598 0.698 D 0.765 0.298 0.208816687407 gnomAD-4.0.0 1.60804E-06 None None None None N None 0 0 None 0 0 None 0 0 2.87247E-06 0 0
P/T 16654 Fn3-9 4 None 0.4403 None 0.032 D 0.517 0.286 0.285316908763 gnomAD-4.0.0 6.43217E-06 None None None None N None 0 0 None 0 1.11882E-04 None 0 0 0 0 0
P/L 16855 Fn3-11 4 rs767521432 0.584 -0.863 0.999 D 0.865 0.423 0.677064111946 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.93E-06 0
P/L 16855 Fn3-11 4 rs767521432 0.584 -0.863 0.999 D 0.865 0.423 0.677064111946 gnomAD-4.0.0 6.84628E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99821E-07 0 0
P/R 16855 Fn3-11 4 None 0.6602 None 0.999 D 0.888 0.418 0.476364732183 gnomAD-4.0.0 1.36926E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.32137E-05 0
P/S 16855 Fn3-11 4 None 0.4937 None 0.998 D 0.837 0.32 0.347217280506 gnomAD-4.0.0 1.59346E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43468E-05 0
P/Q 17050 Fn3-12 4 None 0.1472 None 0.362 N 0.346 0.144 0.279370189704 gnomAD-4.0.0 4.10941E-06 None None None None N None 0 0 None 0 0 None 0 0 4.50019E-06 0 1.65898E-05
P/L 17150 Fn3-13 4 rs764792715 0.6576 -0.838 1.0 D 0.911 0.503 0.673603381577 gnomAD-2.1.1 4.06E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.95E-06 0
P/L 17150 Fn3-13 4 rs764792715 0.6576 -0.838 1.0 D 0.911 0.503 0.673603381577 gnomAD-3.1.2 6.58E-06 None None None None I None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/L 17150 Fn3-13 4 rs764792715 0.6576 -0.838 1.0 D 0.911 0.503 0.673603381577 gnomAD-4.0.0 3.72502E-06 None None None None I None 4.02209E-05 0 None 0 0 None 0 0 1.69684E-06 0 1.60519E-05
P/R 17372 Fn3-14 4 None 0.5001 None 1.0 N 0.873 0.504 0.484837542351 gnomAD-4.0.0 2.05925E-06 None None None None I None 0 0 None 0 0 None 0 0 2.70016E-06 0 0
P/S 17372 Fn3-14 4 rs2055579042 0.3834 None 0.999 N 0.829 0.383 0.362361684037 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/S 17372 Fn3-14 4 rs2055579042 0.3834 None 0.999 N 0.829 0.383 0.362361684037 gnomAD-4.0.0 6.58215E-06 None None None None I None 2.41476E-05 0 None 0 0 None 0 0 0 0 0
P/T 17372 Fn3-14 4 None 0.3797 None 0.999 N 0.831 0.393 0.433823933641 gnomAD-4.0.0 1.37295E-06 None None None None I None 0 0 None 0 0 None 0 0 1.80013E-06 0 0
A/V 17473 Fn3-15 4 rs1408028554 0.302 -0.736 0.989 N 0.717 0.32 0.400613892164 gnomAD-4.0.0 2.08187E-06 None None None None N None 0 2.45242E-05 None 0 0 None 0 0 1.81357E-06 0 0
G/E 17572 Fn3-16 4 rs867992198 0.7864 None 1.0 N 0.753 0.397 0.37262878642 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
G/E 17572 Fn3-16 4 rs867992198 0.7864 None 1.0 N 0.753 0.397 0.37262878642 gnomAD-4.0.0 6.57929E-06 None None None None N None 2.40964E-05 0 None 0 0 None 0 0 0 0 0
P/L 17767 Fn3-17 4 rs1465233091 0.4834 None 1.0 N 0.795 0.46 0.749854518339 gnomAD-4.0.0 2.05427E-06 None None None None N None 0 0 None 0 0 None 0 0 2.69957E-06 0 0
P/S 17767 Fn3-17 4 None 0.4201 None 1.0 N 0.754 0.378 0.439551795455 gnomAD-4.0.0 6.84757E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99855E-07 0 0
P/T 17767 Fn3-17 4 rs1243704778 0.4444 None 1.0 N 0.754 0.457 0.547893116657 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
S/A 17865 Fn3-18 4 rs756689912 0.0702 -0.278 0.001 N 0.275 0.046 0.0297737177859 gnomAD-2.1.1 4.86E-06 None None None None N None 0 4.06E-05 None 0 0 None 0 None 0 0 0
S/A 17865 Fn3-18 4 rs756689912 0.0702 -0.278 0.001 N 0.275 0.046 0.0297737177859 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.56E-05 0 0 0 None 0 0 0 0 0
S/A 17865 Fn3-18 4 rs756689912 0.0702 -0.278 0.001 N 0.275 0.046 0.0297737177859 gnomAD-4.0.0 6.58042E-06 None None None None N None 0 6.55652E-05 None 0 0 None 0 0 0 0 0
S/C 17865 Fn3-18 4 rs753095229 0.1241 -0.92 0.928 N 0.772 0.186 0.356484672536 gnomAD-2.1.1 4.85E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.01E-05 0
S/C 17865 Fn3-18 4 rs753095229 0.1241 -0.92 0.928 N 0.772 0.186 0.356484672536 gnomAD-4.0.0 2.16502E-06 None None None None N None 0 0 None 0 0 None 0 0 2.80031E-06 0 0
S/F 17865 Fn3-18 4 rs753095229 0.4143 None 0.193 N 0.807 0.211 0.451786746415 gnomAD-4.0.0 2.16502E-06 None None None None N None 0 0 None 0 0 None 0 0 0 4.20486E-05 0
S/T 17865 Fn3-18 4 rs756689912 0.1952 -0.726 0.09 N 0.636 0.04 0.0611884634855 gnomAD-2.1.1 9.72E-06 None None None None N None 0 0 None 0 0 None 0 None 0 2.03E-05 0
S/T 17865 Fn3-18 4 rs756689912 0.1952 -0.726 0.09 N 0.636 0.04 0.0611884634855 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 0 0 4.42E-05 0 0
S/T 17865 Fn3-18 4 rs756689912 0.1952 -0.726 0.09 N 0.636 0.04 0.0611884634855 gnomAD-4.0.0 1.04082E-05 None None None None N None 0 0 None 0 0 None 0 0 1.40469E-05 0 0
P/A 18068 Fn3-19 4 None 0.1235 None 1.0 N 0.833 0.412 0.327686398923 gnomAD-4.0.0 4.79658E-06 None None None None N None 0 0 None 0 0 None 0 0 6.30217E-06 0 0
P/S 18068 Fn3-19 4 None 0.4199 None 1.0 N 0.843 0.447 0.401042353794 gnomAD-4.0.0 6.85225E-07 None None None None N None 0 0 None 0 0 None 0 0 9.0031E-07 0 0
P/H 18169 Fn3-20 4 rs2054202479 0.4044 None 1.0 N 0.899 0.446 0.648488047482 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/H 18169 Fn3-20 4 rs2054202479 0.4044 None 1.0 N 0.899 0.446 0.648488047482 gnomAD-4.0.0 6.58094E-06 None None None None I None 2.41499E-05 0 None 0 0 None 0 0 0 0 0
P/L 18169 Fn3-20 4 None 0.2868 None 0.987 N 0.882 0.446 0.776041197187 gnomAD-4.0.0 2.05477E-06 None None None None I None 0 0 None 0 0 None 0 0 1.80026E-06 0 1.65898E-05
P/R 18169 Fn3-20 4 None 0.2907 None 0.997 N 0.891 0.45 0.600640161457 gnomAD-4.0.0 6.84925E-07 None None None None I None 0 0 None 0 0 None 1.87498E-05 0 0 0 0
P/A 18275 Fn3-21 4 rs765408419 0.0962 -1.615 None N 0.355 0.101 0.12205267543 gnomAD-2.1.1 2.18E-05 None None None None N None 0 1.96592E-04 None 0 0 None 0 None 0 0 0
P/A 18275 Fn3-21 4 rs765408419 0.0962 -1.615 None N 0.355 0.101 0.12205267543 gnomAD-4.0.0 5.64364E-06 None None None None N None 0 1.22249E-04 None 0 0 None 0 0 0 0 0
P/L 18275 Fn3-21 4 None 0.257 None 0.027 N 0.636 0.368 0.53046153047 gnomAD-4.0.0 1.87755E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.80044E-05 0
P/L 18482 Fn3-22 4 None 0.2255 None 0.998 N 0.829 0.484 0.65545073463 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
P/L 18582 Fn3-23 4 rs201194435 0.6803 -0.894 0.142 D 0.699 0.414 None gnomAD-2.1.1 8.93E-05 None None None None N None 4.34E-05 4.48E-05 None 0 0 None 0 None 0 1.53175E-04 1.92086E-04
P/L 18582 Fn3-23 4 rs201194435 0.6803 -0.894 0.142 D 0.699 0.414 None gnomAD-3.1.2 9.21E-05 None None None None N None 2.42E-05 6.56E-05 0 0 0 None 0 0 1.7658E-04 0 0
P/L 18582 Fn3-23 4 rs201194435 0.6803 -0.894 0.142 D 0.699 0.414 None gnomAD-4.0.0 6.67409E-05 None None None None N None 1.39427E-05 4.42674E-05 None 0 0 None 8.22368E-05 0 8.05453E-05 0 3.40692E-05
P/S 18582 Fn3-23 4 rs1213775355 0.3995 -1.947 0.994 N 0.861 0.367 0.314716216878 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14837E-04 0 None 0 0 None 0 None 0 0 0
P/S 18582 Fn3-23 4 rs1213775355 0.3995 -1.947 0.994 N 0.861 0.367 0.314716216878 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/S 18582 Fn3-23 4 rs1213775355 0.3995 -1.947 0.994 N 0.861 0.367 0.314716216878 gnomAD-4.0.0 6.57947E-06 None None None None N None 2.41558E-05 0 None 0 0 None 0 0 0 0 0
P/L 18787 Fn3-24 4 None 0.1743 None 0.995 N 0.905 0.409 0.631724915229 gnomAD-4.0.0 7.24553E-07 None None None None N None 0 0 None 0 0 None 0 0 9.30271E-07 0 0
P/R 18787 Fn3-24 4 rs1227865413 0.2913 -0.946 1.0 N 0.941 0.491 0.512595481341 gnomAD-2.1.1 5.38E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.11E-05 0
P/R 18787 Fn3-24 4 rs1227865413 0.2913 -0.946 1.0 N 0.941 0.491 0.512595481341 gnomAD-4.0.0 2.17366E-06 None None None None N None 0 0 None 0 0 None 0 0 2.79081E-06 0 0
P/S 18787 Fn3-24 4 None 0.2778 None 0.999 N 0.922 0.32 0.331365685468 gnomAD-4.0.0 1.82357E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.85957E-05 0
G/D 18991 Fn3-26 4 rs1359328880 0.8319 -1.674 1.0 N 0.806 0.27 0.226586394389 gnomAD-2.1.1 3.19E-05 None None None None I None 1.14784E-04 0 None 0 0 None 0 None 0 0 0
G/D 18991 Fn3-26 4 rs1359328880 0.8319 -1.674 1.0 N 0.806 0.27 0.226586394389 gnomAD-3.1.2 1.32E-05 None None None None I None 2.42E-05 0 0 0 0 None 0 0 1.47E-05 0 0
G/D 18991 Fn3-26 4 rs1359328880 0.8319 -1.674 1.0 N 0.806 0.27 0.226586394389 gnomAD-4.0.0 1.31671E-05 None None None None I None 2.41733E-05 0 None 0 0 None 0 0 1.47137E-05 0 0
P/S 19186 Fn3-27 4 None 0.2275 None 1.0 N 0.839 0.432 0.493628743246 gnomAD-4.0.0 1.38175E-06 None None None None I None 0 0 None 0 0 None 0 0 1.80945E-06 0 0
R/C 19287 Fn3-28 4 rs372710684 0.7267 -0.742 1.0 N 0.847 0.402 None gnomAD-2.1.1 3.31E-05 None None None None N None 6.52E-05 0 None 0 0 None 0 None 0 6.36E-05 0
R/C 19287 Fn3-28 4 rs372710684 0.7267 -0.742 1.0 N 0.847 0.402 None gnomAD-3.1.2 1.97E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 1.47E-05 0 0
R/C 19287 Fn3-28 4 rs372710684 0.7267 -0.742 1.0 N 0.847 0.402 None gnomAD-4.0.0 1.18486E-05 None None None None N None 4.03573E-05 0 None 0 0 None 0 0 1.36229E-05 0 0
R/G 19287 Fn3-28 4 rs372710684 0.9051 None 1.0 N 0.806 0.35 0.560115663565 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.55E-05 0 0 0 None 0 0 0 0 0
R/G 19287 Fn3-28 4 rs372710684 0.9051 None 1.0 N 0.806 0.35 0.560115663565 gnomAD-4.0.0 6.57748E-06 None None None None N None 0 6.5505E-05 None 0 0 None 0 0 0 0 0
R/H 19287 Fn3-28 4 rs371422299 0.5889 -1.388 1.0 N 0.757 0.374 0.269111216191 gnomAD-2.1.1 6.61E-05 None None None None N None 0 2.39392E-04 None 1.04844E-04 1.13366E-04 None 0 None 0 2.73E-05 3.4188E-04
R/H 19287 Fn3-28 4 rs371422299 0.5889 -1.388 1.0 N 0.757 0.374 0.269111216191 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 1.93874E-04 None 0 0 2.94E-05 0 0
R/H 19287 Fn3-28 4 rs371422299 0.5889 -1.388 1.0 N 0.757 0.374 0.269111216191 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
R/H 19287 Fn3-28 4 rs371422299 0.5889 -1.388 1.0 N 0.757 0.374 0.269111216191 gnomAD-4.0.0 2.80602E-05 None None None None N None 2.68565E-05 1.70137E-04 None 6.86153E-05 6.72284E-05 None 0 3.34113E-04 1.53255E-05 3.34971E-05 8.06088E-05
P/L 19482 Fn3-29 4 rs746380279 0.1535 -0.78 1.0 N 0.892 0.481 0.710211490884 gnomAD-2.1.1 4.12E-06 None None None None I None 0 0 None 0 0 None 0 None 0 0 1.70184E-04
P/L 19482 Fn3-29 4 rs746380279 0.1535 -0.78 1.0 N 0.892 0.481 0.710211490884 gnomAD-4.0.0 2.05932E-06 None None None None I None 0 0 None 0 0 None 0 0 2.701E-06 0 0
P/Q 19482 Fn3-29 4 None 0.2278 None 1.0 N 0.883 0.465 0.522344865107 gnomAD-4.0.0 6.86439E-07 None None None None I None 0 0 None 0 0 None 0 0 9.00333E-07 0 0
P/S 19482 Fn3-29 4 rs758990147 0.2396 -1.792 1.0 N 0.886 0.433 0.425148423609 gnomAD-2.1.1 4.09E-06 None None None None I None 0 0 None 0 5.74E-05 None 0 None 0 0 0
P/S 19482 Fn3-29 4 rs758990147 0.2396 -1.792 1.0 N 0.886 0.433 0.425148423609 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 3.87898E-04 None 0 0 0 0 0
P/S 19482 Fn3-29 4 rs758990147 0.2396 -1.792 1.0 N 0.886 0.433 0.425148423609 gnomAD-4.0.0 1.31728E-05 None None None None I None 0 0 None 0 3.87898E-04 None 0 0 0 0 0
A/T 19582 Fn3-30 4 None 0.2552 None 1.0 N 0.799 0.441 0.534719010399 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/R 19683 Fn3-31 4 rs768307125 0.4939 -0.608 1.0 N 0.921 0.494 0.534620942121 gnomAD-2.1.1 6.47E-05 None None None None N None 0 0 None 0 0 None 0 None 3.71506E-04 6.25E-05 1.66834E-04
P/R 19683 Fn3-31 4 rs768307125 0.4939 -0.608 1.0 N 0.921 0.494 0.534620942121 gnomAD-3.1.2 3.29E-05 None None None None N None 0 0 0 0 0 None 2.83286E-04 0 2.94E-05 0 0
P/R 19683 Fn3-31 4 rs768307125 0.4939 -0.608 1.0 N 0.921 0.494 0.534620942121 gnomAD-4.0.0 7.05856E-05 None None None None N None 0 0 None 0 0 None 5.18037E-04 0 4.07227E-05 0 1.42434E-04
P/S 19880 Fn3-32 4 rs778795921 0.2138 -1.502 1.0 N 0.823 0.454 0.445007932271 gnomAD-2.1.1 8.26E-06 None None None None N None 0 0 None 0 0 None 6.79E-05 None 0 0 0
P/S 19880 Fn3-32 4 rs778795921 0.2138 -1.502 1.0 N 0.823 0.454 0.445007932271 gnomAD-4.0.0 6.17335E-06 None None None None N None 0 0 None 0 0 None 0 0 0 9.38064E-05 1.66141E-05
P/T 19880 Fn3-32 4 None 0.2109 None 1.0 D 0.828 0.463 0.54626238531 gnomAD-4.0.0 1.37185E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80065E-06 0 0
P/A 19980 Fn3-33 4 None 0.1719 None 1.0 N 0.839 0.345 0.301122078929 gnomAD-4.0.0 1.60523E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86959E-06 0 0
P/L 20274 Fn3-35 4 rs72646845 0.1707 -0.851 0.997 N 0.813 0.39 None gnomAD-2.1.1 3.34794E-03 None None None None I None 2.48077E-04 8.50003E-04 None 1.68801E-02 0 None 1.74784E-02 None 1.20298E-04 1.27875E-03 3.5251E-03
P/L 20274 Fn3-35 4 rs72646845 0.1707 -0.851 0.997 N 0.813 0.39 None gnomAD-3.1.2 1.38743E-03 None None None None I None 1.44774E-04 5.90087E-04 2.19298E-03 1.35525E-02 0 None 4.70633E-04 0 9.41315E-04 1.59552E-02 4.78469E-04
P/L 20274 Fn3-35 4 rs72646845 0.1707 -0.851 0.997 N 0.813 0.39 None 1000 genomes 2.99521E-03 None None None None I None 0 0 None None 0 0 None None None 1.53E-02 None
P/L 20274 Fn3-35 4 rs72646845 0.1707 -0.851 0.997 N 0.813 0.39 None gnomAD-4.0.0 2.03316E-03 None None None None I None 2E-04 8.17348E-04 None 1.65393E-02 0 None 9.37588E-05 1.17511E-02 8.11115E-04 1.68223E-02 2.54718E-03
P/L 20374 Fn3-36 4 rs372969669 0.5165 -0.855 1.0 N 0.909 0.389 None gnomAD-2.1.1 7.16E-06 None None None None I None 8.27E-05 0 None 0 0 None 0 None 0 0 0
P/L 20374 Fn3-36 4 rs372969669 0.5165 -0.855 1.0 N 0.909 0.389 None gnomAD-3.1.2 1.32E-05 None None None None I None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/L 20374 Fn3-36 4 rs372969669 0.5165 -0.855 1.0 N 0.909 0.389 None gnomAD-4.0.0 1.31551E-05 None None None None I None 4.82928E-05 0 None 0 0 None 0 0 0 0 0
P/S 20374 Fn3-36 4 rs1353471700 0.4784 -1.934 1.0 N 0.873 0.334 0.437850553699 gnomAD-2.1.1 3.19E-05 None None None None I None 0 0 None 0 0 None 0 None 0 6.49E-05 0
P/S 20374 Fn3-36 4 rs1353471700 0.4784 -1.934 1.0 N 0.873 0.334 0.437850553699 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 20374 Fn3-36 4 rs1353471700 0.4784 -1.934 1.0 N 0.873 0.334 0.437850553699 gnomAD-4.0.0 2.56508E-06 None None None None I None 0 0 None 0 0 None 1.57001E-05 0 2.39543E-06 0 0
P/A 20572 Fn3-37 4 None 0.1211 None 0.989 N 0.728 0.402 0.306695030598 gnomAD-4.0.0 7.52908E-06 None None None None N None 0 0 None 0 0 None 0 0 9.89629E-06 0 0
P/S 20572 Fn3-37 4 rs1333184630 0.2523 -1.49 0.989 N 0.77 0.411 0.374076547971 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/S 20572 Fn3-37 4 rs1333184630 0.2523 -1.49 0.989 N 0.77 0.411 0.374076547971 gnomAD-4.0.0 6.84463E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.15969E-05 0
P/T 20572 Fn3-37 4 rs1333184630 0.2362 None 0.997 N 0.783 0.476 0.468504517574 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 20572 Fn3-37 4 rs1333184630 0.2362 None 0.997 N 0.783 0.476 0.468504517574 gnomAD-4.0.0 6.57765E-06 None None None None N None 0 0 None 0 0 None 0 0 1.47158E-05 0 0
E/G 20671 Fn3-38 4 None 0.4779 None 1.0 N 0.795 0.322 0.44318313171 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
E/K 20671 Fn3-38 4 rs770684884 0.3145 -0.44 0.999 N 0.702 0.339 0.332133492242 gnomAD-2.1.1 1.77186E-04 None None None None N None 0 1.27536E-03 None 0 0 None 0 None 0 0 0
E/K 20671 Fn3-38 4 rs770684884 0.3145 -0.44 0.999 N 0.702 0.339 0.332133492242 gnomAD-3.1.2 1.97E-05 None None None None N None 0 1.96618E-04 0 0 0 None 0 0 0 0 0
E/K 20671 Fn3-38 4 rs770684884 0.3145 -0.44 0.999 N 0.702 0.339 0.332133492242 gnomAD-4.0.0 3.47089E-05 None None None None N None 0 9.0042E-04 None 0 0 None 0 0 8.47735E-07 0 1.60133E-05
P/S 20867 Fn3-39 4 rs374611035 0.2725 -1.305 0.955 N 0.697 0.396 0.379193981924 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.91E-06 0
P/S 20867 Fn3-39 4 rs374611035 0.2725 -1.305 0.955 N 0.697 0.396 0.379193981924 gnomAD-4.0.0 6.8475E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99559E-07 0 0
P/T 20867 Fn3-39 4 rs374611035 0.2148 -1.236 0.993 N 0.735 0.367 None gnomAD-2.1.1 2.15E-05 None None None None N None 2.47995E-04 0 None 0 0 None 0 None 0 0 0
P/T 20867 Fn3-39 4 rs374611035 0.2148 -1.236 0.993 N 0.735 0.367 None gnomAD-3.1.2 3.29E-05 None None None None N None 1.20656E-04 0 0 0 0 None 0 0 0 0 0
P/T 20867 Fn3-39 4 rs374611035 0.2148 -1.236 0.993 N 0.735 0.367 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
P/T 20867 Fn3-39 4 rs374611035 0.2148 -1.236 0.993 N 0.735 0.367 None gnomAD-4.0.0 5.58123E-06 None None None None N None 1.19968E-04 0 None 0 0 None 0 0 0 0 0
R/C 20966 Fn3-40 4 rs767887086 0.1092 -0.7 0.999 N 0.471 0.345 0.562540394707 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 4.65E-05 0 0
R/C 20966 Fn3-40 4 rs767887086 0.1092 -0.7 0.999 N 0.471 0.345 0.562540394707 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
R/C 20966 Fn3-40 4 rs767887086 0.1092 -0.7 0.999 N 0.471 0.345 0.562540394707 gnomAD-4.0.0 9.91825E-06 None None None None N None 0 0 None 0 0 None 1.56279E-05 0 1.18686E-05 0 1.60164E-05
R/G 20966 Fn3-40 4 None 0.2343 None 0.954 N 0.445 0.353 0.504480301252 gnomAD-4.0.0 1.36874E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79918E-06 0 0
R/H 20966 Fn3-40 4 rs1174185176 0.1049 -1.379 0.998 N 0.347 0.257 0.240491677333 gnomAD-2.1.1 8.06E-06 None None None None N None 1.30565E-04 0 None 0 0 None 0 None 0 0 0
R/H 20966 Fn3-40 4 rs1174185176 0.1049 -1.379 0.998 N 0.347 0.257 0.240491677333 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/H 20966 Fn3-40 4 rs1174185176 0.1049 -1.379 0.998 N 0.347 0.257 0.240491677333 gnomAD-4.0.0 6.19891E-06 None None None None N None 4.00673E-05 1.66845E-05 None 3.37975E-05 0 None 0 0 4.2388E-06 0 0
P/A 21067 Fn3-41 4 None 0.1592 None 1.0 N 0.818 0.376 0.239901079897 gnomAD-4.0.0 1.40824E-06 None None None None N None 0 0 None 0 0 None 0 0 1.83937E-06 0 0
P/L 21067 Fn3-41 4 rs1479721183 0.3147 -0.882 1.0 N 0.893 0.545 0.773205105146 gnomAD-2.1.1 4.49E-06 None None None None N None 0 3.18E-05 None 0 0 None 0 None 0 0 0
P/L 21067 Fn3-41 4 rs1479721183 0.3147 -0.882 1.0 N 0.893 0.545 0.773205105146 gnomAD-4.0.0 7.04641E-07 None None None None N None 0 2.41022E-05 None 0 0 None 0 0 0 0 0
P/R 21067 Fn3-41 4 None 0.5503 None 1.0 N 0.896 0.566 0.609343871639 gnomAD-4.0.0 7.0464E-07 None None None None N None 0 0 None 0 0 None 0 0 9.20105E-07 0 0
P/T 21067 Fn3-41 4 None 0.38 None 1.0 N 0.827 0.486 0.604394614948 gnomAD-4.0.0 7.04121E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.25172E-05 0
P/R 21369 Fn3-43 4 rs778476727 0.8733 -1.218 1.0 N 0.896 0.434 0.59800879648 gnomAD-2.1.1 4.06E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.97E-06 0
P/R 21369 Fn3-43 4 rs778476727 0.8733 -1.218 1.0 N 0.896 0.434 0.59800879648 gnomAD-4.0.0 1.59662E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86453E-06 0 0
P/S 21369 Fn3-43 4 rs1388682620 0.6453 -2.314 1.0 N 0.839 0.388 0.350964488264 gnomAD-2.1.1 3.19E-05 None None None None N None 1.14916E-04 0 None 0 0 None 0 None 0 0 0
P/S 21369 Fn3-43 4 rs1388682620 0.6453 -2.314 1.0 N 0.839 0.388 0.350964488264 gnomAD-3.1.2 6.58E-06 None None None None N None 2.42E-05 0 0 0 0 None 0 0 0 0 0
P/S 21369 Fn3-43 4 rs1388682620 0.6453 -2.314 1.0 N 0.839 0.388 0.350964488264 gnomAD-4.0.0 6.58181E-06 None None None None N None 2.41569E-05 0 None 0 0 None 0 0 0 0 0
P/L 21562 Fn3-44 4 None 0.2028 None 1.0 N 0.711 0.436 0.690156929516 gnomAD-4.0.0 6.84508E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.16058E-05 0
P/R 21562 Fn3-44 4 rs1213776805 0.3612 None 1.0 N 0.719 0.457 0.51759925163 gnomAD-3.1.2 6.57E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/R 21562 Fn3-44 4 rs1213776805 0.3612 None 1.0 N 0.719 0.457 0.51759925163 gnomAD-4.0.0 6.57497E-06 None None None None I None 2.41324E-05 0 None 0 0 None 0 0 0 0 0
E/D 21662 Fn3-45 4 rs1368089730 0.4377 -1.275 0.979 N 0.628 0.308 0.260735089382 gnomAD-2.1.1 8.07E-06 None None None None N None 0 5.82E-05 None 0 0 None 0 None 0 0 0
E/D 21662 Fn3-45 4 rs1368089730 0.4377 -1.275 0.979 N 0.628 0.308 0.260735089382 gnomAD-4.0.0 3.19107E-06 None None None None N None 0 4.58253E-05 None 0 0 None 0 0 0 0 0
E/G 21662 Fn3-45 4 None 0.2763 None 0.919 N 0.735 0.321 0.364342057095 gnomAD-4.0.0 1.59544E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43616E-05 0
E/K 21662 Fn3-45 4 rs2048514000 0.2185 None 0.958 N 0.626 0.351 0.284150004643 gnomAD-4.0.0 3.42543E-06 None None None None N None 0 0 None 0 1.01235E-04 None 0 0 9.00387E-07 0 0
P/L 21760 Fn3-46 4 rs1236566550 0.3181 None 1.0 N 0.89 0.467 0.686334916094 gnomAD-4.0.0 4.96751E-06 None None None None N None 6.2348E-05 2.56739E-05 None 4.12201E-05 0 None 0 0 1.84831E-06 1.27632E-05 0
P/R 21760 Fn3-46 4 None 0.3651 None 1.0 N 0.914 0.433 0.487772906946 gnomAD-4.0.0 7.09636E-07 None None None None N None 0 0 None 0 0 None 0 0 0 1.27632E-05 0
P/T 21760 Fn3-46 4 None 0.2292 None 1.0 N 0.842 0.345 0.408036853922 gnomAD-4.0.0 2.85383E-06 None None None None N None 0 0 None 0 0 None 0 0 3.70624E-06 0 0
P/L 21959 Fn3-47 4 None 0.4308 None 1.0 D 0.869 0.469 0.657373984822 gnomAD-4.0.0 6.87087E-07 None None None None N None 0 0 None 0 0 None 0 0 9.02582E-07 0 0
P/R 21959 Fn3-47 4 None 0.5159 None 1.0 N 0.893 0.477 0.486851695374 gnomAD-4.0.0 1.37417E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80516E-06 0 0
R/C 22058 Fn3-48 4 rs199643269 0.1381 -0.454 0.997 N 0.341 0.284 None gnomAD-2.1.1 1.113E-04 None None None None N None 7.96579E-04 6.08E-05 None 0 0 None 7.17E-05 None 0 4.82E-05 1.44844E-04
R/C 22058 Fn3-48 4 rs199643269 0.1381 -0.454 0.997 N 0.341 0.284 None gnomAD-3.1.2 3.88224E-04 None None None None N None 1.30365E-03 6.57E-05 0 0 0 None 0 0 4.41E-05 0 4.78927E-04
R/C 22058 Fn3-48 4 rs199643269 0.1381 -0.454 0.997 N 0.341 0.284 None 1000 genomes 1.99681E-04 None None None None N None 8E-04 0 None None 0 0 None None None 0 None
R/C 22058 Fn3-48 4 rs199643269 0.1381 -0.454 0.997 N 0.341 0.284 None gnomAD-4.0.0 8.41867E-05 None None None None N None 1.18784E-03 8.75289E-05 None 0 0 None 0 0 2.63325E-05 5.65713E-05 9.66713E-05
R/H 22058 Fn3-48 4 rs753077711 0.1249 -1.206 0.971 N 0.381 0.206 0.306053231325 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
R/H 22058 Fn3-48 4 rs753077711 0.1249 -1.206 0.971 N 0.381 0.206 0.306053231325 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
R/H 22058 Fn3-48 4 rs753077711 0.1249 -1.206 0.971 N 0.381 0.206 0.306053231325 gnomAD-4.0.0 3.73232E-06 None None None None N None 0 0 None 0 2.23774E-05 None 0 0 1.69746E-06 3.35751E-05 0
R/L 22058 Fn3-48 4 rs753077711 0.227 0.055 0.465 N 0.325 0.168 0.371157983038 gnomAD-2.1.1 4.13E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.09E-06 0
R/L 22058 Fn3-48 4 rs753077711 0.227 0.055 0.465 N 0.325 0.168 0.371157983038 gnomAD-4.0.0 2.06103E-06 None None None None N None 0 0 None 0 0 None 0 0 2.70212E-06 0 0
R/S 22058 Fn3-48 4 None 0.3595 None 0.465 N 0.244 0.235 0.268660756437 gnomAD-4.0.0 1.3779E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80296E-06 0 0
P/S 22159 Fn3-49 4 rs1471770452 0.4205 -1.325 1.0 N 0.843 0.41 0.361160317528 gnomAD-2.1.1 4.43E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.82E-06 0
P/S 22159 Fn3-49 4 rs1471770452 0.4205 -1.325 1.0 N 0.843 0.41 0.361160317528 gnomAD-4.0.0 3.27065E-06 None None None None N None 0 0 None 0 0 None 0 0 2.9244E-06 0 3.09521E-05
P/S 22357 Fn3-50 4 rs1446351991 0.2679 -1.29 1.0 N 0.805 0.487 0.405560941015 gnomAD-2.1.1 8.08E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.79E-05 0
P/S 22357 Fn3-50 4 rs1446351991 0.2679 -1.29 1.0 N 0.805 0.487 0.405560941015 gnomAD-4.0.0 7.53261E-06 None None None None I None 2.9967E-05 0 None 0 0 None 0 0 8.99798E-06 0 0
P/A 22454 Fn3-51 4 rs1357187805 0.1013 -1.173 1.0 N 0.828 0.426 0.303123707472 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.01E-06 0
P/A 22454 Fn3-51 4 rs1357187805 0.1013 -1.173 1.0 N 0.828 0.426 0.303123707472 gnomAD-4.0.0 1.59334E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86112E-06 0 0
I/V 22646 Fn3-52 4 rs1348616703 0.1034 None 0.985 N 0.375 0.197 0.40749426699 gnomAD-4.0.0 1.59215E-06 None None None None N None 0 0 None 0 2.78133E-05 None 0 0 0 0 0
A/P 22746 Fn3-53 4 rs1443692023 0.1809 None 0.999 N 0.797 0.365 0.361160317528 gnomAD-4.0.0 6.8577E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.66069E-05
A/S 22746 Fn3-53 4 rs1443692023 0.1033 -1.898 0.957 N 0.355 0.156 0.292787519742 gnomAD-2.1.1 4.08E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.99E-06 0
A/S 22746 Fn3-53 4 rs1443692023 0.1033 -1.898 0.957 N 0.355 0.156 0.292787519742 gnomAD-4.0.0 6.8577E-07 None None None None N None 0 0 None 0 0 None 0 0 9.00278E-07 0 0
A/T 22746 Fn3-53 4 None 0.1434 None 0.992 N 0.647 0.282 0.390531646278 gnomAD-4.0.0 4.11462E-06 None None None None N None 0 0 None 0 0 None 0 0 5.40167E-06 0 0
P/T 22844 Fn3-54 4 None 0.1974 None 0.999 N 0.85 0.323 0.40017627803 gnomAD-4.0.0 1.39938E-06 None None None None N None 0 0 None 0 0 None 0 0 1.82282E-06 0 0
P/A 23043 Fn3-55 4 rs1251404237 0.1112 None 1.0 N 0.825 0.374 0.327419511103 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.66667E-04
P/A 23043 Fn3-55 4 rs1251404237 0.1112 None 1.0 N 0.825 0.374 0.327419511103 gnomAD-4.0.0 6.84516E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65766E-05
P/L 23043 Fn3-55 4 rs773833922 0.1925 -0.824 1.0 D 0.879 0.475 0.73478975765 gnomAD-2.1.1 8.08E-06 None None None None N None 0 0 None 0 0 None 0 None 9.31E-05 0 0
P/L 23043 Fn3-55 4 rs773833922 0.1925 -0.824 1.0 D 0.879 0.475 0.73478975765 gnomAD-4.0.0 4.77844E-06 None None None None N None 0 0 None 0 0 None 3.76903E-05 0 2.86025E-06 0 0
P/S 23043 Fn3-55 4 rs1251404237 0.2405 -1.361 1.0 N 0.838 0.423 0.4018988957 gnomAD-2.1.1 4.04E-06 None None None None N None 0 0 None 0 5.65E-05 None 0 None 0 0 0
P/S 23043 Fn3-55 4 rs1251404237 0.2405 -1.361 1.0 N 0.838 0.423 0.4018988957 gnomAD-4.0.0 1.36903E-06 None None None None N None 0 0 None 0 5.06457E-05 None 0 0 0 0 0
P/L 23142 Fn3-56 4 rs2288572 0.1759 -0.701 0.976 D 0.842 0.434 0.771457117378 gnomAD-2.1.1 4.12E-06 None None None None N None 0 0 None 0 5.7E-05 None 0 None 0 0 0
P/L 23142 Fn3-56 4 rs2288572 0.1759 -0.701 0.976 D 0.842 0.434 0.771457117378 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 1.93949E-04 None 0 0 0 0 0
P/L 23142 Fn3-56 4 rs2288572 0.1759 -0.701 0.976 D 0.842 0.434 0.771457117378 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 1E-03 0 None None None 0 None
P/L 23142 Fn3-56 4 rs2288572 0.1759 -0.701 0.976 D 0.842 0.434 0.771457117378 gnomAD-4.0.0 6.5716E-06 None None None None N None 0 0 None 0 1.94401E-04 None 0 0 0 0 0
P/S 23142 Fn3-56 4 None 0.1562 None 0.976 D 0.823 0.351 0.257292322809 gnomAD-4.0.0 1.60543E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86918E-06 0 0
P/S 23243 Fn3-57 4 rs1221599663 0.3919 -1.267 1.0 N 0.855 0.434 0.34854441366 gnomAD-2.1.1 4.71E-06 None None None None I None 0 0 None 0 0 None 4.24E-05 None 0 0 0
P/S 23243 Fn3-57 4 rs1221599663 0.3919 -1.267 1.0 N 0.855 0.434 0.34854441366 gnomAD-4.0.0 3.39479E-06 None None None None I None 0 0 None 0 0 None 1.95069E-05 0 0 1.60318E-05 0
P/L 23438 Fn3-58 4 None 0.3701 None 1.0 N 0.89 0.486 0.795181792715 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 23535 Fn3-59 4 None 0.2777 None 1.0 D 0.838 0.481 0.663460038712 gnomAD-4.0.0 1.59147E-06 None None None None N None 0 2.28634E-05 None 0 0 None 0 0 0 0 0
P/R 23535 Fn3-59 4 None 0.5482 None 1.0 N 0.873 0.474 0.501685917333 gnomAD-4.0.0 1.59147E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43299E-05 0
P/R 23729 Fn3-60 4 None 0.3629 None 0.999 N 0.887 0.43 0.525258673147 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/T 23729 Fn3-60 4 None 0.2353 None 0.993 N 0.799 0.342 0.450539155747 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/A 23927 Fn3-62 4 None 0.0796 None 0.014 N 0.506 0.193 0.139678290688 gnomAD-4.0.0 4.10568E-06 None None None None N None 0 0 None 0 0 None 0 0 5.39721E-06 0 0
P/Q 23927 Fn3-62 4 None 0.2487 None 0.126 N 0.604 0.368 0.289098819767 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 24125 Fn3-63 4 None 0.1633 None 1.0 D 0.876 0.464 0.744696741112 gnomAD-4.0.0 6.95959E-07 None None None None N None 0 0 None 0 0 None 0 0 9.08617E-07 0 0
P/T 24125 Fn3-63 4 rs1480996647 0.2292 -1.628 1.0 N 0.825 0.417 0.516491959214 gnomAD-2.1.1 8.55E-06 None None None None N None 0 0 None 0 0 None 0 None 0 1.87E-05 0
P/T 24125 Fn3-63 4 rs1480996647 0.2292 -1.628 1.0 N 0.825 0.417 0.516491959214 gnomAD-3.1.2 1.32E-05 None None None None N None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/T 24125 Fn3-63 4 rs1480996647 0.2292 -1.628 1.0 N 0.825 0.417 0.516491959214 gnomAD-4.0.0 2.82183E-05 None None None None N None 0 0 None 0 0 None 0 0 3.75828E-05 0 1.62222E-05
P/L 24225 Fn3-64 4 rs55992239 0.1806 -0.605 1.0 D 0.911 0.485 None gnomAD-2.1.1 8.85E-05 None None None None N None 8.67E-05 0 None 0 1.82304E-04 None 1.42714E-04 None 0 1.09649E-04 0
P/L 24225 Fn3-64 4 rs55992239 0.1806 -0.605 1.0 D 0.911 0.485 None gnomAD-3.1.2 1.05251E-04 None None None None N None 4.83E-05 6.56E-05 0 0 0 None 0 0 1.76507E-04 2.07383E-04 0
P/L 24225 Fn3-64 4 rs55992239 0.1806 -0.605 1.0 D 0.911 0.485 None 1000 genomes 1.99681E-04 None None None None N None 0 0 None None 0 0 None None None 1E-03 None
P/L 24225 Fn3-64 4 rs55992239 0.1806 -0.605 1.0 D 0.911 0.485 None gnomAD-4.0.0 1.7709E-04 None None None None N None 8.37474E-05 2.31825E-05 None 0 4.58253E-05 None 0 0 2.17721E-04 5.58005E-05 1.374E-04
P/Q 24225 Fn3-64 4 None 0.1655 None 1.0 N 0.882 0.477 0.535247687934 gnomAD-4.0.0 7.34635E-07 None None None None N None 0 0 None 0 0 None 0 0 9.37647E-07 0 0
P/L 24326 Fn3-65 4 None 0.326 None 1.0 D 0.892 0.45 0.722475063491 gnomAD-4.0.0 1.59308E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43563E-05 0
P/S 24326 Fn3-65 4 None 0.3436 None 1.0 N 0.846 0.376 0.39843156188 gnomAD-4.0.0 1.20033E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
P/A 24522 Fn3-66 4 rs1195696847 0.0769 -1.712 0.001 N 0.449 0.167 0.212008924253 gnomAD-2.1.1 4.03E-06 None None None None N None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/A 24522 Fn3-66 4 rs1195696847 0.0769 -1.712 0.001 N 0.449 0.167 0.212008924253 gnomAD-4.0.0 1.59198E-06 None None None None N None 0 2.28676E-05 None 0 0 None 0 0 0 0 0
P/R 24522 Fn3-66 4 None 0.3936 None 0.993 N 0.836 0.447 0.551177841964 gnomAD-4.0.0 1.59202E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43303E-05 0
P/L 24619 Fn3-67 4 None 0.5982 None 1.0 D 0.895 0.5 0.545519808136 gnomAD-4.0.0 1.59284E-06 None None None None N None 0 0 None 0 0 None 0 0 2.86105E-06 0 0
P/L 24911 Fn3-69 4 rs750688079 0.2444 -0.658 0.999 N 0.755 0.439 0.74914240937 gnomAD-2.1.1 4.03E-06 None None None None I None 0 2.9E-05 None 0 0 None 0 None 0 0 0
P/L 24911 Fn3-69 4 rs750688079 0.2444 -0.658 0.999 N 0.755 0.439 0.74914240937 gnomAD-4.0.0 2.05305E-06 None None None None I None 2.98989E-05 4.47287E-05 None 0 0 None 0 0 0 0 0
P/S 24911 Fn3-69 4 None 0.243 None 0.905 N 0.423 0.199 0.374434639691 gnomAD-4.0.0 1.59204E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85948E-06 0 0
P/L 25009 Fn3-70 4 rs1474848898 0.2443 -0.827 0.999 N 0.841 0.344 0.675682906761 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/L 25009 Fn3-70 4 rs1474848898 0.2443 -0.827 0.999 N 0.841 0.344 0.675682906761 gnomAD-4.0.0 3.18404E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86599E-05 0
P/R 25207 Fn3-71 4 rs72646900 0.2662 -0.823 0.957 N 0.886 0.422 0.439339381091 gnomAD-2.1.1 1.79E-05 None None None None I None 0 0 None 0 0 None 0 None 0 3.93E-05 0
P/R 25207 Fn3-71 4 rs72646900 0.2662 -0.823 0.957 N 0.886 0.422 0.439339381091 gnomAD-3.1.2 1.97E-05 None None None None I None 0 0 0 0 0 None 0 0 4.41E-05 0 0
P/R 25207 Fn3-71 4 rs72646900 0.2662 -0.823 0.957 N 0.886 0.422 0.439339381091 gnomAD-4.0.0 2.16963E-05 None None None None I None 0 0 None 0 0 None 0 0 2.88236E-05 0 1.60185E-05
P/H 25408 Fn3-73 4 None 0.5652 None 1.0 D 0.899 0.454 0.563728453957 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/L 25408 Fn3-73 4 None 0.3068 None 1.0 N 0.895 0.442 0.648735566516 gnomAD-4.0.0 1.20032E-06 None None None None N None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
P/L 25604 Fn3-74 4 rs1707251307 0.163 None 0.707 D 0.777 0.404 0.520694202979 gnomAD-4.0.0 2.0538E-06 None None None None I None 0 0 None 0 0 None 1.87441E-05 0 1.79963E-06 0 0
P/L 25701 Fn3-75 4 rs374033036 0.3459 -0.893 1.0 N 0.914 0.542 None gnomAD-2.1.1 8.06E-06 None None None None N None 1.29299E-04 0 None 0 0 None 0 None 0 0 0
P/L 25701 Fn3-75 4 rs374033036 0.3459 -0.893 1.0 N 0.914 0.542 None gnomAD-4.0.0 3.18486E-06 None None None None N None 1.13302E-04 0 None 0 0 None 0 0 0 0 0
P/L 25893 Fn3-76 4 None 0.1529 None 1.0 D 0.901 0.489 0.675998447366 gnomAD-4.0.0 2.0532E-06 None None None None I None 0 0 None 0 0 None 0 0 2.69884E-06 0 0
P/R 25893 Fn3-76 4 None 0.2134 None 1.0 N 0.907 0.474 0.546131560702 gnomAD-4.0.0 6.84399E-07 None None None None I None 0 0 None 0 0 None 0 0 8.99612E-07 0 0
P/S 25893 Fn3-76 4 rs1462410139 0.2007 -2.027 1.0 N 0.852 0.447 0.430579932962 gnomAD-2.1.1 2.01E-05 None None None None I None 0 1.45197E-04 None 0 0 None 0 None 0 0 0
P/S 25893 Fn3-76 4 rs1462410139 0.2007 -2.027 1.0 N 0.852 0.447 0.430579932962 gnomAD-3.1.2 9.21E-05 None None None None I None 0 9.18153E-04 0 0 0 None 0 0 0 0 0
P/S 25893 Fn3-76 4 rs1462410139 0.2007 -2.027 1.0 N 0.852 0.447 0.430579932962 gnomAD-4.0.0 2.43573E-05 None None None None I None 0 3.22318E-04 None 0 0 None 0 0 0 0 0
P/H 25993 Fn3-77 4 rs771646684 0.5744 None 0.999 D 0.889 0.445 0.604997275223 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/H 25993 Fn3-77 4 rs771646684 0.5744 None 0.999 D 0.889 0.445 0.604997275223 gnomAD-4.0.0 1.23962E-06 None None None None I None 2.67173E-05 0 None 0 0 None 0 0 0 0 0
P/L 25993 Fn3-77 4 rs771646684 0.2562 -0.765 0.976 N 0.845 0.434 0.660965098231 gnomAD-2.1.1 1.43E-05 None None None None I None 0 0 None 0 0 None 9.8E-05 None 0 7.82E-06 0
P/L 25993 Fn3-77 4 rs771646684 0.2562 -0.765 0.976 N 0.845 0.434 0.660965098231 gnomAD-3.1.2 6.58E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/L 25993 Fn3-77 4 rs771646684 0.2562 -0.765 0.976 N 0.845 0.434 0.660965098231 gnomAD-4.0.0 6.81791E-06 None None None None I None 0 0 None 0 0 None 0 0 3.39092E-06 6.58776E-05 1.60154E-05
P/S 26091 Fn3-78 4 None 0.1923 None 1.0 N 0.872 0.481 0.39709148275 gnomAD-4.0.0 6.84317E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99588E-07 0 0
P/T 26091 Fn3-78 4 rs1706513833 0.2253 None 1.0 N 0.865 0.498 0.458283960492 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 26091 Fn3-78 4 rs1706513833 0.2253 None 1.0 N 0.865 0.498 0.458283960492 gnomAD-4.0.0 1.23973E-06 None None None None N None 0 0 None 0 0 None 0 0 1.69552E-06 0 0
P/R 26289 Fn3-79 4 None 0.4072 None 1.0 D 0.914 0.605 0.582512623681 gnomAD-4.0.0 1.37568E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80423E-06 0 0
P/S 26289 Fn3-79 4 rs1030641242 0.3784 None 1.0 N 0.874 0.53 0.465381546717 gnomAD-3.1.2 6.58E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 26289 Fn3-79 4 rs1030641242 0.3784 None 1.0 N 0.874 0.53 0.465381546717 gnomAD-4.0.0 2.48957E-06 None None None None N None 0 0 None 0 0 None 0 0 3.39892E-06 0 0
P/L 26389 Fn3-80 4 rs760307077 0.1581 -0.72 0.967 N 0.745 0.496 0.651006993216 gnomAD-2.1.1 8.05E-06 None None None None N None 0 0 None 0 0 None 6.54E-05 None 0 0 0
P/L 26389 Fn3-80 4 rs760307077 0.1581 -0.72 0.967 N 0.745 0.496 0.651006993216 gnomAD-4.0.0 3.18323E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86566E-05 0
P/L 26490 Fn3-81 4 rs746317804 0.2234 -0.761 0.549 D 0.795 0.282 None gnomAD-2.1.1 8.06E-06 None None None None I None 1.29282E-04 0 None 0 0 None 0 None 0 0 0
P/L 26490 Fn3-81 4 rs746317804 0.2234 -0.761 0.549 D 0.795 0.282 None gnomAD-3.1.2 1.97E-05 None None None None I None 7.24E-05 0 0 0 0 None 0 0 0 0 0
P/L 26490 Fn3-81 4 rs746317804 0.2234 -0.761 0.549 D 0.795 0.282 None gnomAD-4.0.0 7.69371E-06 None None None None I None 6.76979E-05 0 None 0 0 None 0 0 0 2.68039E-05 0
P/L 26686 Fn3-82 4 rs867306848 0.1883 -0.669 0.999 N 0.826 0.424 0.657421573829 gnomAD-2.1.1 4.02E-06 None None None None I None 6.46E-05 0 None 0 0 None 0 None 0 0 0
P/L 26686 Fn3-82 4 rs867306848 0.1883 -0.669 0.999 N 0.826 0.424 0.657421573829 gnomAD-3.1.2 6.58E-06 None None None None I None 2.41E-05 0 0 0 0 None 0 0 0 0 0
P/L 26686 Fn3-82 4 rs867306848 0.1883 -0.669 0.999 N 0.826 0.424 0.657421573829 gnomAD-4.0.0 6.57549E-06 None None None None I None 2.41464E-05 0 None 0 0 None 0 0 0 0 0
P/S 26783 Fn3-83 4 None 0.2106 None 0.262 N 0.495 0.205 0.231231049324 gnomAD-4.0.0 1.59167E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43279E-05 0
P/R 26975 Fn3-84 4 None 0.3238 None 0.994 D 0.925 0.584 0.487348339145 gnomAD-4.0.0 1.59177E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43324E-05 0
P/S 26975 Fn3-84 4 None 0.2426 None 0.994 N 0.866 0.464 0.352476196916 gnomAD-4.0.0 6.84295E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99538E-07 0 0
P/T 26975 Fn3-84 4 rs1283579585 0.1901 -1.373 0.988 N 0.86 0.516 0.432266382184 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/T 26975 Fn3-84 4 rs1283579585 0.1901 -1.373 0.988 N 0.86 0.516 0.432266382184 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/T 26975 Fn3-84 4 rs1283579585 0.1901 -1.373 0.988 N 0.86 0.516 0.432266382184 gnomAD-4.0.0 1.85937E-06 None None None None N None 0 1.66739E-05 None 0 0 None 0 0 1.69536E-06 0 0
P/S 27075 Fn3-85 4 None 0.2259 None 0.956 N 0.656 0.305 0.321108458156 gnomAD-4.0.0 1.36959E-05 None None None None I None 0 0 None 0 0 None 0 0 1.70963E-05 0 1.65859E-05
P/T 27075 Fn3-85 4 None 0.2495 None 0.978 N 0.697 0.323 0.377097596864 gnomAD-4.0.0 6.84796E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.16393E-05 0
P/A 27173 Fn3-86 4 rs754325718 0.0848 -1.674 1.0 N 0.85 0.274 None gnomAD-2.1.1 6.44E-05 None None None None N None 4.13E-05 0 None 0 0 None 0 None 3.60144E-04 5.48E-05 1.40726E-04
P/A 27173 Fn3-86 4 rs754325718 0.0848 -1.674 1.0 N 0.85 0.274 None gnomAD-3.1.2 1.24972E-04 None None None None N None 0 2.62433E-04 0 0 0 None 1.03774E-03 0 5.88E-05 0 0
P/A 27173 Fn3-86 4 rs754325718 0.0848 -1.674 1.0 N 0.85 0.274 None gnomAD-4.0.0 6.9423E-05 None None None None N None 0 6.67334E-05 None 0 0 None 6.09623E-04 0 5.59486E-05 0 4.80477E-05
P/L 27173 Fn3-86 4 rs766831675 0.3018 None 1.0 N 0.902 0.519 0.698133738195 gnomAD-4.0.0 1.09495E-05 None None None None N None 0 0 None 0 0 None 0 0 1.25938E-05 0 3.31411E-05
P/R 27372 Fn3-87 4 None 0.2733 None 0.142 N 0.591 0.511 0.364141725642 gnomAD-4.0.0 1.59134E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43275E-05 0
P/S 27372 Fn3-87 4 rs1287205407 0.2819 -1.638 0.988 N 0.824 0.428 0.416581338634 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
P/T 27372 Fn3-87 4 rs1287205407 0.253 -1.53 0.988 N 0.813 0.423 0.485634191555 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.9E-06 0
P/T 27372 Fn3-87 4 rs1287205407 0.253 -1.53 0.988 N 0.813 0.423 0.485634191555 gnomAD-4.0.0 1.59136E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85855E-06 0 0
P/L 27472 Fn3-88 4 rs747864468 0.162 -0.782 0.896 N 0.851 0.478 0.661443717991 gnomAD-2.1.1 7.14E-06 None None None None N None 4.13E-05 0 None 0 0 None 0 None 0 7.81E-06 0
P/L 27472 Fn3-88 4 rs747864468 0.162 -0.782 0.896 N 0.851 0.478 0.661443717991 gnomAD-3.1.2 1.31E-05 None None None None N None 4.83E-05 0 0 0 0 None 0 0 0 0 0
P/L 27472 Fn3-88 4 rs747864468 0.162 -0.782 0.896 N 0.851 0.478 0.661443717991 gnomAD-4.0.0 3.09857E-06 None None None None N None 4.0047E-05 0 None 0 0 None 0 0 1.69524E-06 0 0
P/R 27472 Fn3-88 4 None 0.153 None 0.984 N 0.869 0.467 0.528409864224 gnomAD-4.0.0 6.84205E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99475E-07 0 0
A/S 27769 Fn3-90 4 None 0.1127 None 0.958 N 0.735 0.28 0.323886383625 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
A/V 27769 Fn3-90 4 None 0.22 None 0.979 N 0.778 0.418 0.491112125781 gnomAD-4.0.0 5.47655E-06 None None None None I None 0 0 None 0 0 None 0 0 7.1976E-06 0 0
P/R 28058 Fn3-92 4 rs1293214241 0.2284 -0.035 1.0 D 0.908 0.492 0.520161069619 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.92E-06 0
P/R 28058 Fn3-92 4 rs1293214241 0.2284 -0.035 1.0 D 0.908 0.492 0.520161069619 gnomAD-4.0.0 3.18617E-06 None None None None N None 0 0 None 0 0 None 0 0 5.72384E-06 0 0
P/S 28058 Fn3-92 4 None 0.17 None 1.0 N 0.84 0.359 0.38225645794 gnomAD-4.0.0 1.59313E-06 None None None None N None 0 0 None 0 0 None 0 0 2.862E-06 0 0
P/L 28157 Fn3-93 4 None 0.322 None 0.988 D 0.87 0.516 0.740553466771 gnomAD-4.0.0 1.60947E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.45366E-05 0
P/L 28255 Fn3-94 4 rs1703598147 0.2372 None 0.999 D 0.848 0.495 0.782479200985 gnomAD-4.0.0 1.20032E-06 None None None None N None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
P/S 28255 Fn3-94 4 rs1703599575 0.2098 None 0.905 N 0.453 0.334 0.249502417897 gnomAD-3.1.2 6.58E-06 None None None None N None 0 6.57E-05 0 0 0 None 0 0 0 0 0
P/S 28255 Fn3-94 4 rs1703599575 0.2098 None 0.905 N 0.453 0.334 0.249502417897 gnomAD-4.0.0 6.5799E-06 None None None None N None 0 6.56513E-05 None 0 0 None 0 0 0 0 0
P/S 28453 Fn3-95 4 None 0.2637 None 1.0 N 0.861 0.443 0.285698343383 gnomAD-4.0.0 2.40064E-06 None None None None N None 0 0 None 0 0 None 0 0 2.625E-06 0 0
P/L 28553 Fn3-96 4 rs1303551225 0.1543 -0.752 0.822 D 0.815 0.401 0.413241256734 gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 1.9305E-04 None 0 0 0 2.07297E-04 0
P/L 28553 Fn3-96 4 rs1303551225 0.1543 -0.752 0.822 D 0.815 0.401 0.413241256734 gnomAD-4.0.0 5.12755E-06 None None None None I None 0 0 None 0 7.29359E-05 None 0 0 0 1.34117E-05 0
P/L 28654 Fn3-97 4 None 0.3203 None 1.0 N 0.908 0.42 0.772784792456 gnomAD-4.0.0 3.18265E-06 None None None None N None 0 0 None 0 0 None 0 0 5.7169E-06 0 0
P/L 28945 Fn3-99 4 None 0.2142 None 1.0 N 0.905 0.463 0.705626407511 gnomAD-4.0.0 1.20033E-06 None None None None N None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
P/T 28945 Fn3-99 4 None 0.2353 None 1.0 N 0.846 0.382 0.480198768302 gnomAD-4.0.0 1.5995E-06 None None None None N None 0 0 None 0 0 None 1.90498E-05 0 0 0 0
P/L 29140 Fn3-100 4 rs1483374179 0.1499 -0.865 0.999 N 0.832 0.419 0.674589302959 gnomAD-2.1.1 4.03E-06 None None None None N None 0 0 None 0 5.57E-05 None 0 None 0 0 0
P/L 29140 Fn3-100 4 rs1483374179 0.1499 -0.865 0.999 N 0.832 0.419 0.674589302959 gnomAD-4.0.0 1.59303E-06 None None None None N None 0 0 None 0 2.77254E-05 None 0 0 0 0 0
P/S 29140 Fn3-100 4 None 0.2499 None 0.992 N 0.776 0.375 0.372087925617 gnomAD-4.0.0 1.36909E-06 None None None None N None 0 0 None 0 0 None 0 0 8.99425E-07 1.15937E-05 0
P/S 29240 Fn3-101 4 None 0.318 None 0.956 N 0.706 0.349 0.316198179892 gnomAD-4.0.0 1.20033E-06 None None None None I None 0 0 None 0 0 None 0 0 1.31251E-06 0 0
P/T 29240 Fn3-101 4 None 0.3623 None 0.978 N 0.736 0.384 0.502878934189 gnomAD-4.0.0 3.60098E-06 None None None None I None 0 0 None 0 0 None 0 0 3.93752E-06 0 0
P/H 29338 Fn3-102 4 rs1274987792 0.5916 -1.183 1.0 D 0.894 0.475 0.554315986709 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 8.97E-06 0
P/H 29338 Fn3-102 4 rs1274987792 0.5916 -1.183 1.0 D 0.894 0.475 0.554315986709 gnomAD-4.0.0 1.59237E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85914E-06 0 0
P/S 29338 Fn3-102 4 rs774162189 0.3028 -1.582 0.987 N 0.811 0.435 0.359763055319 gnomAD-2.1.1 8.5E-05 None None None None N None 0 0 None 0 0 None 0 None 1.396E-04 1.52516E-04 1.66556E-04
P/S 29338 Fn3-102 4 rs774162189 0.3028 -1.582 0.987 N 0.811 0.435 0.359763055319 gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 0 None 9.42E-05 0 2.94E-05 0 0
P/S 29338 Fn3-102 4 rs774162189 0.3028 -1.582 0.987 N 0.811 0.435 0.359763055319 gnomAD-4.0.0 3.22324E-05 None None None None N None 0 0 None 0 0 None 1.56362E-04 0 2.79736E-05 0 1.44129E-04
P/T 29338 Fn3-102 4 rs774162189 0.3374 None 0.993 N 0.831 0.438 0.438913950225 gnomAD-4.0.0 6.84413E-07 None None None None N None 0 0 None 0 0 None 0 0 0 0 1.65695E-05
P/L 29536 Fn3-103 4 rs928055260 0.1166 None 1.0 N 0.873 0.469 0.721917965023 gnomAD-4.0.0 1.59177E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.02535E-05
P/T 29737 Fn3-105 4 None 0.2294 None 0.003 N 0.401 0.253 0.33835085245 gnomAD-4.0.0 1.64725E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.51446E-05 0
A/D 29936 Fn3-106 4 None 0.4493 None 0.565 N 0.749 0.443 0.53837629882 gnomAD-4.0.0 1.59813E-06 None None None None N None 0 0 None 0 2.77917E-05 None 0 0 0 0 0
A/T 29936 Fn3-106 4 rs188667007 0.128 -1.269 0.008 N 0.323 0.206 0.27855597813 gnomAD-2.1.1 3.19E-05 None None None None N None 0 0 None 0 0 None 0 None 0 6.48E-05 0
A/T 29936 Fn3-106 4 rs188667007 0.128 -1.269 0.008 N 0.323 0.206 0.27855597813 gnomAD-4.0.0 4.79461E-06 None None None None N None 0 0 None 0 0 None 0 0 8.62203E-06 0 0
K/M 30227 Fn3-108 4 None 0.1743 None 0.966 N 0.494 0.274 0.233785782151 gnomAD-4.0.0 2.05314E-06 None None None None N None 0 0 None 0 0 None 0 0 1.79917E-06 0 1.65722E-05
P/L 30327 Fn3-109 4 rs770107107 0.1279 -0.621 0.338 N 0.759 0.414 0.604789236398 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 3.27E-05 None 0 0 0
P/L 30327 Fn3-109 4 rs770107107 0.1279 -0.621 0.338 N 0.759 0.414 0.604789236398 gnomAD-4.0.0 3.18298E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.86582E-05 0
P/R 30327 Fn3-109 4 rs770107107 0.224 -0.189 0.782 N 0.754 0.451 0.464098490096 gnomAD-2.1.1 1.21E-05 None None None None N None 0 0 None 0 0 None 0 None 0 2.66E-05 0
P/R 30327 Fn3-109 4 rs770107107 0.224 -0.189 0.782 N 0.754 0.451 0.464098490096 gnomAD-4.0.0 3.18298E-06 None None None None N None 0 0 None 0 0 None 0 0 2.85905E-06 0 3.02425E-05
P/S 30327 Fn3-109 4 None 0.117 None 0.013 N 0.433 0.139 0.149567049428 gnomAD-4.0.0 6.84244E-07 None None None None N None 0 0 None 0 0 None 0 0 8.99536E-07 0 0
P/L 30425 Fn3-110 4 None 0.441 None 1.0 N 0.891 0.441 0.795852534775 gnomAD-4.0.0 2.06199E-06 None None None None N None 0 0 None 0 0 None 0 0 0 2.36312E-05 1.6624E-05
P/Q 30425 Fn3-110 4 rs1373323809 0.5004 -1.648 1.0 N 0.877 0.425 0.575346514103 gnomAD-2.1.1 4.11E-06 None None None None N None 0 0 None 0 5.64E-05 None 0 None 0 0 0
P/Q 30425 Fn3-110 4 rs1373323809 0.5004 -1.648 1.0 N 0.877 0.425 0.575346514103 gnomAD-4.0.0 1.37466E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 3.3248E-05
K/E 30622 Fn3-111 4 rs756685124 0.1038 None 0.002 N 0.199 0.148 0.173771789658 gnomAD-4.0.0 4.95021E-06 None None None None I None 0 0 None 0 0 None 0 0 6.42002E-06 0 0
K/N 30622 Fn3-111 4 None 0.2345 None 0.351 N 0.471 0.077 0.104622674875 gnomAD-4.0.0 1.20032E-06 None None None None I None 6.33473E-05 0 None 0 0 None 0 0 0 0 0
A/V 30722 Fn3-112 4 rs2154148189 0.185 None 0.928 N 0.797 0.354 0.533179623451 gnomAD-4.0.0 6.88776E-07 None None None None N None 3.0259E-05 0 None 0 0 None 0 0 0 0 0
P/R 30824 Fn3-113 4 rs1364127443 0.1821 -0.178 0.055 N 0.672 0.352 0.40417439687 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 5.58E-05 None 0 None 0 0 0
P/R 30824 Fn3-113 4 rs1364127443 0.1821 -0.178 0.055 N 0.672 0.352 0.40417439687 gnomAD-4.0.0 1.59125E-06 None None None None I None 0 0 None 0 2.775E-05 None 0 0 0 0 0
P/S 30824 Fn3-113 4 rs757687130 0.1079 -1.063 0.005 N 0.431 0.157 0.159798565429 gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
P/S 30824 Fn3-113 4 rs757687130 0.1079 -1.063 0.005 N 0.431 0.157 0.159798565429 gnomAD-3.1.2 6.57E-06 None None None None I None 0 0 0 0 0 None 0 0 1.47E-05 0 0
P/S 30824 Fn3-113 4 rs757687130 0.1079 -1.063 0.005 N 0.431 0.157 0.159798565429 gnomAD-4.0.0 8.96778E-06 None None None None I None 0 0 None 0 0 None 0 0 1.67495E-05 0 0
P/L 31019 Fn3-114 4 rs772541126 0.1611 None 0.999 D 0.851 0.464 None gnomAD-4.0.0 1.5911E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85804E-06 0 0
P/Q 31019 Fn3-114 4 rs772541126 0.2147 -1.26 0.999 D 0.843 0.453 0.488897681448 gnomAD-2.1.1 8.05E-06 None None None None I None 0 0 None 0 0 None 0 None 0 1.78E-05 0
P/Q 31019 Fn3-114 4 rs772541126 0.2147 -1.26 0.999 D 0.843 0.453 0.488897681448 gnomAD-4.0.0 3.1822E-06 None None None None I None 0 0 None 0 0 None 0 0 5.71608E-06 0 0
P/S 31019 Fn3-114 4 None 0.1882 None 0.999 N 0.796 0.377 0.377799810692 gnomAD-4.0.0 1.59112E-06 None None None None I None 0 0 None 0 0 None 1.88246E-05 0 0 0 0
A/T 31411 Fn3-117 4 rs745652405 0.1539 -1.436 0.98 N 0.746 0.307 None gnomAD-2.1.1 4.01E-05 None None None None N None 0 0 None 0 2.0674E-04 None 3.41E-05 None 0 3.97E-05 1.4497E-04
A/T 31411 Fn3-117 4 rs745652405 0.1539 -1.436 0.98 N 0.746 0.307 None gnomAD-3.1.2 1.97E-05 None None None None N None 0 0 0 0 3.85208E-04 None 0 0 0 2.07469E-04 0
A/T 31411 Fn3-117 4 rs745652405 0.1539 -1.436 0.98 N 0.746 0.307 None gnomAD-4.0.0 1.68125E-05 None None None None N None 0 0 None 0 1.33935E-04 None 1.56833E-05 0 1.10578E-05 3.33104E-05 6.44891E-05
P/L 31711 Fn3-119 4 None 0.1432 None 0.997 D 0.705 0.485 0.653323239085 gnomAD-4.0.0 6.88534E-07 None None None None N None 0 0 None 0 0 None 0 0 9.0413E-07 0 0
P/T 31810 Fn3-120 4 None 0.1179 None 0.117 N 0.668 0.349 0.326074293725 gnomAD-4.0.0 1.59393E-06 None None None None N None 0 0 None 0 0 None 0 0 0 1.43377E-05 0
P/L 32108 Fn3-122 4 None 0.2601 None 1.0 N 0.808 0.488 0.713599342433 gnomAD-4.0.0 1.3971E-06 None None None None N None 0 0 None 0 0 None 0 0 1.81602E-06 0 0
P/R 32108 Fn3-122 4 None 0.3231 None 1.0 N 0.813 0.483 0.536474986538 gnomAD-4.0.0 6.98552E-07 None None None None N None 0 0 None 0 0 None 0 0 9.08008E-07 0 0
P/S 32108 Fn3-122 4 rs779955397 0.2317 -1.383 1.0 N 0.778 0.443 0.451882325854 gnomAD-2.1.1 4.39E-06 None None None None N None 0 0 None 0 0 None 0 None 0 9.31E-06 0
P/S 32108 Fn3-122 4 rs779955397 0.2317 -1.383 1.0 N 0.778 0.443 0.451882325854 gnomAD-4.0.0 6.97935E-07 None None None None N None 0 0 None 0 0 None 0 0 9.07316E-07 0 0
V/A 32205 Fn3-123 4 rs922829895 0.1372 None 0.002 N 0.313 0.085 0.326616659874 gnomAD-4.0.0 1.59116E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85811E-06 0 0
V/L 32205 Fn3-123 4 None 0.1995 None 0.094 N 0.481 0.122 0.443797312901 gnomAD-4.0.0 1.59116E-06 None None None None I None 0 0 None 0 0 None 0 0 0 1.43271E-05 0
V/M 32205 Fn3-123 4 rs372312129 0.1899 -1.286 0.781 N 0.649 0.198 None gnomAD-2.1.1 4.02E-06 None None None None I None 0 0 None 0 0 None 0 None 0 8.87E-06 0
V/M 32205 Fn3-123 4 rs372312129 0.1899 -1.286 0.781 N 0.649 0.198 None gnomAD-4.0.0 1.59116E-06 None None None None I None 0 0 None 0 0 None 0 0 2.85809E-06 0 0
P/L 32402 Fn3-124 4 None 0.153 None 0.704 N 0.685 0.36 0.424549175451 gnomAD-4.0.0 6.89587E-07 None None None None I None 0 0 None 0 0 None 0 0 0 1.17195E-05 0
P/R 32402 Fn3-124 4 rs761156054 0.2931 -0.456 0.996 N 0.73 0.368 None gnomAD-2.1.1 2.18E-05 None None None None I None 0 2.86E-05 None 0 0 None 3.38E-05 None 0 3.18E-05 0
P/R 32402 Fn3-124 4 rs761156054 0.2931 -0.456 0.996 N 0.73 0.368 None gnomAD-3.1.2 1.32E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/R 32402 Fn3-124 4 rs761156054 0.2931 -0.456 0.996 N 0.73 0.368 None gnomAD-4.0.0 1.68515E-05 None None None None I None 0 1.67802E-05 None 0 0 None 0 4.97347E-04 1.62169E-05 2.21852E-05 3.23217E-05
P/S 32402 Fn3-124 4 rs764632520 0.2311 -1.441 0.959 N 0.697 0.338 0.250039746154 gnomAD-2.1.1 4.1E-06 None None None None I None 6.48E-05 0 None 0 0 None 0 None 0 0 0
P/S 32402 Fn3-124 4 rs764632520 0.2311 -1.441 0.959 N 0.697 0.338 0.250039746154 gnomAD-4.0.0 2.0691E-06 None None None None I None 3.01386E-05 0 None 0 0 None 0 0 1.81261E-06 0 0
P/T 32402 Fn3-124 4 rs764632520 0.1746 -1.398 0.92 N 0.683 0.313 None gnomAD-2.1.1 2.18E-05 None None None None I None 0 2.86E-05 None 0 0 None 3.38E-05 None 0 3.18E-05 0
P/T 32402 Fn3-124 4 rs764632520 0.1746 -1.398 0.92 N 0.683 0.313 None gnomAD-3.1.2 1.31E-05 None None None None I None 0 0 0 0 0 None 0 0 2.94E-05 0 0
P/T 32402 Fn3-124 4 rs764632520 0.1746 -1.398 0.92 N 0.683 0.313 None gnomAD-4.0.0 1.68537E-05 None None None None I None 0 1.67791E-05 None 0 0 None 0 4.97183E-04 1.622E-05 2.21921E-05 3.23206E-05
P/L 32502 Fn3-125 4 None 0.1809 None 0.026 N 0.604 0.358 0.543691374674 gnomAD-4.0.0 1.37501E-06 None None None None N None 0 0 None 0 0 None 0 0 1.80591E-06 0 0
K/R 32603 Fn3-126 4 rs778929590 0.0906 -0.414 0.006 N 0.348 0.052 0.184867976434 gnomAD-2.1.1 4.05E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.66945E-04
K/R 32603 Fn3-126 4 rs778929590 0.0906 -0.414 0.006 N 0.348 0.052 0.184867976434 gnomAD-3.1.2 6.57E-06 None None None None N None 0 0 0 0 0 None 0 0 0 0 4.77555E-04
K/R 32603 Fn3-126 4 rs778929590 0.0906 -0.414 0.006 N 0.348 0.052 0.184867976434 gnomAD-4.0.0 6.57047E-06 None None None None N None 0 0 None 0 0 None 0 0 0 0 4.77555E-04
P/T 32899 Fn3-128 4 rs199689531 0.3704 None 1.0 N 0.689 0.401 None gnomAD-3.1.2 1.97E-05 None None None None N None 7.24E-05 0 0 0 0 None 0 0 0 0 0
P/T 32899 Fn3-128 4 rs199689531 0.3704 None 1.0 N 0.689 0.401 None gnomAD-4.0.0 1.9713E-05 None None None None N None 7.23624E-05 0 None 0 0 None 0 0 0 0 0
K/E 33293 Fn3-130 4 None 0.2147 None 0.959 N 0.489 0.247 0.323886383625 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
K/I 33293 Fn3-130 4 None 0.1975 None 0.061 N 0.36 0.187 0.455722563999 gnomAD-4.0.0 1.20032E-06 None None None None I None 0 0 None 0 0 None 0 0 1.3125E-06 0 0
A/P 33395 Fn3-131 4 rs761311859 0.0966 None 0.295 N 0.769 0.158 0.152612264143 gnomAD-4.0.0 2.23571E-06 None None None None N None 0 0 None 0 0 None 0 0 1.88724E-06 0 1.8074E-05
A/T 33395 Fn3-131 4 rs761311859 0.0801 None None N 0.371 0.174 0.144782658237 gnomAD-4.0.0 2.98095E-06 None None None None N None 0 0 None 0 0 None 0 0 3.77448E-06 0 0
P/R 33692 Fn3-132 4 rs755832382 0.6338 -0.729 0.973 N 0.867 0.418 0.60087810649 gnomAD-2.1.1 4.02E-06 None None None None N None 0 0 None 0 0 None 0 None 0 0 1.65618E-04
P/R 33692 Fn3-132 4 rs755832382 0.6338 -0.729 0.973 N 0.867 0.418 0.60087810649 gnomAD-4.0.0 1.59118E-06 None None None None N None 0 0 None 0 0 None 0 2.41196E-04 0 0 0

Titin has multiple isoforms, the longest being the theoretical IC (inferred complete) isoform which contains all 363 in-frame titin exons. Here all isoform positions have been mapped onto the IC sequence, with an exception being the C-terminal of the much shorter novex-3 isoform. This contains the out of frame exon 48 which cannot be mapped to the other isoforms.